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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pax2b

Z-value: 1.56

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Transcription factors associated with pax2b

Gene Symbol Gene ID Gene Info
ENSDARG00000032578 paired box 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax2bdr11_v1_chr12_-_45876387_458763870.391.1e-04Click!

Activity profile of pax2b motif

Sorted Z-values of pax2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_10720294 10.70 ENSDART00000139387
ATPase Na+/K+ transporting subunit beta 1b
chr16_-_45069882 8.56 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_+_25112269 7.73 ENSDART00000147546
ndrg family member 3a
chr22_-_11136625 7.30 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr2_-_38000276 7.08 ENSDART00000034790
Purkinje cell protein 4 like 1
chr7_+_38770167 6.91 ENSDART00000190827
Rho GTPase activating protein 1
chr24_-_7632187 6.73 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr7_-_42206720 6.50 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr23_-_4915118 6.37 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr24_-_17023392 6.36 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr24_-_6158933 6.36 ENSDART00000021609
glutamate decarboxylase 2
chr15_+_28989573 6.28 ENSDART00000076648
CAP-GLY domain containing linker protein 3
chr18_-_7137153 6.17 ENSDART00000019571
CD9 molecule a
chr11_-_10798021 5.33 ENSDART00000167112
ENSDART00000179725
ENSDART00000091923
ENSDART00000185825
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr7_-_30082931 5.14 ENSDART00000075600
tetraspanin 3b
chr16_+_10777116 5.05 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr21_-_39628771 4.99 ENSDART00000183995
aldolase C, fructose-bisphosphate, b
chr3_-_32362872 4.94 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr8_-_25002182 4.94 ENSDART00000078792
adenosylhomocysteinase-like 1
chr24_+_31334209 4.69 ENSDART00000168837
ENSDART00000172473
family with sequence similarity 168, member B
chr15_-_163586 4.62 ENSDART00000163597
septin-4
chr4_-_5302866 4.58 ENSDART00000138590
si:ch211-214j24.9
chr12_+_16953415 4.52 ENSDART00000020824
pantothenate kinase 1b
chr21_+_13861589 4.47 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr20_+_20637866 4.46 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr4_+_9669717 4.42 ENSDART00000004604
si:dkey-153k10.9
chr2_+_42871831 4.41 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr25_-_21156678 4.40 ENSDART00000156257
WNK lysine deficient protein kinase 1a
chr2_-_33687214 4.36 ENSDART00000147439
ATPase H+ transporting V0 subunit b
chr7_-_44605050 4.36 ENSDART00000148471
ENSDART00000149072
thymidine kinase 2, mitochondrial
chr10_+_15777258 4.31 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr12_-_33972798 4.30 ENSDART00000105545
ADP-ribosylation factor-like 3
chr8_+_25761654 4.27 ENSDART00000137899
ENSDART00000062403
transmembrane protein 9
chr2_-_39759059 4.16 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr14_-_24410673 4.16 ENSDART00000125923
chemokine (C-X-C motif) ligand 14
chr8_+_26292560 4.13 ENSDART00000053463
monoglyceride lipase
chr7_+_44715224 3.97 ENSDART00000184630
si:dkey-56m19.5
chr18_+_43183749 3.92 ENSDART00000151166
nectin cell adhesion molecule 1b
chr2_-_31302615 3.92 ENSDART00000034784
ENSDART00000060812
adenylate cyclase activating polypeptide 1b
chr14_+_22172047 3.91 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr8_+_16758304 3.90 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr7_-_32895668 3.90 ENSDART00000141828
anoctamin 5b
chr19_+_33093395 3.89 ENSDART00000019459
family with sequence similarity 91, member A1
chr24_+_39158283 3.82 ENSDART00000053139
ATPase H+ transporting V0 subunit cb
chr19_-_42416696 3.78 ENSDART00000086961
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr20_+_29743904 3.75 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr15_-_20956384 3.75 ENSDART00000135770
tubulin folding cofactor E-like a
chr3_+_40576447 3.74 ENSDART00000083212
fascin actin-bundling protein 1a
chr21_+_22400951 3.69 ENSDART00000134592
LMBR1 domain containing 2b
chr11_+_37275448 3.68 ENSDART00000161423
cysteine-rich with EGF-like domains 1a
chr20_+_27393668 3.65 ENSDART00000005473
transmembrane protein 179
chr16_+_25761101 3.62 ENSDART00000110619
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr16_+_23960744 3.60 ENSDART00000058965
apolipoprotein Eb
chr13_+_421231 3.56 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr3_-_15264698 3.56 ENSDART00000111948
ENSDART00000142594
seizure related 6 homolog (mouse)-like 2
chr25_-_13871118 3.55 ENSDART00000160866
cryptochrome circadian clock 2
chr1_+_45707219 3.54 ENSDART00000143363
si:ch211-214c7.4
chr16_+_10841163 3.53 ENSDART00000065467
death effector domain-containing 1
chr25_+_13791627 3.51 ENSDART00000159278
zgc:92873
chr6_+_48041759 3.50 ENSDART00000140086
si:dkey-92f12.2
chr24_-_33756003 3.49 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr10_+_16501699 3.48 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr20_-_20610812 3.45 ENSDART00000181870
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr2_+_30786773 3.40 ENSDART00000019029
ENSDART00000145681
ATPase H+ transporting V1 subunit H
chr1_-_10473630 3.38 ENSDART00000040116
trinucleotide repeat containing 5
chr18_+_40381102 3.37 ENSDART00000136588
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr10_+_23060391 3.36 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr9_+_17429170 3.34 ENSDART00000006256
zgc:101559
chr2_-_24996441 3.34 ENSDART00000144795
solute carrier family 35, member G2a
chr3_+_27713610 3.32 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr4_+_73973242 3.32 ENSDART00000182529

chr16_+_23960933 3.31 ENSDART00000146077
