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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pitx2

Z-value: 1.19

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Transcription factors associated with pitx2

Gene Symbol Gene ID Gene Info
ENSDARG00000036194 paired-like homeodomain 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pitx2dr11_v1_chr14_+_36218072_36218072-0.112.8e-01Click!

Activity profile of pitx2 motif

Sorted Z-values of pitx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_45510977 22.92 ENSDART00000090596
fibroblast growth factor 12b
chr12_+_47917971 12.06 ENSDART00000185933
thymus, brain and testes associated
chr13_+_24280380 9.33 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr5_+_24287927 7.26 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr9_-_34974143 6.91 ENSDART00000127295
zgc:172067
chr23_+_28731379 6.84 ENSDART00000047378
cortistatin
chr9_-_34974416 6.78 ENSDART00000077790
zgc:172067
chr19_+_12762887 6.18 ENSDART00000139909
melanocortin 5a receptor
chr21_+_22630627 6.15 ENSDART00000193092
si:dkeyp-69c1.7
chr25_+_6306885 6.02 ENSDART00000142705
ENSDART00000067510
cellular retinoic acid binding protein 1a
chr14_-_2270973 5.81 ENSDART00000180729
protocadherin 2 alpha b 9
chr21_+_22630297 5.53 ENSDART00000147175
si:dkeyp-69c1.7
chr4_+_6643421 5.50 ENSDART00000099462
G protein-coupled receptor 85
chr5_-_23277939 5.38 ENSDART00000003514
proteolipid protein 1b
chr7_-_48173440 5.36 ENSDART00000124075
metastasis suppressor 1-like b
chr2_-_2020044 5.33 ENSDART00000024135
tubulin, beta 2A class IIa
chr13_-_30028103 5.28 ENSDART00000183889
stearoyl-CoA desaturase b
chr5_-_20205075 5.17 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr25_-_13839743 4.97 ENSDART00000158780
mitogen-activated protein kinase 8 interacting protein 1a
chr24_+_34085940 4.93 ENSDART00000171189
ankyrin repeat and SOCS box containing 10
chr5_-_72125551 4.72 ENSDART00000149412
SET and MYND domain containing 1a
chr9_-_43142636 4.67 ENSDART00000134349
ENSDART00000181835
coiled-coil domain containing 141
chr19_-_9829965 4.66 ENSDART00000136842
ENSDART00000142766
calcium channel, voltage-dependent, gamma subunit 8a
chr7_-_57933736 4.62 ENSDART00000142580
ankyrin 2b, neuronal
chr11_-_4235811 4.60 ENSDART00000121716
si:ch211-236d3.4
chr23_-_24856025 4.59 ENSDART00000142171
synaptotagmin VIa
chr1_+_7546259 4.40 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr23_+_40109353 4.24 ENSDART00000149249
growth hormone releasing hormone receptor, like
chr21_+_10756154 4.20 ENSDART00000074833
retinal homeobox gene 3
chr1_+_33383644 4.17 ENSDART00000187194
dehydrogenase/reductase (SDR family) X-linked
chr9_+_307863 4.16 ENSDART00000163474
SH3 and cysteine rich domain 3
chr20_+_36233873 4.15 ENSDART00000131867
cornichon family AMPA receptor auxiliary protein 3
chr8_+_27807974 4.12 ENSDART00000078509
capping protein (actin filament) muscle Z-line, alpha 1b
chr9_-_12034444 4.03 ENSDART00000038651
zinc finger protein 804A
chr10_+_29963518 3.97 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
neurotrimin
chr7_-_22132265 3.95 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr19_-_25271155 3.90 ENSDART00000104027
regulating synaptic membrane exocytosis 3
chr8_+_554531 3.85 ENSDART00000193623

chr17_+_5915875 3.75 ENSDART00000184179
fibronectin type III domain containing 4b
chr6_-_54126463 3.74 ENSDART00000161059
tumor suppressor candidate 2a
chr2_-_42871286 3.72 ENSDART00000087823
adenylate cyclase 8 (brain)
chr17_-_5583345 3.67 ENSDART00000035944
chloride intracellular channel 5a
chr21_+_13366353 3.62 ENSDART00000151630
si:ch73-62l21.1
chr25_-_19090479 3.61 ENSDART00000027465
ENSDART00000177670
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr21_+_10866421 3.57 ENSDART00000137858
alpha-kinase 2
chr19_-_28283844 3.54 ENSDART00000151756
ENSDART00000079104
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr2_-_6292510 3.52 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr4_+_8168514 3.41 ENSDART00000150830
ninjurin 2
chr18_+_26337869 3.40 ENSDART00000109257
si:ch211-234p18.3
chr9_-_32753535 3.38 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr16_-_43971258 3.36 ENSDART00000141941
zinc finger protein, FOG family member 2a
chr13_-_24448278 3.35 ENSDART00000057584
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_+_6116503 3.35 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr23_+_40604951 3.34 ENSDART00000114959
cadherin 24, type 2a
chr24_+_24461341 3.28 ENSDART00000147658
basic helix-loop-helix family, member e22
chr10_-_43392267 3.23 ENSDART00000142872
EGF-like repeats and discoidin I-like domains 3b
chr10_+_15777064 3.22 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr1_-_1894722 3.22 ENSDART00000165669
si:ch211-132g1.3
chr14_-_2206476 3.20 ENSDART00000081870
protocadherin 2 alpha b 6
chr16_-_13004166 3.18 ENSDART00000133735
calcium channel, voltage-dependent, gamma subunit 7b
chr6_+_45347219 3.16 ENSDART00000188240

chr10_+_15777258 3.13 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr24_-_27400630 3.13 ENSDART00000165760
chemokine (C-C motif) ligand 34b, duplicate 1
chr9_-_29321625 3.11 ENSDART00000158689
ENSDART00000014047
ENSDART00000122602
parathyroid hormone 2 receptor
chr14_+_44545092 3.10 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr13_+_16522608 3.06 ENSDART00000182838
ENSDART00000143200
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr15_-_12319065 3.06 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr13_+_52071971 3.04 ENSDART00000184775

chr3_+_15296824 3.03 ENSDART00000043801
calcium binding protein 5b
chr1_-_43987873 3.01 ENSDART00000108821

chr10_-_7857494 3.00 ENSDART00000143215
inositol polyphosphate-5-phosphatase Ja
chr23_+_8989168 3.00 ENSDART00000034380
XK, Kell blood group complex subunit-related family, member 7
chr21_-_32467099 2.98 ENSDART00000186354
zgc:123105
chr10_+_21511495 2.92 ENSDART00000178395

chr23_+_22267374 2.89 ENSDART00000079035
RAP1 GTPase activating protein
chr25_+_35019693 2.89 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr10_+_26926654 2.81 ENSDART00000078980
ENSDART00000100289
RAB1B, member RAS oncogene family b
chr18_+_48608366 2.76 ENSDART00000151229
potassium inwardly-rectifying channel, subfamily J, member 5
chr12_+_48216662 2.76 ENSDART00000187369
leucine rich repeat containing 20
chr6_-_36182115 2.68 ENSDART00000154639
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr21_+_41743493 2.64 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr18_-_21806613 2.61 ENSDART00000145721
neuritin 1-like a
chr5_+_24282570 2.58 ENSDART00000041905
zinc finger, DHHC-type containing 23a
chr9_+_33216945 2.56 ENSDART00000134029
si:ch211-125e6.12
chr6_-_6248893 2.53 ENSDART00000124662
reticulon 4a
chr7_+_24115082 2.48 ENSDART00000182718
mitochondrial ribosomal protein L52
chr23_+_33934228 2.47 ENSDART00000134237
si:ch211-148l7.4
chr5_-_38094130 2.46 ENSDART00000131831
si:ch211-284e13.4
chr20_-_18731268 2.46 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr23_-_24825863 2.45 ENSDART00000112493
synaptotagmin VIa
chr17_-_43552894 2.45 ENSDART00000181226
ENSDART00000188125
5'-nucleotidase, cytosolic IAb
chr25_-_7999756 2.44 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr13_-_30149973 2.41 ENSDART00000041515
secretion associated, Ras related GTPase 1Ab
chr5_-_67145505 2.40 ENSDART00000011295
retinal outer segment membrane protein 1a
chr5_+_37978501 2.39 ENSDART00000012050
apolipoprotein A-Ia
chr1_+_38758261 2.38 ENSDART00000182756
WD repeat domain 17
chr17_+_33495194 2.37 ENSDART00000033691
parathyroid hormone 2
chr9_-_23747264 2.34 ENSDART00000141461
ENSDART00000010311
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr5_+_52067723 2.33 ENSDART00000166902
SET binding protein 1
chr7_+_15872357 2.33 ENSDART00000165757
paired box 6b
chr20_+_41640687 2.32 ENSDART00000138686
family with sequence similarity 184, member A
chr13_-_30027730 2.31 ENSDART00000044009
stearoyl-CoA desaturase b
chr16_-_26820634 2.27 ENSDART00000111156
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_-_31767827 2.25 ENSDART00000114928
actinodin2
chr5_-_29488245 2.25 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr1_+_38758445 2.24 ENSDART00000136300
WD repeat domain 17
chr11_-_44409856 2.22 ENSDART00000162886
interleukin 1 receptor accessory protein-like 1b
chr1_+_11881559 2.20 ENSDART00000166981
sorting nexin 8b
chr9_-_42989297 2.20 ENSDART00000126871
titin, tandem duplicate 2
chr14_-_2264494 2.19 ENSDART00000191149
protocadherin 2 alpha b 9
chr20_-_29482492 2.18 ENSDART00000178308
actin, alpha, cardiac muscle 1a
chr19_+_37701450 2.18 ENSDART00000087694
thrombospondin, type I, domain containing 7Aa
chr19_-_40776267 2.17 ENSDART00000189038
calcitonin receptor
chr18_+_9323211 2.17 ENSDART00000166114
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr25_+_25124684 2.15 ENSDART00000167542
lactate dehydrogenase A4
chr17_-_47142249 2.13 ENSDART00000184705

chr20_-_30369598 2.12 ENSDART00000144549
allantoicase
chr7_+_30970045 2.11 ENSDART00000155974
tight junction protein 1a
chr7_-_65191937 2.10 ENSDART00000173234
polycystic kidney disease 1 like 2a
chr22_-_25469751 2.09 ENSDART00000171670

chr8_+_50983551 2.06 ENSDART00000142061
si:dkey-32e23.4
chr21_+_20715020 2.06 ENSDART00000015224
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr6_-_9581949 2.06 ENSDART00000144335
cytochrome P450, family 27, subfamily C, polypeptide 1
chr11_-_28148033 2.05 ENSDART00000177182
lactamase, beta-like 1b
chr21_+_21738150 2.05 ENSDART00000150974
odorant receptor, family E, subfamily 124, member 4
chr8_+_7737062 2.05 ENSDART00000166712
FYVE, RhoGEF and PH domain containing 1
chr24_+_2470061 2.02 ENSDART00000140383
ENSDART00000191261
coagulation factor XIII A chain
chr25_+_35020529 2.01 ENSDART00000158016
filamin C, gamma a (actin binding protein 280)
chr17_-_17759138 2.01 ENSDART00000157128
ENSDART00000123845
aarF domain containing kinase 1
chr23_+_9867483 2.00 ENSDART00000023099
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr21_-_21790372 1.99 ENSDART00000151094
X-ray radiation resistance associated 1
chr10_-_25204034 1.98 ENSDART00000161100
si:ch211-214k5.6
chr19_+_19747430 1.98 ENSDART00000166129
homeobox A9a
chr19_+_42898239 1.96 ENSDART00000051724
cAMP-regulated phosphoprotein, 21
chr10_-_25823258 1.96 ENSDART00000064327
finTRIM family, member 54
chr14_+_743346 1.94 ENSDART00000110511
klotho beta
chr9_-_1986014 1.93 ENSDART00000142842
homeobox D12a
chr8_+_35356944 1.93 ENSDART00000143243
si:dkeyp-14d3.1
chr20_+_18225329 1.93 ENSDART00000144172
potassium channel tetramerization domain containing 1
chr11_+_6116096 1.93 ENSDART00000159680
nuclear receptor subfamily 2, group F, member 6b
chr24_-_10006158 1.92 ENSDART00000106244
zgc:171750
chr7_+_29167744 1.91 ENSDART00000076345
solute carrier family 38, member 8b
chr1_-_57129179 1.90 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr6_+_37894914 1.87 ENSDART00000148817
oculocutaneous albinism II
chr11_-_16093018 1.87 ENSDART00000139309
ENSDART00000139819
si:dkey-205k8.5
chr11_-_1933793 1.86 ENSDART00000186850
Fas apoptotic inhibitory molecule 2b
chr22_+_696931 1.84 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr10_+_8534750 1.84 ENSDART00000183960
TBC1 domain family, member 10Ab
chr15_-_31390985 1.84 ENSDART00000060117
odorant receptor, family D, subfamily 111, member 6
chr4_+_5848229 1.83 ENSDART00000161101
ENSDART00000067357
LYR motif containing 5a
chr23_+_43849190 1.83 ENSDART00000017375
cyclic nucleotide gated channel alpha 1
chr9_-_53537989 1.83 ENSDART00000114022
SLIT and NTRK-like family, member 5b
chr12_+_36416173 1.81 ENSDART00000190278
unkempt family zinc finger
chr2_+_6253246 1.80 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr20_-_20533865 1.79 ENSDART00000125039
SIX homeobox 6b
chr11_-_29563437 1.78 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr13_+_9896845 1.76 ENSDART00000169076
si:ch211-117n7.8
chr17_-_50331351 1.76 ENSDART00000149294
otoferlin b
chr6_-_39903393 1.72 ENSDART00000085945
Ts translation elongation factor, mitochondrial
chr4_-_40883162 1.70 ENSDART00000151978
zinc finger protein 1102
chr18_-_6534516 1.68 ENSDART00000009217
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr7_+_53413445 1.67 ENSDART00000190480
zinc finger protein 609b
chr2_+_38731696 1.66 ENSDART00000181733

chr11_-_3574311 1.66 ENSDART00000167064
si:dkey-33m11.7
chr18_+_21061216 1.65 ENSDART00000141739
family with sequence similarity 169, member B
chr12_+_28995942 1.65 ENSDART00000076334
vertebrate ancient long opsin b
chr7_-_16204885 1.65 ENSDART00000171008
bloodthirsty-related gene family, member 5
chr12_+_316238 1.64 ENSDART00000187492
recoverin b
chr8_-_22157301 1.61 ENSDART00000158383
nephronophthisis 4
chr1_-_26293203 1.59 ENSDART00000180140
CXXC finger 4
chr4_+_38002643 1.58 ENSDART00000160860
zinc finger protein 1051
chr6_+_21740672 1.58 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr22_-_25502977 1.57 ENSDART00000181749

chr5_+_64840656 1.56 ENSDART00000073953
leucine rich repeat containing 8 VRAC subunit Ab
chr17_-_53328043 1.56 ENSDART00000171082
exonuclease 3'-5' domain containing 1
chr23_-_27505825 1.54 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr2_+_24931677 1.54 ENSDART00000021528
angiotensin II receptor, type 1a
chr8_-_36125849 1.54 ENSDART00000159581

chr20_+_25581627 1.52 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr17_-_50040927 1.51 ENSDART00000184304

chr2_-_11258547 1.50 ENSDART00000165803
ENSDART00000193817
solute carrier family 44, member 5a
chr25_-_35047838 1.50 ENSDART00000155060

chr2_-_2096055 1.49 ENSDART00000126566
solute carrier family 22, member 23
chr8_+_41533268 1.49 ENSDART00000142377
si:ch211-158d24.2
chr17_-_16342388 1.48 ENSDART00000017930
potassium channel, subfamily K, member 13a
chr7_+_24114694 1.47 ENSDART00000127177
mitochondrial ribosomal protein L52
chr18_-_39702327 1.46 ENSDART00000149158
Dmx-like 2
chr11_-_43002262 1.46 ENSDART00000172477
ENSDART00000181513

chr16_-_45910050 1.46 ENSDART00000133213
antifreeze protein type IV
chr10_+_36150911 1.45 ENSDART00000076804
Wnt-activated inhibitory factor 2
chr1_-_10577945 1.45 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
transient receptor potential cation channel, subfamily C, member 5a
chr6_+_18520859 1.44 ENSDART00000158263
si:dkey-10p5.10
chr23_+_3596401 1.44 ENSDART00000185908
si:dkey-9l20.3
chr14_+_41518257 1.42 ENSDART00000050037
cholinergic receptor, nicotinic, beta 3b (neuronal)
chr21_+_13127742 1.40 ENSDART00000179221
outer dense fiber of sperm tails 2a
chr15_-_37929135 1.40 ENSDART00000157550
si:dkey-238d18.15
chr14_-_41535822 1.39 ENSDART00000149407
integrin, alpha 6, like
chr7_+_42208859 1.38 ENSDART00000148643
phosphorylase kinase, beta
chr8_+_694218 1.37 ENSDART00000147753
ring finger protein 165b
chr21_-_33032715 1.35 ENSDART00000065349
ENSDART00000191502
ENSDART00000149386
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of pitx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.6 22.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.4 4.2 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
1.3 5.2 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
1.2 6.0 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
1.0 2.9 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.9 4.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.8 3.4 GO:0021742 abducens nucleus development(GO:0021742)
0.8 4.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.7 3.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.7 2.1 GO:0000256 allantoin catabolic process(GO:0000256)
0.7 13.7 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.6 2.4 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.6 1.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 2.3 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.5 4.9 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.5 5.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 2.5 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.5 1.5 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.5 2.4 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.5 7.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.4 2.2 GO:0016322 neuron remodeling(GO:0016322)
0.4 2.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 2.8 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.4 1.6 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.4 3.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.4 3.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.4 4.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.4 2.2 GO:0003272 endocardial cushion formation(GO:0003272)
0.4 2.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.4 3.9 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.3 1.0 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 3.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 5.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 1.9 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 3.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 3.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 5.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 2.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 8.8 GO:0007340 acrosome reaction(GO:0007340)
0.3 5.4 GO:0097178 ruffle assembly(GO:0097178)
0.3 3.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 2.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.0 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2 4.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 8.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.6 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 2.6 GO:0035094 response to nicotine(GO:0035094)
0.2 1.9 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 2.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 2.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 2.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 2.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 3.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 0.3 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.2 22.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.2 4.7 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 0.7 GO:0061440 renal system vasculature development(GO:0061437) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012)
0.1 1.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 2.0 GO:0046847 filopodium assembly(GO:0046847)
0.1 8.4 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.5 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 9.3 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 3.9 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.6 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.7 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.6 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.4 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 4.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 2.0 GO:0010165 response to X-ray(GO:0010165)
0.1 3.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.9 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.5 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 1.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 3.3 GO:0034332 adherens junction organization(GO:0034332)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 5.0 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 1.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.5 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.1 0.6 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 2.2 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 14.4 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 3.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.1 0.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.7 GO:0070989 oxidative demethylation(GO:0070989)
0.1 4.6 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 1.1 GO:0032418 lysosome localization(GO:0032418)
0.1 1.3 GO:0043486 histone exchange(GO:0043486)
0.1 1.3 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135) positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 3.1 GO:0007602 phototransduction(GO:0007602)
0.1 0.9 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 1.5 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.5 GO:0030431 sleep(GO:0030431)
0.0 2.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.0 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.9 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 2.4 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 9.7 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 9.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.8 GO:0099590 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) neurotransmitter receptor internalization(GO:0099590)
0.0 1.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 4.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 2.4 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.0 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 2.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:0036269 swimming behavior(GO:0036269)
0.0 7.1 GO:0030334 regulation of cell migration(GO:0030334)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.4 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.3 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 5.7 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 2.9 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 4.3 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0 2.1 GO:0051216 cartilage development(GO:0051216)
0.0 7.4 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0021782 glial cell development(GO:0021782)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0060077 inhibitory synapse(GO:0060077)
1.0 4.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.5 8.8 GO:0030315 T-tubule(GO:0030315)
0.5 8.6 GO:0005869 dynactin complex(GO:0005869)
0.4 1.5 GO:0043291 RAVE complex(GO:0043291)
0.3 1.6 GO:1990923 PET complex(GO:1990923)
0.3 5.9 GO:0031430 M band(GO:0031430)
0.2 2.4 GO:0042627 chylomicron(GO:0042627)
0.2 7.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.2 6.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.0 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 2.1 GO:0043209 myelin sheath(GO:0043209)
0.1 7.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 8.8 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 1.6 GO:0097546 ciliary base(GO:0097546)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.1 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.4 GO:0005903 brush border(GO:0005903)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 9.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.9 GO:0030496 midbody(GO:0030496)
0.1 2.2 GO:0043679 axon terminus(GO:0043679)
0.1 8.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 5.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.0 GO:0001726 ruffle(GO:0001726)
0.0 1.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 4.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 5.5 GO:0005874 microtubule(GO:0005874)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0005930 axoneme(GO:0005930)
0.0 1.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.0 GO:0030425 dendrite(GO:0030425)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.3 5.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
1.0 8.1 GO:0001972 retinoic acid binding(GO:0001972)
1.0 26.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 2.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.7 2.2 GO:0097643 amylin receptor activity(GO:0097643)
0.7 4.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.7 6.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.6 1.8 GO:1990715 mRNA CDS binding(GO:1990715)
0.6 2.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 2.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 1.9 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 1.5 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.4 3.0 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.3 2.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 3.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3 6.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 4.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 2.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 2.1 GO:0004096 catalase activity(GO:0004096)
0.2 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 11.0 GO:0005178 integrin binding(GO:0005178)
0.2 8.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 16.2 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 3.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 14.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.2 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 4.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 1.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 3.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.4 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 3.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 7.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 3.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.2 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.0 7.1 GO:0005179 hormone activity(GO:0005179)
0.0 5.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 4.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 4.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 3.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 7.4 GO:0003924 GTPase activity(GO:0003924)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 10.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.7 GO:0032451 demethylase activity(GO:0032451)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 2.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 2.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.7 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.2 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 4.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 2.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 6.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 5.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.9 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination