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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rargb_pparab

Z-value: 1.94

Motif logo

Transcription factors associated with rargb_pparab

Gene Symbol Gene ID Gene Info
ENSDARG00000054003 retinoic acid receptor, gamma b
ENSDARG00000054323 peroxisome proliferator-activated receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pparabdr11_v1_chr25_+_2198781_2198781-0.285.5e-03Click!
rargbdr11_v1_chr11_+_2089461_2089461-0.028.2e-01Click!

Activity profile of rargb_pparab motif

Sorted Z-values of rargb_pparab motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_24289641 35.32 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr3_+_39568290 33.75 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr11_+_11201096 31.14 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr13_+_22480496 25.09 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr3_+_39566999 23.34 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr6_-_40722200 21.29 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr17_-_5583345 19.99 ENSDART00000035944
chloride intracellular channel 5a
chr3_+_33300522 19.55 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr7_+_31871830 19.33 ENSDART00000139899
myosin binding protein C, cardiac
chr24_+_25467465 19.19 ENSDART00000189933
small muscle protein, X-linked
chr15_+_24644016 19.19 ENSDART00000043292
smoothelin, like
chr12_-_26415499 18.79 ENSDART00000185779
synaptopodin 2-like b
chr8_+_48613040 18.16 ENSDART00000121432
natriuretic peptide A
chr3_+_30257582 17.03 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr16_+_29650698 16.90 ENSDART00000137153
tropomodulin 4 (muscle)
chr15_+_20403903 15.96 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr13_+_22480857 15.64 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr11_+_36243774 15.09 ENSDART00000023323
zgc:172270
chr11_-_25213651 14.51 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr2_+_38039857 14.01 ENSDART00000159951
calsequestrin 1a
chr23_-_35756115 13.81 ENSDART00000043429
junctophilin 2
chr8_-_18535822 13.75 ENSDART00000100558
nexilin (F actin binding protein)
chr1_-_55810730 13.61 ENSDART00000100551
zgc:136908
chr9_-_42861080 13.61 ENSDART00000193688
titin, tandem duplicate 1
chr2_+_42191592 13.58 ENSDART00000144716
caveolae associated protein 4a
chr12_-_4683325 12.77 ENSDART00000152771
si:ch211-255p10.3
chr6_-_40722480 12.29 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr19_-_47555956 12.24 ENSDART00000114549
actin, alpha, cardiac muscle 1a
chr15_-_20933574 12.14 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr22_-_7050 11.32 ENSDART00000127829
ATPase family, AAA domain containing 3
chr6_-_15653494 11.05 ENSDART00000038133
tripartite motif containing 63a
chr10_+_22782522 11.03 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
chr20_-_29483514 10.78 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr6_-_1514767 10.70 ENSDART00000067586
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr8_+_50534948 10.69 ENSDART00000174435
phosphatidylethanolamine binding protein 4
chr23_-_45705525 10.45 ENSDART00000148959
endothelin receptor type Ab
chr19_+_712127 10.43 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
formin homology 2 domain containing 3a
chr18_+_8340886 10.03 ENSDART00000081132
carnitine palmitoyltransferase 1B (muscle)
chr11_+_42587900 9.97 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr23_+_42810055 9.81 ENSDART00000186647
myosin, light chain 9a, regulatory
chr11_-_11471857 9.72 ENSDART00000030103
keratin 94
chr21_+_5080789 9.65 ENSDART00000024199
ATP synthase F1 subunit alpha
chr5_-_68916455 9.52 ENSDART00000171465
ankyrin 1, erythrocytic a
chr3_-_32170850 9.48 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr10_+_6318227 9.45 ENSDART00000170872
ENSDART00000162428
ENSDART00000158994
tropomyosin 2 (beta)
chr19_-_32783373 9.44 ENSDART00000145790
5'-nucleotidase, cytosolic IAa
chr22_+_10201826 9.37 ENSDART00000006513
ENSDART00000132641
pyruvate dehydrogenase E1 beta subunit
chr21_+_15704556 9.36 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr6_-_39764995 9.26 ENSDART00000085277
phosphofructokinase, muscle b
chr6_-_10912424 9.24 ENSDART00000036456
cytochrome c, somatic b
chr25_+_3306620 9.11 ENSDART00000182085
ENSDART00000034704
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr6_-_10835849 9.11 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr15_+_24644251 9.03 ENSDART00000181660
smoothelin, like
chr3_+_24207243 8.91 ENSDART00000023454
ENSDART00000136400
adenylosuccinate lyase
chr1_-_58868306 8.68 ENSDART00000166615
dynamin 2b
chr25_+_29160102 8.55 ENSDART00000162854
pyruvate kinase M1/2b
chr18_+_27926839 8.53 ENSDART00000191835
homeodomain interacting protein kinase 3b
chr11_+_24313931 8.49 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr11_+_24314148 8.47 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr20_+_40150612 8.44 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr11_+_7158723 8.34 ENSDART00000035560
transmembrane protein 38A
chr10_+_22775253 8.32 ENSDART00000190141
transmembrane protein 88 a
chr4_-_25836684 8.27 ENSDART00000142491
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr8_-_14184423 8.12 ENSDART00000063817
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr16_-_17197546 8.07 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr12_-_4070058 8.04 ENSDART00000042200
aldolase a, fructose-bisphosphate, b
chr25_+_25124684 8.02 ENSDART00000167542
lactate dehydrogenase A4
chr12_-_47648538 7.92 ENSDART00000108477
fumarate hydratase
chr22_-_15593824 7.89 ENSDART00000123125
tropomyosin 4a
chr4_+_6572364 7.87 ENSDART00000122574
protein phosphatase 1, regulatory subunit 3Aa
chr16_-_560574 7.85 ENSDART00000148452
iroquois homeobox 2a
chr10_-_44017642 7.85 ENSDART00000135240
ENSDART00000014669
acyl-CoA dehydrogenase short chain
chr6_-_49898881 7.83 ENSDART00000150204
ATP synthase F1 subunit epsilon
chr8_-_17997845 7.78 ENSDART00000121660
acyl-CoA thioesterase 11b
chr15_+_404891 7.77 ENSDART00000155682
nipsnap homolog 2
chr18_-_226800 7.74 ENSDART00000165180
threonyl-tRNA synthetase-like 2
chr2_-_44199722 7.69 ENSDART00000140633
ENSDART00000145728
succinate dehydrogenase complex, subunit C, integral membrane protein
chr23_+_18722915 7.67 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr6_-_39765546 7.65 ENSDART00000185767
phosphofructokinase, muscle b
chr15_-_23645810 7.65 ENSDART00000168845
creatine kinase, muscle b
chr9_-_49493305 7.65 ENSDART00000148707
ENSDART00000148561
xin actin binding repeat containing 2b
chr9_+_54644626 7.65 ENSDART00000190609
EGF-like-domain, multiple 6
chr13_+_281214 7.48 ENSDART00000137572
mitochondrial pyruvate carrier 1
chr9_-_22821901 7.42 ENSDART00000101711
nebulin
chr10_-_39153959 7.36 ENSDART00000150193
ENSDART00000111362
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr14_-_34771371 7.33 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr9_-_710896 7.22 ENSDART00000180478
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr20_+_54738210 7.20 ENSDART00000151399
p21 protein (Cdc42/Rac)-activated kinase 7
chr23_+_5524247 7.20 ENSDART00000189679
ENSDART00000083622
TEA domain family member 3 a
chr19_-_32487469 7.06 ENSDART00000050130
guanosine monophosphate reductase
chr3_-_16010968 6.94 ENSDART00000080672
mitochondrial ribosomal protein S34
chr18_-_16791331 6.93 ENSDART00000148222
adenosine monophosphate deaminase 3b
chr4_+_38344 6.91 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr14_-_29799993 6.86 ENSDART00000133775
ENSDART00000005568
PDZ and LIM domain 3b
chr9_+_2333927 6.60 ENSDART00000123340
ATP synthase membrane subunit c locus 3a
chr16_+_30961822 6.58 ENSDART00000059187
glutathione S-transferase kappa 2
chr13_-_37254777 6.55 ENSDART00000139734
spectrin repeat containing, nuclear envelope 2b
chr14_+_30340251 6.49 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr8_+_14158021 6.44 ENSDART00000080832
si:dkey-6n6.2
chr18_+_36037223 6.42 ENSDART00000144410
transmembrane protein 91
chr9_-_34945566 6.41 ENSDART00000131908
ENSDART00000059861
DCN1, defective in cullin neddylation 1, domain containing 2a
chr25_-_31396479 6.37 ENSDART00000156828
proline rich 33
chr12_-_29305533 6.36 ENSDART00000189410
SH2 domain containing 4Bb
chr19_+_41169996 6.34 ENSDART00000048438
ankyrin repeat and SOCS box containing 4
chr6_-_49873020 6.30 ENSDART00000148511
GNAS complex locus
chr23_+_18722715 6.30 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr6_+_41463786 6.25 ENSDART00000065006
twinfilin actin-binding protein 2a
chr7_-_22941472 5.98 ENSDART00000190334
TNF superfamily member 10, like
chr3_-_18410968 5.97 ENSDART00000041842
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr8_-_17980317 5.97 ENSDART00000129148
TNNI3 interacting kinase
chr14_-_12253309 5.93 ENSDART00000115101
myotilin
chr17_+_53424415 5.90 ENSDART00000157022
solute carrier family 9 member A1b
chr24_+_25471196 5.90 ENSDART00000066625
small muscle protein, X-linked
chr20_+_1996202 5.88 ENSDART00000184143

chr14_-_17121676 5.85 ENSDART00000170154
ENSDART00000060479
smoothelin-like 1
chr14_+_33413980 5.84 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr9_+_30464641 5.82 ENSDART00000128357
gap junction protein, alpha 5a
chr3_-_12187245 5.80 ENSDART00000189553
ENSDART00000165131
sarcalumenin
chr14_-_33454595 5.73 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr8_+_25733872 5.72 ENSDART00000156340
si:ch211-167b20.8
chr9_-_23944470 5.72 ENSDART00000138754
collagen, type VI, alpha 3
chr22_-_26595027 5.71 ENSDART00000184162

chr12_-_34827477 5.66 ENSDART00000153026
si:dkey-21c1.6
chr2_-_48753873 5.57 ENSDART00000189556

chr4_-_4932619 5.56 ENSDART00000103293
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr23_-_35069805 5.52 ENSDART00000087219

chr9_-_22822084 5.45 ENSDART00000142020
nebulin
chr7_-_51793333 5.40 ENSDART00000180654

chr1_+_23783349 5.40 ENSDART00000007531
slit homolog 2 (Drosophila)
chr3_+_20001608 5.40 ENSDART00000137944
ankyrin repeat and SOCS box containing 16
chr13_+_22249636 5.35 ENSDART00000108472
ENSDART00000173123
synaptopodin 2-like a
chr25_+_19008497 5.35 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr18_+_30508729 5.28 ENSDART00000185140
cytochrome c oxidase subunit IV isoform 1
chr13_+_24853578 5.27 ENSDART00000145865
si:dkey-24f15.2
chr2_-_15318786 5.22 ENSDART00000135851
trans-2,3-enoyl-CoA reductase-like 2b
chr22_-_15587360 5.20 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr10_-_39154594 5.18 ENSDART00000148825
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr24_-_23974559 5.18 ENSDART00000080510
ENSDART00000135242
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4
chr17_-_38778826 5.17 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
D-glutamate cyclase
chr13_+_28821841 5.17 ENSDART00000179900

chr20_+_19066596 5.12 ENSDART00000130271
SRY (sex determining region Y)-box 7
chr21_-_23035120 5.12 ENSDART00000016502
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr12_-_29305220 5.02 ENSDART00000153458
SH2 domain containing 4Bb
chr12_-_20373058 5.00 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr22_+_19473804 4.93 ENSDART00000135085
ENSDART00000147673
ENSDART00000156818
si:dkey-78l4.7
chr17_+_135590 4.86 ENSDART00000166339
kelch domain containing 2
chr22_+_19247255 4.79 ENSDART00000144053
si:dkey-21e2.10
chr7_+_65586624 4.77 ENSDART00000184344
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr16_+_32736588 4.77 ENSDART00000075191
ENSDART00000168358
zgc:172323
chr23_+_17417539 4.75 ENSDART00000182605

chr17_-_17764801 4.74 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr7_-_41851605 4.72 ENSDART00000142981
myosin light chain kinase 3
chr20_-_23254876 4.71 ENSDART00000141510
OCIA domain containing 1
chr4_-_16451375 4.68 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr5_-_69316142 4.67 ENSDART00000157238
ENSDART00000144570
smoothelin b
chr13_+_50375800 4.63 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr18_+_30507839 4.62 ENSDART00000026866
cytochrome c oxidase subunit IV isoform 1
chr4_+_2620751 4.62 ENSDART00000013924
G protein-coupled receptor 22a
chr9_-_21067971 4.59 ENSDART00000004333
T-box 15
chr8_+_2530065 4.54 ENSDART00000063943
mitochondrial ribosomal protein L40
chr19_+_9212031 4.52 ENSDART00000052930
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr6_+_52804267 4.52 ENSDART00000065681
matrilin 4
chr17_-_31058664 4.52 ENSDART00000126414
echinoderm microtubule associated protein like 1
chr8_-_979735 4.49 ENSDART00000149612
zinc finger protein 366
chr21_-_20381481 4.44 ENSDART00000115236
ATP synthase membrane subunit ea
chr23_-_9919959 4.42 ENSDART00000127029
si:ch211-220i18.4
chr19_+_30990815 4.42 ENSDART00000134645
syncoilin, intermediate filament protein
chr25_-_29134654 4.40 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr12_+_49125510 4.38 ENSDART00000185804

chr23_+_44611864 4.30 ENSDART00000145905
ENSDART00000132361
enolase 3, (beta, muscle)
chr1_-_59232267 4.27 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr11_+_77526 4.24 ENSDART00000193521

chr11_-_7410537 4.24 ENSDART00000009859
adhesion G protein-coupled receptor L4
chr12_-_47782623 4.23 ENSDART00000115742
selenoprotein U1b
chr1_-_9109699 4.22 ENSDART00000147833
vascular associated protein
chr1_+_580642 4.15 ENSDART00000147633
mitochondrial ribosomal protein L39
chr22_+_19266995 4.15 ENSDART00000133995
ENSDART00000144963
si:dkey-21e2.12
chr21_+_10866421 4.14 ENSDART00000137858
alpha-kinase 2
chr13_-_13751017 4.04 ENSDART00000180182
kyphoscoliosis peptidase
chr15_+_21882419 4.01 ENSDART00000157216
si:dkey-103g5.4
chr11_+_21076872 4.00 ENSDART00000155521
proline/arginine-rich end leucine-rich repeat protein
chr5_+_36439405 3.98 ENSDART00000102973
ectodysplasin A
chr5_-_46980651 3.98 ENSDART00000181022
ENSDART00000168038
EGF-like repeats and discoidin I-like domains 3a
chr16_-_32006737 3.97 ENSDART00000184813
ENSDART00000179827
glutathione S-transferase kappa 4
chr23_-_27571667 3.94 ENSDART00000008174
phosphofructokinase, muscle a
chr9_-_43142636 3.89 ENSDART00000134349
ENSDART00000181835
coiled-coil domain containing 141
chr25_-_13363286 3.88 ENSDART00000163735
ENSDART00000169119
NDRG family member 4
chr6_-_15096556 3.83 ENSDART00000185327
four and a half LIM domains 2b
chr23_+_42813415 3.81 ENSDART00000055577
myosin, light chain 9a, regulatory
chr8_+_15251448 3.78 ENSDART00000063717
zgc:171480
chr2_-_44255537 3.78 ENSDART00000011188
ENSDART00000093298
ATPase Na+/K+ transporting subunit alpha 2
chr6_+_28124393 3.77 ENSDART00000089195
G protein-coupled receptor 17
chr3_+_27770110 3.74 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr5_-_18007077 3.74 ENSDART00000129878
zinc finger, DHHC-type containing 8b
chr3_-_32590164 3.74 ENSDART00000151151
tetraspanin 4b
chr16_-_2818170 3.71 ENSDART00000081918
acyl-CoA thioesterase 22
chr24_+_2470061 3.70 ENSDART00000140383
ENSDART00000191261
coagulation factor XIII A chain
chr18_+_48423973 3.69 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr12_-_28983584 3.68 ENSDART00000112374
zgc:171713
chr3_+_58167288 3.68 ENSDART00000155874
ENSDART00000010395
ubiquinol-cytochrome c reductase core protein 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of rargb_pparab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.2 GO:1905072 cardiac jelly development(GO:1905072)
4.7 14.0 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
4.5 13.6 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
3.9 19.3 GO:0003210 cardiac atrium formation(GO:0003210)
3.8 22.8 GO:0003272 endocardial cushion formation(GO:0003272)
3.7 87.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.4 17.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
2.9 8.8 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
2.8 17.0 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
2.8 8.3 GO:2000726 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
2.8 16.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
2.7 13.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
2.1 12.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
2.0 13.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.0 7.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.9 48.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.8 5.4 GO:0007414 axonal defasciculation(GO:0007414)
1.7 12.0 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
1.6 14.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.5 4.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.5 15.1 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
1.4 9.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.3 18.3 GO:0048769 sarcomerogenesis(GO:0048769)
1.3 16.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 5.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.3 3.8 GO:0065001 specification of axis polarity(GO:0065001)
1.2 12.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.2 23.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
1.2 3.6 GO:0036363 transforming growth factor beta activation(GO:0036363)
1.1 6.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.0 3.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
1.0 5.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
1.0 12.9 GO:0046085 adenosine metabolic process(GO:0046085)
1.0 8.9 GO:0006167 AMP biosynthetic process(GO:0006167)
1.0 4.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.9 2.8 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.9 9.3 GO:0006108 malate metabolic process(GO:0006108)
0.9 2.7 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.9 2.7 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.8 2.5 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.8 20.5 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.8 22.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.8 1.6 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.8 4.8 GO:0006574 valine catabolic process(GO:0006574)
0.7 3.0 GO:0099625 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.7 2.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.7 2.7 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.6 1.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.6 2.4 GO:0070317 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.6 6.0 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.6 13.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.6 5.1 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.6 3.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 12.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 4.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.5 24.7 GO:0022900 electron transport chain(GO:0022900)
0.5 2.1 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.5 3.1 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.5 2.1 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.5 0.5 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.5 2.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.5 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.5 10.8 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.5 17.1 GO:0006096 glycolytic process(GO:0006096)
0.5 2.3 GO:0045124 regulation of bone resorption(GO:0045124)
0.5 4.1 GO:1901998 toxin transport(GO:1901998)
0.5 2.3 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.5 8.1 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.4 0.9 GO:0072020 proximal straight tubule development(GO:0072020)
0.4 4.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.4 1.7 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.4 7.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 2.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.4 2.5 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 2.9 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.4 2.4 GO:0005513 detection of calcium ion(GO:0005513)
0.4 2.4 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.4 1.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.4 1.6 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 9.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.4 2.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.4 1.1 GO:0042245 RNA repair(GO:0042245)
0.4 2.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 5.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 1.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 1.4 GO:1990697 protein depalmitoleylation(GO:1990697)
0.4 5.3 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.4 1.8 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.4 15.1 GO:0060840 artery development(GO:0060840)
0.3 10.8 GO:0035329 hippo signaling(GO:0035329)
0.3 1.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 1.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 0.3 GO:0001659 temperature homeostasis(GO:0001659)
0.3 61.6 GO:0060538 skeletal muscle organ development(GO:0060538)
0.3 2.3 GO:0006833 water transport(GO:0006833)
0.3 1.3 GO:0035790 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.3 3.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 6.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 1.0 GO:0035992 tendon formation(GO:0035992)
0.3 1.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) regulation of mitophagy(GO:1903146)
0.3 0.3 GO:0086001 cardiac muscle cell action potential(GO:0086001)
0.3 4.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.3 1.2 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.3 1.9 GO:0060976 coronary vasculature development(GO:0060976)
0.3 44.5 GO:0006936 muscle contraction(GO:0006936)
0.3 9.7 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.3 1.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 0.6 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.3 1.1 GO:0021800 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.3 3.9 GO:0060038 striated muscle cell proliferation(GO:0014855) cardiac muscle cell proliferation(GO:0060038)
0.3 0.8 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 0.5 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.3 6.7 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.3 1.3 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.2 3.2 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 2.7 GO:0050909 sensory perception of taste(GO:0050909)
0.2 1.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 1.7 GO:0097009 energy homeostasis(GO:0097009)
0.2 7.4 GO:0051014 actin filament severing(GO:0051014)
0.2 1.2 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.2 0.7 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 0.9 GO:0090148 membrane fission(GO:0090148)
0.2 1.8 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 1.4 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.2 1.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 1.6 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.2 30.0 GO:0006821 chloride transport(GO:0006821)
0.2 1.6 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 4.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.3 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.2 1.8 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.2 2.2 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 1.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 2.2 GO:0098659 inorganic cation import into cell(GO:0098659) inorganic ion import into cell(GO:0099587)
0.2 1.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 4.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 0.4 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.2 1.7 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 2.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 0.6 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.8 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 0.8 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.8 GO:0021576 hindbrain formation(GO:0021576)
0.2 1.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 0.6 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2 1.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.8 GO:0048331 axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327) axial mesoderm structural organization(GO:0048331) mesoderm structural organization(GO:0048338)
0.2 0.8 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 2.1 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 1.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 2.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 5.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.7 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 1.5 GO:0044211 CTP salvage(GO:0044211)
0.2 1.3 GO:0006552 leucine catabolic process(GO:0006552)
0.2 3.1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.2 1.3 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 0.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.4 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 3.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444) mitochondrial calcium ion homeostasis(GO:0051560)
0.2 0.7 GO:0033605 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 0.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.2 0.4 GO:0030238 male sex determination(GO:0030238)
0.2 1.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.0 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 0.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.5 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.2 1.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.2 2.5 GO:0045116 protein neddylation(GO:0045116)
0.2 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.2 1.0 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.2 4.9 GO:0042476 odontogenesis(GO:0042476)
0.2 0.3 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.2 2.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.2 1.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 5.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 4.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 1.2 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.1 0.7 GO:0043029 T cell homeostasis(GO:0043029)
0.1 1.9 GO:0046545 development of primary female sexual characteristics(GO:0046545)
0.1 2.8 GO:0030168 platelet activation(GO:0030168)
0.1 0.8 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 7.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 2.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 1.0 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 5.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 11.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 2.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.6 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 7.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 4.4 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 2.8 GO:0001935 endothelial cell proliferation(GO:0001935)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.6 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 1.7 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 4.7 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.1 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.8 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.7 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 2.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 1.3 GO:0009648 photoperiodism(GO:0009648)
0.1 1.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.8 GO:0045444 fat cell differentiation(GO:0045444)
0.1 2.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 7.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 0.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 2.2 GO:0060973 cell migration involved in heart development(GO:0060973)
0.1 1.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 7.5 GO:0001666 response to hypoxia(GO:0001666)
0.1 2.5 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 3.6 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 0.5 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952) ketone body metabolic process(GO:1902224)
0.1 1.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.6 GO:0032218 riboflavin transport(GO:0032218)
0.1 3.0 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 3.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.2 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.7 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.4 GO:0009408 response to heat(GO:0009408)
0.1 0.4 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 1.5 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 3.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 5.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.4 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 1.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.6 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.4 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 2.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 8.8 GO:0055001 muscle cell development(GO:0055001)
0.1 1.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.2 GO:0005991 disaccharide metabolic process(GO:0005984) trehalose metabolic process(GO:0005991)
0.1 1.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 2.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.8 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 4.4 GO:0007098 centrosome cycle(GO:0007098)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.9 GO:0043542 endothelial cell migration(GO:0043542)
0.1 1.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 1.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.4 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 2.1 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.2 GO:0006867 asparagine transport(GO:0006867)
0.1 19.6 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.6 GO:0019985 translesion synthesis(GO:0019985)
0.1 2.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.7 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.4 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932) clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 5.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 1.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 4.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.6 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:1901386 negative regulation of calcium ion transmembrane transporter activity(GO:1901020) negative regulation of voltage-gated calcium channel activity(GO:1901386) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 2.3 GO:0007602 phototransduction(GO:0007602)
0.0 4.6 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.5 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 0.2 GO:0060876 semicircular canal formation(GO:0060876)
0.0 1.3 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.8 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 4.5 GO:0007005 mitochondrion organization(GO:0007005)
0.0 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 2.1 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0071711 basement membrane organization(GO:0071711)
0.0 2.0 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.4 GO:0016444 somatic cell DNA recombination(GO:0016444)
0.0 0.0 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.7 GO:0050821 protein stabilization(GO:0050821)
0.0 0.6 GO:0046503 glycerolipid catabolic process(GO:0046503)
0.0 1.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.8 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.9 GO:0001708 cell fate specification(GO:0001708)
0.0 3.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.0 GO:0032835 glomerulus development(GO:0032835)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 1.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.8 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 12.2 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.6 GO:0045165 cell fate commitment(GO:0045165)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0045823 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460) positive regulation of heart contraction(GO:0045823)
0.0 0.2 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0050921 positive regulation of chemotaxis(GO:0050921) regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.7 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0072073 nephron epithelium development(GO:0072009) kidney epithelium development(GO:0072073)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 25.6 GO:0043034 costamere(GO:0043034)
3.4 13.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.3 23.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.8 17.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.8 13.8 GO:0030314 junctional membrane complex(GO:0030314)
2.4 7.1 GO:1902560 GMP reductase complex(GO:1902560)
2.0 9.9 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.9 20.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.9 13.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.7 25.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.7 3.3 GO:0035253 ciliary rootlet(GO:0035253)
1.6 31.1 GO:0031430 M band(GO:0031430)
1.5 62.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.5 40.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
1.4 23.0 GO:0005869 dynactin complex(GO:0005869)
1.3 5.1 GO:0097268 cytoophidium(GO:0097268)
1.3 58.9 GO:0031941 filamentous actin(GO:0031941)
1.2 12.8 GO:0061617 MICOS complex(GO:0061617)
1.1 8.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.9 2.6 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.8 13.6 GO:0030017 sarcomere(GO:0030017)
0.8 16.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.8 11.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.8 43.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.7 2.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.7 1.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.7 53.8 GO:0030018 Z disc(GO:0030018)
0.6 2.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 9.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 4.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.5 21.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.5 6.5 GO:0005922 connexon complex(GO:0005922)
0.5 4.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 60.9 GO:0016459 myosin complex(GO:0016459)
0.5 2.9 GO:0000801 central element(GO:0000801)
0.5 1.4 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 9.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 2.1 GO:0033503 HULC complex(GO:0033503)
0.4 7.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 2.0 GO:0008091 spectrin(GO:0008091)
0.4 2.3 GO:0070062 extracellular exosome(GO:0070062)
0.4 24.7 GO:0034707 chloride channel complex(GO:0034707)
0.4 12.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.4 3.2 GO:1990246 uniplex complex(GO:1990246)
0.4 8.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 14.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.3 3.4 GO:0070449 elongin complex(GO:0070449)
0.3 4.6 GO:0030056 hemidesmosome(GO:0030056)
0.3 15.5 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.3 4.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 7.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 10.5 GO:0016605 PML body(GO:0016605)
0.3 2.6 GO:0042583 chromaffin granule(GO:0042583)
0.3 1.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.2 5.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.6 GO:0031045 dense core granule(GO:0031045)
0.2 1.8 GO:0072487 MSL complex(GO:0072487)
0.2 0.7 GO:0097541 axonemal basal plate(GO:0097541)
0.2 1.1 GO:0097224 sperm connecting piece(GO:0097224)
0.2 0.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.6 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.5 GO:0070469 respiratory chain(GO:0070469)
0.2 0.9 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.2 2.5 GO:0070187 telosome(GO:0070187)
0.2 14.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 22.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 1.5 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 10.4 GO:0005884 actin filament(GO:0005884)
0.1 1.5 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 7.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.0 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 1.2 GO:0032021 NELF complex(GO:0032021)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.7 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.6 GO:0005771 multivesicular body(GO:0005771)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 3.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.6 GO:0043209 myelin sheath(GO:0043209)
0.1 2.7 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 7.1 GO:0005882 intermediate filament(GO:0005882)
0.1 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 6.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.1 GO:0032421 stereocilium bundle(GO:0032421)
0.1 4.6 GO:0042383 sarcolemma(GO:0042383)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 5.7 GO:0005814 centriole(GO:0005814)
0.1 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 11.2 GO:0005840 ribosome(GO:0005840)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 9.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 2.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.4 GO:0034704 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.1 1.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.6 GO:0005604 basement membrane(GO:0005604)
0.1 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 1.8 GO:0034703 cation channel complex(GO:0034703)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 2.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 38.6 GO:0005829 cytosol(GO:0005829)
0.0 16.3 GO:0005739 mitochondrion(GO:0005739)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.1 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 22.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 66.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.3 9.9 GO:0000104 succinate dehydrogenase activity(GO:0000104)
2.6 12.8 GO:0016531 copper chaperone activity(GO:0016531)
2.4 17.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
2.4 47.6 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
2.4 7.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
2.2 8.9 GO:0016842 amidine-lyase activity(GO:0016842)
2.1 23.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.0 8.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.9 20.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.8 19.3 GO:0032036 myosin heavy chain binding(GO:0032036)
1.6 10.9 GO:0004962 endothelin receptor activity(GO:0004962)
1.5 6.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4 8.6 GO:0004743 pyruvate kinase activity(GO:0004743)
1.4 30.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.3 3.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.3 8.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.3 5.1 GO:0003883 CTP synthase activity(GO:0003883)
1.3 6.3 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.2 9.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
1.2 4.8 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
1.2 33.1 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.1 6.8 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
1.1 3.2 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.0 22.9 GO:0005523 tropomyosin binding(GO:0005523)
1.0 8.7 GO:0015250 water channel activity(GO:0015250)
0.9 13.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.9 2.6 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.8 19.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.7 11.2 GO:2001069 glycogen binding(GO:2001069)
0.7 14.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 3.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.7 4.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 3.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 9.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 3.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.6 20.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.6 3.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.6 2.9 GO:0015288 porin activity(GO:0015288)
0.6 4.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.5 2.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 4.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 3.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 1.5 GO:0048030 disaccharide binding(GO:0048030)
0.5 1.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 4.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 2.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 2.3 GO:0008097 5S rRNA binding(GO:0008097)
0.5 6.5 GO:0005243 gap junction channel activity(GO:0005243)
0.4 4.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 2.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 1.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.4 1.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.4 0.9 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.4 3.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 2.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 2.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.4 153.1 GO:0051015 actin filament binding(GO:0051015)
0.4 1.2 GO:0044548 S100 protein binding(GO:0044548)
0.4 4.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 1.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 1.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 3.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 1.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.4 1.4 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.4 2.1 GO:0004966 galanin receptor activity(GO:0004966)
0.4 4.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.4 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 5.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 24.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 2.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 4.6 GO:0030506 ankyrin binding(GO:0030506)
0.3 17.1 GO:0005178 integrin binding(GO:0005178)
0.3 1.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.3 5.7 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.3 2.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 25.4 GO:0005254 chloride channel activity(GO:0005254)
0.3 1.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 9.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 2.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 1.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 4.4 GO:0005123 death receptor binding(GO:0005123)
0.3 2.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 1.1 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.3 8.2 GO:0030165 PDZ domain binding(GO:0030165)
0.3 3.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 15.4 GO:0051427 hormone receptor binding(GO:0051427)
0.3 4.1 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.7 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 1.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 2.5 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.7 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 6.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.1 GO:0060182 apelin receptor activity(GO:0060182)
0.2 3.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 64.0 GO:0003779 actin binding(GO:0003779)
0.2 5.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 4.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 1.6 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 1.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.2 1.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.8 GO:0008494 translation activator activity(GO:0008494)
0.2 1.4 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.2 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 7.4 GO:0051087 chaperone binding(GO:0051087)
0.2 3.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.5 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.2 2.4 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 0.7 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.2 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.3 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.2 1.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 2.0 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 3.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.2 8.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 2.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 8.2 GO:0009975 cyclase activity(GO:0009975)
0.2 2.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.6 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 0.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 7.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.1 4.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 24.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.8 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 9.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 2.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.1 0.7 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 2.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 2.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.8 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 5.6 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) excitatory extracellular ligand-gated ion channel activity(GO:0005231) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.4 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 1.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.5 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.2 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 1.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.5 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 7.9 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.7 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 9.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.1 GO:0003823 antigen binding(GO:0003823)
0.1 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.5 GO:0044325 ion channel binding(GO:0044325)
0.1 0.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.1 2.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.9 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 1.2 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 7.3 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 8.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159) protein complex scaffold(GO:0032947)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 6.3 GO:0042802 identical protein binding(GO:0042802)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 1.2 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 8.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 11.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0015301 anion:anion antiporter activity(GO:0015301)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 13.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 14.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 15.5 PID AP1 PATHWAY AP-1 transcription factor network
0.3 6.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 2.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 5.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 2.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 12.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 5.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 97.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.2 11.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
1.2 14.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 15.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1 31.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.0 14.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.9 8.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.8 12.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.8 15.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.8 11.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.8 2.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 7.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 8.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.6 12.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 8.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.5 3.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.4 4.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 2.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 2.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 4.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 2.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 2.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 3.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 9.6 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.2 2.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 7.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 1.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 2.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 2.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 17.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 1.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 3.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins