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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nfil3-4+si:dkey-172o19.2

Z-value: 1.17

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Transcription factors associated with nfil3-4+si:dkey-172o19.2

Gene Symbol Gene ID Gene Info
ENSDARG00000071398 si_dkey-172o19.2
ENSDARG00000092346 nuclear factor, interleukin 3 regulated, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-172o19.2dr11_v1_chr22_+_20546612_205466120.161.1e-01Click!
nfil3-4dr11_v1_chr22_+_20560041_205600410.141.9e-01Click!

Activity profile of nfil3-4+si:dkey-172o19.2 motif

Sorted Z-values of nfil3-4+si:dkey-172o19.2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_26310854 9.50 ENSDART00000080113
apolipoprotein Db
chr4_-_12725513 8.27 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr25_-_13188678 7.26 ENSDART00000125754
si:ch211-147m6.1
chr5_+_29831235 7.25 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr1_-_10071422 6.35 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr9_-_45602978 6.18 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr11_+_25278772 6.12 ENSDART00000188630
cylindromatosis (turban tumor syndrome), b
chr14_+_21107032 6.12 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr3_+_49043917 5.96 ENSDART00000158212
zgc:92161
chr18_-_5598958 5.91 ENSDART00000161538
cytochrome P450, family 1, subfamily A
chr14_+_21106444 5.85 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr24_-_26328721 5.78 ENSDART00000125468
apolipoprotein Db
chr1_+_14253118 5.63 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr25_-_8602437 5.51 ENSDART00000171200
Rh family, C glycoprotein b
chr11_+_43419809 5.46 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr18_-_7143920 5.25 ENSDART00000135587
CD9 molecule a
chr17_+_26965351 5.12 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr6_+_42475730 5.12 ENSDART00000150226
macrophage stimulating 1 receptor a
chr5_-_30615901 5.08 ENSDART00000147769
si:ch211-117m20.5
chr14_+_3507326 5.06 ENSDART00000159326
glutathione S-transferase pi 1
chr8_-_36287046 5.03 ENSDART00000162877
si:busm1-194e12.11
chr11_-_6265574 4.96 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr7_-_24364536 4.90 ENSDART00000064789
thioredoxin
chr5_+_4332220 4.87 ENSDART00000051699
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr14_+_1170968 4.85 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr13_+_33688474 4.83 ENSDART00000161465

chr14_-_12071679 4.77 ENSDART00000165581
thymosin beta 1
chr5_+_57658898 4.74 ENSDART00000074268
ENSDART00000124568
zgc:153929
chr20_-_26551210 4.72 ENSDART00000077715
si:dkey-25e12.3
chr14_+_48862987 4.69 ENSDART00000167810
zgc:154054
chr14_-_12071447 4.68 ENSDART00000166116
thymosin beta 1
chr7_-_3429874 4.67 ENSDART00000132330
si:ch211-285c6.1
chr5_+_45677781 4.65 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr14_+_4151379 4.56 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr22_+_10606573 4.55 ENSDART00000192638
RAD54 like 2
chr19_+_5674907 4.52 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr18_+_13162728 4.52 ENSDART00000101472
tyrosine aminotransferase
chr15_-_29348212 4.49 ENSDART00000133117
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr22_+_10606863 4.43 ENSDART00000147975
RAD54 like 2
chr16_-_19568388 4.35 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr22_+_5478353 4.28 ENSDART00000160596
tubulin polymerization promoting protein
chr13_-_25750910 4.25 ENSDART00000111567
sphingosine-1-phosphate lyase 1
chr2_-_20923864 4.23 ENSDART00000006870
prostaglandin-endoperoxide synthase 2a
chr8_-_39739627 4.22 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr14_+_11430796 4.19 ENSDART00000165275
si:ch211-153b23.3
chr18_-_7539166 4.15 ENSDART00000133541
si:dkey-30c15.2
chr25_+_13191391 4.15 ENSDART00000109937
si:ch211-147m6.2
chr16_+_40954481 4.09 ENSDART00000058587
glycogen synthase kinase binding protein
chr24_+_38671054 4.07 ENSDART00000154214
si:ch73-70c5.1
chr7_+_21787507 4.07 ENSDART00000100936
transmembrane protein 88 b
chr10_-_22095505 4.06 ENSDART00000140210
plac8 onzin related protein 10
chr13_-_20540790 4.03 ENSDART00000131467
si:ch1073-126c3.2
chr17_-_2039511 3.99 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr5_-_65037525 3.95 ENSDART00000158856
annexin A1b
chr9_-_48736388 3.95 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr8_-_36475328 3.90 ENSDART00000048448
si:busm1-266f07.2
chr3_-_16142057 3.89 ENSDART00000016616
ADP-ribosylation factor-like 5C
chr24_-_2843107 3.87 ENSDART00000165290
cytochrome b5 type A (microsomal)
chr7_+_30392613 3.85 ENSDART00000075508
lipase, hepatic a
chr11_-_8167799 3.85 ENSDART00000133574
ENSDART00000024046
ENSDART00000146940
urate oxidase
chr5_-_65037371 3.84 ENSDART00000170560
annexin A1b
chr16_+_23984755 3.83 ENSDART00000145328
apolipoprotein C-II
chr22_+_11775269 3.82 ENSDART00000140272
keratin 96
chr14_+_16345003 3.81 ENSDART00000003040
ENSDART00000165193
intelectin 3
chr3_-_50139860 3.80 ENSDART00000101563
bloodthirsty-related gene family, member 2
chr25_+_13191615 3.75 ENSDART00000168849
si:ch211-147m6.2
chr9_-_16109001 3.73 ENSDART00000053473
uridine phosphorylase 2
chr11_-_23501467 3.69 ENSDART00000169066
pleckstrin homology domain containing, family A member 6
chr8_-_21103041 3.68 ENSDART00000171771
ENSDART00000131322
ENSDART00000137838
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr3_+_30921246 3.66 ENSDART00000076850
claudin i
chr6_+_9130989 3.62 ENSDART00000162588
regucalcin
chr16_+_50289916 3.61 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr13_-_31008275 3.59 ENSDART00000139394
WDFY family member 4
chr2_-_39017838 3.58 ENSDART00000048838
retinol binding protein 2b, cellular
chr23_-_23401305 3.57 ENSDART00000078936
hairy-related 9
chr5_-_69948099 3.54 ENSDART00000034639
ENSDART00000191111
UDP glucuronosyltransferase 2 family, polypeptide A4
chr22_+_22004082 3.54 ENSDART00000148375
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2
chr13_-_25774183 3.51 ENSDART00000046981
PDZ and LIM domain 1 (elfin)
chr16_+_46410520 3.50 ENSDART00000131072
rapunzel 2
chr17_+_27456804 3.48 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr22_-_13165186 3.47 ENSDART00000105762
aryl hydrocarbon receptor 2
chr13_+_7387822 3.47 ENSDART00000148240
exocyst complex component 3-like 4
chr16_+_23398369 3.46 ENSDART00000037694
S100 calcium binding protein A10b
chr7_+_56577522 3.46 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr20_+_25563105 3.37 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr5_-_55560937 3.36 ENSDART00000148436
guanine nucleotide binding protein (G protein), alpha 14
chr15_+_19838458 3.35 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr7_+_48761875 3.34 ENSDART00000003690
aggrecan a
chr18_+_13164325 3.33 ENSDART00000189057
tyrosine aminotransferase
chr12_-_9132682 3.33 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr24_-_23784701 3.32 ENSDART00000090368
serum/glucocorticoid regulated kinase family, member 3
chr12_-_20373058 3.31 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr5_-_26181863 3.27 ENSDART00000098500
coiled-coil domain containing 125
chr22_-_15593824 3.25 ENSDART00000123125
tropomyosin 4a
chr16_+_23397785 3.22 ENSDART00000148961
S100 calcium binding protein A10b
chr11_+_25504215 3.22 ENSDART00000154213
transcription factor binding to IGHM enhancer 3b
chr3_-_53465223 3.20 ENSDART00000057123
ENSDART00000125515
ENSDART00000143096
nuclear receptor subfamily 5, group A, member 5
chr16_+_29492749 3.20 ENSDART00000179680
cathepsin K
chr16_+_21801277 3.18 ENSDART00000088407
tripartite motif containing 108
chr16_+_23487051 3.16 ENSDART00000145496
ictacalcin 2
chr17_-_20236228 3.15 ENSDART00000136490
ENSDART00000029380
BCL2 interacting protein 4
chr5_-_2112030 3.15 ENSDART00000091932
glucuronidase, beta
chr22_-_24297510 3.14 ENSDART00000163297
si:ch211-117l17.6
chr2_+_10134345 3.13 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr14_+_21699129 3.09 ENSDART00000073707
syntaxin 3A
chr4_-_20181964 3.08 ENSDART00000022539
fibrinogen-like 2a
chr5_+_2815021 3.08 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr4_-_27099224 3.08 ENSDART00000048383
cysteine-rich with EGF-like domains 2
chr2_+_24762567 3.08 ENSDART00000078866
interferon, gamma-inducible protein 30
chr7_+_38380135 3.07 ENSDART00000174005
rhophilin, Rho GTPase binding protein 2
chr10_-_21941443 3.05 ENSDART00000174954

chr8_-_21103522 3.04 ENSDART00000100283
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr22_-_10121880 3.02 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr19_-_15281996 3.02 ENSDART00000103784
endothelin 2
chr18_+_48802154 3.02 ENSDART00000191403
bone morphogenetic protein 16
chr2_+_26288301 3.00 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr13_-_36034582 2.99 ENSDART00000133565
si:dkey-157l19.2
chr20_-_30900947 2.99 ENSDART00000153419
ENSDART00000062536
heme binding protein 2
chr20_-_25533739 2.98 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr25_+_14398650 2.96 ENSDART00000130548
cytokine induced apoptosis inhibitor 1
chr22_+_980290 2.93 ENSDART00000065377
differentially expressed in FDCP 6b homolog (mouse)
chr17_-_6076266 2.89 ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr2_+_20793982 2.89 ENSDART00000014785
proteoglycan 4a
chr8_+_21225064 2.88 ENSDART00000129210
cryptochrome circadian clock 1ba
chr6_+_36381709 2.87 ENSDART00000004727
Rh family, C glycoprotein, like 1
chr23_+_5108374 2.86 ENSDART00000114263
zgc:194242
chr12_-_5120339 2.84 ENSDART00000168759
retinol binding protein 4, plasma
chr25_+_6122823 2.84 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr25_-_29415369 2.82 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr3_+_34670076 2.81 ENSDART00000133457
distal-less homeobox 4a
chr3_-_26017592 2.80 ENSDART00000030890
heme oxygenase 1a
chr5_-_48680580 2.80 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr1_-_20928772 2.77 ENSDART00000078277
methylsterol monooxygenase 1
chr7_+_15736230 2.75 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr22_-_37686966 2.74 ENSDART00000192217
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr13_+_7049823 2.74 ENSDART00000178997
ENSDART00000161443
ribonuclease T2
chr2_+_43920461 2.73 ENSDART00000123673
si:ch211-195h23.3
chr1_-_39895859 2.72 ENSDART00000135791
ENSDART00000035739
transmembrane protein 134
chr3_+_4403980 2.70 ENSDART00000156881

chr5_-_30074332 2.69 ENSDART00000147963
beta-carotene oxygenase 2a
chr20_-_25522911 2.68 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr7_-_19168375 2.67 ENSDART00000112447
interleukin 13 receptor, alpha 1
chr21_-_17956416 2.67 ENSDART00000026737
syntaxin 2a
chr5_+_27421025 2.66 ENSDART00000098590
cytochrome b561 family, member A3a
chr7_+_48761646 2.66 ENSDART00000017467
aggrecan a
chr25_+_32473433 2.65 ENSDART00000152326
sulfide quinone oxidoreductase
chr8_-_41228530 2.65 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr5_-_12587053 2.65 ENSDART00000162780
V-set and immunoglobulin domain containing 10
chr1_+_25696798 2.64 ENSDART00000054228
lecithin retinol acyltransferase a
chr1_-_18615063 2.63 ENSDART00000014916
Kruppel-like factor 3 (basic)
chr15_-_35960250 2.63 ENSDART00000186765
collagen, type IV, alpha 4
chr5_+_26121393 2.61 ENSDART00000002221
beta-carotene 15, 15-dioxygenase 2, like
chr8_-_11324143 2.60 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr7_-_25133783 2.60 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
BCL2 associated agonist of cell death b
chr5_+_37091626 2.59 ENSDART00000161054
transgelin 2
chr9_+_41224100 2.58 ENSDART00000141792
signal transducer and activator of transcription 1b
chr11_+_20896122 2.58 ENSDART00000162339
ENSDART00000181111

chr2_-_55337585 2.57 ENSDART00000177924
tropomyosin 4b
chr12_+_5708400 2.57 ENSDART00000017191
distal-less homeobox 3b
chr1_-_59240975 2.56 ENSDART00000166170
multivesicular body subunit 12A
chr22_+_1796057 2.54 ENSDART00000170834
zinc finger protein 1179
chr6_-_14010554 2.53 ENSDART00000004656
zgc:92027
chr1_-_2457546 2.53 ENSDART00000103795
gamma-glutamylamine cyclotransferase, tandem duplicate 1
chr3_+_16922226 2.53 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr16_+_11834516 2.52 ENSDART00000146611
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr15_+_41919484 2.48 ENSDART00000099821
ENSDART00000146246
NACHT, LRR and PYD domains-containing protein 16
chr1_+_11659861 2.48 ENSDART00000054787

chr2_-_41861040 2.48 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr7_-_39552314 2.46 ENSDART00000134174
solute carrier family 22, member 18
chr12_-_25294769 2.45 ENSDART00000153306
hydroxycarboxylic acid receptor 1-4
chr20_-_40755614 2.44 ENSDART00000061247
connexin 32.3
chr19_-_30811161 2.44 ENSDART00000103524
MYCL proto-oncogene, bHLH transcription factor b
chr20_-_27733683 2.43 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr7_-_3894831 2.43 ENSDART00000172921
si:dkey-88n24.11
chr7_+_19424857 2.42 ENSDART00000173674
si:ch211-212k18.6
chr12_-_5120175 2.41 ENSDART00000160729
retinol binding protein 4, plasma
chr2_+_35595454 2.41 ENSDART00000098734
calcyclin binding protein
chr7_+_56577906 2.38 ENSDART00000184023
haptoglobin
chr8_-_30791266 2.38 ENSDART00000062220
glutathione S-transferase theta 1a
chr17_+_45648836 2.37 ENSDART00000155037
zgc:162184
chr7_+_39706004 2.36 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr16_+_23984179 2.36 ENSDART00000175879
apolipoprotein C-II
chr25_-_26833100 2.35 ENSDART00000014052
nei-like DNA glycosylase 1
chr11_+_37265692 2.34 ENSDART00000184691
interleukin 17 receptor C
chr3_-_26017831 2.34 ENSDART00000179982
heme oxygenase 1a
chr19_+_14113886 2.33 ENSDART00000169343
keratinocyte differentiation factor 1b
chr18_+_12655766 2.33 ENSDART00000144246
thromboxane A synthase 1 (platelet)
chr19_-_977849 2.32 ENSDART00000172303

chr21_-_13668358 2.31 ENSDART00000180323
patatin-like phospholipase domain containing 7a
chr22_-_26175237 2.31 ENSDART00000108737
complement component c3b, tandem duplicate 2
chr2_-_127945 2.30 ENSDART00000056453
insulin-like growth factor binding protein 1b
chr20_-_9760424 2.30 ENSDART00000104936
si:dkey-63j12.4
chr7_+_3597413 2.29 ENSDART00000064281
si:dkey-192d15.2
chr3_-_50147160 2.28 ENSDART00000191341
bloodthirsty-related gene family, member 2
chr16_+_46725087 2.28 ENSDART00000008920
RAB11a, member RAS oncogene family, like
chr2_+_17055069 2.27 ENSDART00000115078
thrombopoietin
chr16_+_32029090 2.27 ENSDART00000041054
transmembrane channel-like 4
chr23_+_19814371 2.26 ENSDART00000182897
emerin (Emery-Dreifuss muscular dystrophy)
chr18_+_2228737 2.25 ENSDART00000165301
RAB27A, member RAS oncogene family
chr25_+_24616717 2.25 ENSDART00000089113
ankyrin repeat and BTB (POZ) domain containing 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-4+si:dkey-172o19.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
1.8 10.9 GO:0006572 tyrosine catabolic process(GO:0006572)
1.7 5.1 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
1.7 5.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.6 4.7 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.5 4.4 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
1.3 7.8 GO:0033028 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.3 3.8 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
1.3 8.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.3 3.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
1.2 4.9 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
1.2 12.1 GO:0042989 sequestering of actin monomers(GO:0042989)
1.2 9.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.1 4.5 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
1.1 3.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.1 4.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.0 6.0 GO:0003151 outflow tract morphogenesis(GO:0003151)
1.0 2.9 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
1.0 3.9 GO:1903292 protein localization to Golgi membrane(GO:1903292)
1.0 7.6 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.9 1.9 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.9 2.6 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.9 2.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.8 4.0 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.8 0.8 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.8 3.8 GO:0046655 folic acid metabolic process(GO:0046655)
0.8 3.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.8 5.3 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.8 3.0 GO:0060471 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.7 4.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.7 2.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.7 2.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.7 10.8 GO:0042574 retinal metabolic process(GO:0042574)
0.7 2.0 GO:0003156 regulation of organ formation(GO:0003156)
0.6 1.9 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.6 1.9 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.6 8.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.6 1.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 2.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.6 1.8 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.6 8.2 GO:0050892 intestinal absorption(GO:0050892)
0.6 1.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.5 2.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.5 1.6 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.5 2.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.5 5.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.5 3.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.5 3.6 GO:0032570 response to progesterone(GO:0032570)
0.5 1.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.5 1.5 GO:0006953 acute-phase response(GO:0006953)
0.5 3.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.5 3.4 GO:0021885 forebrain cell migration(GO:0021885)
0.5 15.3 GO:0007568 aging(GO:0007568)
0.5 2.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5 1.8 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.4 3.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.4 6.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 5.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.4 2.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 1.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 2.0 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.4 4.0 GO:0032262 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.4 39.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.4 1.6 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.4 1.5 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.4 3.7 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.3 3.5 GO:0051601 exocyst localization(GO:0051601)
0.3 5.9 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.3 1.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 2.0 GO:0070285 pigment cell development(GO:0070285)
0.3 1.3 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.3 4.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.3 1.6 GO:0090527 actin filament reorganization(GO:0090527)
0.3 5.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.3 8.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.3 0.6 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.3 3.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.3 1.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 1.2 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.3 0.3 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.3 0.9 GO:0032239 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.3 4.5 GO:0016075 rRNA catabolic process(GO:0016075)
0.3 0.8 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.3 10.4 GO:0030199 collagen fibril organization(GO:0030199)
0.3 4.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 6.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 5.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 0.8 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.3 1.0 GO:0099625 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.3 2.6 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.3 1.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.2 2.7 GO:0042493 response to drug(GO:0042493)
0.2 1.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.2 1.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 4.7 GO:0051180 vitamin transport(GO:0051180)
0.2 1.0 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 2.2 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.5 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.9 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.2 0.9 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 4.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.6 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.2 1.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 1.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 2.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 2.5 GO:0045851 phagolysosome assembly(GO:0001845) vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 0.6 GO:0006004 fucose metabolic process(GO:0006004)
0.2 2.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 1.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.9 GO:0030329 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 1.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 3.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.6 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.2 0.9 GO:0046461 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.2 1.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 2.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 0.7 GO:0031053 primary miRNA processing(GO:0031053)
0.2 1.1 GO:0031282 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.2 0.5 GO:0015695 organic cation transport(GO:0015695)
0.2 2.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.2 0.9 GO:0042766 nucleosome mobilization(GO:0042766)
0.2 1.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 0.5 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 1.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.0 GO:0016559 peroxisome fission(GO:0016559)
0.2 3.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 4.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.0 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 5.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 1.3 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 0.9 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 6.1 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.2 1.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 3.4 GO:0051923 sulfation(GO:0051923)
0.2 0.6 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 2.7 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.2 0.6 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 3.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.9 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 1.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 5.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.9 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.1 0.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 2.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.6 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.1 2.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.2 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.4 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.1 4.6 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 3.1 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 2.6 GO:1990798 pancreas regeneration(GO:1990798)
0.1 7.3 GO:0007338 single fertilization(GO:0007338)
0.1 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.4 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 2.1 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 0.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 3.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.0 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.6 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 1.1 GO:0010884 positive regulation of lipid storage(GO:0010884) regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.1 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 2.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 3.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 3.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 1.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 1.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.9 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.3 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.8 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.8 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.1 2.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 2.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 2.1 GO:0044275 cellular carbohydrate catabolic process(GO:0044275)
0.1 0.5 GO:0035989 tendon development(GO:0035989)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.1 GO:0030810 activation of adenylate cyclase activity(GO:0007190) positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of cyclase activity(GO:0031281) positive regulation of adenylate cyclase activity(GO:0045762) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.4 GO:0046503 glycerophospholipid catabolic process(GO:0046475) glycerolipid catabolic process(GO:0046503)
0.1 1.1 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 1.1 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.1 0.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 2.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 7.3 GO:0031101 fin regeneration(GO:0031101)
0.1 3.7 GO:0007596 blood coagulation(GO:0007596)
0.1 1.3 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 1.3 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.0 GO:0010043 response to zinc ion(GO:0010043)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.7 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 0.4 GO:0035627 intracellular lipid transport(GO:0032365) ceramide transport(GO:0035627)
0.1 2.1 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 3.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 2.1 GO:0006284 base-excision repair(GO:0006284)
0.1 1.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 2.0 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 1.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 1.7 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.1 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 2.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 3.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 5.1 GO:0002250 adaptive immune response(GO:0002250)
0.1 3.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 3.6 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.1 2.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 2.2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.1 0.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.7 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.0 GO:0098659 inorganic cation import into cell(GO:0098659) inorganic ion import into cell(GO:0099587)
0.0 4.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984) trehalose metabolic process(GO:0005991)
0.0 5.4 GO:0034097 response to cytokine(GO:0034097)
0.0 1.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 1.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.9 GO:0008272 sulfate transport(GO:0008272)
0.0 0.7 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.9 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.8 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 1.3 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 2.0 GO:0060348 bone development(GO:0060348)
0.0 1.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 3.6 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.6 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0032616 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857) interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.4 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 2.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 2.3 GO:0006909 phagocytosis(GO:0006909)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.0 1.2 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0007548 sex differentiation(GO:0007548)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.6 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 3.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.2 GO:0001816 cytokine production(GO:0001816)
0.0 1.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 2.5 GO:0060326 cell chemotaxis(GO:0060326)
0.0 1.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.0 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 1.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.8 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 1.3 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.7 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.8 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.8 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 6.3 GO:0006955 immune response(GO:0006955)
0.0 0.8 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.8 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.1 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 4.6 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.3 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.2 GO:0009208 CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.0 0.7 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.1 GO:0014005 microglia development(GO:0014005)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 7.5 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.6 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052) positive regulation of cellular protein catabolic process(GO:1903364)
0.0 0.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.9 GO:0009611 response to wounding(GO:0009611)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0005577 fibrinogen complex(GO:0005577)
1.4 4.2 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
1.1 3.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.8 11.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 2.0 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.5 1.9 GO:0019815 B cell receptor complex(GO:0019815)
0.5 1.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.4 1.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 6.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 1.6 GO:0016600 flotillin complex(GO:0016600)
0.4 1.8 GO:0032433 filopodium tip(GO:0032433)
0.4 2.5 GO:0016234 inclusion body(GO:0016234)
0.3 1.0 GO:0034709 methylosome(GO:0034709)
0.3 1.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.3 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 5.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 5.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.9 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.2 0.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.2 0.8 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.7 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.5 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.2 2.4 GO:0002102 podosome(GO:0002102)
0.2 2.9 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.0 GO:0016589 NURF complex(GO:0016589)
0.2 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 3.3 GO:0005685 U1 snRNP(GO:0005685)
0.2 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 2.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 2.3 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0097268 cytoophidium(GO:0097268)
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 14.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.5 GO:0000145 exocyst(GO:0000145)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 0.9 GO:0034518 RNA cap binding complex(GO:0034518)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.1 GO:0030904 retromer complex(GO:0030904)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.3 GO:1990077 primosome complex(GO:1990077)
0.1 5.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.8 GO:0005795 Golgi stack(GO:0005795)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.3 GO:0089701 U2AF(GO:0089701)
0.1 10.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.7 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0015030 Cajal body(GO:0015030)
0.1 2.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 3.5 GO:0005604 basement membrane(GO:0005604)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 3.6 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.1 0.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 15.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 65.9 GO:0005615 extracellular space(GO:0005615)
0.1 3.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.8 GO:0005811 lipid particle(GO:0005811)
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.1 GO:0008278 cohesin complex(GO:0008278)
0.0 1.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 26.1 GO:0005576 extracellular region(GO:0005576)
0.0 2.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 4.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 1.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 5.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 24.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.8 GO:0031984 trans-Golgi network(GO:0005802) organelle subcompartment(GO:0031984) Golgi subcompartment(GO:0098791)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 5.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.5 GO:0016604 nuclear body(GO:0016604)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
1.7 5.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.6 4.7 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
1.6 4.7 GO:0005499 vitamin D binding(GO:0005499)
1.4 5.6 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.4 4.2 GO:0033897 ribonuclease T2 activity(GO:0033897)
1.3 7.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.3 3.9 GO:0034185 apolipoprotein binding(GO:0034185)
1.1 8.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 4.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
1.1 4.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 5.9 GO:0070330 aromatase activity(GO:0070330)
0.9 3.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.8 3.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.8 3.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.8 5.3 GO:0034632 retinol transporter activity(GO:0034632)
0.7 5.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 2.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.7 2.9 GO:0008169 C-methyltransferase activity(GO:0008169)
0.7 2.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.7 4.9 GO:0019809 spermidine binding(GO:0019809)
0.7 2.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.7 4.7 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.6 12.8 GO:0003785 actin monomer binding(GO:0003785)
0.6 3.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.6 1.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 1.8 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.6 1.7 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.6 17.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.6 2.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.6 1.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.6 1.7 GO:0098808 mRNA cap binding(GO:0098808)
0.5 2.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.5 4.9 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.5 2.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.5 4.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.5 3.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.5 3.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.5 1.5 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.5 3.3 GO:0015250 water channel activity(GO:0015250)
0.5 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.5 4.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 2.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 3.5 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.4 1.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 1.3 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.4 1.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.4 1.2 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.4 9.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 1.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 1.9 GO:0050699 WW domain binding(GO:0050699)
0.4 1.5 GO:0005521 lamin binding(GO:0005521)
0.4 3.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 5.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 1.3 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.3 1.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.3 4.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 9.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 2.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 2.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.9 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.3 1.4 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 1.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.3 0.8 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.3 2.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 2.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.0 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 14.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 6.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.2 1.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 1.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 4.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 2.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 1.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 2.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.9 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 5.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.2 10.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 1.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 2.1 GO:0008199 ferric iron binding(GO:0008199)
0.2 3.8 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 0.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.8 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 6.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.8 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 0.7 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.2 2.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 2.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.4 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.2 2.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 2.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 1.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 7.6 GO:0009055 electron carrier activity(GO:0009055)
0.1 0.9 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.3 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 4.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 4.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.4 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 2.4 GO:0030552 cAMP binding(GO:0030552)
0.1 3.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 3.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 5.9 GO:0008009 chemokine activity(GO:0008009)
0.1 4.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 7.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.0 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 3.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.3 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.3 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 8.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 3.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 4.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 5.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 2.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.3 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 9.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 4.4 GO:0003823 antigen binding(GO:0003823)
0.1 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 33.8 GO:0046983 protein dimerization activity(GO:0046983)
0.1 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 5.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 8.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.9 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.1 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.5 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 4.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 1.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 3.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.0 2.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 3.5 GO:0046906 tetrapyrrole binding(GO:0046906)
0.0 9.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 2.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 5.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 4.7 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 3.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0050780 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 1.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 14.4 GO:0008289 lipid binding(GO:0008289)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 1.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.1 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 4.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0051287 NAD binding(GO:0051287)
0.0 1.2 GO:0016829 lyase activity(GO:0016829)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.5 21.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 7.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 2.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 3.2 PID ALK2 PATHWAY ALK2 signaling events
0.2 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.0 PID CONE PATHWAY Visual signal transduction: Cones
0.2 4.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 2.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.5 PID ARF 3PATHWAY Arf1 pathway
0.1 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.4 PID BMP PATHWAY BMP receptor signaling
0.1 1.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.7 5.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 6.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 12.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.5 6.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 6.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.5 2.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 5.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.4 3.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 0.8 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.4 3.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 3.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 7.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 1.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 3.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 1.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 7.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 1.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 1.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 6.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 2.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 3.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 3.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 5.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 3.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.9 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.4 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation