PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
spic Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000012435	Spi-C transcription factor (Spi-1/PU.1 related)
spi2 Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000087438	Spi-2 proto-oncogene

Gene	Promoter	Pearson corr. coef.	P-value	Plot
spic	dr11_v1_chr4_-_17812131_17812131	0.63	1.6e-11	Click!
spi2	dr11_v1_chr4_-_17805128_17805128	0.32	1.8e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_+_20934353 Show fit	38.72	ENSDART00000052660	skap2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	src kinase associated phosphoprotein 2
chr3_+_36424055 Show fit	34.81	ENSDART00000170318	si:ch1073-443f11.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-443f11.2
chr22_+_5478353 Show fit	30.07	ENSDART00000160596	tppp Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tubulin polymerization promoting protein
chr25_+_13191391 Show fit	29.99	ENSDART00000109937	si:ch211-147m6.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-147m6.2
chr25_+_13191615 Show fit	29.18	ENSDART00000168849	si:ch211-147m6.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-147m6.2
chr21_+_27448856 Show fit	28.92	ENSDART00000100784	cfbl Links NCBI UniProt ZFIN ENSEMBL Google Show fit	complement factor b-like
chr17_-_6451801 Show fit	25.59	ENSDART00000064700	fuca2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	alpha-L-fucosidase 2
chr20_+_26880668 Show fit	25.43	ENSDART00000077769	serpinb1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr10_+_41159241 Show fit	24.72	ENSDART00000141657	anxa4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	annexin A4
chr2_+_24762567 Show fit	23.92	ENSDART00000078866	ifi30 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon, gamma-inducible protein 30
chr5_+_37087583 Show fit	23.90	ENSDART00000049900	tagln2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transgelin 2
chr18_+_31073265 Show fit	23.06	ENSDART00000023539	cyba Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome b-245, alpha polypeptide
chr12_-_30558694 Show fit	22.38	ENSDART00000153417	si:ch211-28p3.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-28p3.3
chr21_-_26114886 Show fit	21.90	ENSDART00000139320	nipal4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	NIPA-like domain containing 4
chr22_-_31020690 Show fit	21.32	ENSDART00000130604	ssuh2.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ssu-2 homolog, tandem duplicate 4
chr19_+_7045033 Show fit	21.29	ENSDART00000146579	mhc1uka Links NCBI UniProt ZFIN ENSEMBL Google Show fit	major histocompatibility complex class I UKA
chr20_+_36812368 Show fit	21.14	ENSDART00000062931	abracl Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ABRA C-terminal like
chr20_-_14054083 Show fit	20.96	ENSDART00000009549	rhag Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rh associated glycoprotein
chr23_+_17980875 Show fit	20.92	ENSDART00000163452	chia.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chitinase, acidic.6
chr23_+_17981127 Show fit	20.37	ENSDART00000012571 ENSDART00000145200	chia.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chitinase, acidic.6
chr21_-_25756119 Show fit	20.21	ENSDART00000002341	cldnc Links NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin c
chr7_-_52417777 Show fit	20.10	ENSDART00000110265	myzap Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myocardial zonula adherens protein
chr5_+_54938634 Show fit	20.10	ENSDART00000163050 ENSDART00000145765	cd180 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CD180 molecule
chr3_+_29510818 Show fit	19.92	ENSDART00000055407 ENSDART00000193743 ENSDART00000123619	rac2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rac family small GTPase 2
chr15_+_36445350 Show fit	19.88	ENSDART00000154552	si:dkey-262k9.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-262k9.2
chr7_+_49664174 Show fit	19.83	ENSDART00000137059 ENSDART00000131210	rassf7b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr20_+_16881883 Show fit	19.72	ENSDART00000130107	nfkbiaa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr3_-_32965848 Show fit	19.62	ENSDART00000050930	casp6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase 6, apoptosis-related cysteine peptidase
chr21_-_22720381 Show fit	19.52	ENSDART00000130789	c1qc Links NCBI UniProt ZFIN ENSEMBL Google Show fit	complement component 1, q subcomponent, C chain
chr20_-_34127415 Show fit	19.39	ENSDART00000010028	ptgs2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	prostaglandin-endoperoxide synthase 2b
chr24_-_27436319 Show fit	18.71	ENSDART00000171489	si:dkey-25o1.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-25o1.7
chr5_-_25583125 Show fit	18.66	ENSDART00000031665 ENSDART00000145353	anxa1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	annexin A1a
chr1_-_45347393 Show fit	18.63	ENSDART00000173024	si:ch211-243a20.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-243a20.4
chr4_-_22310956 Show fit	18.06	ENSDART00000162585	hcls1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	hematopoietic cell-specific Lyn substrate 1
chr2_-_40199780 Show fit	17.93	ENSDART00000113901	ccl34a.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 34a, duplicate 4
chr15_+_46356879 Show fit	17.88	ENSDART00000154388	wu:fb18f06 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	wu:fb18f06
chr5_-_25582721 Show fit	17.86	ENSDART00000123986	anxa1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	annexin A1a
chr9_+_24088062 Show fit	17.56	ENSDART00000126198	lrrfip1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine rich repeat (in FLII) interacting protein 1a
chr19_-_5669122 Show fit	17.40	ENSDART00000112211	si:ch211-264f5.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-264f5.2
chr7_+_32901658 Show fit	17.27	ENSDART00000115420	ano9b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	anoctamin 9b
chr1_-_55942055 Show fit	16.91	ENSDART00000142371	si:ch73-343l4.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-343l4.2
chr10_+_42358426 Show fit	16.88	ENSDART00000025691	dbnla Links NCBI UniProt ZFIN ENSEMBL Google Show fit	drebrin-like a
chr7_-_50764714 Show fit	16.88	ENSDART00000110283	iqgap1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	IQ motif containing GTPase activating protein 1
chr2_-_6482240 Show fit	16.69	ENSDART00000132623	rgs13 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of G protein signaling 13
chr17_-_43022468 Show fit	16.57	ENSDART00000002945	NPC2 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:193725
chr14_+_36886950 Show fit	16.41	ENSDART00000183719	si:ch211-132p1.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-132p1.3
chr7_+_26545911 Show fit	16.39	ENSDART00000135313	tnk1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tyrosine kinase, non-receptor, 1
chr1_-_29658721 Show fit	16.25	ENSDART00000132063	si:dkey-1h24.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-1h24.6
chr9_+_21165017 Show fit	16.13	ENSDART00000145933 ENSDART00000142985	si:rp71-68n21.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:rp71-68n21.9
chr14_-_40797117 Show fit	16.05	ENSDART00000122369	elf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like ETS transcription factor 1
chr1_-_25177086 Show fit	16.03	ENSDART00000144711 ENSDART00000177225	tmem154 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 154
chr21_+_30937690 Show fit	15.84	ENSDART00000022562	rhogb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ras homolog family member Gb
chr10_-_7785930 Show fit	15.81	ENSDART00000043961 ENSDART00000111058	mpx Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myeloid-specific peroxidase
chr1_-_9228007 Show fit	15.70	ENSDART00000147277 ENSDART00000135219	gng13a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein (G protein), gamma 13a
chr8_-_2153147 Show fit	15.40	ENSDART00000124093	si:dkeyp-117b11.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-117b11.1
chr10_+_35422802 Show fit	15.21	ENSDART00000147303	hhla2a.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	HERV-H LTR-associating 2a, tandem duplicate 1
chr17_+_27456804 Show fit	15.16	ENSDART00000017756 ENSDART00000181461 ENSDART00000180178	ctsl.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin L.1
chr5_-_51166025 Show fit	15.03	ENSDART00000097471	card9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase recruitment domain family, member 9
chr21_-_17956739 Show fit	14.98	ENSDART00000148154	stx2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	syntaxin 2a
chr11_+_29975830 Show fit	14.88	ENSDART00000148929	si:ch73-226l13.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-226l13.2
chr20_+_10498986 Show fit	14.81	ENSDART00000064114	zgc:100997 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:100997
chr11_+_29965822 Show fit	14.62	ENSDART00000127049	il1fma Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin-1 family member A
chr1_+_12394205 Show fit	14.59	ENSDART00000138622 ENSDART00000136421 ENSDART00000139440 ENSDART00000184296 ENSDART00000008127	zgc:77739 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:77739
chr15_-_2652640 Show fit	14.57	ENSDART00000146094	cldnf Links NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin f
chr16_+_29514473 Show fit	14.48	ENSDART00000034102	ctss2.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin S, ortholog 2, tandem duplicate 2
chr24_+_264839 Show fit	14.38	ENSDART00000066872	ccr12b.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) receptor 12b, tandem duplicate 2
chr7_-_26049282 Show fit	14.31	ENSDART00000136389 ENSDART00000101124	rnaseka Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease, RNase K a
chr21_+_19347655 Show fit	14.22	ENSDART00000093155	hpse Links NCBI UniProt ZFIN ENSEMBL Google Show fit	heparanase
chr8_-_29713595 Show fit	14.18	ENSDART00000131988 ENSDART00000077637	mpeg1.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	macrophage expressed 1, tandem duplicate 1
chr4_-_5240128 Show fit	13.98	ENSDART00000144048	ada2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adenosine deaminase 2b
chr3_-_32603191 Show fit	13.90	ENSDART00000150997	si:ch73-248e21.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-248e21.7
chr7_+_26545502 Show fit	13.78	ENSDART00000140528	tnk1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tyrosine kinase, non-receptor, 1
chr2_-_13268556 Show fit	13.76	ENSDART00000127693 ENSDART00000079757	vps4b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr5_+_27421639 Show fit	13.73	ENSDART00000146285	cyb561a3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome b561 family, member A3a
chr1_-_16665044 Show fit	13.70	ENSDART00000040434	asah1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	N-acylsphingosine amidohydrolase (acid ceramidase) 1b
chr5_-_61445697 Show fit	13.70	ENSDART00000050898	ncf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	neutrophil cytosolic factor 1
chr18_+_13182528 Show fit	13.68	ENSDART00000166298	zgc:56622 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:56622
chr16_-_41488023 Show fit	13.63	ENSDART00000169312	cmtm6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CKLF-like MARVEL transmembrane domain containing 6
chr23_+_39089574 Show fit	13.46	ENSDART00000164711	nfatc2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of activated T cells 2a
chr22_-_15577060 Show fit	13.37	ENSDART00000176291	hsh2d Links NCBI UniProt ZFIN ENSEMBL Google Show fit	hematopoietic SH2 domain containing
chr6_+_112579 Show fit	13.32	ENSDART00000034505	ap1m2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adaptor-related protein complex 1, mu 2 subunit
chr16_+_38277339 Show fit	13.27	ENSDART00000085143	bnipl Links NCBI UniProt ZFIN ENSEMBL Google Show fit	BCL2 interacting protein like
chr6_-_14010554 Show fit	13.26	ENSDART00000004656	zgc:92027 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92027
chr15_+_5086338 Show fit	13.25	ENSDART00000155402	mxf Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myxovirus (influenza virus) resistance F
chr17_+_33415319 Show fit	13.17	ENSDART00000140805 ENSDART00000025501 ENSDART00000146447	snap23.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptosomal-associated protein 23.1
chr8_-_50482781 Show fit	13.12	ENSDART00000056361	ido1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	indoleamine 2,3-dioxygenase 1
chr6_+_49095646 Show fit	13.11	ENSDART00000103385	slc25a55a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25, member 55a
chr22_+_5687615 Show fit	13.07	ENSDART00000133241 ENSDART00000019854 ENSDART00000138102	dnase1l4.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	deoxyribonuclease 1 like 4, tandem duplicate 2
chr21_-_38853737 Show fit	13.01	ENSDART00000184100	tlr22 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	toll-like receptor 22
chr9_-_28687484 Show fit	12.95	ENSDART00000136537	si:ch73-7i4.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-7i4.3
chr4_-_18954001 Show fit	12.90	ENSDART00000144814	si:dkey-31f5.8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-31f5.8
chr5_+_22510639 Show fit	12.87	ENSDART00000080919	rpl36a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L36A
chr10_-_15128771 Show fit	12.86	ENSDART00000101261	spp1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	secreted phosphoprotein 1
chr19_-_18626515 Show fit	12.83	ENSDART00000160624	rps18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S18
chr17_+_30843881 Show fit	12.74	ENSDART00000149600 ENSDART00000148547	tpp1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tripeptidyl peptidase I
chr16_+_31542645 Show fit	12.69	ENSDART00000163724	SLA (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Src like adaptor
chr10_+_13209580 Show fit	12.66	ENSDART00000000887 ENSDART00000136932	rassf6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Ras association (RalGDS/AF-6) domain family 6
chr3_-_40528333 Show fit	12.51	ENSDART00000193047	actb2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	actin, beta 2
chr22_+_36719821 Show fit	12.48	ENSDART00000149093	TRIM35 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-324l1.1
chr21_-_35534401 Show fit	12.47	ENSDART00000112308	si:dkeyp-23e4.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-23e4.3
chr23_-_40766518 Show fit	12.44	ENSDART00000127420	si:dkeyp-27c8.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-27c8.2
chr4_-_22311610 Show fit	12.44	ENSDART00000137814	hcls1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	hematopoietic cell-specific Lyn substrate 1
chr4_-_5239904 Show fit	12.42	ENSDART00000190664	ada2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adenosine deaminase 2b
chr19_+_348729 Show fit	12.37	ENSDART00000114284	mcl1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	MCL1, BCL2 family apoptosis regulator a
chr19_-_3821678 Show fit	12.35	ENSDART00000169639	si:dkey-206d17.12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-206d17.12
chr3_+_32099507 Show fit	12.28	ENSDART00000044238	zgc:92066 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92066
chr13_-_36050303 Show fit	12.20	ENSDART00000134955 ENSDART00000139087	lgmn Links NCBI UniProt ZFIN ENSEMBL Google Show fit	legumain
chr24_-_26479841 Show fit	12.11	ENSDART00000079984	rpl22l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L22-like 1
chr19_-_40175800 Show fit	12.11	ENSDART00000102904	illr4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	immune-related, lectin-like receptor 4
chr20_-_35470891 Show fit	12.08	ENSDART00000152993 ENSDART00000016090	pla2g7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr15_-_18209672 Show fit	12.03	ENSDART00000141508 ENSDART00000136280	btr16 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 16
chr19_+_4038589 Show fit	12.03	ENSDART00000169271	btr23 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 23
chr2_+_30281444 Show fit	12.01	ENSDART00000172756	si:dkey-82k12.13 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-82k12.13
chr21_+_33454147 Show fit	11.94	ENSDART00000053208	rps14 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S14
chr13_+_23623346 Show fit	11.88	ENSDART00000057619	il22ra2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 22 receptor, alpha 2
chr21_+_28747069 Show fit	11.87	ENSDART00000014058	zgc:100829 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:100829
chr1_-_8980665 Show fit	11.73	ENSDART00000148182	si:ch73-191k20.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-191k20.3
chr17_+_33415542 Show fit	11.55	ENSDART00000183169	snap23.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptosomal-associated protein 23.1
chr18_+_36631923 Show fit	11.49	ENSDART00000098980	znf296 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 296
chr17_-_27382826 Show fit	11.31	ENSDART00000186657 ENSDART00000155986 ENSDART00000191060 ENSDART00000077608	si:ch1073-358c10.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-358c10.1
chr14_+_10505464 Show fit	11.29	ENSDART00000091224	p2ry10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	P2Y receptor family member 10
chr12_+_10134366 Show fit	11.27	ENSDART00000127343	smarcd2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr14_-_16810401 Show fit	11.26	ENSDART00000158396 ENSDART00000170758	tcirg1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr5_+_24086227 Show fit	11.19	ENSDART00000051549 ENSDART00000177458 ENSDART00000135934	tp53 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor protein p53
chr3_-_16719244 Show fit	11.17	ENSDART00000055859	pold1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (DNA directed), delta 1, catalytic subunit
chr19_+_18758014 Show fit	11.17	ENSDART00000158935	clic1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chloride intracellular channel 1
chr2_-_30182353 Show fit	11.09	ENSDART00000019149	rpl7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L7
chr10_+_24690534 Show fit	11.08	ENSDART00000079549	tpte Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane phosphatase with tensin homology
chr6_+_39290777 Show fit	11.03	ENSDART00000155700	si:dkey-195m11.11 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-195m11.11
chr8_-_30242706 Show fit	11.02	ENSDART00000139864 ENSDART00000143809	zgc:162939 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162939
chr10_-_33557299 Show fit	10.93	ENSDART00000099732	il2rga Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 2 receptor, gamma a
chr20_+_18994059 Show fit	10.85	ENSDART00000152380	tdh Links NCBI UniProt ZFIN ENSEMBL Google Show fit	L-threonine dehydrogenase
chr3_-_34561624 Show fit	10.81	ENSDART00000129313	sept9a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	septin 9a
chr14_-_706345 Show fit	10.79	ENSDART00000166632	si:zfos-741a10.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-741a10.3
chr16_-_31756859 Show fit	10.75	ENSDART00000149170 ENSDART00000126617 ENSDART00000182722	ptpn6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine phosphatase, non-receptor type 6
chr5_+_66312359 Show fit	10.64	ENSDART00000137534	malt1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	MALT paracaspase 1
chr17_-_29213710 Show fit	10.62	ENSDART00000076481	ehd4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	EH-domain containing 4
chr16_-_46605160 Show fit	10.56	ENSDART00000189070 ENSDART00000181194	tmem176l.3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 176l.3a
chr16_-_22303130 Show fit	10.47	ENSDART00000142181	si:dkey-92i15.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-92i15.4
chr8_-_3312384 Show fit	10.43	ENSDART00000035965	fut9b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fucosyltransferase 9b
chr5_-_23909934 Show fit	10.43	ENSDART00000142516	si:ch211-135f11.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-135f11.1
chr16_+_21867161 Show fit	10.33	ENSDART00000060424	zmp:0000000608 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zmp:0000000608
chr13_-_12581388 Show fit	10.29	ENSDART00000079655	enpep Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamyl aminopeptidase
chr6_+_13506841 Show fit	10.24	ENSDART00000032331	gmppab Links NCBI UniProt ZFIN ENSEMBL Google Show fit	GDP-mannose pyrophosphorylase Ab
chr15_-_14064302 Show fit	10.21	ENSDART00000156384	BX927244.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr1_+_57787642 Show fit	10.21	ENSDART00000127091	si:dkey-1c7.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-1c7.2
chr5_-_24029228 Show fit	10.15	ENSDART00000051546	rps6ka3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S6 kinase a, polypeptide 3a
chr14_+_3038473 Show fit	10.13	ENSDART00000026021 ENSDART00000150000	cd74a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CD74 molecule, major histocompatibility complex, class II invariant chain a
chr22_+_9806867 Show fit	10.09	ENSDART00000137182 ENSDART00000106103	si:ch211-236g6.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-236g6.1
chr3_+_18579806 Show fit	10.08	ENSDART00000180967 ENSDART00000089765	arhgap17b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 17b
chr19_-_11431278 Show fit	10.06	ENSDART00000109889	hsbp1l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock factor binding protein 1 like 1
chr2_-_51500957 Show fit	9.99	ENSDART00000172481	pigrl3.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	polymeric immunoglobulin receptor-like 3.5
chr4_+_76745015 Show fit	9.94	ENSDART00000155883	ms4a17a.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane-spanning 4-domains, subfamily A, member 17A.10
chr4_+_76637548 Show fit	9.93	ENSDART00000133799	ms4a17a.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane-spanning 4-domains, subfamily A, member 17A.9
chr1_+_52735484 Show fit	9.92	ENSDART00000182076	CABZ01021532.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr9_-_704667 Show fit	9.92	ENSDART00000147092	cflarb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CASP8 and FADD-like apoptosis regulator b
chr19_-_18626952 Show fit	9.90	ENSDART00000168004 ENSDART00000162034 ENSDART00000165486 ENSDART00000167971	rps18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S18
chr5_+_50953240 Show fit	9.86	ENSDART00000148501 ENSDART00000149892 ENSDART00000190312	col4a3bpa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr14_-_16807206 Show fit	9.83	ENSDART00000157957	tcirg1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr23_+_24989387 Show fit	9.81	ENSDART00000172299 ENSDART00000145307	arhgap4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 4a
chr25_+_5068442 Show fit	9.79	ENSDART00000097522	parvg Links NCBI UniProt ZFIN ENSEMBL Google Show fit	parvin, gamma
chr25_-_34280080 Show fit	9.77	ENSDART00000085251	gcnt3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glucosaminyl (N-acetyl) transferase 3, mucin type
chr21_-_7035599 Show fit	9.71	ENSDART00000139777	si:ch211-93g21.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-93g21.1
chr1_+_57774454 Show fit	9.63	ENSDART00000152507	si:dkey-1c7.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-1c7.2
chr18_+_14684115 Show fit	9.63	ENSDART00000108469	spata2l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	spermatogenesis associated 2-like
chr22_-_4769140 Show fit	9.59	ENSDART00000165235	calr3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calreticulin 3a
chr14_-_11529311 Show fit	9.57	ENSDART00000127208	si:ch211-153b23.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-153b23.7
chr3_-_30941362 Show fit	9.56	ENSDART00000076830	coro1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	coronin, actin binding protein, 1A
chr11_-_27953135 Show fit	9.55	ENSDART00000168338	ece1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin converting enzyme 1
chr18_+_18863167 Show fit	9.45	ENSDART00000091094	pllp Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plasmolipin
chr21_+_19844195 Show fit	9.41	ENSDART00000065674 ENSDART00000157188	fybb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	FYN binding protein b
chr16_-_41487589 Show fit	9.37	ENSDART00000188115	cmtm6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CKLF-like MARVEL transmembrane domain containing 6
chr16_-_17586883 Show fit	9.36	ENSDART00000017142	m6pr Links NCBI UniProt ZFIN ENSEMBL Google Show fit	mannose-6-phosphate receptor (cation dependent)
chr7_-_38659477 Show fit	9.34	ENSDART00000138071	npsn Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nephrosin
chr13_+_31716820 Show fit	9.29	ENSDART00000034745	prkcha Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein kinase C, eta, a
chr23_-_29394505 Show fit	9.25	ENSDART00000017728	pgd Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphogluconate dehydrogenase
chr20_+_18994465 Show fit	9.24	ENSDART00000152778	tdh Links NCBI UniProt ZFIN ENSEMBL Google Show fit	L-threonine dehydrogenase
chr4_-_25812329 Show fit	9.23	ENSDART00000146658	tmcc3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane and coiled-coil domain family 3
chr25_+_13205878 Show fit	9.18	ENSDART00000162319 ENSDART00000162283	si:ch211-147m6.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-147m6.2
chr2_+_36646451 Show fit	9.11	ENSDART00000039174	klhl6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	kelch-like family member 6
chr12_+_48815988 Show fit	9.01	ENSDART00000149089	anxa11b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	annexin A11b
chr20_+_2039518 Show fit	8.98	ENSDART00000043157	CABZ01088134.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr16_-_46619967 Show fit	8.91	ENSDART00000158341	tmem176l.3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 176l.3a
chr15_-_36533322 Show fit	8.81	ENSDART00000156466 ENSDART00000121755	si:dkey-262k9.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-262k9.4
chr2_-_51507540 Show fit	8.77	ENSDART00000166605 ENSDART00000161093	pigrl2.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	polymeric immunoglobulin receptor-like 2.3
chr16_-_17699111 Show fit	8.76	ENSDART00000108581	si:dkey-17m8.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-17m8.1
chr23_+_20803270 Show fit	8.74	ENSDART00000097381	zgc:154075 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:154075
chr6_+_52212927 Show fit	8.69	ENSDART00000143458	ywhaba Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr19_+_40350468 Show fit	8.68	ENSDART00000087444	hepacam2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	HEPACAM family member 2
chr16_-_21888047 Show fit	8.60	ENSDART00000162282 ENSDART00000124099	dicp3.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	diverse immunoglobulin domain-containing protein 3.3
chr5_-_68876211 Show fit	8.56	ENSDART00000097254	sftpbb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	surfactant protein Bb
chr7_+_19502744 Show fit	8.54	ENSDART00000171258 ENSDART00000173691	si:ch211-212k18.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k18.9
chr19_-_31765615 Show fit	8.51	ENSDART00000103636	si:dkeyp-120h9.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-120h9.1
chr3_+_43826018 Show fit	8.51	ENSDART00000166197 ENSDART00000165145	litaf Links NCBI UniProt ZFIN ENSEMBL Google Show fit	lipopolysaccharide-induced TNF factor
chr9_+_21165484 Show fit	8.50	ENSDART00000177286	si:rp71-68n21.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:rp71-68n21.9
chr5_-_26879302 Show fit	8.47	ENSDART00000098571 ENSDART00000139086	zgc:64051 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:64051
chr8_+_45361775 Show fit	8.45	ENSDART00000015193	chmp4bb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	charged multivesicular body protein 4Bb
chr17_-_24587686 Show fit	8.45	ENSDART00000143084	aftphb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	aftiphilin b
chr11_+_34921492 Show fit	8.42	ENSDART00000128070	gnai2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr21_+_28747236 Show fit	8.40	ENSDART00000137874	zgc:100829 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:100829

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.6	19.7	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
6.1	36.5	GO:2001279	neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
5.6	33.7	GO:0006004	fucose metabolic process(GO:0006004)
5.3	26.4	GO:0046103	adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
5.2	21.0	GO:0015840	urea transport(GO:0015840)
5.1	10.1	GO:0002828	regulation of type 2 immune response(GO:0002828)
4.8	19.4	GO:0019371	cyclooxygenase pathway(GO:0019371)
4.6	13.9	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
4.6	13.7	GO:0097264	self proteolysis(GO:0097264)
4.0	19.9	GO:2000391	neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
3.8	41.3	GO:0006032	chitin catabolic process(GO:0006032)
3.7	11.2	GO:0010525	regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
3.7	7.4	GO:2000108	positive regulation of leukocyte apoptotic process(GO:2000108)
3.4	13.7	GO:0045730	respiratory burst(GO:0045730)
3.4	16.9	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
3.3	23.1	GO:0042554	superoxide anion generation(GO:0042554)
3.1	12.4	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
3.0	12.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
2.9	11.5	GO:2000171	negative regulation of dendrite development(GO:2000171)
2.8	8.4	GO:0009838	abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
2.8	11.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
2.7	8.2	GO:2000471	regulation of hematopoietic stem cell migration(GO:2000471)
2.5	20.1	GO:0006566	threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
2.4	24.2	GO:0061588	calcium activated phospholipid scrambling(GO:0061588)
2.4	11.8	GO:2000561	negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
2.3	7.0	GO:0019323	pentose catabolic process(GO:0019323)
2.1	10.6	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
2.0	10.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
2.0	12.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
2.0	11.7	GO:0006013	mannose metabolic process(GO:0006013)
1.9	7.8	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.9	5.7	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
1.8	20.1	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
1.8	5.3	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
1.7	5.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
1.7	8.5	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
1.7	34.0	GO:0035723	interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
1.6	13.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
1.6	4.9	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
1.5	21.1	GO:0051452	vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
1.5	5.8	GO:0010039	response to iron ion(GO:0010039)
1.4	15.7	GO:0050909	sensory perception of taste(GO:0050909)
1.3	5.3	GO:0048940	anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
1.3	13.1	GO:0015813	acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
1.3	9.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
1.3	21.9	GO:0015693	magnesium ion transport(GO:0015693)
1.3	11.3	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
1.2	7.5	GO:0032367	intracellular cholesterol transport(GO:0032367)
1.2	51.9	GO:0048247	lymphocyte chemotaxis(GO:0048247)
1.2	8.6	GO:0060855	venous endothelial cell migration involved in lymph vessel development(GO:0060855)
1.2	15.8	GO:2000377	regulation of reactive oxygen species metabolic process(GO:2000377)
1.2	4.7	GO:0052746	inositol phosphorylation(GO:0052746)
1.2	17.5	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
1.1	4.6	GO:0032534	regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
1.1	10.1	GO:0034605	cellular response to heat(GO:0034605)
1.1	39.7	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
1.1	4.2	GO:0060043	regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
1.1	29.4	GO:0016601	Rac protein signal transduction(GO:0016601)
1.0	6.9	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.0	18.2	GO:0098884	postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.9	3.8	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.9	9.2	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.9	4.5	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.9	2.7	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.9	31.8	GO:0042113	B cell activation(GO:0042113)
0.9	2.6	GO:0001779	natural killer cell differentiation(GO:0001779)
0.9	4.3	GO:0010332	response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.9	5.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.9	9.4	GO:0006622	protein targeting to lysosome(GO:0006622)
0.8	5.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.8	8.4	GO:0035588	adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.8	4.2	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.8	12.4	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.8	3.3	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.8	4.8	GO:0032218	riboflavin transport(GO:0032218)
0.8	7.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.8	4.7	GO:1990108	protein linear deubiquitination(GO:1990108)
0.8	13.1	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.8	19.6	GO:0032944	regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.7	7.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.7	5.7	GO:0044528	regulation of mitochondrial mRNA stability(GO:0044528)
0.7	6.4	GO:0006167	AMP biosynthetic process(GO:0006167)
0.7	7.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.7	2.8	GO:0045475	locomotor rhythm(GO:0045475)
0.7	6.7	GO:0031125	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) rRNA 3'-end processing(GO:0031125)
0.7	6.6	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.7	10.5	GO:0050930	regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.6	9.5	GO:0016486	peptide hormone processing(GO:0016486)
0.6	6.9	GO:0006797	polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.6	4.4	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.6	3.1	GO:0071939	vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.6	5.6	GO:2001239	histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.6	3.7	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6	3.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.6	1.8	GO:2000812	regulation of barbed-end actin filament capping(GO:2000812)
0.6	3.0	GO:0030329	prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.6	7.5	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.6	17.2	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.6	11.9	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.6	14.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.6	4.5	GO:0072422	signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.6	55.9	GO:0006956	complement activation(GO:0006956)
0.6	5.1	GO:0042987	beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.5	4.9	GO:0002688	regulation of leukocyte chemotaxis(GO:0002688)
0.5	2.2	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.5	3.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.5	29.2	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.5	2.7	GO:0015740	C4-dicarboxylate transport(GO:0015740)
0.5	2.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.5	6.3	GO:0070527	platelet aggregation(GO:0070527)
0.5	7.7	GO:0030041	actin filament polymerization(GO:0030041)
0.5	23.5	GO:0042742	defense response to bacterium(GO:0042742)
0.5	2.5	GO:0070189	kynurenine metabolic process(GO:0070189)
0.5	22.5	GO:0032456	endocytic recycling(GO:0032456)
0.5	6.5	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.5	2.0	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5	2.0	GO:0048308	organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.5	3.9	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.5	7.3	GO:0035108	limb morphogenesis(GO:0035108)
0.5	2.9	GO:0060347	trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.5	13.8	GO:0042476	odontogenesis(GO:0042476)
0.5	8.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5	21.4	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.5	2.3	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.5	1.4	GO:0031590	wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.4	7.8	GO:0043114	regulation of vascular permeability(GO:0043114)
0.4	5.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.4	2.5	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.4	8.8	GO:0043507	activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.4	7.0	GO:0019433	triglyceride catabolic process(GO:0019433)
0.4	4.9	GO:0051121	lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.4	15.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.4	1.6	GO:0051660	establishment of centrosome localization(GO:0051660)
0.4	12.9	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.4	6.6	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.4	1.2	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.4	10.1	GO:0043588	skin development(GO:0043588)
0.4	1.5	GO:0046755	virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.4	14.7	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.4	9.6	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.4	1.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4	8.0	GO:0015701	bicarbonate transport(GO:0015701)
0.4	4.3	GO:0071222	cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.4	25.4	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.4	30.7	GO:0060326	cell chemotaxis(GO:0060326)
0.4	10.3	GO:0043171	peptide catabolic process(GO:0043171)
0.4	5.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.3	9.0	GO:0032506	cytokinetic process(GO:0032506)
0.3	2.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.3	3.7	GO:0039023	pronephric duct morphogenesis(GO:0039023)
0.3	1.3	GO:0001818	negative regulation of cytokine production(GO:0001818)
0.3	1.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	5.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.3	125.6	GO:0006955	immune response(GO:0006955)
0.3	4.8	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.3	14.6	GO:0070830	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3	1.2	GO:0033301	cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3	4.5	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.3	5.6	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.3	9.6	GO:0030098	lymphocyte differentiation(GO:0030098)
0.3	5.2	GO:0019935	cyclic-nucleotide-mediated signaling(GO:0019935)
0.3	0.9	GO:1903358	regulation of Golgi organization(GO:1903358)
0.3	0.8	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.3	4.0	GO:0032094	response to food(GO:0032094)
0.3	8.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3	9.4	GO:0048546	digestive tract morphogenesis(GO:0048546)
0.3	7.5	GO:0051923	sulfation(GO:0051923)
0.3	6.5	GO:0030322	stabilization of membrane potential(GO:0030322)
0.3	2.1	GO:0070933	histone H4 deacetylation(GO:0070933)
0.3	1.8	GO:0060217	hemangioblast cell differentiation(GO:0060217)
0.3	2.8	GO:0042572	retinol metabolic process(GO:0042572)
0.2	6.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.2	0.9	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2	12.5	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.2	13.8	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.2	3.7	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.2	4.1	GO:0007032	endosome organization(GO:0007032)
0.2	0.7	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219) negative regulation of phospholipid metabolic process(GO:1903726)
0.2	50.8	GO:0032970	regulation of actin filament-based process(GO:0032970)
0.2	9.6	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.2	15.7	GO:0048565	digestive tract development(GO:0048565)
0.2	4.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2	0.8	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2	3.2	GO:0002574	thrombocyte differentiation(GO:0002574)
0.2	10.7	GO:0034599	cellular response to oxidative stress(GO:0034599)
0.2	12.9	GO:0060348	bone development(GO:0060348)
0.2	1.7	GO:0006999	nuclear pore organization(GO:0006999)
0.2	2.8	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
0.2	10.5	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.2	5.7	GO:0030282	bone mineralization(GO:0030282)
0.2	1.0	GO:1902269	polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.2	0.7	GO:0019566	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1	8.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	1.0	GO:0035909	establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1	0.8	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	2.4	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	1.1	GO:0010737	protein kinase A signaling(GO:0010737)
0.1	5.0	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	2.2	GO:0009749	response to glucose(GO:0009749)
0.1	2.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	24.3	GO:0042127	regulation of cell proliferation(GO:0042127)
0.1	0.1	GO:0090342	regulation of cell aging(GO:0090342)
0.1	7.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	4.0	GO:0045332	phospholipid translocation(GO:0045332)
0.1	24.3	GO:0060047	heart contraction(GO:0060047)
0.1	0.9	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	3.0	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1	2.7	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.1	2.0	GO:0008272	sulfate transport(GO:0008272)
0.1	6.8	GO:0071560	transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1	0.9	GO:0071356	response to tumor necrosis factor(GO:0034612) cellular response to tumor necrosis factor(GO:0071356)
0.1	4.0	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	10.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.1	11.9	GO:0007626	locomotory behavior(GO:0007626)
0.1	0.4	GO:0061056	sclerotome development(GO:0061056)
0.1	4.3	GO:0010842	retina layer formation(GO:0010842)
0.1	39.6	GO:0006412	translation(GO:0006412)
0.1	1.9	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.1	11.8	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.1	0.3	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.1	0.9	GO:0042026	protein refolding(GO:0042026)
0.1	1.6	GO:1901215	negative regulation of neuron death(GO:1901215)
0.1	0.3	GO:0070291	N-acylethanolamine metabolic process(GO:0070291)
0.1	1.6	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	2.0	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1	0.3	GO:1904589	regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1	1.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1	2.3	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.1	2.4	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	0.3	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	2.9	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1	2.7	GO:1901800	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	6.2	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	1.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	7.6	GO:0042391	regulation of membrane potential(GO:0042391)
0.1	1.6	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	4.8	GO:0009410	response to xenobiotic stimulus(GO:0009410)
0.0	4.8	GO:0006821	chloride transport(GO:0006821)
0.0	2.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.4	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
0.0	1.1	GO:0003094	glomerular filtration(GO:0003094)
0.0	1.0	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	1.6	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	9.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	2.6	GO:0009306	protein secretion(GO:0009306)
0.0	1.9	GO:0016575	histone deacetylation(GO:0016575)
0.0	3.4	GO:0006364	rRNA processing(GO:0006364)
0.0	1.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	1.4	GO:0008360	regulation of cell shape(GO:0008360)
0.0	1.5	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.0	1.5	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.0	1.2	GO:1903706	regulation of hemopoiesis(GO:1903706)
0.0	2.0	GO:0006457	protein folding(GO:0006457)
0.0	1.5	GO:0000724	double-strand break repair via homologous recombination(GO:0000724)
0.0	1.1	GO:0003341	cilium movement(GO:0003341)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	23.1	GO:0043020	NADPH oxidase complex(GO:0043020)
2.5	12.5	GO:0097433	dense body(GO:0097433)
2.4	36.5	GO:0016328	lateral plasma membrane(GO:0016328)
2.2	11.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
2.2	15.4	GO:0030121	AP-1 adaptor complex(GO:0030121)
2.1	8.5	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
2.1	21.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.5	4.6	GO:0016528	sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
1.5	4.4	GO:0043614	multi-eIF complex(GO:0043614)
1.3	5.3	GO:0098842	postsynaptic early endosome(GO:0098842)
1.3	10.1	GO:0042613	MHC class II protein complex(GO:0042613)
1.2	16.9	GO:0002102	podosome(GO:0002102)
1.0	18.2	GO:0098844	postsynaptic endocytic zone membrane(GO:0098844)
1.0	17.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.9	7.8	GO:0031526	brush border membrane(GO:0031526)
0.8	3.8	GO:1990923	PET complex(GO:1990923)
0.7	5.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.7	44.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.7	30.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.7	5.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.6	2.5	GO:0033186	CAF-1 complex(GO:0033186)
0.6	5.0	GO:0070552	BRISC complex(GO:0070552)
0.6	8.4	GO:0000815	ESCRT III complex(GO:0000815)
0.6	6.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.5	11.6	GO:0030131	clathrin adaptor complex(GO:0030131)
0.5	4.7	GO:0071797	LUBAC complex(GO:0071797)
0.5	38.8	GO:0015935	small ribosomal subunit(GO:0015935)
0.5	2.6	GO:0043198	dendritic shaft(GO:0043198)
0.5	49.5	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.5	3.1	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5	5.0	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.5	131.9	GO:0005764	lysosome(GO:0005764)
0.5	6.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.5	5.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.4	40.9	GO:0031201	SNARE complex(GO:0031201)
0.4	2.5	GO:0070876	SOSS complex(GO:0070876)
0.4	107.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.4	56.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.4	1.5	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3	2.4	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	7.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.3	10.9	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.3	2.9	GO:0000974	Prp19 complex(GO:0000974)
0.3	24.8	GO:0005789	endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.3	5.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.3	3.0	GO:0005903	brush border(GO:0005903)
0.3	11.4	GO:0031012	extracellular matrix(GO:0031012)
0.3	6.6	GO:0005685	U1 snRNP(GO:0005685)
0.3	0.9	GO:0090443	FAR/SIN/STRIPAK complex(GO:0090443)
0.3	2.0	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3	5.3	GO:0009925	basal plasma membrane(GO:0009925)
0.2	2.7	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	1.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.2	0.9	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	1.2	GO:0070390	transcription export complex 2(GO:0070390)
0.2	12.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2	0.6	GO:0097361	CIA complex(GO:0097361)
0.2	16.1	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.2	5.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.2	7.4	GO:0016514	SWI/SNF complex(GO:0016514)
0.2	9.3	GO:0005811	lipid particle(GO:0005811)
0.2	2.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	1.7	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.2	10.0	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.2	0.7	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2	18.5	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.2	6.5	GO:0031105	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2	2.1	GO:0017119	Golgi transport complex(GO:0017119)
0.2	197.9	GO:0005615	extracellular space(GO:0005615)
0.1	1.6	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	6.9	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	17.1	GO:0043296	apical junction complex(GO:0043296)
0.1	10.2	GO:0005802	trans-Golgi network(GO:0005802)
0.1	0.8	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	46.4	GO:0015629	actin cytoskeleton(GO:0015629)
0.1	75.3	GO:0005576	extracellular region(GO:0005576)
0.1	1.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	5.1	GO:0034707	chloride channel complex(GO:0034707)
0.1	1.5	GO:0031902	late endosome membrane(GO:0031902)
0.1	4.0	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	6.2	GO:0010008	endosome membrane(GO:0010008)
0.1	5.6	GO:0031965	nuclear membrane(GO:0031965)
0.1	3.5	GO:0055037	recycling endosome(GO:0055037)
0.1	0.6	GO:0070652	HAUS complex(GO:0070652)
0.1	0.8	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	0.3	GO:0035301	Hedgehog signaling complex(GO:0035301)
0.1	19.6	GO:0005730	nucleolus(GO:0005730)
0.1	0.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	17.8	GO:0000785	chromatin(GO:0000785)
0.1	11.2	GO:0005938	cell cortex(GO:0005938)
0.1	4.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	0.5	GO:0005682	U5 snRNP(GO:0005682)
0.1	0.9	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	2.2	GO:0030139	endocytic vesicle(GO:0030139)
0.0	0.8	GO:0060170	ciliary membrane(GO:0060170)
0.0	1.9	GO:0000139	Golgi membrane(GO:0000139)
0.0	2.9	GO:0005871	kinesin complex(GO:0005871)
0.0	3.3	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	2.0	GO:0000502	proteasome complex(GO:0000502)
0.0	6.4	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	25.7	GO:0005829	cytosol(GO:0005829)
0.0	1.7	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	113.4	GO:0016021	integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	25.6	GO:0004560	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
6.1	36.5	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
6.0	23.9	GO:0047134	protein-disulfide reductase activity(GO:0047134)
4.8	19.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
4.4	13.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
4.0	20.1	GO:0008743	L-threonine 3-dehydrogenase activity(GO:0008743)
3.8	41.3	GO:0004568	chitinase activity(GO:0004568)
3.4	13.7	GO:0017064	fatty acid amide hydrolase activity(GO:0017064)
2.9	8.6	GO:0043185	vascular endothelial growth factor receptor 3 binding(GO:0043185)
2.7	13.7	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.7	8.1	GO:0042806	fucose binding(GO:0042806)
2.6	7.8	GO:0031752	D5 dopamine receptor binding(GO:0031752)
2.6	10.2	GO:0004475	mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
2.5	12.5	GO:0098973	structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
2.1	10.6	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.1	10.5	GO:0042609	CD4 receptor binding(GO:0042609)
2.0	20.1	GO:0050700	CARD domain binding(GO:0050700)
2.0	44.1	GO:0042289	MHC class II protein binding(GO:0042289)
1.9	5.8	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086)
1.8	11.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.8	8.8	GO:0008432	JUN kinase binding(GO:0008432)
1.7	11.9	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
1.7	6.6	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
1.6	4.9	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
1.6	6.5	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
1.6	12.4	GO:0003993	acid phosphatase activity(GO:0003993)
1.5	13.7	GO:0016176	superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.3	26.4	GO:0004000	adenosine deaminase activity(GO:0004000)
1.3	13.1	GO:0004530	deoxyribonuclease I activity(GO:0004530)
1.3	18.8	GO:0051117	ATPase binding(GO:0051117)
1.3	13.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
1.2	11.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.2	4.9	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.2	14.5	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
1.2	11.8	GO:0016936	galactoside binding(GO:0016936)
1.2	6.9	GO:0015616	DNA translocase activity(GO:0015616)
1.2	51.9	GO:0048020	CCR chemokine receptor binding(GO:0048020)
1.1	21.9	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
1.1	13.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
1.1	5.3	GO:0038132	neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
1.0	11.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.9	7.6	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.9	3.6	GO:0044548	S100 protein binding(GO:0044548)
0.9	2.7	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.9	7.1	GO:0030619	U1 snRNA binding(GO:0030619)
0.9	9.4	GO:0005537	mannose binding(GO:0005537)
0.8	2.5	GO:0047804	cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.8	2.5	GO:0032184	SUMO polymer binding(GO:0032184)
0.8	5.7	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.8	4.0	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.8	7.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.8	4.8	GO:0032217	riboflavin transporter activity(GO:0032217)
0.8	3.9	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.8	10.9	GO:0008266	poly(U) RNA binding(GO:0008266)
0.8	33.0	GO:0019843	rRNA binding(GO:0019843)
0.8	9.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.7	11.7	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.7	2.2	GO:0004557	alpha-galactosidase activity(GO:0004557)
0.7	2.9	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.7	4.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7	12.7	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.7	4.6	GO:0004630	phospholipase D activity(GO:0004630)
0.6	7.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	6.9	GO:0004309	exopolyphosphatase activity(GO:0004309)
0.6	9.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.6	44.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.6	5.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.6	3.7	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.6	3.1	GO:0046592	polyamine oxidase activity(GO:0046592)
0.6	15.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.6	8.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.6	1.8	GO:0080132	fatty acid alpha-hydroxylase activity(GO:0080132)
0.6	3.0	GO:0001735	prenylcysteine oxidase activity(GO:0001735)
0.6	23.4	GO:0019957	C-C chemokine binding(GO:0019957)
0.6	5.6	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.5	12.5	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5	17.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.5	1.6	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.5	2.7	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.5	1.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.5	3.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.5	6.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.5	39.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5	3.8	GO:0034584	piRNA binding(GO:0034584)
0.5	4.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5	11.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.5	9.7	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.5	4.6	GO:0008172	S-methyltransferase activity(GO:0008172)
0.5	5.0	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4	24.4	GO:0004521	endoribonuclease activity(GO:0004521)
0.4	66.3	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.4	5.2	GO:0005163	nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.4	5.1	GO:0008026	ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.4	2.2	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.4	2.9	GO:0015154	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4	10.0	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.4	28.8	GO:0004896	cytokine receptor activity(GO:0004896)
0.4	7.4	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3	21.3	GO:0031072	heat shock protein binding(GO:0031072)
0.3	2.8	GO:0001222	transcription corepressor binding(GO:0001222)
0.3	9.3	GO:0004697	protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.3	32.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.3	7.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.3	4.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3	8.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3	14.6	GO:0031593	polyubiquitin binding(GO:0031593)
0.3	0.8	GO:0005502	11-cis retinal binding(GO:0005502)
0.3	18.2	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.3	3.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.3	2.8	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.3	1.9	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.3	1.3	GO:1902388	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.3	16.2	GO:0030276	clathrin binding(GO:0030276)
0.3	11.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.3	6.5	GO:0022840	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.2	40.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	90.5	GO:0051015	actin filament binding(GO:0051015)
0.2	36.1	GO:0005125	cytokine activity(GO:0005125)
0.2	6.7	GO:0016208	AMP binding(GO:0016208)
0.2	6.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	2.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.2	25.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	5.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	1.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	48.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	18.1	GO:0005254	chloride channel activity(GO:0005254)
0.2	2.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2	78.7	GO:0003924	GTPase activity(GO:0003924)
0.2	4.6	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.2	9.2	GO:0050661	NADP binding(GO:0050661)
0.2	1.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.2	38.1	GO:0005525	GTP binding(GO:0005525)
0.2	5.5	GO:0016209	antioxidant activity(GO:0016209)
0.2	1.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2	8.8	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	7.8	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2	1.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.2	0.7	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.2	4.0	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.2	6.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.2	2.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.2	2.4	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.2	4.8	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.2	1.2	GO:0001130	bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1	2.6	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	11.1	GO:0003724	RNA helicase activity(GO:0003724)
0.1	2.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	7.1	GO:0005126	cytokine receptor binding(GO:0005126)
0.1	11.5	GO:0045296	cadherin binding(GO:0045296)
0.1	20.1	GO:0020037	heme binding(GO:0020037)
0.1	0.4	GO:0019777	Atg12 transferase activity(GO:0019777)
0.1	4.3	GO:0003684	damaged DNA binding(GO:0003684)
0.1	9.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.1	16.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	41.7	GO:0030695	GTPase regulator activity(GO:0030695)
0.1	1.2	GO:0005158	insulin receptor binding(GO:0005158)
0.1	8.7	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	30.7	GO:0003779	actin binding(GO:0003779)
0.1	9.1	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.1	6.0	GO:0051082	unfolded protein binding(GO:0051082)
0.1	0.4	GO:0001221	transcription cofactor binding(GO:0001221)
0.1	2.2	GO:0015248	sterol transporter activity(GO:0015248)
0.1	1.9	GO:0004659	prenyltransferase activity(GO:0004659)
0.1	1.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	4.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	2.7	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	1.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.9	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	3.4	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.1	6.5	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	1.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	1.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	54.6	GO:0004888	transmembrane signaling receptor activity(GO:0004888)
0.0	9.7	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	0.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	1.6	GO:0004175	endopeptidase activity(GO:0004175)
0.0	0.6	GO:0031386	protein tag(GO:0031386)
0.0	0.3	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	5.0	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0	2.9	GO:0008083	growth factor activity(GO:0008083)
0.0	1.4	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	3.6	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	5.8	GO:0008134	transcription factor binding(GO:0008134)
0.0	2.9	GO:0003777	microtubule motor activity(GO:0003777)
0.0	3.6	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
1.1	28.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.9	15.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.9	12.9	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.9	7.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.8	25.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.8	22.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.8	37.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.8	23.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.8	14.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.7	13.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.7	43.3	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.6	4.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.6	8.1	PID ALK2 PATHWAY	ALK2 signaling events
0.5	17.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.5	4.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	8.0	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.4	14.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.4	7.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.3	9.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	2.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	3.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	23.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	7.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.2	4.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	6.9	PID PLK1 PATHWAY	PLK1 signaling events
0.2	5.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.2	25.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	1.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	1.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	2.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	10.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	2.6	PID BCR 5PATHWAY	BCR signaling pathway
0.1	3.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	5.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	3.8	PID E2F PATHWAY	E2F transcription factor network
0.1	2.5	PID P73PATHWAY	p73 transcription factor network
0.1	3.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	0.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	7.3	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	4.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	49.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
2.8	25.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.8	19.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.3	19.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
1.2	8.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
1.2	13.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.1	11.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
1.0	18.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.0	12.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
1.0	13.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.9	11.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.9	11.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.9	16.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.9	16.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.8	3.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.8	15.2	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.7	2.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	4.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.7	10.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.7	79.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.6	7.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6	15.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.6	14.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.6	5.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.5	13.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5	11.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.5	10.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.5	9.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.4	8.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	3.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	5.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	2.6	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.3	5.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.3	12.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3	2.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	4.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	1.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	7.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	8.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	4.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	1.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	6.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	12.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	6.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	2.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	1.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	8.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	7.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	10.6	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	2.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	3.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	2.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	7.3	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.1	2.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.8	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	0.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.7	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1	1.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	3.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	5.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.8	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions