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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr4a2b

Z-value: 1.00

Motif logo

Transcription factors associated with nr4a2b

Gene Symbol Gene ID Gene Info
ENSDARG00000044532 nuclear receptor subfamily 4, group A, member 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a2bdr11_v1_chr6_+_12462079_124620790.391.1e-04Click!

Activity profile of nr4a2b motif

Sorted Z-values of nr4a2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_40150612 13.97 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr7_+_31871830 13.76 ENSDART00000139899
myosin binding protein C, cardiac
chr6_-_39764995 11.40 ENSDART00000085277
phosphofructokinase, muscle b
chr11_+_11201096 11.33 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr12_-_26415499 10.85 ENSDART00000185779
synaptopodin 2-like b
chr14_-_17121676 10.42 ENSDART00000170154
ENSDART00000060479
smoothelin-like 1
chr3_+_39566999 10.34 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr6_-_39765546 9.55 ENSDART00000185767
phosphofructokinase, muscle b
chr24_+_25471196 9.05 ENSDART00000066625
small muscle protein, X-linked
chr12_-_26423439 8.62 ENSDART00000113978
synaptopodin 2-like b
chr3_+_30257582 8.37 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr10_-_17745345 7.63 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
chr2_-_48753873 7.13 ENSDART00000189556

chr6_-_21189295 6.69 ENSDART00000137136
obscurin-like 1a
chr5_-_68093169 6.60 ENSDART00000051849
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr11_+_1409622 5.79 ENSDART00000157042
protein phosphatase 1, regulatory subunit 3Db
chr20_-_10120442 5.54 ENSDART00000144970
Meis homeobox 2b
chr6_-_31348999 5.28 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr24_+_34089977 5.16 ENSDART00000157466
ankyrin repeat and SOCS box containing 10
chr13_-_41155472 5.14 ENSDART00000160588
si:dkeyp-86d6.2
chr7_+_25913225 5.10 ENSDART00000129924
high mobility group box 3a
chr5_+_1278092 5.04 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr3_+_31177972 4.97 ENSDART00000185954
C-type lectin domain containing 19A
chr3_-_22212764 4.82 ENSDART00000155490
microtubule-associated protein tau b
chr17_-_12389259 4.43 ENSDART00000185724
synaptosomal-associated protein, 25b
chr5_-_16983336 4.39 ENSDART00000038740
polypeptide N-acetylgalactosaminyltransferase 9
chr22_+_30184039 4.28 ENSDART00000049075
adducin 3 (gamma) a
chr4_-_4932619 4.26 ENSDART00000103293
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr9_+_31795343 4.02 ENSDART00000139584
integrin, beta-like 1
chr8_-_14052349 3.94 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr8_+_13106760 3.84 ENSDART00000029308
integrin, beta 4
chr3_-_28258462 3.82 ENSDART00000191573
RNA binding fox-1 homolog 1
chr12_+_14084291 3.62 ENSDART00000189734
si:ch211-217a12.1
chr12_+_46708920 3.55 ENSDART00000153089
exocyst complex component 7
chr21_+_5080789 3.52 ENSDART00000024199
ATP synthase F1 subunit alpha
chr6_-_35738836 3.51 ENSDART00000111642
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr6_-_10835849 3.51 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr13_-_21739142 3.47 ENSDART00000078460
si:dkey-191g9.5
chr3_-_46818001 3.45 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr7_+_38588866 3.43 ENSDART00000015682
NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase)
chr3_-_15154871 3.43 ENSDART00000147704
si:dkey-282h22.5
chr2_-_32457919 3.31 ENSDART00000132792
ENSDART00000041319
solute carrier family 4 (anion exchanger), member 2a
chr25_-_16969922 3.29 ENSDART00000111158
tp53-induced glycolysis and apoptosis regulator a
chr6_+_13206516 3.13 ENSDART00000036927
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr3_+_23687909 3.12 ENSDART00000046638
homeobox B8a
chr11_-_21363834 3.10 ENSDART00000080051
si:dkey-85p17.3
chr5_+_36611128 3.10 ENSDART00000097684
neuro-oncological ventral antigen 1
chr9_+_42066030 3.08 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr8_-_17997845 3.07 ENSDART00000121660
acyl-CoA thioesterase 11b
chr1_+_16127825 2.77 ENSDART00000122503
tumor suppressor candidate 3
chr9_-_21067971 2.77 ENSDART00000004333
T-box 15
chr8_+_39634114 2.75 ENSDART00000144293
musashi RNA-binding protein 1
chr10_+_41668483 2.67 ENSDART00000127073
leucine rich repeat containing 75Bb
chr14_+_30340251 2.67 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr1_-_58868306 2.64 ENSDART00000166615
dynamin 2b
chr22_-_11833317 2.58 ENSDART00000125423
ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr3_-_46817838 2.55 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr3_+_17806213 2.52 ENSDART00000055890
zinc finger protein 385C
chr7_-_19146925 2.52 ENSDART00000142924
ENSDART00000009695
kirre like nephrin family adhesion molecule 1a
chr6_-_10320676 2.50 ENSDART00000151247
sodium channel, voltage-gated, type I like, alpha b
chr18_+_30511230 2.46 ENSDART00000078888
dual specificity phosphatase 22a
chr15_+_20403903 2.43 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr2_+_34767171 2.40 ENSDART00000145451
astrotactin 1
chr4_-_16451375 2.33 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr17_+_7595356 2.21 ENSDART00000130625
si:dkeyp-110a12.4
chr17_+_30545895 2.19 ENSDART00000076739
NHS-like 1a
chr18_+_9382847 2.04 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr18_+_27926839 1.99 ENSDART00000191835
homeodomain interacting protein kinase 3b
chr18_+_31410652 1.98 ENSDART00000098504
differentially expressed in FDCP 8 homolog (mouse)
chr8_-_979735 1.97 ENSDART00000149612
zinc finger protein 366
chr19_+_32158010 1.97 ENSDART00000005255
mitochondrial ribosomal protein L53
chr6_-_29288155 1.96 ENSDART00000078630
NME/NM23 family member 7
chr7_+_44484853 1.96 ENSDART00000189079
ENSDART00000121826
brain expressed, associated with NEDD4, 1
chr11_+_2172335 1.93 ENSDART00000170593
homeobox C12b
chr6_-_50404732 1.87 ENSDART00000055510
reactive oxygen species modulator 1
chr8_-_44004135 1.82 ENSDART00000136269
RIMS binding protein 2
chr6_+_29288223 1.81 ENSDART00000112099
zgc:172121
chr12_-_29305220 1.73 ENSDART00000153458
SH2 domain containing 4Bb
chr16_+_20161805 1.73 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr12_-_47648538 1.70 ENSDART00000108477
fumarate hydratase
chr18_-_14922872 1.70 ENSDART00000091722
pannexin 2
chr14_+_30413758 1.69 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr24_+_22022109 1.67 ENSDART00000133686
rhophilin associated tail protein 1-like
chr9_+_24065855 1.66 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr7_+_38667066 1.65 ENSDART00000013394
mitochondrial carrier homolog 2
chr13_+_21768447 1.62 ENSDART00000100941
coiled-coil-helix-coiled-coil-helix domain containing 1
chr1_-_30689004 1.61 ENSDART00000018827
dachshund c
chr25_+_16214854 1.57 ENSDART00000109672
ENSDART00000190093
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr2_-_11912347 1.57 ENSDART00000023851
abhydrolase domain containing 3
chr23_+_21638258 1.54 ENSDART00000104188
immunoglobin superfamily, member 21b
chr12_+_36891483 1.52 ENSDART00000048927
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr6_+_29288006 1.49 ENSDART00000043496
zgc:172121
chr22_+_31821815 1.49 ENSDART00000159825
dedicator of cytokinesis 3
chr1_+_31638274 1.47 ENSDART00000057885
fibroblast growth factor 8 b
chr17_-_17764801 1.44 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr5_-_26330313 1.44 ENSDART00000148656
ARVCF, delta catenin family member b
chr24_+_684924 1.44 ENSDART00000186103
si:ch211-188f17.1
chr24_-_24848612 1.41 ENSDART00000190941
corticotropin releasing hormone b
chr13_-_27660955 1.38 ENSDART00000188651
ENSDART00000134494
regulating synaptic membrane exocytosis 1a
chr16_-_25233515 1.36 ENSDART00000058943
zgc:110182
chr15_+_1705167 1.34 ENSDART00000081940
otolin 1b
chr7_-_31794878 1.33 ENSDART00000099748
nucleosome assembly protein 1-like 4b
chr1_-_52167509 1.29 ENSDART00000184935

chr5_+_60928576 1.28 ENSDART00000131041
double C2-like domains, beta
chr2_-_44971551 1.26 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr1_-_46875493 1.25 ENSDART00000115081
1-acylglycerol-3-phosphate O-acyltransferase 3
chr24_-_8214253 1.17 ENSDART00000160432

chr6_-_29515709 1.16 ENSDART00000180205
peroxisomal biogenesis factor 5-like a
chr1_+_54115839 1.15 ENSDART00000180214

chr5_+_24156170 1.13 ENSDART00000136570
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr2_+_16585549 1.12 ENSDART00000134135
si:dkeyp-13a3.10
chr23_-_45504991 1.10 ENSDART00000148761
collagen type XXIV alpha 1
chr16_-_11859309 1.09 ENSDART00000145754
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr11_+_12175162 1.07 ENSDART00000125446
si:ch211-156l18.7
chr1_+_19332837 1.06 ENSDART00000078594
tyrosinase-related protein 1b
chr2_-_38282079 1.05 ENSDART00000145808
si:ch211-10e2.1
chr18_-_42333428 1.02 ENSDART00000034225
contactin 5
chr9_+_35860975 1.02 ENSDART00000134447
regulator of calcineurin 1a
chr23_-_28141419 1.01 ENSDART00000133039
tachykinin 3a
chr2_-_41562868 1.01 ENSDART00000084597
D-2-hydroxyglutarate dehydrogenase
chr4_-_2975461 1.00 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr23_+_24272421 0.98 ENSDART00000029974
chloride channel K
chr14_+_35023923 0.97 ENSDART00000172171
early B cell factor 3a
chr14_+_30413312 0.96 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr1_-_23110740 0.95 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr2_-_56649883 0.92 ENSDART00000191786
glutathione peroxidase 4b
chr5_-_13076779 0.92 ENSDART00000192826
yippee-like 1
chr8_+_8699085 0.88 ENSDART00000021209
ubiquitously-expressed, prefoldin-like chaperone
chr8_+_20825987 0.87 ENSDART00000133309
si:ch211-133l5.4
chr20_-_1151265 0.86 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr3_-_37351225 0.84 ENSDART00000174685
si:ch211-278a6.1
chr1_+_44826367 0.83 ENSDART00000146962
zgc:165520
chr14_+_36628131 0.83 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr4_-_57416684 0.81 ENSDART00000169434
si:dkey-122c11.7
chr10_+_11265387 0.77 ENSDART00000038888
hydroxysteroid dehydrogenase like 2
chr1_+_20593653 0.72 ENSDART00000132440
si:ch211-142c4.1
chr3_-_54500354 0.71 ENSDART00000124215
thyroid hormone receptor interactor 10a
chr24_-_6628359 0.70 ENSDART00000169731
Rho GTPase activating protein 21a
chr5_-_67721368 0.70 ENSDART00000134386
Rho GTPase activating protein 31
chr10_-_29892486 0.69 ENSDART00000099983
brain-specific homeobox
chr18_-_4957022 0.68 ENSDART00000101686
zinc finger, B-box domain containing
chr5_-_10007897 0.68 ENSDART00000109052
Danio rerio uncharacterized LOC799523 (LOC799523), mRNA.
chr7_+_42206847 0.66 ENSDART00000149250
phosphorylase kinase, beta
chr6_+_40775800 0.62 ENSDART00000085090
si:ch211-157b11.8
chr15_+_33691455 0.57 ENSDART00000170329
histone deacetylase 12
chr10_+_36354863 0.52 ENSDART00000159675
odorant receptor, family C, subfamily 104, member 1
chr23_+_36063599 0.52 ENSDART00000103147
homeobox C12a
chr23_+_27068225 0.51 ENSDART00000054238
major intrinsic protein of lens fiber a
chr19_+_19652439 0.51 ENSDART00000165934
3-hydroxyisobutyrate dehydrogenase a
chr7_+_20524064 0.50 ENSDART00000052917
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr7_-_24005268 0.50 ENSDART00000173608
si:dkey-183c6.9
chr21_+_37411547 0.50 ENSDART00000076320
mitochondrial ribosomal protein S17
chr16_-_16619854 0.48 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cytochrome P450, family 21, subfamily A, polypeptide 2
chr14_+_33882973 0.47 ENSDART00000019396
chloride intracellular channel 2
chr10_-_20524592 0.45 ENSDART00000185048
DDHD domain containing 2
chr7_-_24046999 0.44 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr12_+_30368145 0.44 ENSDART00000153454
si:ch211-225b10.4
chr19_+_14059349 0.41 ENSDART00000166230
trophoblast glycoprotein a
chr10_+_7563755 0.40 ENSDART00000165877
purine-rich element binding protein G
chr7_-_31794476 0.37 ENSDART00000142385
nucleosome assembly protein 1-like 4b
chr5_+_59494079 0.31 ENSDART00000148727
GTF2I repeat domain containing 1
chr24_-_1021318 0.29 ENSDART00000181403
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr8_+_53120278 0.29 ENSDART00000125232
nuclear receptor subfamily 2, group C, member 2
chr1_-_21287724 0.29 ENSDART00000193900
neuropeptide Y receptor Y1
chr17_+_30546579 0.29 ENSDART00000154385
NHS-like 1a
chr9_-_3653259 0.23 ENSDART00000140425
ENSDART00000025332
glutamate decarboxylase 1a
chr18_-_2433011 0.23 ENSDART00000181922
ENSDART00000193276

chr8_-_23578660 0.21 ENSDART00000039080
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr8_-_42238543 0.20 ENSDART00000062697
GDNF family receptor alpha 2a
chr4_-_8060962 0.15 ENSDART00000146622
WNK lysine deficient protein kinase 1b
chr5_+_29652198 0.15 ENSDART00000184083
TSC complex subunit 1a
chr7_+_22702225 0.13 ENSDART00000173672
si:dkey-165a24.9
chr10_-_20524387 0.13 ENSDART00000159060
DDHD domain containing 2
chr21_+_4320769 0.13 ENSDART00000168553
si:dkey-84o3.4
chr24_-_6024466 0.10 ENSDART00000040865
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_-_40102836 0.09 ENSDART00000147317
ciliary neurotrophic factor
chr1_-_53988017 0.09 ENSDART00000003097
si:ch211-133l11.10
chr19_-_703898 0.06 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr6_+_3282809 0.02 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
lysine (K)-specific demethylase 4A, genome duplicate a
chr5_+_61738276 0.01 ENSDART00000186256
RAS like family 10 member B
chr20_-_45722895 0.00 ENSDART00000153273
glycerophosphocholine phosphodiesterase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 13.8 GO:0003210 cardiac atrium formation(GO:0003210)
1.9 20.9 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.4 5.8 GO:0051193 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
1.3 6.6 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
1.1 5.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.9 10.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.7 5.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.6 17.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.5 1.4 GO:0035902 response to immobilization stress(GO:0035902)
0.4 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.4 2.4 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 2.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.4 7.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 1.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.4 1.9 GO:2000379 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.4 3.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 2.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.3 4.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.6 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.3 7.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 5.8 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.3 1.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 7.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 1.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 2.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 3.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 0.9 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.2 1.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 1.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 1.7 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 2.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 7.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 0.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 6.7 GO:0010842 retina layer formation(GO:0010842)
0.1 0.7 GO:0021982 pineal gland development(GO:0021982)
0.1 4.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 3.8 GO:0021854 hypothalamus development(GO:0021854)
0.1 3.1 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 1.3 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.5 GO:0006833 water transport(GO:0006833)
0.1 10.9 GO:0006936 muscle contraction(GO:0006936)
0.1 0.8 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 2.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 3.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 3.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 5.0 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 1.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 2.4 GO:1990266 neutrophil migration(GO:1990266)
0.0 2.5 GO:0021782 glial cell development(GO:0021782)
0.0 2.8 GO:0001708 cell fate specification(GO:0001708)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 6.0 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 1.7 GO:0048565 digestive tract development(GO:0048565)
0.0 3.8 GO:0006887 exocytosis(GO:0006887)
0.0 0.7 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 20.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.8 9.1 GO:0043034 costamere(GO:0043034)
0.7 4.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.6 11.3 GO:0031430 M band(GO:0031430)
0.6 14.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.5 3.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.4 2.4 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 7.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 5.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 19.5 GO:0030018 Z disc(GO:0030018)
0.2 3.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 10.4 GO:0031941 filamentous actin(GO:0031941)
0.2 2.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 7.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 7.9 GO:0008305 integrin complex(GO:0008305)
0.1 3.5 GO:0000145 exocyst(GO:0000145)
0.1 2.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.7 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.7 GO:0005921 gap junction(GO:0005921)
0.1 10.4 GO:0014069 postsynaptic density(GO:0014069)
0.1 2.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 3.6 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 2.0 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 5.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.4 GO:0031514 motile cilium(GO:0031514)
0.0 2.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.5 GO:0030425 dendrite(GO:0030425)
0.0 4.8 GO:0005874 microtubule(GO:0005874)
0.0 2.5 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 20.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.3 6.6 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
1.3 10.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.3 13.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.9 3.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.8 3.3 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.5 1.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 1.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.5 10.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 3.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.4 5.8 GO:2001069 glycogen binding(GO:2001069)
0.3 3.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 5.1 GO:0008301 DNA binding, bending(GO:0008301)
0.3 1.6 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 0.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 3.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 7.9 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 4.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.7 GO:0022829 wide pore channel activity(GO:0022829)
0.1 2.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 3.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 1.0 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 5.3 GO:0030276 clathrin binding(GO:0030276)
0.0 15.2 GO:0008017 microtubule binding(GO:0008017)
0.0 30.3 GO:0003779 actin binding(GO:0003779)
0.0 2.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 4.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 1.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 3.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 4.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 6.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 2.6 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 2.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.0 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 11.9 GO:0005102 receptor binding(GO:0005102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 10.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 5.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production