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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pou4f3_pou4f1+pou4f4

Z-value: 2.75

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Transcription factors associated with pou4f3_pou4f1+pou4f4

Gene Symbol Gene ID Gene Info
ENSDARG00000006206 POU class 4 homeobox 3
ENSDARG00000005559 POU class 4 homeobox 1
ENSDARG00000044375 zgc
ENSDARG00000111929 zgc

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f1dr11_v1_chr6_+_4539953_45399530.931.7e-40Click!
zgc:158291dr11_v1_chr21_+_38312549_383125490.911.1e-36Click!
pou4f3dr11_v1_chr9_+_54290896_542908960.122.5e-01Click!

Activity profile of pou4f3_pou4f1+pou4f4 motif

Sorted Z-values of pou4f3_pou4f1+pou4f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_21688176 76.22 ENSDART00000063825
shadow of prion protein
chr23_-_27345425 59.43 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr20_+_9355912 48.65 ENSDART00000142337
si:dkey-174m14.3
chr4_+_12111154 48.06 ENSDART00000036779
transmembrane protein 178B
chr16_-_12953739 47.72 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr24_+_14713776 46.20 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr23_-_29376859 44.31 ENSDART00000146411
somatostatin 6
chr23_-_24195519 42.56 ENSDART00000112370
ENSDART00000180377
anoctamin 11
chr24_-_3419998 42.50 ENSDART00000066839
solute carrier family 35, member G2b
chr16_+_10318893 40.74 ENSDART00000055380
tubulin, beta 5
chr5_+_58372164 39.29 ENSDART00000057910
neurogranin (protein kinase C substrate, RC3) a
chr2_+_50608099 38.80 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr11_+_6819050 37.83 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr23_-_24195723 36.54 ENSDART00000145489
anoctamin 11
chr2_+_39108339 36.53 ENSDART00000085675
calsyntenin 2
chr13_-_43599898 35.57 ENSDART00000084416
ENSDART00000145705
actin binding LIM protein 1a
chr16_+_14029283 34.71 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr21_-_13123176 34.05 ENSDART00000144866
ENSDART00000024616
family with sequence similarity 219, member Aa
chr9_-_6661657 34.02 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
POU class 3 homeobox 3a
chr20_-_34801181 33.75 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr16_+_10776688 32.58 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr9_-_18735256 31.03 ENSDART00000143165
TSC22 domain family, member 1
chr14_-_18672561 30.38 ENSDART00000166730
ENSDART00000006998
SLIT and NTRK-like family, member 4
chr25_-_4148719 30.28 ENSDART00000112880
ENSDART00000023278
fatty acid desaturase 2
chr12_-_10705916 28.90 ENSDART00000164038

chr11_+_37137196 28.17 ENSDART00000172950
WNK lysine deficient protein kinase 2
chr2_+_25929619 28.11 ENSDART00000137746
solute carrier family 7, member 14a
chr20_+_22045089 27.55 ENSDART00000063564
ENSDART00000187013
ENSDART00000161552
ENSDART00000174478
ENSDART00000063568
ENSDART00000152247
neuromedin U
chr5_-_31689796 27.47 ENSDART00000184319
ENSDART00000190229
ENSDART00000186294
ENSDART00000170313
ENSDART00000147065
ENSDART00000134427
ENSDART00000098172
SH3-domain GRB2-like endophilin B2b
chr21_+_26389391 27.29 ENSDART00000077197
thymosin, beta
chr6_-_39489190 27.09 ENSDART00000151299
sodium channel, voltage gated, type VIII, alpha subunit b
chr5_-_30418636 25.96 ENSDART00000098285
activating transcription factor 5a
chr1_-_22861348 25.64 ENSDART00000139412
si:dkey-92j12.6
chr4_+_9669717 24.57 ENSDART00000004604
si:dkey-153k10.9
chr22_-_28226948 24.16 ENSDART00000147686
si:dkey-222p3.1
chr6_-_35446110 23.81 ENSDART00000058773
regulator of G protein signaling 16
chr7_-_28148310 23.24 ENSDART00000044208
LIM domain only 1
chr20_-_31808779 22.42 ENSDART00000133788
syntaxin binding protein 5a (tomosyn)
chr6_-_41229787 21.78 ENSDART00000065013
synaptoporin
chr19_+_30662529 21.78 ENSDART00000175662
family with sequence similarity 49, member A-like
chr5_-_23429228 21.30 ENSDART00000049291
glutamate receptor, ionotropic, AMPA 3a
chr9_+_34319333 20.63 ENSDART00000035522
ENSDART00000146480
POU class 2 homeobox 1b
chr5_+_4054704 19.84 ENSDART00000140537
dehydrogenase/reductase (SDR family) member 11a
chr1_+_31113951 19.40 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1b
chr25_+_24291156 18.69 ENSDART00000083407
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr15_+_24704798 17.98 ENSDART00000192470
si:dkey-151p21.7
chr11_+_23957440 17.83 ENSDART00000190721
contactin 2
chr20_+_27298783 17.34 ENSDART00000013861
protein phosphatase 4, regulatory subunit 4
chr25_-_13614863 17.23 ENSDART00000121859
fatty acid 2-hydroxylase
chr20_+_37661547 16.63 ENSDART00000007253
androgen-induced 1 (H. sapiens)
chr11_-_38083397 16.50 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr3_+_22578369 16.01 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr11_+_30057762 15.95 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr9_+_7030016 15.88 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr2_-_30784198 15.69 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr20_+_20638034 15.21 ENSDART00000189759
reticulon 1b
chr11_+_25101220 15.06 ENSDART00000183700
ndrg family member 3a
chr9_+_11034314 15.00 ENSDART00000032695
acid-sensing (proton-gated) ion channel family member 4a
chr17_-_51893123 14.95 ENSDART00000103350
ENSDART00000017329
numb homolog (Drosophila)
chr20_-_44575103 14.61 ENSDART00000192573
UBX domain protein 2A
chr3_+_33440615 14.44 ENSDART00000146005
GTP binding protein 1
chr1_+_38758445 14.34 ENSDART00000136300
WD repeat domain 17
chr22_-_3564563 14.34 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr1_+_38758261 14.22 ENSDART00000182756
WD repeat domain 17
chr2_+_22702488 14.11 ENSDART00000076647
kinesin family member 1Ab
chr10_+_38775408 14.04 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr13_+_27951688 14.04 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr21_-_39177564 13.98 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr20_+_31076488 13.87 ENSDART00000136255
ENSDART00000008840
otoferlin a
chr17_+_33999630 13.85 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gephyrin a
chr20_+_41756996 13.60 ENSDART00000186393
family with sequence similarity 184, member A
chr23_+_6232895 13.53 ENSDART00000139795
synaptotagmin IIa
chr13_+_23282549 13.51 ENSDART00000101134
KH domain containing, RNA binding, signal transduction associated 2
chr1_-_21901589 13.46 ENSDART00000140553
FERM and PDZ domain containing 1a
chr15_+_32297441 13.25 ENSDART00000153657
tripartite motif containing 3a
chr13_+_8604710 13.18 ENSDART00000091097
suppressor of cytokine signaling 5b
chr12_+_2446837 13.18 ENSDART00000112032
si:dkey-191m6.4
chr9_+_44430705 13.02 ENSDART00000190696
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr16_-_31351419 12.86 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr11_+_23760470 12.48 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr1_-_15797663 12.44 ENSDART00000177122
sarcoglycan zeta
chr13_+_12299997 12.31 ENSDART00000108535
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr20_+_17783404 12.25 ENSDART00000181946
cadherin 2, type 1, N-cadherin (neuronal)
chr23_-_30431333 11.96 ENSDART00000146633
calmodulin binding transcription activator 1a
chr13_+_36622100 11.72 ENSDART00000133198
si:ch211-67f24.7
chr16_+_29630965 11.50 ENSDART00000185820
ENSDART00000192105
ENSDART00000153683
ENSDART00000186713
si:ch211-203d17.1
chr3_-_28048475 11.32 ENSDART00000150888
RNA binding fox-1 homolog 1
chr3_-_28665291 11.24 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr19_-_43552252 11.21 ENSDART00000138308
G protein-coupled receptor 186
chr6_-_16394528 11.18 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr6_-_6423885 11.11 ENSDART00000092257
si:ch211-194e18.2
chr13_-_39830999 10.98 ENSDART00000115089
zgc:171482
chr20_-_10120442 10.69 ENSDART00000144970
Meis homeobox 2b
chr17_-_8673278 10.63 ENSDART00000171850
ENSDART00000017337
ENSDART00000148504
ENSDART00000148808
C-terminal binding protein 2a
chr6_+_38427570 10.55 ENSDART00000170612
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_43401005 10.34 ENSDART00000110994
squalene epoxidase a
chr25_+_21833287 10.30 ENSDART00000187606
creatine kinase, mitochondrial 1
chr1_+_25783801 10.26 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr23_+_21479958 10.18 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
chr24_-_26622423 9.88 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr7_+_7019911 9.84 ENSDART00000172421
RNA binding motif protein 14b
chr1_+_22851261 9.83 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr17_+_26208630 9.63 ENSDART00000087084
glutamate receptor, ionotropic, delta 1a
chr2_-_24348948 9.52 ENSDART00000136559
anoctamin 8a
chr17_-_8673567 9.30 ENSDART00000192714
ENSDART00000012546
C-terminal binding protein 2a
chr17_+_15983247 9.25 ENSDART00000154275
calmin
chr10_-_29892486 9.20 ENSDART00000099983
brain-specific homeobox
chr3_-_23407720 9.18 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr15_-_14552101 9.08 ENSDART00000171169
numb homolog (Drosophila)-like
chr17_+_9009098 9.07 ENSDART00000180856
A kinase (PRKA) anchor protein 6
chr2_-_22286828 9.05 ENSDART00000168653
family with sequence similarity 110, member B
chr17_-_20287530 8.87 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr20_-_11178022 8.71 ENSDART00000152246
fibronectin leucine rich transmembrane protein 2
chr14_+_36231126 8.61 ENSDART00000141766
ELOVL fatty acid elongase 6
chr2_-_24348642 8.51 ENSDART00000181739
anoctamin 8a
chr22_+_15507218 8.43 ENSDART00000125450
glypican 1a
chr23_-_27692717 8.34 ENSDART00000053878
ENSDART00000145028
si:dkey-166n8.9
chr18_+_34362608 8.18 ENSDART00000131478
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr5_-_41103583 8.05 ENSDART00000051070
ENSDART00000074781
golgi phosphoprotein 3
chr12_-_19151708 8.00 ENSDART00000057124
thyrotrophic embryonic factor a
chr14_-_47849216 8.00 ENSDART00000192796
Rap guanine nucleotide exchange factor (GEF) 2
chr22_-_29906764 7.84 ENSDART00000019786
structural maintenance of chromosomes 3
chr1_-_22851481 7.78 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr7_-_25895189 7.77 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr13_-_16066997 7.61 ENSDART00000184790
spermatogenesis associated 48
chr2_+_32846602 7.60 ENSDART00000056649
transmembrane protein 53
chr3_-_16055432 7.59 ENSDART00000123621
ENSDART00000023859
ATPase H+ transporting V0 subunit ca
chr19_+_42693855 7.59 ENSDART00000136873
cytoplasmic linker associated protein 2
chr20_-_39103119 7.19 ENSDART00000143379
regulator of calcineurin 2
chr4_+_21867522 7.12 ENSDART00000140400
acyl-CoA synthetase short chain family member 3
chr23_+_23658474 7.00 ENSDART00000162838
agrin
chr2_-_3045861 6.94 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr10_+_39084354 6.68 ENSDART00000158245
si:ch73-1a9.3
chr13_+_27298673 6.61 ENSDART00000142922
solute carrier family 17 (acidic sugar transporter), member 5
chr22_+_11153590 6.61 ENSDART00000188207
BCL6 corepressor
chr18_-_23875370 6.46 ENSDART00000130163
nuclear receptor subfamily 2, group F, member 2
chr16_+_1353894 6.36 ENSDART00000148426
cugbp, Elav-like family member 3b
chr8_+_7975745 6.31 ENSDART00000137920
si:ch211-169p10.1
chr24_+_3328354 6.25 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr23_+_19977120 6.23 ENSDART00000089342
cilia and flagella associated protein 126
chr14_-_39031108 6.10 ENSDART00000026194
glycine receptor, alpha 4a
chr8_+_30600386 6.09 ENSDART00000164976
sperm antigen with calponin homology and coiled-coil domains 1-like a
chr1_-_44581937 6.09 ENSDART00000009858
thioredoxin-related transmembrane protein 2b
chr10_+_40214877 5.97 ENSDART00000109689
GRAM domain containing 1Ba
chr13_+_25286538 5.93 ENSDART00000180282
conserved helix-loop-helix ubiquitous kinase
chr11_-_38513978 5.87 ENSDART00000123381
si:ch211-117k10.3
chr10_+_44824072 5.82 ENSDART00000162669
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr19_-_45960191 5.75 ENSDART00000052434
ENSDART00000172732
eukaryotic translation initiation factor 3, subunit H, b
chr10_-_27566481 5.70 ENSDART00000078920
autism susceptibility candidate 2a
chr1_+_5422439 5.55 ENSDART00000055047
ENSDART00000142248
serine/threonine kinase 16
chr5_+_51079504 5.35 ENSDART00000097466
family with sequence similarity 169, member Aa
chr22_+_16535575 5.33 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr22_-_9896180 5.24 ENSDART00000138343
zinc finger protein 990
chr7_+_73397283 5.08 ENSDART00000174390

chr13_+_28702104 5.08 ENSDART00000135481
si:ch211-67n3.9
chr12_-_7639120 4.92 ENSDART00000126712
ENSDART00000126219
coiled-coil domain containing 6b
chr1_-_19502322 4.86 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr13_-_30700460 4.86 ENSDART00000139073
Ras association (RalGDS/AF-6) domain family member 4
chr2_+_38742338 4.80 ENSDART00000177290
capping protein regulator and myosin 1 linker 3
chr22_+_2769236 4.80 ENSDART00000141836
si:dkey-20i20.10
chr20_-_6196989 4.77 ENSDART00000013343
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr9_-_10532591 4.73 ENSDART00000175269
thrombospondin, type I, domain containing 7Ba
chr8_-_22838364 4.72 ENSDART00000187954
ENSDART00000185368
ENSDART00000188210
MAGI family member, X-linked a
chr2_-_9818640 4.68 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, b
chr19_-_10196370 4.67 ENSDART00000091707
D site albumin promoter binding protein a
chr23_+_20705849 4.63 ENSDART00000079538
coiled-coil domain containing 30
chr23_-_33709964 4.57 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr15_-_11681653 4.49 ENSDART00000180160
fukutin related protein
chr9_-_32343673 4.42 ENSDART00000078499
raftlin family member 2
chr3_-_30434016 4.37 ENSDART00000150958
leucine rich repeat containing 4Ba
chr12_+_8168272 4.19 ENSDART00000054092
AT-rich interaction domain 5B
chr13_+_1944451 4.19 ENSDART00000125914
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr14_-_25111496 4.07 ENSDART00000158108
si:rp71-1d10.8
chr22_-_17585618 4.04 ENSDART00000183123
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr3_-_45250924 4.04 ENSDART00000109017
ubiquitin specific peptidase 31
chr18_-_47662696 4.03 ENSDART00000184260

chr8_-_39952727 3.98 ENSDART00000181310
calcium binding protein 1a
chr20_+_20750284 3.96 ENSDART00000181524
protein phosphatase 1, regulatory subunit 13Bb
chr20_-_40766387 3.90 ENSDART00000061173
hydroxysteroid dehydrogenase like 1
chr20_-_31075972 3.87 ENSDART00000122927
si:ch211-198b3.4
chr20_-_36617313 3.84 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr9_+_44431174 3.73 ENSDART00000149726
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_-_12371206 3.67 ENSDART00000161679
elongation factor like GTPase 1
chr21_-_26691959 3.66 ENSDART00000149702
ENSDART00000149840
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_+_6869847 3.63 ENSDART00000036646
dedicator of cytokinesis 4b
chr13_+_4409294 3.62 ENSDART00000146437
si:ch211-130h14.4
chr21_-_13972745 3.61 ENSDART00000143874
AT-hook transcription factor
chr7_-_71829649 3.41 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr19_-_3574060 3.38 ENSDART00000105120
transmembrane protein 170B
chr14_+_21820034 3.34 ENSDART00000122739
C-terminal binding protein 1
chr4_+_17655872 3.27 ENSDART00000066999
WASH complex subunit 3
chr17_-_18797245 3.27 ENSDART00000045991
vaccinia related kinase 1
chr6_+_45494227 3.23 ENSDART00000159863
contactin 4
chr6_+_13039951 3.14 ENSDART00000091700
ciliogenesis associated TTC17 interacting protein
chr8_+_668184 3.13 ENSDART00000183788
ring finger protein 165b
chr8_+_17775247 3.06 ENSDART00000112356
si:ch211-150o23.3
chr5_+_70271799 3.05 ENSDART00000101316
zinc finger protein 618
chr23_+_31942040 2.93 ENSDART00000088607
nuclear envelope integral membrane protein 1
chr13_-_49666615 2.85 ENSDART00000148083
translocase of outer mitochondrial membrane 20
chr11_+_42726712 2.82 ENSDART00000028955
tudor domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f3_pou4f1+pou4f4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 59.4 GO:0007638 mechanosensory behavior(GO:0007638)
12.6 37.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.9 79.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
6.8 27.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
5.9 17.8 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
4.6 13.9 GO:0042040 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
4.1 12.3 GO:0021577 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
2.9 46.2 GO:0008053 mitochondrial fusion(GO:0008053)
2.9 48.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
2.8 19.9 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
2.8 47.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
2.5 2.5 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
2.3 7.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
2.2 17.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
2.2 6.5 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
2.1 27.5 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
2.0 8.2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
1.8 5.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
1.8 28.2 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.7 14.0 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
1.7 32.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
1.7 27.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
1.5 35.6 GO:0030032 lamellipodium assembly(GO:0030032)
1.4 20.0 GO:0001964 startle response(GO:0001964)
1.3 9.2 GO:0021982 pineal gland development(GO:0021982)
1.3 10.3 GO:0090594 inflammatory response to wounding(GO:0090594)
1.3 3.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.2 3.7 GO:0042256 mature ribosome assembly(GO:0042256)
1.2 4.9 GO:0038093 Fc receptor signaling pathway(GO:0038093)
1.2 5.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.0 4.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.0 14.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.9 4.5 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.9 14.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.8 7.6 GO:0060036 notochord cell vacuolation(GO:0060036)
0.8 10.7 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.8 3.3 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.8 10.3 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.7 33.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 38.9 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.6 16.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.6 22.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.6 13.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6 22.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.6 2.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.6 1.7 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.5 3.7 GO:0034389 lipid particle organization(GO:0034389)
0.5 6.6 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.5 1.8 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.4 24.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.4 2.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.4 6.1 GO:0060325 face morphogenesis(GO:0060325)
0.4 10.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.3 31.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 2.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 7.6 GO:0007020 microtubule nucleation(GO:0007020)
0.3 4.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.3 1.3 GO:0015871 choline transport(GO:0015871)
0.3 22.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 7.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 19.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.3 12.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.3 13.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.3 4.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 28.1 GO:0006865 amino acid transport(GO:0006865)
0.2 8.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 5.7 GO:0021884 forebrain neuron development(GO:0021884)
0.2 8.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 5.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.2 4.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.2 29.8 GO:0030041 actin filament polymerization(GO:0030041)
0.2 6.6 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.2 11.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.6 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 9.2 GO:0006414 translational elongation(GO:0006414)
0.1 1.5 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 13.9 GO:0031101 fin regeneration(GO:0031101)
0.1 38.1 GO:0030334 regulation of cell migration(GO:0030334)
0.1 15.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 12.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.7 GO:0051443 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 5.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 4.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 3.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 4.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 13.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 1.3 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 13.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 6.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 2.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 2.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.9 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 6.2 GO:0044782 cilium organization(GO:0044782)
0.1 10.0 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.1 1.9 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 3.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 13.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 2.3 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 0.2 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 21.4 GO:0007420 brain development(GO:0007420)
0.0 0.5 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 26.6 GO:0030182 neuron differentiation(GO:0030182)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.4 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 2.8 GO:0006605 protein targeting(GO:0006605)
0.0 0.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.8 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 86.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
3.6 46.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
2.7 13.5 GO:0042584 chromaffin granule membrane(GO:0042584)
2.0 9.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.6 69.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.4 14.0 GO:0045171 intercellular bridge(GO:0045171)
1.3 84.6 GO:0031225 anchored component of membrane(GO:0031225)
1.0 5.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.9 12.3 GO:0014704 intercalated disc(GO:0014704)
0.8 2.5 GO:0060077 inhibitory synapse(GO:0060077)
0.7 22.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.7 35.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.7 3.3 GO:0071203 WASH complex(GO:0071203)
0.7 7.8 GO:0030893 meiotic cohesin complex(GO:0030893)
0.6 8.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.6 13.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.6 5.8 GO:0042788 polysomal ribosome(GO:0042788)
0.5 7.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5 4.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.4 58.7 GO:0008021 synaptic vesicle(GO:0008021)
0.3 21.7 GO:0031201 SNARE complex(GO:0031201)
0.3 7.6 GO:0045180 basal cortex(GO:0045180)
0.3 17.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 2.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 17.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.2 13.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 6.1 GO:0031941 filamentous actin(GO:0031941)
0.2 21.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 23.1 GO:0045177 apical part of cell(GO:0045177)
0.2 14.1 GO:0005871 kinesin complex(GO:0005871)
0.2 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 21.1 GO:0099572 postsynaptic specialization(GO:0099572)
0.1 1.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 11.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 79.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 30.5 GO:0005874 microtubule(GO:0005874)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 3.3 GO:0005795 Golgi stack(GO:0005795)
0.1 23.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle(GO:0030137) COPI-coated vesicle membrane(GO:0030663)
0.1 5.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 12.6 GO:0030424 axon(GO:0030424)
0.1 25.8 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.1 22.5 GO:0043005 neuron projection(GO:0043005)
0.1 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891) sarcolemma(GO:0042383)
0.1 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 3.4 GO:0005770 late endosome(GO:0005770)
0.0 4.9 GO:0043235 receptor complex(GO:0043235)
0.0 6.6 GO:0045202 synapse(GO:0045202)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 6.7 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 13.9 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
4.6 13.9 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
4.3 103.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
3.7 18.7 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
3.5 14.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
3.3 32.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
2.3 15.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
1.8 28.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
1.6 4.8 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
1.5 5.9 GO:0008384 IkappaB kinase activity(GO:0008384)
1.4 21.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.4 6.9 GO:0004385 guanylate kinase activity(GO:0004385)
1.4 27.3 GO:0003785 actin monomer binding(GO:0003785)
1.3 22.4 GO:0045159 myosin II binding(GO:0045159)
1.2 7.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 13.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.0 4.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
1.0 103.6 GO:0005254 chloride channel activity(GO:0005254)
0.8 6.5 GO:0001972 retinoic acid binding(GO:0001972)
0.8 10.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.7 40.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.7 27.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.7 51.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.6 13.5 GO:0008143 poly(A) binding(GO:0008143)
0.6 10.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.6 2.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 5.5 GO:0005522 profilin binding(GO:0005522)
0.5 21.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 2.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.4 14.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 2.0 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.4 8.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 16.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.4 13.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 8.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.4 8.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 15.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 1.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 10.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 7.0 GO:0043236 laminin binding(GO:0043236)
0.3 6.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 5.8 GO:0070122 isopeptidase activity(GO:0070122)
0.3 17.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 7.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 34.1 GO:0005179 hormone activity(GO:0005179)
0.3 2.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 18.9 GO:0051287 NAD binding(GO:0051287)
0.2 4.0 GO:0002039 p53 binding(GO:0002039)
0.2 27.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.2 7.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 9.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 4.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 35.8 GO:0005516 calmodulin binding(GO:0005516)
0.2 10.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 14.6 GO:0043130 ubiquitin binding(GO:0043130)
0.2 6.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 3.9 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 1.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 51.1 GO:0003924 GTPase activity(GO:0003924)
0.1 1.7 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.1 2.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.7 GO:0017022 myosin binding(GO:0017022)
0.1 4.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 33.8 GO:0015631 tubulin binding(GO:0015631)
0.1 37.5 GO:0051015 actin filament binding(GO:0051015)
0.1 7.6 GO:0046943 carboxylic acid transmembrane transporter activity(GO:0046943)
0.1 2.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 13.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 23.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 13.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.6 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 25.6 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.1 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 26.2 GO:0046983 protein dimerization activity(GO:0046983)
0.1 4.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.8 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 9.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 21.1 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 32.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 34.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 7.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 5.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.4 15.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.3 12.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 14.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 11.2 PID ATM PATHWAY ATM pathway
0.2 6.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 6.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 6.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 7.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 30.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.7 8.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.5 22.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.0 21.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.7 5.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 14.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 12.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 17.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 43.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.3 3.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 2.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 2.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 2.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 7.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 4.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 11.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 5.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 7.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism