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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox21b

Z-value: 1.28

Motif logo

Transcription factors associated with sox21b

Gene Symbol Gene ID Gene Info
ENSDARG00000008540 SRY-box transcription factor 21b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox21bdr11_v1_chr9_+_53276356_532763560.581.3e-09Click!

Activity profile of sox21b motif

Sorted Z-values of sox21b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_54387550 22.62 ENSDART00000097388
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr16_+_37582872 20.78 ENSDART00000169331
adhesion G protein-coupled receptor B1a
chr8_-_49431939 20.71 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
synaptophysin b
chr14_+_49135264 19.86 ENSDART00000084119
si:ch1073-44g3.1
chr13_-_24448278 16.77 ENSDART00000057584
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr19_-_7450796 16.67 ENSDART00000104750
MLLT11, transcription factor 7 cofactor
chr15_+_28685892 16.54 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr25_-_12203952 15.96 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr7_+_73630751 15.73 ENSDART00000159745
si:dkey-46i9.1
chr25_+_4837915 14.83 ENSDART00000168016
guanine nucleotide binding protein (G protein), beta 5a
chr25_-_19433244 13.36 ENSDART00000154778
microtubule-associated protein 1Ab
chr21_-_42007482 12.79 ENSDART00000075740
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr21_-_42007213 12.79 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr5_+_64732036 12.76 ENSDART00000073950
olfactomedin 1a
chr16_-_42390441 12.08 ENSDART00000148475
chondroitin sulfate proteoglycan 5a
chr5_+_66353750 12.03 ENSDART00000143410
si:ch211-261c8.5
chr20_-_34801181 11.90 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr17_-_36936856 11.25 ENSDART00000010274
ENSDART00000188887
dihydropyrimidinase-like 5a
chr16_-_44399335 10.95 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr19_-_28360033 10.94 ENSDART00000186994
si:dkey-261i16.5
chr15_+_28685625 10.30 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr9_-_6661657 10.12 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
POU class 3 homeobox 3a
chr3_-_21037840 9.93 ENSDART00000002393
RUN domain containing 3Aa
chr12_-_19102736 9.87 ENSDART00000180364
cold shock domain containing C2, RNA binding a
chr5_-_13167097 9.39 ENSDART00000149700
ENSDART00000030213
mitogen-activated protein kinase 1
chr9_+_17971935 9.37 ENSDART00000149736
A kinase (PRKA) anchor protein 11
chr21_+_26389391 9.36 ENSDART00000077197
thymosin, beta
chr20_-_45661049 9.25 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr4_+_5506952 9.24 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr18_+_13837746 9.07 ENSDART00000169552
cadherin 13, H-cadherin (heart)
chr8_-_52473054 9.01 ENSDART00000193658
phytanoyl-CoA 2-hydroxylase interacting protein
chr3_-_50127668 8.75 ENSDART00000062116
claudin k
chr17_+_44780166 8.74 ENSDART00000156260
transmembrane protein 63C
chr14_-_2327825 8.47 ENSDART00000180328
ENSDART00000191135
ENSDART00000114302
ENSDART00000189869
protocadherin 2 alpha b 8
protocadherin 2 alpha a 1
chr10_-_34871737 8.24 ENSDART00000138755
doublecortin-like kinase 1a
chr16_+_37470717 8.16 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adhesion G protein-coupled receptor B1a
chr6_-_46403475 8.13 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr17_+_19630272 7.98 ENSDART00000104895
regulator of G protein signaling 7a
chr11_-_1509773 7.98 ENSDART00000050762
phosphatase and actin regulator 3b
chr5_+_20693724 7.87 ENSDART00000141368
si:ch211-240b21.2
chr12_+_35650321 7.71 ENSDART00000190446

chr18_-_8313686 7.34 ENSDART00000182187
mitogen-activated protein kinase 8 interacting protein 2
chr4_+_75200467 7.33 ENSDART00000122593

chr1_-_625875 7.30 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr14_+_34966598 7.27 ENSDART00000004550
ring finger protein 145a
chr12_-_15002563 7.26 ENSDART00000108852
ENSDART00000141909
protein kinase, membrane associated tyrosine/threonine 1
chr14_+_35405518 7.24 ENSDART00000171565
zinc finger and BTB domain containing 3
chr2_+_31833997 7.22 ENSDART00000066788
ependymin related 1
chr1_+_26445615 7.15 ENSDART00000180810
GTPase activating protein (SH3 domain) binding protein 2
chr25_+_29662411 7.03 ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr11_-_25733910 7.01 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr8_-_31403938 7.01 ENSDART00000159168
NIM1 serine/threonine protein kinase
chr7_-_35708450 6.95 ENSDART00000193886
iroquois homeobox 5a
chr14_-_2217285 6.89 ENSDART00000157949
ENSDART00000166150
ENSDART00000054891
ENSDART00000183268
protocadherin 2 alpha b2
protocadherin 2 alpha b2
chr7_+_72012397 6.75 ENSDART00000011303
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2
chr2_-_32356539 6.65 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr23_-_7125494 6.41 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr23_+_21482571 6.40 ENSDART00000187368
si:dkey-1c11.1
chr14_-_4273396 6.37 ENSDART00000127318
FERM and PDZ domain containing 1b
chr7_-_71434298 6.35 ENSDART00000180507
leucine-rich repeat LGI family, member 2a
chr5_-_67895656 6.30 ENSDART00000158917
abhydrolase domain containing 10a
chr12_+_41991635 6.23 ENSDART00000186161
ENSDART00000192510
transcription elongation regulator 1 like
chr23_+_6795531 6.20 ENSDART00000092131
si:ch211-117c9.5
chr1_+_26444986 6.20 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr5_+_66353589 6.14 ENSDART00000138246
si:ch211-261c8.5
chr17_-_44249720 6.04 ENSDART00000156648
orthodenticle homeobox 2b
chr6_-_35310224 5.90 ENSDART00000148997
nitric oxide synthase 1 (neuronal) adaptor protein a
chr14_-_49896795 5.77 ENSDART00000168142
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like
chr23_-_21946603 5.72 ENSDART00000148120
ENSDART00000184524
eph receptor B2a
chr8_-_1838315 5.68 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr14_+_44545092 5.43 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr24_+_8904741 5.22 ENSDART00000140924
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_+_1835940 5.17 ENSDART00000167372
protein tyrosine kinase 2aa
chr13_-_11035420 5.11 ENSDART00000108709
centrosomal protein 170Aa
chr24_-_24271629 5.11 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr19_-_41069573 5.06 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr18_+_29950233 5.03 ENSDART00000146431
ATM interactor
chr5_+_21144269 5.00 ENSDART00000028087
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr18_+_924949 4.99 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr1_+_34295925 4.89 ENSDART00000075584
potassium channel tetramerisation domain containing 12.2
chr15_-_47857687 4.88 ENSDART00000098982
ENSDART00000151594
H3 histone, family 3B.1
chr17_+_14425219 4.81 ENSDART00000153994
coiled-coil domain containing 175
chr17_+_24320861 4.77 ENSDART00000179858
orthodenticle homeobox 1
chr9_+_13733468 4.69 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abl-interactor 2a
chr22_+_12798569 4.62 ENSDART00000005720
signal transducer and activator of transcription 1a
chr5_-_64865521 4.54 ENSDART00000043397
ENSDART00000145831
si:ch211-236k19.4
chr13_+_50151407 4.45 ENSDART00000031858
G protein-coupled receptor 137Ba
chr1_+_41666611 4.41 ENSDART00000145789
F-box protein 41
chr7_+_26466826 4.39 ENSDART00000058908
mannose-P-dolichol utilization defect 1b
chr5_+_27137473 4.38 ENSDART00000181833
unc-5 netrin receptor Db
chr8_+_2487883 4.34 ENSDART00000101841
dynein, light chain, LC8-type 1
chr8_+_25913787 4.31 ENSDART00000190257
ENSDART00000062515
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H
chr16_-_37372613 4.26 ENSDART00000124090
si:ch211-208k15.1
chr11_-_42980535 4.26 ENSDART00000181160
ENSDART00000192064

chr5_-_28767573 4.05 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr23_-_42810664 3.99 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr21_+_21263988 3.91 ENSDART00000089651
ENSDART00000108978
coiled-coil domain containing 61
chr7_-_40122139 3.80 ENSDART00000173982
si:ch73-174h16.5
chr6_-_48473395 3.72 ENSDART00000185096
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr13_+_25455319 3.63 ENSDART00000145948
polycystic kidney disease 2-like 1
chr4_+_5333988 3.63 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
APEX nuclease (multifunctional DNA repair enzyme) 1
chr9_+_34641237 3.63 ENSDART00000133996
short stature homeobox
chr22_+_2300484 3.58 ENSDART00000106503
zinc finger protein 1180
chr5_-_15494164 3.58 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
TAO kinase 3a
chr21_-_29117670 3.49 ENSDART00000124327
hepatitis A virus cellular receptor 2
chr25_-_28668776 3.43 ENSDART00000126490
formin binding protein 4
chr13_-_39399967 3.33 ENSDART00000190791
ENSDART00000136267
solute carrier family 35, member F3b
chr17_+_28533102 3.29 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr12_+_19348538 3.26 ENSDART00000066388
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr3_-_30488063 3.25 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr5_-_33255759 3.25 ENSDART00000085531
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr16_-_8342749 3.19 ENSDART00000028108
dopa decarboxylase
chr21_-_2261720 3.16 ENSDART00000170161
si:ch73-299h12.2
chr8_+_2487250 3.11 ENSDART00000081325
dynein, light chain, LC8-type 1
chr23_+_6795709 3.04 ENSDART00000149136
si:ch211-117c9.5
chr22_+_17399124 3.04 ENSDART00000145769
RAB GTPase activating protein 1-like
chr19_-_32940040 2.96 ENSDART00000179947
antizyme inhibitor 1b
chr17_+_15882533 2.95 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr12_+_15002757 2.95 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr13_-_48764180 2.92 ENSDART00000167157
si:ch1073-266p11.2
chr23_+_5565261 2.91 ENSDART00000059307
ENSDART00000169904
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr11_+_36231248 2.91 ENSDART00000131104
si:ch211-213o11.11
chr21_+_39423974 2.90 ENSDART00000031470
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr5_-_55623443 2.85 ENSDART00000005671
ENSDART00000176341
heterogeneous nuclear ribonucleoprotein K, like
chr13_-_5568928 2.79 ENSDART00000192679
Meis homeobox 1 b
chr8_+_39511932 2.77 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr5_-_31035198 2.76 ENSDART00000086534
cytochrome b5 domain containing 2
chr19_-_42045372 2.71 ENSDART00000144275
trio Rho guanine nucleotide exchange factor a
chr13_-_50247689 2.68 ENSDART00000034541
G patch domain containing 11
chr9_-_23118350 2.60 ENSDART00000020884
LY6/PLAUR domain containing 6
chr19_-_38872650 2.57 ENSDART00000146641
adhesion G protein-coupled receptor B2
chr23_-_27050083 2.57 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
chr13_-_41546779 2.56 ENSDART00000163331
protocadherin-related 15a
chr15_+_879897 2.56 ENSDART00000185066
ENSDART00000179840
si:dkey-7i4.9
si:dkey-77f5.13
chr7_+_24023653 2.55 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr13_-_19799824 2.45 ENSDART00000058032
family with sequence similarity 204, member A
chr5_-_33825465 2.43 ENSDART00000110645
DAB2 interacting protein b
chr8_-_13184989 2.40 ENSDART00000135738
zgc:194990
chr11_-_26362294 2.39 ENSDART00000184654
ENSDART00000115037
forkhead box J3
chr8_-_50981175 2.38 ENSDART00000004065
zgc:91909
chr13_-_18195942 2.32 ENSDART00000079902
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr10_+_35275965 2.27 ENSDART00000077404
P450 (cytochrome) oxidoreductase a
chr22_-_38480186 2.27 ENSDART00000171704
heme-binding protein soul4
chr12_-_37734973 2.21 ENSDART00000140353
sidekick cell adhesion molecule 2b
chr14_+_28281744 2.19 ENSDART00000173292
midline 2
chr8_+_16726386 2.17 ENSDART00000144621
small integral membrane protein 15
chr16_+_49647402 2.16 ENSDART00000015694
ENSDART00000132547
RAB5A, member RAS oncogene family, b
chr21_-_25685739 2.15 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr2_-_1548330 2.15 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr2_-_17947389 2.10 ENSDART00000190089
ENSDART00000191872
ENSDART00000184039
ENSDART00000179791
protein tyrosine phosphatase, receptor type, f, b
chr2_-_24981356 2.08 ENSDART00000111212
NCK adaptor protein 1a
chr16_-_38067952 2.05 ENSDART00000114266
pleckstrin homology domain containing, family O member 1b
chr5_+_13521081 2.00 ENSDART00000171975
si:ch211-230g14.6
chr4_-_27129697 1.99 ENSDART00000131240
zinc finger, BED-type containing 4
chr2_+_24374305 1.99 ENSDART00000022379
nuclear receptor subfamily 2, group F, member 6a
chr18_+_6039141 1.98 ENSDART00000138972
si:ch73-386h18.1
chr13_-_43637371 1.97 ENSDART00000127930
ENSDART00000084474
family with sequence similarity 160, member B1
chr18_+_19972853 1.95 ENSDART00000180071
SKI family transcriptional corepressor 1b
chr24_-_32173754 1.90 ENSDART00000048633
tRNA aspartic acid methyltransferase 1
chr20_-_26420939 1.88 ENSDART00000110883
A kinase (PRKA) anchor protein 12b
chr11_-_18557929 1.87 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
death inducer-obliterator 1
chr18_+_9493720 1.84 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr17_-_22010668 1.83 ENSDART00000031998
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr8_+_18010568 1.78 ENSDART00000121984
single stranded DNA binding protein 3b
chr2_-_31791633 1.78 ENSDART00000180662
reticulophagy regulator 1
chr17_+_23146976 1.72 ENSDART00000114212
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_34522249 1.70 ENSDART00000158616
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr12_+_4225199 1.66 ENSDART00000042277
mitogen-activated protein kinase 7
chr4_+_61693986 1.61 ENSDART00000162832
zinc finger protein 1104
chr10_-_20453995 1.61 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
chr5_-_35161877 1.60 ENSDART00000139673
FCH domain only 2
chr10_-_8197049 1.60 ENSDART00000129467
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr5_+_35744623 1.58 ENSDART00000148213
ENSDART00000076627
Yip1 domain family, member 6
chr24_-_23784701 1.58 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr12_+_499881 1.57 ENSDART00000167527
myosin phosphatase Rho interacting protein
chr12_+_25097754 1.56 ENSDART00000050070
phosphatidylinositol glycan anchor biosynthesis, class F
chr4_-_13567387 1.56 ENSDART00000132971
ENSDART00000102010
Mdm1 nuclear protein homolog (mouse)
chr19_+_30450125 1.51 ENSDART00000073704
si:ch211-215a10.4
chr12_-_20796430 1.49 ENSDART00000064339
NME/NM23 nucleoside diphosphate kinase 2a
chr4_+_17424855 1.49 ENSDART00000162204
ENSDART00000101198
RecQ helicase-like
chr7_+_828289 1.48 ENSDART00000173796
cabz01076234.2
chr18_-_46882056 1.48 ENSDART00000108574
GRAM domain containing 1Bb
chr11_-_23314242 1.44 ENSDART00000182394
KiSS-1 metastasis-suppressor
chr13_+_23132666 1.42 ENSDART00000164639
sorbin and SH3 domain containing 1
chr6_+_6802582 1.41 ENSDART00000189422
D-tyrosyl-tRNA deacylase 1
chr17_+_37215820 1.33 ENSDART00000104009
solute carrier family 30 (zinc transporter), member 1b
chr19_+_2279051 1.33 ENSDART00000182103
integrin, beta 8
chr3_+_60716904 1.29 ENSDART00000168280
forkhead box J1a
chr3_-_60142530 1.27 ENSDART00000153247
si:ch211-120g10.1
chr8_+_39998467 1.23 ENSDART00000073782
ENSDART00000134452
gamma-glutamyltransferase 5a
chr8_-_52859301 1.20 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr10_-_26430168 1.20 ENSDART00000128894
dachsous cadherin-related 1b
chr15_+_887032 1.19 ENSDART00000156395
si:dkey-7i4.9
chr6_-_52235118 1.18 ENSDART00000191243
translocase of outer mitochondrial membrane 34
chr20_-_16453602 1.16 ENSDART00000006443
general transcription factor IIA, 1
chr17_+_8175998 1.14 ENSDART00000131200
myc target 1b
chr10_-_15963903 1.13 ENSDART00000142357
si:dkey-3h23.3
chr13_+_11550454 1.12 ENSDART00000034935
ENSDART00000166908
desumoylating isopeptidase 2
chr3_-_32873641 1.11 ENSDART00000075277
zgc:113090
chr6_-_57539141 1.10 ENSDART00000156967
itchy E3 ubiquitin protein ligase a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox21b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 25.6 GO:0070208 protein heterotrimerization(GO:0070208)
3.3 16.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
2.3 9.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
2.3 9.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.7 9.9 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
1.5 4.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.4 12.8 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
1.2 7.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.2 12.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.1 9.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
1.1 3.3 GO:0021611 facial nerve formation(GO:0021611)
1.0 5.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.0 16.0 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.9 22.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.9 3.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.8 28.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.7 2.9 GO:0051012 microtubule sliding(GO:0051012)
0.7 5.4 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.6 4.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 1.9 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.6 11.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.6 4.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.6 2.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.6 5.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.5 3.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.5 25.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 7.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.5 8.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 11.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 3.0 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.5 12.2 GO:0007634 optokinetic behavior(GO:0007634)
0.4 1.3 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.4 4.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.4 2.6 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.4 1.2 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.4 3.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.4 2.9 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.4 4.7 GO:0007172 signal complex assembly(GO:0007172)
0.4 4.6 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.4 1.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3 1.3 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 6.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 26.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 2.2 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 2.9 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.3 2.0 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.2 4.0 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.2 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 8.7 GO:0003094 glomerular filtration(GO:0003094)
0.2 2.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 7.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.2 1.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 5.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 2.6 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.2 0.4 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 6.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 4.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 1.7 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.2 2.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 8.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.8 GO:0061709 reticulophagy(GO:0061709)
0.2 1.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 9.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 3.6 GO:0080111 DNA demethylation(GO:0080111)
0.2 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.0 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 1.0 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 3.9 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 1.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.8 GO:0036268 swimming(GO:0036268)
0.1 1.1 GO:0046548 retinal rod cell development(GO:0046548)
0.1 3.2 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 6.1 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 0.4 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 3.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 2.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 1.4 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 1.2 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.8 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 5.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 18.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.2 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.6 GO:0030282 bone mineralization(GO:0030282)
0.1 3.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 1.0 GO:0045116 protein neddylation(GO:0045116)
0.1 2.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 7.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 9.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 0.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.0 GO:2000404 regulation of T cell migration(GO:2000404)
0.1 1.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 9.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 3.4 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0033292 T-tubule organization(GO:0033292)
0.0 2.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 6.2 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 1.1 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 3.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 22.1 GO:0006886 intracellular protein transport(GO:0006886)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:0043200 response to amino acid(GO:0043200) cellular response to amino acid stimulus(GO:0071230)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 32.7 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.7 GO:0042181 ketone biosynthetic process(GO:0042181)
0.0 0.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.1 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.8 28.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.7 2.9 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.7 5.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 2.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.5 7.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 7.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 11.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.4 20.7 GO:0048786 presynaptic active zone(GO:0048786)
0.4 3.9 GO:0034451 centriolar satellite(GO:0034451)
0.3 1.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 20.8 GO:0031201 SNARE complex(GO:0031201)
0.3 1.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 1.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 16.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 28.9 GO:0014069 postsynaptic density(GO:0014069)
0.2 10.3 GO:0016342 catenin complex(GO:0016342)
0.2 2.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 5.5 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 1.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 2.6 GO:0070187 telosome(GO:0070187)
0.2 0.3 GO:0016011 dystroglycan complex(GO:0016011)
0.1 2.6 GO:0032420 stereocilium(GO:0032420)
0.1 13.4 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 4.7 GO:0030175 filopodium(GO:0030175)
0.1 0.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 16.0 GO:0030424 axon(GO:0030424)
0.1 19.4 GO:0043005 neuron projection(GO:0043005)
0.1 2.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.8 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 26.4 GO:0045202 synapse(GO:0045202)
0.1 7.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 5.4 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.7 GO:0005925 focal adhesion(GO:0005925)
0.0 2.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 4.9 GO:0000786 nucleosome(GO:0000786)
0.0 18.2 GO:0005815 microtubule organizing center(GO:0005815)
0.0 4.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 2.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.0 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 18.3 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 31.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
2.7 16.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.8 25.6 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.2 5.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.0 14.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
1.0 5.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.9 11.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.8 5.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 5.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.7 3.6 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.6 3.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 2.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.6 20.3 GO:0004707 MAP kinase activity(GO:0004707)
0.5 20.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 7.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.5 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.5 3.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.5 1.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.5 9.4 GO:0003785 actin monomer binding(GO:0003785)
0.4 4.4 GO:0005042 netrin receptor activity(GO:0005042)
0.4 2.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 2.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 5.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 12.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.4 4.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 1.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.4 11.3 GO:0051018 protein kinase A binding(GO:0051018)
0.3 5.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 6.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.3 4.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 3.7 GO:0070840 dynein complex binding(GO:0070840)
0.2 7.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 8.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 3.7 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 0.7 GO:0000035 acyl binding(GO:0000035)
0.2 5.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 3.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 11.0 GO:0044325 ion channel binding(GO:0044325)
0.2 8.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 0.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 1.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 3.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0043531 ADP binding(GO:0043531)
0.1 40.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 5.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 10.3 GO:0045296 cadherin binding(GO:0045296)
0.1 18.0 GO:0015293 symporter activity(GO:0015293)
0.1 9.4 GO:0008201 heparin binding(GO:0008201)
0.1 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 3.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 2.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 29.1 GO:0015631 tubulin binding(GO:0015631)
0.1 1.3 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1 1.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 4.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 1.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 6.8 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 4.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 3.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 4.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 19.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 17.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 8.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.7 9.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 7.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 5.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 3.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 18.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.7 25.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.3 5.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.8 6.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.7 7.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 16.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 3.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 7.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 9.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 3.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 3.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 2.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 1.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 5.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 7.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events