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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rarga

Z-value: 1.99

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Transcription factors associated with rarga

Gene Symbol Gene ID Gene Info
ENSDARG00000034117 retinoic acid receptor gamma a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rargadr11_v1_chr23_+_35918530_35918530-0.881.4e-31Click!

Activity profile of rarga motif

Sorted Z-values of rarga motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_42234484 42.91 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apolipoprotein M
chr13_-_12660318 31.21 ENSDART00000008498
alcohol dehydrogenase 8a
chr5_+_28830388 30.77 ENSDART00000149150
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_+_37201483 30.70 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
chr16_-_17197546 29.83 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr4_-_17409533 29.54 ENSDART00000011943
phenylalanine hydroxylase
chr5_-_41531629 27.42 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr7_+_52122224 26.80 ENSDART00000174268
cytochrome P450, family 2, subfamily X, polypeptide 12
chr20_+_31269778 25.36 ENSDART00000133353
apolipoprotein Bb, tandem duplicate 1
chr13_-_22862133 24.34 ENSDART00000138563
phenazine biosynthesis-like protein domain containing 2
chr8_+_1769475 24.07 ENSDART00000079073
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr21_-_30658509 23.75 ENSDART00000139764
si:dkey-22f5.9
chr13_-_22843562 23.40 ENSDART00000142738
phenazine biosynthesis like protein domain containing
chr25_-_26018424 22.87 ENSDART00000089332
acyl-CoA synthetase bubblegum family member 1
chr22_-_23781083 22.81 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
complement factor H like 3
chr3_-_15080226 22.61 ENSDART00000109818
ENSDART00000139835
NME/NM23 nucleoside diphosphate kinase 4
chr12_-_6172154 21.31 ENSDART00000185434
apobec1 complementation factor
chr20_+_6142433 21.26 ENSDART00000054084
ENSDART00000136986
transthyretin (prealbumin, amyloidosis type I)
chr8_+_19514294 18.08 ENSDART00000170622
si:ch73-281k2.5
chr6_-_8498908 15.52 ENSDART00000149222
peptidoglycan recognition protein 2
chr16_+_25126935 15.50 ENSDART00000058945
zgc:92590
chr2_+_51028269 15.49 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr2_-_20120904 14.29 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr2_-_24289641 13.38 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr6_-_8498676 13.23 ENSDART00000148627
peptidoglycan recognition protein 2
chr17_-_2584423 13.17 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr13_-_4707018 12.99 ENSDART00000128422
oncoprotein induced transcript 3
chr25_+_3327071 12.87 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr14_-_36412473 12.77 ENSDART00000128244
ENSDART00000138376
ankyrin repeat and SOCS box containing 5a
chr12_-_29301022 12.77 ENSDART00000187826
SH2 domain containing 4Bb
chr7_+_52135791 12.73 ENSDART00000098705
cytochrome P450, family 2, subfamily X, polypeptide 12
chr22_-_24967348 12.07 ENSDART00000153490
ENSDART00000084871
family with sequence similarity 20, member C like
chr25_-_29415369 11.03 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr13_+_22480857 11.02 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr25_+_3326885 10.61 ENSDART00000104866
lactate dehydrogenase Bb
chr5_+_19343880 10.53 ENSDART00000148130
acetyl-CoA carboxylase beta
chr9_-_43082945 10.48 ENSDART00000142257
coiled-coil domain containing 141
chr6_-_49898881 10.47 ENSDART00000150204
ATP synthase F1 subunit epsilon
chr9_+_24095677 10.16 ENSDART00000150443
leucine rich repeat (in FLII) interacting protein 1a
chr24_-_9989634 10.12 ENSDART00000115275
zgc:152652
chr6_-_15653494 10.11 ENSDART00000038133
tripartite motif containing 63a
chr17_-_2590222 9.90 ENSDART00000185711

chr2_-_57469115 9.79 ENSDART00000192201
protein inhibitor of activated STAT, 4b
chr22_-_17595310 9.70 ENSDART00000099056
glutathione peroxidase 4a
chr5_-_64168415 9.65 ENSDART00000048395
cardiac myosin light chain-1
chr13_+_22480496 9.44 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr2_-_48826707 9.38 ENSDART00000134711
supervillin b
chr10_+_28428222 9.36 ENSDART00000135003
si:ch211-222e20.4
chr24_-_9979342 9.14 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr8_+_8046086 9.05 ENSDART00000163232
ENSDART00000111392
ATP-binding cassette, sub-family D (ALD), member 1
chr9_-_1970071 8.85 ENSDART00000080608
homeobox D10a
chr19_+_40856807 8.70 ENSDART00000139083
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr22_-_18779232 8.58 ENSDART00000186726
ATP synthase F1 subunit delta
chr6_-_20952187 8.32 ENSDART00000074327
insulin-like growth factor binding protein 2a
chr6_-_43047774 8.08 ENSDART00000161722
glycerate kinase
chr1_-_58913813 8.08 ENSDART00000056494
zgc:171687
chr17_-_15498275 7.97 ENSDART00000156905
ENSDART00000080661
si:ch211-266g18.10
chr19_-_14155781 7.61 ENSDART00000169232
nuclear receptor subfamily 0, group B, member 2b
chr6_+_28054639 7.50 ENSDART00000187478
ENSDART00000189194
si:ch73-194h10.2
chr5_+_25585869 7.41 ENSDART00000138060
si:dkey-229d2.7
chr10_-_16028082 7.38 ENSDART00000122540
aldehyde dehydrogenase 7 family, member A1
chr4_+_9836465 7.29 ENSDART00000004879
heat shock protein 90, beta (grp94), member 1
chr24_-_14711597 7.27 ENSDART00000131830
junctophilin 1a
chr22_-_18778988 7.08 ENSDART00000019235
ATP synthase F1 subunit delta
chr15_+_3284416 6.97 ENSDART00000187665
ENSDART00000171723
forkhead box O1 a
chr22_-_38258053 6.83 ENSDART00000132516
ELAV like neuron-specific RNA binding protein 2
chr21_-_43117327 6.82 ENSDART00000122352
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr15_+_46386261 6.72 ENSDART00000191793
immunoglobulin superfamily member 11
chr23_+_36087219 6.66 ENSDART00000154825
homeobox C3a
chr19_+_40856534 6.59 ENSDART00000051950
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_-_10835849 6.43 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr6_-_40448416 6.42 ENSDART00000187019
ENSDART00000179469
TatD DNase domain containing 2
chr17_+_6538733 6.41 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr24_+_19986432 6.38 ENSDART00000184402

chr19_-_703898 6.13 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr4_-_9836342 6.10 ENSDART00000150519
tetratricopeptide repeat domain 41
chr7_-_16237861 6.08 ENSDART00000173647
bloodthirsty-related gene family, member 7
chr7_-_27033080 5.94 ENSDART00000173516
nucleobindin 2a
chr12_+_46605600 5.92 ENSDART00000123533
fatty acid desaturase 6
chr3_-_3210640 5.89 ENSDART00000187699
si:ch211-229i14.2
chr7_-_16205471 5.87 ENSDART00000173584
bloodthirsty-related gene family, member 5
chr13_+_38817871 5.87 ENSDART00000187708
collagen, type XIX, alpha 1
chr21_-_308852 5.86 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr22_+_28969071 5.79 ENSDART00000163427
Pim proto-oncogene, serine/threonine kinase, related 95
chr15_-_36727462 5.73 ENSDART00000085971
nephrosis 1, congenital, Finnish type (nephrin)
chr19_+_30867845 5.69 ENSDART00000047461
major facilitator superfamily domain containing 2ab
chr25_-_37284370 5.63 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr9_-_22834860 5.59 ENSDART00000146486
nebulin
chr25_-_17367578 5.57 ENSDART00000064591
ENSDART00000110692
cytochrome P450, family 2, subfamily X, polypeptide 6
chr1_-_52167509 5.56 ENSDART00000184935

chr1_+_56886214 5.50 ENSDART00000152718
ENSDART00000182408
si:ch211-1f22.8
chr25_-_17368231 5.46 ENSDART00000189291
cytochrome P450, family 2, subfamily X, polypeptide 6
chr15_-_30853246 5.43 ENSDART00000112511
A kinase (PRKA) anchor protein 1b
chr20_+_572037 5.37 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr22_-_5171829 5.34 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr24_-_17047918 5.25 ENSDART00000020204
methionine sulfoxide reductase B2
chr16_+_16978424 5.25 ENSDART00000143128
ribosomal protein L18
chr14_+_32918484 5.20 ENSDART00000105721
ligand of numb-protein X 2b
chr17_+_26352372 5.10 ENSDART00000155177
glutamate receptor, ionotropic, delta 1a
chr16_+_32736588 4.99 ENSDART00000075191
ENSDART00000168358
zgc:172323
chr10_+_26813710 4.99 ENSDART00000136122
si:ch211-263p13.7
chr14_+_32918172 4.97 ENSDART00000182867
ligand of numb-protein X 2b
chr1_-_46632948 4.90 ENSDART00000148893
ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr13_+_22264914 4.86 ENSDART00000060576
myozenin 1a
chr8_-_13419049 4.82 ENSDART00000133656
Pim proto-oncogene, serine/threonine kinase, related 101
chr6_+_49021703 4.82 ENSDART00000149394
solute carrier family 16 (monocarboxylate transporter), member 1a
chr19_-_48349002 4.72 ENSDART00000168468
si:ch73-359m17.8
chr17_-_32370047 4.72 ENSDART00000145487
Kruppel-like factor 11b
chr20_-_28956303 4.68 ENSDART00000062342
acyl-CoA thioesterase 21
chr22_+_29009541 4.68 ENSDART00000169449
Pim proto-oncogene, serine/threonine kinase, related 97
chr21_-_551014 4.64 ENSDART00000099252
vimentin-related 1
chr1_+_54626491 4.61 ENSDART00000136063
si:ch211-202h22.9
chr9_-_21459074 4.58 ENSDART00000136427
zinc finger, MYM-type 2
chr11_-_37720266 4.57 ENSDART00000142734
YOD1 deubiquitinase
chr8_-_13471916 4.55 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr18_-_22753637 4.54 ENSDART00000181589
ENSDART00000009912
heat shock transcription factor 4
chr15_-_24883956 4.41 ENSDART00000113199
aryl hydrocarbon receptor interacting protein-like 1
chr21_-_5879897 4.39 ENSDART00000184034
ribosomal protein L35
chr7_-_63637644 4.37 ENSDART00000145168
si:ch211-208g1.1
chr8_-_13428740 4.34 ENSDART00000131826

chr22_+_29067388 4.25 ENSDART00000133673
Pim proto-oncogene, serine/threonine kinase, related 100
chr7_-_23768234 4.23 ENSDART00000173981
si:ch211-200p22.4
chr8_-_35736141 4.10 ENSDART00000190863

chr1_+_44767657 4.07 ENSDART00000073717
si:dkey-9i23.4
chr13_+_24579108 4.07 ENSDART00000001830
enoyl CoA hydratase, short chain, 1, mitochondrial
chr25_+_34887999 4.03 ENSDART00000012287
ENSDART00000182506
ENSDART00000183561
spire-type actin nucleation factor 2
chr20_+_23960525 3.93 ENSDART00000042123
connexin 52.6
chr6_+_43390387 3.90 ENSDART00000122793
microphthalmia-associated transcription factor a
chr6_+_52235441 3.85 ENSDART00000056319
cytochrome c oxidase subunit VIc
chr15_-_19681870 3.85 ENSDART00000152266
si:dkey-4p15.4
chr20_+_33534038 3.84 ENSDART00000029206
potassium voltage-gated channel, subfamily F, member 1a
chr1_-_55118745 3.80 ENSDART00000133915
SERTA domain containing 2a
chr8_+_41712799 3.79 ENSDART00000150337
si:ch211-208g1.1
chr5_-_3889047 3.78 ENSDART00000185817
MLX interacting protein like
chr19_-_15177324 3.76 ENSDART00000169883
phosphatase and actin regulator 4a
chr2_+_46009507 3.75 ENSDART00000193596

chr2_+_37110504 3.75 ENSDART00000132794
ENSDART00000042974
solute carrier family 1 (glutamate transporter), member 8b
chr10_-_40964739 3.69 ENSDART00000076359
neuropeptide FF receptor 1 like 1
chr25_-_19661198 3.67 ENSDART00000149641
ATPase plasma membrane Ca2+ transporting 1b
chr12_+_4573696 3.64 ENSDART00000152534
si:dkey-94f20.4
chr1_+_57331813 3.59 ENSDART00000152440
ENSDART00000062841
epsin 3b
chr7_+_4193869 3.56 ENSDART00000138277
ENSDART00000142539
si:dkey-28d5.5
chr5_-_11971946 3.53 ENSDART00000166285
si:ch73-47f2.1
chr10_-_4980150 3.53 ENSDART00000093228
methionine adenosyltransferase II, alpha-like
chr16_-_19026414 3.52 ENSDART00000141208
Pim proto-oncogene, serine/threonine kinase, related 98
chr7_+_26100024 3.48 ENSDART00000173726
si:ch211-196f2.3
chr17_-_51224800 3.48 ENSDART00000150089
presenilin 1
chr20_-_14665002 3.45 ENSDART00000152816
secernin 2
chr18_-_21746421 3.45 ENSDART00000188809
protein serine kinase H1
chr6_+_11990733 3.41 ENSDART00000151075
bromodomain adjacent to zinc finger domain, 2Ba
chr17_-_12196865 3.39 ENSDART00000154694
kinesin family member 28
chr7_-_6417339 3.39 ENSDART00000172795
si:ch73-368j24.12
chr20_+_6543674 3.38 ENSDART00000134204
tensin 3, tandem duplicate 1
chr22_+_28995391 3.33 ENSDART00000164486
Pim proto-oncogene, serine/threonine kinase, related 99
chr3_-_2613990 3.33 ENSDART00000137102
si:dkey-217f16.6
chr23_-_10017245 3.32 ENSDART00000131669
plexin b1a
chr15_+_1137337 3.27 ENSDART00000191508
purinergic receptor P2Y13
chr15_-_43768776 3.25 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr15_+_19681718 3.21 ENSDART00000164803
si:dkey-4p15.5
chr8_-_50287949 3.20 ENSDART00000023639
NK2 transcription factor related 7
chr1_-_9109699 3.14 ENSDART00000147833
vascular associated protein
chr10_+_11265387 3.10 ENSDART00000038888
hydroxysteroid dehydrogenase like 2
chr2_+_7818368 3.08 ENSDART00000007068
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_-_29120515 3.08 ENSDART00000162016
ENSDART00000149140
zona pellucida-like domain containing 1a
chr17_-_24364527 3.07 ENSDART00000155192
WD repeat containing planar cell polarity effector
chr3_-_18792492 3.04 ENSDART00000134208
ENSDART00000034373
hydroxyacylglutathione hydrolase
chr16_-_40727455 3.02 ENSDART00000162331
si:dkey-22o22.2
chr8_+_20679759 2.99 ENSDART00000088668
nuclear factor I/C
chr23_+_16469530 2.98 ENSDART00000132898
neurotensin receptor 1 (high affinity)
chr5_-_71838520 2.86 ENSDART00000174396

chr8_-_13454281 2.84 ENSDART00000141959

chr2_-_27774783 2.83 ENSDART00000161864
zgc:123035
chr14_+_46216703 2.82 ENSDART00000136045
ENSDART00000142317
microsomal glutathione S-transferase 2
chr11_+_3578543 2.80 ENSDART00000191015
si:dkey-33m11.8
chr25_-_16826219 2.80 ENSDART00000191299
ENSDART00000188504
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr9_+_27379193 2.78 ENSDART00000142656
toll-like receptor 20, tandem duplicate 4
chr13_-_9119867 2.73 ENSDART00000137255
si:dkey-112g5.15
chr11_+_26403873 2.68 ENSDART00000109298
fer-1-like family member 4
chr17_+_51224421 2.64 ENSDART00000025229
acireductone dioxygenase 1
chr9_+_27371240 2.63 ENSDART00000060337
toll-like receptor 20, tandem duplicate 3
chr15_+_24644251 2.62 ENSDART00000181660
smoothelin, like
chr19_+_17642356 2.62 ENSDART00000176431

chr14_+_6159162 2.61 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr7_-_3657284 2.59 ENSDART00000142591
si:ch211-282j17.3
chr18_-_6862738 2.58 ENSDART00000192592

chr8_-_13486258 2.58 ENSDART00000137459
Pim proto-oncogene, serine/threonine kinase, related 104
chr15_+_19682013 2.58 ENSDART00000127368
si:dkey-4p15.5
chr2_-_25553607 2.56 ENSDART00000150075
ENSDART00000078695
growth hormone secretagogue receptor a
chr20_-_14259032 2.55 ENSDART00000169482
discs, large (Drosophila) homolog-associated protein 2b
chr21_+_43702016 2.54 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr5_+_13243446 2.52 ENSDART00000186140

chr20_+_192170 2.51 ENSDART00000189675
connexin 28.8
chr12_+_33433882 2.51 ENSDART00000185053
fatty acid synthase
chr6_+_27418541 2.49 ENSDART00000187410
ciliary rootlet coiled-coil, rootletin family member 2
chr8_-_13442871 2.48 ENSDART00000144887
Pim proto-oncogene, serine/threonine kinase, related 106
chr11_-_20956309 2.47 ENSDART00000188659

chr16_+_6021908 2.46 ENSDART00000163786

chr13_-_37254777 2.46 ENSDART00000139734
spectrin repeat containing, nuclear envelope 2b
chr18_-_16791331 2.44 ENSDART00000148222
adenosine monophosphate deaminase 3b
chr7_-_58729894 2.41 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7

Network of associatons between targets according to the STRING database.

First level regulatory network of rarga

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 28.8 GO:0098543 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
5.1 25.4 GO:0006642 triglyceride mobilization(GO:0006642)
4.8 14.3 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
4.5 31.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
3.0 12.1 GO:0070166 enamel mineralization(GO:0070166)
2.8 27.7 GO:0072337 modified amino acid transport(GO:0072337)
2.6 10.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.5 29.5 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
1.7 23.8 GO:0016556 mRNA modification(GO:0016556)
1.6 9.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
1.5 4.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.4 22.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.3 5.2 GO:0030091 protein repair(GO:0030091)
1.3 32.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.2 7.3 GO:0035889 otolith tethering(GO:0035889)
1.1 4.6 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
1.1 5.7 GO:0045056 transcytosis(GO:0045056)
1.1 9.1 GO:0031643 positive regulation of myelination(GO:0031643)
1.1 3.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.0 22.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
1.0 3.0 GO:0006089 lactate metabolic process(GO:0006089)
1.0 7.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.9 5.6 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.9 45.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.9 29.8 GO:0050821 protein stabilization(GO:0050821)
0.8 8.3 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.8 13.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 5.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.7 56.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.7 5.9 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.6 5.6 GO:0009109 coenzyme catabolic process(GO:0009109)
0.6 5.9 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.6 2.8 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.5 3.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.5 2.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.5 2.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.5 3.1 GO:0005513 detection of calcium ion(GO:0005513)
0.5 8.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 4.0 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.5 3.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 2.3 GO:0043029 T cell homeostasis(GO:0043029)
0.4 1.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 2.2 GO:0035461 vitamin transmembrane transport(GO:0035461) vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.4 2.6 GO:0034389 lipid particle organization(GO:0034389)
0.4 2.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.4 1.7 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.4 2.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 6.7 GO:0097324 melanocyte migration(GO:0097324)
0.4 1.5 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.4 10.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.4 6.8 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.3 6.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.3 5.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 9.8 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 1.9 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 1.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.3 3.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 3.2 GO:0003207 cardiac chamber formation(GO:0003207)
0.2 0.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.2 4.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 15.5 GO:0006414 translational elongation(GO:0006414)
0.2 2.1 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.6 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 2.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 10.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.2 9.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 3.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 3.4 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.4 GO:0032264 IMP salvage(GO:0032264)
0.2 3.3 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 23.8 GO:0042742 defense response to bacterium(GO:0042742)
0.1 2.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 3.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 4.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 6.6 GO:0039021 pronephric glomerulus development(GO:0039021)
0.1 1.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 5.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 1.3 GO:0050936 xanthophore differentiation(GO:0050936)
0.1 16.2 GO:0007626 locomotory behavior(GO:0007626)
0.1 2.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.6 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 4.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 2.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 9.3 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 0.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.9 GO:0044805 late nucleophagy(GO:0044805)
0.1 7.5 GO:0007605 sensory perception of sound(GO:0007605)
0.1 29.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 9.1 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.4 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 3.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 6.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 5.7 GO:0033339 pectoral fin development(GO:0033339)
0.1 5.9 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 3.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 3.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 2.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 4.7 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:0030324 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 6.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 3.1 GO:0044782 cilium organization(GO:0044782)
0.0 4.8 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.0 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 2.1 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 4.8 GO:0006412 translation(GO:0006412)
0.0 6.3 GO:0016567 protein ubiquitination(GO:0016567)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 26.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
5.1 25.4 GO:0034359 mature chylomicron(GO:0034359)
2.2 15.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.5 7.3 GO:0030314 junctional membrane complex(GO:0030314)
1.0 3.1 GO:0097541 axonemal basal plate(GO:0097541)
0.9 15.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.6 2.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.6 4.0 GO:0035253 ciliary rootlet(GO:0035253)
0.4 20.5 GO:0031941 filamentous actin(GO:0031941)
0.4 6.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 4.2 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.4 1.8 GO:1990923 PET complex(GO:1990923)
0.3 8.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 1.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 27.2 GO:0016324 apical plasma membrane(GO:0016324)
0.2 5.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 3.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 10.4 GO:0030018 Z disc(GO:0030018)
0.1 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 5.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 13.9 GO:0016459 myosin complex(GO:0016459)
0.1 5.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 9.6 GO:0005882 intermediate filament(GO:0005882)
0.1 3.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 4.3 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 164.8 GO:0005576 extracellular region(GO:0005576)
0.1 4.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 5.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 2.1 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 4.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.0 3.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 6.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.9 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 4.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.4 GO:0000786 nucleosome(GO:0000786)
0.0 3.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 5.8 GO:0005911 cell-cell junction(GO:0005911)
0.0 4.9 GO:0000785 chromatin(GO:0000785)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 21.4 GO:0005829 cytosol(GO:0005829)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 8.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 28.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
7.5 29.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
6.2 31.2 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
5.5 27.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
5.3 21.3 GO:0070324 thyroid hormone binding(GO:0070324)
3.4 23.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
3.3 29.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.9 14.3 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
2.8 25.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
2.6 10.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.4 26.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.0 8.1 GO:0008887 glycerate kinase activity(GO:0008887)
1.9 9.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.8 22.9 GO:0016405 CoA-ligase activity(GO:0016405)
1.6 6.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.3 5.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
1.2 13.2 GO:0035804 structural constituent of egg coat(GO:0035804)
1.0 20.5 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
1.0 7.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 3.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.8 22.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.8 8.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.8 9.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 15.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.7 18.1 GO:0005112 Notch binding(GO:0005112)
0.7 2.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.7 45.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.7 3.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.5 3.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.5 6.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.5 4.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.5 3.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 4.9 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.5 54.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 3.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.5 1.8 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.4 4.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 10.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.4 2.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 15.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.2 GO:0034632 retinol transporter activity(GO:0034632)
0.3 21.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 4.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 5.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 4.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 6.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 1.8 GO:0034584 piRNA binding(GO:0034584)
0.2 9.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 2.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 11.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 6.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 7.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.2 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 17.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 5.7 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 2.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 8.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 2.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 1.6 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 1.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 8.1 GO:0003823 antigen binding(GO:0003823)
0.1 1.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 3.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 3.0 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 6.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 6.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 2.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 7.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 18.0 GO:0003774 motor activity(GO:0003774)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 12.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0016918 retinal binding(GO:0016918)
0.1 9.9 GO:0015293 symporter activity(GO:0015293)
0.0 6.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 26.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 5.8 GO:0016853 isomerase activity(GO:0016853)
0.0 2.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 27.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 3.9 GO:0008236 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 2.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 31.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.5 21.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 61.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 7.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 3.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 5.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 14.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 5.6 PID P73PATHWAY p73 transcription factor network
0.1 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.1 22.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.9 9.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.9 21.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.6 9.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 7.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 11.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 1.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 4.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 3.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 39.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 2.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 6.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 5.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 4.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 5.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.8 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 9.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 12.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.9 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo