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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox19a+sox2

Z-value: 3.27

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Transcription factors associated with sox19a+sox2

Gene Symbol Gene ID Gene Info
ENSDARG00000010770 SRY-box transcription factor 19a
ENSDARG00000070913 SRY-box transcription factor 2
ENSDARG00000110497 SRY-box transcription factor 19a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox2dr11_v1_chr22_-_37349967_373499670.853.1e-27Click!
sox19adr11_v1_chr5_-_24201437_242014370.672.3e-13Click!

Activity profile of sox19a+sox2 motif

Sorted Z-values of sox19a+sox2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17745345 70.77 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
chr11_+_25735478 48.64 ENSDART00000103566
si:dkey-183j2.10
chr6_-_43092175 43.92 ENSDART00000084389
leucine rich repeat neuronal 1
chr11_+_35364445 41.88 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr14_-_33872092 41.67 ENSDART00000111903
si:ch73-335m24.2
chr2_-_21082695 41.52 ENSDART00000032502
nebulette
chr6_+_27146671 38.43 ENSDART00000156792
kinesin family member 1Aa
chr19_-_21832441 38.29 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr2_+_3472832 36.85 ENSDART00000115278
connexin 47.1
chr17_+_15535501 32.87 ENSDART00000002932
myristoylated alanine-rich protein kinase C substrate b
chr9_+_35901554 31.43 ENSDART00000005086
ATPase Na+/K+ transporting subunit alpha 1b
chr7_-_24472991 31.36 ENSDART00000121684
N-acetyltransferase 8-like
chr4_-_27301356 31.19 ENSDART00000100444
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr7_-_26408472 30.62 ENSDART00000111494
galactose-3-O-sulfotransferase 4
chr8_+_16004551 30.15 ENSDART00000165141
ELAV like neuron-specific RNA binding protein 4
chr19_+_43017628 29.45 ENSDART00000182608
ENSDART00000015632
sodium/potassium transporting ATPase interacting 1
chr16_+_34523515 29.40 ENSDART00000041007
stathmin 1b
chr24_-_33756003 29.35 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr16_+_25316973 29.08 ENSDART00000086409
dynein, cytoplasmic 1, intermediate chain 1
chr6_-_35487413 28.75 ENSDART00000102461
regulator of G protein signaling 8
chr9_+_42066030 28.36 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr16_+_14029283 27.64 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr21_+_13861589 27.08 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr16_-_27640995 26.39 ENSDART00000019658
NAC alpha domain containing
chr20_+_35382482 26.27 ENSDART00000135284
visinin-like 1a
chr5_-_6377865 25.63 ENSDART00000031775
zgc:73226
chr24_+_25069609 25.60 ENSDART00000115165
APC membrane recruitment protein 2
chr9_+_2393764 25.29 ENSDART00000172624
chimerin 1
chr16_-_6821927 25.19 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr25_-_204019 25.18 ENSDART00000188440
ENSDART00000191735

chr22_+_5106751 25.06 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr6_-_11780070 24.71 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr9_+_30108641 24.68 ENSDART00000060174
jagunal homolog 1a
chr19_+_43017931 24.54 ENSDART00000132213
sodium/potassium transporting ATPase interacting 1
chr1_-_14233815 24.45 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr23_-_30787932 24.36 ENSDART00000135771
myelin transcription factor 1a
chr14_-_36378494 24.20 ENSDART00000058503
glycoprotein M6Aa
chr10_+_21783213 24.14 ENSDART00000168899
protocadherin 1 gamma 33
chr9_-_18743012 24.12 ENSDART00000131626
TSC22 domain family, member 1
chr23_-_21453614 23.97 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr19_-_19339285 23.78 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr13_+_51579851 23.71 ENSDART00000163847
NK6 homeobox 2
chr20_+_18580176 23.36 ENSDART00000185310
si:dkeyp-72h1.1
chr21_+_26389391 23.22 ENSDART00000077197
thymosin, beta
chr10_+_21677058 23.20 ENSDART00000171499
ENSDART00000157516
protocadherin 1 gamma b 2
chr9_-_18742704 22.94 ENSDART00000145401
TSC22 domain family, member 1
chr6_+_3828560 22.52 ENSDART00000185273
ENSDART00000179091
glutamate decarboxylase 1b
chr12_+_33151246 22.32 ENSDART00000162681
RNA binding fox-1 homolog 3a
chr2_-_31301929 22.29 ENSDART00000191992
ENSDART00000190723
adenylate cyclase activating polypeptide 1b
chr3_-_22212764 22.23 ENSDART00000155490
microtubule-associated protein tau b
chr2_+_26179096 22.16 ENSDART00000024662
phospholipid phosphatase related 3a
chr23_-_18286822 22.09 ENSDART00000136672
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr9_-_44295071 21.94 ENSDART00000011837
neuronal differentiation 1
chr24_-_27400017 21.87 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr14_-_1955257 21.49 ENSDART00000193254
protocadherin 2 gamma 5
chr8_+_16004154 21.48 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
ELAV like neuron-specific RNA binding protein 4
chr14_-_32403554 21.02 ENSDART00000172873
ENSDART00000173408
ENSDART00000173114
ENSDART00000185594
ENSDART00000186762
ENSDART00000010982
fibroblast growth factor 13a
chr13_-_31441042 20.99 ENSDART00000076571
reticulon 1a
chr23_+_35708730 20.79 ENSDART00000009277
tubulin, alpha 1a
chr15_+_22311803 20.77 ENSDART00000150182
hepatic and glial cell adhesion molecule a
chr14_-_2361692 20.74 ENSDART00000167696
si:ch73-233f7.4
chr14_-_2285955 20.60 ENSDART00000183928
protocadherin 2 alpha b 9
chr14_-_1958994 20.58 ENSDART00000161783
protocadherin 2 gamma 5
chr7_+_14632157 20.47 ENSDART00000161264
neurotrophic tyrosine kinase, receptor, type 3b
chr2_+_47623202 20.36 ENSDART00000154465
si:ch211-165b10.3
chr15_+_32821392 20.34 ENSDART00000158272
doublecortin-like kinase 1b
chr21_-_42055872 20.32 ENSDART00000144767
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_39619087 20.31 ENSDART00000134822
musashi RNA-binding protein 1
chr10_-_31782616 20.30 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr9_-_54840124 20.26 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr20_+_9828769 20.12 ENSDART00000160480
ENSDART00000053844
ENSDART00000080691
syntaxin binding protein 6 (amisyn), like
chr14_-_2318590 19.81 ENSDART00000192735
protocadherin 2 alpha b 8
chr14_-_2358774 19.73 ENSDART00000164809
si:ch73-233f7.5
chr25_+_31929325 19.39 ENSDART00000181095
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr2_+_24177006 19.38 ENSDART00000132582
microtubule associated protein 4 like
chr14_-_41285392 19.36 ENSDART00000147389
transmembrane protein 35
chr22_-_22416337 19.27 ENSDART00000142947
ENSDART00000089569
calmodulin regulated spectrin-associated protein family, member 2a
chr14_-_33872616 19.26 ENSDART00000162840
si:ch73-335m24.2
chr11_-_37548711 19.18 ENSDART00000127184
bassoon (presynaptic cytomatrix protein) b
chr9_+_29585943 19.03 ENSDART00000185989
ENSDART00000115290
mcf.2 cell line derived transforming sequence-like b
chr13_+_30506781 19.01 ENSDART00000110884
zinc finger, MIZ-type containing 1a
chr18_-_21218851 18.95 ENSDART00000060160
calbindin 2a
chr5_+_37840914 18.89 ENSDART00000097738
pannexin 1b
chr16_+_10318893 18.87 ENSDART00000055380
tubulin, beta 5
chr20_-_20821783 18.69 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
creatine kinase, brain b
chr17_+_23298928 18.63 ENSDART00000153652
zgc:165461
chr20_+_30445971 18.63 ENSDART00000153150
myelin transcription factor 1-like, a
chr5_+_64739762 18.52 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr7_+_23875269 18.51 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr5_-_33460959 18.25 ENSDART00000085636
si:ch211-182d3.1
chr10_-_35542071 18.18 ENSDART00000162139
si:ch211-244c8.4
chr1_+_54911458 17.98 ENSDART00000089603
golgin A7 family, member Ba
chr1_-_45647846 17.97 ENSDART00000186881

chr25_+_37126921 17.86 ENSDART00000124331
si:ch1073-174d20.1
chr21_+_13353263 17.81 ENSDART00000114677
si:ch73-62l21.1
chr14_-_2355833 17.72 ENSDART00000157677
si:ch73-233f7.6
chr23_-_21463788 17.58 ENSDART00000079265
hairy-related 4, tandem duplicate 4
chr9_+_27411502 17.57 ENSDART00000143994
si:dkey-193n17.9
chr23_-_21471022 17.55 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr19_+_12762887 17.54 ENSDART00000139909
melanocortin 5a receptor
chr11_+_26604224 17.49 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynein, light chain, roadblock-type 1
chr23_+_23182037 17.44 ENSDART00000137353
kelch-like family member 17
chr16_-_12173554 17.41 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr20_+_41756996 17.39 ENSDART00000186393
family with sequence similarity 184, member A
chr4_+_3482312 17.27 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr20_+_37661229 17.24 ENSDART00000138539
androgen-induced 1 (H. sapiens)
chr2_-_5942115 17.09 ENSDART00000154489
transmembrane protein 125b
chr8_-_6877390 17.03 ENSDART00000170883
ENSDART00000005321
neurofilament, light polypeptide b
chr2_+_26303627 16.87 ENSDART00000040278
ephrin-A2a
chr5_-_58939460 16.84 ENSDART00000122413
melanoma cell adhesion molecule a
chr24_-_6644734 16.71 ENSDART00000167391
Rho GTPase activating protein 21a
chr5_-_35301800 16.68 ENSDART00000085142
microtubule-associated protein 1B
chr21_-_43043523 16.61 ENSDART00000040169
janus kinase and microtubule interacting protein 2
chr20_+_51312883 16.48 ENSDART00000084186
transmembrane protein 151Ba
chr14_-_2364761 16.37 ENSDART00000167322
si:ch73-233f7.3
chr20_-_48485354 16.36 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr14_-_1990290 16.32 ENSDART00000183382
protocadherin 2 gamma 5
chr14_-_33454595 16.31 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr4_+_12615836 16.27 ENSDART00000003583
LIM domain only 3
chr20_-_27864964 16.25 ENSDART00000153311
synapse differentiation inducing 1-like
chr10_+_39164638 15.89 ENSDART00000188997

chr14_-_2270973 15.89 ENSDART00000180729
protocadherin 2 alpha b 9
chr13_-_43599898 15.87 ENSDART00000084416
ENSDART00000145705
actin binding LIM protein 1a
chr15_-_16070731 15.84 ENSDART00000122099
dynein, light chain, LC8-type 2a
chr13_+_25428677 15.69 ENSDART00000186284
si:dkey-51a16.9
chr7_-_38612230 15.68 ENSDART00000173678
C1q and TNF related 4
chr17_-_15657029 15.53 ENSDART00000153925
fucosyltransferase 9a
chr16_+_5678071 15.41 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
chr17_-_44968177 15.39 ENSDART00000075510
neuroglobin
chr20_-_40319890 15.36 ENSDART00000075112
clavesin 2
chr23_-_14918276 15.28 ENSDART00000179831
ndrg family member 3b
chr13_+_27951688 15.24 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr11_+_23704410 15.09 ENSDART00000112655
neurofascin homolog (chicken) a
chr16_-_16590780 15.07 ENSDART00000059841
si:ch211-257p13.3
chr20_-_31497300 15.04 ENSDART00000046841
SAM and SH3 domain containing 1a
chr11_+_25101220 15.03 ENSDART00000183700
ndrg family member 3a
chr17_+_2063693 15.02 ENSDART00000182349
zgc:162989
chr9_-_18735256 14.91 ENSDART00000143165
TSC22 domain family, member 1
chr3_+_24134418 14.70 ENSDART00000156204
si:ch211-246i5.5
chr15_-_33925851 14.70 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr7_-_52842007 14.65 ENSDART00000182710
microtubule-associated protein 1Aa
chr2_+_26240631 14.60 ENSDART00000129895
paralemmin 1b
chr10_-_22845485 14.60 ENSDART00000079454
vesicle-associated membrane protein 2
chr7_+_49078890 14.59 ENSDART00000067857
beta-1,4-N-acetyl-galactosaminyl transferase 4b
chr5_-_26093945 14.52 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr10_+_18952271 14.51 ENSDART00000146517
dihydropyrimidinase-like 2b
chr13_-_27660955 14.31 ENSDART00000188651
ENSDART00000134494
regulating synaptic membrane exocytosis 1a
chr17_+_6793001 14.30 ENSDART00000030773
forkhead box O3A
chr19_+_30633453 14.29 ENSDART00000052124
family with sequence similarity 49, member A-like
chr21_+_17110598 14.27 ENSDART00000101282
ENSDART00000191864
breakpoint cluster region
chr15_+_36115955 14.23 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr19_+_16032383 14.19 ENSDART00000046530
RAB42, member RAS oncogene family a
chr16_-_15988320 14.14 ENSDART00000160883

chr4_-_14315855 14.12 ENSDART00000133325
neural EGFL like 2b
chr2_+_24177190 13.99 ENSDART00000099546
microtubule associated protein 4 like
chr8_+_25267903 13.98 ENSDART00000093090
adenosine monophosphate deaminase 2b
chr18_-_38088099 13.89 ENSDART00000146120
leucine zipper protein 2
chr19_-_103289 13.88 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr5_-_32323136 13.87 ENSDART00000110804
heat shock protein, alpha-crystallin-related, b15
chr10_+_21559605 13.87 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr4_-_24031924 13.85 ENSDART00000017443
cugbp, Elav-like family member 2
chr14_-_26177156 13.83 ENSDART00000014149
FAT atypical cadherin 2
chr11_+_40649412 13.82 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr2_-_32688905 13.78 ENSDART00000041146
nuclear receptor binding protein 2a
chr17_+_8183393 13.75 ENSDART00000155957
tubby like protein 4b
chr2_-_21170517 13.74 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr5_+_23118470 13.74 ENSDART00000149893
neurite extension and migration factor a
chr18_+_642889 13.73 ENSDART00000189007

chr17_-_16965809 13.72 ENSDART00000153697
neurexin 3a
chr12_+_10115964 13.63 ENSDART00000152369
si:dkeyp-118b1.2
chr13_+_12739283 13.61 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr1_-_25911901 13.61 ENSDART00000109714
ubiquitin specific peptidase 53b
chr21_+_45733871 13.59 ENSDART00000187285
ENSDART00000193018
zgc:77058
chr15_-_33896159 13.59 ENSDART00000159791
myelin associated glycoprotein
chr17_+_12700617 13.53 ENSDART00000191931
stathmin-like 4, like
chr22_-_20309283 13.52 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
chr10_+_21668606 13.48 ENSDART00000185751

chr5_-_29488245 13.46 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr6_-_30210378 13.42 ENSDART00000157359
ENSDART00000113924
leucine rich repeat containing 7
chr18_-_12957451 13.40 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr2_+_34767171 13.37 ENSDART00000145451
astrotactin 1
chr1_-_31505144 13.35 ENSDART00000087115
regulating synaptic membrane exocytosis 1b
chr16_+_2840775 13.35 ENSDART00000108735
C-type lectin domain family 3, member Ba
chr25_+_21833287 13.35 ENSDART00000187606
creatine kinase, mitochondrial 1
chr11_+_24966182 13.33 ENSDART00000185088
sulfatase 2a
chr23_-_12015139 13.28 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
chr16_-_12953739 13.26 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr17_-_36936649 13.23 ENSDART00000145236
dihydropyrimidinase-like 5a
chr4_-_11163112 13.17 ENSDART00000188854
protein arginine methyltransferase 8b
chr14_-_2322484 13.13 ENSDART00000167806
si:ch73-379j16.2
chr5_+_65491390 13.10 ENSDART00000159921
si:dkey-21e5.1
chr2_+_19777146 13.09 ENSDART00000038648
polypyrimidine tract binding protein 2b
chr16_+_33593116 13.05 ENSDART00000013148
POU class 3 homeobox 1
chr4_-_64284924 12.97 ENSDART00000166733

chr25_-_7925269 12.94 ENSDART00000014274
glucuronic acid epimerase a
chr10_-_22249444 12.93 ENSDART00000148831
fibroblast growth factor 11b
chr20_-_26042070 12.92 ENSDART00000140255
si:dkey-12h9.6
chr2_+_20430366 12.91 ENSDART00000155108
si:ch211-153l6.6
chr8_-_52473054 12.87 ENSDART00000193658
phytanoyl-CoA 2-hydroxylase interacting protein
chr23_-_36449111 12.80 ENSDART00000110478
zgc:174906

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19a+sox2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
7.3 21.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.2 28.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
6.8 20.4 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
6.8 20.3 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
6.3 25.3 GO:0021557 oculomotor nerve development(GO:0021557)
5.7 23.0 GO:0016123 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
5.5 43.9 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
5.2 20.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
5.0 15.0 GO:0071361 cellular response to ethanol(GO:0071361)
4.7 18.9 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
4.1 20.3 GO:0070208 protein heterotrimerization(GO:0070208)
4.1 36.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
4.0 12.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
3.8 11.5 GO:0021960 anterior commissure morphogenesis(GO:0021960)
3.7 32.9 GO:0050714 positive regulation of protein secretion(GO:0050714)
3.5 13.9 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
3.4 13.7 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
3.4 10.2 GO:2000434 regulation of protein neddylation(GO:2000434)
3.4 10.2 GO:0021961 posterior commissure morphogenesis(GO:0021961)
3.2 73.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
3.2 47.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
3.1 12.6 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
2.9 8.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
2.9 8.7 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
2.9 11.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
2.9 22.9 GO:0021634 optic nerve formation(GO:0021634)
2.8 39.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
2.8 11.2 GO:0003322 pancreatic A cell development(GO:0003322)
2.8 19.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
2.8 33.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
2.7 18.9 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
2.7 8.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
2.6 36.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
2.6 23.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
2.5 15.3 GO:0022029 telencephalon cell migration(GO:0022029)
2.5 22.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
2.5 32.2 GO:0010996 response to auditory stimulus(GO:0010996)
2.5 39.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
2.4 7.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
2.4 23.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
2.4 7.1 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
2.3 25.5 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
2.3 9.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
2.3 16.1 GO:0019857 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
2.2 6.7 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
2.2 26.6 GO:0006285 base-excision repair, AP site formation(GO:0006285)
2.2 26.4 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
2.2 8.7 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
2.2 19.4 GO:0001840 neural plate development(GO:0001840)
2.1 10.7 GO:0023041 neuronal signal transduction(GO:0023041)
2.1 14.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
2.1 12.6 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
2.1 8.4 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
2.1 18.5 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
2.0 22.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
1.9 23.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
1.9 7.6 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
1.9 7.5 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
1.9 11.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.9 7.5 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
1.8 5.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.8 9.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.8 8.9 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
1.8 447.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.7 17.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
1.7 13.7 GO:0021588 cerebellum formation(GO:0021588)
1.7 22.2 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.7 8.4 GO:0090527 actin filament reorganization(GO:0090527)
1.7 5.0 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
1.7 5.0 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
1.7 31.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
1.7 8.3 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.6 14.8 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
1.6 6.6 GO:0035521 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.6 57.0 GO:0007019 microtubule depolymerization(GO:0007019)
1.6 61.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
1.6 16.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
1.6 8.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
1.6 68.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
1.6 22.0 GO:0007398 ectoderm development(GO:0007398)
1.6 3.1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
1.6 34.6 GO:0030032 lamellipodium assembly(GO:0030032)
1.5 4.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.5 9.2 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
1.5 27.7 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
1.5 4.5 GO:0046069 cGMP catabolic process(GO:0046069)
1.5 17.9 GO:0000729 DNA double-strand break processing(GO:0000729)
1.5 4.4 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
1.5 27.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.5 10.2 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
1.4 20.1 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.4 4.2 GO:0030043 actin filament fragmentation(GO:0030043)
1.4 9.8 GO:0010002 cardioblast differentiation(GO:0010002)
1.4 5.6 GO:0010226 response to lithium ion(GO:0010226)
1.4 8.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.3 8.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.3 5.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.3 17.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
1.3 11.7 GO:0001780 neutrophil homeostasis(GO:0001780) response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.3 6.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.3 42.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
1.3 46.9 GO:0006376 mRNA splice site selection(GO:0006376)
1.2 21.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
1.2 2.5 GO:0043901 negative regulation of multi-organism process(GO:0043901)
1.2 9.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
1.2 10.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.2 11.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.2 11.6 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
1.2 4.6 GO:0070987 error-free translesion synthesis(GO:0070987)
1.1 79.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
1.1 18.3 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
1.1 12.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
1.1 12.4 GO:0038203 TORC2 signaling(GO:0038203)
1.1 14.6 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.1 15.6 GO:0061300 cerebellum vasculature development(GO:0061300)
1.1 5.5 GO:0031627 telomeric loop formation(GO:0031627)
1.1 15.5 GO:0045773 positive regulation of axon extension(GO:0045773)
1.1 7.7 GO:0021982 pineal gland development(GO:0021982)
1.1 5.5 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
1.1 36.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.1 5.4 GO:0036371 protein localization to T-tubule(GO:0036371)
1.1 10.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.1 10.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
1.0 3.1 GO:0003403 optic vesicle formation(GO:0003403)
1.0 2.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
1.0 3.1 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
1.0 16.2 GO:0036065 fucosylation(GO:0036065)
1.0 26.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.0 14.0 GO:0032264 IMP salvage(GO:0032264)
1.0 8.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.0 4.9 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.9 6.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.9 29.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.9 8.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.9 6.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.9 3.6 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.9 4.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.9 1.8 GO:0007021 tubulin complex assembly(GO:0007021) post-chaperonin tubulin folding pathway(GO:0007023)
0.9 4.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.9 2.7 GO:0060845 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.9 4.4 GO:0061056 sclerotome development(GO:0061056)
0.9 13.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.9 4.3 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.9 5.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.8 4.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.8 2.5 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.8 5.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.8 21.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.8 10.8 GO:0072576 liver morphogenesis(GO:0072576)
0.8 20.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.8 11.5 GO:0001556 oocyte maturation(GO:0001556)
0.8 5.7 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.8 4.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.8 7.3 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.8 8.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.8 32.2 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.8 15.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.8 7.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.8 22.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.8 3.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.8 27.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.8 1.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.8 8.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.8 4.5 GO:1903826 arginine transport(GO:0015809) L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.8 2.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.8 9.8 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.7 7.4 GO:0014812 muscle cell migration(GO:0014812)
0.7 7.2 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.7 5.7 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.7 12.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.7 1.4 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.7 42.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.7 5.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.7 9.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.7 2.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.7 4.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.7 5.4 GO:0044211 CTP salvage(GO:0044211)
0.7 5.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.7 4.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 12.0 GO:0070828 heterochromatin organization(GO:0070828)
0.7 35.5 GO:0030282 bone mineralization(GO:0030282)
0.6 5.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.6 5.1 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.6 2.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.6 19.9 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.6 8.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 27.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.6 9.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.6 3.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.6 7.4 GO:0030878 thyroid gland development(GO:0030878)
0.6 13.5 GO:0006491 N-glycan processing(GO:0006491)
0.6 6.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.6 1.2 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.6 3.6 GO:0035313 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.6 7.7 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.6 5.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.6 2.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.6 5.7 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.6 2.9 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.6 8.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.6 1.7 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.6 6.7 GO:0060384 innervation(GO:0060384) axonogenesis involved in innervation(GO:0060385)
0.6 11.7 GO:0015671 oxygen transport(GO:0015671)
0.6 11.1 GO:0018149 peptide cross-linking(GO:0018149)
0.6 5.0 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.6 2.8 GO:0000012 single strand break repair(GO:0000012)
0.5 3.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.5 8.7 GO:0016926 protein desumoylation(GO:0016926)
0.5 3.8 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.5 1.6 GO:0071922 regulation of sister chromatid cohesion(GO:0007063) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.5 3.8 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.5 11.8 GO:0060541 respiratory system development(GO:0060541)
0.5 2.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.5 5.8 GO:0072176 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.5 2.6 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.5 6.3 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.5 14.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.5 8.8 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.5 1.5 GO:0042762 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of sulfur metabolic process(GO:0042762) regulation of homocysteine metabolic process(GO:0050666)
0.5 14.2 GO:0070831 basement membrane assembly(GO:0070831)
0.5 6.1 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.5 6.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.5 1.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.5 2.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.5 9.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.5 44.6 GO:0010970 establishment of localization by movement along microtubule(GO:0010970)
0.5 11.4 GO:0050795 regulation of behavior(GO:0050795)
0.5 10.3 GO:0021854 hypothalamus development(GO:0021854)
0.5 37.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.5 5.3 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.5 48.9 GO:0008360 regulation of cell shape(GO:0008360)
0.5 4.8 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.5 3.8 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.5 2.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 9.5 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 3.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.5 2.3 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.5 89.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.5 4.6 GO:0035907 dorsal aorta development(GO:0035907)
0.5 1.4 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.5 2.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.5 1.4 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.5 4.1 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.4 2.7 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.4 13.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.4 54.7 GO:0051260 protein homooligomerization(GO:0051260)
0.4 15.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.4 1.7 GO:0080009 mRNA methylation(GO:0080009)
0.4 2.6 GO:0003160 endocardium morphogenesis(GO:0003160)
0.4 2.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 2.5 GO:0050936 xanthophore differentiation(GO:0050936)
0.4 1.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.4 10.9 GO:0071696 ectodermal placode development(GO:0071696)
0.4 17.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 5.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.4 4.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.4 6.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.4 1.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.4 1.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.4 3.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 27.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.4 4.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.4 1.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.4 2.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.4 43.2 GO:0050684 regulation of mRNA processing(GO:0050684)
0.4 8.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.4 2.2 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.4 7.7 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.4 1.1 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 14.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.4 15.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.4 1.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.3 3.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 3.7 GO:0019226 transmission of nerve impulse(GO:0019226)
0.3 1.4 GO:0048532 anatomical structure arrangement(GO:0048532)
0.3 11.9 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.3 3.0 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.3 1.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.3 18.7 GO:0007338 single fertilization(GO:0007338)
0.3 26.4 GO:0006475 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393)
0.3 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 6.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 3.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 6.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 57.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.3 1.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 17.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 7.4 GO:0010770 positive regulation of cell morphogenesis involved in differentiation(GO:0010770)
0.3 7.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 11.9 GO:0030336 negative regulation of cell migration(GO:0030336)
0.3 2.4 GO:0060021 palate development(GO:0060021)
0.3 1.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 11.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.3 6.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.3 8.3 GO:0032456 endocytic recycling(GO:0032456)
0.3 1.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026) peptidyl-lysine dimethylation(GO:0018027)
0.3 64.1 GO:0008380 RNA splicing(GO:0008380)
0.3 12.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.3 4.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.3 27.5 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.3 2.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 11.6 GO:0048484 enteric nervous system development(GO:0048484)
0.3 6.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 2.2 GO:0000423 macromitophagy(GO:0000423)
0.3 4.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.3 4.9 GO:0003171 atrioventricular valve development(GO:0003171)
0.3 4.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.3 0.5 GO:0046324 regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324)
0.3 1.0 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.3 6.2 GO:1902275 regulation of chromatin organization(GO:1902275)
0.3 5.6 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.3 3.0 GO:0042572 retinol metabolic process(GO:0042572)
0.2 3.2 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.2 0.5 GO:2000142 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.2 4.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 3.1 GO:0031103 axon regeneration(GO:0031103)
0.2 5.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 3.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 2.8 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.2 5.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 3.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 0.7 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.2 124.6 GO:0007017 microtubule-based process(GO:0007017)
0.2 3.9 GO:0007634 optokinetic behavior(GO:0007634)
0.2 1.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 7.4 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.2 5.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.2 13.0 GO:0010107 potassium ion import(GO:0010107)
0.2 4.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 9.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 2.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 3.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 2.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 7.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.2 5.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 2.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 3.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 22.4 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.2 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 4.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 3.0 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.2 5.3 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.2 68.9 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.2 3.9 GO:0048634 regulation of muscle organ development(GO:0048634)
0.2 2.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 9.8 GO:0007602 phototransduction(GO:0007602)
0.2 1.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 1.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 1.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 12.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.2 11.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 1.4 GO:0010458 exit from mitosis(GO:0010458)
0.2 2.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.3 GO:0032196 transposition(GO:0032196)
0.2 2.0 GO:0048854 brain morphogenesis(GO:0048854)
0.2 10.7 GO:0002040 sprouting angiogenesis(GO:0002040)
0.2 4.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 15.4 GO:0016579 protein deubiquitination(GO:0016579)
0.2 1.1 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.6 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 2.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 16.3 GO:1901342 regulation of vasculature development(GO:1901342)
0.1 0.4 GO:1901255 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 7.2 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 4.0 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 5.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 7.5 GO:0006813 potassium ion transport(GO:0006813)
0.1 0.6 GO:0014004 microglia differentiation(GO:0014004)
0.1 2.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 11.3 GO:0030334 regulation of cell migration(GO:0030334)
0.1 1.1 GO:0006188 IMP biosynthetic process(GO:0006188)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 4.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 3.1 GO:0001707 mesoderm formation(GO:0001707)
0.1 24.8 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 6.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.4 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.1 0.8 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.1 3.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.9 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 1.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 0.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 3.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 2.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 1.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 1.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.6 GO:0046512 sphingosine metabolic process(GO:0006670) diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.2 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 3.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.4 GO:1901655 cellular response to ketone(GO:1901655)
0.0 9.4 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)
0.0 3.6 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0060996 dendritic spine development(GO:0060996) dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 3.9 GO:0031175 neuron projection development(GO:0031175)
0.0 0.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.3 53.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
4.4 26.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
4.4 13.2 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
4.1 73.4 GO:0043209 myelin sheath(GO:0043209)
3.6 151.2 GO:0043204 perikaryon(GO:0043204)
3.5 48.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
3.4 17.0 GO:0005883 neurofilament(GO:0005883)
3.4 3.4 GO:0071564 npBAF complex(GO:0071564)
3.3 20.0 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
3.2 22.1 GO:0035517 PR-DUB complex(GO:0035517)
3.0 33.2 GO:0044295 axonal growth cone(GO:0044295)
2.8 8.5 GO:0031213 RSF complex(GO:0031213)
2.6 7.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.5 12.5 GO:0008091 spectrin(GO:0008091)
2.3 23.3 GO:0036449 microtubule minus-end(GO:0036449)
2.3 25.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.8 42.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.8 70.8 GO:0043679 axon terminus(GO:0043679)
1.7 17.3 GO:0098982 GABA-ergic synapse(GO:0098982)
1.7 5.0 GO:0042382 paraspeckles(GO:0042382)
1.7 40.0 GO:0035102 PRC1 complex(GO:0035102)
1.6 4.7 GO:1990745 EARP complex(GO:1990745)
1.5 4.5 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
1.5 17.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.5 27.7 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
1.4 5.6 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.4 46.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.2 8.7 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
1.2 22.1 GO:0030992 intraciliary transport particle B(GO:0030992)
1.2 18.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.2 32.5 GO:0000145 exocyst(GO:0000145)
1.1 8.0 GO:0033010 paranodal junction(GO:0033010)
1.1 4.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.1 16.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.1 4.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.1 9.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.1 4.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
1.0 11.3 GO:0035101 FACT complex(GO:0035101)
1.0 18.4 GO:0005801 cis-Golgi network(GO:0005801)
1.0 23.4 GO:0060170 ciliary membrane(GO:0060170)
1.0 4.0 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
1.0 3.9 GO:0008537 proteasome activator complex(GO:0008537)
1.0 15.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.9 32.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9 3.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.9 2.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.9 5.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.8 4.2 GO:0000938 GARP complex(GO:0000938)
0.8 43.7 GO:0030175 filopodium(GO:0030175)
0.8 3.3 GO:0044609 DBIRD complex(GO:0044609)
0.8 19.8 GO:0071565 nBAF complex(GO:0071565)
0.8 2.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.8 5.4 GO:0030315 T-tubule(GO:0030315)
0.7 41.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.7 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.7 5.8 GO:0072487 MSL complex(GO:0072487)
0.7 27.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.7 8.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.7 18.0 GO:0005921 gap junction(GO:0005921)
0.7 7.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.7 68.0 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.7 6.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.7 6.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 48.7 GO:0043025 neuronal cell body(GO:0043025)
0.6 13.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.6 8.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 110.3 GO:0030424 axon(GO:0030424)
0.6 7.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.6 16.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.6 24.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.6 2.9 GO:0030893 meiotic cohesin complex(GO:0030893)
0.6 8.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.6 2.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.6 5.7 GO:0045171 intercellular bridge(GO:0045171)
0.6 10.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.6 2.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 11.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.5 3.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 32.3 GO:0031225 anchored component of membrane(GO:0031225)
0.5 51.5 GO:0005795 Golgi stack(GO:0005795)
0.5 15.7 GO:0035861 site of double-strand break(GO:0035861)
0.5 7.8 GO:0032993 protein-DNA complex(GO:0032993)
0.5 13.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.5 7.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.5 206.2 GO:0043005 neuron projection(GO:0043005)
0.5 8.4 GO:0090544 BAF-type complex(GO:0090544)
0.5 3.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.5 3.9 GO:0032783 ELL-EAF complex(GO:0032783)
0.5 6.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.5 5.2 GO:0034451 centriolar satellite(GO:0034451)
0.5 8.8 GO:0097546 ciliary base(GO:0097546)
0.5 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.4 2.2 GO:0030897 HOPS complex(GO:0030897)
0.4 38.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 19.0 GO:0005911 cell-cell junction(GO:0005911)
0.4 1.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 1.7 GO:0005685 U1 snRNP(GO:0005685)
0.4 15.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.4 8.2 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.4 4.9 GO:0036038 MKS complex(GO:0036038)
0.4 2.8 GO:0016586 RSC complex(GO:0016586)
0.4 12.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.4 24.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 5.1 GO:1990246 uniplex complex(GO:1990246)
0.4 8.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 3.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.4 2.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 28.4 GO:0030141 secretory granule(GO:0030141)
0.4 2.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.4 6.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 1.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 2.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.4 1.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 22.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.3 8.9 GO:0030496 midbody(GO:0030496)
0.3 10.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 2.7 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.3 5.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 1.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 3.4 GO:0005686 U2 snRNP(GO:0005686)
0.3 4.8 GO:0055037 recycling endosome(GO:0055037)
0.3 8.5 GO:0031201 SNARE complex(GO:0031201)
0.3 9.0 GO:0032587 ruffle membrane(GO:0032587)
0.3 6.5 GO:0031932 TORC2 complex(GO:0031932)
0.3 25.7 GO:0005925 focal adhesion(GO:0005925)
0.3 335.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 9.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.3 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.3 2.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 82.8 GO:0000139 Golgi membrane(GO:0000139)
0.2 13.5 GO:0009986 cell surface(GO:0009986)
0.2 13.0 GO:0016592 mediator complex(GO:0016592)
0.2 5.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.5 GO:0008180 COP9 signalosome(GO:0008180)
0.2 26.7 GO:0045202 synapse(GO:0045202)
0.2 8.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 14.2 GO:0031252 cell leading edge(GO:0031252)
0.2 52.6 GO:0005874 microtubule(GO:0005874)
0.2 3.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.0 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.2 13.2 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.2 0.6 GO:0010369 chromocenter(GO:0010369)
0.2 1.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 8.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.2 42.0 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.2 2.3 GO:0098858 actin-based cell projection(GO:0098858)
0.2 8.8 GO:0031902 late endosome membrane(GO:0031902)
0.2 0.5 GO:0097361 CIA complex(GO:0097361)
0.2 2.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 7.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 1.1 GO:0089701 U2AF(GO:0089701)
0.1 2.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.1 18.4 GO:0005813 centrosome(GO:0005813)
0.1 8.6 GO:0016607 nuclear speck(GO:0016607)
0.1 3.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 13.7 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 8.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.1 27.6 GO:0005794 Golgi apparatus(GO:0005794)
0.1 2.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.5 GO:0070938 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1 6.9 GO:0005681 spliceosomal complex(GO:0005681)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 397.3 GO:0005634 nucleus(GO:0005634)
0.0 6.3 GO:0005768 endosome(GO:0005768)
0.0 2.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 85.8 GO:0005886 plasma membrane(GO:0005886)
0.0 1.9 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.3 53.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
7.5 22.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
6.4 25.7 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
5.9 23.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
5.7 23.0 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
5.6 22.3 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
3.9 11.7 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
3.9 58.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.8 15.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.8 15.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
3.4 20.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
3.3 39.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
3.1 31.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
3.1 15.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
3.1 9.2 GO:0038046 enkephalin receptor activity(GO:0038046)
3.1 12.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
3.0 21.1 GO:0098809 nitrite reductase activity(GO:0098809)
3.0 42.0 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
3.0 27.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
3.0 26.6 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
2.8 19.6 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
2.7 13.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
2.5 14.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.5 17.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.4 31.5 GO:0030507 spectrin binding(GO:0030507)
2.4 7.2 GO:0005252 open rectifier potassium channel activity(GO:0005252)
2.3 25.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.3 16.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
2.2 29.1 GO:0045503 dynein light chain binding(GO:0045503)
2.2 11.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
2.2 17.5 GO:0004977 melanocortin receptor activity(GO:0004977)
2.1 19.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.1 12.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.0 4.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
2.0 22.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
2.0 18.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9 13.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.9 89.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.8 5.5 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
1.7 10.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.7 22.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.7 22.1 GO:0031628 opioid receptor binding(GO:0031628)
1.7 11.8 GO:0030274 LIM domain binding(GO:0030274)
1.7 15.0 GO:0016934 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.6 31.1 GO:0008301 DNA binding, bending(GO:0008301)
1.6 37.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
1.6 28.3 GO:0033691 sialic acid binding(GO:0033691)
1.5 9.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.5 7.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.4 54.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.3 8.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.3 28.0 GO:0046875 ephrin receptor binding(GO:0046875)
1.3 10.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.3 5.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
1.3 14.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3 30.1 GO:0001540 beta-amyloid binding(GO:0001540)
1.2 7.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.2 33.3 GO:0017080 sodium channel regulator activity(GO:0017080)
1.2 17.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.2 5.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.2 20.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.1 37.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.1 4.6 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
1.1 4.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.1 9.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.1 6.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.1 5.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
1.1 6.4 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
1.1 9.5 GO:0048039 ubiquinone binding(GO:0048039)
1.0 13.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.0 3.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
1.0 20.8 GO:0003785 actin monomer binding(GO:0003785)
1.0 3.1 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
1.0 7.2 GO:0001032 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
1.0 3.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
1.0 5.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
1.0 8.9 GO:0043515 kinetochore binding(GO:0043515)
1.0 6.0 GO:0016361 activin receptor activity, type I(GO:0016361)
1.0 7.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.0 44.8 GO:0008013 beta-catenin binding(GO:0008013)
1.0 17.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
1.0 16.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.9 4.7 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.9 8.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.9 3.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.9 3.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.9 4.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.9 10.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.9 9.2 GO:0005522 profilin binding(GO:0005522)
0.9 4.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.9 5.4 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.9 5.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.9 4.4 GO:0008432 JUN kinase binding(GO:0008432)
0.9 14.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.9 19.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.9 2.6 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.9 42.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.9 11.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 2.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.9 6.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.8 6.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 21.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.8 4.7 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.8 25.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.8 12.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.8 10.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.8 6.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.7 4.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.7 12.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 3.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 5.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.7 4.9 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.7 3.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 5.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.7 9.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.7 24.6 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.7 11.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.7 5.4 GO:0004849 uridine kinase activity(GO:0004849)
0.7 2.0 GO:0030623 U5 snRNA binding(GO:0030623)
0.7 10.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.7 2.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7 6.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.7 3.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 15.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.6 4.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.6 14.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.6 243.8 GO:0015631 tubulin binding(GO:0015631)
0.6 9.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 7.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.6 3.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.6 8.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 8.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 7.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.6 4.8 GO:0015232 heme transporter activity(GO:0015232)
0.6 4.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6 8.9 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.6 8.8 GO:0019894 kinesin binding(GO:0019894)
0.6 27.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 10.5 GO:0005080 protein kinase C binding(GO:0005080)
0.6 2.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.6 3.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.6 22.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.6 6.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.6 11.4 GO:0097602 cullin family protein binding(GO:0097602)
0.6 7.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.6 5.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.6 3.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.6 11.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 5.0 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.5 8.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.5 2.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5 45.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.5 60.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.5 3.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 3.5 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.5 2.5 GO:0050699 WW domain binding(GO:0050699)
0.5 19.3 GO:0044325 ion channel binding(GO:0044325)
0.5 3.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.5 3.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 18.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.5 14.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 20.2 GO:0019905 syntaxin binding(GO:0019905)
0.5 6.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.5 14.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 1.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 1.4 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.4 7.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.4 8.9 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.4 1.8 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.4 3.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 6.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.4 420.5 GO:0005509 calcium ion binding(GO:0005509)
0.4 16.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 3.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 1.2 GO:0035197 siRNA binding(GO:0035197)
0.4 3.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 16.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 4.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.4 2.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.4 6.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 17.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.4 134.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.4 8.3 GO:0042056 chemoattractant activity(GO:0042056)
0.4 9.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.4 9.4 GO:0022829 wide pore channel activity(GO:0022829)
0.4 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.4 1.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 2.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.3 4.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 1.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.3 8.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 17.1 GO:0031491 nucleosome binding(GO:0031491)
0.3 2.7 GO:0001972 retinoic acid binding(GO:0001972)
0.3 5.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3 6.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.3 1.6 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.3 2.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.3 6.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 27.2 GO:0005516 calmodulin binding(GO:0005516)
0.3 4.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 1.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.3 7.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 7.0 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.3 6.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 11.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 0.8 GO:0032183 SUMO binding(GO:0032183) SUMO polymer binding(GO:0032184)
0.3 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 1.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 1.1 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.3 23.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 107.2 GO:0003924 GTPase activity(GO:0003924)
0.3 6.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.3 42.9 GO:0042393 histone binding(GO:0042393)
0.3 93.4 GO:0005096 GTPase activator activity(GO:0005096)
0.3 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 30.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.3 4.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.3 3.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 5.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 7.6 GO:0045502 dynein binding(GO:0045502)
0.2 8.6 GO:0003684 damaged DNA binding(GO:0003684)
0.2 11.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.2 2.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 2.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 2.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 5.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 3.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.5 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 48.6 GO:0030246 carbohydrate binding(GO:0030246)
0.2 4.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 9.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 0.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 1.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 4.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 4.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2 7.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 29.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 0.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 25.1 GO:0003682 chromatin binding(GO:0003682)
0.2 5.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 3.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 3.0 GO:0030552 cAMP binding(GO:0030552)
0.2 5.6 GO:0051087 chaperone binding(GO:0051087)
0.2 1.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 4.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 7.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.5 GO:0017069 snRNA binding(GO:0017069)
0.1 9.7 GO:0008201 heparin binding(GO:0008201)
0.1 1.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 2.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 253.0 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 5.5 GO:0004527 exonuclease activity(GO:0004527)
0.1 16.3 GO:0005179 hormone activity(GO:0005179)
0.1 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 5.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 6.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 4.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.5 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 1.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 4.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 7.4 GO:0042802 identical protein binding(GO:0042802)
0.1 0.5 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 15.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 13.9 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.9 40.1 PID REELIN PATHWAY Reelin signaling pathway
1.3 11.4 PID S1P S1P4 PATHWAY S1P4 pathway
1.2 8.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
1.1 36.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.1 42.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.1 17.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.9 27.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.9 7.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 2.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.6 16.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.5 4.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 6.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 24.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 7.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 2.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 7.4 PID IL27 PATHWAY IL27-mediated signaling events
0.4 15.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 3.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.4 11.5 PID INSULIN PATHWAY Insulin Pathway
0.3 5.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 7.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 1.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 6.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 9.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 4.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 2.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 3.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 2.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 3.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 3.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 6.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 3.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 4.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
3.7 11.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
2.3 9.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
2.1 32.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.6 6.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.5 7.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
1.4 31.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.3 20.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.2 26.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.2 21.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.1 11.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.1 8.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.1 8.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 24.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.9 15.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.8 13.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.8 13.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 12.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.8 8.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 3.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.8 4.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7 5.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 5.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.7 6.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.7 6.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.6 6.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.6 14.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.6 7.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.6 7.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 2.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 9.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 4.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 8.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4 3.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 4.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.4 5.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.4 5.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 22.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.3 3.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 9.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.3 10.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 4.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 2.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 3.4 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.3 1.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.3 4.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3 3.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 1.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 5.4 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.2 2.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 7.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 3.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 4.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 11.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.1 2.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 14.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.2 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 3.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation