PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
nfkb1 Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000105261	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
rela Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000098696	v-rel avian reticuloendotheliosis viral oncogene homolog A

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nfkb1	dr11_v1_chr14_-_49859747_49859823	0.49	6.0e-07	Click!
rela	dr11_v1_chr7_-_804515_804515	0.30	3.0e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_18716 Show fit	21.53	ENSDART00000172454 ENSDART00000161190	nfkbiz Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr24_+_26006730 Show fit	21.12	ENSDART00000140384 ENSDART00000139184	ccl20b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 20b
chr20_+_16881883 Show fit	19.49	ENSDART00000130107	nfkbiaa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr20_-_51307815 Show fit	19.06	ENSDART00000098833	nfkbie Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr2_+_42191592 Show fit	17.31	ENSDART00000144716	cavin4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caveolae associated protein 4a
chr7_+_12950507 Show fit	16.77	ENSDART00000067629 ENSDART00000158004	saa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serum amyloid A
chr8_+_24281512 Show fit	16.09	ENSDART00000062845	mmp9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix metallopeptidase 9
chr1_-_37377509 Show fit	16.01	ENSDART00000113542	tnip2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNFAIP3 interacting protein 2
chr1_-_52437056 Show fit	13.78	ENSDART00000138337	si:ch211-217k17.12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-217k17.12
chr7_-_34262080 Show fit	13.65	ENSDART00000183246	si:ch211-98n17.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-98n17.5
chr5_+_22579975 Show fit	13.44	ENSDART00000080877	tnfsf10l4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor (ligand) superfamily, member 10 like 4
chr1_-_52431220 Show fit	13.29	ENSDART00000111256	zgc:194101 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194101
chr12_+_20641471 Show fit	13.10	ENSDART00000133654	calcoco2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium binding and coiled-coil domain 2
chr18_-_5527050 Show fit	13.03	ENSDART00000145400 ENSDART00000132498 ENSDART00000146209	zgc:153317 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:153317
chr8_-_18667693 Show fit	12.84	ENSDART00000100516	stap2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	signal transducing adaptor family member 2b
chr13_-_25819825 Show fit	12.31	ENSDART00000077612	rel Links NCBI UniProt ZFIN ENSEMBL Google Show fit	v-rel avian reticuloendotheliosis viral oncogene homolog
chr23_+_31815423 Show fit	12.27	ENSDART00000075730 ENSDART00000075726	myb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	v-myb avian myeloblastosis viral oncogene homolog
chr3_-_21242460 Show fit	12.21	ENSDART00000007293	tcap Links NCBI UniProt ZFIN ENSEMBL Google Show fit	titin-cap (telethonin)
chr15_+_32727848 Show fit	12.14	ENSDART00000161361	postnb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	periostin, osteoblast specific factor b
chr12_+_22576404 Show fit	12.00	ENSDART00000172053	capgb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	capping protein (actin filament), gelsolin-like b
chr24_-_33703504 Show fit	11.40	ENSDART00000079292	cavin4b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caveolae associated protein 4b
chr12_+_20641102 Show fit	11.23	ENSDART00000152964	calcoco2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium binding and coiled-coil domain 2
chr4_-_12795436 Show fit	11.17	ENSDART00000131026 ENSDART00000075127	b2m Links NCBI UniProt ZFIN ENSEMBL Google Show fit	beta-2-microglobulin
chr17_+_12942634 Show fit	10.33	ENSDART00000016597	nfkbiab Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr21_+_19547806 Show fit	10.26	ENSDART00000159707 ENSDART00000184869 ENSDART00000181321 ENSDART00000058487 ENSDART00000058485	rai14 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoic acid induced 14
chr9_-_51563575 Show fit	9.95	ENSDART00000167034 ENSDART00000148918	tank Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TRAF family member-associated NFKB activator
chr8_-_12432604 Show fit	9.73	ENSDART00000133350 ENSDART00000140699 ENSDART00000101174	traf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNF receptor-associated factor 1
chr23_+_19701587 Show fit	9.72	ENSDART00000104425	dnase1l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	deoxyribonuclease I-like 1
chr16_+_23403602 Show fit	9.52	ENSDART00000159848	s100w Links NCBI UniProt ZFIN ENSEMBL Google Show fit	S100 calcium binding protein W
chr16_-_29714540 Show fit	9.36	ENSDART00000067854	tnfaip8l2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor, alpha-induced protein 8-like 2b
chr14_+_3038473 Show fit	9.33	ENSDART00000026021 ENSDART00000150000	cd74a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CD74 molecule, major histocompatibility complex, class II invariant chain a
chr19_+_7124337 Show fit	9.33	ENSDART00000031380	tap2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transporter associated with antigen processing, subunit type a
chr1_-_49225890 Show fit	9.33	ENSDART00000111598	cxcl18b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-X-C motif) ligand 18b
chr6_+_54576520 Show fit	9.28	ENSDART00000093199 ENSDART00000127519 ENSDART00000157142	tead3b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TEA domain family member 3 b
chr14_-_4121052 Show fit	9.22	ENSDART00000167074	irf2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 2
chr6_+_3334710 Show fit	9.15	ENSDART00000132848	st3gal3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr19_-_7144548 Show fit	9.09	ENSDART00000147177 ENSDART00000134850	psmb8a Links NCBI UniProt ZFIN ENSEMBL Google Show fit psmb13a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit beta 8A proteasome subunit beta 13a
chr24_+_22731228 Show fit	8.78	ENSDART00000146733	si:dkey-225k4.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-225k4.1
chr6_-_436658 Show fit	8.75	ENSDART00000191515	grap2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	GRB2-related adaptor protein 2b
chr14_-_4120636 Show fit	8.68	ENSDART00000059230	irf2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 2
chr9_+_41156287 Show fit	8.68	ENSDART00000189195 ENSDART00000186270	stat4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	signal transducer and activator of transcription 4
chr23_-_32162810 Show fit	8.59	ENSDART00000155905	nr4a1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear receptor subfamily 4, group A, member 1
chr5_-_42878178 Show fit	8.54	ENSDART00000162981	CXCL11 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	C-X-C motif chemokine ligand 11
chr9_-_98982 Show fit	8.32	ENSDART00000147882	lims2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	LIM and senescent cell antigen-like domains 2
chr24_+_25919809 Show fit	8.07	ENSDART00000006615	map3k15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	mitogen-activated protein kinase kinase kinase 15
chr14_-_1646360 Show fit	8.01	ENSDART00000186528	LO018106.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr2_+_45191049 Show fit	7.95	ENSDART00000165392	ccl20a.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 20a, duplicate 3
chr20_+_23501535 Show fit	7.94	ENSDART00000177922 ENSDART00000058532	palld Links NCBI UniProt ZFIN ENSEMBL Google Show fit	palladin, cytoskeletal associated protein
chr21_-_22693730 Show fit	7.93	ENSDART00000158342	gig2d Links NCBI UniProt ZFIN ENSEMBL Google Show fit	grass carp reovirus (GCRV)-induced gene 2d
chr6_+_2030703 Show fit	7.82	ENSDART00000109679 ENSDART00000187502 ENSDART00000191165 ENSDART00000187544	quo Links NCBI UniProt ZFIN ENSEMBL Google Show fit	quattro
chr18_-_11729 Show fit	7.77	ENSDART00000159781	WHAMM Links NCBI UniProt ZFIN ENSEMBL Google Show fit	WAS protein homolog associated with actin, golgi membranes and microtubules
chr9_+_41156818 Show fit	7.63	ENSDART00000105764 ENSDART00000147052	stat4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	signal transducer and activator of transcription 4
chr22_-_651719 Show fit	7.39	ENSDART00000148692	apobec2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr12_-_30760971 Show fit	7.31	ENSDART00000066257	entpd1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ectonucleoside triphosphate diphosphohydrolase 1
chr21_+_30937690 Show fit	7.13	ENSDART00000022562	rhogb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ras homolog family member Gb
chr21_-_435466 Show fit	6.87	ENSDART00000110297	klf4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Kruppel-like factor 4
chr5_+_13373593 Show fit	6.80	ENSDART00000051668 ENSDART00000183883	ccl19a.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr11_+_8129536 Show fit	6.66	ENSDART00000158112 ENSDART00000011183	prkacba Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein kinase, cAMP-dependent, catalytic, beta a
chr23_-_12423778 Show fit	6.56	ENSDART00000124091	wfdc2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	WAP four-disulfide core domain 2
chr23_-_38054 Show fit	6.50	ENSDART00000170393	CABZ01074076.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr23_+_42819221 Show fit	6.36	ENSDART00000180495	myl9a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin, light chain 9a, regulatory
chr13_+_32148338 Show fit	6.33	ENSDART00000188591	osr1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	odd-skipped related transciption factor 1
chr2_-_51772438 Show fit	6.27	ENSDART00000170241	BX908782.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Danio rerio three-finger protein 5 (LOC100003647), mRNA.
chr8_-_13029297 Show fit	6.24	ENSDART00000144305	dennd2da Links NCBI UniProt ZFIN ENSEMBL Google Show fit	DENN/MADD domain containing 2Da
chr24_+_80653 Show fit	6.17	ENSDART00000158473 ENSDART00000129135	reck Links NCBI UniProt ZFIN ENSEMBL Google Show fit	reversion-inducing-cysteine-rich protein with kazal motifs
chr6_+_3334392 Show fit	6.17	ENSDART00000133707 ENSDART00000130879	st3gal3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr1_-_52447364 Show fit	6.03	ENSDART00000140740	si:ch211-217k17.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-217k17.10
chr8_+_25302172 Show fit	5.99	ENSDART00000046182 ENSDART00000145316	gstm.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glutathione S-transferase mu tandem duplicate 3
chr19_+_19767567 Show fit	5.89	ENSDART00000169074	hoxa3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	homeobox A3a
chr19_+_7043634 Show fit	5.88	ENSDART00000133954	mhc1uka Links NCBI UniProt ZFIN ENSEMBL Google Show fit	major histocompatibility complex class I UKA
chr16_-_25739331 Show fit	5.84	ENSDART00000189455	bcl3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	B cell CLL/lymphoma 3
chr5_+_24086227 Show fit	5.83	ENSDART00000051549 ENSDART00000177458 ENSDART00000135934	tp53 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor protein p53
chr4_-_149334 Show fit	5.82	ENSDART00000163280	tbk1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TANK-binding kinase 1
chr1_-_52443379 Show fit	5.78	ENSDART00000144676	si:ch211-217k17.11 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-217k17.11
chr7_+_29293452 Show fit	5.76	ENSDART00000127358	si:ch211-112g6.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-112g6.4
chr13_+_22717366 Show fit	5.75	ENSDART00000134122	nfkb2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr6_-_442163 Show fit	5.70	ENSDART00000163564 ENSDART00000189134 ENSDART00000169789	grap2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	GRB2-related adaptor protein 2b
chr16_+_38394371 Show fit	5.55	ENSDART00000137954	cd83 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CD83 molecule
chr16_-_35975254 Show fit	5.55	ENSDART00000167537	eva1ba Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eva-1 homolog Ba (C. elegans)
chr5_+_9246018 Show fit	5.44	ENSDART00000081769 ENSDART00000183189	susd1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sushi domain containing 1
chr23_+_10347851 Show fit	5.25	ENSDART00000127667	krt18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 18
chr11_+_6456146 Show fit	5.23	ENSDART00000036939	gadd45ba Links NCBI UniProt ZFIN ENSEMBL Google Show fit	growth arrest and DNA-damage-inducible, beta a
chr25_-_13188214 Show fit	5.17	ENSDART00000187298	si:ch211-147m6.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-147m6.1
chr3_-_32170850 Show fit	5.11	ENSDART00000055307 ENSDART00000157366	tnnt1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin T type 1 (skeletal, slow)
chr4_+_70151160 Show fit	5.04	ENSDART00000111816	si:dkey-3h2.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-3h2.4
chr17_-_29249258 Show fit	5.04	ENSDART00000031458	traf3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNF receptor-associated factor 3
chr17_+_51746830 Show fit	4.96	ENSDART00000184230	odc1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ornithine decarboxylase 1
chr7_-_22632518 Show fit	4.94	ENSDART00000161046	si:dkey-112a7.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-112a7.4
chr5_+_13385837 Show fit	4.93	ENSDART00000191190	ccl19a.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr9_-_6380653 Show fit	4.92	ENSDART00000078523	ecrg4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	esophageal cancer related gene 4a
chr7_-_22632690 Show fit	4.87	ENSDART00000165245	si:dkey-112a7.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-112a7.4
chr14_+_36885524 Show fit	4.85	ENSDART00000032547	lect2l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	leukocyte cell-derived chemotaxin 2 like
chr2_-_2642476 Show fit	4.80	ENSDART00000124032	serbp1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SERPINE1 mRNA binding protein 1b
chr9_-_23894392 Show fit	4.77	ENSDART00000133417	asb18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ankyrin repeat and SOCS box containing 18
chr14_+_36889893 Show fit	4.77	ENSDART00000124159	si:ch211-132p1.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-132p1.3
chr13_-_51846224 Show fit	4.74	ENSDART00000184663	LT631684.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr13_+_30692669 Show fit	4.74	ENSDART00000187818	CR762483.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr6_+_18298444 Show fit	4.67	ENSDART00000166018	card14 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase recruitment domain family, member 14
chr25_-_6557854 Show fit	4.64	ENSDART00000181740	cspg4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chondroitin sulfate proteoglycan 4
chr13_+_22717939 Show fit	4.61	ENSDART00000188288	nfkb2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr17_-_7733037 Show fit	4.59	ENSDART00000064657	stx11a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	syntaxin 11a
chr7_+_57677120 Show fit	4.55	ENSDART00000110623	arsj Links NCBI UniProt ZFIN ENSEMBL Google Show fit	arylsulfatase family, member J
chr11_-_25853212 Show fit	4.43	ENSDART00000145655	tmem51b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 51b
chr1_+_27690 Show fit	4.38	ENSDART00000162928	eed Links NCBI UniProt ZFIN ENSEMBL Google Show fit	embryonic ectoderm development
chr1_+_33328857 Show fit	4.27	ENSDART00000137151	mxra5a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix-remodelling associated 5a
chr3_+_57820913 Show fit	4.26	ENSDART00000168101	CU571328.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr9_-_32604414 Show fit	4.19	ENSDART00000088876 ENSDART00000166502	satb2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SATB homeobox 2
chr1_-_59232267 Show fit	4.18	ENSDART00000169658 ENSDART00000163257	akap8l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	A kinase (PRKA) anchor protein 8-like
chr13_-_39947335 Show fit	4.18	ENSDART00000056996	sfrp5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	secreted frizzled-related protein 5
chr19_+_46113828 Show fit	4.16	ENSDART00000159331 ENSDART00000161826	rbm24a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	RNA binding motif protein 24a
chr14_-_49859747 Show fit	4.16	ENSDART00000169456 ENSDART00000164967	nfkb1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr15_-_4152582 Show fit	4.16	ENSDART00000171942	si:dkey-83h2.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-83h2.5
chr2_+_36004381 Show fit	4.12	ENSDART00000098706	lamc2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	laminin, gamma 2
chr15_+_27364394 Show fit	4.09	ENSDART00000122101	tbx2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	T-box 2b
chr2_+_21356242 Show fit	4.03	ENSDART00000145670 ENSDART00000146600	ctdsplb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr22_+_16497670 Show fit	4.02	ENSDART00000014330	ier5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	immediate early response 5
chr12_+_10631266 Show fit	4.01	ENSDART00000161455	csf3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	colony stimulating factor 3 (granulocyte) a
chr7_+_19835569 Show fit	3.98	ENSDART00000149812	ovol1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ovo-like zinc finger 1a
chr7_-_59123066 Show fit	3.92	ENSDART00000175438	dennd4c Links NCBI UniProt ZFIN ENSEMBL Google Show fit	DENN/MADD domain containing 4C
chr7_-_20241346 Show fit	3.92	ENSDART00000173619 ENSDART00000127699	si:ch73-335l21.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-335l21.4
chr23_-_33738570 Show fit	3.90	ENSDART00000131680	si:ch211-210c8.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-210c8.7
chr14_-_30967284 Show fit	3.83	ENSDART00000149435	il2rgb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 2 receptor, gamma b
chr6_-_54815886 Show fit	3.78	ENSDART00000180793 ENSDART00000007498	tnni1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I type 1b (skeletal, slow)
chr6_-_52675630 Show fit	3.78	ENSDART00000083830	sdc4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	syndecan 4
chr11_+_14333441 Show fit	3.78	ENSDART00000171969	ptbp1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	polypyrimidine tract binding protein 1b
chr22_+_661711 Show fit	3.65	ENSDART00000113795	elf3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr14_+_30773764 Show fit	3.63	ENSDART00000186961	atl3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	atlastin 3
chr12_+_48634927 Show fit	3.62	ENSDART00000168441	zgc:165653 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:165653
chr19_-_10432134 Show fit	3.58	ENSDART00000081440	il11b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 11b
chr8_+_22355909 Show fit	3.54	ENSDART00000146457 ENSDART00000142883	zgc:153631 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:153631
chr6_+_49771626 Show fit	3.53	ENSDART00000134207	ctsz Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin Z
chr14_+_49376011 Show fit	3.47	ENSDART00000020961	tnip1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNFAIP3 interacting protein 1
chr7_-_8309505 Show fit	3.44	ENSDART00000182530	f13a1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	coagulation factor XIII, A1 polypeptide b
chr6_+_19933763 Show fit	3.40	ENSDART00000166192	pik3r5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoinositide-3-kinase, regulatory subunit 5
chr22_-_31517300 Show fit	3.38	ENSDART00000164799	slc6a6b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 6 (neurotransmitter transporter), member 6b
chr19_+_43119698 Show fit	3.36	ENSDART00000167847 ENSDART00000186962 ENSDART00000187305	eef1a1l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation elongation factor 1 alpha 1, like 1
chr8_-_20230559 Show fit	3.33	ENSDART00000193677	mllt1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	MLLT1, super elongation complex subunit a
chr3_+_22273123 Show fit	3.32	ENSDART00000044157	scn4ab Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sodium channel, voltage-gated, type IV, alpha, b
chr12_+_46740584 Show fit	3.28	ENSDART00000171563	plaub Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plasminogen activator, urokinase b
chr14_-_6987649 Show fit	3.25	ENSDART00000060990	eif4ebp3l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 4E binding protein 3, like
chr2_-_45191319 Show fit	3.23	ENSDART00000192272	CR407590.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr23_-_437467 Show fit	3.14	ENSDART00000192106	tspan2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 2b
chr2_-_53592532 Show fit	3.12	ENSDART00000184066	ccl25a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 25a
chr1_+_33322555 Show fit	3.12	ENSDART00000113486	mxra5a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix-remodelling associated 5a
chr25_+_8955530 Show fit	3.12	ENSDART00000156444	si:ch211-256a21.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-256a21.4
chr7_-_73843720 Show fit	3.11	ENSDART00000111622	caap1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase activity and apoptosis inhibitor 1
chr17_+_8175998 Show fit	3.09	ENSDART00000131200	myct1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myc target 1b
chr16_+_35535375 Show fit	3.05	ENSDART00000171675	cited4b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr6_+_49771372 Show fit	3.04	ENSDART00000063251	ctsz Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin Z
chr10_+_8875195 Show fit	3.04	ENSDART00000141045	itga2.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr22_+_8536838 Show fit	3.02	ENSDART00000132998	si:ch73-27e22.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-27e22.7
chr17_-_2685026 Show fit	2.95	ENSDART00000191014 ENSDART00000179309	ptpn21 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine phosphatase, non-receptor type 21
chr21_+_15866522 Show fit	2.95	ENSDART00000110728	gcnt4b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glucosaminyl (N-acetyl) transferase 4, core 2, b
chr4_-_12914163 Show fit	2.94	ENSDART00000140002 ENSDART00000145917 ENSDART00000141355 ENSDART00000067135	msrb3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	methionine sulfoxide reductase B3
chr3_+_59899452 Show fit	2.92	ENSDART00000064311	arhgdia Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GDP dissociation inhibitor (GDI) alpha
chr7_-_20338048 Show fit	2.87	ENSDART00000125594	zgc:194312 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194312
chr12_+_27462225 Show fit	2.85	ENSDART00000105661	meox1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	mesenchyme homeobox 1
chr7_-_22632938 Show fit	2.84	ENSDART00000159867 ENSDART00000165706	si:dkey-112a7.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-112a7.4
chr18_-_18543358 Show fit	2.83	ENSDART00000126460	il34 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 34
chr7_-_51461649 Show fit	2.82	ENSDART00000193947 ENSDART00000174328	arhgap36 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 36
chr14_+_16765992 Show fit	2.77	ENSDART00000140061	sqstm1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sequestosome 1
chr16_+_34111919 Show fit	2.76	ENSDART00000134037 ENSDART00000006061 ENSDART00000140552	tcea3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription elongation factor A (SII), 3
chr22_-_10354381 Show fit	2.75	ENSDART00000092050	stab1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	stabilin 1
chr10_+_20608676 Show fit	2.70	ENSDART00000140141	si:dkey-81j8.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-81j8.6
chr7_-_804515 Show fit	2.68	ENSDART00000159359	rela Links NCBI UniProt ZFIN ENSEMBL Google Show fit	v-rel avian reticuloendotheliosis viral oncogene homolog A
chr5_-_44496553 Show fit	2.67	ENSDART00000178081	gas1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	growth arrest-specific 1a
chr16_-_27749172 Show fit	2.64	ENSDART00000145198	steap4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	STEAP family member 4
chr5_+_9246458 Show fit	2.62	ENSDART00000081772	susd1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	sushi domain containing 1
chr21_+_45626136 Show fit	2.60	ENSDART00000158742	irf1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 1b
chr8_+_25629722 Show fit	2.59	ENSDART00000026807	wasa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr7_-_28696556 Show fit	2.57	ENSDART00000148822	adgrg1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	adhesion G protein-coupled receptor G1
chr12_-_3903886 Show fit	2.56	ENSDART00000184214 ENSDART00000041082	gdpd3b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	glycerophosphodiester phosphodiesterase domain containing 3b
chr4_-_75681004 Show fit	2.53	ENSDART00000186296	si:dkey-71l4.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-71l4.5
chr7_-_22941472 Show fit	2.53	ENSDART00000190334	tnfsf10l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNF superfamily member 10, like
chr10_+_31646020 Show fit	2.53	ENSDART00000115251	esama Links NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelial cell adhesion molecule a
chr4_+_76789395 Show fit	2.51	ENSDART00000147574	si:ch73-56d11.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-56d11.3
chr25_+_16646113 Show fit	2.50	ENSDART00000110426	cecr2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cat eye syndrome chromosome region, candidate 2
chr12_+_46745239 Show fit	2.50	ENSDART00000057179	plaub Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plasminogen activator, urokinase b
chr4_-_22311610 Show fit	2.48	ENSDART00000137814	hcls1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	hematopoietic cell-specific Lyn substrate 1
chr12_-_11349899 Show fit	2.45	ENSDART00000079645	zgc:174164 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:174164
chr19_+_20713424 Show fit	2.45	ENSDART00000129730	rab5aa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB5A, member RAS oncogene family, a
chr22_+_19425657 Show fit	2.45	ENSDART00000187531 ENSDART00000078804	si:dkey-78l4.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-78l4.5
chr5_-_44496805 Show fit	2.44	ENSDART00000110076	gas1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	growth arrest-specific 1a
chr4_+_68562464 Show fit	2.43	ENSDART00000192954	BX548011.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr7_+_34786591 Show fit	2.42	ENSDART00000173700	si:dkey-148a17.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-148a17.5
chr7_+_25053331 Show fit	2.42	ENSDART00000173998	si:dkey-23i12.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-23i12.7
chr20_-_39367895 Show fit	2.41	ENSDART00000136476 ENSDART00000021788 ENSDART00000180784	pbk Links NCBI UniProt ZFIN ENSEMBL Google Show fit	PDZ binding kinase
chr20_+_218886 Show fit	2.41	ENSDART00000002661	lama4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	laminin, alpha 4
chr15_+_17251191 Show fit	2.40	ENSDART00000156587	si:ch73-223p23.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-223p23.2
chr5_+_51909740 Show fit	2.37	ENSDART00000162541	thbs4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	thrombospondin 4a
chr1_+_17892944 Show fit	2.37	ENSDART00000013021	tlr3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	toll-like receptor 3
chr2_-_879800 Show fit	2.34	ENSDART00000019733	irf4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 4a
chr11_+_35050253 Show fit	2.32	ENSDART00000124800	fam212aa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 212, member Aa
chr14_-_40850481 Show fit	2.32	ENSDART00000173236	elf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like ETS transcription factor 1
chr4_+_77681389 Show fit	2.29	ENSDART00000099727	gbp4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	guanylate binding protein 4
chr5_+_37785152 Show fit	2.27	ENSDART00000053511 ENSDART00000189812	myo1ca Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin Ic, paralog a
chr2_-_57227542 Show fit	2.26	ENSDART00000182675 ENSDART00000159480	btbd2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	BTB (POZ) domain containing 2b
chr5_-_64168415 Show fit	2.20	ENSDART00000048395	cmlc1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cardiac myosin light chain-1
chr24_+_41273252 Show fit	2.19	ENSDART00000105526	nub1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	negative regulator of ubiquitin-like proteins 1
chr23_-_29003864 Show fit	2.19	ENSDART00000148257	casz1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	castor zinc finger 1

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.5	19.5	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
6.1	18.4	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
5.4	16.1	GO:0002631	granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
5.0	14.9	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468)
3.3	20.0	GO:0051883	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
3.1	12.2	GO:0035994	response to muscle stretch(GO:0035994)
2.5	7.4	GO:0043388	positive regulation of DNA binding(GO:0043388)
2.1	6.3	GO:0048389	intermediate mesoderm development(GO:0048389)
2.1	6.2	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
2.0	12.3	GO:0030852	regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
1.9	5.8	GO:0032197	regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
1.6	4.9	GO:0070314	G1 to G0 transition(GO:0070314)
1.6	11.4	GO:0033292	T-tubule organization(GO:0033292)
1.4	2.8	GO:0045649	regulation of macrophage differentiation(GO:0045649)
1.4	4.2	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.4	4.2	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle cell differentiation(GO:2001014)
1.4	4.1	GO:0072025	distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
1.2	7.3	GO:0071405	response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
1.0	8.3	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.0	3.1	GO:0072679	thymocyte migration(GO:0072679)
1.0	40.8	GO:0048247	lymphocyte chemotaxis(GO:0048247)
1.0	8.6	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.9	3.8	GO:0036445	neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.9	2.8	GO:0035973	aggrephagy(GO:0035973)
0.9	14.5	GO:0016203	muscle attachment(GO:0016203)
0.8	5.9	GO:0060017	parathyroid gland development(GO:0060017)
0.8	2.5	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.8	3.2	GO:0014743	regulation of muscle hypertrophy(GO:0014743)
0.8	11.2	GO:0034122	regulation of toll-like receptor signaling pathway(GO:0034121) negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.8	14.6	GO:0046686	response to cadmium ion(GO:0046686)
0.7	2.9	GO:0030091	protein repair(GO:0030091)
0.7	2.9	GO:0048939	anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.7	5.1	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7	15.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.7	2.8	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.7	10.6	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.7	2.6	GO:0015677	copper ion import(GO:0015677)
0.6	13.9	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
0.6	2.3	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320)
0.6	5.8	GO:0031639	plasminogen activation(GO:0031639)
0.6	9.7	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.6	4.0	GO:0070285	pigment cell development(GO:0070285)
0.6	5.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.5	2.2	GO:2000058	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.5	1.6	GO:0035971	peptidyl-histidine dephosphorylation(GO:0035971)
0.5	8.1	GO:0000186	activation of MAPKK activity(GO:0000186)
0.5	1.6	GO:0007567	parturition(GO:0007567) maternal process involved in parturition(GO:0060137)
0.5	2.6	GO:0070445	regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5	1.5	GO:0003091	renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.5	1.9	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4	1.3	GO:0060879	peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.4	4.2	GO:0061588	calcium activated phospholipid scrambling(GO:0061588)
0.4	2.9	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.4	2.0	GO:0033499	galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.4	1.6	GO:0090161	Golgi ribbon formation(GO:0090161)
0.4	1.6	GO:1903292	protein localization to Golgi membrane(GO:1903292)
0.4	12.0	GO:0051014	actin filament severing(GO:0051014)
0.4	2.2	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.3	10.7	GO:0055092	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.3	1.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3	14.7	GO:0007259	JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.3	9.3	GO:0035329	hippo signaling(GO:0035329)
0.3	3.5	GO:2000406	positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.3	2.8	GO:0061056	sclerotome development(GO:0061056)
0.3	9.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3	1.7	GO:0097241	hematopoietic stem cell migration to bone marrow(GO:0097241)
0.3	7.7	GO:0072089	stem cell proliferation(GO:0072089)
0.3	3.9	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.3	2.5	GO:0070527	platelet aggregation(GO:0070527)
0.2	5.1	GO:0010737	protein kinase A signaling(GO:0010737)
0.2	1.9	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2	2.6	GO:0050688	regulation of defense response to virus(GO:0050688)
0.2	3.4	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.2	1.1	GO:0010447	response to acidic pH(GO:0010447)
0.2	0.9	GO:0070255	regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.2	6.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.2	3.1	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.2	3.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.2	0.8	GO:0072003	kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.2	18.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.2	2.6	GO:0051127	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	6.0	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2	0.6	GO:0060544	regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.2	13.1	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.2	1.7	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	10.7	GO:0006469	negative regulation of protein kinase activity(GO:0006469)
0.1	6.0	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	2.9	GO:0060324	face development(GO:0060324)
0.1	5.1	GO:0007050	cell cycle arrest(GO:0007050)
0.1	1.1	GO:0003303	BMP signaling pathway involved in determination of left/right symmetry(GO:0003154) BMP signaling pathway involved in heart jogging(GO:0003303) locus ceruleus development(GO:0021703)
0.1	2.6	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	7.4	GO:0048332	mesoderm morphogenesis(GO:0048332)
0.1	1.9	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	1.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.5	GO:0090134	mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1	0.5	GO:0007412	axon target recognition(GO:0007412)
0.1	3.8	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	0.8	GO:0042214	carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1	4.1	GO:0043113	receptor clustering(GO:0043113)
0.1	1.1	GO:0043171	peptide catabolic process(GO:0043171)
0.1	1.6	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
0.1	1.2	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	1.7	GO:0071219	cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.1	0.4	GO:0003139	secondary heart field specification(GO:0003139)
0.1	0.6	GO:0097345	mitochondrial outer membrane permeabilization(GO:0097345)
0.1	3.6	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.1	1.3	GO:0007032	endosome organization(GO:0007032)
0.1	15.9	GO:0045087	innate immune response(GO:0045087)
0.1	4.4	GO:0006342	chromatin silencing(GO:0006342)
0.1	2.8	GO:0043406	positive regulation of MAP kinase activity(GO:0043406)
0.1	0.3	GO:0035777	pronephric distal tubule development(GO:0035777)
0.1	4.2	GO:0055113	epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.1	0.5	GO:0097178	ruffle assembly(GO:0097178)
0.1	1.0	GO:0045807	positive regulation of endocytosis(GO:0045807)
0.1	5.8	GO:0048545	response to steroid hormone(GO:0048545)
0.1	1.0	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	1.8	GO:0001649	osteoblast differentiation(GO:0001649)
0.1	3.0	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	2.8	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.1	2.9	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	1.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.5	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.9	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	4.3	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.0	1.2	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.4	GO:0030168	platelet activation(GO:0030168)
0.0	1.1	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.7	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	2.0	GO:0001816	cytokine production(GO:0001816)
0.0	1.9	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0	1.3	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.6	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0	1.9	GO:0071482	cellular response to light stimulus(GO:0071482)
0.0	0.6	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	2.0	GO:0006954	inflammatory response(GO:0006954)
0.0	0.4	GO:0050919	negative chemotaxis(GO:0050919)
0.0	5.4	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	7.6	GO:0006955	immune response(GO:0006955)
0.0	0.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.0	GO:1990120	messenger ribonucleoprotein complex assembly(GO:1990120)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	1.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	1.4	GO:0030838	positive regulation of actin filament polymerization(GO:0030838)
0.0	6.1	GO:0051603	cellular protein catabolic process(GO:0044257) proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0	2.0	GO:0030833	regulation of actin filament polymerization(GO:0030833)
0.0	1.0	GO:0034620	cellular response to unfolded protein(GO:0034620)
0.0	6.0	GO:0006486	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0	1.7	GO:0045765	regulation of angiogenesis(GO:0045765)
0.0	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.4	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
0.0	1.6	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.3	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	1.4	GO:0007422	peripheral nervous system development(GO:0007422)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	1.5	GO:0040008	regulation of growth(GO:0040008)
0.0	4.8	GO:0008283	cell proliferation(GO:0008283)
0.0	1.7	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.7	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.0	7.3	GO:0016567	protein ubiquitination(GO:0016567)
0.0	0.3	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0	0.2	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	11.2	GO:0042612	MHC class I protein complex(GO:0042612)
1.5	6.2	GO:1990909	Wnt signalosome(GO:1990909)
1.2	9.3	GO:0042613	MHC class II protein complex(GO:0042613)
1.1	16.8	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.9	13.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.7	28.7	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.6	2.5	GO:0098842	postsynaptic early endosome(GO:0098842)
0.6	2.3	GO:0060171	stereocilium membrane(GO:0060171)
0.5	3.8	GO:0016234	inclusion body(GO:0016234)
0.3	9.1	GO:0005839	proteasome core complex(GO:0005839)
0.3	4.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	4.8	GO:0000813	ESCRT I complex(GO:0000813)
0.2	6.0	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	3.4	GO:0097651	phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2	2.5	GO:0031010	ISWI-type complex(GO:0031010)
0.2	8.9	GO:0005861	troponin complex(GO:0005861)
0.2	0.9	GO:0030314	junctional membrane complex(GO:0030314)
0.2	0.7	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	1.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	2.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	8.9	GO:0001726	ruffle(GO:0001726)
0.1	12.2	GO:0030018	Z disc(GO:0030018)
0.1	13.7	GO:0005925	focal adhesion(GO:0005925)
0.1	0.4	GO:0043514	interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1	18.7	GO:0031012	extracellular matrix(GO:0031012)
0.1	1.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	5.6	GO:0019814	immunoglobulin complex(GO:0019814)
0.1	13.9	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	0.3	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	5.1	GO:0005884	actin filament(GO:0005884)
0.1	12.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	6.2	GO:0016324	apical plasma membrane(GO:0016324)
0.0	15.8	GO:0000785	chromatin(GO:0000785)
0.0	7.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.5	GO:0016605	PML body(GO:0016605)
0.0	46.5	GO:0005615	extracellular space(GO:0005615)
0.0	1.9	GO:0031901	early endosome membrane(GO:0031901)
0.0	1.4	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	3.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.3	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.3	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	2.6	GO:0010008	endosome membrane(GO:0010008)
0.0	4.4	GO:0005938	cell cortex(GO:0005938)
0.0	5.8	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	73.5	GO:0005634	nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	13.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
2.2	15.3	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
2.1	12.6	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
1.4	21.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
1.4	4.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
1.3	6.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
1.1	7.4	GO:0004126	cytidine deaminase activity(GO:0004126)
1.0	43.9	GO:0048020	CCR chemokine receptor binding(GO:0048020)
1.0	9.7	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.9	31.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.8	8.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.7	2.9	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7	2.0	GO:0003978	UDP-glucose 4-epimerase activity(GO:0003978)
0.7	2.6	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6	2.9	GO:0038131	neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.6	2.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.6	5.0	GO:0004586	ornithine decarboxylase activity(GO:0004586)
0.5	1.6	GO:0004990	oxytocin receptor activity(GO:0004990)
0.5	12.8	GO:0035591	signaling adaptor activity(GO:0035591)
0.5	2.9	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5	9.1	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5	6.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	4.7	GO:0050700	CARD domain binding(GO:0050700)
0.5	13.0	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5	3.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	4.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.4	12.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.4	7.3	GO:0045134	guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.4	9.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.4	1.6	GO:0101006	protein histidine phosphatase activity(GO:0101006)
0.4	2.9	GO:0004984	olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.4	8.1	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.3	9.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.3	3.2	GO:0070700	BMP receptor binding(GO:0070700)
0.2	5.8	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	3.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	5.1	GO:0005523	tropomyosin binding(GO:0005523)
0.2	6.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.2	1.5	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.2	0.5	GO:0031704	apelin receptor binding(GO:0031704)
0.2	3.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	7.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	4.6	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	1.2	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.1	1.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	1.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	4.2	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	18.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	2.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	3.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	0.4	GO:0019972	interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1	3.4	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.1	0.8	GO:0010436	beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1	4.4	GO:0031491	nucleosome binding(GO:0031491)
0.1	6.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	2.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	3.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	1.8	GO:0005112	Notch binding(GO:0005112)
0.1	7.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	9.1	GO:0005125	cytokine activity(GO:0005125)
0.1	13.7	GO:0046982	protein heterodimerization activity(GO:0046982)
0.1	1.9	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.9	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1	21.4	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	1.7	GO:0005518	collagen binding(GO:0005518)
0.1	0.6	GO:0043028	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1	1.7	GO:0051020	GTPase binding(GO:0051020)
0.1	9.2	GO:0043492	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.1	11.5	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.1	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.6	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	16.5	GO:0051015	actin filament binding(GO:0051015)
0.0	6.6	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	1.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.6	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	1.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	2.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	12.7	GO:0003779	actin binding(GO:0003779)
0.0	3.4	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.5	GO:0016408	C-acyltransferase activity(GO:0016408)
0.0	1.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.5	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	52.6	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	1.9	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.2	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.9	GO:0043130	ubiquitin binding(GO:0043130)
0.0	1.0	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0017020	myosin phosphatase regulator activity(GO:0017020)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.5	GO:0004707	MAP kinase activity(GO:0004707)
0.0	1.3	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	2.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	1.9	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.3	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	18.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
1.1	21.1	PID IL23 PATHWAY	IL23-mediated signaling events
1.0	19.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.8	24.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.7	13.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.7	19.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.6	12.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.5	4.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	8.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.4	5.8	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	2.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.2	9.9	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	5.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	8.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	0.8	PID ALK2 PATHWAY	ALK2 signaling events
0.2	2.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.2	2.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	5.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	2.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	1.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	2.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	4.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	4.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	3.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	6.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	1.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	1.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	1.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	2.1	PID BMP PATHWAY	BMP receptor signaling
0.0	6.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	5.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.0	5.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
2.3	16.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
2.2	11.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
1.9	33.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
1.8	10.7	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.2	5.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.8	2.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.8	5.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.6	17.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.6	5.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.6	6.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5	24.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.5	17.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.4	8.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4	4.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.3	8.6	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.3	0.9	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2	6.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	1.9	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	3.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.2	3.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	11.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	2.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	2.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	4.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	2.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	2.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases