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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mafb+mafba+nrl

Z-value: 2.26

Motif logo

Transcription factors associated with mafb+mafba+nrl

Gene Symbol Gene ID Gene Info
ENSDARG00000017121 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
ENSDARG00000076520 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
ENSDARG00000100466 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafbadr11_v1_chr23_-_3408777_34087770.463.8e-06Click!
mafbdr11_v1_chr25_+_36674715_36674715-0.251.6e-02Click!

Activity profile of mafb+mafba+nrl motif

Sorted Z-values of mafb+mafba+nrl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1291012 29.66 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr6_-_60147517 27.91 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_-_14052349 23.98 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr19_-_5254699 19.78 ENSDART00000081951
syntaxin 1B
chr10_-_7858553 19.06 ENSDART00000182010
inositol polyphosphate-5-phosphatase Ja
chr24_-_4973765 17.72 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr25_-_3503164 16.47 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
si:ch211-272n13.7
chr6_+_58543336 15.31 ENSDART00000157018
stathmin-like 3
chr7_-_26087807 15.29 ENSDART00000052989
acetylcholinesterase
chr9_-_296169 15.12 ENSDART00000165228
kinesin family member 5A, a
chr4_+_26496489 14.93 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr14_+_33458294 14.79 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr17_-_37214196 14.66 ENSDART00000128715
kinesin family member 3Cb
chr15_+_16897554 14.51 ENSDART00000154679
yippee-like 2b
chr2_-_44720551 14.43 ENSDART00000146380
MAP6 domain containing 1
chr6_-_24358732 14.35 ENSDART00000159595
epoxide hydrolase 4
chr7_+_23875269 14.32 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr1_-_21344478 14.12 ENSDART00000077805
glutamate receptor, ionotropic, AMPA 2a
chr4_+_19534833 13.57 ENSDART00000140028
leucine rich repeat containing 4.1
chr23_+_45579497 13.37 ENSDART00000110381
early growth response 4
chr14_+_49135264 13.23 ENSDART00000084119
si:ch1073-44g3.1
chr14_-_30642819 12.85 ENSDART00000078154
neuronal PAS domain protein 4a
chr5_-_28915130 12.82 ENSDART00000078592
neural proliferation, differentiation and control, 1b
chr21_+_41697552 12.82 ENSDART00000169511
protein phosphatase 2, regulatory subunit B, beta b
chr17_+_9310259 12.72 ENSDART00000186158
ENSDART00000190329
neuronal PAS domain protein 3
chr7_-_24699985 12.64 ENSDART00000052802
calbindin 2b
chr20_+_88168 12.57 ENSDART00000149283
zgc:112001
chr23_+_21067684 12.55 ENSDART00000132066
potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
chr6_-_13188667 12.31 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr4_+_8797197 12.29 ENSDART00000158671
sulfotransferase family 4A, member 1
chr8_+_24854600 12.17 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr9_-_44295071 12.16 ENSDART00000011837
neuronal differentiation 1
chr21_-_31143903 12.12 ENSDART00000111571
RAP1 GTPase activating protein 2b
chr19_+_23982466 12.09 ENSDART00000080673
synaptotagmin XIa
chr7_-_38612230 12.09 ENSDART00000173678
C1q and TNF related 4
chr22_-_38543630 12.08 ENSDART00000172029
si:ch211-126j24.1
chr22_+_18816662 12.01 ENSDART00000132476
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr7_+_58686860 11.99 ENSDART00000052332
proenkephalin b
chr25_+_19999623 11.79 ENSDART00000026401
zgc:194665
chr8_+_53464216 11.72 ENSDART00000169514
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr1_+_49266886 11.16 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr23_-_26077038 11.02 ENSDART00000126299
GDP dissociation inhibitor 1
chr23_-_11870962 11.02 ENSDART00000143481
si:dkey-178k16.1
chr17_-_12385308 11.00 ENSDART00000080927
synaptosomal-associated protein, 25b
chr16_-_44349845 10.98 ENSDART00000170932
regulating synaptic membrane exocytosis 2a
chr18_-_1228688 10.63 ENSDART00000064403
neuroplastin b
chr5_-_21030934 10.47 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr5_-_12524996 10.42 ENSDART00000142258
si:ch73-263f13.1
chr25_-_4482449 10.40 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr16_-_12984631 10.23 ENSDART00000184863
calcium channel, voltage-dependent, gamma subunit 7b
chr13_-_27038407 10.23 ENSDART00000146712
coiled-coil domain containing 85A
chr5_+_36614196 10.20 ENSDART00000150574
neuro-oncological ventral antigen 1
chr1_+_7679328 10.00 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr21_+_42226113 9.98 ENSDART00000170362
gamma-aminobutyric acid type A receptor beta2 subunit
chr5_-_12525441 9.97 ENSDART00000177490
ENSDART00000164190
kinase suppressor of ras 2
chr17_-_12336987 9.95 ENSDART00000172001
synaptosomal-associated protein, 25b
chr8_-_4596662 9.94 ENSDART00000138199
septin 5a
chr2_+_6926100 9.91 ENSDART00000153289
nitric oxide synthase 1 (neuronal) adaptor protein b
chr4_-_8882572 9.82 ENSDART00000190060
metallophosphoesterase domain containing 1
chr19_+_233143 9.73 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr7_+_19882066 9.58 ENSDART00000111144
transmembrane protein 151A
chr15_-_47937204 9.55 ENSDART00000154705
si:ch1073-111c8.3
chr13_+_3954540 9.54 ENSDART00000092646
leucine rich repeat containing 73
chr23_-_7799184 9.34 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr22_-_600016 9.32 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr10_+_20108557 9.31 ENSDART00000142708
dematin actin binding protein
chr19_+_37925616 9.24 ENSDART00000148348
neurexophilin 1
chr19_-_9882821 9.14 ENSDART00000147128
calcium channel, voltage-dependent, gamma subunit 7a
chr17_-_48915427 9.12 ENSDART00000054781
galectin 8b
chr20_-_54462551 9.12 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr8_+_29267093 9.08 ENSDART00000077647
glutamate receptor, ionotropic, delta 2
chr20_-_34801181 9.06 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr24_-_27400017 8.99 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr10_+_44641599 8.95 ENSDART00000172128
seizure related 6 homolog (mouse)-like
chr18_-_85294 8.92 ENSDART00000044387
GA binding protein transcription factor, beta subunit 1
chr8_-_23416362 8.85 ENSDART00000063005
G protein-coupled receptor 173
chr23_-_3674443 8.65 ENSDART00000134830
ENSDART00000057422
protein kinase C and casein kinase substrate in neurons 1a
chr2_-_9059955 8.64 ENSDART00000022768
adenylate kinase 5
chr9_-_23217196 8.53 ENSDART00000083567
kinesin family member 5C
chr13_-_35051897 8.49 ENSDART00000129559
BTB (POZ) domain containing 3b
chr14_-_2206476 8.47 ENSDART00000081870
protocadherin 2 alpha b 6
chr21_-_45588720 8.46 ENSDART00000186642
ENSDART00000189531

chr24_-_29997145 8.45 ENSDART00000135094
palmdelphin b
chr19_-_9712530 8.43 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr5_-_22501663 8.41 ENSDART00000133174
si:dkey-27p18.5
chr16_+_34528409 8.33 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr20_-_31905968 8.32 ENSDART00000142806
syntaxin binding protein 5a (tomosyn)
chr1_+_29858032 8.29 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr16_+_10346277 8.19 ENSDART00000081092
si:dkeyp-77h1.4
chr1_-_59251874 8.16 ENSDART00000168919
olfactomedin 2b
chr17_+_19630272 8.15 ENSDART00000104895
regulator of G protein signaling 7a
chr8_-_7232413 8.15 ENSDART00000092426
glutamate receptor interacting protein 2a
chr4_-_21851473 8.14 ENSDART00000019748
lin-7 homolog A (C. elegans)
chr6_-_15604157 8.13 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr6_+_41255485 8.11 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr24_+_39129316 8.07 ENSDART00000155346
TBC1 domain family, member 24
chr25_-_3503458 8.04 ENSDART00000173269
si:ch211-272n13.7
chr5_+_45976130 7.95 ENSDART00000175670
synaptic vesicle glycoprotein 2C
chr2_+_47623202 7.94 ENSDART00000154465
si:ch211-165b10.3
chr17_-_43286903 7.94 ENSDART00000176637
si:dkey-1f12.3
chr5_-_32092856 7.87 ENSDART00000086181
ENSDART00000181677
calcium binding protein 7b
chr24_-_35707552 7.87 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr21_-_34658266 7.86 ENSDART00000023038
dachshund a
chr17_-_7861219 7.83 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr7_-_35710263 7.80 ENSDART00000043857
iroquois homeobox 5a
chr14_-_44841503 7.78 ENSDART00000179114
si:dkey-109l4.6
chr18_+_22793465 7.76 ENSDART00000149685
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr13_-_11644806 7.76 ENSDART00000169953
dynactin 1b
chr5_-_70625697 7.74 ENSDART00000179538
ENSDART00000190540

chr23_-_14990865 7.74 ENSDART00000147799
ndrg family member 3b
chr21_+_15870752 7.71 ENSDART00000122015
family with sequence similarity 169, member Ab
chr3_-_30118856 7.71 ENSDART00000109953
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_+_54673846 7.70 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr5_+_30624183 7.70 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr6_-_15604417 7.65 ENSDART00000157817
leucine rich repeat (in FLII) interacting protein 1b
chr9_+_30890549 7.62 ENSDART00000101070
dachshund d
chr23_+_6272638 7.56 ENSDART00000190366
synaptotagmin IIa
chr10_-_26744131 7.50 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr17_-_22021213 7.49 ENSDART00000078843
zmp:0000001102
chr25_-_29134654 7.47 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr3_-_19133003 7.42 ENSDART00000145215
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr8_+_50983551 7.37 ENSDART00000142061
si:dkey-32e23.4
chr3_-_18711288 7.36 ENSDART00000183885
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr1_+_11691722 7.30 ENSDART00000134531
eukaryotic translation initiation factor 3, subunit Bb
chr6_-_43092175 7.29 ENSDART00000084389
leucine rich repeat neuronal 1
chr12_-_29624638 7.28 ENSDART00000126744
neuregulin 3b
chr14_-_32403554 7.26 ENSDART00000172873
ENSDART00000173408
ENSDART00000173114
ENSDART00000185594
ENSDART00000186762
ENSDART00000010982
fibroblast growth factor 13a
chr5_+_57743815 7.22 ENSDART00000005090
ALG9, alpha-1,2-mannosyltransferase
chr20_+_51312883 7.22 ENSDART00000084186
transmembrane protein 151Ba
chr3_+_20156956 7.22 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr21_-_23475361 7.20 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr2_+_31957554 7.17 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr23_-_29667544 7.10 ENSDART00000059339
calsyntenin 1
chr21_+_26726936 7.06 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr7_+_53541173 7.06 ENSDART00000159449
GRAM domain containing 2Aa
chr3_-_61203203 7.06 ENSDART00000171787
parvalbumin 1
chr4_-_27350820 7.05 ENSDART00000145806
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr17_+_29345606 7.01 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr4_+_10888762 6.89 ENSDART00000136049
synaptotagmin X
chr10_+_39164638 6.89 ENSDART00000188997

chr4_-_191736 6.78 ENSDART00000169187
ENSDART00000192054
protein tyrosine phosphatase, receptor type, O
chr8_-_18200003 6.72 ENSDART00000080014
ribosomal protein S8b
chr20_-_20931197 6.69 ENSDART00000152726
BTB (POZ) domain containing 6b
chr1_+_29281764 6.68 ENSDART00000112106
family with sequence similarity 155, member A
chr23_-_44494401 6.62 ENSDART00000114640
ENSDART00000148532
actin-like 6B
chr2_-_24444838 6.61 ENSDART00000147885
ENSDART00000164720
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr21_-_43015383 6.60 ENSDART00000065097
dihydropyrimidinase-like 3
chr7_-_38477235 6.57 ENSDART00000084355
zgc:165481
chr22_-_22416337 6.53 ENSDART00000142947
ENSDART00000089569
calmodulin regulated spectrin-associated protein family, member 2a
chr20_-_37629084 6.53 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr1_-_20271138 6.46 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_+_38344 6.42 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr6_-_58828398 6.42 ENSDART00000090634
kinesin family member 5A, b
chr14_-_2050057 6.26 ENSDART00000112875
protocadherin beta 15
chr14_+_34547554 6.26 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr14_+_3449780 6.25 ENSDART00000163849
transient receptor potential cation channel, subfamily C, member 3
chr20_-_53981626 6.22 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr6_-_10776254 6.22 ENSDART00000184008
G protein-coupled receptor 155b
chr19_-_27261102 6.18 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr1_+_1599979 6.17 ENSDART00000097626
urotensin II-related peptide
chr22_-_38360205 6.16 ENSDART00000162055
MAP/microtubule affinity-regulating kinase 1
chr22_+_17359346 6.13 ENSDART00000145434
G protein-coupled receptor 52
chr1_-_25438934 6.07 ENSDART00000111686
FH2 domain containing 1
chr25_+_13791627 6.07 ENSDART00000159278
zgc:92873
chr18_+_14477740 6.07 ENSDART00000146472
potassium voltage-gated channel, subfamily G, member 4a
chr8_+_25254435 6.06 ENSDART00000143554
adenosine monophosphate deaminase 2b
chr24_+_32472155 6.04 ENSDART00000098859
neuronal differentiation 6a
chr23_-_28141419 6.02 ENSDART00000133039
tachykinin 3a
chr13_-_11035420 6.00 ENSDART00000108709
centrosomal protein 170Aa
chr9_-_54840124 5.98 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr23_+_6795531 5.98 ENSDART00000092131
si:ch211-117c9.5
chr4_-_19028861 5.97 ENSDART00000166374
si:dkey-31f5.11
chr21_+_53504 5.94 ENSDART00000170452
dimethylglycine dehydrogenase
chr20_-_45661049 5.90 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr24_+_24461558 5.86 ENSDART00000182424
basic helix-loop-helix family, member e22
chr11_+_30161168 5.84 ENSDART00000157385
cyclin-dependent kinase-like 5
chr19_-_7358184 5.82 ENSDART00000092379
oxidation resistance 1b
chr10_+_44581378 5.82 ENSDART00000190331
seizure related 6 homolog (mouse)-like
chr10_+_20113830 5.80 ENSDART00000139722
dematin actin binding protein
chr23_-_14918276 5.80 ENSDART00000179831
ndrg family member 3b
chr9_+_53707240 5.79 ENSDART00000171490
si:ch211-199f5.1
chr23_+_35713557 5.74 ENSDART00000123518
tubulin, alpha 1c
chr17_-_42218652 5.71 ENSDART00000081396
ENSDART00000190007
NK2 homeobox 2a
chr19_-_7321221 5.69 ENSDART00000092375
oxidation resistance 1b
chr7_+_50766094 5.69 ENSDART00000165037
si:ch73-380l10.2
chr14_-_32503363 5.68 ENSDART00000034883
MCF.2 cell line derived transforming sequence a
chr1_-_11973341 5.68 ENSDART00000159981
ENSDART00000066638
G protein-coupled receptor kinase 4
chr5_+_39994283 5.67 ENSDART00000112728
transmembrane protein 175
chr14_-_18671334 5.66 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr15_-_47193564 5.66 ENSDART00000172453
limbic system-associated membrane protein
chr20_-_53321499 5.64 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
WAS protein family, member 1
chr5_+_43965078 5.63 ENSDART00000113502
ENSDART00000187143
si:dkey-84j12.1
chr12_-_26383242 5.61 ENSDART00000152941
ubiquitin specific peptidase 54b
chr20_-_40717900 5.61 ENSDART00000181663
connexin 43
chr12_+_42574148 5.60 ENSDART00000157855
early B cell factor 3a
chr23_-_45049044 5.58 ENSDART00000067630
SH3 domain containing GRB2 like 2, endophilin A1
chr13_-_39254 5.57 ENSDART00000093222
general transcription factor IIA, 1-like
chr3_-_35801146 5.56 ENSDART00000150911
CASK interacting protein 1
chr1_-_25438737 5.55 ENSDART00000134470
FH2 domain containing 1
chr23_-_18057851 5.48 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287

Network of associatons between targets according to the STRING database.

First level regulatory network of mafb+mafba+nrl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 30.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
4.1 12.2 GO:0015824 proline transport(GO:0015824)
4.0 19.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.8 15.3 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
3.5 27.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
3.2 12.6 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
2.6 12.9 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
2.5 7.6 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
2.5 17.7 GO:0021534 cell proliferation in hindbrain(GO:0021534)
2.5 19.8 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.4 7.2 GO:0021961 posterior commissure morphogenesis(GO:0021961)
2.3 9.3 GO:0003322 pancreatic A cell development(GO:0003322)
2.1 12.5 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
1.9 5.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.9 5.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.8 7.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.8 5.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.7 12.0 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
1.6 8.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.5 6.2 GO:0035095 behavioral response to nicotine(GO:0035095)
1.5 4.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
1.5 21.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.5 5.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.5 7.4 GO:1903146 regulation of mitophagy(GO:1903146)
1.4 5.7 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
1.3 4.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.3 12.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.2 6.2 GO:0046677 response to antibiotic(GO:0046677)
1.2 6.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 8.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
1.1 19.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
1.1 5.4 GO:0032289 central nervous system myelin formation(GO:0032289)
1.1 14.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.0 7.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
1.0 10.4 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
1.0 7.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
1.0 2.9 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.9 4.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.9 7.3 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.9 7.9 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.9 11.2 GO:0048899 anterior lateral line development(GO:0048899)
0.8 18.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 6.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.8 5.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.8 10.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 14.1 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.8 16.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.8 4.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 3.8 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.7 5.9 GO:0043584 nose development(GO:0043584)
0.7 20.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.7 12.7 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.7 2.7 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.7 0.7 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 4.5 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 3.8 GO:0021767 mammillary body development(GO:0021767)
0.6 30.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.6 4.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.6 8.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.6 2.5 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 10.0 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.6 6.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 11.7 GO:0008354 germ cell migration(GO:0008354)
0.6 18.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.6 13.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.6 1.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 3.4 GO:1903826 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.6 3.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.6 2.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.5 2.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.5 4.9 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.5 5.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.5 9.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.5 8.9 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.5 3.6 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.5 5.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.5 1.5 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.5 13.1 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.5 19.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.5 3.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.5 3.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.5 3.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.5 3.8 GO:0035094 response to nicotine(GO:0035094)
0.5 12.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.5 6.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 3.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.4 6.1 GO:0032264 IMP salvage(GO:0032264)
0.4 1.3 GO:0015872 dopamine transport(GO:0015872) norepinephrine transport(GO:0015874)
0.4 5.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 1.7 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.4 1.6 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.4 1.6 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.4 5.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.4 3.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 2.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 17.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.4 2.3 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.4 3.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4 1.2 GO:2000638 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.4 2.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.4 1.1 GO:0051099 positive regulation of DNA binding(GO:0043388) positive regulation of binding(GO:0051099)
0.4 1.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.4 1.8 GO:0010586 miRNA metabolic process(GO:0010586)
0.4 2.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.4 8.3 GO:0001556 oocyte maturation(GO:0001556)
0.4 3.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.4 2.8 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.4 4.6 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.4 71.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.3 4.5 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 1.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 1.4 GO:0021742 abducens nucleus development(GO:0021742)
0.3 1.0 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 1.6 GO:0035608 protein deglutamylation(GO:0035608)
0.3 3.2 GO:0061709 reticulophagy(GO:0061709)
0.3 7.7 GO:0051289 protein homotetramerization(GO:0051289)
0.3 9.6 GO:0043967 histone H4 acetylation(GO:0043967)
0.3 2.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.3 11.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 7.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 2.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.3 1.5 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.3 2.7 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.3 3.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 3.8 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 1.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 7.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 9.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.3 3.9 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.0 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.2 1.0 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.2 6.8 GO:0051923 sulfation(GO:0051923)
0.2 7.7 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.2 3.1 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.2 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 0.9 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.2 4.8 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 21.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 2.5 GO:0007608 sensory perception of smell(GO:0007608)
0.2 4.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 5.1 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 16.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.2 1.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 4.1 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 6.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.2 8.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 6.8 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.2 2.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 2.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 1.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.2 2.2 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 7.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 11.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 5.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 34.3 GO:0006814 sodium ion transport(GO:0006814)
0.2 1.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 16.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 2.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 0.4 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.2 1.0 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.2 1.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 3.2 GO:0007020 microtubule nucleation(GO:0007020)
0.2 6.2 GO:0003094 glomerular filtration(GO:0003094)
0.2 3.7 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.2 4.9 GO:0050890 cognition(GO:0050890)
0.2 5.4 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.2 2.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 5.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 5.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.9 GO:0051030 snRNA transport(GO:0051030)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 3.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 7.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 2.0 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 18.9 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 2.3 GO:0030225 macrophage differentiation(GO:0030225)
0.1 1.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 2.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 2.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.1 1.7 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.5 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 1.4 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.1 0.4 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.7 GO:0030431 sleep(GO:0030431)
0.1 3.8 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.7 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 0.4 GO:0002698 negative regulation of immune effector process(GO:0002698)
0.1 5.2 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 11.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 3.1 GO:0043171 peptide catabolic process(GO:0043171)
0.1 3.8 GO:1903038 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.1 2.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 2.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 9.1 GO:0051260 protein homooligomerization(GO:0051260)
0.1 1.1 GO:1905145 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 2.0 GO:0043486 histone exchange(GO:0043486)
0.1 2.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 2.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 3.9 GO:0007098 centrosome cycle(GO:0007098)
0.1 18.5 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 11.1 GO:0007018 microtubule-based movement(GO:0007018)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 1.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 6.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 5.1 GO:0006887 exocytosis(GO:0006887)
0.1 3.1 GO:0016573 histone acetylation(GO:0016573)
0.1 0.8 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 3.4 GO:0055072 iron ion homeostasis(GO:0055072)
0.1 0.5 GO:0030719 P granule organization(GO:0030719)
0.1 3.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 3.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 1.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 2.2 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 1.3 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0044550 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.0 3.5 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 2.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.8 GO:0060021 palate development(GO:0060021)
0.0 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.2 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 2.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 1.9 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 3.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.7 GO:0001878 response to yeast(GO:0001878)
0.0 1.5 GO:0044782 cilium organization(GO:0044782)
0.0 1.3 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600) regulation of glucose import(GO:0046324)
0.0 0.8 GO:0048794 swim bladder development(GO:0048794)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 5.4 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.9 GO:0048881 mechanosensory lateral line system development(GO:0048881)
0.0 0.3 GO:0043200 response to amino acid(GO:0043200) cellular response to amino acid stimulus(GO:0071230)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 4.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0035794 positive regulation of mitochondrial membrane permeability(GO:0035794) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 0.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.7 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 1.3 GO:0048511 rhythmic process(GO:0048511)
0.0 2.7 GO:0006470 protein dephosphorylation(GO:0006470)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 21.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.0 8.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.9 5.8 GO:0032839 dendrite cytoplasm(GO:0032839)
1.9 27.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.5 7.6 GO:0042584 chromaffin granule membrane(GO:0042584)
1.5 14.8 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
1.5 5.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.4 5.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.3 7.7 GO:0070062 extracellular exosome(GO:0070062)
1.2 65.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
1.1 14.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.0 25.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.9 7.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.8 14.6 GO:0005801 cis-Golgi network(GO:0005801)
0.8 6.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.7 21.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 1.9 GO:1990745 EARP complex(GO:1990745)
0.6 54.6 GO:0005871 kinesin complex(GO:0005871)
0.6 16.3 GO:0035371 microtubule plus-end(GO:0035371)
0.6 3.7 GO:0005955 calcineurin complex(GO:0005955)
0.6 16.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.6 15.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 4.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.5 19.8 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.5 5.2 GO:1990752 microtubule minus-end(GO:0036449) microtubule end(GO:1990752)
0.5 2.5 GO:0000938 GARP complex(GO:0000938)
0.5 2.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.5 3.6 GO:0016586 RSC complex(GO:0016586)
0.4 7.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 7.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 15.2 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.4 1.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 22.1 GO:0030426 growth cone(GO:0030426)
0.4 6.2 GO:0043209 myelin sheath(GO:0043209)
0.4 2.8 GO:0070552 BRISC complex(GO:0070552)
0.3 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 2.0 GO:0000812 Swr1 complex(GO:0000812)
0.3 1.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 5.0 GO:0036038 MKS complex(GO:0036038)
0.3 21.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 7.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 1.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 23.1 GO:0001726 ruffle(GO:0001726)
0.3 6.3 GO:0035102 PRC1 complex(GO:0035102)
0.3 2.9 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.3 3.9 GO:0031209 SCAR complex(GO:0031209)
0.3 0.8 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.3 6.7 GO:0000145 exocyst(GO:0000145)
0.3 16.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 8.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.3 1.8 GO:0035517 PR-DUB complex(GO:0035517)
0.2 3.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 39.5 GO:0070382 exocytic vesicle(GO:0070382)
0.2 2.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 14.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 7.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 1.9 GO:0070449 elongin complex(GO:0070449)
0.2 6.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.9 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 3.4 GO:0030427 site of polarized growth(GO:0030427)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.4 GO:0030008 TRAPP complex(GO:0030008)
0.2 4.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 13.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 0.5 GO:0033391 chromatoid body(GO:0033391)
0.2 12.0 GO:0099503 secretory vesicle(GO:0099503)
0.2 25.7 GO:0045202 synapse(GO:0045202)
0.2 6.7 GO:0031201 SNARE complex(GO:0031201)
0.1 1.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 6.4 GO:0034703 cation channel complex(GO:0034703)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 6.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.6 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.9 GO:0034399 nuclear periphery(GO:0034399)
0.1 2.0 GO:0045180 basal cortex(GO:0045180)
0.1 2.6 GO:0005921 gap junction(GO:0005921)
0.1 0.5 GO:0034657 GID complex(GO:0034657)
0.1 2.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 0.4 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 61.7 GO:0043005 neuron projection(GO:0043005)
0.1 2.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 6.4 GO:0005814 centriole(GO:0005814)
0.1 1.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.1 GO:0030496 midbody(GO:0030496)
0.1 2.7 GO:0036452 ESCRT complex(GO:0036452)
0.1 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 7.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.1 17.5 GO:0005768 endosome(GO:0005768)
0.1 4.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 6.7 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 5.4 GO:0005884 actin filament(GO:0005884)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 2.9 GO:0005930 axoneme(GO:0005930)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.2 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 19.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0098802 plasma membrane receptor complex(GO:0098802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
2.6 12.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.5 15.3 GO:0004104 cholinesterase activity(GO:0004104)
2.5 19.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
2.1 27.9 GO:0015295 solute:proton symporter activity(GO:0015295)
2.0 8.1 GO:0097016 L27 domain binding(GO:0097016)
1.9 5.6 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
1.9 53.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.7 9.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.5 4.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.5 12.0 GO:0031628 opioid receptor binding(GO:0031628)
1.5 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.5 5.9 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.4 7.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.4 7.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
1.4 4.1 GO:0043621 protein self-association(GO:0043621)
1.1 5.5 GO:0015288 porin activity(GO:0015288)
1.0 7.2 GO:0005035 death receptor activity(GO:0005035)
1.0 12.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.0 5.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.0 3.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.9 54.0 GO:0044325 ion channel binding(GO:0044325)
0.9 14.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.9 9.1 GO:0005522 profilin binding(GO:0005522)
0.8 6.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8 11.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 6.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.8 2.3 GO:0046978 TAP1 binding(GO:0046978)
0.7 5.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.7 6.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 14.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 22.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6 5.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.6 44.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 12.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.6 3.7 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.6 29.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.6 5.2 GO:0030507 spectrin binding(GO:0030507)
0.6 4.0 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.6 3.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 6.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 6.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.6 6.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 3.8 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.5 4.3 GO:0001006 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.5 9.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.5 12.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.5 4.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.5 3.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 14.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 4.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 16.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 2.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 3.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 9.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 1.3 GO:0005329 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.4 3.9 GO:0004359 glutaminase activity(GO:0004359)
0.4 3.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 3.3 GO:0031419 cobalamin binding(GO:0031419)
0.4 2.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.4 9.5 GO:0030371 translation repressor activity(GO:0030371)
0.4 2.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.4 1.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.4 12.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 2.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.4 11.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 5.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.4 4.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 1.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 19.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 4.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 4.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 4.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 2.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.3 2.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 6.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.3 23.8 GO:0003777 microtubule motor activity(GO:0003777)
0.3 5.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 4.3 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.3 1.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 0.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 0.8 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.3 2.1 GO:0015232 heme transporter activity(GO:0015232)
0.3 4.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 2.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 4.3 GO:0045159 myosin II binding(GO:0045159)
0.2 5.7 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.2 5.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 4.0 GO:0002039 p53 binding(GO:0002039)
0.2 10.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 3.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 2.1 GO:0005042 netrin receptor activity(GO:0005042)
0.2 2.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 4.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 4.6 GO:0043236 laminin binding(GO:0043236)
0.2 3.5 GO:0030552 cAMP binding(GO:0030552)
0.2 4.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 2.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 6.3 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.2 4.1 GO:0031267 small GTPase binding(GO:0031267)
0.2 2.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 6.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 2.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 7.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 5.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 8.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 7.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 5.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.8 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 8.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.6 GO:0022829 wide pore channel activity(GO:0022829)
0.1 2.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 35.7 GO:0015631 tubulin binding(GO:0015631)
0.1 5.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 12.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 3.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 1.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 3.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 2.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 6.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 5.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 4.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.8 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 21.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 3.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.6 GO:0090079 translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.1 2.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.5 GO:0015248 sterol transporter activity(GO:0015248)
0.1 8.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 8.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.0 80.9 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 1.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 4.6 GO:0008201 heparin binding(GO:0008201)
0.0 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 12.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 4.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 5.6 GO:0005179 hormone activity(GO:0005179)
0.0 6.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 2.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 9.4 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 3.9 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.6 15.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 17.3 PID INSULIN PATHWAY Insulin Pathway
0.3 2.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 6.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 10.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 6.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 11.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 7.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 2.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 3.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
2.0 27.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.8 33.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.6 27.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.4 19.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
1.0 15.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.7 3.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.7 6.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.6 13.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 9.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 3.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 7.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 5.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 3.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 6.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 5.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 5.9 REACTOME KINESINS Genes involved in Kinesins
0.3 5.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 4.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 4.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 7.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 4.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 4.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 5.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System