apolipoprotein Eb
chr15_+_16387088 3.31 ENSDART00000101789
flotillin 2b
chr23_+_24973773 3.26 ENSDART00000047020
caspase 9, apoptosis-related cysteine peptidase
chr13_-_23007813 3.26 ENSDART00000057638
hexokinase 1
chr13_+_11439486 3.25 ENSDART00000138312
zinc finger and BTB domain containing 18
chr10_+_20108557 3.25 ENSDART00000142708
dematin actin binding protein
chr19_-_26823647 3.24 ENSDART00000002464
neuraminidase 1
chr5_+_33301005 3.23 ENSDART00000006021
ubiquitin specific peptidase 20
chr22_-_21176269 3.23 ENSDART00000112839
required for excision 1-B domain containing
chr2_+_30787128 3.21 ENSDART00000189233
ATPase H+ transporting V1 subunit H
chr24_+_12989727 3.20 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr18_+_26337869 3.20 ENSDART00000109257
si:ch211-234p18.3
chr17_+_5895500 3.20 ENSDART00000019905
fibronectin type III domain containing 4b
chr4_-_5247335 3.19 ENSDART00000050221
ATPase H+ transporting V1 subunit E1b
chr23_+_44741500 3.18 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr2_-_30460293 3.17 ENSDART00000113193
cerebellin 2a precursor
chr15_+_32798333 3.17 ENSDART00000162370
ENSDART00000166525
spartin b
chr1_-_46924801 3.17 ENSDART00000142560
pyridoxal (pyridoxine, vitamin B6) kinase b
chr8_+_31248917 3.16 ENSDART00000112170
un-named hu7912
chr24_-_4148914 3.15 ENSDART00000033494
ENSDART00000147849
Kruppel-like factor 6a
chr14_+_14847304 3.13 ENSDART00000169932
coiled-coil domain containing 142
chr5_+_57320113 3.12 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr18_+_17428506 3.11 ENSDART00000100223
zgc:91860
chr11_+_5817202 3.07 ENSDART00000126084
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr23_-_29505463 3.06 ENSDART00000050915
kinesin family member 1B
chr15_-_19250543 3.05 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr19_+_551963 3.03 ENSDART00000110495
A kinase (PRKA) anchor protein 9
chr11_+_5499661 3.03 ENSDART00000027850
solute carrier family 35, member E1
chr1_+_45671687 3.01 ENSDART00000146101
mucolipin 1a
chr17_+_21964472 3.00 ENSDART00000063704
ENSDART00000188904
cysteine-rich protein 3
chr3_-_37785873 2.99 ENSDART00000011691
BCL2 associated X, apoptosis regulator a
chr24_-_10828560 2.95 ENSDART00000132282
family with sequence similarity 49, member Bb
chr4_+_16885854 2.94 ENSDART00000017726
ethanolamine kinase 1
chr19_-_20114149 2.93 ENSDART00000052620
neuropeptide Y
chr21_+_22878991 2.88 ENSDART00000186399
PCF11 cleavage and polyadenylation factor subunit
chr19_-_12193622 2.88 ENSDART00000041960
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_-_31505144 2.87 ENSDART00000087115
regulating synaptic membrane exocytosis 1b
chr3_-_21062706 2.87 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
family with sequence similarity 57, member Ba
chr19_+_33093577 2.86 ENSDART00000180317
family with sequence similarity 91, member A1
chr10_-_7702029 2.85 ENSDART00000018017
germ cell-less, spermatogenesis associated 1
chr9_-_1703761 2.85 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
heterogeneous nuclear ribonucleoprotein A3
chr23_+_37086159 2.85 ENSDART00000074407
ceramide-1-phosphate transfer protein
chr16_+_14216581 2.84 ENSDART00000113093
glucosidase, beta, acid
chr13_+_35925490 2.82 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr23_-_16692312 2.81 ENSDART00000046784
FK506 binding protein 1Ab
chr10_+_25219728 2.81 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr7_-_28696556 2.81 ENSDART00000148822
adhesion G protein-coupled receptor G1
chr5_+_11812089 2.80 ENSDART00000111359
F-box protein 21
chr11_-_22372072 2.80 ENSDART00000065996
transmembrane protein 183A
chr21_+_22878834 2.79 ENSDART00000065562
PCF11 cleavage and polyadenylation factor subunit
chr18_-_22094102 2.79 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr22_-_26852516 2.77 ENSDART00000005829
glycerophosphodiester phosphodiesterase 1
chr9_+_34641237 2.73 ENSDART00000133996
short stature homeobox
chr19_-_17774875 2.73 ENSDART00000151133
ENSDART00000130695
DNA topoisomerase II beta
chr16_-_16237844 2.72 ENSDART00000168747
ENSDART00000111912
RNA binding motif protein 12B
chr12_+_24342303 2.72 ENSDART00000111239
neurexin 1a
chr7_-_41013575 2.71 ENSDART00000150139
insulin induced gene 1
chr18_+_6857071 2.69 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr11_-_1291012 2.68 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr10_-_7974155 2.67 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr3_-_21106093 2.67 ENSDART00000156566
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr21_-_42100471 2.66 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_+_301898 2.66 ENSDART00000157246
zinc finger protein 1008
chr22_+_17399124 2.66 ENSDART00000145769
RAB GTPase activating protein 1-like
chr9_+_21819082 2.66 ENSDART00000136902
ENSDART00000101991
thioredoxin domain containing 9
chr25_+_1591964 2.65 ENSDART00000093277
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr9_+_28103735 2.64 ENSDART00000007789
isocitrate dehydrogenase 1 (NADP+), soluble
chr7_+_57795974 2.64 ENSDART00000148369
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr1_+_7956030 2.64 ENSDART00000159655

chr2_+_33189582 2.63 ENSDART00000145588
ENSDART00000136330
ENSDART00000139295
ENSDART00000086340
ring finger protein 220a
chr23_-_12345764 2.63 ENSDART00000133956
phosphatase and actin regulator 3a
chr13_+_2357637 2.63 ENSDART00000017148
glutamate-cysteine ligase, catalytic subunit
chr2_-_54387550 2.62 ENSDART00000097388
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr6_+_27667359 2.61 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr8_+_26083808 2.60 ENSDART00000099283
DALR anticodon binding domain containing 3
chr1_+_47091468 2.60 ENSDART00000036783
crystallin, zeta (quinone reductase)-like 1
chr15_+_28685892 2.58 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr16_+_31853919 2.58 ENSDART00000133886
atrophin 1
chr19_+_8985230 2.57 ENSDART00000018973
secretory carrier membrane protein 3
chr5_-_22130937 2.56 ENSDART00000138606
LAS1-like, ribosome biogenesis factor
chr23_+_33718602 2.55 ENSDART00000024695
DAZ associated protein 2
chr14_+_8947282 2.55 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr17_-_50010121 2.53 ENSDART00000122747
transmembrane protein 30Aa
chr8_-_30944465 2.52 ENSDART00000128792
ENSDART00000191717
ENSDART00000049944
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a
chr19_-_5103313 2.52 ENSDART00000037007
triosephosphate isomerase 1a
chr16_-_2558653 2.51 ENSDART00000110365
adenylate cyclase 3a
chr8_-_44904723 2.51 ENSDART00000040804
PRA1 domain family, member 2
chr13_-_45022527 2.51 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr2_-_31614277 2.51 ENSDART00000137054
ENSDART00000131507
ENSDART00000137674
ENSDART00000147041
si:ch211-106h4.5
chr3_+_32832538 2.50 ENSDART00000139410
CD2 (cytoplasmic tail) binding protein 2
chr7_+_42206847 2.49 ENSDART00000149250
phosphorylase kinase, beta
chr19_-_5103141 2.49 ENSDART00000150952
triosephosphate isomerase 1a
chr9_-_18743012 2.48 ENSDART00000131626
TSC22 domain family, member 1
chr21_+_21743599 2.47 ENSDART00000101700
polymerase (DNA-directed), delta 3, accessory subunit
chr2_+_41526904 2.47 ENSDART00000127520
activin A receptor, type 1 like
chr14_+_597532 2.46 ENSDART00000159805

chr20_-_26060154 2.44 ENSDART00000151950
serine active site containing 1
chr4_-_16836006 2.42 ENSDART00000010777
lactate dehydrogenase Ba
chr17_-_7861219 2.42 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr7_+_26224211 2.40 ENSDART00000173999
VGF nerve growth factor inducible
chr7_-_28647959 2.38 ENSDART00000150148
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr13_-_33022372 2.38 ENSDART00000147165
RNA binding motif protein 25a
chr5_-_41103583 2.38 ENSDART00000051070
ENSDART00000074781
golgi phosphoprotein 3
chr2_+_42177113 2.36 ENSDART00000056441
transmembrane protein with EGF-like and two follistatin-like domains 1a
chr1_-_45614318 2.35 ENSDART00000149725
activating transcription factor 7 interacting protein
chr3_-_26191960 2.34 ENSDART00000113843
yippee-like 3
chr5_-_19006290 2.33 ENSDART00000137022
golgin A3
chr25_-_19443421 2.33 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr18_+_26086803 2.32 ENSDART00000187911
zinc finger protein 710a
chr13_+_25505580 2.32 ENSDART00000140634
inositol polyphosphate-5-phosphatase F
chr2_+_20430366 2.31 ENSDART00000155108
si:ch211-153l6.6
chr2_+_12255568 2.30 ENSDART00000184164
ENSDART00000013454
phosphoribosyl transferase domain containing 1
chr23_-_35483163 2.30 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
F-box protein 25
chr7_-_41812015 2.30 ENSDART00000174058
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr23_-_36724575 2.29 ENSDART00000159560
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr8_+_24854600 2.28 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr3_-_50277959 2.28 ENSDART00000082773
ENSDART00000139524
ADP-ribosylation factor-like 16
chr22_+_16759010 2.27 ENSDART00000079638
ENSDART00000113099
TM2 domain containing 1
chr1_+_6135176 2.27 ENSDART00000092324
ENSDART00000179970
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr13_-_21701323 2.27 ENSDART00000164112
si:dkey-191g9.7
chr14_+_38786298 2.27 ENSDART00000164440
si:ch211-195b11.3
chr2_-_51096647 2.26 ENSDART00000167172
si:ch73-52e5.2
chr8_+_50983551 2.26 ENSDART00000142061
si:dkey-32e23.4
chr15_+_22311803 2.26 ENSDART00000150182
hepatic and glial cell adhesion molecule a
chr15_-_18138607 2.25 ENSDART00000176690

chr8_-_31716302 2.25 ENSDART00000061832
si:dkey-46a10.3
chr18_+_30028637 2.24 ENSDART00000139750
si:ch211-220f16.1
chr21_+_7131970 2.21 ENSDART00000161921
zgc:113019
chr21_+_13205859 2.21 ENSDART00000102253
spectrin alpha, non-erythrocytic 1

Network of associatons between targets according to the STRING database.

First level regulatory network of pax2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
2.1 6.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.4 4.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
1.3 3.9 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
1.3 3.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.3 5.0 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.2 4.9 GO:0034969 histone arginine methylation(GO:0034969)
1.1 3.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
1.1 3.2 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184)
1.0 3.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.0 18.9 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.9 2.8 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.9 2.8 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.9 2.7 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.9 2.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.9 5.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 3.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.8 3.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.8 2.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.8 4.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 2.3 GO:0015824 proline transport(GO:0015824)
0.7 10.5 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.7 3.7 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.7 5.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.7 4.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7 6.6 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.7 2.9 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.7 2.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.7 2.8 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.7 4.8 GO:0035627 ceramide transport(GO:0035627)
0.7 2.0 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.7 2.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.6 1.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 2.5 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.6 1.7 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.6 1.7 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.5 2.7 GO:0007412 axon target recognition(GO:0007412)
0.5 3.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.5 2.2 GO:0030091 protein repair(GO:0030091)
0.5 1.6 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.5 1.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.5 2.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.5 1.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 3.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.5 2.5 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.5 2.0 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.5 2.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.9 GO:0043476 pigment accumulation(GO:0043476)
0.5 1.9 GO:0021742 abducens nucleus development(GO:0021742)
0.5 1.4 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.5 1.9 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.5 1.9 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.5 1.9 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.5 2.8 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5 2.3 GO:0061072 iris morphogenesis(GO:0061072)
0.5 2.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 2.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.4 1.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.4 2.2 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.4 5.7 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 3.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 2.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.4 4.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 2.1 GO:1901207 regulation of heart looping(GO:1901207)
0.4 1.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.4 3.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.4 3.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 1.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 1.9 GO:0000012 single strand break repair(GO:0000012)
0.4 1.8 GO:0034505 tooth mineralization(GO:0034505)
0.4 1.5 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.4 1.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.4 2.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 1.8 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.3 1.0 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.3 2.1 GO:0006004 fucose metabolic process(GO:0006004)
0.3 5.4 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 1.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.3 3.6 GO:0051597 response to methylmercury(GO:0051597)
0.3 1.3 GO:0010039 response to iron ion(GO:0010039)
0.3 4.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 1.3 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.3 2.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 10.4 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.3 8.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 0.9 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 1.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 0.9 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 1.5 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.3 1.7 GO:0071800 podosome assembly(GO:0071800)
0.3 0.9 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.3 2.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 1.1 GO:0015677 copper ion import(GO:0015677)
0.3 1.4 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3 1.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3 3.3 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.3 1.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.3 13.0 GO:0030641 regulation of cellular pH(GO:0030641)
0.3 3.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.3 0.8 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.3 1.9 GO:0090398 cellular senescence(GO:0090398)
0.3 1.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 1.3 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 1.3 GO:0006013 mannose metabolic process(GO:0006013)
0.3 2.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.3 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 3.8 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.3 1.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 0.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 0.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.0 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 5.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.9 GO:0008343 adult feeding behavior(GO:0008343)
0.2 2.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.2 1.4 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.9 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 1.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 0.9 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 3.3 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.2 2.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.3 GO:0070293 renal absorption(GO:0070293)
0.2 1.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.6 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 0.9 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 1.3 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.2 0.8 GO:0071632 optomotor response(GO:0071632)
0.2 1.7 GO:0051013 microtubule severing(GO:0051013)
0.2 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.6 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 1.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 1.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 1.9 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.2 3.9 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.2 1.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.7 GO:0021855 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamus cell migration(GO:0021855) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.2 0.9 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 2.0 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.2 1.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 5.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.9 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.2 0.9 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 1.0 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 3.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 3.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 0.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 2.0 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.2 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 0.5 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 3.9 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.2 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.2 2.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.5 GO:0009099 valine biosynthetic process(GO:0009099)
0.2 1.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 1.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 4.0 GO:0048264 determination of ventral identity(GO:0048264)
0.2 1.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 0.5 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.2 1.2 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 0.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.5 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.7 GO:0043393 regulation of protein binding(GO:0043393)
0.1 0.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 3.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.3 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.9 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 2.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 8.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 2.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 4.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 4.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.1 GO:0046323 glucose import(GO:0046323)
0.1 1.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 2.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 3.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 3.4 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.3 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 4.0 GO:0016180 snRNA processing(GO:0016180)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 4.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 3.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.8 GO:0007041 lysosomal transport(GO:0007041)
0.1 1.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 2.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 6.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 3.5 GO:0015908 fatty acid transport(GO:0015908)
0.1 1.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.3 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.5 GO:1990402 embryonic liver development(GO:1990402)
0.1 1.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 2.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 2.0 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.6 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 3.6 GO:0001841 neural tube formation(GO:0001841)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 2.1 GO:0016233 telomere capping(GO:0016233)
0.1 1.8 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.1 2.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 4.4 GO:0030282 bone mineralization(GO:0030282)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.6 GO:0035476 angioblast cell migration(GO:0035476)
0.1 0.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 4.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 2.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 2.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.5 GO:0061709 reticulophagy(GO:0061709)
0.1 1.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.9 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 6.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.4 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.4 GO:0035989 tendon development(GO:0035989)
0.1 2.3 GO:0032456 endocytic recycling(GO:0032456)
0.1 4.0 GO:0007338 single fertilization(GO:0007338)
0.1 3.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 6.5 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 2.0 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.7 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.1 0.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 1.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.1 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.7 GO:0006096 glycolytic process(GO:0006096)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.1 2.0 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.3 GO:0006298 mismatch repair(GO:0006298)
0.1 3.7 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.1 0.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.8 GO:0043270 positive regulation of ion transport(GO:0043270)
0.1 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.9 GO:0045116 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.5 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 1.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 3.9 GO:0032880 regulation of protein localization(GO:0032880)
0.1 0.4 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 2.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 6.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.8 GO:0009411 response to UV(GO:0009411)
0.0 0.8 GO:0050821 protein stabilization(GO:0050821)
0.0 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 4.1 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.9 GO:0090148 membrane fission(GO:0090148)
0.0 1.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 2.3 GO:0051170 nuclear import(GO:0051170)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 4.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.9 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.4 GO:0046688 response to copper ion(GO:0046688)
0.0 1.2 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 2.6 GO:0048565 digestive tract development(GO:0048565)
0.0 1.0 GO:0001878 response to yeast(GO:0001878)
0.0 1.6 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 2.2 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.9 GO:0021986 habenula development(GO:0021986)
0.0 3.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.1 GO:0072657 protein localization to membrane(GO:0072657)
0.0 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 4.9 GO:0006869 lipid transport(GO:0006869)
0.0 1.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.2 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.6 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.8 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.4 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 1.6 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 6.2 GO:0006886 intracellular protein transport(GO:0006886)
0.0 3.1 GO:0060026 convergent extension(GO:0060026)
0.0 0.8 GO:0016197 endosomal transport(GO:0016197)
0.0 0.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.3 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.3 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.0 1.1 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 1.4 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.0 0.0 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.5 4.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.4 13.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
1.3 7.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
1.3 11.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.2 17.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.0 3.8 GO:0097255 R2TP complex(GO:0097255)
0.9 3.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.9 2.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.9 2.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 3.3 GO:0016600 flotillin complex(GO:0016600)
0.7 2.2 GO:0033268 node of Ranvier(GO:0033268)
0.7 2.1 GO:1990879 CST complex(GO:1990879)
0.6 3.7 GO:0016589 NURF complex(GO:0016589)
0.6 1.7 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.6 1.7 GO:0008352 katanin complex(GO:0008352)
0.5 1.6 GO:0032044 DSIF complex(GO:0032044)
0.5 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 2.5 GO:0070724 BMP receptor complex(GO:0070724)
0.5 7.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 1.6 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.4 1.6 GO:0043291 RAVE complex(GO:0043291)
0.4 1.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.4 1.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 4.8 GO:0000815 ESCRT III complex(GO:0000815)
0.3 1.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.5 GO:0035060 brahma complex(GO:0035060)
0.3 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.3 6.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.3 5.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 1.2 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 4.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 7.1 GO:0035371 microtubule plus-end(GO:0035371)
0.3 0.8 GO:0072380 TRC complex(GO:0072380)
0.3 1.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 1.0 GO:0098842 postsynaptic early endosome(GO:0098842)
0.3 6.1 GO:0071141 SMAD protein complex(GO:0071141)
0.2 2.5 GO:0005682 U5 snRNP(GO:0005682)
0.2 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 1.6 GO:0030897 HOPS complex(GO:0030897)
0.2 2.1 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 3.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2 0.6 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 1.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 1.9 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.7 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 4.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 1.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 1.6 GO:0005771 multivesicular body(GO:0005771)
0.2 1.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.7 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 18.9 GO:0005770 late endosome(GO:0005770)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.5 GO:0005948 acetolactate synthase complex(GO:0005948)
0.2 0.8 GO:0008091 spectrin(GO:0008091)
0.2 5.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.2 GO:0032797 SMN complex(GO:0032797)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 6.1 GO:0030426 growth cone(GO:0030426)
0.1 4.9 GO:0043204 perikaryon(GO:0043204)
0.1 0.4 GO:0042721 mitochondrial intermembrane space protein transporter complex(GO:0042719) mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.1 22.4 GO:0005764 lysosome(GO:0005764)
0.1 1.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 2.0 GO:0005903 brush border(GO:0005903)
0.1 9.1 GO:0031201 SNARE complex(GO:0031201)
0.1 13.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 4.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.8 GO:0032039 integrator complex(GO:0032039)
0.1 8.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 4.3 GO:0030141 secretory granule(GO:0030141)
0.1 2.9 GO:0005776 autophagosome(GO:0005776)
0.1 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.4 GO:0030496 midbody(GO:0030496)
0.1 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 6.1 GO:0005774 vacuolar membrane(GO:0005774)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 2.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.0 GO:0070461 SAGA-type complex(GO:0070461)
0.1 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 4.7 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.0 3.0 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.0 GO:0005871 kinesin complex(GO:0005871)
0.0 3.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.9 GO:0005768 endosome(GO:0005768)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 6.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 14.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 2.5 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.9 GO:0030133 transport vesicle(GO:0030133)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
2.1 8.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.1 6.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.6 4.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.4 4.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
1.3 5.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.2 3.6 GO:0047690 aspartyltransferase activity(GO:0047690)
1.0 4.2 GO:0030626 U12 snRNA binding(GO:0030626)
1.0 3.9 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
1.0 2.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
1.0 4.8 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
1.0 26.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.9 3.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.9 2.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.9 6.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.9 2.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.8 3.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.8 2.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8 4.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.7 2.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.7 2.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.7 4.2 GO:0043531 ADP binding(GO:0043531)
0.7 13.9 GO:0001671 ATPase activator activity(GO:0001671)
0.7 2.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.6 1.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.6 2.9 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.6 1.7 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.5 3.3 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 2.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.5 5.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.5 2.0 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.5 5.0 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.5 3.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 6.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 2.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.4 1.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.4 2.6 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.4 5.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 2.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.4 1.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 1.6 GO:0070513 death domain binding(GO:0070513)
0.4 1.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 2.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.4 2.0 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.4 5.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 1.9 GO:0060182 apelin receptor activity(GO:0060182)
0.4 1.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 3.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4 1.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.4 8.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 2.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.0 GO:0038046 enkephalin receptor activity(GO:0038046)
0.3 5.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.3 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.3 2.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 0.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 0.9 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 1.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 3.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 3.5 GO:0043495 protein anchor(GO:0043495)
0.3 1.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.8 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.3 3.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 2.2 GO:0015232 heme transporter activity(GO:0015232)
0.3 1.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 8.3 GO:0030165 PDZ domain binding(GO:0030165)
0.3 3.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 6.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 0.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.0 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 2.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 5.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.9 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.2 4.0 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 2.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 3.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.6 GO:0005035 death receptor activity(GO:0005035)
0.2 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 7.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 3.1 GO:0008061 chitin binding(GO:0008061)
0.2 1.7 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 1.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 1.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 2.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 3.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 2.7 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.2 1.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 2.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 1.3 GO:0019809 spermidine binding(GO:0019809)
0.2 0.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 4.9 GO:0015248 sterol transporter activity(GO:0015248)
0.2 1.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 2.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 1.9 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 2.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 5.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 0.5 GO:0003984 acetolactate synthase activity(GO:0003984)
0.2 1.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 3.3 GO:0008143 poly(A) binding(GO:0008143)
0.2 2.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 1.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.9 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 4.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 5.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 5.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 1.5 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 5.0 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.5 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 4.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 4.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 5.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.6 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.1 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.1 5.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 4.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.0 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.1 1.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 1.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 4.2 GO:0044325 ion channel binding(GO:0044325)
0.1 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 3.9 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 2.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 4.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 4.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 8.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.9 GO:0017022 myosin binding(GO:0017022)
0.1 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 3.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 4.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 2.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 3.6 GO:0060090 binding, bridging(GO:0060090)
0.0 11.6 GO:0003924 GTPase activity(GO:0003924)
0.0 3.6 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.2 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 6.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 2.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 4.9 GO:0005543 phospholipid binding(GO:0005543)
0.0 2.2 GO:0016874 ligase activity(GO:0016874)
0.0 1.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0046332 SMAD binding(GO:0046332)
0.0 5.4 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 6.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 11.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 3.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 3.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 4.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.1 PID MYC PATHWAY C-MYC pathway
0.1 4.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 3.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 3.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.7 PID E2F PATHWAY E2F transcription factor network
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.6 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.4 PID ATR PATHWAY ATR signaling pathway
0.1 4.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.3 14.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.6 2.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 6.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.5 4.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5 9.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.5 6.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 6.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.4 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 1.6 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.4 7.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 3.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 2.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 6.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 5.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 10.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 3.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 2.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 1.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.2 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 2.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 2.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 3.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 2.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 4.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.6 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.2 2.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 2.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 5.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 2.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 8.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 3.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 3.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase