Project
PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
Navigation
Downloads
Results for hoxc13b+hoxd13a
Z-value: 1.18
Motif logo
Transcription factors associated with hoxc13b+hoxd13a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hoxc13b | dr11_v1_chr11_+_2156430_2156430 | -0.59 | 5.8e-10 | Click! |
| hoxd13a | dr11_v1_chr9_-_1990323_1990323 | 0.18 | 8.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_22637515 Show fit | 14.19 |
ENSDART00000158698
|
si:dkey-112a7.5 |
|
| chr22_-_24297510 Show fit | 13.22 |
ENSDART00000163297
|
si:ch211-117l17.6 |
|
| chr12_+_13256415 Show fit | 12.55 |
ENSDART00000144542
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like |
|
| chr17_-_8886735 Show fit | 12.36 |
ENSDART00000121997
|
NK-lysin tandem duplicate 3 |
|
| chr17_+_2549503 Show fit | 12.14 |
ENSDART00000156843
|
si:dkey-248g15.3 |
|
| chr20_+_26683933 Show fit | 11.53 |
ENSDART00000139852
ENSDART00000077751 |
forkhead box Q1b |
|
| chr17_+_42274825 Show fit | 11.02 |
ENSDART00000020156
|
paired box 1a |
|
| chr1_+_54650048 Show fit | 10.59 |
ENSDART00000141207
|
si:ch211-202h22.7 |
|
| chr9_-_33081978 Show fit | 10.33 |
ENSDART00000100918
|
zgc:172053 |
|
| chr3_-_43872889 Show fit | 10.08 |
ENSDART00000170553
|
mesothelin a |
Network of associatons between targets according to the STRING database.
First level regulatory network of hoxc13b+hoxd13a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 16.1 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.2 | 14.2 | GO:0046939 | nucleotide phosphorylation(GO:0046939) |
| 3.2 | 9.6 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 1.9 | 9.3 | GO:0097510 | base-excision repair, AP site formation via deaminated base removal(GO:0097510) |
| 0.1 | 9.3 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.1 | 8.7 | GO:0051216 | cartilage development(GO:0051216) |
| 2.9 | 8.6 | GO:0071236 | cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237) |
| 0.1 | 8.6 | GO:0001666 | response to hypoxia(GO:0001666) |
| 0.1 | 8.5 | GO:0001503 | ossification(GO:0001503) |
| 2.1 | 8.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 26.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 15.3 | GO:0009986 | cell surface(GO:0009986) |
| 0.2 | 15.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 12.7 | GO:0000323 | lytic vacuole(GO:0000323) |
| 0.5 | 12.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 11.5 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.3 | 11.0 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 8.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.9 | 7.9 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.2 | 7.5 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.5 | GO:0038023 | signaling receptor activity(GO:0038023) |
| 0.1 | 18.2 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 16.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.7 | 12.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.2 | 10.9 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 10.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 9.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 3.1 | 9.3 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.1 | 9.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 2.1 | 8.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 15.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 8.1 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.2 | 5.7 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.2 | 4.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 4.2 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.1 | 4.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 2.9 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.2 | 2.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.8 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 13.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.4 | 11.4 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 8.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.8 | 8.1 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 1.2 | 7.2 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 6.5 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.2 | 4.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.3 | 4.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 3.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 3.3 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |