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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxp1a+foxp1b+foxp3a_foxg1b_foxp2_foxd1+foxd7_foxo1a+foxo1b

Z-value: 2.80

Motif logo

Transcription factors associated with foxp1a+foxp1b+foxp3a_foxg1b_foxp2_foxd1+foxd7_foxo1a+foxo1b

Gene Symbol Gene ID Gene Info
ENSDARG00000004843 forkhead box P1a
ENSDARG00000014181 forkhead box P1b
ENSDARG00000055750 forkhead box P3a
ENSDARG00000032705 forkhead box G1b
ENSDARG00000005453 forkhead box P2
ENSDARG00000029179 forkhead box D1
ENSDARG00000079699 zgc
ENSDARG00000061549 forkhead box O1 b
ENSDARG00000099555 forkhead box O1 a

Activity-expression correlation:

Activity profile of foxp1a+foxp1b+foxp3a_foxg1b_foxp2_foxd1+foxd7_foxo1a+foxo1b motif

Sorted Z-values of foxp1a+foxp1b+foxp3a_foxg1b_foxp2_foxd1+foxd7_foxo1a+foxo1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_48460239 56.13 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr19_+_10396042 46.95 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr14_-_26177156 45.57 ENSDART00000014149
FAT atypical cadherin 2
chr3_-_21280373 38.74 ENSDART00000003939
synaptogyrin 1a
chr14_-_36378494 38.59 ENSDART00000058503
glycoprotein M6Aa
chr14_-_7885707 36.02 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr20_+_27393668 35.73 ENSDART00000005473
transmembrane protein 179
chr23_-_19953089 35.43 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr12_+_25640480 33.85 ENSDART00000105608
protein kinase C, epsilon a
chr16_-_43025885 33.52 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr2_-_38125657 32.73 ENSDART00000143433
cerebellin 12
chr21_-_29100110 31.11 ENSDART00000142598
T cell immunoglobulin and mucin domain containing 4
chr6_+_36942966 31.08 ENSDART00000028895
neuronal growth regulator 1
chr17_-_6738538 30.86 ENSDART00000157125
visinin-like 1b
chr2_-_8017579 29.54 ENSDART00000040209
eph receptor B3a
chr14_-_34044369 28.72 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr25_-_19433244 28.18 ENSDART00000154778
microtubule-associated protein 1Ab
chr19_-_5103313 27.73 ENSDART00000037007
triosephosphate isomerase 1a
chr6_-_32999646 26.89 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr15_-_33933790 25.81 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
myelin associated glycoprotein
chr25_-_15049694 25.78 ENSDART00000162485
ENSDART00000164384
ENSDART00000165632
ENSDART00000159490
paired box 6a
chr23_-_29502287 25.63 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr1_+_53954230 24.72 ENSDART00000037729
ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr21_-_25522906 24.70 ENSDART00000110923
connector enhancer of kinase suppressor of Ras 2b
chr6_-_40744720 24.70 ENSDART00000154916
ENSDART00000186922
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_-_40397752 24.62 ENSDART00000178483

chr20_-_19590378 24.50 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr21_+_11684830 24.42 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr1_-_44901163 23.96 ENSDART00000145354
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3a
chr12_+_31729075 23.78 ENSDART00000152973
si:dkey-49c17.3
chr13_+_1100197 23.64 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr21_+_5209716 23.48 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr23_+_16620801 23.37 ENSDART00000189859
ENSDART00000184578
syntaphilin b
chr4_+_8168514 23.28 ENSDART00000150830
ninjurin 2
chr11_+_25112269 23.17 ENSDART00000147546
ndrg family member 3a
chr22_+_27090136 23.02 ENSDART00000136770
si:dkey-246e1.3
chr10_+_33895315 23.01 ENSDART00000142881
furry homolog b (Drosophila)
chr7_+_30787903 23.00 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr1_+_16127825 22.83 ENSDART00000122503
tumor suppressor candidate 3
chr6_+_21095918 22.56 ENSDART00000167225
SPEG complex locus a
chr6_+_38427570 22.56 ENSDART00000170612
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr21_+_5209476 22.28 ENSDART00000146400
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr24_-_4973765 22.22 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr9_+_52492639 21.65 ENSDART00000078939
membrane-associated ring finger (C3HC4) 4
chr15_+_18130109 21.49 ENSDART00000078723
DIX domain containing 1a
chr15_+_32249062 21.24 ENSDART00000133867
ENSDART00000152545
ENSDART00000082315
ENSDART00000152513
ENSDART00000152139
ADP-ribosylation factor interacting protein 2a
chr3_-_51912019 20.66 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr21_-_42097736 20.63 ENSDART00000100000
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr18_-_22094102 20.58 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr17_-_26911852 20.19 ENSDART00000045842
regulator of calcineurin 3
chr21_+_11685009 20.14 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr19_-_5103141 20.06 ENSDART00000150952
triosephosphate isomerase 1a
chr2_+_26240631 20.03 ENSDART00000129895
paralemmin 1b
chr23_-_29505463 19.96 ENSDART00000050915
kinesin family member 1B
chr18_+_17428506 19.66 ENSDART00000100223
zgc:91860
chr11_-_3552067 19.65 ENSDART00000163656
si:dkey-33m11.6
chr7_+_36898850 19.59 ENSDART00000113342
TOX high mobility group box family member 3
chr5_-_23317477 19.50 ENSDART00000090171
neuroligin 3b
chr1_+_25801648 19.29 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr20_+_30445971 19.18 ENSDART00000153150
myelin transcription factor 1-like, a
chr3_+_32403758 19.12 ENSDART00000156982
si:ch211-195b15.8
chr12_-_4781801 19.08 ENSDART00000167490
ENSDART00000121718
microtubule-associated protein tau a
chr11_-_8126223 18.47 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr11_+_6819050 17.99 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr5_-_40190949 17.75 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr15_-_18574716 17.73 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr7_-_38612230 17.35 ENSDART00000173678
C1q and TNF related 4
chr24_-_6678640 17.11 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr13_-_11378355 17.09 ENSDART00000164566
v-akt murine thymoma viral oncogene homolog 3a
chr3_-_28258462 17.09 ENSDART00000191573
RNA binding fox-1 homolog 1
chr15_+_8043751 16.91 ENSDART00000193701
cell adhesion molecule 2b
chr7_-_35710263 16.83 ENSDART00000043857
iroquois homeobox 5a
chr5_+_52625975 16.77 ENSDART00000170341
ENSDART00000168317
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr5_-_20879527 16.65 ENSDART00000134697
phosphoinositide-3-kinase interacting protein 1
chr7_-_58098814 16.56 ENSDART00000147287
ENSDART00000043984
ankyrin 2b, neuronal
chr23_-_36449111 16.09 ENSDART00000110478
zgc:174906
chr12_-_7607114 16.08 ENSDART00000158095
solute carrier family 16, member 9b
chr11_+_11120532 15.92 ENSDART00000026135
ENSDART00000189872
lymphocyte antigen 75
chr4_-_14207471 15.91 ENSDART00000015134
twinfilin actin-binding protein 1b
chr19_-_7358184 15.90 ENSDART00000092379
oxidation resistance 1b
chr3_-_60142530 15.79 ENSDART00000153247
si:ch211-120g10.1
chr13_+_22280983 15.64 ENSDART00000173258
ENSDART00000173379
ubiquitin specific peptidase 54a
chr21_-_41305748 15.54 ENSDART00000170457
neuronal vesicle trafficking associated 2
chr14_-_48939560 15.53 ENSDART00000021736
short coiled-coil protein b
chr7_-_33023404 15.29 ENSDART00000052383
CD81 molecule a
chr20_-_16849306 15.28 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr12_+_28367557 15.26 ENSDART00000066294
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr11_-_24191928 15.25 ENSDART00000136827
SRY (sex determining region Y)-box 12
chr14_-_4273396 15.00 ENSDART00000127318
FERM and PDZ domain containing 1b
chr9_-_3149896 14.93 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr18_-_1228688 14.66 ENSDART00000064403
neuroplastin b
chr14_+_9421510 14.58 ENSDART00000123652
high mobility group nucleosome binding domain 6
chr21_+_17301790 14.58 ENSDART00000145057
TSC complex subunit 1b
chr12_+_22404108 14.43 ENSDART00000153055
high density lipoprotein binding protein b
chr2_+_22795494 14.40 ENSDART00000042255
RAB6B, member RAS oncogene family b
chr13_-_25842074 14.36 ENSDART00000015154
poly(A) polymerase gamma
chr8_-_18262149 13.95 ENSDART00000143000
ring finger protein 220b
chr7_+_28724919 13.90 ENSDART00000011324
coiled-coil domain containing 102A
chr3_-_26191960 13.71 ENSDART00000113843
yippee-like 3
chr2_-_12243213 13.61 ENSDART00000113081
G protein-coupled receptor 158b
chr6_-_41138854 13.58 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr7_-_37555208 13.52 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr24_-_6647275 13.33 ENSDART00000161494
Rho GTPase activating protein 21a
chr24_-_21498802 13.20 ENSDART00000181235
ENSDART00000153695
ATPase phospholipid transporting 8A2
chr9_+_17348745 13.19 ENSDART00000147488
SLAIN motif family, member 1a
chr13_-_12006007 13.09 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr7_-_31941670 13.03 ENSDART00000180929
ENSDART00000075389
brain-derived neurotrophic factor
chr1_+_51312752 13.02 ENSDART00000063938
microtubule associated serine/threonine kinase 1a
chr20_-_34801181 12.95 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr6_-_30658755 12.83 ENSDART00000065215
ENSDART00000181302
leucine rich adaptor protein 1
chr13_-_12005429 12.64 ENSDART00000180302
meningioma expressed antigen 5 (hyaluronidase)
chr2_-_24462277 12.55 ENSDART00000033922
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr14_-_21219659 12.53 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr7_-_30082931 12.53 ENSDART00000075600
tetraspanin 3b
chr9_+_41459759 12.45 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr7_-_31618166 12.44 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr24_+_19210001 12.40 ENSDART00000179373
ENSDART00000139299
zgc:162928
chr9_+_33154841 12.21 ENSDART00000132465
dopey family member 2
chr11_-_29563437 12.18 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr21_+_25071805 12.16 ENSDART00000078651
DIX domain containing 1b
chr7_+_69470142 12.16 ENSDART00000073861
GABA(A) receptor-associated protein b
chr13_+_28612313 12.07 ENSDART00000077383
BLOC-1 related complex subunit 7
chr11_+_7580079 12.03 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr12_+_31729498 12.02 ENSDART00000188546
ENSDART00000182562
ENSDART00000186147
si:dkey-49c17.3
chr5_+_61799629 11.99 ENSDART00000113508
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr20_+_22666548 11.87 ENSDART00000147520
ligand of numb-protein X 1
chr3_-_13147310 11.86 ENSDART00000160840
protein kinase, cAMP-dependent, regulatory, type I, beta
chr2_+_26240339 11.84 ENSDART00000191006
paralemmin 1b
chr10_+_22890791 11.76 ENSDART00000176011
arrestin, beta 2a
chr7_+_69470442 11.73 ENSDART00000189593
GABA(A) receptor-associated protein b
chr3_+_32933663 11.70 ENSDART00000112742
neighbor of brca1 gene 1b
chr5_-_66749535 11.68 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr2_-_5942115 11.58 ENSDART00000154489
transmembrane protein 125b
chr17_-_14966384 11.48 ENSDART00000105064
thioredoxin domain containing 16
chr18_-_5781922 11.45 ENSDART00000128722
si:ch73-167i17.6
chr10_+_22891126 11.45 ENSDART00000057291
arrestin, beta 2a
chr9_+_38163876 11.42 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr14_-_14746051 11.36 ENSDART00000163199
ENSDART00000170623
ENSDART00000158629
ENSDART00000171581
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr18_-_13121983 11.32 ENSDART00000092648
ribitol xylosyltransferase 1
chr25_-_25434479 11.32 ENSDART00000171589
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr14_+_17197132 11.26 ENSDART00000054598
reticulon 4 receptor-like 2b
chr4_-_5764255 11.23 ENSDART00000113864
failed axon connections homolog a
chr6_+_38427357 11.17 ENSDART00000148678
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr23_-_27608257 11.10 ENSDART00000026314
PHD finger protein 8
chr22_-_21046654 10.99 ENSDART00000064902
single stranded DNA binding protein 4
chr8_+_23639124 10.99 ENSDART00000083108
5'-nucleotidase domain containing 2
chr17_+_18117029 10.98 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr3_-_13146631 10.98 ENSDART00000172460
protein kinase, cAMP-dependent, regulatory, type I, beta
chr7_-_24828296 10.96 ENSDART00000138193
OTU deubiquitinase, ubiquitin aldehyde binding 1b
chr25_+_3677650 10.79 ENSDART00000154348
prion protein, related sequence 3
chr20_+_10166297 10.77 ENSDART00000141877
potassium channel, subfamily K, member 10a
chr1_+_34763539 10.76 ENSDART00000077725
ENSDART00000113808
zgc:172122
chr10_-_32890617 10.74 ENSDART00000134922
potassium channel tetramerization domain containing 7
chr20_+_40457599 10.70 ENSDART00000017553
serine incorporator 1
chr6_-_21616659 10.67 ENSDART00000074256
protein phosphatase 1, regulatory subunit 12C
chr25_+_388258 10.66 ENSDART00000166834
regulatory factor X7b
chr18_-_14941840 10.60 ENSDART00000091729
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_+_38278860 10.56 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr22_-_25033105 10.52 ENSDART00000124220
neuronal pentraxin receptor b
chr16_-_21047872 10.47 ENSDART00000131582
chromobox homolog 3b
chr3_+_33340939 10.39 ENSDART00000128786
peptide YYa
chr11_+_18873619 10.35 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_+_26044969 10.29 ENSDART00000133523
HMG box domain containing 4a
chr1_-_8917902 10.28 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr14_+_49382180 10.25 ENSDART00000158329
TNFAIP3 interacting protein 1
chr14_-_17599452 10.23 ENSDART00000080042
RAB33A, member RAS oncogene family
chr16_-_28856112 10.21 ENSDART00000078543
synaptotagmin XIb
chr5_-_25236340 10.19 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_40994259 10.17 ENSDART00000101562
adrenoceptor alpha 2C
chr11_+_16153207 10.16 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr12_+_32729470 10.16 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr25_+_13731542 10.09 ENSDART00000161012
coiled-coil domain containing 135
chr15_-_33896159 10.08 ENSDART00000159791
myelin associated glycoprotein
chr15_+_26933196 10.02 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr23_-_30787932 9.99 ENSDART00000135771
myelin transcription factor 1a
chr23_+_30730121 9.98 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr10_+_7182423 9.98 ENSDART00000186788
pleckstrin and Sec7 domain containing 3, like
chr17_-_35881841 9.85 ENSDART00000110040
SRY (sex determining region Y)-box 11a
chr13_+_25428677 9.82 ENSDART00000186284
si:dkey-51a16.9
chr22_-_20011476 9.81 ENSDART00000093312
ENSDART00000093310
cugbp, Elav-like family member 5a
chr13_-_32906265 9.80 ENSDART00000113823
ENSDART00000171114
ENSDART00000180035
ENSDART00000137570
si:dkey-18j18.3
chr10_+_25982212 9.77 ENSDART00000128292
ENSDART00000108808
Fras1 related extracellular matrix protein 2a
chr10_+_7182168 9.76 ENSDART00000172766
pleckstrin and Sec7 domain containing 3, like
chr3_+_52999962 9.70 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr19_+_2275019 9.66 ENSDART00000136138
integrin, beta 8
chr19_-_10395683 9.58 ENSDART00000109488
zgc:194578
chr22_-_4760187 9.57 ENSDART00000081969
RAD23 homolog A, nucleotide excision repair protein b
chr5_+_23622177 9.54 ENSDART00000121504
connexin 27.5
chr5_+_37504309 9.54 ENSDART00000165465
si:ch1073-224n8.1
chr22_-_3449282 9.48 ENSDART00000136798
protein tyrosine phosphatase, receptor type, s, a
chr16_+_22654481 9.41 ENSDART00000179762
cholinergic receptor, nicotinic, beta 2b
chr3_+_34821327 9.39 ENSDART00000055262
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr9_-_44295071 9.34 ENSDART00000011837
neuronal differentiation 1
chr7_+_56472585 9.34 ENSDART00000135259
ENSDART00000073596
increased sodium tolerance 1 homolog (yeast)
chr12_-_2522487 9.28 ENSDART00000022471
ENSDART00000145213
mitogen-activated protein kinase 8b
chr2_-_42173834 9.17 ENSDART00000098357
ENSDART00000144707
solute carrier family 39 (zinc transporter), member 6
chr4_-_12007404 9.17 ENSDART00000092250
BTB (POZ) domain containing 11a
chr17_+_38295847 9.16 ENSDART00000008532
MAP3K12 binding inhibitory protein 1
chr8_-_30779101 9.16 ENSDART00000062229
purinergic receptor P2X, ligand-gated ion channel, 7
chr16_+_17389116 9.15 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb

Network of associatons between targets according to the STRING database.

First level regulatory network of foxp1a+foxp1b+foxp3a_foxg1b_foxp2_foxd1+foxd7_foxo1a+foxo1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
17.9 53.8 GO:0048917 posterior lateral line ganglion development(GO:0048917)
11.9 47.8 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
6.0 18.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
5.8 23.2 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
5.6 16.7 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
4.8 33.8 GO:0060221 retinal rod cell differentiation(GO:0060221)
4.8 19.3 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
4.7 23.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
4.3 30.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
4.1 20.6 GO:0070208 protein heterotrimerization(GO:0070208)
4.1 28.8 GO:0021534 cell proliferation in hindbrain(GO:0021534)
4.1 16.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
3.7 11.1 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
3.6 21.7 GO:0035881 amacrine cell differentiation(GO:0035881)
3.5 10.5 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
3.4 20.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
3.3 16.6 GO:0036371 protein localization to T-tubule(GO:0036371)
3.3 29.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
3.2 15.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
3.0 44.6 GO:0016486 peptide hormone processing(GO:0016486)
2.9 8.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
2.7 8.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
2.7 5.3 GO:0070528 protein kinase C signaling(GO:0070528)
2.6 15.4 GO:1990108 protein linear deubiquitination(GO:1990108)
2.4 36.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
2.4 9.5 GO:1901827 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
2.3 31.8 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
2.3 6.8 GO:0000423 macromitophagy(GO:0000423)
2.2 6.7 GO:0042245 RNA repair(GO:0042245)
2.2 15.5 GO:0061635 regulation of protein complex stability(GO:0061635)
2.2 10.8 GO:0021731 trigeminal motor nucleus development(GO:0021731)
2.1 6.4 GO:0071514 genetic imprinting(GO:0071514)
2.0 10.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
2.0 5.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.9 5.7 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
1.9 43.6 GO:0006491 N-glycan processing(GO:0006491)
1.9 30.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.9 16.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
1.8 11.0 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
1.8 7.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
1.8 19.5 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
1.7 5.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
1.6 16.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.6 9.7 GO:0003232 bulbus arteriosus development(GO:0003232)
1.6 4.8 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
1.6 4.7 GO:0071896 protein localization to adherens junction(GO:0071896)
1.6 29.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.5 9.0 GO:0016572 histone phosphorylation(GO:0016572)
1.5 22.2 GO:0001964 startle response(GO:0001964)
1.4 5.7 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
1.4 7.0 GO:2001223 negative regulation of neuron migration(GO:2001223)
1.4 19.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.3 22.8 GO:0015693 magnesium ion transport(GO:0015693)
1.3 4.0 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
1.3 9.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
1.3 6.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
1.3 61.2 GO:0021854 hypothalamus development(GO:0021854)
1.2 2.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
1.2 8.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
1.2 8.3 GO:0003404 optic vesicle morphogenesis(GO:0003404)
1.2 3.5 GO:0001779 natural killer cell differentiation(GO:0001779)
1.2 12.9 GO:0046548 retinal rod cell development(GO:0046548)
1.2 12.8 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
1.2 5.8 GO:0044805 late nucleophagy(GO:0044805)
1.2 5.8 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
1.1 5.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.1 3.4 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
1.1 39.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
1.1 4.5 GO:0035522 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.1 9.0 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
1.1 4.5 GO:0061549 sympathetic ganglion development(GO:0061549)
1.1 2.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.1 4.4 GO:0010259 multicellular organism aging(GO:0010259)
1.1 11.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
1.1 28.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
1.1 3.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
1.1 4.3 GO:0009098 leucine biosynthetic process(GO:0009098)
1.1 6.3 GO:0030242 pexophagy(GO:0030242)
1.0 5.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
1.0 18.5 GO:0018095 protein polyglutamylation(GO:0018095)
1.0 21.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
1.0 9.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.0 30.3 GO:0032836 glomerular basement membrane development(GO:0032836)
1.0 8.1 GO:0006895 Golgi to endosome transport(GO:0006895)
1.0 13.0 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
1.0 14.7 GO:0030317 sperm motility(GO:0030317)
1.0 10.6 GO:0034394 protein localization to cell surface(GO:0034394)
1.0 17.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.9 17.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.9 10.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.9 3.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.9 25.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.9 5.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.9 3.4 GO:0061010 gall bladder development(GO:0061010)
0.8 14.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.8 5.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.8 8.4 GO:0021754 facial nucleus development(GO:0021754)
0.8 4.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.8 4.1 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.8 3.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.8 3.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.8 2.4 GO:0035046 pronuclear migration(GO:0035046)
0.8 6.3 GO:0061709 reticulophagy(GO:0061709)
0.8 4.7 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.8 10.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.8 5.4 GO:0035627 ceramide transport(GO:0035627)
0.8 9.2 GO:0033198 response to ATP(GO:0033198)
0.7 0.7 GO:0010574 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575)
0.7 3.7 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.7 8.8 GO:0043279 response to nicotine(GO:0035094) response to alkaloid(GO:0043279)
0.7 2.2 GO:0009750 response to fructose(GO:0009750)
0.7 21.9 GO:0043967 histone H4 acetylation(GO:0043967)
0.7 10.2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.7 4.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.7 7.9 GO:0034982 mitochondrial protein processing(GO:0034982)
0.7 9.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.7 4.7 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.7 2.0 GO:2000425 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.7 11.9 GO:0007032 endosome organization(GO:0007032)
0.7 4.6 GO:0045905 positive regulation of translational termination(GO:0045905)
0.7 4.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.7 16.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 27.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.6 4.3 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.6 3.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.6 13.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.6 3.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 15.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.6 4.2 GO:0014812 muscle cell migration(GO:0014812)
0.6 3.6 GO:0070254 mucus secretion(GO:0070254)
0.6 9.0 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.6 7.2 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.6 12.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.6 4.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.6 7.6 GO:0009648 photoperiodism(GO:0009648)
0.6 2.3 GO:0055016 hypochord development(GO:0055016)
0.6 9.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.6 10.4 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.6 6.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.6 11.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.5 2.7 GO:0007624 ultradian rhythm(GO:0007624)
0.5 15.3 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.5 9.8 GO:0070828 heterochromatin organization(GO:0070828)
0.5 18.4 GO:0045332 phospholipid translocation(GO:0045332)
0.5 3.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.5 9.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 3.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.5 8.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.5 1.5 GO:0090231 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 2.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.5 1.5 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.5 3.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.5 3.9 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.5 15.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 6.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.5 6.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.5 1.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.5 25.9 GO:0016575 histone deacetylation(GO:0016575)
0.5 19.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.5 2.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 3.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 7.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.4 1.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.4 2.6 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.4 20.6 GO:0001841 neural tube formation(GO:0001841)
0.4 5.6 GO:1990504 dense core granule exocytosis(GO:1990504)
0.4 0.9 GO:1904427 positive regulation of calcium ion transmembrane transport(GO:1904427)
0.4 1.7 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.4 3.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.4 6.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.4 2.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 4.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.4 8.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.4 4.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.4 6.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.4 8.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.4 3.7 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.4 26.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 4.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.4 3.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4 3.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.4 8.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.4 5.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 72.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.4 12.6 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.4 4.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 7.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.4 7.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 3.7 GO:0006611 protein export from nucleus(GO:0006611)
0.4 10.4 GO:0007631 feeding behavior(GO:0007631)
0.4 2.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.4 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.4 5.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.4 3.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.4 2.2 GO:0006788 heme oxidation(GO:0006788)
0.4 9.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.4 4.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.4 3.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.4 11.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 2.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.4 1.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.3 1.0 GO:0097502 protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.3 9.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 6.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 9.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 1.0 GO:2000434 regulation of protein neddylation(GO:2000434)
0.3 2.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 4.9 GO:0009086 methionine biosynthetic process(GO:0009086)
0.3 2.9 GO:0006857 oligopeptide transport(GO:0006857)
0.3 18.9 GO:0007338 single fertilization(GO:0007338)
0.3 12.1 GO:0032456 endocytic recycling(GO:0032456)
0.3 7.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 8.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.3 10.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 7.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 4.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 1.5 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.3 0.9 GO:1903078 regulation of Golgi to plasma membrane protein transport(GO:0042996) positive regulation of Golgi to plasma membrane protein transport(GO:0042998) regulation of establishment of protein localization to plasma membrane(GO:0090003) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.3 2.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 6.0 GO:0015671 oxygen transport(GO:0015671)
0.3 3.1 GO:0019233 sensory perception of pain(GO:0019233)
0.3 1.4 GO:0080009 mRNA methylation(GO:0080009)
0.3 2.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 1.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 3.9 GO:0000266 mitochondrial fission(GO:0000266)
0.3 1.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 51.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.2 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.2 1.0 GO:1990402 embryonic liver development(GO:1990402)
0.2 3.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 1.5 GO:0090398 cellular senescence(GO:0090398)
0.2 16.4 GO:0016573 histone acetylation(GO:0016573)
0.2 1.7 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.2 0.7 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 1.7 GO:0070206 protein trimerization(GO:0070206)
0.2 1.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 2.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 1.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 2.5 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 1.6 GO:0070831 basement membrane assembly(GO:0070831)
0.2 2.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 4.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.2 17.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 17.6 GO:0042552 myelination(GO:0042552)
0.2 5.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 7.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.6 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 5.9 GO:0030111 regulation of Wnt signaling pathway(GO:0030111)
0.2 20.8 GO:0008360 regulation of cell shape(GO:0008360)
0.2 36.8 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 16.7 GO:0021782 glial cell development(GO:0021782)
0.2 7.6 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.2 3.0 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 0.6 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.2 8.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 1.4 GO:0048569 post-embryonic organ development(GO:0048569)
0.2 1.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.8 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 4.9 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.2 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.2 8.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 10.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 2.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 0.5 GO:0071033 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.2 1.0 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 3.4 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.2 5.6 GO:0031647 regulation of protein stability(GO:0031647)
0.2 3.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 2.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 1.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.2 2.7 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.2 6.9 GO:0006289 nucleotide-excision repair(GO:0006289)
0.2 92.6 GO:0031175 neuron projection development(GO:0031175)
0.2 3.0 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.2 2.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 11.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 5.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.2 4.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 5.9 GO:0048484 enteric nervous system development(GO:0048484)
0.2 5.9 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 1.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 2.9 GO:0003140 determination of left/right asymmetry in lateral mesoderm(GO:0003140)
0.2 1.5 GO:1903321 negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.1 3.6 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.1 14.4 GO:0030900 forebrain development(GO:0030900)
0.1 6.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 1.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 12.1 GO:0016236 macroautophagy(GO:0016236)
0.1 12.0 GO:0009615 response to virus(GO:0009615)
0.1 0.8 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 8.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 1.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 7.2 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 3.8 GO:0000154 rRNA modification(GO:0000154)
0.1 0.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 1.0 GO:0016540 protein autoprocessing(GO:0016540)
0.1 3.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 6.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 1.8 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.1 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 11.6 GO:0042246 tissue regeneration(GO:0042246)
0.1 2.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 2.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 3.9 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 10.8 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.1 GO:0006868 glutamine transport(GO:0006868)
0.1 3.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 2.7 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 0.3 GO:0006273 lagging strand elongation(GO:0006273) mitochondrial DNA repair(GO:0043504)
0.1 1.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 1.2 GO:0051984 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.8 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 3.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 2.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 28.8 GO:0098662 inorganic cation transmembrane transport(GO:0098662)
0.1 0.5 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 3.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.5 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 31.2 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.1 1.2 GO:1903322 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.1 4.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 18.0 GO:0006897 endocytosis(GO:0006897)
0.1 7.1 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.1 0.6 GO:0043535 regulation of endothelial cell migration(GO:0010594) regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 6.5 GO:0006979 response to oxidative stress(GO:0006979)
0.1 4.2 GO:0008037 cell recognition(GO:0008037)
0.1 3.5 GO:0030509 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.1 3.8 GO:0006821 chloride transport(GO:0006821)
0.1 23.8 GO:0006397 mRNA processing(GO:0006397)
0.1 1.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 2.1 GO:0098840 intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840)
0.1 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 2.7 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 3.0 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.1 2.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.8 GO:0014029 neural crest formation(GO:0014029)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 12.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 4.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 7.5 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.1 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.3 GO:0035282 somitogenesis(GO:0001756) segmentation(GO:0035282)
0.1 1.4 GO:0035966 response to topologically incorrect protein(GO:0035966)
0.1 4.7 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.0 1.0 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 2.2 GO:0033334 fin morphogenesis(GO:0033334)
0.0 1.3 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 1.5 GO:0042471 ear morphogenesis(GO:0042471) inner ear morphogenesis(GO:0042472)
0.0 2.1 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 1.9 GO:0006096 glycolytic process(GO:0006096)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.3 GO:0009306 protein secretion(GO:0009306)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096) exit from mitosis(GO:0010458)
0.0 1.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 2.0 GO:0007051 spindle organization(GO:0007051)
0.0 1.0 GO:0030301 sterol transport(GO:0015918) cholesterol transport(GO:0030301)
0.0 0.2 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 1.0 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 5.5 GO:0007420 brain development(GO:0007420)
0.0 0.4 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 1.5 GO:0048511 rhythmic process(GO:0048511)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.8 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 3.0 GO:0007517 muscle organ development(GO:0007517)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 2.4 GO:0006869 lipid transport(GO:0006869)
0.0 0.7 GO:0019362 pyridine nucleotide metabolic process(GO:0019362) nicotinamide nucleotide metabolic process(GO:0046496)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0006826 iron ion transport(GO:0006826)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 73.8 GO:0044295 axonal growth cone(GO:0044295)
6.0 36.0 GO:0005955 calcineurin complex(GO:0005955)
4.9 24.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
4.1 16.4 GO:0097268 cytoophidium(GO:0097268)
3.8 11.4 GO:0005828 kinetochore microtubule(GO:0005828)
3.3 3.3 GO:0044297 cell body(GO:0044297)
3.0 26.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
3.0 20.7 GO:0035517 PR-DUB complex(GO:0035517)
2.9 14.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.9 14.4 GO:0005899 insulin receptor complex(GO:0005899)
2.6 12.8 GO:0005673 transcription factor TFIIE complex(GO:0005673)
2.4 24.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.1 19.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
2.1 71.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
2.1 32.9 GO:0031209 SCAR complex(GO:0031209)
1.9 5.7 GO:0072380 TRC complex(GO:0072380)
1.8 5.5 GO:0031213 RSF complex(GO:0031213)
1.7 17.1 GO:0001669 acrosomal vesicle(GO:0001669)
1.7 6.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.6 6.6 GO:0016460 myosin II complex(GO:0016460)
1.6 22.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.6 7.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.5 7.5 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
1.4 5.6 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
1.3 5.3 GO:0016600 flotillin complex(GO:0016600)
1.3 54.8 GO:0030125 clathrin vesicle coat(GO:0030125)
1.2 38.7 GO:0031594 neuromuscular junction(GO:0031594)
1.2 25.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
1.0 16.6 GO:0030315 T-tubule(GO:0030315)
1.0 22.0 GO:0070822 Sin3-type complex(GO:0070822)
1.0 31.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.0 33.3 GO:0035869 ciliary transition zone(GO:0035869)
0.9 5.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.9 3.7 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.9 14.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.9 7.4 GO:0071914 prominosome(GO:0071914)
0.9 29.6 GO:0000421 autophagosome membrane(GO:0000421)
0.8 3.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.8 5.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.8 1.6 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.7 3.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 5.8 GO:0033010 paranodal junction(GO:0033010)
0.7 6.3 GO:0016272 prefoldin complex(GO:0016272)
0.7 9.0 GO:1990246 uniplex complex(GO:1990246)
0.7 53.8 GO:0005871 kinesin complex(GO:0005871)
0.7 3.9 GO:0000801 central element(GO:0000801)
0.7 5.2 GO:0016586 RSC complex(GO:0016586)
0.6 11.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.6 11.7 GO:0060170 ciliary membrane(GO:0060170)
0.6 26.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.6 3.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 1.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.6 3.4 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.5 7.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 4.8 GO:0071797 LUBAC complex(GO:0071797)
0.5 6.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 12.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 4.1 GO:0072487 MSL complex(GO:0072487)
0.5 2.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 7.0 GO:0030008 TRAPP complex(GO:0030008)
0.5 29.8 GO:0030427 site of polarized growth(GO:0030427)
0.5 4.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 15.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.5 2.4 GO:0033503 HULC complex(GO:0033503)
0.5 3.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.4 80.0 GO:0008021 synaptic vesicle(GO:0008021)
0.4 10.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.4 3.5 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.4 48.6 GO:0043025 neuronal cell body(GO:0043025)
0.4 6.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 2.3 GO:0070876 SOSS complex(GO:0070876)
0.4 5.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 8.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.4 11.6 GO:0032432 actin filament bundle(GO:0032432)
0.4 2.5 GO:0030897 HOPS complex(GO:0030897)
0.4 24.5 GO:0031514 motile cilium(GO:0031514)
0.4 1.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 8.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 2.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 2.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 2.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.3 15.0 GO:0048786 presynaptic active zone(GO:0048786)
0.3 7.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 6.4 GO:0008278 cohesin complex(GO:0008278)
0.3 5.8 GO:0044327 dendritic spine head(GO:0044327)
0.3 10.2 GO:0070382 exocytic vesicle(GO:0070382)
0.3 27.5 GO:0070160 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.3 26.2 GO:0030133 transport vesicle(GO:0030133)
0.3 1.3 GO:0018444 translation release factor complex(GO:0018444)
0.2 19.4 GO:0005911 cell-cell junction(GO:0005911)
0.2 68.2 GO:0005912 adherens junction(GO:0005912)
0.2 22.6 GO:0005802 trans-Golgi network(GO:0005802)
0.2 3.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 11.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 3.5 GO:0000813 ESCRT I complex(GO:0000813)
0.2 3.4 GO:0005682 U5 snRNP(GO:0005682)
0.2 28.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.2 2.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 12.5 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 20.3 GO:0000786 nucleosome(GO:0000786)
0.2 5.4 GO:0032587 ruffle membrane(GO:0032587)
0.2 2.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.2 0.8 GO:0035339 SPOTS complex(GO:0035339)
0.2 5.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.2 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 7.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 2.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 9.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.0 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.6 GO:0045095 keratin filament(GO:0045095)
0.2 12.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 2.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 77.6 GO:0043005 neuron projection(GO:0043005)
0.1 1.2 GO:0030670 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.1 2.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 10.5 GO:0005884 actin filament(GO:0005884)
0.1 8.8 GO:0030018 Z disc(GO:0030018)
0.1 7.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 4.4 GO:0005814 centriole(GO:0005814)
0.1 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 12.8 GO:0005681 spliceosomal complex(GO:0005681)
0.1 0.5 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 2.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 15.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 32.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 9.3 GO:0005770 late endosome(GO:0005770)
0.1 121.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.6 GO:0005844 polysome(GO:0005844)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 34.4 GO:0031012 extracellular matrix(GO:0031012)
0.1 7.9 GO:0005769 early endosome(GO:0005769)
0.1 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 52.6 GO:0005794 Golgi apparatus(GO:0005794)
0.1 4.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0060091 kinocilium(GO:0060091) kinociliary basal body(GO:1902636)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.5 GO:0030496 midbody(GO:0030496)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 13.2 GO:0042995 cell projection(GO:0042995)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.1 GO:0034703 cation channel complex(GO:0034703)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 3.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 4.4 GO:0005874 microtubule(GO:0005874)
0.0 1.6 GO:0030027 lamellipodium(GO:0030027)
0.0 59.9 GO:0005886 plasma membrane(GO:0005886)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 47.8 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
7.7 23.2 GO:0031701 angiotensin receptor binding(GO:0031701)
6.0 36.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
5.7 45.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.1 16.4 GO:0003883 CTP synthase activity(GO:0003883)
4.0 24.2 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
3.8 26.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.6 14.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
3.4 20.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.2 16.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
2.9 14.4 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
2.8 11.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
2.7 64.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
2.5 35.4 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
2.5 7.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
2.4 7.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
2.4 9.5 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
2.2 37.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
2.2 15.6 GO:0030274 LIM domain binding(GO:0030274)
2.2 11.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.1 33.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
2.1 10.4 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
2.0 35.9 GO:0033691 sialic acid binding(GO:0033691)
1.9 24.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.8 36.1 GO:0004890 GABA-A receptor activity(GO:0004890)
1.8 14.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.7 8.6 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
1.7 10.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.7 6.7 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
1.7 39.8 GO:0001540 beta-amyloid binding(GO:0001540)
1.6 6.6 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
1.6 53.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.6 7.8 GO:0008046 axon guidance receptor activity(GO:0008046)
1.6 23.3 GO:0051117 ATPase binding(GO:0051117)
1.5 32.2 GO:0050811 GABA receptor binding(GO:0050811)
1.5 26.4 GO:0004383 guanylate cyclase activity(GO:0004383)
1.5 29.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
1.4 7.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.4 14.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.4 5.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.4 12.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.4 17.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
1.3 40.1 GO:0030165 PDZ domain binding(GO:0030165)
1.3 9.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.3 18.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
1.3 4.0 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
1.3 5.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.3 10.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.3 11.4 GO:0043515 kinetochore binding(GO:0043515)
1.2 32.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
1.2 18.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.1 7.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.1 15.5 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 8.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 5.4 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
1.1 4.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.0 8.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
1.0 5.1 GO:0046592 polyamine oxidase activity(GO:0046592)
1.0 11.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 3.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.9 20.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 5.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.9 3.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.9 16.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.9 4.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.9 3.5 GO:0035197 siRNA binding(GO:0035197)
0.9 4.3 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.8 5.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.8 10.8 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.8 4.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.8 4.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.8 3.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.8 15.9 GO:0003785 actin monomer binding(GO:0003785)
0.8 3.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.8 9.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.8 2.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.8 7.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 19.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 13.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.7 6.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.7 4.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.7 14.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.7 6.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.7 8.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 4.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.7 34.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.7 4.7 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.7 2.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 3.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 16.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.6 16.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.6 12.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.6 4.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 1.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.6 9.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 4.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.6 5.9 GO:0005522 profilin binding(GO:0005522)
0.6 23.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.6 2.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.6 1.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 5.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.5 5.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 21.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.5 1.6 GO:0045545 syndecan binding(GO:0045545)
0.5 25.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.5 2.7 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.5 3.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.5 26.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.5 1.6 GO:0032027 myosin light chain binding(GO:0032027)
0.5 3.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.5 12.6 GO:0031267 small GTPase binding(GO:0031267)
0.5 6.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 4.1 GO:0015232 heme transporter activity(GO:0015232)
0.5 7.2 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.5 2.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 4.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 19.0 GO:0043130 ubiquitin binding(GO:0043130)
0.5 54.9 GO:0019208 phosphatase regulator activity(GO:0019208)
0.5 15.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 4.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 4.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.4 2.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 3.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.4 3.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.4 15.0 GO:0019003 GDP binding(GO:0019003)
0.4 7.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.4 10.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.4 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 10.4 GO:0031491 nucleosome binding(GO:0031491)
0.3 8.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 2.0 GO:0001727 lipid kinase activity(GO:0001727)
0.3 1.7 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 1.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.3 4.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 2.4 GO:0016917 GABA receptor activity(GO:0016917)
0.3 8.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.9 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 0.9 GO:0071253 connexin binding(GO:0071253)
0.3 3.0 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.3 2.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 2.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.3 5.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 11.4 GO:0044325 ion channel binding(GO:0044325)
0.3 6.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 6.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.3 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.3 3.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 2.9 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.3 4.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 2.6 GO:0005042 netrin receptor activity(GO:0005042)
0.3 91.8 GO:0015631 tubulin binding(GO:0015631)
0.2 3.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 41.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 1.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 5.1 GO:0042056 chemoattractant activity(GO:0042056)
0.2 10.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 4.4 GO:0015026 coreceptor activity(GO:0015026)
0.2 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 2.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 20.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 28.7 GO:0005516 calmodulin binding(GO:0005516)
0.2 39.9 GO:0042802 identical protein binding(GO:0042802)
0.2 26.4 GO:0000287 magnesium ion binding(GO:0000287)
0.2 4.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 11.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.2 1.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 3.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 3.0 GO:0016208 AMP binding(GO:0016208)
0.2 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 5.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 0.7 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.2 0.9 GO:0060182 apelin receptor activity(GO:0060182)
0.2 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 8.5 GO:0071949 FAD binding(GO:0071949)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 4.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.8 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.2 4.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 7.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 32.3 GO:0003682 chromatin binding(GO:0003682)
0.1 18.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 21.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 5.4 GO:0030276 clathrin binding(GO:0030276)
0.1 2.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 2.0 GO:0002039 p53 binding(GO:0002039)
0.1 2.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 42.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.1 GO:0005272 sodium channel activity(GO:0005272)
0.1 4.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 3.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 4.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.4 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 41.3 GO:0003924 GTPase activity(GO:0003924)
0.1 3.0 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 3.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0010181 FMN binding(GO:0010181)
0.1 1.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 4.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 4.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 13.1 GO:0046983 protein dimerization activity(GO:0046983)
0.1 4.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.0 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 8.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 35.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.2 25.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
1.1 9.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.0 43.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.0 22.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
1.0 9.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.9 52.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.8 11.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.7 6.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.7 14.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 8.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.4 5.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 5.3 PID CONE PATHWAY Visual signal transduction: Cones
0.4 21.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.3 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.3 9.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 4.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 3.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 9.5 PID BMP PATHWAY BMP receptor signaling
0.2 7.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 2.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 4.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 4.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.2 3.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 1.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 3.8 PID FOXO PATHWAY FoxO family signaling
0.1 2.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.3 PID ATM PATHWAY ATM pathway
0.1 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 44.6 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
4.1 20.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
4.1 61.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
3.5 59.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.8 9.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.6 34.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
1.2 14.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 54.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.9 8.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.8 10.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.7 8.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.7 7.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.7 4.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.6 11.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.6 5.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 4.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 7.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.6 8.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.6 5.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.5 5.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 5.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 4.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 5.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 3.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4 6.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 5.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 12.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 5.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 2.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 3.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 3.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.3 2.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 2.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 12.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 1.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.3 2.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 13.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 2.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 7.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 1.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 5.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 2.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 6.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 12.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 2.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 4.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 5.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives