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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for prdm1a

Z-value: 1.67

Motif logo

Transcription factors associated with prdm1a

Gene Symbol Gene ID Gene Info
ENSDARG00000002445 PR domain containing 1a, with ZNF domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm1adr11_v1_chr16_-_7443388_74433880.777.8e-20Click!

Activity profile of prdm1a motif

Sorted Z-values of prdm1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_17776981 21.06 ENSDART00000141693
chemokine (C-C motif) ligand 19b
chr6_-_40657653 15.24 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr8_-_50259448 15.09 ENSDART00000146056
NK3 homeobox 1
chr25_+_10416583 15.06 ENSDART00000073907
ets homologous factor
chr5_+_13373593 14.73 ENSDART00000051668
ENSDART00000183883
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr6_+_46697710 11.59 ENSDART00000154969
thymocyte expressed, positive selection associated 1
chr19_+_18739085 10.98 ENSDART00000188868
sperm acrosome associated 4 like
chr4_-_76370630 10.26 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
chr6_-_39313027 9.79 ENSDART00000012644
keratin 4
chr22_+_36704764 9.67 ENSDART00000146662
tripartite motif containing 35-33
chr15_+_17752928 9.38 ENSDART00000155314
si:ch211-213d14.2
chr21_+_5636008 9.31 ENSDART00000158385
shroom family member 3
chr18_+_8812549 9.30 ENSDART00000017619
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr12_+_17042754 8.36 ENSDART00000066439
cholesterol 25-hydroxylase
chr13_+_42011287 8.32 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr15_+_24572926 8.16 ENSDART00000155636
ENSDART00000187800
dehydrogenase/reductase (SDR family) member 13b
chr22_-_36926342 8.03 ENSDART00000151804
si:dkey-37m8.11
chr16_-_9802998 7.87 ENSDART00000154217
TAP binding protein (tapasin)-like
chr11_-_18705303 7.75 ENSDART00000059732
inhibitor of DNA binding 1
chr16_-_9802449 7.71 ENSDART00000081208
TAP binding protein (tapasin)-like
chr22_+_36902352 7.63 ENSDART00000036273
tripartite motif containing 35-20
chr7_-_28148310 7.32 ENSDART00000044208
LIM domain only 1
chr17_-_31058900 7.24 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
echinoderm microtubule associated protein like 1
chr4_+_25558849 6.98 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
chr3_+_6291635 6.87 ENSDART00000185055
ENSDART00000157707
si:ch211-12p12.2
chr19_+_7115223 6.80 ENSDART00000001359
proteasome subunit beta 12
chr15_-_47929455 6.79 ENSDART00000064462
proteasome subunit alpha 6, like
chr23_-_27123171 6.53 ENSDART00000023218
ENSDART00000146467
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_-_18164671 6.41 ENSDART00000014057
regulatory factor X-associated ankyrin-containing protein
chr3_-_8035737 6.39 ENSDART00000170642
tripartite motif containing 35-19
chr14_+_21159693 6.34 ENSDART00000192678
zgc:136929
chr4_-_76206413 6.23 ENSDART00000170738
si:ch211-106j21.5
chr16_-_51271962 6.19 ENSDART00000164021
ENSDART00000046420
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr3_-_7948799 6.19 ENSDART00000163714
tripartite motif containing 35-24
chr8_+_39998467 6.13 ENSDART00000073782
ENSDART00000134452
gamma-glutamyltransferase 5a
chr19_-_7115229 6.12 ENSDART00000001930
proteasome subunit beta 13a
chr20_-_26929685 6.07 ENSDART00000132556
finTRIM family, member 79
chr5_-_57723929 6.06 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr8_-_46457233 6.01 ENSDART00000113214
sulfotransferase family 1, cytosolic sulfotransferase 7
chr7_+_65673885 5.98 ENSDART00000169182
parvin, alpha b
chr7_+_39416336 5.82 ENSDART00000171783

chr6_-_8580857 5.74 ENSDART00000138858
ENSDART00000041142
myosin, heavy chain 11a, smooth muscle
chr7_+_26167420 5.73 ENSDART00000173941
si:ch211-196f2.6
chr4_-_77216726 5.54 ENSDART00000099943
proteasome subunit beta 10
chr2_+_42005217 5.49 ENSDART00000143562
guanylate binding protein 2
chr7_+_36552725 5.43 ENSDART00000173682
chromodomain helicase DNA binding protein 9
chr24_-_20915050 5.34 ENSDART00000133763
si:ch211-161h7.5
chr3_-_3019979 5.30 ENSDART00000111174
zgc:172090
chr18_-_16953978 5.27 ENSDART00000100126
A kinase (PRKA) interacting protein 1
chr22_-_18164835 5.27 ENSDART00000143189
regulatory factor X-associated ankyrin-containing protein
chr5_+_59494079 5.18 ENSDART00000148727
GTF2I repeat domain containing 1
chr7_+_48870496 5.18 ENSDART00000009642
insulin-like growth factor 2a
chr5_-_38197080 5.10 ENSDART00000140708
si:ch211-284e13.9
chr24_+_39641991 5.03 ENSDART00000142182
LUC7-like (S. cerevisiae)
chr3_+_1942219 4.94 ENSDART00000114520
zgc:165583
chr2_-_16254782 4.91 ENSDART00000133708
Rho guanine nucleotide exchange factor (GEF) 4
chr9_-_8454060 4.79 ENSDART00000110158
insulin receptor substrate 2b
chr1_+_31942961 4.72 ENSDART00000007522
anosmin 1a
chr21_+_30306369 4.66 ENSDART00000145050
ENSDART00000059420
lymphocyte cytosolic protein 2a
chr19_+_23296616 4.57 ENSDART00000134567
immunity-related GTPase family, f1
chr8_+_39570615 4.45 ENSDART00000142557
leucine zipper, putative tumor suppressor 1
chr15_-_36347858 4.40 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
chr7_+_11197940 4.39 ENSDART00000081346
cell migration inducing protein, hyaluronan binding
chr6_+_24661736 4.37 ENSDART00000169283
zinc finger protein 644b
chr13_+_2830574 4.35 ENSDART00000138143
si:ch211-233m11.1
chr17_+_45404758 4.26 ENSDART00000147557
T cell activation RhoGTPase activating protein a
chr13_-_377256 4.25 ENSDART00000137398
ch1073-291c23.1
chr11_-_21528056 4.24 ENSDART00000181626
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_38025319 4.22 ENSDART00000155000
si:ch73-380l3.3
chr5_-_26247973 4.20 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr24_-_21713883 4.17 ENSDART00000081357
fms-related tyrosine kinase 3
chr7_-_3693303 4.16 ENSDART00000166949
si:ch211-282j17.13
chr11_-_26040594 4.15 ENSDART00000144115
kazrin, periplakin interacting protein b
chr1_-_2457546 4.10 ENSDART00000103795
gamma-glutamylamine cyclotransferase, tandem duplicate 1
chr5_-_26247671 4.05 ENSDART00000145187
endoplasmic reticulum aminopeptidase 1b
chr1_+_58360935 4.04 ENSDART00000140754
si:dkey-222h21.1
chr1_-_31083535 3.99 ENSDART00000138113
protein phosphatase 1 regulatory subunit 9A-like B
chr3_+_24618012 3.94 ENSDART00000111997
zgc:171506
chr4_-_76129431 3.92 ENSDART00000162809
si:ch211-106j21.2
chr20_-_4793450 3.82 ENSDART00000053870
galactosylceramidase a
chr14_+_45566074 3.81 ENSDART00000133477
ENSDART00000185899
zgc:92249
chr18_-_18543358 3.72 ENSDART00000126460
interleukin 34
chr22_+_36719821 3.71 ENSDART00000149093
si:ch1073-324l1.1
chr20_-_20402500 3.53 ENSDART00000190747
ENSDART00000185065
protein kinase C, eta, b
chr4_-_76239517 3.52 ENSDART00000172599
si:ch211-106j21.6
chr20_-_25412181 3.46 ENSDART00000062780
intersectin 2a
chr4_+_38550788 3.46 ENSDART00000157412
si:ch211-209n20.1
chr25_+_8955530 3.45 ENSDART00000156444
si:ch211-256a21.4
chr14_-_1543834 3.42 ENSDART00000185876

chr24_-_39610585 3.39 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr25_+_4979446 3.35 ENSDART00000154131
ENSDART00000155537
si:ch73-265h17.1
chr10_-_45230081 3.35 ENSDART00000169845
poly (ADP-ribose) glycohydrolase, like
chr6_-_1587291 3.30 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr19_-_10971230 3.30 ENSDART00000166196

chr7_-_37563883 3.30 ENSDART00000148805
nucleotide-binding oligomerization domain containing 2
chr16_-_41488023 3.29 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr20_-_6196989 3.25 ENSDART00000013343
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr5_-_43935460 3.23 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
chr19_+_23298037 3.20 ENSDART00000183948
immunity-related GTPase family, f1
chr18_+_14684115 3.11 ENSDART00000108469
spermatogenesis associated 2-like
chr12_-_2869565 3.05 ENSDART00000152772
zinc finger, DHHC-type containing 16b
chr2_+_42005475 3.05 ENSDART00000056461
guanylate binding protein 2
chr4_-_75616197 3.01 ENSDART00000157778
si:dkey-71l4.3
chr23_+_642001 2.96 ENSDART00000030643
ENSDART00000124850
interferon regulatory factor 10
chr4_-_76027176 2.93 ENSDART00000165718
si:dkey-71l4.1
chr10_-_34981028 2.93 ENSDART00000186108
SMAD family member 9
chr7_-_3669868 2.91 ENSDART00000172907
si:ch211-282j17.12
chr5_+_22406672 2.87 ENSDART00000141385
si:dkey-27p18.3
chr1_-_8966046 2.86 ENSDART00000136198
suppressor of cytokine signaling 1b
chr4_-_60916298 2.84 ENSDART00000142335
si:dkey-196n19.2
chr7_+_49695904 2.83 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr1_+_40034061 2.80 ENSDART00000011727
coiled-coil domain containing 149b
chr23_+_24705424 2.72 ENSDART00000104029
C1q and TNF related 12
chr20_-_26936887 2.66 ENSDART00000160827
finTRIM family, member 79
chr24_+_26402110 2.59 ENSDART00000133684
si:ch211-230g15.5
chr13_-_24429066 2.58 ENSDART00000147514
ENSDART00000057588
centrosomal protein 68
chr7_-_32782430 2.57 ENSDART00000173808
growth arrest-specific 2b
chr4_-_70057031 2.53 ENSDART00000158207
ENSDART00000184786
ENSDART00000182391
ENSDART00000167979
si:ch211-171l17.14
chr7_-_3693536 2.53 ENSDART00000126381
si:ch211-282j17.13
chr5_-_44286987 2.52 ENSDART00000184112
si:ch73-337l15.2
chr3_+_59935606 2.52 ENSDART00000154157
Rho GDP dissociation inhibitor (GDI) alpha
chr17_+_1063988 2.51 ENSDART00000160400
GTP cyclohydrolase I feedback regulator
chr17_-_29902187 2.51 ENSDART00000009104
estrogen-related receptor beta
chr9_+_23765587 2.49 ENSDART00000145120
si:ch211-219a4.3
chr10_-_34981219 2.46 ENSDART00000132823
SMAD family member 9
chr3_+_39663987 2.44 ENSDART00000184614
ENSDART00000184573
ENSDART00000183127
epsin 2
chr7_+_60111581 2.43 ENSDART00000087093
heat shock protein 12B
chr3_+_32833661 2.40 ENSDART00000183878
CD2 (cytoplasmic tail) binding protein 2
chr17_-_11439815 2.38 ENSDART00000130105
proteasome subunit alpha 3
chr3_-_7997887 2.34 ENSDART00000172256
si:ch211-175l6.2
chr13_+_11550454 2.31 ENSDART00000034935
ENSDART00000166908
desumoylating isopeptidase 2
chr23_+_642395 2.28 ENSDART00000186995
interferon regulatory factor 10
chr5_-_64454459 2.27 ENSDART00000172321
ENSDART00000168030
bromodomain containing 3b
chr4_+_17524330 2.26 ENSDART00000172169
ENSDART00000021610
RecQ helicase-like
chr2_+_30969029 2.24 ENSDART00000085242
lipin 2
chr16_-_25535430 2.19 ENSDART00000077420
dystrobrevin binding protein 1a
chr4_-_75511162 2.17 ENSDART00000157651
si:dkey-71l4.5
chr1_-_45636362 2.15 ENSDART00000181757
septin 3
chr1_-_44710937 2.12 ENSDART00000139036
si:dkey-28b4.7
chr10_+_9222476 2.10 ENSDART00000064973
ENSDART00000145879
progestin and adipoQ receptor family member IIIb
chr14_-_4120636 2.06 ENSDART00000059230
interferon regulatory factor 2
chr3_+_12593558 2.04 ENSDART00000186891
ENSDART00000159252
ATP-binding cassette, sub-family A (ABC1), member 3b
chr19_+_9032073 2.02 ENSDART00000127755
ash1 (absent, small, or homeotic)-like (Drosophila)
chr13_-_50234122 2.02 ENSDART00000164338
eukaryotic translation initiation factor 2-alpha kinase 2
chr4_-_75641117 1.99 ENSDART00000182165
si:dkey-71l4.2
chr6_+_38896158 1.98 ENSDART00000029930
ENSDART00000131347
solute carrier family 48 (heme transporter), member 1b
chr6_-_19271210 1.98 ENSDART00000163628
ENSDART00000159124
zgc:174863
chr14_-_4121052 1.97 ENSDART00000167074
interferon regulatory factor 2
chr19_-_6774871 1.96 ENSDART00000170952
poliovirus receptor-related 2 like
chr25_+_245018 1.96 ENSDART00000155344
zgc:92481
chr19_+_8612839 1.93 ENSDART00000144925
sorting nexin family member 27a
chr3_-_22366562 1.91 ENSDART00000129447
interferon phi 1
chr18_-_12858016 1.91 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr1_-_19599242 1.89 ENSDART00000088949
si:dkey-245p14.7
chr5_-_26247215 1.87 ENSDART00000136806
endoplasmic reticulum aminopeptidase 1b
chr8_-_27858458 1.87 ENSDART00000132632
ENSDART00000136562
CTTNBP2 N-terminal like b
chr23_-_33709964 1.83 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr3_-_10739625 1.80 ENSDART00000156144
zgc:112965
chr4_-_20208166 1.78 ENSDART00000066891
gamma-secretase activating protein
chr19_+_14115838 1.76 ENSDART00000192057
keratinocyte differentiation factor 1b
chr4_-_71177920 1.71 ENSDART00000158287
si:dkey-193i10.1
chr4_+_70791887 1.70 ENSDART00000164234
si:ch211-127b6.2
chr4_+_70911498 1.70 ENSDART00000157674
si:dkey-16p6.1
chr4_+_5132951 1.68 ENSDART00000103279
cyclin D2, b
chr5_-_43935119 1.68 ENSDART00000142271
si:ch211-204c21.1
chr3_-_22366032 1.67 ENSDART00000029849
interferon phi 1
chr23_+_2825940 1.66 ENSDART00000135781
phospholipase C, gamma 1
chr4_-_75615597 1.66 ENSDART00000187794
si:dkey-71l4.3
chr3_-_1859198 1.65 ENSDART00000121870
MICAL like 1b, duplicate 2
chr3_-_34586403 1.63 ENSDART00000151515
septin 9a
chr10_+_28587446 1.61 ENSDART00000030138
ENSDART00000137508
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr21_+_20356458 1.59 ENSDART00000135816
phosphodiesterase 6B, cGMP-specific, rod, beta
chr5_+_21211135 1.57 ENSDART00000088492
bone morphogenetic protein 10
chr3_-_367283 1.56 ENSDART00000155936
ENSDART00000161964
ENSDART00000158560
ENSDART00000135595
ENSDART00000145890
major histocompatibility complex class I ZAA
chr4_-_22338906 1.51 ENSDART00000131402
golgin B1
chr24_+_38216340 1.50 ENSDART00000188561

chr3_-_7961226 1.48 ENSDART00000159801
tripartite motif containing 35-23
chr1_+_57787642 1.48 ENSDART00000127091
si:dkey-1c7.2
chr23_-_37835794 1.47 ENSDART00000137358
CD40 molecule, TNF receptor superfamily member 5
chr9_-_15208129 1.46 ENSDART00000137043
ENSDART00000131512
par-3 family cell polarity regulator beta b
chr8_-_25690966 1.46 ENSDART00000033701
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ga
chr14_-_25078569 1.46 ENSDART00000172802
ENSDART00000173345
ENSDART00000135004
matrin 3-like 1.1
chr3_+_47322494 1.45 ENSDART00000102202
phosphatidic acid phosphatase type 2D
chr10_-_45229877 1.40 ENSDART00000169281
poly (ADP-ribose) glycohydrolase, like
chr14_-_25444774 1.39 ENSDART00000183448
solute carrier family 26 (anion exchanger), member 2
chr23_-_6982966 1.37 ENSDART00000033774
ENSDART00000169965
ER degradation enhancer, mannosidase alpha-like 2
chr3_-_7974028 1.34 ENSDART00000144459
tripartite motif containing 35-22
chr20_+_715739 1.33 ENSDART00000136768
myosin VIa
chr18_-_37252036 1.29 ENSDART00000132230
SIX homeobox 5
chr23_+_33718602 1.23 ENSDART00000024695
DAZ associated protein 2
chr13_-_43637371 1.22 ENSDART00000127930
ENSDART00000084474
family with sequence similarity 160, member B1
chr1_-_54938137 1.20 ENSDART00000147212
cartilage acidic protein 1a
chr22_+_1440702 1.19 ENSDART00000165677
si:dkeyp-53d3.3
chr1_+_57774454 1.18 ENSDART00000152507
si:dkey-1c7.2
chr19_+_42716542 1.16 ENSDART00000144557
cytoplasmic linker associated protein 2
chr3_-_31833266 1.11 ENSDART00000084932
ENSDART00000183617
mitogen-activated protein kinase kinase kinase 3
chr24_+_12945803 1.11 ENSDART00000005105
proteasome activator subunit 1
chr4_+_29702703 1.10 ENSDART00000167771
si:ch211-214c20.1
chr4_+_70967639 1.08 ENSDART00000159230
si:dkeyp-80d11.12
chr3_-_5393909 1.08 ENSDART00000031885
si:ch73-106l15.2

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
2.3 25.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.2 3.7 GO:0045649 regulation of macrophage differentiation(GO:0045649)
1.2 6.1 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
1.1 6.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
1.0 44.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
1.0 7.6 GO:0034341 response to interferon-gamma(GO:0034341)
0.9 9.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.8 4.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.7 23.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.7 2.7 GO:0046324 regulation of glucose import(GO:0046324)
0.7 7.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.6 8.3 GO:0042572 retinol metabolic process(GO:0042572)
0.6 5.7 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.6 1.7 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.5 2.2 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.5 15.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 3.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.4 3.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.4 11.0 GO:0007286 spermatid development(GO:0007286)
0.4 4.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.4 5.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.4 1.5 GO:0051660 establishment of centrosome localization(GO:0051660)
0.4 9.3 GO:0001843 neural tube closure(GO:0001843)
0.4 1.8 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 5.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.3 0.9 GO:0035046 pronuclear migration(GO:0035046)
0.3 4.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.3 1.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.3 4.9 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.3 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 4.2 GO:0030225 macrophage differentiation(GO:0030225)
0.2 6.0 GO:0051923 sulfation(GO:0051923)
0.2 0.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.2 1.0 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 4.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 2.0 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 1.8 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.2 7.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 5.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.2 4.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.2 2.6 GO:0051764 actin crosslink formation(GO:0051764)
0.2 4.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 6.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 5.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 11.9 GO:0050673 epithelial cell proliferation(GO:0050673)
0.1 3.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 4.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 4.7 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.1 0.4 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 1.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 3.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.5 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 6.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 48.0 GO:0016567 protein ubiquitination(GO:0016567)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 5.4 GO:0061515 myeloid cell development(GO:0061515)
0.1 1.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.1 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 3.1 GO:0018345 protein palmitoylation(GO:0018345)
0.1 2.8 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 1.4 GO:0008272 sulfate transport(GO:0008272) otolith morphogenesis(GO:0032474)
0.0 4.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 1.6 GO:0060840 artery development(GO:0060840)
0.0 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 4.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 1.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.0 GO:0030261 chromosome condensation(GO:0030261)
0.0 4.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.7 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.1 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 2.3 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 2.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 2.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.0 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 4.0 GO:0032259 methylation(GO:0032259)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0042148 strand invasion(GO:0042148)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.8 GO:0045095 keratin filament(GO:0045095)
0.8 23.8 GO:0005839 proteasome core complex(GO:0005839)
0.4 2.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 2.4 GO:0005682 U5 snRNP(GO:0005682)
0.3 1.1 GO:0008537 proteasome activator complex(GO:0008537)
0.3 2.0 GO:0016586 RSC complex(GO:0016586)
0.2 1.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 5.0 GO:0005685 U1 snRNP(GO:0005685)
0.2 9.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 4.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 2.4 GO:0030666 clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 2.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.0 GO:0000938 GARP complex(GO:0000938)
0.1 4.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 9.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 2.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.0 GO:0035101 FACT complex(GO:0035101)
0.1 4.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 3.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 5.7 GO:0016459 myosin complex(GO:0016459)
0.0 9.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 29.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 47.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 2.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 11.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 5.8 GO:0005764 lysosome(GO:0005764)
0.0 8.2 GO:0000785 chromatin(GO:0000785)
0.0 2.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.8 GO:0009986 cell surface(GO:0009986)
0.0 5.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 1.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 63.0 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.4 8.3 GO:0070330 aromatase activity(GO:0070330)
1.2 8.4 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
1.2 3.6 GO:0005132 type I interferon receptor binding(GO:0005132)
1.2 4.7 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
1.1 3.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.9 17.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 35.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.8 2.3 GO:0036310 annealing helicase activity(GO:0036310)
0.7 6.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.7 6.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.6 5.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 1.6 GO:0047690 aspartyltransferase activity(GO:0047690)
0.5 2.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4 4.8 GO:0005158 insulin receptor binding(GO:0005158)
0.4 11.0 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.3 3.3 GO:0050700 CARD domain binding(GO:0050700)
0.3 10.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 15.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 2.0 GO:0015232 heme transporter activity(GO:0015232)
0.2 7.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 4.2 GO:0031267 small GTPase binding(GO:0031267)
0.2 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 8.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 5.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 3.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 39.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 6.3 GO:0051287 NAD binding(GO:0051287)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 10.9 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 34.3 GO:0005525 GTP binding(GO:0005525)
0.1 19.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 7.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.2 GO:0019199 transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0 1.6 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 12.2 GO:0008017 microtubule binding(GO:0008017)
0.0 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 2.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 10.1 GO:0046983 protein dimerization activity(GO:0046983)
0.0 4.2 GO:0016829 lyase activity(GO:0016829)
0.0 2.0 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.6 GO:0060090 binding, bridging(GO:0060090)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 4.2 GO:0003779 actin binding(GO:0003779)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.9 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.1 PID ALK1 PATHWAY ALK1 signaling events
0.4 12.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 11.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 6.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 1.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 4.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.4 PID AURORA B PATHWAY Aurora B signaling
0.1 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.9 8.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 12.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.4 1.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 2.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 4.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 2.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 1.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 3.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 5.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 6.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides