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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nfil3-5

Z-value: 1.45

Motif logo

Transcription factors associated with nfil3-5

Gene Symbol Gene ID Gene Info
ENSDARG00000094965 nuclear factor, interleukin 3 regulated, member 5
ENSDARG00000113345 nuclear factor, interleukin 3 regulated, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfil3-5dr11_v1_chr6_+_8172227_81722270.572.8e-09Click!

Activity profile of nfil3-5 motif

Sorted Z-values of nfil3-5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_34984333 32.29 ENSDART00000154760
coiled-coil domain containing 136b
chr21_-_22114625 25.89 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr5_+_37837245 25.46 ENSDART00000171617
ependymin
chr24_-_38079261 23.47 ENSDART00000105662
C-reactive protein 1
chr17_-_43466317 23.12 ENSDART00000155313
heat shock protein 4 like
chr3_-_46818001 22.93 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr14_+_33458294 22.09 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr3_+_16612574 22.07 ENSDART00000104481
solute carrier family 17 (vesicular glutamate transporter), member 7a
chr17_-_20979077 19.73 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr10_-_24371312 19.35 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr7_+_30787903 18.81 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr21_-_22115136 18.80 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
ELMO/CED-12 domain containing 1
chr4_-_5302866 18.48 ENSDART00000138590
si:ch211-214j24.9
chr21_-_42202792 17.83 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr7_+_38717624 17.57 ENSDART00000132522
synaptotagmin XIII
chr3_-_35602233 17.26 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr25_+_15354095 16.95 ENSDART00000090397
KIAA1549-like a
chr23_+_45579497 16.24 ENSDART00000110381
early growth response 4
chr23_+_37323962 16.05 ENSDART00000102881
family with sequence similarity 43, member B
chr25_-_11088839 15.79 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr13_-_21688176 15.73 ENSDART00000063825
shadow of prion protein
chr2_+_24177190 15.42 ENSDART00000099546
microtubule associated protein 4 like
chr16_+_46111849 15.24 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr1_-_14234076 14.69 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr16_+_39146696 14.61 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr21_-_43949208 14.45 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr13_+_27314795 14.42 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr21_-_43550120 14.38 ENSDART00000151627
si:ch73-362m14.2
chr1_-_14233815 14.35 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr19_+_23982466 14.19 ENSDART00000080673
synaptotagmin XIa
chr1_-_8101495 14.18 ENSDART00000161938
si:dkeyp-9d4.3
chr3_-_28665291 13.78 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr11_-_10770053 13.06 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr6_-_13187168 12.92 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr19_-_5254699 12.85 ENSDART00000081951
syntaxin 1B
chr6_+_12326267 12.75 ENSDART00000155101
si:dkey-276j7.3
chr4_-_5302162 12.11 ENSDART00000177099
si:ch211-214j24.9
chr7_+_20535869 11.83 ENSDART00000078181
zgc:158423
chr5_-_55848358 11.74 ENSDART00000130891
calcium/calmodulin-dependent protein kinase IV
chr14_-_21219659 11.74 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr5_-_55848511 11.65 ENSDART00000183503
calcium/calmodulin-dependent protein kinase IV
chr10_-_26729930 11.56 ENSDART00000145532
fibroblast growth factor 13b
chr5_-_21970881 11.22 ENSDART00000182907
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr5_+_1278092 11.08 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr14_-_21618005 11.04 ENSDART00000043162
receptor accessory protein 2
chr8_-_32497815 10.71 ENSDART00000122359
si:dkey-164f24.2
chr6_+_41255485 10.66 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr18_-_21859019 10.60 ENSDART00000100885
neuritin 1-like a
chr1_-_53750522 10.57 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr4_-_22671469 10.47 ENSDART00000050753
CD36 molecule (thrombospondin receptor)
chr25_-_10564721 10.35 ENSDART00000154776
galanin/GMAP prepropeptide
chr10_+_21776911 10.20 ENSDART00000163077
ENSDART00000186093
protocadherin 1 gamma 22
chr9_-_18877597 10.11 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr2_+_34967022 10.10 ENSDART00000134926
astrotactin 1
chr10_-_26738209 10.01 ENSDART00000188590
fibroblast growth factor 13b
chr4_-_5291256 9.80 ENSDART00000150864
si:ch211-214j24.9
chr18_-_1228688 9.79 ENSDART00000064403
neuroplastin b
chr23_+_17800717 9.66 ENSDART00000122654
ENSDART00000044986
Rho family GTPase 1a
chr8_-_32497581 9.40 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr2_+_34967210 9.26 ENSDART00000141796
astrotactin 1
chr6_-_35472923 9.14 ENSDART00000185907
regulator of G protein signaling 8
chr5_+_29784172 8.93 ENSDART00000139035
si:ch211-215c18.3
chr3_+_33345348 8.85 ENSDART00000059262
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr23_+_19590006 8.77 ENSDART00000021231
sarcolemma associated protein b
chr25_+_7784582 8.68 ENSDART00000155016
diacylglycerol kinase, zeta b
chr5_-_22001003 8.66 ENSDART00000134393
ENSDART00000143878
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr12_-_26383242 8.63 ENSDART00000152941
ubiquitin specific peptidase 54b
chr3_+_37827373 8.54 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr7_-_32782430 8.50 ENSDART00000173808
growth arrest-specific 2b
chr8_+_47897734 8.45 ENSDART00000140266
mitofusin 2
chr25_-_10565006 8.40 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr7_-_32833153 8.39 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr14_-_9199968 8.14 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr3_+_15296824 8.07 ENSDART00000043801
calcium binding protein 5b
chr19_+_7549854 8.03 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr25_-_9805269 8.01 ENSDART00000192048
leucine rich repeat containing 4C
chr5_-_40210447 7.92 ENSDART00000131323
si:dkey-193c22.1
chr20_-_40717900 7.89 ENSDART00000181663
connexin 43
chr18_+_1703984 7.86 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr11_+_30161699 7.83 ENSDART00000190504
cyclin-dependent kinase-like 5
chr1_+_31864404 7.81 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr7_-_38861741 7.73 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
PHD finger protein 21Aa
chr9_+_17862858 7.73 ENSDART00000166566
diacylglycerol kinase, eta
chr9_-_18742704 7.58 ENSDART00000145401
TSC22 domain family, member 1
chr9_+_46644633 7.45 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr7_+_26629084 7.41 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr22_-_354592 7.37 ENSDART00000155769
transmembrane protein 240b
chr18_-_898870 7.27 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr10_-_17284055 7.26 ENSDART00000167464
G protein subunit alpha z
chr4_+_3482312 7.13 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr20_+_1121458 6.96 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr14_-_18671334 6.90 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr9_+_17429170 6.87 ENSDART00000006256
zgc:101559
chr6_-_12314475 6.81 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
chr13_-_27675212 6.81 ENSDART00000141035
regulating synaptic membrane exocytosis 1a
chr19_-_28367413 6.77 ENSDART00000079092
si:dkey-261i16.5
chr14_+_36628131 6.68 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr24_-_17023392 6.67 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr6_+_8172227 6.58 ENSDART00000146106
nuclear factor, interleukin 3 regulated, member 5
chr15_-_9272328 6.56 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr19_-_12145765 6.49 ENSDART00000032474
poly A binding protein, cytoplasmic 1 b
chr23_-_5032587 6.46 ENSDART00000163903
potassium voltage-gated channel, shaker-related subfamily, member 2b
chr21_-_42007213 6.44 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr6_-_21616659 6.28 ENSDART00000074256
protein phosphatase 1, regulatory subunit 12C
chr5_-_41494831 6.28 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr7_+_38278860 6.19 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr4_-_40972176 6.05 ENSDART00000152052
si:dkeyp-82h4.1
chr11_+_6819050 6.03 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr22_+_786556 6.01 ENSDART00000125347
cryptochrome circadian clock 1bb
chr15_-_26636826 6.01 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr1_+_54673846 5.97 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr16_-_21047872 5.88 ENSDART00000131582
chromobox homolog 3b
chr9_-_18743012 5.81 ENSDART00000131626
TSC22 domain family, member 1
chr12_+_36416173 5.74 ENSDART00000190278
unkempt family zinc finger
chr21_-_12119711 5.69 ENSDART00000131538
CUGBP, Elav-like family member 4
chr20_-_44576949 5.66 ENSDART00000148639
UBX domain protein 2A
chr5_-_30704390 5.64 ENSDART00000016709
intraflagellar transport 22 homolog (Chlamydomonas)
chr15_+_7992906 5.61 ENSDART00000090790
cell adhesion molecule 2b
chr6_-_29612269 5.54 ENSDART00000104293
peroxisomal biogenesis factor 5-like a
chr11_+_30161168 5.51 ENSDART00000157385
cyclin-dependent kinase-like 5
chr16_-_45069882 5.50 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_-_50638905 5.49 ENSDART00000180842
multiple C2 domains, transmembrane 1a
chr22_-_3595439 5.48 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr19_-_12145390 5.44 ENSDART00000143087
poly A binding protein, cytoplasmic 1 b
chr20_+_38201644 5.40 ENSDART00000022694
EH-domain containing 3
chr6_-_18121075 5.40 ENSDART00000171072
si:dkey-237i9.1
chr3_-_21348478 5.40 ENSDART00000114906
family with sequence similarity 171, member A2a
chr8_-_39903803 5.37 ENSDART00000012391
calcium binding protein 1a
chr18_+_17428506 5.33 ENSDART00000100223
zgc:91860
chr19_-_41371978 5.33 ENSDART00000166063
ENSDART00000170343
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr5_+_38276582 5.17 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_16600690 5.13 ENSDART00000162164
microtubule associated tumor suppressor 1b
chr18_-_39288894 5.07 ENSDART00000186216
mitogen-activated protein kinase 6
chr8_+_25761654 5.07 ENSDART00000137899
ENSDART00000062403
transmembrane protein 9
chr23_+_19590598 5.04 ENSDART00000170149
sarcolemma associated protein b
chr20_-_36617313 5.01 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr16_+_28270037 4.98 ENSDART00000059035
MINDY lysine 48 deubiquitinase 3
chr11_-_7078392 4.93 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
chr19_+_21362553 4.86 ENSDART00000122002
teashirt zinc finger homeobox 1
chr21_+_11923701 4.85 ENSDART00000109292
ubiquitin associated protein 2a
chr25_+_36152215 4.82 ENSDART00000036147
iroquois homeobox 5b
chr7_+_22801465 4.76 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr4_+_5333988 4.73 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
APEX nuclease (multifunctional DNA repair enzyme) 1
chr15_+_17321218 4.72 ENSDART00000143796
clathrin, heavy chain b (Hc)
chr2_-_32486080 4.70 ENSDART00000110821
tetratricopeptide repeat domain 19
chr12_+_15002757 4.69 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr11_+_714386 4.63 ENSDART00000167824
ENSDART00000187110
TIMP metallopeptidase inhibitor 4, tandem duplicate 3
chr5_+_15350954 4.59 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr21_-_21148623 4.56 ENSDART00000184364
ankyrin 1, erythrocytic b
chr11_+_16153207 4.55 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr7_-_6604623 4.53 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr3_-_1204341 4.49 ENSDART00000089646
family with sequence similarity 234, member B
chr19_-_20093341 4.43 ENSDART00000129917
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr15_-_16121496 4.42 ENSDART00000128624
uncharacterized serine/threonine-protein kinase SgK494a
chr9_-_43375205 4.41 ENSDART00000138436
zinc finger protein 385B
chr3_-_33880951 4.32 ENSDART00000013228
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr5_+_32007627 4.29 ENSDART00000183061
suppressor of cancer cell invasion
chr9_-_10532591 4.26 ENSDART00000175269
thrombospondin, type I, domain containing 7Ba
chr21_-_32467799 4.24 ENSDART00000007675
ENSDART00000133099
zgc:123105
chr7_-_67842997 4.22 ENSDART00000169763
polyamine modulated factor 1 binding protein 1
chr21_+_5915041 4.20 ENSDART00000151370
proline dehydrogenase (oxidase) 1a
chr14_+_45406299 4.16 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr22_+_4488454 4.14 ENSDART00000170620
cortexin 1
chr22_-_3449282 4.12 ENSDART00000136798
protein tyrosine phosphatase, receptor type, s, a
chr16_+_29043813 4.02 ENSDART00000122681
nestin
chr6_-_53282572 3.96 ENSDART00000172615
ENSDART00000165036
RNA binding motif protein 5
chr8_+_8712446 3.95 ENSDART00000158674
ELK1, member of ETS oncogene family
chr6_-_30658755 3.88 ENSDART00000065215
ENSDART00000181302
leucine rich adaptor protein 1
chr25_-_16826219 3.86 ENSDART00000191299
ENSDART00000188504
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr1_-_5394752 3.85 ENSDART00000103724
ENSDART00000188453
Nedd4 family interacting protein 2
chr14_+_34971554 3.85 ENSDART00000184271
ring finger protein 145a
chr7_+_17716601 3.76 ENSDART00000173792
ENSDART00000080825
reticulon 3
chr4_+_5334439 3.75 ENSDART00000180644
APEX nuclease (multifunctional DNA repair enzyme) 1
chr9_-_34509997 3.73 ENSDART00000169114
protein phosphatase 2, regulatory subunit B'', beta
chr11_-_3954691 3.73 ENSDART00000182041
polybromo 1
chr15_-_22074315 3.72 ENSDART00000149830
dopamine receptor D2a
chr5_-_21030934 3.71 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr15_+_24737599 3.68 ENSDART00000078024
v-crk avian sarcoma virus CT10 oncogene homolog
chr7_+_21887307 3.62 ENSDART00000052871
POP7 homolog, ribonuclease P/MRP subunit
chr16_+_10841163 3.57 ENSDART00000065467
death effector domain-containing 1
chr24_+_26406770 3.56 ENSDART00000110011
si:ch211-230g15.5
chr16_-_21047483 3.55 ENSDART00000136235
chromobox homolog 3b
chr7_+_46252993 3.54 ENSDART00000167149
zinc finger protein 536
chr2_-_33687214 3.54 ENSDART00000147439
ATPase H+ transporting V0 subunit b
chr15_-_19128705 3.44 ENSDART00000152428
Rho GTPase activating protein 32a
chr24_-_23323526 3.43 ENSDART00000112256
ENSDART00000176903
zinc finger homeobox 4
chr18_+_924949 3.42 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr10_+_33895315 3.42 ENSDART00000142881
furry homolog b (Drosophila)
chr6_-_19683406 3.40 ENSDART00000158041
cilia and flagella associated protein 52
chr14_-_24095414 3.40 ENSDART00000172747
ENSDART00000173146
si:ch211-277c7.7
chr16_-_31790285 3.36 ENSDART00000184655
chromodomain helicase DNA binding protein 4b
chr1_-_45039726 3.27 ENSDART00000186188
SMU1, DNA replication regulator and spliceosomal factor b
chr7_-_26457208 3.24 ENSDART00000173519
zgc:172079
chr9_-_34500197 3.24 ENSDART00000114043
protein phosphatase 2, regulatory subunit B'', beta
chr15_-_28480546 3.15 ENSDART00000057696
ENSDART00000160858
G protein-coupled receptor kinase interacting ArfGAP 1
chr2_-_29485408 3.12 ENSDART00000013411
carbonic anhydrase
chr21_-_32467099 3.10 ENSDART00000186354
zgc:123105
chr21_-_39566854 3.03 ENSDART00000020174
dynein, light chain, LC8-type 2b
chr17_-_8268406 2.99 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
Abelson helper integration site 1
chr16_+_22865942 2.97 ENSDART00000103235
ENSDART00000143957
flavin adenine dinucleotide synthetase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 30.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
3.7 14.6 GO:0060074 synapse maturation(GO:0060074)
2.5 32.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
2.3 9.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
2.0 6.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.8 9.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.7 5.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.6 17.3 GO:0050909 sensory perception of taste(GO:0050909)
1.5 21.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.3 6.4 GO:0070208 protein heterotrimerization(GO:0070208)
1.2 8.4 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
1.2 11.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.2 10.5 GO:0044539 long-chain fatty acid import(GO:0044539)
1.1 8.0 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.1 19.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.0 4.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
1.0 3.0 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
1.0 17.8 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
1.0 5.9 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.9 11.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.9 2.7 GO:0006089 lactate metabolic process(GO:0006089)
0.9 20.5 GO:0015701 bicarbonate transport(GO:0015701)
0.8 4.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.8 10.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.8 4.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.8 2.4 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.8 3.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.8 4.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 33.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.7 16.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.7 7.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.7 9.6 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.7 2.0 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.7 7.4 GO:0034605 cellular response to heat(GO:0034605)
0.7 2.0 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.7 13.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.6 4.5 GO:0036268 swimming(GO:0036268)
0.6 2.6 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.6 12.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.6 2.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.6 2.8 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.6 1.7 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.5 5.3 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.5 2.6 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.5 2.0 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.5 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.5 6.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 8.5 GO:0051764 actin crosslink formation(GO:0051764)
0.5 10.1 GO:0080111 DNA demethylation(GO:0080111)
0.5 4.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 2.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.4 1.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.4 2.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 2.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 5.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.4 3.9 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.3 2.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 1.0 GO:0036076 ligamentous ossification(GO:0036076)
0.3 9.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.3 1.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 5.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 20.7 GO:0006414 translational elongation(GO:0006414)
0.3 2.8 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.3 6.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 19.0 GO:0015914 phospholipid transport(GO:0015914)
0.3 0.9 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 2.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 2.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735) pronephric proximal tubule development(GO:0035776)
0.3 23.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.3 1.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 31.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.3 9.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 8.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.3 0.8 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3 8.1 GO:0046847 filopodium assembly(GO:0046847)
0.3 3.0 GO:0044458 motile cilium assembly(GO:0044458)
0.3 5.3 GO:0048667 cell morphogenesis involved in neuron differentiation(GO:0048667)
0.3 1.8 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 0.9 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.2 2.9 GO:0006020 inositol metabolic process(GO:0006020)
0.2 14.5 GO:0003146 heart jogging(GO:0003146)
0.2 2.2 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 4.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.8 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) dGDP metabolic process(GO:0046066)
0.2 1.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 1.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.2 2.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 1.9 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.2 7.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 6.3 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.2 0.9 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 2.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 3.7 GO:0007520 myoblast fusion(GO:0007520)
0.2 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 40.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 1.6 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 4.8 GO:0043967 histone H4 acetylation(GO:0043967)
0.2 6.3 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.2 11.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 1.7 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.2 28.5 GO:0006814 sodium ion transport(GO:0006814)
0.2 3.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 4.8 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 1.0 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.1 2.8 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.7 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 4.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 2.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.7 GO:0031643 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.1 5.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 4.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 12.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.2 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.1 4.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 9.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 0.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 5.0 GO:0006757 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.1 3.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 10.0 GO:0021782 glial cell development(GO:0021782)
0.1 1.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 6.5 GO:0001933 negative regulation of protein phosphorylation(GO:0001933)
0.1 1.8 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.7 GO:0032543 mitochondrial translation(GO:0032543)
0.1 3.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 10.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.9 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 6.1 GO:0048066 developmental pigmentation(GO:0048066)
0.1 2.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 20.5 GO:0050767 regulation of neurogenesis(GO:0050767)
0.1 8.9 GO:0030334 regulation of cell migration(GO:0030334)
0.1 25.9 GO:0031175 neuron projection development(GO:0031175)
0.1 4.0 GO:0006865 amino acid transport(GO:0006865)
0.1 10.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 1.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 5.8 GO:0006936 muscle contraction(GO:0006936)
0.0 1.1 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488)
0.0 2.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.0 GO:0072175 epithelial tube formation(GO:0072175)
0.0 0.6 GO:0007631 feeding behavior(GO:0007631)
0.0 7.1 GO:0099537 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0 1.6 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 3.6 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 9.8 GO:0001944 vasculature development(GO:0001944)
0.0 6.5 GO:0008380 RNA splicing(GO:0008380)
0.0 1.4 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 3.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 1.7 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.9 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0032839 dendrite cytoplasm(GO:0032839)
2.2 22.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
2.0 30.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.6 7.8 GO:0005883 neurofilament(GO:0005883)
1.0 6.0 GO:0070062 extracellular exosome(GO:0070062)
1.0 12.8 GO:0033270 paranode region of axon(GO:0033270)
0.9 4.7 GO:0071439 clathrin complex(GO:0071439)
0.9 29.0 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.8 11.0 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.8 4.2 GO:0097224 sperm connecting piece(GO:0097224)
0.8 6.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.6 12.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.6 2.5 GO:0097268 cytoophidium(GO:0097268)
0.6 18.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 36.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 8.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.5 9.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.5 4.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 3.4 GO:0001650 fibrillar center(GO:0001650)
0.5 3.7 GO:0016586 RSC complex(GO:0016586)
0.4 7.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 5.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 2.0 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 8.0 GO:0060170 ciliary membrane(GO:0060170)
0.4 60.6 GO:0070382 exocytic vesicle(GO:0070382)
0.4 1.1 GO:0031251 PAN complex(GO:0031251)
0.4 21.6 GO:0030426 growth cone(GO:0030426)
0.4 6.8 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.3 14.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.3 20.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 10.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 17.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 30.7 GO:0014069 postsynaptic density(GO:0014069)
0.3 3.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 10.5 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 2.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 4.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 3.4 GO:0030427 site of polarized growth(GO:0030427)
0.2 7.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.1 GO:0035517 PR-DUB complex(GO:0035517)
0.1 3.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 16.8 GO:0016607 nuclear speck(GO:0016607)
0.1 1.8 GO:0048179 activin receptor complex(GO:0048179)
0.1 2.0 GO:0005869 dynactin complex(GO:0005869)
0.1 3.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 4.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 8.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 55.3 GO:0043005 neuron projection(GO:0043005)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 16.9 GO:0005764 lysosome(GO:0005764)
0.1 1.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 5.7 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0008278 cohesin complex(GO:0008278)
0.0 2.3 GO:0008305 integrin complex(GO:0008305)
0.0 1.4 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 4.6 GO:0005884 actin filament(GO:0005884)
0.0 2.7 GO:0070469 respiratory chain(GO:0070469)
0.0 5.6 GO:0099568 cytoplasmic region(GO:0099568)
0.0 3.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 12.3 GO:0005768 endosome(GO:0005768)
0.0 8.9 GO:0005929 cilium(GO:0005929)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 19.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
2.6 10.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
2.3 30.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
2.0 10.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
1.9 5.7 GO:1990715 mRNA CDS binding(GO:1990715)
1.7 24.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
1.5 70.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.4 5.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.3 9.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.0 4.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.0 3.0 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
1.0 4.8 GO:0050699 WW domain binding(GO:0050699)
0.9 13.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.9 7.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.9 13.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 5.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.8 21.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 18.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.7 7.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.7 2.9 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.7 15.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.7 8.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.7 16.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.7 4.0 GO:0019215 intermediate filament binding(GO:0019215)
0.7 14.6 GO:0019894 kinesin binding(GO:0019894)
0.6 2.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 2.5 GO:0003883 CTP synthase activity(GO:0003883)
0.6 30.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.6 14.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.6 3.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 2.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.5 2.0 GO:0044548 S100 protein binding(GO:0044548)
0.5 5.0 GO:0005522 profilin binding(GO:0005522)
0.5 20.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 4.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 5.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 6.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.4 1.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.4 4.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 5.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 2.7 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.3 4.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 1.2 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.3 2.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 9.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 2.2 GO:0015232 heme transporter activity(GO:0015232)
0.3 3.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 1.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 4.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 2.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 2.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 2.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 23.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.2 6.9 GO:0004707 MAP kinase activity(GO:0004707)
0.2 5.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 2.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 9.1 GO:0005178 integrin binding(GO:0005178)
0.2 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.5 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 6.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 7.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 48.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 49.0 GO:0003924 GTPase activity(GO:0003924)
0.1 1.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 3.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 5.1 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 4.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 2.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 12.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 23.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 11.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.8 GO:0044325 ion channel binding(GO:0044325)
0.1 1.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 11.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.1 4.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 4.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 17.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 1.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 8.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.4 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.9 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 35.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.8 7.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.7 20.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.5 3.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 10.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 8.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 4.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.6 PID AURORA B PATHWAY Aurora B signaling
0.1 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 2.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.4 23.4 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.9 10.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 3.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.5 12.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.5 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 10.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 7.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 6.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.4 5.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 2.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 3.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.3 7.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 3.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 2.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 2.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 2.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 9.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 5.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 4.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes