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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tfcp2+tfcp2l1+ubp1

Z-value: 2.16

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Transcription factors associated with tfcp2+tfcp2l1+ubp1

Gene Symbol Gene ID Gene Info
ENSDARG00000018000 upstream binding protein 1
ENSDARG00000029497 transcription factor CP2-like 1
ENSDARG00000060306 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfcp2dr11_v1_chr23_-_33680265_336802650.381.9e-04Click!
tfcp2l1dr11_v1_chr9_+_38292947_38292947-0.363.3e-04Click!
ubp1dr11_v1_chr19_+_42806812_428068140.303.3e-03Click!

Activity profile of tfcp2+tfcp2l1+ubp1 motif

Sorted Z-values of tfcp2+tfcp2l1+ubp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_27647845 36.85 ENSDART00000151625
si:ch211-157c3.4
chr10_-_15048781 36.37 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
chr5_+_39667272 23.22 ENSDART00000085388
bone morphogenetic protein 3
chr21_+_25688388 22.67 ENSDART00000125709
bicaudal-D-related protein 2
chr12_-_28794957 21.72 ENSDART00000020667
oxysterol binding protein-like 7
chr5_+_15203421 21.53 ENSDART00000040826
T-box 1
chr16_+_23961276 19.43 ENSDART00000192754
apolipoprotein Eb
chr10_-_36793412 18.96 ENSDART00000185966
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr24_+_20960216 18.95 ENSDART00000133008
si:ch211-161h7.8
chr8_+_36142734 17.87 ENSDART00000159361
ENSDART00000161194
major histocompatibility complex class II integral membrane beta chain gene
chr9_-_45602978 17.62 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr24_+_38671054 17.21 ENSDART00000154214
si:ch73-70c5.1
chr22_-_6404807 17.04 ENSDART00000149399
ENSDART00000063420
si:rp71-1i20.2
chr8_-_3312384 16.55 ENSDART00000035965
fucosyltransferase 9b
chr7_+_20503344 16.38 ENSDART00000157699
si:dkey-19b23.12
chr5_+_26204561 15.99 ENSDART00000137178
MARVEL domain containing 2b
chr10_+_36662640 15.75 ENSDART00000063359
uncoupling protein 2
chr20_+_26916639 15.54 ENSDART00000077787
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 2
chr17_-_2039511 15.24 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr12_-_46145635 14.93 ENSDART00000074682
zgc:153932
chr25_+_10416583 14.92 ENSDART00000073907
ets homologous factor
chr22_+_22021936 14.77 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr9_-_443451 14.65 ENSDART00000165642
si:dkey-11f4.14
chr23_+_18779043 14.47 ENSDART00000158267
epithelial membrane protein 3b
chr5_-_37116265 14.33 ENSDART00000057613
interleukin 13 receptor, alpha 2
chr15_+_22014029 13.97 ENSDART00000079504
ankyrin repeat and kinase domain containing 1
chr2_-_15563194 12.93 ENSDART00000049589
collagen, type XI, alpha 1b
chr12_-_46252062 12.84 ENSDART00000153223
si:ch211-226h7.5
chr15_+_46329149 12.72 ENSDART00000128404
si:ch1073-340i21.3
chr17_-_37395460 12.35 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr4_+_76671012 12.34 ENSDART00000005585
membrane-spanning 4-domains, subfamily A, member 17a.2
chr15_-_34892664 12.17 ENSDART00000153787
ENSDART00000099721
ring finger protein 183
chr16_-_42004544 11.69 ENSDART00000034544
caspase a
chr5_+_30741730 11.67 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr13_-_25774183 11.49 ENSDART00000046981
PDZ and LIM domain 1 (elfin)
chr7_+_73670137 11.47 ENSDART00000050357
bloodthirsty-related gene family, member 12
chr8_+_52479026 11.46 ENSDART00000162885
Danio rerio gamma-glutamyl hydrolase (LOC553228), mRNA.
chr22_+_22004082 10.94 ENSDART00000148375
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2
chr3_-_26204867 10.93 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr4_-_77979432 10.89 ENSDART00000049170
zgc:85975
chr14_-_25956804 10.66 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr12_-_4540564 10.66 ENSDART00000106566

chr21_-_32436679 10.65 ENSDART00000076974
glutamine-fructose-6-phosphate transaminase 2
chr17_+_51743908 10.54 ENSDART00000149039
ENSDART00000148869
ornithine decarboxylase 1
chr6_-_35401282 10.46 ENSDART00000127612
regulator of G protein signaling 5a
chr14_+_33329420 10.26 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr12_+_46634736 10.25 ENSDART00000008009
tripartite motif containing 16
chr3_-_32590164 10.25 ENSDART00000151151
tetraspanin 4b
chr16_-_6424816 10.22 ENSDART00000164864
ENSDART00000141860
membrane bound O-acyltransferase domain containing 1
chr22_-_10502780 10.16 ENSDART00000136961
extracellular matrix protein 2, female organ and adipocyte specific
chr25_+_30196039 10.05 ENSDART00000005299
hydroxysteroid (17-beta) dehydrogenase 12a
chr3_-_53092509 10.02 ENSDART00000062081
lysophosphatidic acid receptor 2a
chr16_+_51180938 10.02 ENSDART00000169022
high mobility group nucleosomal binding domain 2
chr7_+_19835569 10.01 ENSDART00000149812
ovo-like zinc finger 1a
chr5_+_58665648 9.91 ENSDART00000167481
zgc:194948
chr20_+_16881883 9.71 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr12_-_16990896 9.27 ENSDART00000152402
interferon-induced protein with tetratricopeptide repeats 12
chr9_-_3400727 9.17 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr6_-_24103666 9.12 ENSDART00000164915
scinderin like a
chr12_+_38929663 8.94 ENSDART00000156334
si:dkey-239b22.1
chr15_+_12429206 8.84 ENSDART00000168997
transmembrane protease, serine 4a
chr12_+_38878830 8.67 ENSDART00000156926
si:ch211-39f2.3
chr7_+_57088920 8.54 ENSDART00000024076
secretory carrier membrane protein 2, like
chr13_+_669177 8.50 ENSDART00000190085

chr21_+_19648814 8.40 ENSDART00000048581
fibroblast growth factor 10a
chr5_-_23855447 8.25 ENSDART00000051541
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
chr15_+_41919484 8.12 ENSDART00000099821
ENSDART00000146246
NACHT, LRR and PYD domains-containing protein 16
chr21_-_13668358 8.11 ENSDART00000180323
patatin-like phospholipase domain containing 7a
chr21_-_42831033 7.96 ENSDART00000160998
serine/threonine kinase 10
chr22_+_9806867 7.95 ENSDART00000137182
ENSDART00000106103
si:ch211-236g6.1
chr21_+_25625026 7.92 ENSDART00000134678
ovo-like zinc finger 1b
chr3_+_6469754 7.88 ENSDART00000185809
nucleoporin 85
chr22_-_3299355 7.80 ENSDART00000190993
si:zfos-943e10.1
chr9_-_11550711 7.55 ENSDART00000093343
FEV (ETS oncogene family)
chr6_+_23810529 7.54 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr8_-_46457233 7.54 ENSDART00000113214
sulfotransferase family 1, cytosolic sulfotransferase 7
chr18_+_27571448 7.53 ENSDART00000147886
CD82 molecule b
chr13_-_40411908 7.53 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr5_+_36599107 7.28 ENSDART00000097677
ENSDART00000138147
mitochondrial calcium uptake 2
chr18_-_40773413 7.26 ENSDART00000133797
vasodilator stimulated phosphoprotein b
chr22_+_19552987 7.21 ENSDART00000105315
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr5_+_20319519 7.04 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr16_+_29509133 6.99 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr14_+_33329761 6.72 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr2_-_47620806 6.70 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr1_-_21321482 6.63 ENSDART00000054440
transmembrane protein 144a
chr8_-_28349859 6.58 ENSDART00000062671
tubulin, alpha 8 like
chr5_+_21891305 6.52 ENSDART00000136788
si:ch73-92i20.1
chr22_-_15587360 6.45 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr15_+_13984879 6.44 ENSDART00000159438
zgc:162730
chr1_-_56556326 6.25 ENSDART00000188760

chr2_-_43151358 6.20 ENSDART00000061170
ENSDART00000056161
finTRIM family, member 15
chr16_+_29586004 6.08 ENSDART00000149520
MCL1, BCL2 family apoptosis regulator b
chr16_+_29586468 6.08 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr20_-_39367895 5.97 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
PDZ binding kinase
chr23_-_26252103 5.92 ENSDART00000160873
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr3_+_5083407 5.68 ENSDART00000146883
si:ch73-338o16.4
chr8_-_32805214 5.63 ENSDART00000131597
zgc:194839
chr7_+_57089354 5.63 ENSDART00000140702
secretory carrier membrane protein 2, like
chr13_+_24671481 5.42 ENSDART00000001678
ADAM metallopeptidase domain 8a
chr10_+_39084354 5.40 ENSDART00000158245
si:ch73-1a9.3
chr13_+_18533005 5.32 ENSDART00000136024
finTRIM family, member 14-like
chr14_+_7048930 5.28 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr10_+_44692272 5.25 ENSDART00000157458
ubiquitin C
chr23_+_7471072 5.22 ENSDART00000135551
si:ch211-200e2.1
chr22_-_4778018 5.19 ENSDART00000143968
si:ch73-256j6.5
chr10_+_36458563 5.11 ENSDART00000077008
arachidonate 5-lipoxygenase-activating protein
chr22_-_3299100 5.03 ENSDART00000160305
si:zfos-943e10.1
chr12_+_30234209 5.02 ENSDART00000102081
actin filament associated protein 1-like 2
chr7_+_57725708 5.01 ENSDART00000056466
ENSDART00000142259
ENSDART00000166198
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr4_+_78058635 4.94 ENSDART00000162631
ENSDART00000191619

chr4_-_77636185 4.89 ENSDART00000152915
ENSDART00000131964
si:dkey-61p9.9
chr7_-_52417777 4.85 ENSDART00000110265
myocardial zonula adherens protein
chr5_+_50953240 4.80 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr22_-_17631675 4.74 ENSDART00000132565
histocompatibility (minor) HA-1 b
chr15_-_28904371 4.74 ENSDART00000155154
echinoderm microtubule associated protein like 2
chr6_+_58915889 4.73 ENSDART00000083628
DNA-damage-inducible transcript 3
chr2_+_44571200 4.72 ENSDART00000098132
kelch-like family member 24a
chr6_+_13506841 4.70 ENSDART00000032331
GDP-mannose pyrophosphorylase Ab
chr8_-_13029297 4.65 ENSDART00000144305
DENN/MADD domain containing 2Da
chr3_-_34528306 4.64 ENSDART00000023039
septin 9a
chr14_-_31087830 4.59 ENSDART00000002250
heparan sulfate 6-O-sulfotransferase 2
chr13_-_36798204 4.58 ENSDART00000012357
salvador family WW domain containing protein 1
chr25_+_10923100 4.49 ENSDART00000157055
si:ch211-147g22.7
chr16_+_5597600 4.46 ENSDART00000017307
zgc:91890
chr13_+_31321297 4.45 ENSDART00000143308
anthrax toxin receptor 1d
chr3_-_29977495 4.41 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr23_-_3511630 4.38 ENSDART00000019667
ring finger protein 114
chr12_+_30233977 4.31 ENSDART00000188135
actin filament associated protein 1-like 2
chr8_+_52377516 4.26 ENSDART00000115398
AT rich interactive domain 5A (MRF1-like)
chr17_-_43677471 4.23 ENSDART00000137015
early growth response 2a
chr5_+_72152813 4.18 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr4_-_26035770 4.11 ENSDART00000124514
ubiquitin specific peptidase 44
chr7_-_24193051 4.10 ENSDART00000169737
ENSDART00000171085
si:ch211-216p19.6
chr12_+_22657925 4.10 ENSDART00000153048
si:dkey-219e21.4
chr17_+_15213496 4.08 ENSDART00000058351
ENSDART00000131663
glucosamine-phosphate N-acetyltransferase 1
chr7_-_56606752 4.08 ENSDART00000138714
sulfotransferase family 5A, member 1
chr5_+_43807003 4.06 ENSDART00000097625
zgc:158640
chr19_-_2861444 4.00 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr6_+_41452979 3.99 ENSDART00000007353
WD repeat domain 82
chr21_-_14310159 3.98 ENSDART00000155097
si:ch211-196i2.1
chr6_-_48094342 3.90 ENSDART00000137458
solute carrier family 2 (facilitated glucose transporter), member 1b
chr3_-_36846496 3.88 ENSDART00000055237
receptor (G protein-coupled) activity modifying protein 2
chr4_+_6032640 3.85 ENSDART00000157487
transcription factor EC
chr1_-_46401385 3.80 ENSDART00000150029
ATPase phospholipid transporting 11A
chr5_-_67750907 3.80 ENSDART00000172097
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr20_-_16852 3.79 ENSDART00000129277
ENSDART00000148717
zgc:174972
chr10_-_1523253 3.79 ENSDART00000179510
ENSDART00000176548
ENSDART00000180368
ENSDART00000185270
WD repeat domain 70
chr15_-_34865952 3.72 ENSDART00000186868
SH3-binding domain protein 5-like, a
chr21_-_30166097 3.71 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr7_-_54430505 3.69 ENSDART00000167905
anoctamin 1, calcium activated chloride channel
chr14_+_17376940 3.68 ENSDART00000054590
ENSDART00000010148
spondin 2b, extracellular matrix protein
chr14_-_31489410 3.64 ENSDART00000018347
calcium binding protein 39, like 1
chr19_+_31576849 3.64 ENSDART00000134107
ENSDART00000088401
acyl-CoA thioesterase 13
chr8_+_25342896 3.57 ENSDART00000129032

chr18_+_47313715 3.53 ENSDART00000138806
BARX homeobox 2
chr7_+_19483277 3.52 ENSDART00000173750
si:ch211-212k18.7
chr7_+_66739166 3.45 ENSDART00000154634
murine retrovirus integration site 1 homolog
chr21_-_8085635 3.44 ENSDART00000082790
si:dkey-163m14.2
chr4_-_20222182 3.44 ENSDART00000132464
gamma-secretase activating protein
chr15_-_5901514 3.43 ENSDART00000155252
si:ch73-281n10.2
chr22_-_16275236 3.40 ENSDART00000149051
cell division cycle 14Ab
chr8_+_27555314 3.38 ENSDART00000135568
ENSDART00000016696
ras homolog family member Cb
chr19_+_23308419 3.35 ENSDART00000141558
immunity-related GTPase family, f2
chr15_-_452347 3.34 ENSDART00000115233
V-set and transmembrane domain containing 5
chr10_+_29204581 3.31 ENSDART00000148503
phosphatidylinositol binding clathrin assembly protein a
chr2_-_42035250 3.29 ENSDART00000056460
ENSDART00000140788
guanylate binding protein 1
chr12_-_34035364 3.29 ENSDART00000087065
TIMP metallopeptidase inhibitor 2a
chr11_+_25112269 3.27 ENSDART00000147546
ndrg family member 3a
chr6_-_49526510 3.26 ENSDART00000128025
ribosomal protein S26, like
chr20_-_25631256 3.25 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr8_-_29658171 3.25 ENSDART00000147755
macrophage expressed 1, tandem duplicate 3
chr8_-_52715911 3.21 ENSDART00000168241
tubulin, beta 2b
chr11_+_25111846 3.18 ENSDART00000128705
ENSDART00000190058
ndrg family member 3a
chr21_+_15375785 3.18 ENSDART00000147666
si:dkey-11o15.8
chr12_+_48841182 3.14 ENSDART00000109315
ENSDART00000185609
ENSDART00000187217
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr2_-_7711522 3.13 ENSDART00000163175
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr8_-_11067079 3.12 ENSDART00000181986
DENN/MADD domain containing 2C
chr8_-_418997 3.09 ENSDART00000166683
protein geranylgeranyltransferase type I, beta subunit
chr4_+_18963822 3.05 ENSDART00000066975
ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr13_-_11679486 3.03 ENSDART00000108694
si:ch211-195e19.1
chr24_+_5935377 2.98 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abl-interactor 1a
chr18_+_17725410 2.97 ENSDART00000090608
ring finger and SPRY domain containing 1
chr20_+_53181017 2.96 ENSDART00000189692
ENSDART00000177109
FIG4 phosphoinositide 5-phosphatase
chr14_+_20941534 2.95 ENSDART00000185616
zgc:66433
chr3_-_26806032 2.87 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr5_-_38438613 2.86 ENSDART00000131912
phospholipase D2
chr12_-_10476448 2.82 ENSDART00000106172
Rac family small GTPase 1a
chr22_+_19640309 2.79 ENSDART00000061725
ENSDART00000140819
RGM domain family, member D
chr15_-_34668485 2.78 ENSDART00000186605
BCL2 associated athanogene 6
chr23_-_270847 2.76 ENSDART00000191867
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr14_+_45350008 2.75 ENSDART00000025749
tetratricopeptide repeat domain 9C
chr7_-_34256374 2.73 ENSDART00000075176
DIS3 like exosome 3'-5' exoribonuclease
chr13_+_18471546 2.70 ENSDART00000090712
ENSDART00000127962
storkhead box 1
chr16_-_12496632 2.68 ENSDART00000019941
solute carrier family 2 (facilitated glucose transporter), member 3b
chr9_-_10068004 2.61 ENSDART00000011922
ENSDART00000162818
speckle-type POZ protein-like a
chr12_+_27156943 2.61 ENSDART00000153030
ENSDART00000001737
src kinase associated phosphoprotein 1
chr20_-_22193190 2.60 ENSDART00000047624
transmembrane protein 165
chr15_+_1004680 2.60 ENSDART00000157310
si:dkey-77f5.8
chr13_+_33268657 2.51 ENSDART00000002095
transmembrane protein 39B

Network of associatons between targets according to the STRING database.

First level regulatory network of tfcp2+tfcp2l1+ubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.5 GO:0003156 regulation of organ formation(GO:0003156)
6.5 19.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
5.7 22.7 GO:0055107 Golgi to secretory granule transport(GO:0055107)
4.1 12.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
3.2 9.7 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
3.1 9.3 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
2.1 8.4 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
2.0 10.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
2.0 15.8 GO:1990845 adaptive thermogenesis(GO:1990845)
1.8 5.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.7 6.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
1.5 9.2 GO:0035881 amacrine cell differentiation(GO:0035881)
1.4 10.0 GO:0070285 pigment cell development(GO:0070285)
1.3 4.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
1.3 10.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.2 4.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.2 10.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
1.1 14.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.1 7.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.0 4.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.0 5.1 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
1.0 9.0 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
1.0 19.0 GO:0042574 retinal metabolic process(GO:0042574)
0.9 2.8 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.9 2.6 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.8 12.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.8 4.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.7 4.5 GO:0032218 riboflavin transport(GO:0032218)
0.7 23.2 GO:0001649 osteoblast differentiation(GO:0001649)
0.7 4.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.6 5.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 3.4 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.6 12.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 3.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 18.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.5 1.6 GO:0034214 protein hexamerization(GO:0034214)
0.5 2.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.5 3.1 GO:0001955 blood vessel maturation(GO:0001955)
0.5 4.4 GO:1901998 toxin transport(GO:1901998)
0.5 2.5 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.5 8.3 GO:0030259 lipid glycosylation(GO:0030259)
0.5 10.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.5 3.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.5 13.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 2.3 GO:0043111 replication fork arrest(GO:0043111)
0.5 10.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.4 5.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4 11.6 GO:0051923 sulfation(GO:0051923)
0.4 8.0 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.4 2.4 GO:0016572 histone phosphorylation(GO:0016572)
0.4 15.2 GO:0030199 collagen fibril organization(GO:0030199)
0.4 3.4 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.4 11.7 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.4 2.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 6.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4 2.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 3.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 1.0 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.3 3.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.3 3.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 3.0 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.3 1.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 3.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 1.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3 8.4 GO:0051014 actin filament severing(GO:0051014)
0.3 1.9 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.3 1.3 GO:2000301 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 2.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 31.6 GO:1990266 neutrophil migration(GO:1990266)
0.3 15.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 6.1 GO:0001843 neural tube closure(GO:0001843)
0.2 2.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 3.4 GO:0045116 protein neddylation(GO:0045116)
0.2 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 1.8 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.2 3.3 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2 3.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.2 6.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 5.9 GO:0090148 membrane fission(GO:0090148)
0.2 2.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 1.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 2.6 GO:0031397 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.2 17.6 GO:0031101 fin regeneration(GO:0031101)
0.2 2.9 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.2 0.6 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 18.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 4.4 GO:0042073 intraciliary transport(GO:0042073)
0.1 2.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.8 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 2.1 GO:0036065 fucosylation(GO:0036065)
0.1 0.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.4 GO:0015074 DNA integration(GO:0015074)
0.1 7.8 GO:0051607 defense response to virus(GO:0051607)
0.1 1.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 9.3 GO:0050673 epithelial cell proliferation(GO:0050673)
0.1 3.8 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.6 GO:0060021 palate development(GO:0060021)
0.1 3.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.9 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 14.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.1 1.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 2.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 8.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 2.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.3 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 2.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 17.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.7 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 3.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.1 1.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.2 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 1.5 GO:0030282 bone mineralization(GO:0030282)
0.0 1.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.9 GO:0007020 microtubule nucleation(GO:0007020)
0.0 3.5 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.0 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 2.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 3.9 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 4.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 2.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 4.4 GO:0060047 heart contraction(GO:0060047)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 13.4 GO:0006325 chromatin organization(GO:0006325)
0.0 1.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 3.6 GO:0009617 response to bacterium(GO:0009617)
0.0 2.5 GO:0001889 liver development(GO:0001889)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 2.9 GO:0072594 establishment of protein localization to organelle(GO:0072594)
0.0 6.2 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0050768 negative regulation of neurogenesis(GO:0050768)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
4.3 12.9 GO:0005592 collagen type XI trimer(GO:0005592)
2.9 11.7 GO:0061702 inflammasome complex(GO:0061702)
2.2 17.9 GO:0042613 MHC class II protein complex(GO:0042613)
1.8 5.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.4 21.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.0 3.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.7 14.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.6 3.4 GO:1902636 kinociliary basal body(GO:1902636)
0.5 6.6 GO:1990246 uniplex complex(GO:1990246)
0.5 2.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.5 2.3 GO:0031298 replication fork protection complex(GO:0031298)
0.4 2.5 GO:0070062 extracellular exosome(GO:0070062)
0.4 2.8 GO:0071818 BAT3 complex(GO:0071818)
0.4 6.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 1.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 1.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.3 41.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 3.3 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 2.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 11.5 GO:0031941 filamentous actin(GO:0031941)
0.2 28.4 GO:0016324 apical plasma membrane(GO:0016324)
0.2 4.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 2.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 11.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.4 GO:0070652 HAUS complex(GO:0070652)
0.1 4.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 5.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 5.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 29.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 6.4 GO:0005884 actin filament(GO:0005884)
0.1 9.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 7.9 GO:0030027 lamellipodium(GO:0030027)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 9.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.7 GO:0005686 U2 snRNP(GO:0005686)
0.1 4.7 GO:0072686 mitotic spindle(GO:0072686)
0.1 5.9 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 0.6 GO:0070449 elongin complex(GO:0070449)
0.1 1.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 17.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 17.7 GO:0000785 chromatin(GO:0000785)
0.1 20.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 8.5 GO:0009986 cell surface(GO:0009986)
0.0 2.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 4.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 37.5 GO:0005615 extracellular space(GO:0005615)
0.0 3.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 3.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 16.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 5.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
3.9 15.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.5 10.2 GO:0070052 collagen V binding(GO:0070052)
2.1 10.7 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
2.0 10.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.9 19.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.6 14.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.6 9.3 GO:0042169 SH2 domain binding(GO:0042169)
1.3 5.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.2 4.7 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
1.2 10.5 GO:0004586 ornithine decarboxylase activity(GO:0004586)
1.1 7.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0 3.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.9 20.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 7.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.8 11.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.8 3.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.8 21.7 GO:0015248 sterol transporter activity(GO:0015248)
0.8 4.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.7 4.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.7 7.3 GO:0005522 profilin binding(GO:0005522)
0.7 10.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 2.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.6 8.7 GO:0002020 protease binding(GO:0002020)
0.6 2.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.6 11.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.6 3.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 3.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 2.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.4 8.9 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 2.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 3.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 2.9 GO:0004630 phospholipase D activity(GO:0004630)
0.4 1.6 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.4 8.4 GO:0042056 chemoattractant activity(GO:0042056)
0.4 9.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 47.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 2.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.4 6.7 GO:0015026 coreceptor activity(GO:0015026)
0.3 7.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 5.5 GO:0031386 protein tag(GO:0031386)
0.3 7.2 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.3 10.7 GO:0005518 collagen binding(GO:0005518)
0.3 2.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 41.6 GO:0042803 protein homodimerization activity(GO:0042803)
0.3 2.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 0.8 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.3 3.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 25.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 3.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 0.9 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 2.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 6.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.2 2.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 0.7 GO:0046978 MHC class I protein binding(GO:0042288) TAP1 binding(GO:0046978)
0.2 1.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 1.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 8.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 5.2 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 4.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.2 3.1 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 3.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 14.3 GO:0019955 cytokine binding(GO:0019955)
0.1 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 7.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 2.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 3.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 19.4 GO:0005125 cytokine activity(GO:0005125)
0.1 0.6 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 0.3 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 2.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 2.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 7.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 2.5 GO:0017069 snRNA binding(GO:0017069)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 3.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0050699 WW domain binding(GO:0050699)
0.1 4.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 2.6 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 41.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 3.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 5.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 8.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.7 GO:0008134 transcription factor binding(GO:0008134)
0.0 10.8 GO:0051015 actin filament binding(GO:0051015)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 3.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 8.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 5.4 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 4.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.1 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 15.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 2.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 4.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 7.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 10.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.2 PID ATM PATHWAY ATM pathway
0.1 19.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 7.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.9 14.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.7 10.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 4.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 4.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 15.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2 3.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 2.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 3.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 4.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 2.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 3.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 3.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 2.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 10.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 2.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 3.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC