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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pax2a+pax5

Z-value: 2.87

Motif logo

Transcription factors associated with pax2a+pax5

Gene Symbol Gene ID Gene Info
ENSDARG00000028148 paired box 2a
ENSDARG00000037383 paired box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax2adr11_v1_chr13_+_29773153_297731530.495.6e-07Click!
pax5dr11_v1_chr1_+_21731382_217313820.364.3e-04Click!

Activity profile of pax2a+pax5 motif

Sorted Z-values of pax2a+pax5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_29952169 63.05 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
alpha-tropomyosin
chr7_+_29951997 61.01 ENSDART00000173453
alpha-tropomyosin
chr7_+_29952719 40.49 ENSDART00000173737
alpha-tropomyosin
chr7_+_29955368 28.90 ENSDART00000173686
alpha-tropomyosin
chr3_-_61205711 27.64 ENSDART00000055062
parvalbumin 1
chr9_-_12034444 27.27 ENSDART00000038651
zinc finger protein 804A
chr24_-_40731305 23.98 ENSDART00000172073

chr12_+_13256415 23.52 ENSDART00000144542
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr3_-_46818001 20.15 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr25_+_33192796 19.41 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
zgc:171719
chr13_-_226109 18.91 ENSDART00000161705
ENSDART00000172744
ENSDART00000163902
ENSDART00000158208
reticulon 4b
chr5_+_36974931 17.89 ENSDART00000193063
gap junction protein delta 1a
chr14_+_50770537 17.83 ENSDART00000158723
synuclein, beta
chr3_+_32526799 17.47 ENSDART00000185755
si:ch73-367p23.2
chr13_-_9318891 17.32 ENSDART00000137364
si:dkey-33c12.3
chr16_-_27628994 17.12 ENSDART00000157407
NAC alpha domain containing
chr5_-_36837846 16.76 ENSDART00000032481
creatine kinase, muscle a
chr14_-_36378494 16.44 ENSDART00000058503
glycoprotein M6Aa
chr25_+_6306885 16.09 ENSDART00000142705
ENSDART00000067510
cellular retinoic acid binding protein 1a
chr14_+_22172047 15.56 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr18_+_9635178 15.08 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr11_-_44543082 14.96 ENSDART00000099568
G protein-coupled receptor 137Bb
chr21_+_19008168 14.77 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
neurofilament, light polypeptide a
chr9_-_42989297 14.44 ENSDART00000126871
titin, tandem duplicate 2
chr6_-_32703317 13.98 ENSDART00000064833
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr1_-_29045426 13.45 ENSDART00000019770
glycoprotein M6Ba
chr3_-_28250722 13.37 ENSDART00000165936
RNA binding fox-1 homolog 1
chr7_+_30787903 13.33 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr2_+_30916188 13.26 ENSDART00000137012
myomesin 1a (skelemin)
chr17_-_15528597 13.25 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr3_+_39566999 13.24 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr9_+_38962017 13.19 ENSDART00000140436
microtubule-associated protein 2
chr11_-_45171139 13.13 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr12_-_35787801 12.82 ENSDART00000171682
apoptosis-associated tyrosine kinase b
chr2_-_9646857 12.73 ENSDART00000056901
zgc:153615
chr21_+_21374277 12.57 ENSDART00000079431
reticulon 2b
chr2_-_44283554 12.55 ENSDART00000184684
myelin protein zero
chr8_-_1051438 12.51 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr1_+_14283692 12.43 ENSDART00000017679
protein phosphatase 2, regulatory subunit B, gamma a
chr9_-_7539297 12.30 ENSDART00000081550
ENSDART00000081553
desmin a
chr3_-_46817838 12.28 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr5_-_57641257 12.20 ENSDART00000149282
heat shock protein, alpha-crystallin-related, b2
chr23_-_1557195 12.11 ENSDART00000136436
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr3_-_28258462 11.95 ENSDART00000191573
RNA binding fox-1 homolog 1
chr19_-_103289 11.90 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr16_-_2818170 11.89 ENSDART00000081918
acyl-CoA thioesterase 22
chr9_+_23900703 11.86 ENSDART00000127859
tripartite motif containing 63b
chr9_+_40939336 11.36 ENSDART00000100386
myostatin b
chr10_-_17103651 11.33 ENSDART00000108959
ring finger protein 208
chr24_-_40668208 11.30 ENSDART00000171543
slow myosin heavy chain 1
chr13_-_31452516 11.21 ENSDART00000193268
reticulon 1a
chr16_-_43025885 11.21 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr19_-_9472893 11.00 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr3_-_22212764 10.98 ENSDART00000155490
microtubule-associated protein tau b
chr19_-_3240605 10.78 ENSDART00000105168
si:ch211-133n4.4
chr2_+_31833997 10.69 ENSDART00000066788
ependymin related 1
chr9_+_41612642 10.64 ENSDART00000138473
SPEG complex locus b
chr15_-_16098531 10.55 ENSDART00000080377
aldolase C, fructose-bisphosphate, a
chr5_+_38276582 10.49 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr25_-_225964 10.48 ENSDART00000193424

chr11_+_11201096 10.48 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr9_+_35901554 10.46 ENSDART00000005086
ATPase Na+/K+ transporting subunit alpha 1b
chr5_-_55395964 10.45 ENSDART00000145791
prune homolog 2 (Drosophila)
chr9_+_42066030 10.32 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr12_-_19103490 10.29 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr7_-_56793739 10.27 ENSDART00000082842
si:ch211-146m13.3
chr5_-_68916623 10.27 ENSDART00000141917
ENSDART00000109053
ankyrin 1, erythrocytic a
chr11_-_103136 10.24 ENSDART00000173308
ENSDART00000162982
engulfment and cell motility 2
chr6_-_14139503 10.19 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr18_+_1615 10.07 ENSDART00000082450
homer scaffolding protein 2
chr8_+_48603398 9.83 ENSDART00000074900
zgc:195023
chr4_+_26628822 9.80 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
IQ motif and Sec7 domain 3a
chr1_-_21409877 9.68 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr21_-_27010796 9.63 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr16_+_39146696 9.56 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr10_+_33171501 9.56 ENSDART00000159666
myosin, light chain 10, regulatory
chr3_-_12187245 9.53 ENSDART00000189553
ENSDART00000165131
sarcalumenin
chr8_-_23416362 9.42 ENSDART00000063005
G protein-coupled receptor 173
chr17_+_26569601 9.34 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr16_-_13730152 9.32 ENSDART00000138772
tweety family member 1
chr11_-_11625630 9.27 ENSDART00000161821
ENSDART00000193152
si:dkey-28e7.3
chr8_-_21268303 9.22 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr4_-_2162688 9.20 ENSDART00000148900
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr16_+_5196226 9.19 ENSDART00000189704
SOGA family member 3a
chr19_+_31771270 9.18 ENSDART00000147474
stathmin 2b
chr19_+_206835 9.16 ENSDART00000161137
sodium channel, voltage-gated, type I, beta b
chr6_-_13187168 9.07 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr19_-_12145390 8.99 ENSDART00000143087
poly A binding protein, cytoplasmic 1 b
chr23_+_40461411 8.97 ENSDART00000184223
SOGA family member 3b
chr18_+_402048 8.97 ENSDART00000166345
glucose-6-phosphate isomerase b
chr14_+_6991142 8.92 ENSDART00000157635
ENSDART00000059918
heterogeneous nuclear ribonucleoprotein H1
chr2_-_42864472 8.91 ENSDART00000134139
adenylate cyclase 8 (brain)
chr20_-_53981626 8.82 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr8_+_31248917 8.80 ENSDART00000112170
un-named hu7912
chr15_+_5923851 8.71 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
SH3 domain binding glutamate-rich protein
chr9_+_54679221 8.69 ENSDART00000167769
EGF-like-domain, multiple 6
chr5_-_28625515 8.68 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr5_-_31904562 8.66 ENSDART00000140640
coronin, actin binding protein, 1Cb
chr11_-_37509001 8.62 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr7_+_59020972 8.56 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr9_+_307863 8.54 ENSDART00000163474
SH3 and cysteine rich domain 3
chr21_-_21373242 8.51 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr11_-_18800299 8.44 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr22_+_18389271 8.42 ENSDART00000088270
YjeF N-terminal domain containing 3
chr6_+_52790049 8.41 ENSDART00000002571
matrilin 4
chr7_+_60551133 8.38 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr6_+_27146671 8.36 ENSDART00000156792
kinesin family member 1Aa
chr20_-_34868814 8.32 ENSDART00000153049
stathmin-like 4
chr1_-_14332283 8.30 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr14_+_25816874 8.30 ENSDART00000005499
glycine receptor, alpha 1
chr11_-_18799827 8.28 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr12_-_41684729 8.22 ENSDART00000184461
Janus kinase and microtubule interacting protein 3
chr14_+_25817246 8.17 ENSDART00000136733
glycine receptor, alpha 1
chr3_-_22191132 8.14 ENSDART00000154226
ENSDART00000155528
ENSDART00000155190
microtubule-associated protein tau b
chr5_-_55395384 8.12 ENSDART00000147298
ENSDART00000082577
prune homolog 2 (Drosophila)
chr16_+_41873708 8.02 ENSDART00000084631
ENSDART00000084639
ENSDART00000058611
sodium channel, voltage-gated, type I, beta a
chr20_-_54377933 8.00 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr19_-_31035155 8.00 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr24_+_35947077 7.95 ENSDART00000173406
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr5_+_37903790 7.84 ENSDART00000162470
transmembrane protease, serine 4b
chr16_-_18652646 7.81 ENSDART00000131438
formin homology 2 domain containing 3b
chr23_-_29376859 7.76 ENSDART00000146411
somatostatin 6
chr19_-_9662958 7.54 ENSDART00000041094
chloride channel, voltage-sensitive 1a
chr19_+_10396042 7.54 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr8_+_23165749 7.53 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr3_-_24980067 7.49 ENSDART00000048871
desumoylating isopeptidase 1a
chr23_-_23256726 7.47 ENSDART00000131353
si:dkey-98j1.5
chr19_-_25113660 7.47 ENSDART00000035538
protein tyrosine phosphatase type IVA, member 3
chr25_+_21324588 7.46 ENSDART00000151842
leucine rich repeat neuronal 3a
chr23_+_40460333 7.42 ENSDART00000184658
SOGA family member 3b
chr13_+_4405282 7.34 ENSDART00000148280
proline rich 18
chr11_-_11625369 7.34 ENSDART00000112328
si:dkey-28e7.3
chr4_+_21129752 7.33 ENSDART00000169764
synaptotagmin Ia
chr5_-_52277643 7.32 ENSDART00000010757
repulsive guidance molecule family member b
chr20_+_20499869 7.30 ENSDART00000036124
SIX homeobox 1b
chr16_+_29043813 7.30 ENSDART00000122681
nestin
chr5_-_22501663 7.25 ENSDART00000133174
si:dkey-27p18.5
chr25_+_14017609 7.24 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_+_18965750 7.22 ENSDART00000132379
LIM and calponin homology domains 1a
chr16_-_13516745 7.21 ENSDART00000145410
si:dkeyp-69b9.3
chr19_-_12145765 7.20 ENSDART00000032474
poly A binding protein, cytoplasmic 1 b
chr25_+_34984333 7.17 ENSDART00000154760
coiled-coil domain containing 136b
chr7_-_23996133 7.16 ENSDART00000173761
si:dkey-183c6.8
chr1_+_54908895 7.15 ENSDART00000145652
golgin A7 family, member Ba
chr9_-_31278048 7.12 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr20_-_19422496 7.11 ENSDART00000143658
si:ch211-278j3.3
chr3_+_26081343 7.10 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr19_-_31035325 7.07 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr2_-_32558795 7.01 ENSDART00000140026
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr16_+_32559821 7.00 ENSDART00000093250
POU class 3 homeobox 2b
chr23_-_19686791 7.00 ENSDART00000161973
zgc:193598
chr7_-_49594995 6.97 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr17_-_8976307 6.96 ENSDART00000092113
zinc finger, RAN-binding domain containing 1b
chr4_-_8882572 6.90 ENSDART00000190060
metallophosphoesterase domain containing 1
chr21_+_103194 6.79 ENSDART00000162755
zyg-11 related, cell cycle regulator
chr13_-_29424454 6.75 ENSDART00000026765
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr16_-_24518027 6.74 ENSDART00000134120
ENSDART00000143761
cell adhesion molecule 4
chr5_-_68916455 6.74 ENSDART00000171465
ankyrin 1, erythrocytic a
chr21_+_5209716 6.73 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr24_-_11127493 6.71 ENSDART00000144066
myosin VIIA and Rab interacting protein
chr23_+_45579497 6.70 ENSDART00000110381
early growth response 4
chr18_-_6633984 6.70 ENSDART00000185241
troponin I, skeletal, slow c
chr23_-_26522760 6.69 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
chr9_-_7421135 6.66 ENSDART00000144600
bridging integrator 1a
chr17_+_23938283 6.62 ENSDART00000184391
si:ch211-189k9.2
chr25_-_7520937 6.62 ENSDART00000170050
cyclin-dependent kinase inhibitor 1Cb
chr9_-_49493305 6.60 ENSDART00000148707
ENSDART00000148561
xin actin binding repeat containing 2b
chr10_-_35542071 6.59 ENSDART00000162139
si:ch211-244c8.4
chr20_-_35040041 6.57 ENSDART00000131919
kinesin family member 26Bb
chr17_-_26911852 6.56 ENSDART00000045842
regulator of calcineurin 3
chr11_-_43473824 6.55 ENSDART00000179561
transmembrane protein 63Bb
chr7_+_1467863 6.54 ENSDART00000173433
ER membrane protein complex subunit 4
chr23_+_37323962 6.53 ENSDART00000102881
family with sequence similarity 43, member B
chr20_+_19238382 6.47 ENSDART00000136757
fibronectin type III domain containing 4a
chr19_-_21716593 6.40 ENSDART00000155126
zinc finger protein 516
chr5_-_69041102 6.35 ENSDART00000161561
ankyrin 1, erythrocytic a
chr17_-_22010668 6.34 ENSDART00000031998
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr9_+_17787864 6.31 ENSDART00000013111
diacylglycerol kinase, eta
chr7_+_5920665 6.29 ENSDART00000173208
si:dkey-23a13.11
chr23_+_4299887 6.29 ENSDART00000132604
l(3)mbt-like 1a (Drosophila)
chr19_-_32783373 6.27 ENSDART00000145790
5'-nucleotidase, cytosolic IAa
chr18_-_42172101 6.23 ENSDART00000124211
contactin 5
chr14_-_2285955 6.23 ENSDART00000183928
protocadherin 2 alpha b 9
chr18_-_6634424 6.23 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr15_+_6109861 6.21 ENSDART00000185154
Purkinje cell protein 4
chr23_-_29502287 6.20 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr22_-_14161309 6.18 ENSDART00000133365
si:ch211-246m6.5
chr14_+_21783229 6.17 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr10_-_32920690 6.17 ENSDART00000136245
cut-like homeobox 1a
chr6_-_39764995 6.14 ENSDART00000085277
phosphofructokinase, muscle b
chr1_-_10885269 6.12 ENSDART00000126518
ENSDART00000009886
dystrophin
chr11_+_23957440 6.11 ENSDART00000190721
contactin 2
chr4_-_1360495 6.06 ENSDART00000164623
pleiotrophin
chr16_+_28596555 6.06 ENSDART00000046209
ENSDART00000141708
acyl-CoA binding domain containing 7
chr2_-_4494239 6.06 ENSDART00000191702
adiponectin, C1Q and collagen domain containing, b
chr18_+_10689772 6.03 ENSDART00000126441
leptin a
chr2_-_21335131 6.02 ENSDART00000057022
kelch-like family member 40a
chr13_+_27951688 6.01 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr11_+_40649412 6.00 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr25_-_13842618 5.99 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of pax2a+pax5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0071361 cellular response to ethanol(GO:0071361)
5.0 15.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
4.7 18.9 GO:0021557 oculomotor nerve development(GO:0021557)
4.5 13.5 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
4.3 21.3 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
3.6 10.7 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
3.1 30.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
3.1 12.3 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
3.0 11.9 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
2.9 8.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
2.9 17.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
2.8 16.6 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
2.8 11.0 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
2.4 7.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
2.4 9.6 GO:0060074 synapse maturation(GO:0060074)
2.3 6.8 GO:0042908 xenobiotic transport(GO:0042908)
2.2 23.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.1 12.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
2.1 12.7 GO:0035332 positive regulation of hippo signaling(GO:0035332)
2.1 8.4 GO:0010874 regulation of cholesterol efflux(GO:0010874)
2.1 4.2 GO:0006110 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
2.1 6.2 GO:0048917 posterior lateral line ganglion development(GO:0048917)
2.0 6.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
2.0 6.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
2.0 6.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
2.0 15.9 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.9 5.6 GO:0097264 self proteolysis(GO:0097264)
1.8 7.3 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
1.8 187.9 GO:0061515 myeloid cell development(GO:0061515)
1.8 17.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.8 7.1 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
1.8 5.3 GO:0035989 tendon development(GO:0035989)
1.8 8.8 GO:0046677 response to antibiotic(GO:0046677)
1.7 8.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) positive regulation of voltage-gated calcium channel activity(GO:1901387) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
1.7 18.6 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
1.7 6.7 GO:1903589 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
1.7 13.2 GO:0034334 adherens junction maintenance(GO:0034334)
1.6 4.7 GO:0021961 posterior commissure morphogenesis(GO:0021961)
1.5 4.6 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.5 4.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
1.5 4.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
1.5 8.7 GO:0003232 bulbus arteriosus development(GO:0003232)
1.4 7.2 GO:0051145 smooth muscle cell differentiation(GO:0051145)
1.4 33.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.4 7.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.3 16.8 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.3 5.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
1.3 13.8 GO:0048769 sarcomerogenesis(GO:0048769)
1.2 4.8 GO:0003322 pancreatic A cell development(GO:0003322)
1.2 4.8 GO:0007638 mechanosensory behavior(GO:0007638)
1.2 4.7 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
1.2 4.7 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
1.1 19.8 GO:0016203 muscle attachment(GO:0016203)
1.1 4.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
1.1 8.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.0 14.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.0 7.0 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
1.0 5.0 GO:0035988 chondrocyte proliferation(GO:0035988)
1.0 2.9 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.0 5.8 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.9 6.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.9 6.6 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.9 1.9 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.9 16.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.9 7.9 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.9 7.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.9 3.4 GO:0051012 microtubule sliding(GO:0051012)
0.8 4.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.8 12.6 GO:0035108 limb morphogenesis(GO:0035108)
0.8 2.5 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.8 7.4 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.8 2.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.8 32.2 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.8 14.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 2.3 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.7 17.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.7 5.9 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.7 10.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.7 2.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.7 3.4 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7 6.7 GO:0060612 adipose tissue development(GO:0060612)
0.7 5.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.7 2.0 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) eurydendroid cell differentiation(GO:0021755) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.7 8.0 GO:0021592 fourth ventricle development(GO:0021592)
0.7 4.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.6 3.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 8.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.6 4.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.6 5.7 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.6 3.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.6 9.7 GO:0048899 anterior lateral line development(GO:0048899)
0.6 2.3 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.6 5.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.6 2.9 GO:0071072 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.6 1.7 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.6 3.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.6 6.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.6 7.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.6 10.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.5 3.8 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.5 15.9 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.5 2.7 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.5 2.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 3.7 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.5 3.7 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.5 5.8 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.5 6.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.5 2.0 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.5 11.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.5 6.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 1.4 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.5 5.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.5 3.8 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.5 0.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.5 8.0 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.5 3.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968) postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.5 6.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5 0.9 GO:0090190 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.5 7.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.4 20.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 10.3 GO:0051639 actin filament network formation(GO:0051639)
0.4 3.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.4 2.5 GO:0055016 hypochord development(GO:0055016)
0.4 15.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 8.0 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.4 18.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.9 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 9.0 GO:0006094 gluconeogenesis(GO:0006094)
0.4 3.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 3.2 GO:0034333 adherens junction assembly(GO:0034333)
0.4 1.4 GO:0090299 regulation of neural crest formation(GO:0090299)
0.4 7.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 7.7 GO:0006491 N-glycan processing(GO:0006491)
0.3 11.4 GO:0031103 axon regeneration(GO:0031103)
0.3 5.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 4.8 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.3 16.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.3 9.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 11.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 3.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 4.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 4.9 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 2.6 GO:0070293 renal absorption(GO:0070293)
0.3 1.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 7.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.3 5.3 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 2.4 GO:0032196 transposition(GO:0032196)
0.3 10.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 7.5 GO:0030497 fatty acid elongation(GO:0030497)
0.3 1.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 2.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.3 2.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.3 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 6.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.3 1.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304) negative regulation of fatty acid metabolic process(GO:0045922)
0.3 0.8 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.3 3.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.3 2.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 10.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 1.1 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.3 2.4 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 1.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 12.7 GO:0006612 protein targeting to membrane(GO:0006612)
0.3 6.4 GO:0070831 basement membrane assembly(GO:0070831)
0.3 2.6 GO:0060035 notochord cell development(GO:0060035)
0.3 4.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 3.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 5.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 3.6 GO:0043248 proteasome assembly(GO:0043248)
0.2 4.5 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.2 3.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 2.3 GO:0003139 secondary heart field specification(GO:0003139)
0.2 3.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 4.9 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 1.4 GO:0090342 regulation of cell aging(GO:0090342)
0.2 5.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 3.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 1.8 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 1.4 GO:0030242 pexophagy(GO:0030242)
0.2 3.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.9 GO:0044241 lipid digestion(GO:0044241)
0.2 2.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 9.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 10.9 GO:0007416 synapse assembly(GO:0007416)
0.2 1.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 18.3 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.2 13.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 1.7 GO:0021794 thalamus development(GO:0021794)
0.2 0.4 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.2 3.8 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.2 4.4 GO:0007020 microtubule nucleation(GO:0007020)
0.2 2.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 0.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 2.1 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.2 0.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.2 6.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.2 1.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 30.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 24.1 GO:0051260 protein homooligomerization(GO:0051260)
0.2 0.6 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.2 3.3 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.2 2.0 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.2 2.0 GO:0099587 sodium ion import(GO:0097369) inorganic cation import into cell(GO:0098659) sodium ion import across plasma membrane(GO:0098719) inorganic ion import into cell(GO:0099587) sodium ion import into cell(GO:1990118)
0.2 2.9 GO:0008354 germ cell migration(GO:0008354)
0.2 2.7 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.2 1.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 2.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 32.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.7 GO:0070475 rRNA base methylation(GO:0070475)
0.2 7.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.2 3.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 4.0 GO:0071174 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.2 8.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 1.8 GO:0046661 male sex differentiation(GO:0046661)
0.2 1.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.2 7.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 1.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 1.8 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.2 1.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 3.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 1.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 0.6 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2 1.1 GO:0045907 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460) positive regulation of vasoconstriction(GO:0045907)
0.2 1.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 0.8 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.2 0.2 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.1 2.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 3.4 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 4.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.6 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 7.0 GO:0048484 enteric nervous system development(GO:0048484)
0.1 10.2 GO:0055088 lipid homeostasis(GO:0055088)
0.1 1.2 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 2.9 GO:0002068 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.1 2.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 4.5 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 4.0 GO:0060037 pharyngeal system development(GO:0060037)
0.1 2.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 4.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 2.2 GO:0018158 protein oxidation(GO:0018158)
0.1 2.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 7.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 0.4 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 2.4 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.1 14.2 GO:0010506 regulation of autophagy(GO:0010506)
0.1 0.7 GO:0031646 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.1 1.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.1 2.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 1.2 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.0 GO:0007254 JNK cascade(GO:0007254)
0.1 1.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0090075 relaxation of muscle(GO:0090075)
0.1 10.0 GO:0006936 muscle contraction(GO:0006936)
0.1 1.7 GO:0042026 protein refolding(GO:0042026)
0.1 9.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.0 GO:1901998 toxin transport(GO:1901998)
0.1 0.2 GO:0046324 regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324)
0.1 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.6 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 4.2 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284) S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498) S-adenosylmethionine metabolic process(GO:0046500)
0.1 2.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 30.9 GO:0050767 regulation of neurogenesis(GO:0050767)
0.1 1.0 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 3.7 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.1 2.7 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.1 6.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 3.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 2.1 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 1.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.9 GO:0046549 retinal cone cell development(GO:0046549)
0.1 4.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 4.6 GO:0031101 fin regeneration(GO:0031101)
0.1 5.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.4 GO:0048854 brain morphogenesis(GO:0048854)
0.1 1.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 8.3 GO:0006821 chloride transport(GO:0006821)
0.1 2.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.1 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.9 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 3.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 4.8 GO:0014032 neural crest cell development(GO:0014032)
0.1 1.0 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 2.6 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 2.2 GO:0006282 regulation of DNA repair(GO:0006282)
0.1 0.5 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 2.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 2.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.6 GO:0035094 response to nicotine(GO:0035094)
0.1 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 4.1 GO:1901342 regulation of vasculature development(GO:1901342)
0.1 1.3 GO:0048675 axon extension(GO:0048675)
0.0 7.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 3.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 2.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.3 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 2.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 1.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.6 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.4 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.9 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 4.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.5 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.7 GO:0021782 glial cell development(GO:0021782)
0.0 9.6 GO:0031175 neuron projection development(GO:0031175)
0.0 0.3 GO:0060840 artery development(GO:0060840)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 7.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 3.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 6.5 GO:0006897 endocytosis(GO:0006897)
0.0 3.8 GO:0098916 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 3.0 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 9.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.1 30.9 GO:0098982 GABA-ergic synapse(GO:0098982)
2.9 17.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
2.7 56.2 GO:0031430 M band(GO:0031430)
2.4 7.2 GO:0033268 node of Ranvier(GO:0033268)
2.3 9.2 GO:0016460 myosin II complex(GO:0016460)
1.9 5.8 GO:0060077 inhibitory synapse(GO:0060077)
1.8 7.1 GO:0031673 H zone(GO:0031673)
1.8 8.8 GO:0042584 chromaffin granule membrane(GO:0042584)
1.6 18.7 GO:0044295 axonal growth cone(GO:0044295)
1.5 27.7 GO:0043209 myelin sheath(GO:0043209)
1.5 180.0 GO:0005884 actin filament(GO:0005884)
1.5 6.0 GO:0031672 A band(GO:0031672)
1.5 4.5 GO:0032839 dendrite cytoplasm(GO:0032839)
1.4 8.6 GO:0005784 Sec61 translocon complex(GO:0005784)
1.4 29.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.3 5.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.3 16.6 GO:0005922 connexon complex(GO:0005922)
1.3 3.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.1 2.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.9 6.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.9 9.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.9 15.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.9 3.4 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.8 25.1 GO:0031594 neuromuscular junction(GO:0031594)
0.8 2.4 GO:0034515 proteasome storage granule(GO:0034515)
0.8 5.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.7 10.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.7 11.3 GO:0030315 T-tubule(GO:0030315)
0.7 15.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.6 4.4 GO:0005921 gap junction(GO:0005921)
0.6 20.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 59.5 GO:0043025 neuronal cell body(GO:0043025)
0.6 5.0 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.6 2.5 GO:0060171 stereocilium membrane(GO:0060171)
0.6 6.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.6 2.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.6 5.9 GO:0045171 intercellular bridge(GO:0045171)
0.5 55.6 GO:0005882 intermediate filament(GO:0005882)
0.5 2.0 GO:0005903 brush border(GO:0005903)
0.5 6.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 7.1 GO:0071564 npBAF complex(GO:0071564)
0.4 2.2 GO:0097224 sperm connecting piece(GO:0097224)
0.4 3.5 GO:0001772 immunological synapse(GO:0001772)
0.4 5.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 22.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 7.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 5.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 4.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 12.5 GO:0030426 growth cone(GO:0030426)
0.3 3.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 3.6 GO:0008180 COP9 signalosome(GO:0008180)
0.3 5.4 GO:0015030 Cajal body(GO:0015030)
0.3 5.9 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.3 7.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 4.9 GO:0031209 SCAR complex(GO:0031209)
0.3 0.9 GO:1990745 EARP complex(GO:1990745)
0.3 1.8 GO:0031526 brush border membrane(GO:0031526)
0.3 11.3 GO:0032432 actin filament bundle(GO:0032432)
0.3 11.2 GO:0031225 anchored component of membrane(GO:0031225)
0.3 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 10.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 1.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 4.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 3.3 GO:0036157 outer dynein arm(GO:0036157)
0.3 1.9 GO:0030914 STAGA complex(GO:0030914)
0.3 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 1.8 GO:0000439 core TFIIH complex(GO:0000439)
0.3 14.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 11.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 18.7 GO:0005814 centriole(GO:0005814)
0.2 10.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 8.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.2 19.5 GO:0005871 kinesin complex(GO:0005871)
0.2 5.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 3.6 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 4.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 1.6 GO:0072487 MSL complex(GO:0072487)
0.2 1.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.6 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 4.4 GO:0046930 pore complex(GO:0046930)
0.2 34.0 GO:0070382 exocytic vesicle(GO:0070382)
0.2 0.9 GO:0097060 synaptic membrane(GO:0097060)
0.2 10.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 11.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 31.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 11.6 GO:0031201 SNARE complex(GO:0031201)
0.2 4.1 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.2 0.5 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 2.0 GO:0000815 ESCRT III complex(GO:0000815)
0.2 3.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 62.9 GO:0043005 neuron projection(GO:0043005)
0.1 3.0 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.9 GO:0031674 I band(GO:0031674)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 10.8 GO:0005581 collagen trimer(GO:0005581)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 6.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 7.4 GO:0001726 ruffle(GO:0001726)
0.1 3.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 8.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 3.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 4.5 GO:0099572 postsynaptic specialization(GO:0099572)
0.1 2.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.5 GO:0036126 sperm flagellum(GO:0036126)
0.1 0.2 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 5.3 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 8.6 GO:0005770 late endosome(GO:0005770)
0.1 1.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 21.7 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.1 4.8 GO:0000776 kinetochore(GO:0000776)
0.1 9.9 GO:0045202 synapse(GO:0045202)
0.1 1.4 GO:0030027 lamellipodium(GO:0030027)
0.1 2.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 14.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 13.3 GO:0030054 cell junction(GO:0030054)
0.0 0.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 28.7 GO:0005856 cytoskeleton(GO:0005856)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 99.9 GO:0005634 nucleus(GO:0005634)
0.0 14.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.4 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.8 GO:1903136 cuprous ion binding(GO:1903136)
3.0 23.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.6 7.8 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
2.6 15.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.4 12.1 GO:2001070 starch binding(GO:2001070)
2.3 9.2 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
2.2 19.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
2.1 17.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.1 8.6 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
2.0 16.1 GO:0001972 retinoic acid binding(GO:0001972)
1.9 32.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.8 5.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.7 30.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
1.7 18.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
1.7 5.0 GO:0031704 apelin receptor binding(GO:0031704)
1.6 4.8 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
1.5 7.7 GO:0060182 apelin receptor activity(GO:0060182)
1.5 4.6 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.5 6.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.4 8.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 186.8 GO:0042803 protein homodimerization activity(GO:0042803)
1.3 16.8 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.2 7.5 GO:0048156 tau protein binding(GO:0048156)
1.2 4.8 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
1.2 5.9 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
1.2 16.6 GO:0005243 gap junction channel activity(GO:0005243)
1.2 4.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.1 9.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.1 4.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
1.0 10.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
1.0 9.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.0 4.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.9 3.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 4.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.9 9.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.9 4.4 GO:0015288 porin activity(GO:0015288)
0.9 6.9 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.8 3.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.8 6.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8 5.0 GO:0019215 intermediate filament binding(GO:0019215)
0.8 7.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.7 32.2 GO:0017022 myosin binding(GO:0017022)
0.7 4.4 GO:0022829 wide pore channel activity(GO:0022829)
0.7 5.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.7 6.6 GO:0032977 membrane insertase activity(GO:0032977)
0.7 10.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.7 5.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.6 9.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 5.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 2.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.6 3.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 3.0 GO:0008494 translation activator activity(GO:0008494)
0.6 4.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 2.9 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.6 1.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 2.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.6 1.7 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.6 5.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.6 1.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 13.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 22.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 6.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.5 4.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 6.8 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.5 13.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 5.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.5 2.0 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.5 5.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.5 5.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.5 7.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.5 8.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.5 3.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 6.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.5 1.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 10.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 5.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 4.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 12.0 GO:0005272 sodium channel activity(GO:0005272)
0.4 12.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 1.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.4 20.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 10.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 2.9 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.4 7.5 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.4 12.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 2.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 6.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.4 8.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.4 1.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 7.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.4 8.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 7.3 GO:0015026 coreceptor activity(GO:0015026)
0.4 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 3.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 12.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 3.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 3.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 1.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.4 5.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 7.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.3 1.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 4.0 GO:0070840 dynein complex binding(GO:0070840)
0.3 2.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.3 3.6 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.3 1.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 14.8 GO:0019902 phosphatase binding(GO:0019902)
0.3 5.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.3 8.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 2.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 6.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 0.9 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.3 3.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 1.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 26.9 GO:0051082 unfolded protein binding(GO:0051082)
0.3 4.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 3.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 3.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 3.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 3.3 GO:0045503 dynein light chain binding(GO:0045503)
0.2 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 4.2 GO:0001671 ATPase activator activity(GO:0001671)
0.2 9.3 GO:0030145 manganese ion binding(GO:0030145)
0.2 11.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 10.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 4.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 1.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 20.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 4.0 GO:0002039 p53 binding(GO:0002039)
0.2 1.3 GO:0070697 receptor serine/threonine kinase binding(GO:0033612) transmembrane receptor protein serine/threonine kinase binding(GO:0070696) activin receptor binding(GO:0070697)
0.2 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 2.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 9.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 2.3 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 9.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 1.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 2.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 2.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 4.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 10.7 GO:0005178 integrin binding(GO:0005178)
0.2 1.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 5.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.2 4.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 0.5 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 1.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 59.4 GO:0051015 actin filament binding(GO:0051015)
0.2 3.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 9.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 6.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 54.9 GO:0015631 tubulin binding(GO:0015631)
0.2 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 21.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 9.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 3.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 20.6 GO:0008083 growth factor activity(GO:0008083)
0.1 2.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 5.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 7.6 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 3.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 5.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 42.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 47.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 2.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 2.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0005042 netrin receptor activity(GO:0005042)
0.1 17.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 84.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.7 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.7 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.0 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 5.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 2.0 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 1.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 4.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 5.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.1 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 2.5 GO:0019003 GDP binding(GO:0019003)
0.1 5.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.9 GO:0008201 heparin binding(GO:0008201)
0.1 9.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.9 GO:0031267 small GTPase binding(GO:0031267)
0.1 3.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.3 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.0 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 2.7 GO:0009881 photoreceptor activity(GO:0009881)
0.1 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 6.7 GO:0005179 hormone activity(GO:0005179)
0.0 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.5 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 5.3 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 2.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 34.0 GO:0003723 RNA binding(GO:0003723)
0.0 1.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 80.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 8.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 8.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 7.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 9.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 9.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 5.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 13.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 14.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.2 5.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 5.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 9.0 PID LKB1 PATHWAY LKB1 signaling events
0.2 7.8 PID NOTCH PATHWAY Notch signaling pathway
0.2 6.5 PID BMP PATHWAY BMP receptor signaling
0.2 27.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 4.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 1.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.7 PID ATM PATHWAY ATM pathway
0.1 2.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 9.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.7 PID P73PATHWAY p73 transcription factor network
0.1 1.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 32.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
1.0 11.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.9 15.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.8 4.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.7 17.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.7 6.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 9.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 10.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.6 6.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.5 18.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.5 6.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 8.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.5 4.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 4.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 12.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 7.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3 7.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 1.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 2.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 11.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 8.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 2.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 2.0 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 2.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 3.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 1.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 6.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 5.3 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 1.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 6.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 6.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 17.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.3 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 1.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.6 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 6.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus