PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
irf2a Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000007387	interferon regulatory factor 2a
irf2 Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000040465	interferon regulatory factor 2
irf1b Links NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000043249	interferon regulatory factor 1b

Gene	Promoter	Pearson corr. coef.	P-value	Plot
irf2	dr11_v1_chr14_-_4121052_4121052	0.86	1.2e-28	Click!
irf1b	dr11_v1_chr21_+_45627775_45627775	0.77	1.1e-19	Click!
irf2a	dr11_v1_chr1_+_39865748_39865753	-0.10	3.5e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_22675475 Show fit	59.33	ENSDART00000134423	ponzr3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plac8 onzin related protein 3
chr19_-_7115229 Show fit	54.45	ENSDART00000001930	psmb13a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit beta 13a
chr13_+_13681681 Show fit	48.09	ENSDART00000057825	cfd Links NCBI UniProt ZFIN ENSEMBL Google Show fit	complement factor D (adipsin)
chr19_+_7115223 Show fit	44.64	ENSDART00000001359	psmb12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit beta 12
chr13_+_22675802 Show fit	43.82	ENSDART00000145538 ENSDART00000143312	zgc:193505 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:193505
chr9_+_30387930 Show fit	40.34	ENSDART00000112827	si:dkey-18p12.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-18p12.4
chr10_-_22095505 Show fit	39.66	ENSDART00000140210	ponzr10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plac8 onzin related protein 10
chr9_-_45601103 Show fit	38.94	ENSDART00000180465	agr1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	anterior gradient 1
chr10_+_17776981 Show fit	37.07	ENSDART00000141693	ccl19b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 19b
chr16_+_23487051 Show fit	35.88	ENSDART00000145496	icn2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ictacalcin 2
chr16_+_29492937 Show fit	34.98	ENSDART00000011497	ctsk Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin K
chr3_+_34670076 Show fit	34.12	ENSDART00000133457	dlx4a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	distal-less homeobox 4a
chr22_-_5553007 Show fit	34.02	ENSDART00000165269	zgc:171601 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171601
chr12_-_4388704 Show fit	33.30	ENSDART00000152168	si:ch211-173d10.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-173d10.1
chr1_-_7930679 Show fit	33.14	ENSDART00000146090	si:dkey-79f11.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-79f11.10
chr19_+_1414604 Show fit	31.40	ENSDART00000159024	btr29 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 29
chr6_-_42983843 Show fit	31.07	ENSDART00000130666	tnfrsf18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor necrosis factor receptor superfamily, member 18
chr5_+_13373593 Show fit	30.47	ENSDART00000051668 ENSDART00000183883	ccl19a.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr7_+_22637515 Show fit	30.02	ENSDART00000158698	si:dkey-112a7.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-112a7.5
chr11_+_1584747 Show fit	28.86	ENSDART00000154583	si:dkey-40c23.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-40c23.2
chr13_-_34858500 Show fit	28.44	ENSDART00000184843	sptlc3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serine palmitoyltransferase, long chain base subunit 3
chr1_+_1805294 Show fit	28.28	ENSDART00000103850	atp1a1a.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr23_+_26142807 Show fit	27.29	ENSDART00000158878	ptpn22 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine phosphatase, non-receptor type 22
chr19_+_7124337 Show fit	26.68	ENSDART00000031380	tap2a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transporter associated with antigen processing, subunit type a
chr6_-_11091449 Show fit	26.60	ENSDART00000127209	pttg1ipa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	PTTG1 interacting protein a
chr4_-_17669881 Show fit	26.39	ENSDART00000066997	dram1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	DNA-damage regulated autophagy modulator 1
chr5_-_38170996 Show fit	25.55	ENSDART00000145805	si:ch211-284e13.12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-284e13.12
chr23_+_26142613 Show fit	25.46	ENSDART00000165046	ptpn22 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	protein tyrosine phosphatase, non-receptor type 22
chr11_-_20096018 Show fit	25.46	ENSDART00000030420	ogfrl2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	opioid growth factor receptor-like 2
chr24_+_12945803 Show fit	25.04	ENSDART00000005105	psme1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome activator subunit 1
chr5_-_38064065 Show fit	24.53	ENSDART00000137181	si:dkey-111e8.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-111e8.5
chr3_+_36424055 Show fit	24.51	ENSDART00000170318	si:ch1073-443f11.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-443f11.2
chr5_-_38063585 Show fit	24.41	ENSDART00000164947	si:dkey-111e8.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-111e8.5
chr15_-_47929455 Show fit	24.37	ENSDART00000064462	psma6l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit alpha 6, like
chr16_-_51271962 Show fit	23.68	ENSDART00000164021 ENSDART00000046420	serpinb1l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr23_+_642001 Show fit	23.59	ENSDART00000030643 ENSDART00000124850	irf10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 10
chr1_-_25177086 Show fit	23.44	ENSDART00000144711 ENSDART00000177225	tmem154 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 154
chr13_+_7387822 Show fit	23.19	ENSDART00000148240	exoc3l4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	exocyst complex component 3-like 4
chr4_-_26095755 Show fit	23.17	ENSDART00000100611 ENSDART00000191266	si:ch211-244b2.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-244b2.3
chr8_+_47099033 Show fit	23.15	ENSDART00000142979	arhgef16 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho guanine nucleotide exchange factor (GEF) 16
chr1_-_52431220 Show fit	23.02	ENSDART00000111256	zgc:194101 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194101
chr11_+_1608348 Show fit	22.90	ENSDART00000162438	si:dkey-40c23.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-40c23.3
chr4_-_12795030 Show fit	22.50	ENSDART00000150427	b2m Links NCBI UniProt ZFIN ENSEMBL Google Show fit	beta-2-microglobulin
chr8_-_36469117 Show fit	22.12	ENSDART00000111240	mhc2dab Links NCBI UniProt ZFIN ENSEMBL Google Show fit	major histocompatibility complex class II DAB gene
chr17_-_23631400 Show fit	22.09	ENSDART00000079563	fas Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Fas cell surface death receptor
chr11_+_1575435 Show fit	21.65	ENSDART00000155713 ENSDART00000156562	si:dkey-40c23.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-40c23.1
chr21_-_22673758 Show fit	21.62	ENSDART00000164910	gig2i Links NCBI UniProt ZFIN ENSEMBL Google Show fit	grass carp reovirus (GCRV)-induced gene 2i
chr18_-_38270077 Show fit	21.58	ENSDART00000185546	caprin1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cell cycle associated protein 1b
chr14_+_36889893 Show fit	21.55	ENSDART00000124159	si:ch211-132p1.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-132p1.3
chr3_+_29941777 Show fit	21.45	ENSDART00000113889	ifi35 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon-induced protein 35
chr4_-_26108053 Show fit	21.21	ENSDART00000066951	si:ch211-244b2.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-244b2.4
chr16_+_48753664 Show fit	20.87	ENSDART00000155148	si:ch73-31d8.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-31d8.2
chr18_-_38270596 Show fit	20.77	ENSDART00000098889	caprin1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cell cycle associated protein 1b
chr23_+_642395 Show fit	20.71	ENSDART00000186995	irf10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon regulatory factor 10
chr5_-_57723929 Show fit	20.66	ENSDART00000144237	gig2p Links NCBI UniProt ZFIN ENSEMBL Google Show fit	grass carp reovirus (GCRV)-induced gene 2p
chr22_+_29990448 Show fit	20.41	ENSDART00000165313	si:dkey-286j15.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-286j15.3
chr13_-_37615029 Show fit	20.22	ENSDART00000111199	si:dkey-188i13.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-188i13.6
chr3_-_22366562 Show fit	20.11	ENSDART00000129447	ifnphi1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon phi 1
chr25_+_4751879 Show fit	20.05	ENSDART00000169465	si:zfos-2372e4.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-2372e4.1
chr1_-_58002973 Show fit	19.97	ENSDART00000140390	si:ch211-114l13.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-114l13.9
chr23_-_5101847 Show fit	19.89	ENSDART00000122240	etv7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ets variant 7
chr19_-_15281996 Show fit	19.88	ENSDART00000103784	edn2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin 2
chr22_-_36926342 Show fit	19.87	ENSDART00000151804	si:dkey-37m8.11 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-37m8.11
chr23_-_37575030 Show fit	19.69	ENSDART00000031875	tor1l3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	torsin family 1 like 3
chr7_+_39416336 Show fit	19.32	ENSDART00000171783	CT030188.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr5_-_38197080 Show fit	19.14	ENSDART00000140708	si:ch211-284e13.9 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-284e13.9
chr19_+_23296616 Show fit	18.99	ENSDART00000134567	irgf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	immunity-related GTPase family, f1
chr1_-_8020589 Show fit	18.86	ENSDART00000143881	si:dkeyp-9d4.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-9d4.2
chr4_-_26107841 Show fit	18.86	ENSDART00000172012	si:ch211-244b2.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-244b2.4
chr4_+_5842433 Show fit	18.86	ENSDART00000124085 ENSDART00000179848	usp18 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin specific peptidase 18
chr19_+_7575141 Show fit	18.71	ENSDART00000051528	s100u Links NCBI UniProt ZFIN ENSEMBL Google Show fit	S100 calcium binding protein U
chr19_+_7575341 Show fit	18.61	ENSDART00000134271	s100u Links NCBI UniProt ZFIN ENSEMBL Google Show fit	S100 calcium binding protein U
chr2_-_42035250 Show fit	18.39	ENSDART00000056460 ENSDART00000140788	gbp1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	guanylate binding protein 1
chr12_+_17106117 Show fit	18.28	ENSDART00000149990	acta2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	actin, alpha 2, smooth muscle, aorta
chr18_+_17624295 Show fit	18.21	ENSDART00000151865 ENSDART00000190408 ENSDART00000189204 ENSDART00000188894 ENSDART00000033762 ENSDART00000193471	nlrc5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	NLR family, CARD domain containing 5
chr20_+_26916639 Show fit	18.08	ENSDART00000077787	serpinb1l2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 2
chr13_+_47810211 Show fit	17.94	ENSDART00000122964	zmp:0000001006 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zmp:0000001006
chr5_-_37116265 Show fit	17.93	ENSDART00000057613	il13ra2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 13 receptor, alpha 2
chr3_-_22366032 Show fit	17.86	ENSDART00000029849	ifnphi1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interferon phi 1
chr24_-_34680956 Show fit	17.85	ENSDART00000171009	ctnna1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	catenin (cadherin-associated protein), alpha 1
chr1_+_58332000 Show fit	17.82	ENSDART00000145234	ggt1l2.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	gamma-glutamyltransferase 1 like 2.1
chr7_+_31891110 Show fit	17.71	ENSDART00000173883	mybpc3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin binding protein C, cardiac
chr7_+_2259413 Show fit	17.51	ENSDART00000173420	si:dkey-187j14.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-187j14.7
chr22_+_36902352 Show fit	17.37	ENSDART00000036273	trim35-20 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	tripartite motif containing 35-20
chr16_-_22192006 Show fit	17.25	ENSDART00000163338	il6r Links NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 6 receptor
chr4_-_76383223 Show fit	17.20	ENSDART00000161866 ENSDART00000168456 ENSDART00000174287 ENSDART00000174048	zgc:123107 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:123107
chr23_+_46183410 Show fit	17.17	ENSDART00000167596 ENSDART00000151149 ENSDART00000150896	btr31 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 31
chr22_-_10580194 Show fit	17.16	ENSDART00000105848	SHISA4 (1 of many) Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-42i9.7
chr3_-_29941357 Show fit	17.10	ENSDART00000147732 ENSDART00000137973 ENSDART00000103523	grna Links NCBI UniProt ZFIN ENSEMBL Google Show fit	granulin a
chr17_+_25397070 Show fit	17.05	ENSDART00000164254	zgc:154055 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:154055
chr3_-_336299 Show fit	17.02	ENSDART00000105021	mhc1zfa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	major histocompatibility complex class I ZFA
chr5_+_38612134 Show fit	17.01	ENSDART00000135600 ENSDART00000181144	si:ch211-271e10.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-271e10.2
chr13_-_46200240 Show fit	16.90	ENSDART00000056984	ftr69 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 69
chr23_-_5783421 Show fit	16.87	ENSDART00000131521 ENSDART00000019455	csrp1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cysteine and glycine-rich protein 1a
chr16_-_50952266 Show fit	16.72	ENSDART00000165408	si:dkeyp-97a10.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-97a10.3
chr1_-_7951002 Show fit	16.57	ENSDART00000138187	si:dkey-79f11.8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-79f11.8
chr15_-_36347858 Show fit	16.34	ENSDART00000155274 ENSDART00000157936	si:dkey-23k10.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-23k10.2
chr23_-_44723102 Show fit	16.32	ENSDART00000129138	mogat3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	monoacylglycerol O-acyltransferase 3a
chr3_+_1724941 Show fit	16.17	ENSDART00000193402	BX321875.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr15_-_18209672 Show fit	16.16	ENSDART00000141508 ENSDART00000136280	btr16 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 16
chr12_-_30583668 Show fit	15.95	ENSDART00000153406	casp7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase 7, apoptosis-related cysteine peptidase
chr6_+_13045885 Show fit	15.90	ENSDART00000104757	casp8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase 8, apoptosis-related cysteine peptidase
chr18_-_38270430 Show fit	15.84	ENSDART00000139519	caprin1b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cell cycle associated protein 1b
chr18_+_30998472 Show fit	15.75	ENSDART00000154993 ENSDART00000099333	cd151l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CD151 antigen, like
chr10_+_5060191 Show fit	15.75	ENSDART00000145908 ENSDART00000122397	carm1l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	coactivator-associated arginine methyltransferase 1, like
chr3_+_24603923 Show fit	15.55	ENSDART00000172589	si:dkey-68o6.6 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-68o6.6
chr19_-_7144548 Show fit	15.52	ENSDART00000147177 ENSDART00000134850	psmb8a Links NCBI UniProt ZFIN ENSEMBL Google Show fit psmb13a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit beta 8A proteasome subunit beta 13a
chr8_-_13641022 Show fit	15.47	ENSDART00000080875	b3gnt3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr7_+_20344222 Show fit	15.37	ENSDART00000141186 ENSDART00000139274	ponzr1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plac8 onzin related protein 1
chr11_-_30341431 Show fit	15.33	ENSDART00000078378	cflara Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CASP8 and FADD-like apoptosis regulator a
chr21_-_7265219 Show fit	15.30	ENSDART00000158852	egfl7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	EGF-like-domain, multiple 7
chr7_+_3442834 Show fit	15.15	ENSDART00000138247	si:ch211-285c6.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-285c6.2
chr10_+_7585928 Show fit	15.01	ENSDART00000166686	tex15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	testis expressed 15
chr9_+_25330905 Show fit	14.93	ENSDART00000101470	itm2bb Links NCBI UniProt ZFIN ENSEMBL Google Show fit	integral membrane protein 2Bb
chr24_-_39858710 Show fit	14.72	ENSDART00000134251	slc12a7b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 12 (potassium/chloride transporter), member 7b
chr9_+_3153717 Show fit	14.65	ENSDART00000191958	si:zfos-979f1.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-979f1.2
chr4_-_76206413 Show fit	14.64	ENSDART00000170738	si:ch211-106j21.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-106j21.5
chr18_+_13248956 Show fit	14.63	ENSDART00000080709	plcg2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	phospholipase C, gamma 2
chr9_+_42269059 Show fit	14.62	ENSDART00000113435	si:dkey-10c21.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-10c21.1
chr16_-_9802449 Show fit	14.61	ENSDART00000081208	tapbpl Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TAP binding protein (tapasin)-like
chr7_+_20505311 Show fit	14.50	ENSDART00000187335	si:dkey-19b23.12 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-19b23.12
chr22_-_18164671 Show fit	14.35	ENSDART00000014057	rfxank Links NCBI UniProt ZFIN ENSEMBL Google Show fit	regulatory factor X-associated ankyrin-containing protein
chr21_-_33478164 Show fit	14.32	ENSDART00000191542	si:ch73-42p12.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-42p12.2
chr18_-_14860435 Show fit	14.28	ENSDART00000018502	mapk12a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	mitogen-activated protein kinase 12a
chr7_+_20344486 Show fit	14.26	ENSDART00000134004 ENSDART00000139685	ponzr1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	plac8 onzin related protein 1
chr25_-_31629095 Show fit	14.25	ENSDART00000170673 ENSDART00000166930	lamb1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	laminin, beta 1a
chr9_+_3153466 Show fit	14.21	ENSDART00000135619	si:zfos-979f1.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-979f1.2
chr7_-_19614916 Show fit	14.20	ENSDART00000169029	zgc:194655 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194655
chr22_+_5687615 Show fit	14.19	ENSDART00000133241 ENSDART00000019854 ENSDART00000138102	dnase1l4.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	deoxyribonuclease 1 like 4, tandem duplicate 2
chr22_-_6941098 Show fit	14.11	ENSDART00000105864	zgc:171500 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171500
chr11_+_27347076 Show fit	14.11	ENSDART00000173383	fbln2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	fibulin 2
chr23_-_42752550 Show fit	14.06	ENSDART00000187059	si:ch73-217n20.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-217n20.1
chr3_+_1942219 Show fit	14.02	ENSDART00000114520	zgc:165583 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:165583
chr7_-_8981507 Show fit	13.91	ENSDART00000161422	si:ch211-183d5.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-183d5.2
chr5_+_22406672 Show fit	13.85	ENSDART00000141385	si:dkey-27p18.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-27p18.3
chr3_+_24618012 Show fit	13.85	ENSDART00000111997	zgc:171506 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171506
chr20_-_34663209 Show fit	13.71	ENSDART00000132545	slc25a24 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_53508580 Show fit	13.70	ENSDART00000073978	zgc:171711 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171711
chr8_-_23240156 Show fit	13.69	ENSDART00000131632	ptk6a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	PTK6 protein tyrosine kinase 6a
chr3_-_32958505 Show fit	13.52	ENSDART00000147374 ENSDART00000136919	casp6l1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	caspase 6, apoptosis-related cysteine peptidase, like 1
chr15_-_41756454 Show fit	13.47	ENSDART00000139498 ENSDART00000099302	ftr72 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 72
chr2_-_37862380 Show fit	13.46	ENSDART00000186005	si:ch211-284o19.8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-284o19.8
chr5_-_30382925 Show fit	13.46	ENSDART00000125381	gig2o Links NCBI UniProt ZFIN ENSEMBL Google Show fit	grass carp reovirus (GCRV)-induced gene 2o
chr3_-_32611833 Show fit	13.39	ENSDART00000151282	si:ch73-248e21.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-248e21.5
chr4_-_77216726 Show fit	13.18	ENSDART00000099943	psmb10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	proteasome subunit beta 10
chr2_+_45479841 Show fit	13.18	ENSDART00000151856	si:ch211-66k16.28 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-66k16.28
chr20_-_1439256 Show fit	13.18	ENSDART00000002928	themis Links NCBI UniProt ZFIN ENSEMBL Google Show fit	thymocyte selection associated
chr22_-_18164835 Show fit	13.10	ENSDART00000143189	rfxank Links NCBI UniProt ZFIN ENSEMBL Google Show fit	regulatory factor X-associated ankyrin-containing protein
chr5_+_38619813 Show fit	13.09	ENSDART00000133314	si:ch211-271e10.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-271e10.3
chr4_-_76079075 Show fit	13.02	ENSDART00000158469	si:ch211-232d10.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-232d10.3
chr11_+_37638873 Show fit	12.97	ENSDART00000186384 ENSDART00000184291 ENSDART00000131782 ENSDART00000140502	sh2d5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	SH2 domain containing 5
chr10_+_35358675 Show fit	12.89	ENSDART00000193263	si:dkey-259j3.5 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-259j3.5
chr23_+_43177290 Show fit	12.87	ENSDART00000193300 ENSDART00000186065	si:dkey-65j6.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-65j6.2
chr7_+_19482084 Show fit	12.78	ENSDART00000173873	si:ch211-212k18.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k18.7
chr3_-_16142057 Show fit	12.77	ENSDART00000016616	arl5c Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ADP-ribosylation factor-like 5C
chr5_+_4338874 Show fit	12.64	ENSDART00000141866	sat1a.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr22_+_19290199 Show fit	12.60	ENSDART00000148173	si:dkey-21e2.15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-21e2.15
chr22_+_31023205 Show fit	12.58	ENSDART00000111561	zmp:0000000735 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zmp:0000000735
chr5_+_40835601 Show fit	12.57	ENSDART00000147767	si:dkey-3h3.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-3h3.3
chr12_+_20641471 Show fit	12.56	ENSDART00000133654	calcoco2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium binding and coiled-coil domain 2
chr22_+_19289970 Show fit	12.51	ENSDART00000137976 ENSDART00000132386	si:dkey-21e2.15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-21e2.15
chr21_-_43428040 Show fit	12.50	ENSDART00000148325	stk26 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	serine/threonine protein kinase 26
chr25_+_245018 Show fit	12.48	ENSDART00000155344	zgc:92481 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92481
chr5_+_38684651 Show fit	12.45	ENSDART00000137852	si:dkey-58f10.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-58f10.10
chr23_+_5524247 Show fit	12.35	ENSDART00000189679 ENSDART00000083622	tead3a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TEA domain family member 3 a
chr15_+_32268790 Show fit	12.33	ENSDART00000154457	fhdc4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	FH2 domain containing 4
chr24_+_38216340 Show fit	12.26	ENSDART00000188561	CU896602.4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr5_-_38820046 Show fit	12.23	ENSDART00000182886	cnot6l Links NCBI UniProt ZFIN ENSEMBL Google Show fit	CCR4-NOT transcription complex, subunit 6-like
chr10_+_8885769 Show fit	12.19	ENSDART00000139466	itga2.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr8_-_30204650 Show fit	12.16	ENSDART00000133209	zgc:162939 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162939
chr22_-_17459587 Show fit	12.12	ENSDART00000142267	si:ch211-197g15.10 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-197g15.10
chr12_-_37299646 Show fit	12.05	ENSDART00000146142 ENSDART00000085201	pmp22b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	peripheral myelin protein 22b
chr2_-_8611675 Show fit	12.03	ENSDART00000138223	si:ch211-71m22.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-71m22.1
chr1_-_57839070 Show fit	12.02	ENSDART00000152571	si:dkey-1c7.3 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-1c7.3
chr18_+_26422124 Show fit	11.99	ENSDART00000060245	ctsh Links NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin H
chr22_+_6254194 Show fit	11.94	ENSDART00000112388 ENSDART00000135176	rnasel4 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ribonuclease like 4
chr21_+_8533533 Show fit	11.88	ENSDART00000077924	FO834888.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr1_-_8141135 Show fit	11.87	ENSDART00000152295	FAM83G Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-9d4.4
chr3_-_24093144 Show fit	11.85	ENSDART00000103982	nfe2l1a Links NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear factor, erythroid 2-like 1a
chr6_+_52947699 Show fit	11.84	ENSDART00000180913	uba7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin-like modifier activating enzyme 7
chr12_+_17154655 Show fit	11.83	ENSDART00000028003	ankrd22 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ankyrin repeat domain 22
chr22_-_5518117 Show fit	11.81	ENSDART00000164613	CABZ01064972.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit
chr4_+_7822773 Show fit	11.63	ENSDART00000171391	si:ch1073-67j19.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-67j19.2
chr15_-_41734639 Show fit	11.62	ENSDART00000154230 ENSDART00000167443	ftr90 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 90
chr13_-_42306348 Show fit	11.55	ENSDART00000003706	kmo Links NCBI UniProt ZFIN ENSEMBL Google Show fit	kynurenine 3-monooxygenase
chr14_+_12169979 Show fit	11.54	ENSDART00000129953	rhogd Links NCBI UniProt ZFIN ENSEMBL Google Show fit	ras homolog gene family, member Gd
chr8_-_27687095 Show fit	11.50	ENSDART00000086946	mov10b.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Moloney leukemia virus 10b, tandem duplicate 1
chr3_-_48980319 Show fit	11.44	ENSDART00000165319	ftr42 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 42
chr9_+_18023288 Show fit	11.42	ENSDART00000098355	tnfsf11 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	TNF superfamily member 11
chr8_+_25629722 Show fit	11.42	ENSDART00000026807	wasa Links NCBI UniProt ZFIN ENSEMBL Google Show fit	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr15_-_20180475 Show fit	11.40	ENSDART00000048183	exoc3l2b Links NCBI UniProt ZFIN ENSEMBL Google Show fit	exocyst complex component 3-like 2b
chr7_+_19483277 Show fit	11.39	ENSDART00000173750	si:ch211-212k18.7 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k18.7
chr7_+_19615056 Show fit	11.39	ENSDART00000124752 ENSDART00000190297	si:ch211-212k18.15 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-212k18.15
chr15_-_29162193 Show fit	11.38	ENSDART00000138449 ENSDART00000099885	xaf1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	XIAP associated factor 1
chr15_-_18197008 Show fit	11.37	ENSDART00000147632	si:ch211-247l8.8 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-247l8.8
chr23_-_42752387 Show fit	11.36	ENSDART00000149781	si:ch73-217n20.1 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-217n20.1
chr4_+_60482963 Show fit	11.30	ENSDART00000157679	si:dkey-211i20.2 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-211i20.2
chr19_+_4066449 Show fit	11.23	ENSDART00000162461	btr26 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	bloodthirsty-related gene family, member 26
chr6_+_36839509 Show fit	11.12	ENSDART00000190605 ENSDART00000104160	zgc:110788 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110788
chr23_+_16864130 Show fit	11.11	ENSDART00000060181	zgc:114174 Links NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:114174

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.0	48.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
6.1	18.3	GO:0090131	mesenchyme migration(GO:0090131)
5.5	22.1	GO:0070227	lymphocyte apoptotic process(GO:0070227)
5.3	15.9	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
5.2	52.2	GO:1900407	regulation of cellular response to oxidative stress(GO:1900407)
5.0	19.9	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
4.7	38.0	GO:0046685	response to arsenic-containing substance(GO:0046685)
4.5	142.7	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
4.4	13.2	GO:0043383	negative T cell selection(GO:0043383)
4.3	43.0	GO:0051601	exocyst localization(GO:0051601)
3.9	19.7	GO:0071763	nuclear membrane organization(GO:0071763)
3.7	14.9	GO:0042985	negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
3.5	17.7	GO:0003210	cardiac atrium formation(GO:0003210)
3.3	26.2	GO:0031179	peptide modification(GO:0031179)
3.2	12.8	GO:1903292	protein localization to Golgi membrane(GO:1903292)
3.2	12.6	GO:0006598	polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
3.1	40.7	GO:0045824	negative regulation of innate immune response(GO:0045824)
3.0	9.0	GO:0018872	arsonoacetate metabolic process(GO:0018872)
2.9	17.2	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
2.7	13.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
2.7	29.6	GO:0072088	renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
2.7	8.0	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
2.6	7.9	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
2.6	28.4	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
2.4	14.3	GO:0055016	hypochord development(GO:0055016)
2.3	16.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
2.3	11.5	GO:0043420	anthranilate metabolic process(GO:0043420)
2.3	11.5	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
2.1	17.1	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.0	9.8	GO:0035739	negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.9	7.7	GO:0045903	positive regulation of translational fidelity(GO:0045903)
1.8	7.3	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
1.7	7.0	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
1.7	8.7	GO:0010693	regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
1.6	42.5	GO:0019882	antigen processing and presentation(GO:0019882)
1.5	6.0	GO:0048313	organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
1.5	10.5	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
1.5	28.3	GO:0071436	cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
1.4	7.0	GO:0098535	de novo centriole assembly(GO:0098535)
1.4	15.3	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.3	54.4	GO:0071346	cellular response to interferon-gamma(GO:0071346)
1.3	5.2	GO:0090161	Golgi ribbon formation(GO:0090161)
1.3	3.9	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
1.3	8.8	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.2	22.7	GO:0046686	response to cadmium ion(GO:0046686)
1.2	15.0	GO:0007140	male meiosis(GO:0007140)
1.1	5.6	GO:0019374	galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
1.1	4.3	GO:2000392	lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
1.1	4.3	GO:0006526	arginine biosynthetic process(GO:0006526)
1.0	3.0	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
1.0	16.9	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.9	14.2	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.9	10.2	GO:0018120	peptidyl-arginine ADP-ribosylation(GO:0018120)
0.8	12.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.8	4.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.8	18.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.8	11.4	GO:2000601	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.8	9.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.7	2.9	GO:0070291	N-acylethanolamine metabolic process(GO:0070291)
0.7	4.3	GO:0019563	glycerol catabolic process(GO:0019563)
0.7	31.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.7	9.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.7	17.0	GO:0010507	negative regulation of autophagy(GO:0010507)
0.6	14.7	GO:0055075	potassium ion homeostasis(GO:0055075)
0.6	2.9	GO:0014005	microglia development(GO:0014005)
0.6	16.7	GO:0070593	dendrite self-avoidance(GO:0070593)
0.6	41.8	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.6	58.7	GO:0017148	negative regulation of translation(GO:0017148)
0.5	12.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.5	4.2	GO:0043363	nucleate erythrocyte differentiation(GO:0043363)
0.5	46.4	GO:0009612	response to mechanical stimulus(GO:0009612)
0.5	25.6	GO:0034599	cellular response to oxidative stress(GO:0034599)
0.5	8.7	GO:0097194	execution phase of apoptosis(GO:0097194)
0.5	2.0	GO:0061045	negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.5	25.4	GO:0010952	positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.5	11.2	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.5	2.5	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.5	27.2	GO:0045785	positive regulation of cell adhesion(GO:0045785)
0.4	12.4	GO:0035329	hippo signaling(GO:0035329)
0.4	11.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.4	2.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.4	1.3	GO:0005997	xylulose metabolic process(GO:0005997)
0.4	8.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.4	2.4	GO:0089700	protein kinase D signaling(GO:0089700)
0.4	14.6	GO:0009395	phospholipid catabolic process(GO:0009395)
0.4	8.5	GO:0031638	zymogen activation(GO:0031638)
0.4	45.8	GO:0017038	protein import(GO:0017038)
0.4	3.4	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.4	36.9	GO:0031101	fin regeneration(GO:0031101)
0.4	7.8	GO:0006825	copper ion transport(GO:0006825)
0.4	10.2	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.4	1.4	GO:0060220	blood vessel maturation(GO:0001955) retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3	3.1	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3	17.0	GO:0048821	erythrocyte development(GO:0048821)
0.3	2.0	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3	18.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.3	11.1	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.3	3.2	GO:0006108	malate metabolic process(GO:0006108)
0.3	10.9	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.3	1.7	GO:0070285	pigment cell development(GO:0070285)
0.3	4.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.3	8.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.3	1.7	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.3	34.7	GO:0021782	glial cell development(GO:0021782)
0.3	3.3	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.3	6.0	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.3	4.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3	3.5	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.2	30.7	GO:0042742	defense response to bacterium(GO:0042742)
0.2	0.7	GO:0044036	cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.2	16.9	GO:0007254	JNK cascade(GO:0007254)
0.2	12.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.2	11.4	GO:1901800	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2	1.4	GO:0032728	interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.2	28.3	GO:0090630	activation of GTPase activity(GO:0090630)
0.2	1.1	GO:0006999	nuclear pore organization(GO:0006999)
0.2	0.9	GO:1901490	regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.2	15.3	GO:0001570	vasculogenesis(GO:0001570)
0.2	2.8	GO:0043248	proteasome assembly(GO:0043248) chaperone-mediated protein complex assembly(GO:0051131)
0.2	0.8	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2	2.5	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.2	1.3	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791) medium-chain fatty acid catabolic process(GO:0051793)
0.2	5.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	3.6	GO:0034453	microtubule anchoring(GO:0034453)
0.2	6.5	GO:0032456	endocytic recycling(GO:0032456)
0.1	4.0	GO:0008272	sulfate transport(GO:0008272)
0.1	94.7	GO:0016567	protein ubiquitination(GO:0016567)
0.1	0.8	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centriole replication(GO:0046600) negative regulation of centrosome cycle(GO:0046606) negative regulation of organelle assembly(GO:1902116)
0.1	2.7	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1	9.3	GO:0001894	tissue homeostasis(GO:0001894)
0.1	7.1	GO:0007338	single fertilization(GO:0007338) fertilization(GO:0009566)
0.1	1.1	GO:0031272	pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1	7.9	GO:0007492	endoderm development(GO:0007492)
0.1	0.2	GO:0036503	ERAD pathway(GO:0036503)
0.1	3.2	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.1	10.2	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	8.6	GO:0006401	RNA catabolic process(GO:0006401)
0.1	27.9	GO:0000122	negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.1	1.9	GO:0031936	negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.1	1.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.1	0.7	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	13.7	GO:0042157	lipoprotein metabolic process(GO:0042157)
0.1	6.8	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	21.2	GO:0019941	modification-dependent protein catabolic process(GO:0019941) modification-dependent macromolecule catabolic process(GO:0043632)
0.1	2.8	GO:0032543	mitochondrial translation(GO:0032543)
0.1	1.1	GO:0051642	centrosome localization(GO:0051642)
0.1	3.2	GO:0008643	carbohydrate transport(GO:0008643)
0.1	6.8	GO:0002040	sprouting angiogenesis(GO:0002040)
0.1	0.5	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	2.4	GO:0051603	proteolysis involved in cellular protein catabolic process(GO:0051603)
0.1	0.5	GO:0032098	regulation of appetite(GO:0032098)
0.1	2.3	GO:0030901	midbrain development(GO:0030901)
0.1	28.2	GO:1902680	positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.0	7.2	GO:0061053	somite development(GO:0061053)
0.0	0.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	7.1	GO:0042127	regulation of cell proliferation(GO:0042127)
0.0	5.6	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	6.3	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.0	2.6	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	4.0	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.0	3.7	GO:0006457	protein folding(GO:0006457)
0.0	84.4	GO:0035556	intracellular signal transduction(GO:0035556)
0.0	1.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	2.1	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.0	0.1	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0	1.5	GO:0048884	neuromast development(GO:0048884)
0.0	0.4	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	1.6	GO:0007030	Golgi organization(GO:0007030)
0.0	16.7	GO:0002376	immune system process(GO:0002376)
0.0	2.7	GO:0006631	fatty acid metabolic process(GO:0006631)
0.0	1.7	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.3	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.3	25.0	GO:0008537	proteasome activator complex(GO:0008537)
5.1	142.7	GO:0005839	proteasome core complex(GO:0005839)
4.9	39.3	GO:0042613	MHC class II protein complex(GO:0042613)
4.2	25.5	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
2.9	8.6	GO:0005775	vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
2.8	28.4	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.5	7.7	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
1.4	38.3	GO:0000145	exocyst(GO:0000145)
1.3	5.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.3	6.3	GO:0097433	dense body(GO:0097433)
1.2	6.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
1.1	18.3	GO:0005869	dynactin complex(GO:0005869)
1.0	4.1	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.0	4.8	GO:1990071	TRAPPII protein complex(GO:1990071)
0.9	17.8	GO:0030057	desmosome(GO:0030057)
0.9	4.6	GO:0097224	sperm connecting piece(GO:0097224)
0.9	4.3	GO:0032433	filopodium tip(GO:0032433)
0.6	14.3	GO:0005605	basal lamina(GO:0005605) laminin complex(GO:0043256)
0.6	4.3	GO:0005663	DNA replication factor C complex(GO:0005663)
0.6	4.3	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5	12.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.5	23.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.5	24.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.4	123.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.4	3.7	GO:0016272	prefoldin complex(GO:0016272)
0.3	11.5	GO:0043186	P granule(GO:0043186)
0.3	2.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.3	16.8	GO:0031901	early endosome membrane(GO:0031901)
0.3	86.9	GO:0005764	lysosome(GO:0005764)
0.3	2.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.3	1.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.3	12.8	GO:0031984	trans-Golgi network(GO:0005802) organelle subcompartment(GO:0031984) Golgi subcompartment(GO:0098791)
0.3	12.2	GO:0008305	integrin complex(GO:0008305)
0.2	27.7	GO:0005783	endoplasmic reticulum(GO:0005783)
0.2	3.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.2	58.9	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.2	1.5	GO:0016586	RSC complex(GO:0016586)
0.2	13.0	GO:0060076	postsynaptic density(GO:0014069) excitatory synapse(GO:0060076)
0.2	205.6	GO:0005615	extracellular space(GO:0005615)
0.2	0.5	GO:1902737	dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2	2.6	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	4.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	33.1	GO:0005938	cell cortex(GO:0005938)
0.1	2.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.1	7.9	GO:0022626	cytosolic ribosome(GO:0022626)
0.1	5.2	GO:0005776	autophagosome(GO:0005776)
0.1	15.3	GO:0009986	cell surface(GO:0009986)
0.1	9.6	GO:0030018	Z disc(GO:0030018)
0.1	1.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.1	7.8	GO:0005884	actin filament(GO:0005884)
0.1	0.3	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	1.1	GO:0000815	ESCRT III complex(GO:0000815)
0.1	6.1	GO:0005795	Golgi stack(GO:0005795)
0.1	0.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	72.6	GO:0005829	cytosol(GO:0005829)
0.1	3.0	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.1	3.0	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	12.7	GO:0005667	transcription factor complex(GO:0005667)
0.0	9.0	GO:0000785	chromatin(GO:0000785)
0.0	1.9	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0032806	cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.7	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	66.6	GO:0016021	integral component of membrane(GO:0016021)
0.0	6.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
12.7	38.0	GO:0005132	type I interferon receptor binding(GO:0005132)
10.6	53.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
10.6	52.8	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
6.8	20.3	GO:0015462	protein-transmembrane transporting ATPase activity(GO:0015462)
6.2	118.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
5.0	19.9	GO:0031708	endothelin B receptor binding(GO:0031708)
4.2	25.0	GO:0061133	endopeptidase activator activity(GO:0061133)
4.1	28.4	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.8	11.5	GO:0032574	5'-3' RNA helicase activity(GO:0032574)
3.2	47.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
3.2	22.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
3.0	9.0	GO:0030792	arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
2.9	26.2	GO:0036374	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
2.9	8.6	GO:0033897	ribonuclease T2 activity(GO:0033897)
2.8	28.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
2.4	65.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
2.3	15.8	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
2.2	6.6	GO:0031956	medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
2.0	6.0	GO:1902945	metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
1.8	93.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
1.8	12.6	GO:0019809	spermidine binding(GO:0019809)
1.7	8.6	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
1.7	6.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.6	16.3	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
1.6	17.7	GO:0032036	myosin heavy chain binding(GO:0032036)
1.6	61.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
1.6	9.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
1.5	4.6	GO:0032027	myosin light chain binding(GO:0032027)
1.5	10.5	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.4	14.2	GO:0004530	deoxyribonuclease I activity(GO:0004530)
1.4	5.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3	3.9	GO:0009041	uridylate kinase activity(GO:0009041)
1.3	6.3	GO:0098973	structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.2	19.7	GO:0031386	protein tag(GO:0031386)
1.2	54.4	GO:0048020	CCR chemokine receptor binding(GO:0048020)
1.2	6.0	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
1.2	4.7	GO:0031005	filamin binding(GO:0031005)
1.2	11.5	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
1.1	4.3	GO:0016842	amidine-lyase activity(GO:0016842)
1.1	10.8	GO:0051373	telethonin binding(GO:0031433) FATZ binding(GO:0051373)
1.0	10.3	GO:0050700	CARD domain binding(GO:0050700)
1.0	4.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.0	12.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.0	9.8	GO:0016936	galactoside binding(GO:0016936)
1.0	8.8	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.9	19.7	GO:0019894	kinesin binding(GO:0019894)
0.9	2.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.8	8.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.8	12.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.6	17.9	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	17.1	GO:0042805	actinin binding(GO:0042805)
0.6	2.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.6	9.8	GO:0033613	activating transcription factor binding(GO:0033613)
0.6	17.0	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.6	7.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.6	14.7	GO:0015377	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.5	2.0	GO:0008488	gamma-glutamyl carboxylase activity(GO:0008488)
0.5	16.7	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.5	69.1	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.5	3.4	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5	7.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5	3.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.5	5.9	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.4	15.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.4	11.5	GO:0004698	protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.4	2.5	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.4	7.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	3.9	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.4	4.3	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4	1.5	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.4	13.1	GO:0004707	MAP kinase activity(GO:0004707)
0.4	5.8	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	5.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	17.8	GO:0008013	beta-catenin binding(GO:0008013)
0.3	74.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.3	35.2	GO:0019955	cytokine binding(GO:0019955)
0.3	11.0	GO:0004629	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.3	2.9	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3	4.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.3	1.1	GO:0004649	poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.3	4.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.3	3.5	GO:0005163	nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3	8.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.3	1.8	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3	13.7	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.3	6.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	29.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	0.8	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	3.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	5.5	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	26.2	GO:0043492	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.2	4.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2	177.6	GO:0008270	zinc ion binding(GO:0008270)
0.2	8.9	GO:0005178	integrin binding(GO:0005178)
0.2	97.2	GO:0005525	GTP binding(GO:0005525)
0.2	12.6	GO:0004540	ribonuclease activity(GO:0004540)
0.1	1.1	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.1	7.7	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.1	0.7	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	4.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	20.8	GO:0000149	SNARE binding(GO:0000149)
0.1	24.8	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	1.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1	2.1	GO:0033691	sialic acid binding(GO:0033691)
0.1	18.0	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	1.5	GO:0030165	PDZ domain binding(GO:0030165)
0.1	3.5	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1	2.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	1.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	0.3	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.1	5.2	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	2.8	GO:0019843	rRNA binding(GO:0019843)
0.0	5.4	GO:0004175	endopeptidase activity(GO:0004175)
0.0	5.6	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	4.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	2.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	8.5	GO:0016829	lyase activity(GO:0016829)
0.0	1.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	3.5	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	3.1	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.7	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	5.3	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	5.2	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	1.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	2.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	7.8	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.3	GO:0070628	proteasome binding(GO:0070628)
0.0	9.0	GO:0008289	lipid binding(GO:0008289)
0.0	2.6	GO:0005125	cytokine activity(GO:0005125)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0003688	DNA replication origin binding(GO:0003688)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.7	38.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
2.2	17.9	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
2.2	17.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.7	53.6	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
1.0	16.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.9	19.9	PID ENDOTHELIN PATHWAY	Endothelins
0.7	23.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.7	17.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.6	11.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	11.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.4	8.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.4	7.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.4	1.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.3	18.3	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	27.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	6.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.2	3.5	PID SHP2 PATHWAY	SHP2 signaling
0.2	5.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	5.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	10.1	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	4.3	PID ATR PATHWAY	ATR signaling pathway
0.1	8.3	PID E2F PATHWAY	E2F transcription factor network
0.1	3.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	7.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	2.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	12.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.7	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	2.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.7	38.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
4.5	22.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
4.4	56.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
3.5	42.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
2.6	75.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
2.5	17.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
2.4	24.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
2.3	16.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.6	9.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
1.5	44.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.5	17.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.8	18.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.7	9.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.7	27.4	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.6	15.5	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.5	4.9	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.5	3.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5	14.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.5	5.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.4	10.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.4	4.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.4	17.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	15.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.3	10.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.3	4.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.3	4.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	12.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	2.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	0.4	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2	12.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.2	3.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	3.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	7.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	3.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	2.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.8	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	1.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG