Project
PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
Navigation
Downloads
Results for pax2b
Z-value: 1.56
Motif logo
Transcription factors associated with pax2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pax2b | dr11_v1_chr12_-_45876387_45876387 | 0.39 | 1.1e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_10720294 Show fit | 10.70 |
ENSDART00000139387
|
ATPase Na+/K+ transporting subunit beta 1b |
|
| chr16_-_45069882 Show fit | 8.56 |
ENSDART00000058384
|
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
|
| chr11_+_25112269 Show fit | 7.73 |
ENSDART00000147546
|
ndrg family member 3a |
|
| chr22_-_11136625 Show fit | 7.30 |
ENSDART00000016873
ENSDART00000125561 |
ATPase H+ transporting accessory protein 2 |
|
| chr2_-_38000276 Show fit | 7.08 |
ENSDART00000034790
|
Purkinje cell protein 4 like 1 |
|
| chr7_+_38770167 Show fit | 6.91 |
ENSDART00000190827
|
Rho GTPase activating protein 1 |
|
| chr24_-_7632187 Show fit | 6.73 |
ENSDART00000041714
|
ATPase H+ transporting V0 subunit a1b |
|
| chr7_-_42206720 Show fit | 6.50 |
ENSDART00000110907
|
integrin alpha FG-GAP repeat containing 1 |
|
| chr23_-_4915118 Show fit | 6.37 |
ENSDART00000060714
|
ATPase H+ transporting accessory protein 1a |
|
| chr24_-_17023392 Show fit | 6.36 |
ENSDART00000106058
|
prostaglandin D2 synthase b, tandem duplicate 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pax2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 18.9 | GO:0071436 | cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436) |
| 0.3 | 13.0 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.7 | 10.5 | GO:0045851 | vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
| 0.3 | 10.4 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
| 0.1 | 8.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.3 | 8.2 | GO:0035622 | intrahepatic bile duct development(GO:0035622) |
| 2.3 | 6.9 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831) |
| 0.7 | 6.6 | GO:1902868 | positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) |
| 0.1 | 6.5 | GO:0007269 | neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643) |
| 2.1 | 6.4 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.4 | GO:0005764 | lysosome(GO:0005764) |
| 0.2 | 18.9 | GO:0005770 | late endosome(GO:0005770) |
| 1.2 | 17.1 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 14.4 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 1.4 | 13.9 | GO:0090533 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.1 | 13.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 1.3 | 11.3 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.1 | 9.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 8.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 1.3 | 7.9 | GO:0033181 | plasma membrane proton-transporting V-type ATPase complex(GO:0033181) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 26.9 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.7 | 13.9 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 11.6 | GO:0003924 | GTPase activity(GO:0003924) |
| 2.1 | 8.6 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.3 | 8.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.4 | 8.1 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 8.1 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.2 | 7.9 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 2.3 | 6.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 2.1 | 6.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.1 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.3 | 6.6 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 6.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.6 | 4.8 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 4.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 4.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 4.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 4.1 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 4.1 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 4.1 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 14.1 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.3 | 10.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.5 | 9.6 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 8.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.4 | 7.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.4 | 6.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.3 | 6.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.5 | 6.4 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.5 | 6.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 1.6 | 6.2 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |