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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rxrbb

Z-value: 0.72

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Transcription factors associated with rxrbb

Gene Symbol Gene ID Gene Info
rxrbb
ENSDARG00000002006 retinoid x receptor, beta b
rxrbb
ENSDARG00000117079 retinoid x receptor, beta b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rxrbbdr11_v1_chr16_+_18535618_185356180.637.4e-12Click!

Activity profile of rxrbb motif

Sorted Z-values of rxrbb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_25848231 8.13 ENSDART00000027973
fabp2
fatty acid binding protein 2, intestinal
chr13_-_9318891 7.98 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr23_-_45504991 7.95 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr3_+_30257582 6.64 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
mybpc2a
myosin binding protein C, fast type a
chr25_+_21829777 6.57 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr18_-_48517040 6.42 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr7_-_38633867 6.09 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr10_+_45128375 5.95 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr10_-_17745345 5.34 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr18_-_48492951 5.28 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr18_-_48508585 5.19 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr10_+_20128267 4.61 ENSDART00000064615
dmtn
dematin actin binding protein
chr8_+_36803415 4.56 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr13_+_28819768 3.92 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr2_+_42191592 3.88 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr25_+_31238606 3.77 ENSDART00000149439
tnni2a.2
troponin I type 2a (skeletal, fast), tandem duplicate 2
chr21_-_26495700 3.68 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr24_-_21172122 3.66 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr5_-_23362602 3.42 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr13_+_28821841 3.21 ENSDART00000179900
CU639469.1

chr25_-_19420949 3.15 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr6_-_11523987 3.11 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr20_-_53078607 2.97 ENSDART00000163494
ENSDART00000191730
CABZ01066813.1

chr23_+_30730121 2.97 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr11_-_11910225 2.75 ENSDART00000159922
si:ch211-69b7.6
si:ch211-69b7.6
chr1_+_23783349 2.63 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr23_-_42810664 2.59 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr19_+_3056450 2.58 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr5_+_38276582 2.57 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr18_+_27515640 2.54 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr22_-_3595439 2.53 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr1_+_58353661 2.52 ENSDART00000140074
si:dkey-222h21.2
si:dkey-222h21.2
chr18_-_48550426 2.49 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr9_+_54644626 2.45 ENSDART00000190609
egfl6
EGF-like-domain, multiple 6
chr19_+_2275019 2.42 ENSDART00000136138
itgb8
integrin, beta 8
chr6_+_40775800 2.41 ENSDART00000085090
si:ch211-157b11.8
si:ch211-157b11.8
chr19_+_2631565 2.40 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr2_-_22659450 2.38 ENSDART00000115025
thap4
THAP domain containing 4
chr5_-_27994679 2.33 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr17_+_11675362 2.30 ENSDART00000157911
kif26ba
kinesin family member 26Ba
chr18_+_31410652 2.27 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr24_-_1021318 2.25 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr8_+_1009831 2.19 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr19_+_177455 2.15 ENSDART00000111580
tmem65
transmembrane protein 65
chr8_-_979735 2.11 ENSDART00000149612
znf366
zinc finger protein 366
chr15_+_47618221 2.06 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr15_+_47386939 2.06 ENSDART00000128224
FO904873.1

chr6_+_60036767 2.04 ENSDART00000155009
tgm8
transglutaminase 8
chr1_+_58182400 2.01 ENSDART00000144784
si:ch211-15j1.1
si:ch211-15j1.1
chr1_+_58119117 2.01 ENSDART00000146788
si:ch211-15j1.5
si:ch211-15j1.5
chr5_-_33255759 2.00 ENSDART00000085531
prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr25_+_20119466 1.89 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr2_-_32555625 1.87 ENSDART00000056641
ENSDART00000137531
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr25_-_31118923 1.86 ENSDART00000009126
ENSDART00000188286
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr24_-_29586082 1.85 ENSDART00000136763
vav3a
vav 3 guanine nucleotide exchange factor a
chr15_+_15856178 1.76 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr13_-_4018888 1.72 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr16_+_14033121 1.69 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr1_+_58303892 1.69 ENSDART00000147678
CR769768.1

chr23_+_41679586 1.67 ENSDART00000067662
CU914487.1

chr22_-_28668442 1.67 ENSDART00000182377
col8a1b
collagen, type VIII, alpha 1b
chr2_-_8102169 1.66 ENSDART00000131955
pls1
plastin 1 (I isoform)
chr9_-_37613792 1.65 ENSDART00000138345
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr9_+_34380299 1.59 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr12_-_31012741 1.54 ENSDART00000145967
tcf7l2
transcription factor 7 like 2
chr9_+_22782027 1.53 ENSDART00000090816
rif1
replication timing regulatory factor 1
chr1_+_58442694 1.53 ENSDART00000160897
zgc:194906
zgc:194906
chr1_+_58150000 1.51 ENSDART00000137836
si:ch211-15j1.3
si:ch211-15j1.3
chr17_-_7371564 1.48 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr23_-_18595020 1.46 ENSDART00000187032
ENSDART00000191047
ikbkg
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr1_+_58139102 1.44 ENSDART00000134826
si:ch211-15j1.4
si:ch211-15j1.4
chr6_+_39930825 1.44 ENSDART00000182352
ENSDART00000186643
ENSDART00000190513
ENSDART00000065092
ENSDART00000188645
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr20_-_51656512 1.44 ENSDART00000129965
LO018154.1

chr17_+_45737992 1.44 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
aspg
asparaginase homolog (S. cerevisiae)
chr4_+_68519945 1.39 ENSDART00000171148
si:dkey-16p6.1
si:dkey-16p6.1
chr16_+_25809235 1.38 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr21_+_1119046 1.35 ENSDART00000184678
CABZ01088049.1

chr1_+_58260886 1.30 ENSDART00000110453
si:dkey-222h21.8
si:dkey-222h21.8
chr24_-_1341543 1.27 ENSDART00000169341
nrp1a
neuropilin 1a
chr19_-_3056235 1.27 ENSDART00000137020
bop1
block of proliferation 1
chr12_+_46708920 1.26 ENSDART00000153089
exoc7
exocyst complex component 7
chr4_-_38421217 1.26 ENSDART00000164517
znf1092
szinc finger protein 1092
chr17_-_20711735 1.20 ENSDART00000150056
ank3b
ankyrin 3b
chr23_-_27050083 1.19 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr18_+_30441740 1.17 ENSDART00000189074
gse1
Gse1 coiled-coil protein
chr1_-_58868306 1.16 ENSDART00000166615
dnm2b
dynamin 2b
chr19_-_9867001 1.14 ENSDART00000091695
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr3_+_12755535 1.13 ENSDART00000161286
cyp2k17
cytochrome P450, family 2, subfamily K, polypeptide17
chr4_-_16451375 1.12 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr16_-_29146624 1.07 ENSDART00000159814
ENSDART00000009826
mef2d
myocyte enhancer factor 2d
chr9_+_32978302 1.07 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr21_-_35832548 1.01 ENSDART00000180840
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr10_+_589501 1.00 ENSDART00000188415
LO018557.1

chr20_-_18382708 1.00 ENSDART00000170864
ENSDART00000166762
ENSDART00000191333
vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr1_+_58312187 0.99 ENSDART00000142285
si:dkey-222h21.10
si:dkey-222h21.10
chr19_+_11214007 0.95 ENSDART00000127362
si:ch73-109i22.2
si:ch73-109i22.2
chr17_+_21817382 0.94 ENSDART00000079011
ENSDART00000189387
ikzf5
IKAROS family zinc finger 5
chr4_-_858434 0.94 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr4_-_37587110 0.93 ENSDART00000169302
znf1100
zinc finger protein 1100
chr16_-_24612871 0.92 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr15_+_22448456 0.91 ENSDART00000040542
ENSDART00000190270
ENSDART00000185897
arhgef12a
Rho guanine nucleotide exchange factor (GEF) 12a
chr2_+_36112273 0.91 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr19_+_5146460 0.90 ENSDART00000150740
si:dkey-89b17.4
si:dkey-89b17.4
chr21_-_43992027 0.90 ENSDART00000188612
cdx1b
caudal type homeobox 1 b
chr16_-_47483142 0.90 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr17_-_27200634 0.88 ENSDART00000185332
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr13_+_45980163 0.88 ENSDART00000074547
ENSDART00000005195
bsdc1
BSD domain containing 1
chr14_-_13048355 0.85 ENSDART00000166434
si:dkey-35h6.1
si:dkey-35h6.1
chr19_+_20713424 0.84 ENSDART00000129730
rab5aa
RAB5A, member RAS oncogene family, a
chr23_+_2914577 0.82 ENSDART00000184897
DHX35
zgc:158828
chr4_+_2655358 0.80 ENSDART00000007638
bcap29
B cell receptor associated protein 29
chr12_+_3848109 0.78 ENSDART00000144067
ENSDART00000192042
cabp5a
calcium binding protein 5a
chr2_-_22660232 0.76 ENSDART00000174742
thap4
THAP domain containing 4
chr4_+_45274792 0.76 ENSDART00000150295
znf1138
zinc finger protein 1138
chr7_-_8014186 0.74 ENSDART00000190012
si:cabz01030277.1
si:cabz01030277.1
chr7_-_8156169 0.73 ENSDART00000182960
ENSDART00000190184
ENSDART00000190885
ENSDART00000189867
ENSDART00000160836
si:cabz01030277.1
si:ch211-163c2.3
si:cabz01030277.1
si:ch211-163c2.3
chr17_+_21817859 0.73 ENSDART00000143832
ENSDART00000141462
ikzf5
IKAROS family zinc finger 5
chr20_-_26937453 0.67 ENSDART00000139756
ftr97
finTRIM family, member 97
chr1_+_58312680 0.66 ENSDART00000138007
si:dkey-222h21.10
si:dkey-222h21.10
chr24_+_39034090 0.64 ENSDART00000185763
capn15
calpain 15
chr18_+_27926839 0.60 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr2_-_7696503 0.59 ENSDART00000169709
CABZ01055306.1

chr21_-_40015530 0.55 ENSDART00000084237
slc47a2.1
solute carrier family 47 (multidrug and toxin extrusion), member 2.1
chr14_+_30413312 0.55 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr19_+_19032141 0.54 ENSDART00000192432
cpne4b
copine IVb
chr13_-_41546779 0.53 ENSDART00000163331
pcdh15a
protocadherin-related 15a
chr1_+_57050899 0.52 ENSDART00000152601
si:ch211-1f22.14
si:ch211-1f22.14
chr15_+_45640906 0.46 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr5_-_20491198 0.46 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr13_+_21826369 0.43 ENSDART00000165150
ENSDART00000192115
zswim8
zinc finger, SWIM-type containing 8
chr5_-_32890807 0.43 ENSDART00000007512
pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr9_-_25255490 0.41 ENSDART00000141502
htr2aa
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr25_+_15933411 0.39 ENSDART00000191581
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr24_+_81527 0.38 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr17_-_25395395 0.37 ENSDART00000170233
fam167b
family with sequence similarity 167, member B
chr18_-_158541 0.36 ENSDART00000188914
ENSDART00000191052
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr2_+_57801960 0.35 ENSDART00000147966
si:dkeyp-68b7.10
si:dkeyp-68b7.10
chr10_-_29892486 0.32 ENSDART00000099983
bsx
brain-specific homeobox
chr21_-_44512893 0.32 ENSDART00000166853
zgc:136410
zgc:136410
chr20_-_26936887 0.31 ENSDART00000160827
ftr79
finTRIM family, member 79
chr13_-_36418921 0.31 ENSDART00000135804
dcaf5
ddb1 and cul4 associated factor 5
chr12_+_17439580 0.27 ENSDART00000189257
atad1b
ATPase family, AAA domain containing 1b
chr7_+_25000060 0.24 ENSDART00000039265
ENSDART00000141814
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr12_-_33568174 0.18 ENSDART00000142329
tdrkh
tudor and KH domain containing
chr4_-_75172216 0.17 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr12_+_19958845 0.17 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr3_+_39566999 0.15 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr21_-_11820379 0.15 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr8_+_999421 0.14 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr7_+_7495034 0.05 ENSDART00000102629
ENSDART00000180475
nit1
nitrilase 1
chr8_+_8012570 0.05 ENSDART00000183429
si:ch211-169p10.1
si:ch211-169p10.1
chr20_+_27519429 0.04 ENSDART00000136251
kif26aa
kinesin family member 26Aa
chr6_+_40952031 0.03 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr11_-_42230491 0.02 ENSDART00000164423
CABZ01030862.1

chr6_-_14004772 0.01 ENSDART00000185629
zgc:92027
zgc:92027

Network of associatons between targets according to the STRING database.

First level regulatory network of rxrbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.9 2.6 GO:0007414 axonal defasciculation(GO:0007414)
0.7 2.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.5 6.6 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.5 GO:0010226 response to lithium ion(GO:0010226)
0.3 1.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 0.8 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.3 1.3 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 19.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.9 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 4.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 2.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.2 0.8 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 1.6 GO:0050975 sensory perception of touch(GO:0050975)
0.2 2.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 5.9 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.4 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 3.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 4.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 2.6 GO:0009408 response to heat(GO:0009408)
0.1 1.0 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 2.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 2.0 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 3.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.5 GO:0032438 melanosome organization(GO:0032438)
0.1 2.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.1 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.3 GO:0021982 pineal gland development(GO:0021982)
0.1 1.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.2 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 3.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 3.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 2.0 GO:0006096 glycolytic process(GO:0006096)
0.0 2.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 1.5 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 4.1 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 1.7 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 2.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0005592 collagen type XI trimer(GO:0005592)
0.5 2.7 GO:0043034 costamere(GO:0043034)
0.5 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 3.0 GO:0035517 PR-DUB complex(GO:0035517)
0.4 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.4 2.3 GO:0005955 calcineurin complex(GO:0005955)
0.4 1.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 3.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.8 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 4.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 3.8 GO:0005861 troponin complex(GO:0005861)
0.1 7.1 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.4 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 5.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 19.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.2 3.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 10.5 GO:0005504 fatty acid binding(GO:0005504)
0.6 3.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 6.6 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 2.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 2.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 1.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 3.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 3.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.4 GO:0004067 asparaginase activity(GO:0004067)
0.2 2.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 2.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 5.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 4.1 GO:0019003 GDP binding(GO:0019003)
0.1 1.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.1 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.8 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 4.9 GO:0005178 integrin binding(GO:0005178)
0.1 9.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0016247 channel regulator activity(GO:0016247)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 7.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 6.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.0 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 1.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 2.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 7.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 2.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis