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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Z-value: 2.09

Motif logo

Transcription factors associated with sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

Gene Symbol Gene ID Gene Info
ENSDARG00000011870 sp8 transcription factor a
ENSDARG00000056666 sp8 transcription factor b
ENSDARG00000005186 sp4 transcription factor
ENSDARG00000001549 sp3a transcription factor
ENSDARG00000005846 Sp5 transcription factor b
ENSDARG00000079922 Kruppel-like factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp8bdr11_v1_chr16_+_19536614_19536761-0.723.0e-16Click!
FO704755.1dr11_v1_chr6_+_3809346_3809346-0.406.0e-05Click!
sp8adr11_v1_chr19_-_2317558_2317558-0.372.6e-04Click!
sp3adr11_v1_chr9_+_2762270_27624150.339.9e-04Click!
klf4dr11_v1_chr21_-_435466_4354660.188.1e-02Click!
sp4dr11_v1_chr19_+_2546775_25467750.179.4e-02Click!

Activity profile of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Sorted Z-values of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_17197546 64.69 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr12_+_46634736 39.91 ENSDART00000008009
tripartite motif containing 16
chr10_-_41352502 35.37 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr20_-_54564018 32.84 ENSDART00000099832
zgc:153012
chr3_+_1211242 31.75 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr24_-_11076400 30.86 ENSDART00000003195
charged multivesicular body protein 4C
chr21_-_32436679 29.10 ENSDART00000076974
glutamine-fructose-6-phosphate transaminase 2
chr10_-_1625080 29.06 ENSDART00000137285
nucleoporin 155
chr16_-_17713859 28.51 ENSDART00000149275
zgc:174935
chr22_+_11756040 27.41 ENSDART00000105808
keratin 97
chr21_-_11646878 27.13 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr25_-_22187397 26.61 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr21_-_43328056 26.56 ENSDART00000114955
sosondowah ankyrin repeat domain family member Aa
chr5_-_1047504 26.44 ENSDART00000159346
methyl-CpG binding domain protein 2
chr22_+_661505 25.84 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_+_19299309 25.49 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr2_+_68789 25.17 ENSDART00000058569
claudin 1
chr15_+_17752928 24.50 ENSDART00000155314
si:ch211-213d14.2
chr24_+_42132962 23.91 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr6_-_60104628 23.61 ENSDART00000057463
ENSDART00000169188
prostate transmembrane protein, androgen induced 1
chr24_+_37449893 23.57 ENSDART00000164405
NLR family, CARD domain containing 3
chr24_+_35387517 23.47 ENSDART00000058571
snail family zinc finger 2
chr22_+_1006573 23.27 ENSDART00000123458
peroxisome proliferator-activated receptor delta a
chr1_-_59232267 23.26 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr19_+_48111285 23.08 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr21_+_25236297 22.67 ENSDART00000112783
transmembrane protein 45B
chr6_-_7776612 22.25 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr2_+_30379650 22.21 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr16_+_28754403 22.18 ENSDART00000103340
S100 calcium binding protein V1
chr10_-_2942900 21.54 ENSDART00000002622
occludin a
chr15_+_28410664 21.51 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr22_+_835728 21.37 ENSDART00000003325
DENN/MADD domain containing 2Db
chr8_+_23213320 21.10 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr21_-_39024754 20.72 ENSDART00000056878
tnf receptor-associated factor 4b
chr2_+_35880600 20.56 ENSDART00000004277
laminin, gamma 1
chr15_+_46344655 20.48 ENSDART00000155893
si:ch1073-340i21.2
chr6_+_102506 20.47 ENSDART00000172678
low density lipoprotein receptor b
chr24_+_42127983 20.09 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
WW domain containing E3 ubiquitin protein ligase 1
chr18_+_6558338 19.92 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr25_+_4635355 19.83 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr22_+_661711 19.65 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_27456804 18.43 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr25_+_37443194 18.40 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr22_+_883678 18.24 ENSDART00000140588
serine/threonine kinase 38b
chr2_-_51109476 18.21 ENSDART00000168286
si:ch73-52e5.1
chr19_+_9305964 17.88 ENSDART00000136241
si:ch73-15n24.1
chr16_+_53455638 17.65 ENSDART00000045792
ENSDART00000154189
RNA binding motif protein 24b
chr22_+_24645325 17.46 ENSDART00000159531
lysophosphatidic acid receptor 3
chr14_+_7048930 17.45 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr12_-_4331117 17.28 ENSDART00000008893
carbonic anhydrase XVa
chr6_+_41503854 17.28 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr24_-_36593876 17.22 ENSDART00000160901

chr3_-_40276057 17.18 ENSDART00000132225
ENSDART00000074737
serine hydroxymethyltransferase 1 (soluble)
chr2_+_413370 17.16 ENSDART00000122138
myosin light chain kinase family, member 4a
chr11_+_13524504 16.97 ENSDART00000139889
arrestin domain containing 2
chr12_-_4540564 16.94 ENSDART00000106566

chr18_-_6803424 16.90 ENSDART00000142647
si:dkey-266m15.5
chr7_+_1473929 16.86 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr23_-_10254288 16.82 ENSDART00000081215
keratin 8
chr21_-_308852 16.67 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr22_+_11775269 16.64 ENSDART00000140272
keratin 96
chr10_-_4980150 16.43 ENSDART00000093228
methionine adenosyltransferase II, alpha-like
chr16_-_12316979 15.87 ENSDART00000182392
transient receptor potential cation channel, subfamily V, member 6
chr9_-_34269066 15.60 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr12_+_23424108 15.54 ENSDART00000077732
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr1_-_53907092 15.46 ENSDART00000007732
calpain 9
chr22_-_607812 15.44 ENSDART00000145983
cyclin-dependent kinase inhibitor 1A
chr24_-_29777413 15.42 ENSDART00000087724
wu:fj05g07
chr20_-_7293837 15.26 ENSDART00000100060
desmocollin 2 like
chr5_-_23696926 15.25 ENSDART00000021462
ring finger protein 128a
chr19_+_43119698 15.20 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr3_-_32541033 15.16 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr4_+_57093908 15.14 ENSDART00000170198
si:ch211-238e22.5
chr3_+_36972586 15.05 ENSDART00000102784
si:ch211-18i17.2
chr20_-_9580446 14.92 ENSDART00000014168
zinc finger protein 36, C3H type-like 1b
chr24_+_17005647 14.87 ENSDART00000149149
zinc finger protein, X-linked
chr3_+_32492467 14.81 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr9_+_1654284 14.79 ENSDART00000062854
nuclear factor, erythroid 2-like 2a
chr15_+_46357080 14.68 ENSDART00000155571
ENSDART00000156541
wu:fb18f06
chr4_-_4612116 14.59 ENSDART00000130601
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr25_+_3104959 14.45 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr5_-_1047222 14.41 ENSDART00000181112
methyl-CpG binding domain protein 2
chr8_+_47099033 14.30 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr22_+_396840 14.16 ENSDART00000163198
capping protein (actin filament) muscle Z-line, beta
chr21_-_32060993 14.14 ENSDART00000131651
si:ch211-160j14.2
chr3_+_29469283 14.14 ENSDART00000103592
family with sequence similarity 83, member Fa
chr12_+_48841182 14.07 ENSDART00000109315
ENSDART00000185609
ENSDART00000187217
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr1_-_54107321 13.81 ENSDART00000148382
ENSDART00000150357
regulatory factor X, 1b (influences HLA class II expression)
chr1_+_59538755 13.71 ENSDART00000166354
Sp6 transcription factor
chr3_+_726000 13.56 ENSDART00000158510
diverse immunoglobulin domain-containing protein 1.17
chr24_-_32582378 13.49 ENSDART00000066590
retinol dehydrogenase 12, like
chr25_+_34013093 13.48 ENSDART00000011967
annexin A2a
chr4_+_78008298 13.41 ENSDART00000174237
chaperonin containing TCP1, subunit 2 (beta)
chr21_+_1647990 13.39 ENSDART00000148540
ferrochelatase
chr14_+_97017 13.38 ENSDART00000159300
ENSDART00000169523
minichromosome maintenance complex component 7
chr8_+_6576940 13.32 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr19_-_6193448 13.30 ENSDART00000151405
Ets2 repressor factor
chr22_+_20720808 13.25 ENSDART00000171321
si:dkey-211f22.5
chr19_+_19989380 13.00 ENSDART00000142841
oxysterol binding protein-like 3a
chr25_+_186583 12.83 ENSDART00000161504
PCNA clamp associated factor
chr25_+_6122823 12.70 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr24_+_38671054 12.69 ENSDART00000154214
si:ch73-70c5.1
chr15_+_46356879 12.50 ENSDART00000154388
wu:fb18f06
chr25_+_3306858 12.44 ENSDART00000137077
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr20_+_26538137 12.33 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr11_-_25384213 12.28 ENSDART00000103650
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
chr12_+_48841419 12.25 ENSDART00000125331
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr15_-_20468302 12.11 ENSDART00000018514
deltaC
chr1_-_59216197 12.07 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr8_-_53490376 12.04 ENSDART00000158789
choline dehydrogenase
chr18_+_6558146 12.03 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr7_-_52498175 12.00 ENSDART00000129769
cingulin-like 1
chr8_+_53051701 11.91 ENSDART00000131514
NAD kinase a
chr18_+_44649804 11.89 ENSDART00000059063
EH-domain containing 2b
chr2_+_55365727 11.89 ENSDART00000162943

chr7_+_38349667 11.88 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr20_+_34400715 11.86 ENSDART00000061632
family with sequence similarity 129, member Aa
chr8_+_8927870 11.80 ENSDART00000081985
Pim-2 proto-oncogene, serine/threonine kinase
chr1_-_51734524 11.77 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr17_+_51746830 11.70 ENSDART00000184230
ornithine decarboxylase 1
chr21_+_43328685 11.68 ENSDART00000109620
ENSDART00000139668
septin 8a
chr23_-_10177442 11.65 ENSDART00000144280
ENSDART00000129044
keratin 5
chr23_-_5818992 11.62 ENSDART00000148730
cysteine and glycine-rich protein 1a
chr22_-_16275236 11.51 ENSDART00000149051
cell division cycle 14Ab
chr6_-_39313027 11.40 ENSDART00000012644
keratin 4
chr3_+_5575313 11.27 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr17_+_389218 11.22 ENSDART00000162898
si:rp71-62i8.1
chr8_+_52637507 11.11 ENSDART00000163830
si:dkey-90l8.3
chr21_-_13856689 11.09 ENSDART00000102197
family with sequence similarity 129, member Ba
chr8_+_19356072 10.99 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr8_+_51958968 10.97 ENSDART00000139509
ENSDART00000186544
guanine nucleotide binding protein (G protein), alpha 14a
chr19_-_11031145 10.96 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tropomyosin 3
chr4_-_17409533 10.94 ENSDART00000011943
phenylalanine hydroxylase
chr13_-_42673978 10.87 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr16_+_23431189 10.81 ENSDART00000004679
ictacalcin
chr6_+_3334710 10.81 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr14_+_4151379 10.81 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr5_+_46293850 10.62 ENSDART00000140636
si:ch211-130m23.2
chr5_+_66132394 10.55 ENSDART00000073892
zgc:114041
chr10_-_15048781 10.54 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
chr23_-_31436524 10.53 ENSDART00000140519
zgc:153284
chr6_+_49926115 10.50 ENSDART00000018523
adenosylhomocysteinase
chr23_-_2513300 10.49 ENSDART00000067652
snail family zinc finger 1b
chr23_-_31645760 10.40 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr6_-_607063 10.37 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr18_-_48547564 10.34 ENSDART00000138607
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr3_+_32410746 10.19 ENSDART00000025496
RAS related
chr21_-_5056812 10.15 ENSDART00000139713
ENSDART00000140859
zgc:77838
chr14_+_26439227 10.12 ENSDART00000054183
G protein-coupled receptor 137
chr10_+_31809226 10.12 ENSDART00000087898
forkhead box O1 b
chr10_-_44017642 9.97 ENSDART00000135240
ENSDART00000014669
acyl-CoA dehydrogenase short chain
chr5_+_72152813 9.94 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr16_+_23282655 9.91 ENSDART00000015956
ephrin-A1b
chr4_-_20181964 9.88 ENSDART00000022539
fibrinogen-like 2a
chr8_+_29962635 9.87 ENSDART00000007640
patched 1
chr19_-_1855368 9.84 ENSDART00000029646
ribosomal protein, large, P1
chr2_+_48073972 9.81 ENSDART00000186442
Kruppel-like factor 6b
chr25_+_3306620 9.77 ENSDART00000182085
ENSDART00000034704
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr10_-_15053507 9.64 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr13_-_36582341 9.58 ENSDART00000137335
lectin, galactoside binding soluble 3a
chr8_-_2616326 9.51 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr12_+_695619 9.46 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr25_-_37284370 9.44 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr19_+_19988869 9.37 ENSDART00000151024
oxysterol binding protein-like 3a
chr2_-_48826707 9.32 ENSDART00000134711
supervillin b
chr23_-_45398622 9.32 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr25_+_10547228 9.31 ENSDART00000067678
zgc:110339
chr2_+_48074243 9.27 ENSDART00000056291
Kruppel-like factor 6b
chr25_+_34915762 9.25 ENSDART00000191776
syntrophin, beta 2
chr11_+_11719575 9.20 ENSDART00000003891
junction plakoglobin a
chr5_-_68022631 9.18 ENSDART00000143199
WAS protein family, member 3a
chr17_-_20558961 9.15 ENSDART00000155993
SH3 and PX domains 2Ab
chr7_+_58730201 9.09 ENSDART00000073640
pleiomorphic adenoma gene 1
chr6_+_50451337 9.08 ENSDART00000155051
myelocytomatosis oncogene homolog
chr24_-_4450238 9.02 ENSDART00000066835
frizzled class receptor 8a
chr17_+_24615091 9.01 ENSDART00000064739
ribosomal protein L13a
chr15_+_36105581 9.00 ENSDART00000184099
collagen, type IV, alpha 3
chr21_-_11632403 9.00 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr8_-_4100365 8.95 ENSDART00000142846
cut-like homeobox 2b
chr8_+_7033049 8.93 ENSDART00000064172
ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr9_+_30421489 8.88 ENSDART00000145025
ENSDART00000132058
zgc:113314
chr19_-_6193067 8.87 ENSDART00000092656
ENSDART00000140347
Ets2 repressor factor
chr2_-_51630555 8.85 ENSDART00000171746
polymeric immunoglobulin receptor
chr23_-_45407631 8.83 ENSDART00000148484
ENSDART00000150186
zgc:101853
chr22_-_27136451 8.83 ENSDART00000153589
si:dkey-16m19.1
chr7_-_10560964 8.73 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_-_46505691 8.62 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hyaluronan and proteoglycan link protein 1a
chr13_+_25410594 8.61 ENSDART00000112092
calcium homeostasis modulator 3
chr19_+_46113828 8.61 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr21_+_15713097 8.61 ENSDART00000015841
glutathione S-transferase theta 1b
chr6_-_40657653 8.56 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr8_-_38201415 8.54 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr5_+_4533244 8.54 ENSDART00000158826
Danio rerio thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 (LOC561325), mRNA.
chr1_+_22654875 8.53 ENSDART00000019698
ENSDART00000161874
annexin A5b
chr11_+_329687 8.51 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr25_-_35960229 8.50 ENSDART00000073434
sorting nexin 20
chr25_-_16724913 8.50 ENSDART00000157075
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 2
chr13_+_22480496 8.48 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr1_-_54100988 8.39 ENSDART00000192662
regulatory factor X, 1b (influences HLA class II expression)
chr10_-_320153 8.38 ENSDART00000161493
v-akt murine thymoma viral oncogene homolog 2, like

Network of associatons between targets according to the STRING database.

First level regulatory network of sp8a+sp8b_sp4_rsl1d1+sp3a_klf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 29.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
6.7 6.7 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
6.6 26.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
6.2 43.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
6.1 18.3 GO:0002369 T cell cytokine production(GO:0002369)
5.8 17.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
5.7 17.2 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
4.8 23.9 GO:0002159 desmosome assembly(GO:0002159)
4.6 18.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
4.4 22.2 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
4.2 25.5 GO:0032367 intracellular cholesterol transport(GO:0032367)
4.0 12.0 GO:0019695 choline metabolic process(GO:0019695)
4.0 15.9 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
3.6 10.8 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
3.5 24.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
3.4 23.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
3.1 15.3 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
3.0 12.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
3.0 9.0 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
3.0 8.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
2.8 8.4 GO:0007571 age-dependent general metabolic decline(GO:0007571)
2.8 19.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
2.7 8.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
2.7 13.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
2.7 16.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
2.7 24.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
2.6 7.8 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
2.6 7.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
2.5 12.7 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
2.5 32.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
2.5 10.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.3 16.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.3 6.8 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
2.2 2.2 GO:0006572 tyrosine catabolic process(GO:0006572)
2.2 8.9 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
2.1 8.6 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
2.1 10.5 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
2.1 8.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
2.1 16.7 GO:0046546 development of primary male sexual characteristics(GO:0046546)
2.1 10.3 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
2.0 6.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
2.0 6.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
2.0 4.0 GO:1903428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
1.9 7.8 GO:0002934 desmosome organization(GO:0002934)
1.9 5.8 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.9 17.4 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
1.9 5.6 GO:0005997 xylulose metabolic process(GO:0005997)
1.8 7.2 GO:0006526 arginine biosynthetic process(GO:0006526)
1.8 7.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
1.8 21.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.7 12.2 GO:0006741 NADP biosynthetic process(GO:0006741)
1.7 12.2 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.7 12.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
1.7 1.7 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.7 5.0 GO:0097384 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.7 6.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
1.7 3.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.6 4.8 GO:0071896 protein localization to adherens junction(GO:0071896)
1.6 6.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.6 4.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.5 10.7 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
1.5 14.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
1.5 7.4 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
1.5 10.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
1.4 15.9 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.4 23.1 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.4 51.5 GO:0050821 protein stabilization(GO:0050821)
1.4 11.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.3 18.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.3 5.2 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
1.3 30.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.3 5.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.3 2.6 GO:1902745 positive regulation of lamellipodium organization(GO:1902745)
1.2 3.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.2 1.2 GO:0010878 cholesterol storage(GO:0010878) regulation of cholesterol storage(GO:0010885)
1.2 58.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
1.2 3.6 GO:0048785 hatching gland development(GO:0048785)
1.2 4.7 GO:0001782 B cell homeostasis(GO:0001782)
1.2 4.7 GO:0008356 asymmetric cell division(GO:0008356)
1.2 3.5 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
1.2 6.9 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
1.1 11.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.1 11.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
1.1 4.5 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
1.1 7.8 GO:0040016 embryonic cleavage(GO:0040016)
1.1 8.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.1 23.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.0 21.0 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
1.0 4.2 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.0 3.1 GO:0003071 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
1.0 15.4 GO:0035904 aorta development(GO:0035904)
1.0 2.0 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.0 4.1 GO:0052746 inositol phosphorylation(GO:0052746)
1.0 15.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
1.0 3.0 GO:0000103 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.0 6.0 GO:0070650 actin filament bundle distribution(GO:0070650)
1.0 2.0 GO:0001778 plasma membrane repair(GO:0001778)
1.0 5.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.0 3.9 GO:1903723 negative regulation of centriole elongation(GO:1903723)
1.0 5.8 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
1.0 8.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.9 8.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.9 10.9 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.9 13.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.9 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.9 3.5 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.9 5.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.9 5.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.9 10.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.9 2.6 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.9 4.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.9 2.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.9 7.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.9 11.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.9 2.6 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.8 29.7 GO:0007586 digestion(GO:0007586)
0.8 2.5 GO:0035973 aggrephagy(GO:0035973)
0.8 17.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.8 0.8 GO:0061195 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.8 10.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.8 3.3 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.8 3.3 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.8 3.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.8 3.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.8 6.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.8 4.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 12.8 GO:0019985 translesion synthesis(GO:0019985)
0.8 2.4 GO:0098773 skin epidermis development(GO:0098773)
0.8 5.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.8 3.1 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.7 11.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.7 15.5 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.7 3.0 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.7 2.2 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.7 8.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.7 2.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.7 2.9 GO:0030224 monocyte differentiation(GO:0030224)
0.7 3.6 GO:0048730 epidermis morphogenesis(GO:0048730)
0.7 10.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.7 4.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 2.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.7 3.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.7 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.7 16.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.7 8.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.7 13.4 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.7 2.7 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.6 5.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 2.6 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.6 3.2 GO:0019478 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.6 7.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.6 1.9 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.6 3.8 GO:0071800 podosome assembly(GO:0071800)
0.6 4.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.6 4.5 GO:0006552 leucine catabolic process(GO:0006552)
0.6 5.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.6 9.4 GO:0046130 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.6 2.5 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.6 9.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.6 3.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.6 6.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.6 8.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.6 4.1 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.6 1.8 GO:0034214 protein hexamerization(GO:0034214)
0.6 4.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.6 8.6 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.6 6.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 5.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.6 2.8 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.6 2.2 GO:1990402 embryonic liver development(GO:1990402)
0.6 1.7 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.6 5.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.6 5.6 GO:0031639 plasminogen activation(GO:0031639)
0.6 3.9 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.5 16.7 GO:0051014 actin filament severing(GO:0051014)
0.5 4.3 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.5 3.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.5 0.5 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.5 1.6 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.5 2.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 5.7 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.5 3.0 GO:0035989 tendon development(GO:0035989)
0.5 46.8 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.5 3.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.5 2.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.5 3.9 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.5 3.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.5 12.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.5 1.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.5 5.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.5 10.1 GO:0015671 oxygen transport(GO:0015671)
0.5 2.9 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.5 33.4 GO:0007043 cell-cell junction assembly(GO:0007043)
0.5 2.3 GO:2000765 regulation of cytoplasmic translation(GO:2000765)
0.5 3.3 GO:0030104 water homeostasis(GO:0030104)
0.5 5.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.5 2.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.5 1.8 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.5 1.8 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.4 8.1 GO:0043687 post-translational protein modification(GO:0043687)
0.4 4.0 GO:0090398 cellular senescence(GO:0090398)
0.4 8.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.4 6.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.3 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.4 20.0 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.4 15.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 1.3 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.4 2.5 GO:0061055 myotome development(GO:0061055)
0.4 6.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 5.5 GO:0070189 kynurenine metabolic process(GO:0070189)
0.4 2.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.4 5.9 GO:0009409 response to cold(GO:0009409)
0.4 2.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.4 2.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 3.7 GO:0003160 endocardium morphogenesis(GO:0003160)
0.4 4.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.4 2.8 GO:0060017 parathyroid gland development(GO:0060017)
0.4 23.3 GO:0006414 translational elongation(GO:0006414)
0.4 2.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.4 12.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 2.0 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.4 7.8 GO:0097178 ruffle assembly(GO:0097178)
0.4 5.4 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.4 12.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 10.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.4 6.1 GO:0042574 retinal metabolic process(GO:0042574)
0.4 1.9 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.4 1.1 GO:0042539 hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.4 0.4 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.4 6.0 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.4 3.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.4 4.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 2.2 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.4 19.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.4 1.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 9.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.4 3.9 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 4.6 GO:0043248 proteasome assembly(GO:0043248)
0.4 23.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.4 9.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.3 3.5 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.3 1.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.3 3.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.3 4.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 4.1 GO:0002757 immune response-activating signal transduction(GO:0002757)
0.3 3.1 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.3 12.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.3 2.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.3 3.0 GO:0043144 snoRNA processing(GO:0043144)
0.3 3.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 1.6 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.3 2.6 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.3 4.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 19.1 GO:0042493 response to drug(GO:0042493)
0.3 2.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.3 1.6 GO:0050680 negative regulation of endothelial cell proliferation(GO:0001937) negative regulation of epithelial cell proliferation(GO:0050680)
0.3 7.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 1.9 GO:0010269 response to selenium ion(GO:0010269)
0.3 3.4 GO:0009303 rRNA transcription(GO:0009303)
0.3 3.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 0.9 GO:0060343 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.3 1.2 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.3 1.8 GO:0014823 response to activity(GO:0014823)
0.3 5.3 GO:0051764 actin crosslink formation(GO:0051764)
0.3 4.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.3 1.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 0.6 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.3 8.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.3 3.2 GO:0006611 protein export from nucleus(GO:0006611)
0.3 6.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 1.7 GO:0060149 positive regulation of translational initiation(GO:0045948) negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 19.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.3 1.1 GO:0090342 regulation of cell aging(GO:0090342)
0.3 18.7 GO:0001945 lymph vessel development(GO:0001945)
0.3 0.8 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.3 2.2 GO:0051013 microtubule severing(GO:0051013)
0.3 16.1 GO:0015914 phospholipid transport(GO:0015914)
0.3 2.3 GO:0042026 protein refolding(GO:0042026)
0.3 1.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 9.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.3 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.2 6.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 1.7 GO:1900094 BMP signaling pathway involved in determination of left/right symmetry(GO:0003154) BMP signaling pathway involved in heart jogging(GO:0003303) negative regulation of endodermal cell fate specification(GO:0042664) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) negative regulation of endodermal cell differentiation(GO:1903225)
0.2 31.2 GO:0001756 somitogenesis(GO:0001756)
0.2 55.5 GO:0006954 inflammatory response(GO:0006954)
0.2 1.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 1.4 GO:0019859 thymine catabolic process(GO:0006210) valine catabolic process(GO:0006574) thymine metabolic process(GO:0019859)
0.2 1.3 GO:0033146 regulation of intracellular steroid hormone receptor signaling pathway(GO:0033143) regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.2 0.9 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 1.8 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 6.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 4.8 GO:0006094 gluconeogenesis(GO:0006094)
0.2 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 11.6 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.2 3.7 GO:0007032 endosome organization(GO:0007032)
0.2 9.8 GO:1990266 granulocyte migration(GO:0097530) neutrophil migration(GO:1990266)
0.2 2.1 GO:0030878 thyroid gland development(GO:0030878)
0.2 0.6 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2 6.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 3.5 GO:0030259 lipid glycosylation(GO:0030259)
0.2 1.2 GO:0001840 neural plate development(GO:0001840)
0.2 5.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 0.4 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 9.5 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.2 1.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 1.1 GO:0071347 interleukin-1-mediated signaling pathway(GO:0070498) cellular response to interleukin-1(GO:0071347)
0.2 3.7 GO:0032438 melanosome organization(GO:0032438)
0.2 7.4 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.2 9.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.2 3.6 GO:0032506 cytokinetic process(GO:0032506)
0.2 5.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 1.1 GO:0032218 riboflavin transport(GO:0032218)
0.2 1.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.9 GO:0060036 notochord cell vacuolation(GO:0060036)
0.2 1.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.5 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.2 1.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 2.6 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.2 0.5 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 2.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.2 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.7 GO:0051601 exocyst localization(GO:0051601)
0.2 1.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 1.5 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 6.2 GO:0032456 endocytic recycling(GO:0032456)
0.2 0.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 1.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.2 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.2 1.8 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 2.7 GO:0007520 myoblast fusion(GO:0007520)
0.2 3.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 2.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 4.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 0.8 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 3.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 2.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.8 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.1 0.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.9 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 14.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 5.6 GO:0071391 response to estrogen(GO:0043627) cellular response to estrogen stimulus(GO:0071391)
0.1 0.6 GO:0097535 lymphoid progenitor cell differentiation(GO:0002320) lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 5.3 GO:0030217 T cell differentiation(GO:0030217)
0.1 4.4 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.6 GO:0007172 signal complex assembly(GO:0007172)
0.1 2.8 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.1 0.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 5.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.9 GO:0046620 regulation of organ growth(GO:0046620)
0.1 8.7 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.7 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 4.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 2.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.9 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 3.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 2.7 GO:0038127 ERBB signaling pathway(GO:0038127)
0.1 1.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.7 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.0 GO:0090660 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 2.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 3.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 6.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.1 3.1 GO:0001878 response to yeast(GO:0001878) response to fungus(GO:0009620)
0.1 1.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.6 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.1 1.3 GO:0032094 response to food(GO:0032094)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 3.4 GO:0003146 heart jogging(GO:0003146)
0.1 0.5 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 1.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 3.2 GO:0032543 mitochondrial translation(GO:0032543)
0.1 6.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 1.0 GO:0090329 regulation of DNA-dependent DNA replication(GO:0090329)
0.1 0.5 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.1 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 2.5 GO:0042098 T cell proliferation(GO:0042098) regulation of T cell proliferation(GO:0042129)
0.1 1.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.8 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.1 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 1.2 GO:0019835 cytolysis(GO:0019835)
0.1 2.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 2.1 GO:0019432 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.1 1.4 GO:0007634 optokinetic behavior(GO:0007634)
0.1 6.1 GO:0021782 glial cell development(GO:0021782)
0.1 10.7 GO:0006869 lipid transport(GO:0006869)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.5 GO:0030183 B cell differentiation(GO:0030183)
0.1 20.2 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 2.3 GO:0046033 AMP metabolic process(GO:0046033)
0.1 6.1 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.1 0.9 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 0.9 GO:0006298 mismatch repair(GO:0006298)
0.1 2.8 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 6.1 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 3.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 2.1 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 6.8 GO:0007283 spermatogenesis(GO:0007283)
0.1 0.9 GO:0097324 melanocyte migration(GO:0097324)
0.1 2.2 GO:0001894 tissue homeostasis(GO:0001894)
0.1 2.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 1.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 2.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.4 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 0.7 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 1.5 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 2.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.1 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 2.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 5.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.6 GO:0001573 ganglioside metabolic process(GO:0001573) ganglioside catabolic process(GO:0006689)
0.0 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 11.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 2.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.0 GO:0009615 response to virus(GO:0009615)
0.0 1.1 GO:0002440 production of molecular mediator of immune response(GO:0002440)
0.0 4.8 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.4 GO:0003159 morphogenesis of an endothelium(GO:0003159) endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 20.1 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 23.2 GO:0010941 regulation of cell death(GO:0010941)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 2.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.2 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 3.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.0 GO:0061053 somite development(GO:0061053)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 2.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.8 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.3 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
0.0 0.3 GO:0042159 protein depalmitoylation(GO:0002084) lipoprotein catabolic process(GO:0042159) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0072028 nephron morphogenesis(GO:0072028)
0.0 0.8 GO:0050817 coagulation(GO:0050817)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 6.9 GO:0043043 translation(GO:0006412) peptide biosynthetic process(GO:0043043)
0.0 1.0 GO:0045087 innate immune response(GO:0045087)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 6.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 3.3 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.2 GO:0030206 chondroitin sulfate metabolic process(GO:0030204) chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.6 GO:0045010 actin nucleation(GO:0045010)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 29.1 GO:0044611 nuclear pore inner ring(GO:0044611)
4.5 49.7 GO:0045095 keratin filament(GO:0045095)
3.5 14.2 GO:0008290 F-actin capping protein complex(GO:0008290)
3.5 17.7 GO:0097433 dense body(GO:0097433)
3.2 12.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
3.0 56.8 GO:0030057 desmosome(GO:0030057)
2.8 8.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
2.6 7.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
2.5 34.3 GO:0000815 ESCRT III complex(GO:0000815)
2.2 41.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
2.1 31.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.9 11.5 GO:1902636 kinociliary basal body(GO:1902636)
1.9 15.3 GO:0001772 immunological synapse(GO:0001772)
1.9 5.7 GO:0098536 deuterosome(GO:0098536)
1.5 8.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.4 8.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.4 15.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.2 6.2 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
1.1 15.9 GO:0042555 MCM complex(GO:0042555)
1.0 10.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.9 5.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.9 9.7 GO:0035101 FACT complex(GO:0035101)
0.9 9.5 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.8 6.5 GO:0061700 GATOR2 complex(GO:0061700)
0.8 11.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.7 70.7 GO:0005882 intermediate filament(GO:0005882)
0.7 2.9 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.7 13.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.7 3.4 GO:0018444 translation release factor complex(GO:0018444)
0.7 4.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.7 9.2 GO:0048179 activin receptor complex(GO:0048179)
0.6 28.9 GO:0031941 filamentous actin(GO:0031941)
0.6 7.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 8.5 GO:0070187 telosome(GO:0070187)
0.6 13.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.6 70.3 GO:0016459 myosin complex(GO:0016459)
0.6 7.7 GO:0002102 podosome(GO:0002102)
0.5 11.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 67.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.5 46.2 GO:0005604 basement membrane(GO:0005604)
0.5 12.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 29.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.5 5.3 GO:0030904 retromer complex(GO:0030904)
0.5 9.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.5 28.3 GO:0031901 early endosome membrane(GO:0031901)
0.5 2.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.5 7.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5 1.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 4.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 26.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 2.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 21.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 22.4 GO:0005884 actin filament(GO:0005884)
0.3 4.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.3 0.9 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 3.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 12.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.3 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 10.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 22.8 GO:0030018 Z disc(GO:0030018)
0.3 23.4 GO:0005769 early endosome(GO:0005769)
0.3 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 1.3 GO:0000811 GINS complex(GO:0000811)
0.2 1.0 GO:0044609 DBIRD complex(GO:0044609)
0.2 4.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 2.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 6.7 GO:0005839 proteasome core complex(GO:0005839)
0.2 3.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 4.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 12.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.2 54.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 0.9 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 4.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 13.8 GO:0030027 lamellipodium(GO:0030027)
0.2 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 2.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 43.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 49.9 GO:0000785 chromatin(GO:0000785)
0.2 17.1 GO:0016324 apical plasma membrane(GO:0016324)
0.2 38.4 GO:0005764 lysosome(GO:0005764)
0.2 7.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 7.2 GO:0016342 catenin complex(GO:0016342)
0.1 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 2.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 10.3 GO:0005581 collagen trimer(GO:0005581)
0.1 46.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 5.6 GO:0016605 PML body(GO:0016605)
0.1 10.6 GO:0005814 centriole(GO:0005814)
0.1 6.2 GO:0005811 lipid particle(GO:0005811)
0.1 5.2 GO:0005770 late endosome(GO:0005770)
0.1 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 5.6 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 2.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 5.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.3 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.2 GO:0030496 midbody(GO:0030496)
0.1 0.8 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 14.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 8.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 4.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 5.2 GO:0005643 nuclear pore(GO:0005643)
0.1 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 10.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 104.0 GO:0005829 cytosol(GO:0005829)
0.1 1.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 88.2 GO:0005615 extracellular space(GO:0005615)
0.1 6.9 GO:0005925 focal adhesion(GO:0005925)
0.1 3.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 6.7 GO:0016607 nuclear speck(GO:0016607)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 22.0 GO:0000139 Golgi membrane(GO:0000139)
0.1 3.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 13.9 GO:0005730 nucleolus(GO:0005730)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 4.1 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.9 GO:0005840 ribosome(GO:0005840)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0030139 endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
15.8 63.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
7.4 36.9 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
6.4 31.9 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
6.4 25.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
6.2 43.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
5.7 17.2 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
4.7 23.6 GO:0070412 R-SMAD binding(GO:0070412)
4.4 13.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
4.2 12.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
4.1 16.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
4.1 16.2 GO:0097108 hedgehog family protein binding(GO:0097108)
4.0 12.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
3.5 17.7 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
3.5 27.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
3.1 18.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
3.1 15.3 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
3.0 42.1 GO:0008327 methyl-CpG binding(GO:0008327)
2.8 8.4 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
2.8 19.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
2.7 13.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
2.6 18.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
2.2 8.9 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
2.2 17.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
2.1 29.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.1 6.3 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
2.1 6.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
2.0 8.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.0 6.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
2.0 8.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.0 30.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
1.8 7.4 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
1.8 16.5 GO:0045294 alpha-catenin binding(GO:0045294)
1.8 14.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.7 8.5 GO:0070644 vitamin D response element binding(GO:0070644)
1.7 11.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.6 6.4 GO:0031708 endothelin B receptor binding(GO:0031708)
1.6 4.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.5 41.4 GO:0042805 actinin binding(GO:0042805)
1.5 4.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.5 7.5 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
1.5 5.8 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.5 10.2 GO:0070728 leucine binding(GO:0070728)
1.4 8.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.4 12.7 GO:0016936 galactoside binding(GO:0016936)
1.4 39.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.4 4.1 GO:0004904 interferon receptor activity(GO:0004904)
1.3 17.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.3 3.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.3 6.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
1.2 12.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
1.2 10.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
1.2 8.4 GO:0019809 spermidine binding(GO:0019809)
1.2 15.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
1.1 5.7 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
1.1 3.4 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
1.1 6.8 GO:0016361 activin receptor activity, type I(GO:0016361)
1.0 29.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.0 9.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.0 25.3 GO:0005112 Notch binding(GO:0005112)
1.0 9.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.0 3.0 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.0 12.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.0 2.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.0 25.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.0 8.6 GO:0004586 ornithine decarboxylase activity(GO:0004586)
1.0 11.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
1.0 21.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 9.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.9 3.7 GO:0003796 lysozyme activity(GO:0003796)
0.9 12.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.9 8.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.9 20.5 GO:0015926 glucosidase activity(GO:0015926)
0.9 14.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 29.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.8 3.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.8 23.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.8 12.5 GO:0005080 protein kinase C binding(GO:0005080)
0.8 7.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 4.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 3.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.7 3.0 GO:0019215 intermediate filament binding(GO:0019215)
0.7 10.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 3.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.7 8.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.7 22.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 9.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.7 11.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.7 4.0 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.7 8.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.7 10.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.7 2.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.6 2.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 15.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.6 18.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.6 6.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 17.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.6 16.3 GO:0015248 sterol transporter activity(GO:0015248)
0.6 7.2 GO:0031720 haptoglobin binding(GO:0031720)
0.6 4.8 GO:0036122 BMP binding(GO:0036122)
0.6 5.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.6 8.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.6 5.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.6 5.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.6 3.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.6 2.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 3.9 GO:0004630 phospholipase D activity(GO:0004630)
0.5 14.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 1.6 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.5 1.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.5 7.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 2.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.5 6.8 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.5 2.6 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.5 21.1 GO:0005109 frizzled binding(GO:0005109)
0.5 4.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 4.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 15.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.5 13.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 12.8 GO:0016289 CoA hydrolase activity(GO:0016289)
0.5 3.8 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.5 15.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5 2.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 2.7 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.5 1.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 6.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 4.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.4 3.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 1.8 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.4 1.7 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.4 3.9 GO:0004359 glutaminase activity(GO:0004359)
0.4 5.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.4 8.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 9.2 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.4 2.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 3.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 3.2 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.4 8.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.4 9.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 17.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 8.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 2.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 1.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4 4.5 GO:0005158 insulin receptor binding(GO:0005158)
0.4 48.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 7.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.4 12.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.4 1.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.4 6.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 9.2 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.3 4.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 3.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 6.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 2.9 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.3 4.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 8.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 5.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 3.1 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 4.2 GO:0048185 activin binding(GO:0048185)
0.3 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 2.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 0.9 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.3 5.1 GO:0035497 cAMP response element binding(GO:0035497)
0.3 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.3 24.9 GO:0045296 cadherin binding(GO:0045296)
0.3 1.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.3 1.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.3 14.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 2.4 GO:0043515 kinetochore binding(GO:0043515)
0.3 2.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 5.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 20.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 9.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 10.0 GO:0019956 chemokine binding(GO:0019956)
0.2 1.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 2.2 GO:0030332 cyclin binding(GO:0030332)
0.2 8.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 12.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 3.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 8.7 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.2 0.7 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.4 GO:0015616 DNA translocase activity(GO:0015616)
0.2 94.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 3.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 1.3 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 43.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 25.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 5.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.2 1.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 12.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 1.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 20.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.8 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.2 1.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 3.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 1.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 10.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.2 37.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 41.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.7 GO:0008494 translation activator activity(GO:0008494)
0.2 1.7 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 2.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 0.9 GO:0043236 laminin binding(GO:0043236)
0.2 1.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 5.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 4.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 2.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 3.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 49.6 GO:0005198 structural molecule activity(GO:0005198)
0.2 1.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 1.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 45.7 GO:0051015 actin filament binding(GO:0051015)
0.2 3.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 4.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.2 1.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 10.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 6.0 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.8 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.5 GO:0048038 quinone binding(GO:0048038)
0.1 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.8 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 2.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 0.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 8.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 7.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 7.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.5 GO:0070513 death domain binding(GO:0070513)
0.1 2.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 1.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.7 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.2 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 21.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.6 GO:0060182 apelin receptor activity(GO:0060182)
0.1 15.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.5 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 7.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 10.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 10.7 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.1 1.9 GO:0010181 FMN binding(GO:0010181)
0.1 3.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.5 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 5.2 GO:0031491 nucleosome binding(GO:0031491)
0.1 2.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.7 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104)
0.1 4.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 4.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.7 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 3.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.2 GO:0043022 ribosome binding(GO:0043022)
0.1 9.3 GO:0015293 symporter activity(GO:0015293)
0.1 0.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 6.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 5.1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 3.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.1 3.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 43.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 1.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 4.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 99.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 7.8 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 4.8 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 2.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.8 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 9.9 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 2.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 7.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.5 GO:0019838 growth factor binding(GO:0019838)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 7.7 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 17.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.7 75.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.7 20.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.7 105.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.1 27.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 7.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.8 13.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.8 6.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 9.7 PID IL3 PATHWAY IL3-mediated signaling events
0.7 8.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 36.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.6 43.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.6 5.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 17.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.5 42.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.5 18.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.5 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 5.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.4 2.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 12.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 16.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.4 9.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 14.3 PID ATR PATHWAY ATR signaling pathway
0.4 3.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 3.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 15.9 PID CMYB PATHWAY C-MYB transcription factor network
0.3 5.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 2.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 10.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.3 4.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 5.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 3.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 1.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 3.0 ST GA12 PATHWAY G alpha 12 Pathway
0.2 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 4.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 3.3 PID BCR 5PATHWAY BCR signaling pathway
0.2 6.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 2.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 3.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 2.5 PID IL1 PATHWAY IL1-mediated signaling events
0.2 1.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 5.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 14.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID AURORA B PATHWAY Aurora B signaling
0.1 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
3.2 41.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
3.0 62.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.8 25.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.8 31.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.6 9.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.4 20.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.3 5.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
1.2 23.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
1.2 3.7 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
1.2 3.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.1 15.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 10.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.1 8.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.0 15.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
1.0 1.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
1.0 17.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.9 22.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.8 30.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.7 5.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.7 6.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 7.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.7 15.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7 49.6 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.7 10.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.6 12.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.6 8.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 7.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 6.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.6 11.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 4.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 13.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 29.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.5 15.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.5 10.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.5 3.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 10.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.5 5.0 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.4 18.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 3.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 15.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 3.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 9.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 25.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.4 3.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.3 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 1.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 34.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 8.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 4.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 4.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 6.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 5.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.2 4.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 3.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 4.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.2 4.7 REACTOME KINESINS Genes involved in Kinesins
0.2 7.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 7.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 5.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2 2.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 4.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 4.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.2 4.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 0.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 21.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2 15.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 9.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 6.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.5 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.1 1.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 9.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 8.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 2.9 REACTOME TRANSLATION Genes involved in Translation
0.1 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.7 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.1 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.1 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 3.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import