Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Z-value: 1.30

Motif logo

Transcription factors associated with meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Gene Symbol Gene ID Gene Info
ENSDARG00000077840 Meis homeobox 2a
ENSDARG00000098240 Meis homeobox 2a
ENSDARG00000112895 homeobox protein TGIF2-like
ENSDARG00000018765 pbx/knotted 1 homeobox 1.1
ENSDARG00000036542 pbx/knotted 1 homeobox 1.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pknox1.2dr11_v1_chr1_-_46981134_469811340.348.8e-04Click!
meis2bdr11_v1_chr20_-_10118818_10118818-0.285.9e-03Click!
pknox1.1dr11_v1_chr9_+_19529951_195299510.223.4e-02Click!
FO834857.1dr11_v1_chr6_-_1820606_18206060.075.3e-01Click!
meis2adr11_v1_chr17_+_52823015_52823138-0.065.5e-01Click!

Activity profile of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Sorted Z-values of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_58332000 17.04 ENSDART00000145234
gamma-glutamyltransferase 1 like 2.1
chr3_-_36612877 13.88 ENSDART00000167164
si:dkeyp-72e1.7
chr7_+_14291323 11.82 ENSDART00000053521
Rh family, C glycoprotein a
chr21_-_38153824 11.27 ENSDART00000151226
Kruppel-like factor 5 like
chr19_-_5369486 10.64 ENSDART00000105004
keratin 17
chr5_-_12587053 8.77 ENSDART00000162780
V-set and immunoglobulin domain containing 10
chr19_+_7567763 8.70 ENSDART00000140411
S100 calcium binding protein A11
chr8_+_34731982 8.60 ENSDART00000066050
4-hydroxyphenylpyruvate dioxygenase b
chr21_+_45627775 8.58 ENSDART00000185466
interferon regulatory factor 1b
chr7_+_51103416 8.37 ENSDART00000174236
collagen, type IV, alpha 5 (Alport syndrome)
chr4_+_7841627 7.86 ENSDART00000037997
upper zone of growth plate and cartilage matrix associated a
chr22_+_19188809 7.42 ENSDART00000134791
ENSDART00000133682
si:dkey-21e2.8
chr20_-_27733683 7.28 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr9_-_48281941 7.05 ENSDART00000099787
kelch-like family member 41a
chr15_+_27364394 6.89 ENSDART00000122101
T-box 2b
chr5_+_72145468 6.81 ENSDART00000148626
c-abl oncogene 1, non-receptor tyrosine kinase
chr12_-_48168135 6.54 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr4_+_73085993 6.50 ENSDART00000165749
si:ch73-170d6.2
chr9_-_31135901 6.48 ENSDART00000113027
ENSDART00000193210
ENSDART00000128896
si:ch211-184m13.4
chr1_-_8653385 6.26 ENSDART00000193041
actin, beta 1
chr24_+_10413484 6.25 ENSDART00000111014
MYC proto-oncogene, bHLH transcription factor a
chr24_-_40667800 6.08 ENSDART00000169315
slow myosin heavy chain 1
chr17_-_23673864 6.06 ENSDART00000104738
ENSDART00000128958
phosphatase and tensin homolog A
chr4_+_22613625 6.02 ENSDART00000131161
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_23397785 6.01 ENSDART00000148961
S100 calcium binding protein A10b
chr1_-_19402802 5.90 ENSDART00000135552
RNA binding motif protein 47
chr2_-_11027258 5.85 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
single stranded DNA binding protein 3a
chr22_-_6194517 5.81 ENSDART00000134757
ENSDART00000181598
ENSDART00000129829
si:rp71-36a1.5
chr5_+_30741730 5.79 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr12_-_44307963 5.78 ENSDART00000161009
si:ch73-329n5.1
chr23_-_9768700 5.53 ENSDART00000045126
laminin, alpha 5
chr20_+_29634653 5.51 ENSDART00000101556
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2b
chr10_+_35417099 5.50 ENSDART00000063398
HERV-H LTR-associating 2a, tandem duplicate 1
chr5_-_323712 5.40 ENSDART00000188793
hook microtubule tethering protein 3
chr8_-_32385989 5.31 ENSDART00000143716
ENSDART00000098850
lipase, endothelial
chr14_+_22022441 5.27 ENSDART00000149121
cardiotrophin-like cytokine factor 1
chr5_+_22307605 5.25 ENSDART00000138154
Rho GTPase activating protein 20b
chr6_+_23931236 5.19 ENSDART00000166079
growth arrest and DNA-damage-inducible, alpha, b
chr16_+_23398369 5.15 ENSDART00000037694
S100 calcium binding protein A10b
chr24_+_42148140 5.13 ENSDART00000010658
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr12_-_43982343 5.10 ENSDART00000161539

chr6_+_49052741 5.03 ENSDART00000011876
synaptonemal complex protein 1
chr13_-_42749916 4.87 ENSDART00000140019
calpain 2, (m/II) large subunit a
chr18_+_29402623 4.85 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr19_-_38611814 4.85 ENSDART00000151958
collagen, type XVI, alpha 1
chr11_-_39202915 4.84 ENSDART00000105133
wingless-type MMTV integration site family, member 4a
chr1_-_58000438 4.63 ENSDART00000163761
si:ch211-114l13.9
chr22_-_17677947 4.43 ENSDART00000139911
tight junction protein 3
chr12_+_18358082 4.42 ENSDART00000123315
si:dkey-7e14.3
chr17_-_24890843 4.35 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
UDP-galactose-4-epimerase
chr21_-_27338639 4.30 ENSDART00000130632
hypoxia-inducible factor 1, alpha subunit, like 2
chr3_-_50147160 4.28 ENSDART00000191341
bloodthirsty-related gene family, member 2
chr1_+_57187794 4.28 ENSDART00000152485
si:dkey-27j5.9
chr15_-_19724932 4.25 ENSDART00000152345
synaptotagmin-like 2b
chr7_+_6879534 4.24 ENSDART00000157731
zgc:175248
chr1_+_14253118 4.16 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr13_+_45524475 4.13 ENSDART00000074567
ENSDART00000019113
macoilin 1b
chr7_+_17816006 4.12 ENSDART00000080834
echinoderm microtubule associated protein like 3
chr15_-_28587147 4.11 ENSDART00000156049
slingshot protein phosphatase 2a
chr23_-_19103855 4.11 ENSDART00000016901
par-6 partitioning defective 6 homolog beta (C. elegans)
chr1_+_58150000 4.06 ENSDART00000137836
si:ch211-15j1.3
chr5_-_56513825 4.05 ENSDART00000024207
T-box 2a
chr17_-_7792376 4.04 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr18_+_44673990 4.04 ENSDART00000018625
N-ethylmaleimide-sensitive factor attachment protein, alpha b
chr3_+_22273123 4.03 ENSDART00000044157
sodium channel, voltage-gated, type IV, alpha, b
chr18_+_29403017 4.02 ENSDART00000176966
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr4_+_12931763 4.00 ENSDART00000016382
wnt inhibitory factor 1
chr16_+_33144306 3.98 ENSDART00000101953
rhomboid, veinlet-like 2 (Drosophila)
chr4_-_685412 3.96 ENSDART00000168167
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr8_+_25616946 3.96 ENSDART00000133983
solute carrier family 38, member 5a
chr13_+_46803979 3.92 ENSDART00000159260

chr13_+_18321140 3.91 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr1_+_2301961 3.89 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_27364338 3.88 ENSDART00000186759
fibulin 2
chr8_+_23639124 3.87 ENSDART00000083108
5'-nucleotidase domain containing 2
chr3_-_1400309 3.86 ENSDART00000159893
WW domain binding protein 11
chr21_-_41025340 3.81 ENSDART00000148231
PLAC8-like 1
chr13_+_30696286 3.80 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr14_-_34605607 3.74 ENSDART00000191608
actin filament associated protein 1-like 1a
chr20_+_32152355 3.69 ENSDART00000152904
ENSDART00000139507
sestrin 1
chr13_-_7031033 3.68 ENSDART00000193211

chr14_+_35369979 3.67 ENSDART00000144702
ENSDART00000169712
clathrin interactor 1a
chr12_-_46176115 3.62 ENSDART00000152848
si:ch211-226h7.8
chr12_-_36511939 3.61 ENSDART00000153759
unc-13 homolog D (C. elegans)
chr12_-_43693192 3.60 ENSDART00000172284

chr6_-_10809546 3.60 ENSDART00000151661
WAS/WASL interacting protein family, member 1b
chr16_-_52646789 3.59 ENSDART00000035761
ubiquitin protein ligase E3 component n-recognin 5
chr20_+_21391181 3.58 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jagged 2b
chr23_+_20408227 3.52 ENSDART00000134727
si:rp71-17i16.4
chr7_+_17816470 3.51 ENSDART00000173807
echinoderm microtubule associated protein like 3
chr3_+_17030665 3.48 ENSDART00000159849
ENSDART00000174491
ENSDART00000104519
ENSDART00000080854
signal transducer and activator of transcription 3 (acute-phase response factor)
chr5_-_71722257 3.45 ENSDART00000013404
adenylate kinase 1
chr9_+_27876146 3.45 ENSDART00000133997
armadillo repeat containing 8
chr1_+_1805294 3.41 ENSDART00000103850
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr1_-_30473422 3.39 ENSDART00000164202
insulin-like growth factor 2 mRNA binding protein 2b
chr1_-_10821584 3.36 ENSDART00000167452
ENSDART00000162137
cytokine receptor family member B15
chr16_+_1383914 3.35 ENSDART00000185089
ceramide synthase 2b
chr6_+_46320693 3.31 ENSDART00000128621
ENSDART00000155917
si:dkeyp-67f1.2
chr2_+_394166 3.28 ENSDART00000155733
myosin light chain kinase family, member 4a
chr16_+_33144112 3.25 ENSDART00000183149
rhomboid, veinlet-like 2 (Drosophila)
chr12_+_33320884 3.14 ENSDART00000188988
casein kinase 1, delta b
chr5_-_37103487 3.14 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr3_-_55099272 3.12 ENSDART00000130869
hemoglobin, beta adult 1
chr14_+_29769336 3.12 ENSDART00000105898
si:dkey-34l15.1
chr7_+_65673885 3.07 ENSDART00000169182
parvin, alpha b
chr20_-_54564018 3.06 ENSDART00000099832
zgc:153012
chr3_-_55104310 3.05 ENSDART00000101713
hemoglobin, beta adult 1
chr11_+_27274355 3.03 ENSDART00000113707
fibulin 2
chr4_+_76775837 3.03 ENSDART00000174167
membrane-spanning 4-domains, subfamily A, member 17A.10
chr13_+_35765317 3.01 ENSDART00000100156
ENSDART00000167650
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr2_+_55365727 2.99 ENSDART00000162943

chr23_-_20309505 2.98 ENSDART00000130856
laminin, beta 2-like
chr5_-_41124241 2.97 ENSDART00000083561
myotubularin related protein 12
chr1_-_11075403 2.91 ENSDART00000102903
ENSDART00000170290
dystrophin
chr18_-_6943577 2.91 ENSDART00000132399
si:dkey-266m15.6
chr11_+_45436703 2.91 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr15_-_14212777 2.90 ENSDART00000165572

chr19_+_7575141 2.88 ENSDART00000051528
S100 calcium binding protein U
chr11_+_27364059 2.85 ENSDART00000172883
fibulin 2
chr19_-_35035857 2.84 ENSDART00000103253
bone morphogenetic protein 8a
chr7_+_17816623 2.83 ENSDART00000173963
echinoderm microtubule associated protein like 3
chr15_-_28587490 2.83 ENSDART00000186196
slingshot protein phosphatase 2a
chr3_+_17616201 2.82 ENSDART00000156775
RAB5C, member RAS oncogene family
chr8_+_7033049 2.74 ENSDART00000064172
ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr5_-_35200590 2.73 ENSDART00000051271
FCH domain only 2
chr10_-_8294965 2.72 ENSDART00000167380
phospholipid phosphatase 1a
chr15_+_36445350 2.71 ENSDART00000154552
si:dkey-262k9.2
chr19_-_6134802 2.71 ENSDART00000140051
capicua transcriptional repressor a
chr11_+_25459697 2.70 ENSDART00000161481
opsin 1 (cone pigments), short-wave-sensitive 2
chr18_+_35128685 2.69 ENSDART00000151579
si:ch211-195m9.3
chr15_-_35252522 2.65 ENSDART00000144153
ENSDART00000059195
mitochondrial fission factor
chr4_+_76692834 2.65 ENSDART00000064315
ENSDART00000137653
membrane-spanning 4-domains, subfamily A, member 17A.1
chr9_-_52490579 2.62 ENSDART00000161667
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr5_+_44346691 2.61 ENSDART00000034523
threonyl-tRNA synthetase
chr5_-_24127310 2.61 ENSDART00000182700
ENSDART00000154313
capping protein (actin filament), gelsolin-like a
chr9_+_33267211 2.53 ENSDART00000025635
ubiquitin specific peptidase 9
chr20_-_20270191 2.52 ENSDART00000009356
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr5_-_39805620 2.51 ENSDART00000137801
RasGEF domain family, member 1Ba
chr19_+_7575341 2.50 ENSDART00000134271
S100 calcium binding protein U
chr23_-_38054 2.49 ENSDART00000170393

chr11_-_29916607 2.48 ENSDART00000138912
ENSDART00000079152
vascular endothelial growth factor D
chr20_+_1329509 2.47 ENSDART00000017791
ENSDART00000136669
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr9_-_22821901 2.47 ENSDART00000101711
nebulin
chr13_-_7233811 2.40 ENSDART00000162026
ninein-like
chr9_-_7539297 2.40 ENSDART00000081550
ENSDART00000081553
desmin a
chr5_-_37900350 2.36 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr23_-_36592436 2.36 ENSDART00000168246
SPRY domain containing 3
chr14_+_48862987 2.35 ENSDART00000167810
zgc:154054
chr7_+_34794829 2.35 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr7_-_71331690 2.30 ENSDART00000149682
DEAH (Asp-Glu-Ala-His) box helicase 15
chr13_-_12581388 2.28 ENSDART00000079655
glutamyl aminopeptidase
chr19_+_19772765 2.27 ENSDART00000182028
ENSDART00000161019
homeobox A3a
chr14_-_25956804 2.27 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_+_26667475 2.26 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr10_-_8295294 2.26 ENSDART00000075412
ENSDART00000163803
phospholipid phosphatase 1a
chr13_-_15700060 2.20 ENSDART00000170689
ENSDART00000010986
ENSDART00000101741
ENSDART00000139124
creatine kinase, brain a
chr6_-_49510553 2.19 ENSDART00000166238
ribosomal protein, large P2
chr6_+_58915889 2.19 ENSDART00000083628
DNA-damage-inducible transcript 3
chr18_+_24562188 2.15 ENSDART00000099463
LysM, putative peptidoglycan-binding, domain containing 4
chr25_-_21822426 2.12 ENSDART00000151993
zgc:158222
chr14_-_34605804 2.09 ENSDART00000144547
actin filament associated protein 1-like 1a
chr8_+_23709280 2.07 ENSDART00000185842
peroxisome proliferator-activated receptor delta b
chr11_+_5880562 2.07 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
DAZ associated protein 1
chr25_+_5068442 2.03 ENSDART00000097522
parvin, gamma
chr20_+_26690036 2.02 ENSDART00000103232
forkhead box F2b
chr12_-_18898413 2.01 ENSDART00000181281
ENSDART00000121866
desumoylating isopeptidase 1b
chr10_+_20590190 2.01 ENSDART00000131819
leucine zipper-EF-hand containing transmembrane protein 2
chr2_+_36103309 1.99 ENSDART00000190038

chr5_+_27432958 1.98 ENSDART00000124705
histone H1 like
chr2_+_3696038 1.97 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr1_+_41478345 1.95 ENSDART00000134626
docking protein 1a
chr6_-_42003780 1.95 ENSDART00000032527
caveolin 3
chr7_-_71331499 1.94 ENSDART00000081245
DEAH (Asp-Glu-Ala-His) box helicase 15
chr19_-_12212692 1.93 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
zinc finger protein 706
chr23_+_6586467 1.92 ENSDART00000081763
ENSDART00000121480
RNA binding motif protein 38
chr23_-_20258490 1.91 ENSDART00000147326
laminin, beta 2 (laminin S)
chr1_+_54865552 1.88 ENSDART00000145381
si:ch211-196h16.5
chr3_+_29941777 1.88 ENSDART00000113889
interferon-induced protein 35
chr7_-_56766100 1.88 ENSDART00000189934
casein kinase 2, alpha prime polypeptide a
chr21_+_45758498 1.85 ENSDART00000162548
H2A histone family, member Y
chr2_-_45510699 1.85 ENSDART00000024034
ENSDART00000145634
G protein signaling modulator 2
chr3_-_50146854 1.84 ENSDART00000157047
si:dkey-120c6.5
chr22_-_37834312 1.84 ENSDART00000076128
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr3_+_53317040 1.84 ENSDART00000011780
XPA binding protein 2
chr7_+_21768452 1.83 ENSDART00000127719
lysine (K)-specific demethylase 6B, a
chr3_+_13190012 1.82 ENSDART00000179747
ENSDART00000109876
ENSDART00000124824
ENSDART00000130261
Sad1 and UNC84 domain containing 1
chr19_-_81477 1.80 ENSDART00000159815
heterogeneous nuclear ribonucleoprotein R
chr22_-_17458070 1.79 ENSDART00000139658
si:ch211-197g15.10
chr1_-_52437056 1.78 ENSDART00000138337
si:ch211-217k17.12
chr3_+_24275766 1.74 ENSDART00000055607
platelet-derived growth factor beta polypeptide b
chr19_-_2861444 1.74 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr9_-_22822084 1.67 ENSDART00000142020
nebulin
chr20_+_27712714 1.67 ENSDART00000008306
zinc finger and BTB domain containing 1
chr5_-_23795688 1.65 ENSDART00000099084
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr12_-_48467733 1.64 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
SEC31 homolog B, COPII coat complex component
chr23_-_23401305 1.62 ENSDART00000078936
hairy-related 9
chr8_-_17184482 1.62 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr16_+_5251768 1.61 ENSDART00000144558
plectin b
chr11_+_6136220 1.61 ENSDART00000082223
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr11_+_44356504 1.60 ENSDART00000160678
serine/arginine-rich splicing factor 7b

Network of associatons between targets according to the STRING database.

First level regulatory network of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
2.2 17.9 GO:0031179 peptide modification(GO:0031179)
1.7 5.0 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
1.7 8.4 GO:0007412 axon target recognition(GO:0007412)
1.5 11.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.5 5.9 GO:0016554 cytidine to uridine editing(GO:0016554)
1.4 4.2 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
1.2 6.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
1.2 3.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
1.1 3.3 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
1.0 4.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.0 4.0 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
1.0 6.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.9 4.3 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.8 4.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.8 5.3 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.7 8.6 GO:0050688 regulation of defense response to virus(GO:0050688)
0.7 4.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.7 2.7 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.7 2.0 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.6 2.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.6 3.6 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.6 5.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 2.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.5 1.6 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.5 3.7 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.5 7.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.5 3.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 5.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.5 3.4 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.5 2.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 4.4 GO:0030104 water homeostasis(GO:0030104)
0.4 1.8 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.4 1.3 GO:0003156 regulation of organ formation(GO:0003156)
0.4 7.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.4 2.0 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.4 1.2 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.4 4.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.4 1.6 GO:0046324 regulation of glucose import(GO:0046324)
0.4 2.6 GO:0048478 embryonic body morphogenesis(GO:0010172) replication fork protection(GO:0048478)
0.4 3.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.3 1.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.3 1.3 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.3 2.3 GO:0060017 parathyroid gland development(GO:0060017)
0.3 1.0 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.3 1.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3 1.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 1.2 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.3 1.2 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.3 6.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 3.2 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.1 GO:0019532 oxalate transport(GO:0019532)
0.3 1.0 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.3 3.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.3 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 0.8 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 2.5 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 5.2 GO:0015671 oxygen transport(GO:0015671)
0.2 1.9 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) muscle cell cellular homeostasis(GO:0046716) caveola assembly(GO:0070836)
0.2 5.5 GO:0035141 medial fin morphogenesis(GO:0035141)
0.2 4.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 3.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.3 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.2 1.4 GO:0048069 eye pigmentation(GO:0048069)
0.2 1.6 GO:0042026 protein refolding(GO:0042026)
0.2 2.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.6 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 5.3 GO:0070831 basement membrane assembly(GO:0070831)
0.2 3.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 1.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 2.5 GO:0045682 regulation of epidermis development(GO:0045682)
0.2 4.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.2 0.8 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.2 2.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 0.8 GO:0060036 notochord cell vacuolation(GO:0060036)
0.2 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.2 0.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) mitochondrial respiratory chain complex III assembly(GO:0034551) protein insertion into mitochondrial membrane(GO:0051204) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.7 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.2 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 15.6 GO:0031101 fin regeneration(GO:0031101)
0.1 0.4 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 1.4 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 3.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 2.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.6 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.5 GO:0006297 leading strand elongation(GO:0006272) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 2.0 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 9.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 5.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 6.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.1 4.0 GO:0048794 swim bladder development(GO:0048794)
0.1 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 10.1 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 2.3 GO:0043171 peptide catabolic process(GO:0043171)
0.1 3.9 GO:0003094 glomerular filtration(GO:0003094)
0.1 1.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.5 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.7 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 1.8 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 0.7 GO:0071711 basement membrane organization(GO:0071711)
0.1 0.7 GO:0032475 otolith formation(GO:0032475)
0.1 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 4.5 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.0 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.1 GO:0032418 lysosome localization(GO:0032418)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 4.1 GO:0006405 RNA export from nucleus(GO:0006405)
0.1 1.4 GO:0048278 vesicle docking(GO:0048278)
0.1 3.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 1.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 17.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.4 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 5.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.3 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.1 1.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.7 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 7.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.2 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 2.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 4.7 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 5.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 6.0 GO:1990266 neutrophil migration(GO:1990266)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.1 2.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.3 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 3.8 GO:0007098 centrosome cycle(GO:0007098)
0.1 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 3.1 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.9 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 1.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.6 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 1.0 GO:0001757 somite specification(GO:0001757)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 2.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.7 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 1.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.5 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 4.1 GO:0006413 translational initiation(GO:0006413)
0.0 4.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 2.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.3 GO:0030282 bone mineralization(GO:0030282)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 9.1 GO:0006887 exocytosis(GO:0006887)
0.0 1.7 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 1.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.1 GO:0006400 tRNA modification(GO:0006400)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.3 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.2 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 6.5 GO:0001525 angiogenesis(GO:0001525)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 7.1 GO:0006955 immune response(GO:0006955)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:0034694 response to prostaglandin(GO:0034694) cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.8 GO:0032869 response to insulin(GO:0032868) cellular response to insulin stimulus(GO:0032869)
0.0 0.3 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.6 GO:0016485 protein processing(GO:0016485)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0030162 regulation of proteolysis(GO:0030162)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0043073 germ cell nucleus(GO:0043073)
1.3 6.3 GO:0097433 dense body(GO:0097433)
1.0 4.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.7 3.4 GO:0034657 GID complex(GO:0034657)
0.6 4.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 10.8 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.5 3.7 GO:0061700 GATOR2 complex(GO:0061700)
0.5 2.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 6.2 GO:0005833 hemoglobin complex(GO:0005833)
0.4 5.8 GO:0002102 podosome(GO:0002102)
0.4 1.2 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 2.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 1.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 1.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 1.2 GO:1990909 Wnt signalosome(GO:1990909)
0.3 1.4 GO:0000814 ESCRT II complex(GO:0000814)
0.3 7.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.8 GO:0000974 Prp19 complex(GO:0000974)
0.2 3.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 4.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 4.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 2.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 6.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 6.1 GO:0016605 PML body(GO:0016605)
0.2 3.1 GO:0005876 spindle microtubule(GO:0005876)
0.2 16.2 GO:0005882 intermediate filament(GO:0005882)
0.1 3.6 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 3.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.9 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 8.4 GO:0005604 basement membrane(GO:0005604)
0.1 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 1.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.4 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 2.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 4.3 GO:0005861 troponin complex(GO:0005861)
0.1 1.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 4.2 GO:0005643 nuclear pore(GO:0005643)
0.1 5.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 7.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 10.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 6.9 GO:0016459 myosin complex(GO:0016459)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.4 GO:0031082 BLOC complex(GO:0031082)
0.1 1.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 5.0 GO:0005884 actin filament(GO:0005884)
0.1 8.3 GO:0005681 spliceosomal complex(GO:0005681)
0.1 5.1 GO:0005925 focal adhesion(GO:0005925)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 12.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 55.5 GO:0005615 extracellular space(GO:0005615)
0.0 2.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 3.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 3.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.0 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 11.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 11.9 GO:0005576 extracellular region(GO:0005576)
0.0 1.4 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0030141 secretory granule(GO:0030141)
0.0 8.6 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0001726 ruffle(GO:0001726)
0.0 4.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.7 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
2.0 17.9 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
1.7 5.0 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
1.5 6.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
1.4 4.3 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
1.3 6.3 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.0 4.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
1.0 28.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.9 2.6 GO:0036310 annealing helicase activity(GO:0036310)
0.8 2.5 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.8 4.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.7 2.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.7 4.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.7 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 3.7 GO:0070728 leucine binding(GO:0070728)
0.5 1.9 GO:0071253 connexin binding(GO:0071253)
0.5 5.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.5 11.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 2.1 GO:0034046 poly(G) binding(GO:0034046)
0.4 6.0 GO:0038191 neuropilin binding(GO:0038191)
0.4 1.5 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 3.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 4.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 2.8 GO:0070700 BMP receptor binding(GO:0070700)
0.3 4.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 7.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 3.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 5.2 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.2 11.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.2 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.2 1.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 4.1 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 3.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 3.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 24.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 2.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 1.0 GO:0070330 aromatase activity(GO:0070330)
0.2 2.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 4.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 4.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 4.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.1 3.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.6 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 9.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 3.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.6 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.7 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 2.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 5.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0008430 selenium binding(GO:0008430)
0.1 7.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.1 15.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.8 GO:0008009 chemokine activity(GO:0008009)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.3 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.1 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 2.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.0 GO:0031386 protein tag(GO:0031386)
0.1 3.0 GO:0043022 ribosome binding(GO:0043022)
0.1 2.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 6.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 4.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 2.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 2.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 4.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 3.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.7 GO:0008201 heparin binding(GO:0008201)
0.0 4.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 21.0 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 4.2 GO:0000149 SNARE binding(GO:0000149)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 6.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 9.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 4.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 2.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 7.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 3.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 3.5 ST STAT3 PATHWAY STAT3 Pathway
0.3 13.2 NABA COLLAGENS Genes encoding collagen proteins
0.3 6.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 4.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 4.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 11.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 5.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 17.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 13.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.0 PID AURORA A PATHWAY Aurora A signaling
0.1 1.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 1.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 4.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 4.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 3.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 14.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 7.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 1.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 2.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 0.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 6.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 3.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 5.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 3.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 7.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 4.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.7 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.6 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression