ISMARA results: tefa+tefb

Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation

Downloads

Results for tefa+tefb

Z-value: 1.25

Motif logo

Transcription factors associated with tefa+tefb

Gene Symbol	Gene ID	Gene Info
tefa NCBI UniProt	ENSDARG00000039117	TEF transcription factor, PAR bZIP family member a
tefb NCBI UniProt	ENSDARG00000098103	TEF transcription factor, PAR bZIP family member b
tefa NCBI UniProt	ENSDARG00000109532	TEF transcription factor, PAR bZIP family member a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
tefb	dr11_v1_chr3_-_5067585_5067585	0.77	1.3e-19	Click!
tefa	dr11_v1_chr12_-_19151708_19151708	0.62	2.7e-11	Click!

Activity profile of tefa+tefb motif

Sorted Z-values of tefa+tefb motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_31112436 Show fit	27.86	ENSDART00000075340	eef1a1b NCBI UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1b
chr16_+_34523515 Show fit	27.15	ENSDART00000041007	stmn1b NCBI UniProt Show fit	stathmin 1b
chr17_-_43466317 Show fit	26.37	ENSDART00000155313	hspa4l NCBI UniProt Show fit	heat shock protein 4 like
chr4_-_5302866 Show fit	25.59	ENSDART00000138590	SNAP91 (1 of many) NCBI UniProt Show fit	si:ch211-214j24.9
chr25_+_15354095 Show fit	23.79	ENSDART00000090397	kiaa1549la NCBI UniProt Show fit	KIAA1549-like a
chr3_-_46818001 Show fit	22.91	ENSDART00000166505	elavl3 NCBI UniProt Show fit	ELAV like neuron-specific RNA binding protein 3
chr16_+_46111849 Show fit	21.81	ENSDART00000172232	sv2a NCBI UniProt Show fit	synaptic vesicle glycoprotein 2A
chr17_-_20979077 Show fit	18.66	ENSDART00000006676	phyhipla NCBI UniProt Show fit	phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr10_-_24371312 Show fit	17.91	ENSDART00000149362	pitpnab NCBI UniProt Show fit	phosphatidylinositol transfer protein, alpha b
chr4_-_5302162 Show fit	17.66	ENSDART00000177099	SNAP91 (1 of many) NCBI UniProt Show fit	si:ch211-214j24.9

Showing 1 to 10 of 111 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of tefa+tefb

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	30.5	GO:0006836	neurotransmitter transport(GO:0006836)
0.4	27.9	GO:0006414	translational elongation(GO:0006414)
0.6	27.2	GO:0007019	microtubule depolymerization(GO:0007019)
0.1	25.1	GO:0050767	regulation of neurogenesis(GO:0050767)
1.1	24.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	21.2	GO:0031175	neuron projection development(GO:0031175)
0.3	17.9	GO:0015914	phospholipid transport(GO:0015914)
4.4	17.5	GO:0060074	synapse maturation(GO:0060074)
0.7	16.2	GO:0051932	synaptic transmission, GABAergic(GO:0051932)
0.4	16.1	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)

Showing 1 to 10 of 55 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	43.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	39.3	GO:0043005	neuron projection(GO:0043005)
0.1	34.2	GO:0030424	axon(GO:0030424)
0.2	25.8	GO:0014069	postsynaptic density(GO:0014069)
0.0	24.8	GO:0005829	cytosol(GO:0005829)
0.4	17.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.5	17.3	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	16.8	GO:1990904	ribonucleoprotein complex(GO:1990904)
4.0	16.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	15.0	GO:0016323	basolateral plasma membrane(GO:0016323)

Showing 1 to 10 of 23 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	50.3	GO:0015631	tubulin binding(GO:0015631)
0.1	30.6	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.6	27.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	24.8	GO:0022857	transmembrane transporter activity(GO:0022857)
1.1	24.3	GO:0005452	inorganic anion exchanger activity(GO:0005452)
2.6	17.9	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.8	17.5	GO:0019894	kinesin binding(GO:0019894)
0.3	16.1	GO:0001786	phosphatidylserine binding(GO:0001786)
2.7	16.0	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
1.0	13.7	GO:0022851	benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)

Showing 1 to 10 of 49 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	6.8	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	5.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.4	2.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	2.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Showing 1 to 6 of 6 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	11.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.5	10.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	10.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3	6.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.4	5.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	3.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	2.9	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.3	2.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	0.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes

Showing 1 to 10 of 10 entries

Results for tefa+tefb

Z-value: 1.25

Motif logo

Transcription factors associated with tefa+tefb

Activity-expression correlation:

Activity profile of tefa+tefb motif

Sorted Z-values of tefa+tefb motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of tefa+tefb

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: