Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for mef2ca+mef2cb

Z-value: 2.80

Motif logo

Transcription factors associated with mef2ca+mef2cb

Gene Symbol Gene ID Gene Info
ENSDARG00000009418 myocyte enhancer factor 2cb
ENSDARG00000029764 myocyte enhancer factor 2ca

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2cadr11_v1_chr10_-_43568239_435682410.809.8e-22Click!
mef2cbdr11_v1_chr5_-_48307804_483078040.557.9e-09Click!

Activity profile of mef2ca+mef2cb motif

Sorted Z-values of mef2ca+mef2cb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_11201096 74.60 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr3_-_61205711 57.34 ENSDART00000055062
parvalbumin 1
chr5_+_51597677 53.31 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr12_-_26064480 51.06 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
LIM domain binding 3b
chr25_+_29160102 49.82 ENSDART00000162854
pyruvate kinase M1/2b
chr12_-_26064105 49.54 ENSDART00000168825
LIM domain binding 3b
chr11_+_11200550 48.48 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr11_-_18253111 47.62 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr15_-_23645810 44.37 ENSDART00000168845
creatine kinase, muscle b
chr9_-_42873700 42.94 ENSDART00000125953
titin, tandem duplicate 1
chr12_+_18524953 41.74 ENSDART00000090332
neuralized E3 ubiquitin protein ligase 2
chr12_-_17707449 41.22 ENSDART00000142427
ENSDART00000034914
parvalbumin 3
chr17_-_5583345 38.86 ENSDART00000035944
chloride intracellular channel 5a
chr13_+_22249636 38.57 ENSDART00000108472
ENSDART00000173123
synaptopodin 2-like a
chr2_+_30916188 37.92 ENSDART00000137012
myomesin 1a (skelemin)
chr5_-_72125551 36.32 ENSDART00000149412
SET and MYND domain containing 1a
chr12_+_6002715 34.90 ENSDART00000114961
si:ch211-131k2.3
chr6_+_29410986 34.38 ENSDART00000065293
ubiquitin specific peptidase 13
chr16_+_29663809 34.38 ENSDART00000191336
tropomodulin 4 (muscle)
chr16_-_17200120 33.97 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr8_-_26388090 33.52 ENSDART00000147912
si:dkey-20d21.12
chr1_+_7546259 33.36 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr6_-_18199062 33.35 ENSDART00000167513
protein phosphatase 1, regulatory subunit 27b
chr25_-_31396479 33.27 ENSDART00000156828
proline rich 33
chr8_-_18535822 31.72 ENSDART00000100558
nexilin (F actin binding protein)
chr12_-_26430507 31.33 ENSDART00000153214
synaptopodin 2-like b
chr13_+_22480857 31.14 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr6_+_3680651 29.05 ENSDART00000013588
kelch-like family member 41b
chr9_-_6927587 28.55 ENSDART00000059092
transmembrane protein 182a
chr7_-_71758613 28.32 ENSDART00000166724
myomesin 1b
chr16_+_25245857 27.87 ENSDART00000155220
kelch-like family member 38b
chr4_+_6572364 27.81 ENSDART00000122574
protein phosphatase 1, regulatory subunit 3Aa
chr21_-_22730832 27.61 ENSDART00000101797
F-box protein 40, tandem duplicate 1
chr9_-_14108896 26.69 ENSDART00000135209
protein kinase, AMP-activated, gamma 3b non-catalytic subunit
chr24_+_34089977 26.66 ENSDART00000157466
ankyrin repeat and SOCS box containing 10
chr9_-_43142636 26.50 ENSDART00000134349
ENSDART00000181835
coiled-coil domain containing 141
chr24_+_34085940 26.05 ENSDART00000171189
ankyrin repeat and SOCS box containing 10
chr9_-_33107237 25.89 ENSDART00000013918
calsequestrin 2
chr14_-_12307522 25.49 ENSDART00000163900
myotilin
chr23_-_5685023 25.02 ENSDART00000148680
ENSDART00000149365
troponin T type 2a (cardiac)
chr13_-_2189761 24.95 ENSDART00000166255
muscular LMNA-interacting protein
chr2_-_23768818 24.83 ENSDART00000148685
ENSDART00000191167
xin actin binding repeat containing 1
chr25_-_26736088 24.79 ENSDART00000067114
F-box and leucine-rich repeat protein 22
chr23_-_21515182 24.64 ENSDART00000142000
ring finger protein 207b
chr23_+_18722715 24.60 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr7_-_23745984 23.98 ENSDART00000048050
zgc:92429
chr4_-_9592402 23.10 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr9_-_34191627 22.50 ENSDART00000142664
ddb1 and cul4 associated factor 6
chr24_-_40700596 22.44 ENSDART00000162635
slow myosin heavy chain 2
chr5_+_64368770 21.98 ENSDART00000162246
phospholipid phosphatase 7 (inactive)
chr20_-_9980318 21.66 ENSDART00000080664
zgc:86709
chr22_+_16308450 20.96 ENSDART00000105678
leucine rich repeat containing 39
chr3_+_28953274 20.73 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr23_+_24931999 20.72 ENSDART00000136162
ENSDART00000140335
kelch-like family member 21
chr6_+_14301214 20.50 ENSDART00000129491
transmembrane protein 182b
chr4_-_4119396 20.47 ENSDART00000067409
ENSDART00000138221
leiomodin 2 (cardiac) b
chr22_+_16308806 20.20 ENSDART00000162685
leucine rich repeat containing 39
chr19_-_9662958 20.03 ENSDART00000041094
chloride channel, voltage-sensitive 1a
chr24_+_25471196 19.74 ENSDART00000066625
small muscle protein, X-linked
chr1_-_38813679 19.46 ENSDART00000148917
ankyrin repeat and SOCS box containing 5b
chr21_-_22737228 19.11 ENSDART00000151366
F-box protein 40, tandem duplicate 2
chr23_+_18722915 18.91 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr12_+_3078221 18.70 ENSDART00000148835
ENSDART00000149427
sarcoglycan, alpha
chr11_-_25213651 18.62 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr9_-_23894392 18.43 ENSDART00000133417
ankyrin repeat and SOCS box containing 18
chr8_-_17980317 18.42 ENSDART00000129148
TNNI3 interacting kinase
chr9_-_23891102 18.31 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr23_+_17417539 18.01 ENSDART00000182605

chr16_-_43356018 17.71 ENSDART00000181683

chr11_-_43104475 17.55 ENSDART00000125368
acylphosphatase 2, muscle type
chr8_-_11229523 17.53 ENSDART00000002164
unc-45 myosin chaperone B
chr25_+_20089986 16.77 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr24_+_9298198 16.56 ENSDART00000165780
OTU deubiquitinase 1
chr22_+_396840 15.88 ENSDART00000163198
capping protein (actin filament) muscle Z-line, beta
chr3_+_59851537 15.72 ENSDART00000180997

chr4_-_2350371 15.63 ENSDART00000166274
pleckstrin homology-like domain, family A, member 1
chr7_-_71758307 15.60 ENSDART00000161067
ENSDART00000165253
myomesin 1b
chr2_-_6182098 15.52 ENSDART00000156167
si:ch73-182a11.2
chr14_+_29780113 14.86 ENSDART00000173195
zgc:153146
chr4_+_21717793 14.86 ENSDART00000040266
myogenic factor 6
chr20_+_34455645 14.73 ENSDART00000135789
methyltransferase like 11B
chr1_+_6171585 14.58 ENSDART00000024358
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr23_+_6077503 14.40 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr21_-_22951604 14.35 ENSDART00000083449
ENSDART00000180129
duboraya
chr23_-_9925568 14.23 ENSDART00000081268
si:ch211-220i18.4
chr8_-_32497815 14.15 ENSDART00000122359
si:dkey-164f24.2
chr17_-_20118145 14.13 ENSDART00000149737
ENSDART00000165606
ryanodine receptor 2b (cardiac)
chr20_-_36575475 13.80 ENSDART00000062893
enabled homolog (Drosophila)
chr24_+_20575259 13.54 ENSDART00000010488
kelch-like family member 40b
chr14_-_30366196 13.46 ENSDART00000007022
platelet-derived growth factor receptor-like
chr24_+_26276805 13.29 ENSDART00000089749
adiponectin, C1Q and collagen domain containing, a
chr7_+_22543963 13.13 ENSDART00000101528
cholinergic receptor, nicotinic, beta 1 (muscle)
chr5_-_48268049 13.11 ENSDART00000187454
myocyte enhancer factor 2cb
chr2_-_4496358 12.87 ENSDART00000158216
adiponectin, C1Q and collagen domain containing, b
chr3_+_26135502 12.49 ENSDART00000146979
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr12_-_19119176 12.45 ENSDART00000149180
aconitase 2, mitochondrial
chr3_-_50046004 12.43 ENSDART00000109544
si:ch1073-100f3.2
chr7_+_22718251 12.34 ENSDART00000027718
ENSDART00000143341
fragile X mental retardation, autosomal homolog 2
chr18_+_20494413 12.10 ENSDART00000060295
receptor-associated protein of the synapse, 43kD
chr8_-_32497581 11.96 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr2_+_6181383 11.55 ENSDART00000153307
si:ch73-344o19.1
chr25_+_5039050 11.49 ENSDART00000154700
parvin, beta
chr16_-_31475904 11.39 ENSDART00000145691
si:ch211-251p5.5
chr9_-_43073960 11.06 ENSDART00000059460
titin, tandem duplicate 2
chr14_+_30285613 10.92 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr9_-_48281941 10.91 ENSDART00000099787
kelch-like family member 41a
chr7_-_48263516 10.89 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr3_-_53114299 10.78 ENSDART00000109390

chr25_+_16945348 10.46 ENSDART00000016591
fibroblast growth factor 6a
chr6_-_20875111 10.11 ENSDART00000115118
ENSDART00000159916
tensin 1a
chr23_-_1557195 10.08 ENSDART00000136436
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr14_-_29906209 9.84 ENSDART00000192952
sorbin and SH3 domain containing 2b
chr14_-_21063977 9.45 ENSDART00000164373
si:dkey-74k8.3
chr15_-_9031996 9.34 ENSDART00000124998
reticulon 2a
chr19_-_38611814 9.05 ENSDART00000151958
collagen, type XVI, alpha 1
chr14_-_21064199 9.03 ENSDART00000172099
si:dkey-74k8.3
chr16_-_17541890 8.90 ENSDART00000131328
chloride channel, voltage-sensitive 1b
chr9_+_6578580 8.70 ENSDART00000061577
four and a half LIM domains 2a
chr19_+_44039849 8.31 ENSDART00000086040
leucine rich repeat containing 14B
chr8_+_45294767 8.30 ENSDART00000191527
ubiquitin associated protein 2b
chr20_+_6756247 8.18 ENSDART00000167344
insulin-like growth factor binding protein 3
chr12_+_10952794 8.14 ENSDART00000167090
retinoic acid receptor, alpha a
chr2_-_31791633 8.03 ENSDART00000180662
reticulophagy regulator 1
chr16_-_7228276 7.86 ENSDART00000149030
5'-nucleotidase, cytosolic IIIA
chr18_-_15467446 7.83 ENSDART00000187847
endonuclease, polyU-specific C
chr13_-_11536951 7.77 ENSDART00000018155
adenylosuccinate synthase
chr23_+_24926407 7.54 ENSDART00000137486
kelch-like family member 21
chr18_+_23218980 7.46 ENSDART00000185014
myocyte enhancer factor 2aa
chr14_+_22129096 7.29 ENSDART00000132514
cyclin G1
chr9_-_7673856 7.20 ENSDART00000102715
tubulin, alpha 8 like 3
chr16_+_31542645 7.03 ENSDART00000163724
Src like adaptor
chr22_-_22164338 6.56 ENSDART00000183840
cell division cycle 34 homolog (S. cerevisiae) a
chr9_+_24065855 6.53 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr18_+_23193567 6.46 ENSDART00000190072
ENSDART00000171594
ENSDART00000181762
myocyte enhancer factor 2aa
chr20_+_23173710 6.36 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr6_+_12462079 6.32 ENSDART00000192029
ENSDART00000065385
nuclear receptor subfamily 4, group A, member 2b
chr23_-_35347714 6.16 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr13_+_31757331 6.11 ENSDART00000044282
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr22_-_8509215 6.07 ENSDART00000140146
si:ch73-27e22.3
chr21_+_40589770 6.07 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pyruvate dehydrogenase kinase, isozyme 3b
chr18_+_23193820 6.06 ENSDART00000148106
myocyte enhancer factor 2aa
chr4_-_1720648 5.95 ENSDART00000103484
growth arrest-specific 2 like 3
chr3_+_59784632 5.94 ENSDART00000084729
platelet/endothelial cell adhesion molecule 1
chr9_+_31795343 5.90 ENSDART00000139584
integrin, beta-like 1
chr5_-_32505109 5.90 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr6_+_43450221 5.87 ENSDART00000075521
zgc:113054
chr20_-_39271844 5.83 ENSDART00000192708
clusterin
chr1_+_18965750 5.79 ENSDART00000132379
LIM and calponin homology domains 1a
chr2_-_23349116 5.79 ENSDART00000099690
family with sequence similarity 129, member Ab
chr6_+_3373665 5.71 ENSDART00000134133
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr2_+_20472150 5.63 ENSDART00000168537
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a
chr3_+_53511936 5.60 ENSDART00000177083
zmp:0000001048
chr12_+_23866368 5.53 ENSDART00000188652
ENSDART00000192478
supervillin a
chr5_+_51227147 5.31 ENSDART00000083340
UBA domain containing 1
chr13_-_42673978 5.28 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr25_-_16554757 5.20 ENSDART00000154480
si:ch211-266k8.6
chr20_+_18163821 5.17 ENSDART00000186507
aquaporin 4
chr7_-_30143092 5.02 ENSDART00000173636
FERM domain containing 5
chr16_+_5259886 4.99 ENSDART00000186668
plectin b
chr19_-_12648122 4.99 ENSDART00000151184
family with sequence similarity 210, member Aa
chr11_-_11336986 4.95 ENSDART00000016677
zgc:77929
chr4_-_72080351 4.92 ENSDART00000174925

chr6_+_11438972 4.85 ENSDART00000029314
collagen, type V, alpha 2b
chr22_+_20546612 4.84 ENSDART00000141852
si:dkey-172o19.2
chr8_+_4337312 4.82 ENSDART00000182228
myosin, light chain 2b, regulatory, cardiac, slow
chr6_-_25201810 4.72 ENSDART00000168683
leucine rich repeat containing 8 VRAC subunit C
chr13_-_28674422 4.69 ENSDART00000122754
ENSDART00000057574
5'-nucleotidase, cytosolic IIa
chr22_+_16497670 4.61 ENSDART00000014330
immediate early response 5
chr21_-_25685739 4.59 ENSDART00000129619
ENSDART00000101205
phosphorylase kinase, gamma 1b (muscle)
chr20_-_45423498 4.56 ENSDART00000098424
tribbles pseudokinase 2
chr6_-_46768040 4.41 ENSDART00000154071
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 2
chr15_-_506010 4.32 ENSDART00000155472
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr12_+_17106117 4.29 ENSDART00000149990
actin, alpha 2, smooth muscle, aorta
chr16_-_29557338 4.28 ENSDART00000058888
HORMA domain containing 1
chr1_-_49250490 4.21 ENSDART00000150386
si:ch73-6k14.2
chr8_-_13362757 4.02 ENSDART00000188608
coiled-coil domain containing 124
chr16_+_20895904 3.93 ENSDART00000052662
homeobox A13b
chr5_-_32505276 3.90 ENSDART00000034705
ENSDART00000187597
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr16_+_6021908 3.80 ENSDART00000163786

chr16_-_30570161 3.79 ENSDART00000184045
ENSDART00000191040
lamin A
chr15_-_31406093 3.79 ENSDART00000123444
odorant receptor, family D, subfamily 111, member 8
chr12_+_34119439 3.75 ENSDART00000032821
cytohesin 1b
chr1_-_43915423 3.52 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr7_+_17534485 3.47 ENSDART00000170911
novel immune-type receptor 1k
chr20_-_26066020 3.25 ENSDART00000078559
myc target 1a
chr14_-_15699528 3.24 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr20_+_19066858 3.12 ENSDART00000192086
SRY (sex determining region Y)-box 7
chr16_+_36748538 3.10 ENSDART00000139069
2,4-dienoyl CoA reductase 1, mitochondrial
chr5_+_51248784 3.05 ENSDART00000159571
ENSDART00000189513
ENSDART00000092285
mutS homolog 3 (E. coli)
chr1_+_13930625 3.04 ENSDART00000111026
nocturnin b
chr24_-_27409599 2.99 ENSDART00000041770
chemokine (C-C motif) ligand 34b, duplicate 3
chr9_-_48184823 2.99 ENSDART00000180264
kelch-like family member 23
chr24_+_21540842 2.92 ENSDART00000091529
WAS protein family, member 3b
chr20_+_13175379 2.90 ENSDART00000025644
protein phosphatase 2, regulatory subunit B', alpha isoform
chr11_+_25634041 2.88 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr16_+_41570653 2.87 ENSDART00000102665
asteroid homolog 1a
chr23_-_27506161 2.86 ENSDART00000145007
ankyrin repeat and SOCS box containing 8
chr22_-_13649588 2.85 ENSDART00000131877
si:ch211-279g13.1
chr12_-_35393211 2.82 ENSDART00000137139
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr4_+_33462238 2.80 ENSDART00000111083
si:dkey-247i3.1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2ca+mef2cb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 47.6 GO:0035988 chondrocyte proliferation(GO:0035988)
8.2 24.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
8.2 24.5 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
7.5 97.7 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
6.8 13.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
6.5 25.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
6.3 25.0 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
6.1 54.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
4.9 54.0 GO:0048769 sarcomerogenesis(GO:0048769)
4.8 14.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
4.6 13.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
4.5 36.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
4.5 31.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
4.5 22.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
3.7 18.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
3.4 54.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
3.2 15.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
3.1 12.5 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
2.8 24.8 GO:0086003 cardiac muscle cell contraction(GO:0086003)
2.7 75.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
2.5 12.4 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
2.3 34.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
2.2 10.9 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
2.0 68.4 GO:0050821 protein stabilization(GO:0050821)
1.7 28.3 GO:0034629 cellular protein complex localization(GO:0034629)
1.5 20.7 GO:0090303 positive regulation of wound healing(GO:0090303)
1.4 4.3 GO:0090131 mesenchyme migration(GO:0090131)
1.4 4.3 GO:0060631 regulation of meiosis I(GO:0060631)
1.4 41.2 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
1.3 205.6 GO:0006936 muscle contraction(GO:0006936)
1.1 41.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
1.0 3.0 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
1.0 25.5 GO:0070593 dendrite self-avoidance(GO:0070593)
1.0 21.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.0 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.9 20.3 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.9 21.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.8 5.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.8 8.0 GO:0061709 reticulophagy(GO:0061709)
0.8 49.8 GO:0006096 glycolytic process(GO:0006096)
0.8 2.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.7 8.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.7 5.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.7 11.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.7 2.0 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.7 13.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.6 3.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.6 3.8 GO:0090342 regulation of cell aging(GO:0090342)
0.6 13.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.6 16.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.6 26.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.6 5.2 GO:0006833 water transport(GO:0006833)
0.6 14.1 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.5 5.6 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.5 44.4 GO:0030239 myofibril assembly(GO:0030239)
0.5 2.4 GO:0030242 pexophagy(GO:0030242)
0.5 5.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.5 1.8 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.5 1.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.8 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.4 2.6 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.4 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 56.9 GO:0006821 chloride transport(GO:0006821)
0.4 7.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.4 121.7 GO:0061061 muscle structure development(GO:0061061)
0.4 13.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 2.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.3 1.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 2.8 GO:0044805 late nucleophagy(GO:0044805)
0.3 8.1 GO:0032526 response to retinoic acid(GO:0032526)
0.3 6.1 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.3 1.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.3 14.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.3 0.8 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.3 6.1 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.2 2.4 GO:1901571 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.2 0.9 GO:2001244 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 31.3 GO:0021782 glial cell development(GO:0021782)
0.2 4.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 0.8 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 5.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 2.9 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 5.5 GO:0051014 actin filament severing(GO:0051014)
0.2 17.2 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.2 2.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 108.6 GO:0016567 protein ubiquitination(GO:0016567)
0.2 2.1 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 7.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 2.2 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 12.1 GO:0007416 synapse assembly(GO:0007416)
0.1 1.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 15.7 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 5.8 GO:1901214 regulation of neuron death(GO:1901214)
0.1 1.9 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 1.9 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 5.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.8 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 1.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 12.2 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 3.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 3.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.0 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 1.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 5.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 3.1 GO:0001570 vasculogenesis(GO:0001570)
0.1 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 1.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.9 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 0.9 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.2 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.0 GO:0043486 histone exchange(GO:0043486)
0.0 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 2.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 3.9 GO:0033333 fin development(GO:0033333)
0.0 5.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 302.1 GO:0031430 M band(GO:0031430)
4.4 43.6 GO:0031672 A band(GO:0031672)
4.0 15.9 GO:0008290 F-actin capping protein complex(GO:0008290)
3.7 25.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.4 41.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
3.1 12.3 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
3.0 139.7 GO:0031941 filamentous actin(GO:0031941)
3.0 20.7 GO:0016012 sarcoglycan complex(GO:0016012)
2.6 54.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.8 121.8 GO:0030018 Z disc(GO:0030018)
1.6 93.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
1.4 5.8 GO:0016460 myosin II complex(GO:0016460)
1.2 4.9 GO:0005588 collagen type V trimer(GO:0005588)
1.2 20.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.1 13.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.9 28.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8 23.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 24.9 GO:0016605 PML body(GO:0016605)
0.6 76.1 GO:0016459 myosin complex(GO:0016459)
0.6 5.8 GO:0042583 chromaffin granule(GO:0042583)
0.6 38.2 GO:0034707 chloride channel complex(GO:0034707)
0.5 2.4 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5 7.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 5.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 5.0 GO:0030056 hemidesmosome(GO:0030056)
0.3 24.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 3.0 GO:0032300 mismatch repair complex(GO:0032300)
0.3 1.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 4.3 GO:0005869 dynactin complex(GO:0005869)
0.2 4.8 GO:0005921 gap junction(GO:0005921)
0.2 0.8 GO:0097519 DNA recombinase complex(GO:0097519)
0.2 2.9 GO:0031209 SCAR complex(GO:0031209)
0.2 20.3 GO:0030055 cell-substrate junction(GO:0030055)
0.2 7.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 13.7 GO:0005581 collagen trimer(GO:0005581)
0.1 11.1 GO:0005814 centriole(GO:0005814)
0.1 1.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 1.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818)
0.1 2.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 4.0 GO:0030496 midbody(GO:0030496)
0.1 1.7 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 24.7 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 20.5 GO:0005739 mitochondrion(GO:0005739)
0.0 1.9 GO:0099572 postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 34.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
8.3 49.8 GO:0004743 pyruvate kinase activity(GO:0004743)
8.2 24.5 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
7.5 97.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
6.6 131.7 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
6.2 24.9 GO:0005521 lamin binding(GO:0005521)
4.6 18.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
4.2 12.5 GO:0003994 aconitate hydratase activity(GO:0003994)
4.0 12.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
3.6 79.9 GO:0005523 tropomyosin binding(GO:0005523)
3.5 52.4 GO:0051879 Hsp90 protein binding(GO:0051879)
2.8 14.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
2.5 12.4 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
2.1 20.7 GO:0016936 galactoside binding(GO:0016936)
2.1 24.6 GO:0030544 Hsp70 protein binding(GO:0030544)
2.0 10.1 GO:2001070 starch binding(GO:2001070)
1.7 57.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.5 4.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
1.5 41.3 GO:0016208 AMP binding(GO:0016208)
1.5 20.3 GO:2001069 glycogen binding(GO:2001069)
1.4 5.8 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
1.4 5.6 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
1.4 13.8 GO:0005522 profilin binding(GO:0005522)
1.1 19.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.9 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.9 4.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.8 309.1 GO:0051015 actin filament binding(GO:0051015)
0.8 5.7 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.8 3.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.8 6.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 8.2 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.7 12.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7 5.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.7 2.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.7 33.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.6 6.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 5.2 GO:0015250 water channel activity(GO:0015250)
0.6 16.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 13.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.5 36.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.5 37.7 GO:0005254 chloride channel activity(GO:0005254)
0.5 1.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 9.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 2.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.4 1.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 11.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 35.2 GO:0043130 ubiquitin binding(GO:0043130)
0.3 32.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 21.7 GO:0019902 phosphatase binding(GO:0019902)
0.3 1.6 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.3 2.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 1.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 6.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 12.3 GO:0045182 translation regulator activity(GO:0045182)
0.3 5.9 GO:0048038 quinone binding(GO:0048038)
0.3 8.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 2.9 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 1.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 7.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.8 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.2 52.8 GO:0003779 actin binding(GO:0003779)
0.2 4.8 GO:0022829 wide pore channel activity(GO:0022829)
0.2 80.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 15.6 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.2 2.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 19.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.6 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 1.1 GO:0016917 G-protein coupled GABA receptor activity(GO:0004965) GABA receptor activity(GO:0016917)
0.1 15.6 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 5.9 GO:0005178 integrin binding(GO:0005178)
0.1 1.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 7.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 103.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 14.7 GO:0008083 growth factor activity(GO:0008083)
0.1 2.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 3.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 7.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 15.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 2.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 6.9 GO:0015631 tubulin binding(GO:0015631)
0.0 3.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.9 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 35.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 13.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 9.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 8.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 8.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 11.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 7.6 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 5.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 7.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.9 PID BMP PATHWAY BMP receptor signaling
0.1 3.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 34.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.1 8.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.0 8.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.8 11.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.8 9.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.7 12.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.7 12.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 7.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 14.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 4.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 9.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 3.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 5.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.7 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production