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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hdx

Z-value: 0.65

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Transcription factors associated with hdx

Gene Symbol Gene ID Gene Info
hdx
ENSDARG00000079382 highly divergent homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hdxdr11_v1_chr14_-_6225336_6225336-0.413.8e-05Click!

Activity profile of hdx motif

Sorted Z-values of hdx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_6742287 5.82 ENSDART00000140752
miox
myo-inositol oxygenase
chr1_+_24382651 5.52 ENSDART00000123789
qdprb2
quinoid dihydropteridine reductase b2
chr13_-_9895564 5.29 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr23_-_12788113 4.89 ENSDART00000103231
ENSDART00000146640
ENSDART00000180549
si:dkey-96f10.1
si:dkey-96f10.1
chr4_+_1530287 4.50 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr8_-_33568964 4.05 ENSDART00000138921
mvb12bb
multivesicular body subunit 12Bb
chr7_-_24022340 3.95 ENSDART00000149133
cideb
cell death-inducing DFFA-like effector b
chr23_+_5108374 3.75 ENSDART00000114263
zgc:194242
zgc:194242
chr22_-_278328 3.25 ENSDART00000098072
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr3_-_3413669 3.24 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
zgc:171446
chr14_-_25599002 2.93 ENSDART00000040955
slc25a48
solute carrier family 25, member 48
chr25_+_10811551 2.87 ENSDART00000167730
anpepb
alanyl (membrane) aminopeptidase b
chr14_-_30390145 2.78 ENSDART00000045423
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr17_-_2596125 2.74 ENSDART00000175740
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr13_+_33688474 2.61 ENSDART00000161465
CABZ01087953.1

chr20_-_25542183 2.42 ENSDART00000024350
cyp2ad2
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr4_-_8040436 2.32 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr9_-_12888082 2.26 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr2_-_51634431 2.22 ENSDART00000165568
pigr
polymeric immunoglobulin receptor
chr7_+_20031202 2.09 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr15_-_6946286 2.05 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr5_+_10046643 1.93 ENSDART00000137543
ENSDART00000186917
gstt2
glutathione S-transferase theta 2
chr18_-_25276932 1.93 ENSDART00000076183
plin1
perilipin 1
chr17_-_2834764 1.90 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr2_+_31600661 1.80 ENSDART00000139039
si:ch211-106h4.4
si:ch211-106h4.4
chr8_+_8468139 1.70 ENSDART00000186684
comta
catechol-O-methyltransferase a
chr18_+_9810642 1.64 ENSDART00000143965
CACNA2D1
si:dkey-266j7.2
chr23_+_36106790 1.62 ENSDART00000128533
hoxc3a
homeobox C3a
chr5_-_3885727 1.55 ENSDART00000143250
mlxipl
MLX interacting protein like
chr23_+_19655301 1.54 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr17_+_15433518 1.48 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr7_+_20030888 1.47 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr17_-_6536305 1.44 ENSDART00000154855
cenpo
centromere protein O
chr17_-_6618574 1.43 ENSDART00000184486
si:ch211-189e2.3
si:ch211-189e2.3
chr14_-_30490465 1.41 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr6_-_2133737 1.41 ENSDART00000158535
vstm2l
V-set and transmembrane domain containing 2 like
chr11_+_44503774 1.41 ENSDART00000169295
ero1b
endoplasmic reticulum oxidoreductase beta
chr16_-_33930060 1.37 ENSDART00000110743
ENSDART00000101898
dnali1
dynein, axonemal, light intermediate chain 1
chr22_-_23267893 1.37 ENSDART00000105613
si:dkey-121a9.3
si:dkey-121a9.3
chr23_-_31633201 1.37 ENSDART00000143335
ENSDART00000053531
slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr22_+_28995391 1.33 ENSDART00000164486
pimr99
Pim proto-oncogene, serine/threonine kinase, related 99
chr19_-_20270178 1.32 ENSDART00000144891
ENSDART00000090883
gpnmb
glycoprotein (transmembrane) nmb
chr19_+_41173386 1.30 ENSDART00000142773
asb4
ankyrin repeat and SOCS box containing 4
chr7_+_58699718 1.29 ENSDART00000049264
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr17_-_6641535 1.28 ENSDART00000154540
ENSDART00000180384
si:ch211-189e2.3
si:ch211-189e2.3
chr23_+_36122058 1.28 ENSDART00000184448
hoxc3a
homeobox C3a
chr25_-_23583101 1.28 ENSDART00000149107
ENSDART00000103704
ENSDART00000184903
nap1l4a
nucleosome assembly protein 1-like 4a
chr14_-_30490763 1.26 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
micu3b
mitochondrial calcium uptake family, member 3b
chr11_+_6116503 1.26 ENSDART00000176170
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr21_-_39931285 1.25 ENSDART00000180010
ENSDART00000024407
tmigd1
transmembrane and immunoglobulin domain containing 1
chr19_-_24555935 1.25 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr19_-_2420990 1.24 ENSDART00000181498
TMEM196 (1 of many)
transmembrane protein 196
chr17_-_29192987 1.24 ENSDART00000164302
sptbn5
spectrin, beta, non-erythrocytic 5
chr14_+_26719691 1.23 ENSDART00000078522
ENSDART00000172927
eef1g
eukaryotic translation elongation factor 1 gamma
chr3_+_3099492 1.23 ENSDART00000154156
si:dkey-30g5.1
si:dkey-30g5.1
chr4_+_34599955 1.19 ENSDART00000150790
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr9_-_23152092 1.19 ENSDART00000180155
ENSDART00000186935
lypd6b
LY6/PLAUR domain containing 6B
chr13_-_35459928 1.17 ENSDART00000144109
slx4ip
SLX4 interacting protein
chr22_+_1615691 1.16 ENSDART00000171555
si:ch211-255f4.13
si:ch211-255f4.13
chr21_-_2322102 1.14 ENSDART00000162867
zgc:66483
zgc:66483
chr3_+_16724614 1.14 ENSDART00000182135
gys1
glycogen synthase 1 (muscle)
chr15_+_31428332 1.10 ENSDART00000141429
or103-5
odorant receptor, family C, subfamily 103, member 5
chr17_+_48164536 1.10 ENSDART00000161750
ENSDART00000156923
plekhd1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr21_+_21679086 1.09 ENSDART00000146225
or125-5
odorant receptor, family E, subfamily 125, member 5
chr10_-_4980150 1.09 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr17_-_40110782 1.08 ENSDART00000126929
si:dkey-187k19.2
si:dkey-187k19.2
chr3_-_40945710 1.08 ENSDART00000138719
ENSDART00000102416
cyp3c4
cytochrome P450, family 3, subfamily C, polypeptide 4
chr8_-_48675152 1.07 ENSDART00000164544
pimr183
Pim proto-oncogene, serine/threonine kinase, related 183
chr2_-_24488652 1.07 ENSDART00000052067
insl3
insulin-like 3 (Leydig cell)
chr17_-_6536466 1.07 ENSDART00000188735
cenpo
centromere protein O
chr18_-_17077596 1.06 ENSDART00000111821
il17c
interleukin 17c
chr23_-_44226556 1.06 ENSDART00000149115
zgc:158659
zgc:158659
chr8_+_7033049 1.05 ENSDART00000064172
ENSDART00000134440
gpd1a
glycerol-3-phosphate dehydrogenase 1a
chr8_+_999421 1.04 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr15_-_18232712 1.02 ENSDART00000081199
wu:fj20b03
wu:fj20b03
chr16_-_19026414 0.98 ENSDART00000141208
pimr98
Pim proto-oncogene, serine/threonine kinase, related 98
chr8_-_48675411 0.98 ENSDART00000165081
pimr183
Pim proto-oncogene, serine/threonine kinase, related 183
chr20_+_14789148 0.98 ENSDART00000164761
tmed5
transmembrane p24 trafficking protein 5
chr22_+_29027037 0.97 ENSDART00000170071
pimr97
Pim proto-oncogene, serine/threonine kinase, related 97
chr6_+_21005725 0.97 ENSDART00000041370
cx44.2
connexin 44.2
chr3_+_25154078 0.96 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr8_-_53044089 0.96 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr5_-_4245186 0.96 ENSDART00000145912
si:ch211-283g2.3
si:ch211-283g2.3
chr14_+_34495216 0.95 ENSDART00000147756
wnt8a
wingless-type MMTV integration site family, member 8a
chr25_-_18778356 0.95 ENSDART00000111425
fbxl13
F-box and leucine-rich repeat protein 13
chr11_-_29737088 0.94 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr2_-_40890004 0.93 ENSDART00000191746
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr23_+_37579107 0.92 ENSDART00000169376
plekhg5b
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr20_+_6543674 0.92 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr17_+_6536152 0.92 ENSDART00000062952
ENSDART00000121789
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr22_-_5171362 0.90 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr10_-_36721726 0.90 ENSDART00000122132
pimr137
Pim proto-oncogene, serine/threonine kinase, related 137
chr4_-_64141714 0.89 ENSDART00000128628
BX914205.3

chr8_+_17884569 0.88 ENSDART00000134660
slc44a5b
solute carrier family 44, member 5b
chr25_+_19710619 0.87 ENSDART00000156435
mxg
myxovirus (influenza virus) resistance G
chr10_-_25570647 0.86 ENSDART00000134215
grik1a
glutamate receptor, ionotropic, kainate 1a
chr6_-_9459440 0.86 ENSDART00000064991
pimr71
Pim proto-oncogene, serine/threonine kinase, related 71
chr15_+_25683069 0.85 ENSDART00000148190
hic1
hypermethylated in cancer 1
chr7_+_22399669 0.84 ENSDART00000144375
fgf11a
fibroblast growth factor 11a
chr8_-_53044300 0.84 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr19_-_18626952 0.83 ENSDART00000168004
ENSDART00000162034
ENSDART00000165486
ENSDART00000167971
rps18
ribosomal protein S18
chr6_-_24143923 0.83 ENSDART00000157948
si:ch73-389b16.1
si:ch73-389b16.1
chr5_+_27267186 0.82 ENSDART00000182238
ENSDART00000087857
unc5db
unc-5 netrin receptor Db
chr22_-_4944795 0.81 ENSDART00000147116
pku300
pku300
chr20_+_10727022 0.81 ENSDART00000104185
si:ch211-182e10.4
si:ch211-182e10.4
chr16_+_26735894 0.80 ENSDART00000191605
ENSDART00000185175
rad54b
RAD54 homolog B (S. cerevisiae)
chr4_+_70556298 0.80 ENSDART00000170985
si:dkey-11d20.1
si:dkey-11d20.1
chr6_+_72040 0.80 ENSDART00000122957
crygm4
crystallin, gamma M4
chr18_+_41820039 0.79 ENSDART00000128345
pgr
progesterone receptor
chr25_-_15268443 0.79 ENSDART00000151827
ccdc73
coiled-coil domain containing 73
chr6_+_16982613 0.79 ENSDART00000156104
pimr8
Pim proto-oncogene, serine/threonine kinase, related 8
chr15_-_30989360 0.79 ENSDART00000155265
lgals9l6
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 6
chr5_-_30620625 0.78 ENSDART00000098273
tcnl
transcobalamin like
chr16_+_38820486 0.78 ENSDART00000131866
trhra
thyrotropin-releasing hormone receptor a
chr15_-_22304193 0.78 ENSDART00000115158
zgc:194114
zgc:194114
chr5_+_62356304 0.76 ENSDART00000148381
aspa
aspartoacylase
chr4_-_43070566 0.76 ENSDART00000183779
si:dkey-54j5.2
si:dkey-54j5.2
chr25_+_29160102 0.74 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr4_-_51692811 0.74 ENSDART00000159625
si:dkeyp-90h9.1
si:dkeyp-90h9.1
chr3_+_43955864 0.74 ENSDART00000168267
BX571715.1

chr9_-_5318873 0.73 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr12_+_13118540 0.73 ENSDART00000077840
ENSDART00000127870
cmn
calymmin
chr8_-_13428740 0.72 ENSDART00000131826
CR354547.3

chr1_-_11519934 0.72 ENSDART00000162060
sdk1b
sidekick cell adhesion molecule 1b
chr23_+_17437554 0.72 ENSDART00000184282
BX649300.3

chr4_-_10958074 0.72 ENSDART00000150478
si:ch211-161n3.4
si:ch211-161n3.4
chr25_+_36333993 0.71 ENSDART00000184379
CR354435.2

chr16_-_26820634 0.71 ENSDART00000111156
pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr16_-_54471235 0.71 ENSDART00000061572
cyp11c1
cytochrome P450, family 11, subfamily C, polypeptide 1
chr4_-_10599062 0.71 ENSDART00000048003
tspan12
tetraspanin 12
chr21_-_28439596 0.71 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr18_+_15706160 0.71 ENSDART00000131524
si:ch211-264e16.1
si:ch211-264e16.1
chr10_-_18492617 0.70 ENSDART00000179936
ENSDART00000193799
ENSDART00000193198
si:dkey-28o19.1
si:dkey-28o19.1
chr11_-_25775447 0.70 ENSDART00000161301
plch2b
phospholipase C, eta 2b
chr3_-_33029938 0.69 ENSDART00000181730
CT583642.1

chr24_+_9881219 0.69 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr9_-_43073960 0.69 ENSDART00000059460
ttn.2
titin, tandem duplicate 2
chr4_+_2269815 0.69 ENSDART00000075788
si:ch73-89b15.3
si:ch73-89b15.3
chr23_+_43870886 0.68 ENSDART00000102658
ENSDART00000149088
nfxl1
nuclear transcription factor, X-box binding-like 1
chr1_+_8579197 0.68 ENSDART00000186329
AL928650.4

chr2_-_36494308 0.67 ENSDART00000110378
BX901889.2

chr2_+_45696743 0.67 ENSDART00000114225
ENSDART00000169279
CU467828.1

chr10_+_21722892 0.66 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr9_+_25840720 0.66 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr2_-_40890264 0.66 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr7_-_29223614 0.66 ENSDART00000173598
herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr19_-_43657468 0.65 ENSDART00000150940
si:ch211-193k19.2
si:ch211-193k19.2
chr2_-_36497113 0.65 ENSDART00000109291
BX901889.4

chr4_-_16706776 0.64 ENSDART00000079461
dennd5b
DENN/MADD domain containing 5B
chr1_-_28950366 0.64 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr13_-_48295723 0.64 ENSDART00000115137
KCNK12
potassium two pore domain channel subfamily K member 12
chr8_+_12975963 0.64 ENSDART00000132821
ENSDART00000181755
ENSDART00000185061
ENSDART00000193727
dram2a
DNA-damage regulated autophagy modulator 2a
chr17_-_6535941 0.64 ENSDART00000109249
cenpo
centromere protein O
chr22_-_4784658 0.64 ENSDART00000140839
CU570881.1

chr11_+_6752468 0.64 ENSDART00000187046
ENSDART00000182089
pde4cb
phosphodiesterase 4C, cAMP-specific b
chr24_-_27409599 0.63 ENSDART00000041770
ccl34b.3
chemokine (C-C motif) ligand 34b, duplicate 3
chr6_-_16868834 0.62 ENSDART00000156503
pimr41
Pim proto-oncogene, serine/threonine kinase, related 41
chr8_-_48770163 0.61 ENSDART00000160959
pimr184
Pim proto-oncogene, serine/threonine kinase, related 184
chr2_-_40196547 0.59 ENSDART00000168098
ccl34a.3
chemokine (C-C motif) ligand 34a, duplicate 3
chr13_+_40686133 0.59 ENSDART00000146112
hps1
Hermansky-Pudlak syndrome 1
chr21_+_17051478 0.59 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr25_+_22587306 0.58 ENSDART00000067479
stra6
stimulated by retinoic acid 6
chr16_+_4181105 0.57 ENSDART00000180921
yrdc
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr5_-_37247654 0.56 ENSDART00000112312
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr4_+_391297 0.56 ENSDART00000030215
rpl18a
ribosomal protein L18a
chr11_+_5565082 0.55 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
si:ch73-40i7.5
chr20_-_25644131 0.55 ENSDART00000138997
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr18_-_17077419 0.54 ENSDART00000148714
il17c
interleukin 17c
chr14_+_15620640 0.54 ENSDART00000188867
si:dkey-203a12.9
si:dkey-203a12.9
chr14_+_46287296 0.53 ENSDART00000183620
cabp2b
calcium binding protein 2b
chr7_-_19614916 0.53 ENSDART00000169029
zgc:194655
zgc:194655
chr4_-_16706941 0.52 ENSDART00000033053
ENSDART00000140510
ENSDART00000141119
dennd5b
DENN/MADD domain containing 5B
chr9_-_12886108 0.52 ENSDART00000177283
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr17_+_6535694 0.51 ENSDART00000191681
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr4_-_29753895 0.51 ENSDART00000150742
si:dkey-191j3.1
si:dkey-191j3.1
chr9_+_8364553 0.50 ENSDART00000190713
si:dkey-90l23.2
si:dkey-90l23.2
chr4_+_7508316 0.50 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr11_+_30295582 0.50 ENSDART00000122424
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr7_+_49865049 0.50 ENSDART00000164165
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr12_+_30788912 0.50 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr21_-_32684570 0.49 ENSDART00000162873
adamts2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr23_+_37815645 0.49 ENSDART00000011627
irx7
iroquois homeobox 7
chr25_+_3564220 0.49 ENSDART00000170005
zgc:194202
zgc:194202
chr7_-_1148539 0.48 ENSDART00000173447
si:dkey-31g16.2
si:dkey-31g16.2
chr9_+_22080122 0.48 ENSDART00000065956
ENSDART00000136014
crygm2e
crystallin, gamma M2e
chr7_+_19615056 0.47 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr18_-_7112882 0.47 ENSDART00000176292
si:dkey-88e18.8
si:dkey-88e18.8
chr2_+_25378457 0.46 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr6_+_49082796 0.46 ENSDART00000182446
tshba
thyroid stimulating hormone, beta subunit, a
chr13_+_38213694 0.46 ENSDART00000057320
zgc:171579
zgc:171579
chr3_+_5504990 0.45 ENSDART00000143626
si:ch73-264i18.2
si:ch73-264i18.2
chr7_+_17353030 0.45 ENSDART00000098020
si:busm1-169i8.11
si:busm1-169i8.11
chr4_-_71108793 0.45 ENSDART00000189856
si:dkeyp-80d11.1
si:dkeyp-80d11.1
chr1_-_29761086 0.44 ENSDART00000136760
alg11
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr7_-_17268111 0.44 ENSDART00000169319
nitr10a
novel immune-type receptor 10a
chr25_-_21609645 0.43 ENSDART00000087817
DOCK4 (1 of many)
si:dkey-81e3.1
chr20_-_26841544 0.43 ENSDART00000088875
mylk4b
myosin light chain kinase family, member 4b
chr18_+_814328 0.42 ENSDART00000157801
ENSDART00000188492
ENSDART00000184489
fam219b
family with sequence similarity 219, member B
chr14_+_12316581 0.42 ENSDART00000170115
ENSDART00000149757
si:ch211-125c23.3
cx31.7
si:ch211-125c23.3
connexin 31.7
chr10_+_39164638 0.40 ENSDART00000188997
CU633908.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hdx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
1.0 4.0 GO:1902592 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.7 2.9 GO:0006844 acyl carnitine transport(GO:0006844)
0.6 5.5 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.5 2.8 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.4 5.8 GO:0006020 inositol metabolic process(GO:0006020)
0.4 1.4 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 0.9 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.3 0.8 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.3 1.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 4.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.7 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.2 1.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.7 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.2 1.4 GO:0046323 glucose import(GO:0046323)
0.2 2.7 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.8 GO:0032689 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 1.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.6 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.8 GO:0030728 ovulation(GO:0030728)
0.1 2.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 4.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 3.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.0 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.7 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.3 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 1.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 2.4 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.7 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 3.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0001757 somite specification(GO:0001757)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 1.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 1.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 8.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 2.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.2 GO:0042493 response to drug(GO:0042493)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.8 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 3.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.8 3.1 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.3 0.9 GO:0097189 apoptotic body(GO:0097189)
0.2 3.9 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.7 GO:1990246 uniplex complex(GO:1990246)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.5 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.6 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0030428 cell septum(GO:0030428)
0.1 0.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 3.2 GO:0005811 lipid particle(GO:0005811)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.4 GO:0030175 filopodium(GO:0030175)
0.0 1.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.9 3.7 GO:0008169 C-methyltransferase activity(GO:0008169)
0.7 2.9 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.5 5.8 GO:0008199 ferric iron binding(GO:0008199)
0.4 1.7 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 5.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 2.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 1.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 2.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 4.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 1.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.3 1.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 2.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 2.5 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.4 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.8 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 3.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.1 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.7 GO:0004100 chitin synthase activity(GO:0004100)
0.1 0.6 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.8 GO:0016936 galactoside binding(GO:0016936)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 4.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.5 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 3.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.8 REACTOME TRANSLATION Genes involved in Translation
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation