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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxb1b+foxb2

Z-value: 1.29

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Transcription factors associated with foxb1b+foxb2

Gene Symbol Gene ID Gene Info
ENSDARG00000037475 forkhead box B2
ENSDARG00000053650 forkhead box B1b
ENSDARG00000110408 forkhead box B1b
ENSDARG00000113373 forkhead box B1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxb1bdr11_v1_chr7_+_29461060_294610600.683.5e-14Click!
foxb2dr11_v1_chr8_-_38506339_385063390.618.4e-11Click!

Activity profile of foxb1b+foxb2 motif

Sorted Z-values of foxb1b+foxb2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_19953089 18.22 ENSDART00000153828
ATPase plasma membrane Ca2+ transporting 3b
chr23_-_27633730 10.51 ENSDART00000103639
ADP-ribosylation factor 3a
chr6_+_36942966 10.24 ENSDART00000028895
neuronal growth regulator 1
chr20_-_34801181 9.87 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr4_+_8797197 9.80 ENSDART00000158671
sulfotransferase family 4A, member 1
chr12_+_28367557 9.75 ENSDART00000066294
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr14_-_7885707 9.34 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr14_-_26177156 9.32 ENSDART00000014149
FAT atypical cadherin 2
chr19_+_10396042 9.25 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr23_-_29502287 8.89 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr6_-_9792004 8.88 ENSDART00000081129
cyclin-dependent kinase 15
chr16_-_43025885 8.77 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr16_-_12173554 8.73 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr21_+_11684830 8.28 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr15_+_37105986 8.20 ENSDART00000157762
amyloid beta (A4) precursor-like protein 1
chr2_-_8017579 8.13 ENSDART00000040209
eph receptor B3a
chr1_+_16127825 7.99 ENSDART00000122503
tumor suppressor candidate 3
chr2_-_24462277 7.85 ENSDART00000033922
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr2_+_24177006 7.53 ENSDART00000132582
microtubule associated protein 4 like
chr14_-_49063157 7.11 ENSDART00000021260
septin 8b
chr16_+_46000956 6.97 ENSDART00000101753
ENSDART00000162393
myotubularin related protein 11
chr21_+_11685009 6.96 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr24_-_4973765 6.95 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr9_-_44295071 6.90 ENSDART00000011837
neuronal differentiation 1
chr3_+_19207176 6.86 ENSDART00000087803
relaxin 3a
chr2_+_29976419 6.85 ENSDART00000056748
engrailed homeobox 2b
chr1_-_28749604 6.85 ENSDART00000148522
zgc:172295
chr8_-_25120231 6.84 ENSDART00000147308
adhesion molecule with Ig-like domain 1
chr14_-_17599452 6.83 ENSDART00000080042
RAB33A, member RAS oncogene family
chr21_+_30563115 6.67 ENSDART00000028566
si:ch211-200p22.4
chr4_+_17280868 6.58 ENSDART00000145349
branched chain amino-acid transaminase 1, cytosolic
chr13_+_1100197 6.51 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr1_+_53954230 6.50 ENSDART00000037729
ENSDART00000159900
centriole, cilia and spindle-associated protein a
chr18_-_14734678 6.40 ENSDART00000142462
teashirt zinc finger homeobox 3a
chr10_-_15405564 6.38 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_+_25801648 6.35 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr6_-_40744720 6.33 ENSDART00000154916
ENSDART00000186922
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_-_20287530 6.31 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr14_-_34044369 6.25 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr20_-_19590378 6.22 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr19_+_6938289 6.14 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr14_-_25599002 6.11 ENSDART00000040955
solute carrier family 25, member 48
chr7_+_7019911 6.11 ENSDART00000172421
RNA binding motif protein 14b
chr25_-_15049694 6.10 ENSDART00000162485
ENSDART00000164384
ENSDART00000165632
ENSDART00000159490
paired box 6a
chr6_-_32999646 6.06 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr6_+_23752593 6.06 ENSDART00000164366
zgc:158654
chr11_-_29833698 6.03 ENSDART00000079149
X-linked Kx blood group (McLeod syndrome)
chr11_-_4235811 5.96 ENSDART00000121716
si:ch211-236d3.4
chr18_+_24922125 5.91 ENSDART00000180385
repulsive guidance molecule family member a
chr12_+_31729075 5.89 ENSDART00000152973
si:dkey-49c17.3
chr20_+_25486206 5.89 ENSDART00000172076
hook microtubule-tethering protein 1
chr10_+_25219728 5.82 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr12_-_19346678 5.78 ENSDART00000044860
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr3_+_34821327 5.72 ENSDART00000055262
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr17_-_40397752 5.69 ENSDART00000178483

chr22_+_27090136 5.64 ENSDART00000136770
si:dkey-246e1.3
chr3_-_26341959 5.63 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
chr6_+_40671336 5.61 ENSDART00000111639
ENSDART00000186617
arginine-glutamic acid dipeptide (RE) repeats b
chr7_-_32782430 5.57 ENSDART00000173808
growth arrest-specific 2b
chr6_-_13187168 5.54 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr7_+_48288762 5.52 ENSDART00000083569
ornithine decarboxylase antizyme 2b
chr7_-_31941670 5.42 ENSDART00000180929
ENSDART00000075389
brain-derived neurotrophic factor
chr6_-_30658755 5.41 ENSDART00000065215
ENSDART00000181302
leucine rich adaptor protein 1
chr21_+_20901505 5.40 ENSDART00000132741
complement component 7b
chr23_-_3703569 5.31 ENSDART00000143731
protein kinase C and casein kinase substrate in neurons 1a
chr7_+_48460239 5.26 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr2_+_24177190 5.25 ENSDART00000099546
microtubule associated protein 4 like
chr21_-_29100110 5.19 ENSDART00000142598
T cell immunoglobulin and mucin domain containing 4
chr21_-_30284404 5.18 ENSDART00000066363
zgc:175066
chr19_-_28367413 5.14 ENSDART00000079092
si:dkey-261i16.5
chr2_+_26240631 5.11 ENSDART00000129895
paralemmin 1b
chr13_+_32446169 5.10 ENSDART00000143325
5'-nucleotidase, cytosolic IB a
chr1_-_10473630 5.08 ENSDART00000040116
trinucleotide repeat containing 5
chr9_+_38163876 5.04 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr20_-_19365875 4.96 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr6_-_13408680 4.96 ENSDART00000151566
formin-like 2b
chr4_+_6643421 4.95 ENSDART00000099462
G protein-coupled receptor 85
chr13_-_21701323 4.94 ENSDART00000164112
si:dkey-191g9.7
chr11_+_18873619 4.93 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr24_-_6678640 4.84 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr4_+_8168514 4.81 ENSDART00000150830
ninjurin 2
chr14_-_4682114 4.79 ENSDART00000014454
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr5_-_46896541 4.78 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr18_+_17428506 4.75 ENSDART00000100223
zgc:91860
chr16_-_17162843 4.75 ENSDART00000089386
intermediate filament family orphan 1b
chr16_-_52879741 4.64 ENSDART00000166470
tubulin polymerization promoting protein
chr17_-_43391499 4.60 ENSDART00000189280
inositol-tetrakisphosphate 1-kinase b
chr5_+_52625975 4.59 ENSDART00000170341
ENSDART00000168317
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr16_-_37470042 4.59 ENSDART00000142916
si:ch211-208k15.1
chr22_+_20195280 4.59 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr17_+_31221761 4.56 ENSDART00000155580
coiled-coil domain containing 32
chr18_+_7286788 4.53 ENSDART00000022998
si:ch73-86n2.1
chr19_+_24039830 4.53 ENSDART00000100422
Ras-like without CAAX 1
chr9_+_29603649 4.53 ENSDART00000140477
mcf.2 cell line derived transforming sequence-like b
chr19_+_16032383 4.50 ENSDART00000046530
RAB42, member RAS oncogene family a
chr10_+_34426256 4.42 ENSDART00000102566
neurobeachin a
chr3_-_51912019 4.41 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr18_-_39787040 4.40 ENSDART00000169916
Dmx-like 2
chr9_+_33154841 4.39 ENSDART00000132465
dopey family member 2
chr23_-_29505463 4.37 ENSDART00000050915
kinesin family member 1B
chr12_-_4781801 4.37 ENSDART00000167490
ENSDART00000121718
microtubule-associated protein tau a
chr18_+_27337994 4.36 ENSDART00000136172
si:dkey-29p10.4
chr3_-_26191960 4.35 ENSDART00000113843
yippee-like 3
chr23_+_31405497 4.32 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr19_+_5604241 4.31 ENSDART00000011025
WAS/WASL interacting protein family, member 2b
chr5_-_40190949 4.31 ENSDART00000175588
WD repeat and FYVE domain containing 3
chr10_+_22891126 4.27 ENSDART00000057291
arrestin, beta 2a
chr6_-_39605734 4.27 ENSDART00000044276
ENSDART00000179059
disco-interacting protein 2 homolog Bb
chr3_-_28258462 4.26 ENSDART00000191573
RNA binding fox-1 homolog 1
chr16_+_28578352 4.23 ENSDART00000149306
N-myristoyltransferase 2
chr13_-_22903246 4.21 ENSDART00000089133
RUN and FYVE domain containing 2
chr2_-_11662851 4.19 ENSDART00000145108
zgc:110130
chr13_-_49169545 4.18 ENSDART00000192076
translin-associated factor X
chr19_+_32979331 4.17 ENSDART00000078066
spire-type actin nucleation factor 1a
chr15_+_8043751 4.17 ENSDART00000193701
cell adhesion molecule 2b
chr24_-_21989406 4.14 ENSDART00000032963
apolipoprotein O, b
chr7_+_52712807 4.11 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr11_-_24191928 4.10 ENSDART00000136827
SRY (sex determining region Y)-box 12
chr20_+_42918755 4.10 ENSDART00000134855
EFR3 homolog Bb (S. cerevisiae)
chr20_-_26039841 4.07 ENSDART00000179929
si:dkey-12h9.6
chr5_-_46980651 4.07 ENSDART00000181022
ENSDART00000168038
EGF-like repeats and discoidin I-like domains 3a
chr24_-_22756508 4.03 ENSDART00000035409
ENSDART00000146247
zinc finger, C2HC-type containing 1A
chr15_-_18574716 4.03 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr20_+_40457599 4.01 ENSDART00000017553
serine incorporator 1
chr13_-_12006007 3.94 ENSDART00000111438
meningioma expressed antigen 5 (hyaluronidase)
chr1_-_40994259 3.91 ENSDART00000101562
adrenoceptor alpha 2C
chr2_-_42173834 3.91 ENSDART00000098357
ENSDART00000144707
solute carrier family 39 (zinc transporter), member 6
chr6_-_21616659 3.89 ENSDART00000074256
protein phosphatase 1, regulatory subunit 12C
chr2_+_25929619 3.87 ENSDART00000137746
solute carrier family 7, member 14a
chr20_+_30445971 3.86 ENSDART00000153150
myelin transcription factor 1-like, a
chr11_+_6819050 3.86 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr13_-_11378355 3.85 ENSDART00000164566
v-akt murine thymoma viral oncogene homolog 3a
chr2_-_3403020 3.85 ENSDART00000092741
synaptosomal-associated protein, 47
chr3_+_32403758 3.83 ENSDART00000156982
si:ch211-195b15.8
chr23_-_36449111 3.80 ENSDART00000110478
zgc:174906
chr9_+_38962398 3.79 ENSDART00000134294
microtubule-associated protein 2
chr18_-_13121983 3.77 ENSDART00000092648
ribitol xylosyltransferase 1
chr8_-_25716074 3.74 ENSDART00000007482
testis specific protein, Y-linked
chr14_-_4273396 3.72 ENSDART00000127318
FERM and PDZ domain containing 1b
chr5_+_51111343 3.70 ENSDART00000092002
protein-O-mannosyltransferase 1
chr23_+_19594608 3.69 ENSDART00000134865
sarcolemma associated protein b
chr19_-_7358184 3.69 ENSDART00000092379
oxidation resistance 1b
chr5_+_15495351 3.67 ENSDART00000111646
ENSDART00000114446
SDS3 homolog, SIN3A corepressor complex component
chr11_+_29770966 3.67 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr23_-_15330168 3.66 ENSDART00000035865
ENSDART00000143635
sulfatase 2b
chr13_-_40499296 3.62 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr18_-_41219790 3.61 ENSDART00000162387
ENSDART00000193753
zinc finger and BTB domain containing 38
chr25_+_10458990 3.61 ENSDART00000130354
ENSDART00000044738
RIC8 guanine nucleotide exchange factor A
chr5_-_66749535 3.60 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr12_+_18578597 3.58 ENSDART00000134944
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr14_+_4276394 3.54 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr9_+_19623363 3.53 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pyridoxal (pyridoxine, vitamin B6) kinase a
chr4_-_14207471 3.47 ENSDART00000015134
twinfilin actin-binding protein 1b
chr13_-_12005429 3.47 ENSDART00000180302
meningioma expressed antigen 5 (hyaluronidase)
chr10_+_22890791 3.45 ENSDART00000176011
arrestin, beta 2a
chr9_-_3149896 3.45 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr16_-_12173399 3.45 ENSDART00000142574
calsyntenin 3
chr12_-_32066469 3.43 ENSDART00000140685
ENSDART00000062185
RAB40B, member RAS oncogene family
chr23_-_30764319 3.40 ENSDART00000075918
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr13_-_18691041 3.40 ENSDART00000057867
sideroflexin 3
chr1_+_21937201 3.39 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr12_-_7607114 3.37 ENSDART00000158095
solute carrier family 16, member 9b
chr2_-_40135942 3.36 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr19_+_20178978 3.34 ENSDART00000145115
ENSDART00000151175
transformer 2 alpha homolog
chr17_-_13026634 3.33 ENSDART00000113713
family with sequence similarity 177, member A1
chr5_-_25236340 3.31 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr25_+_15647993 3.31 ENSDART00000186578
ENSDART00000031828
spondin 1b
chr22_+_10713713 3.29 ENSDART00000122349
hippocampus abundant transcript 1b
chr20_+_29217835 3.29 ENSDART00000024528
ER membrane protein complex subunit 7
chr5_+_34981584 3.28 ENSDART00000134795
ankyrin repeat, family A (RFXANK-like), 2
chr16_+_5612547 3.26 ENSDART00000140226
ENSDART00000189352
si:dkey-283b15.4
chr11_+_30162407 3.25 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr7_-_31618166 3.24 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr24_-_20658446 3.23 ENSDART00000127923
natural killer cell triggering receptor
chr21_-_4032650 3.22 ENSDART00000151648
netrin g2b
chr12_+_27213733 3.21 ENSDART00000133048
neighbor of brca1 gene 1a
chr7_+_22823889 3.21 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
phosphorylase, glycogen, muscle b
chr5_-_28767573 3.19 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr13_+_28612313 3.19 ENSDART00000077383
BLOC-1 related complex subunit 7
chr2_+_26240339 3.17 ENSDART00000191006
paralemmin 1b
chr18_-_30020879 3.17 ENSDART00000162086
si:ch211-220f16.2
chr6_-_1553314 3.15 ENSDART00000077209
transmembrane protein, adipocyte asscociated 1
chr18_+_19419120 3.14 ENSDART00000025107
mitogen-activated protein kinase kinase 1
chr6_-_8392104 3.14 ENSDART00000081561
ENSDART00000181178
interleukin enhancer binding factor 3a
chr14_-_2352384 3.13 ENSDART00000170666
si:ch73-233f7.7
chr13_+_22280983 3.12 ENSDART00000173258
ENSDART00000173379
ubiquitin specific peptidase 54a
chr25_+_388258 3.12 ENSDART00000166834
regulatory factor X7b
chr11_-_18601955 3.12 ENSDART00000180565
zinc finger, MYND-type containing 8
chr5_+_61799629 3.12 ENSDART00000113508
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr3_+_25907266 3.12 ENSDART00000170324
ENSDART00000192633
target of myb1 membrane trafficking protein
chr6_+_13933464 3.10 ENSDART00000109144
protein tyrosine phosphatase, receptor type, Nb
chr3_-_18792492 3.10 ENSDART00000134208
ENSDART00000034373
hydroxyacylglutathione hydrolase
chr17_+_20173882 3.08 ENSDART00000155379
si:ch211-248a14.8
chr10_-_32880298 3.08 ENSDART00000138243
RAB guanine nucleotide exchange factor (GEF) 1
chr7_+_48805534 3.05 ENSDART00000145375
ENSDART00000148744
carnitine palmitoyltransferase 1Aa (liver)
chr2_+_38924975 3.04 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr19_-_19025998 3.04 ENSDART00000186156
ENSDART00000163359
ENSDART00000167951
dynein, cytoplasmic 1, light intermediate chain 1
chr2_-_54054225 3.01 ENSDART00000167239

chr21_+_8427059 2.99 ENSDART00000143151
DENN/MADD domain containing 1A
chr4_-_4261673 2.98 ENSDART00000150694
CD9 molecule b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1b+foxb2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.8 GO:0048917 posterior lateral line ganglion development(GO:0048917)
2.3 20.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
2.1 6.4 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
2.0 6.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
1.9 5.8 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.9 11.6 GO:0035881 amacrine cell differentiation(GO:0035881)
1.9 7.7 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
1.7 5.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.6 6.6 GO:0009098 leucine biosynthetic process(GO:0009098)
1.6 6.4 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.5 4.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.5 6.1 GO:0006844 acyl carnitine transport(GO:0006844)
1.5 4.4 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
1.3 3.9 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.2 5.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.2 3.5 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
1.2 3.5 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.1 4.6 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
1.1 1.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.1 3.2 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.0 3.1 GO:0006089 lactate metabolic process(GO:0006089)
1.0 15.2 GO:0016486 peptide hormone processing(GO:0016486)
1.0 6.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
1.0 8.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
1.0 2.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.0 2.9 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.9 6.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.9 6.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.8 2.5 GO:0071514 genetic imprinting(GO:0071514)
0.8 5.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.8 4.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.8 3.9 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.8 4.6 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.7 4.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.7 11.6 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.7 3.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.7 2.7 GO:0090299 regulation of neural crest formation(GO:0090299)
0.7 3.4 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.6 1.9 GO:0001779 natural killer cell differentiation(GO:0001779)
0.6 3.0 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.6 1.8 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.6 1.8 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.6 2.8 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.5 2.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.5 5.4 GO:0061709 reticulophagy(GO:0061709)
0.5 8.0 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.5 2.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.5 4.2 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.5 6.3 GO:0001964 startle response(GO:0001964)
0.5 5.4 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.5 8.5 GO:0007413 axonal fasciculation(GO:0007413)
0.5 8.0 GO:0015693 magnesium ion transport(GO:0015693)
0.5 9.4 GO:0007032 endosome organization(GO:0007032)
0.5 2.8 GO:0003232 bulbus arteriosus development(GO:0003232)
0.5 1.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 2.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 3.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 6.0 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.4 2.6 GO:0003272 endocardial cushion formation(GO:0003272)
0.4 6.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.4 1.2 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.4 0.4 GO:0061195 tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195)
0.4 2.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.4 2.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 9.8 GO:0051923 sulfation(GO:0051923)
0.3 2.0 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.3 3.7 GO:0046548 retinal rod cell development(GO:0046548)
0.3 6.3 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.3 2.3 GO:0045905 positive regulation of translational termination(GO:0045905)
0.3 5.6 GO:0051764 actin crosslink formation(GO:0051764)
0.3 3.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 2.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 3.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.3 8.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 1.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.5 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 1.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.5 GO:0001839 neural plate morphogenesis(GO:0001839)
0.3 1.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.3 1.8 GO:1990108 protein linear deubiquitination(GO:1990108)
0.3 1.7 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.3 0.9 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 2.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 2.0 GO:0003352 regulation of cilium movement(GO:0003352)
0.3 1.4 GO:0031627 telomeric loop formation(GO:0031627)
0.3 12.4 GO:0021854 hypothalamus development(GO:0021854)
0.3 4.1 GO:0042407 cristae formation(GO:0042407)
0.3 1.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.3 3.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 2.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 3.7 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3 1.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 2.0 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.2 2.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 0.7 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 0.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 1.4 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 5.5 GO:0006595 polyamine metabolic process(GO:0006595)
0.2 1.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.2 2.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.6 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 6.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.3 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.2 0.9 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.2 0.9 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.2 9.9 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.2 4.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 5.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 0.9 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.2 2.9 GO:0030317 sperm motility(GO:0030317)
0.2 4.8 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.2 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 3.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 0.6 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.2 1.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 1.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 5.4 GO:0019835 cytolysis(GO:0019835)
0.2 2.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.2 3.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 1.1 GO:0070254 mucus secretion(GO:0070254)
0.2 1.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.2 3.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.2 1.3 GO:0035627 ceramide transport(GO:0035627)
0.2 0.7 GO:0061010 gall bladder development(GO:0061010)
0.2 0.7 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 1.7 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 2.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.8 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 4.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 4.2 GO:0030307 positive regulation of cell growth(GO:0030307)
0.2 7.1 GO:0030901 midbrain development(GO:0030901)
0.2 1.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 6.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 5.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 2.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 2.0 GO:0014812 muscle cell migration(GO:0014812)
0.1 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.5 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 2.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 2.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.0 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 3.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 2.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 2.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 3.8 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 6.8 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 4.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.8 GO:0007612 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.7 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 3.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 6.2 GO:0007416 synapse assembly(GO:0007416)
0.1 10.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 2.0 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488)
0.1 0.4 GO:0010259 multicellular organism aging(GO:0010259)
0.1 2.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.2 GO:0021986 habenula development(GO:0021986)
0.1 2.4 GO:0060972 left/right pattern formation(GO:0060972)
0.1 2.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.1 1.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.3 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 2.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 4.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 7.8 GO:0008360 regulation of cell shape(GO:0008360)
0.1 4.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 2.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 2.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.2 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 7.5 GO:0006865 amino acid transport(GO:0006865)
0.1 4.3 GO:0048916 posterior lateral line development(GO:0048916)
0.1 2.5 GO:0001841 neural tube formation(GO:0001841)
0.1 1.3 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.1 2.2 GO:0007031 peroxisome organization(GO:0007031)
0.1 1.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.9 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 2.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.9 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.6 GO:0019233 sensory perception of pain(GO:0019233)
0.1 1.6 GO:0000154 rRNA modification(GO:0000154)
0.1 4.7 GO:0009615 response to virus(GO:0009615)
0.1 0.2 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.1 3.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 11.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.8 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 1.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 20.3 GO:0006397 mRNA processing(GO:0006397)
0.0 2.6 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.7 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 1.9 GO:0022406 membrane docking(GO:0022406) vesicle docking(GO:0048278)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.7 GO:0016236 macroautophagy(GO:0016236)
0.0 2.7 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 3.4 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 3.6 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 3.5 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.2 GO:0009636 response to toxic substance(GO:0009636)
0.0 8.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 2.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 2.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 14.2 GO:0031175 neuron projection development(GO:0031175)
0.0 2.7 GO:0007051 spindle organization(GO:0007051)
0.0 1.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 0.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 5.5 GO:0006869 lipid transport(GO:0006869)
0.0 0.5 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 2.1 GO:0016573 histone acetylation(GO:0016573)
0.0 1.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0016116 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 7.8 GO:0098662 inorganic cation transmembrane transport(GO:0098662)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 4.2 GO:0006897 endocytosis(GO:0006897)
0.0 2.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.0 GO:0090630 activation of GTPase activity(GO:0090630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.1 6.4 GO:0072380 TRC complex(GO:0072380)
1.7 5.0 GO:0005828 kinetochore microtubule(GO:0005828)
1.6 9.3 GO:0005955 calcineurin complex(GO:0005955)
1.5 6.1 GO:0016600 flotillin complex(GO:0016600)
1.1 4.6 GO:0035339 SPOTS complex(GO:0035339)
1.1 4.4 GO:0043291 RAVE complex(GO:0043291)
1.1 3.3 GO:0032839 dendrite cytoplasm(GO:0032839)
1.0 5.9 GO:0070695 FHF complex(GO:0070695)
0.8 2.5 GO:0031213 RSF complex(GO:0031213)
0.6 6.7 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.6 8.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 4.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 3.8 GO:0031931 TORC1 complex(GO:0031931)
0.4 1.7 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.4 2.1 GO:0005899 insulin receptor complex(GO:0005899)
0.4 1.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 6.1 GO:0031209 SCAR complex(GO:0031209)
0.4 4.1 GO:0061617 MICOS complex(GO:0061617)
0.3 1.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 2.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 5.4 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.7 GO:0016586 RSC complex(GO:0016586)
0.3 9.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 2.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 1.2 GO:0017177 glucosidase II complex(GO:0017177)
0.3 2.5 GO:0072487 MSL complex(GO:0072487)
0.3 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 1.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 7.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 2.8 GO:0000812 Swr1 complex(GO:0000812)
0.3 11.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.3 2.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.3 1.9 GO:0030897 HOPS complex(GO:0030897)
0.3 1.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 0.9 GO:0097268 cytoophidium(GO:0097268)
0.2 3.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.5 GO:0043194 axon initial segment(GO:0043194)
0.2 4.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 6.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 1.0 GO:0071203 WASH complex(GO:0071203)
0.2 4.6 GO:0043195 terminal bouton(GO:0043195)
0.2 16.4 GO:0005871 kinesin complex(GO:0005871)
0.2 6.3 GO:0035869 ciliary transition zone(GO:0035869)
0.2 2.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 3.9 GO:0070822 Sin3-type complex(GO:0070822)
0.2 5.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 4.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 6.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.9 GO:0055087 Ski complex(GO:0055087)
0.2 1.7 GO:0005858 axonemal dynein complex(GO:0005858)
0.2 1.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 4.0 GO:0035102 PRC1 complex(GO:0035102)
0.2 1.3 GO:0033010 paranodal junction(GO:0033010)
0.2 25.1 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.3 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 3.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 5.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.7 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 16.0 GO:0030133 transport vesicle(GO:0030133)
0.1 8.9 GO:0014069 postsynaptic density(GO:0014069)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 5.9 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 4.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 5.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.9 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 1.3 GO:0097346 INO80-type complex(GO:0097346)
0.1 26.1 GO:0005874 microtubule(GO:0005874)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 11.8 GO:0005681 spliceosomal complex(GO:0005681)
0.1 16.0 GO:0098791 Golgi subcompartment(GO:0098791)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 7.9 GO:0043025 neuronal cell body(GO:0043025)
0.1 3.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 8.9 GO:0005769 early endosome(GO:0005769)
0.1 1.8 GO:0030496 midbody(GO:0030496)
0.1 3.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 10.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 2.9 GO:0031514 motile cilium(GO:0031514)
0.1 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 2.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 5.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 27.1 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.5 GO:0030424 axon(GO:0030424)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 5.2 GO:0005912 adherens junction(GO:0005912)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 25.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 2.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0005635 nuclear envelope(GO:0005635)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0031701 angiotensin receptor binding(GO:0031701)
1.6 6.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.6 9.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
1.5 4.6 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
1.5 6.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
1.4 5.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.2 15.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.2 3.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.9 2.7 GO:0051765 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
0.9 8.9 GO:0030332 cyclin binding(GO:0030332)
0.9 7.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 5.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.8 2.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 2.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.7 2.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.7 11.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.7 2.7 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.7 2.7 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.7 19.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.7 3.9 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.6 3.2 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.6 8.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 1.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.6 3.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.6 3.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.6 2.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.6 7.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 5.0 GO:0043515 kinetochore binding(GO:0043515)
0.5 8.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.5 6.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.5 1.9 GO:0035197 siRNA binding(GO:0035197)
0.5 1.9 GO:0030626 U12 snRNA binding(GO:0030626)
0.5 1.8 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4 14.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.8 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4 3.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 3.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.1 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.4 1.2 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.4 2.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 9.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 5.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.1 GO:0045545 syndecan binding(GO:0045545)
0.4 6.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 2.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 4.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.3 2.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 3.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 1.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 6.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 2.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 1.5 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 3.8 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.3 1.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 0.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 3.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 4.9 GO:0015026 coreceptor activity(GO:0015026)
0.3 1.3 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.3 2.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 2.5 GO:0005537 mannose binding(GO:0005537)
0.2 1.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 0.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.2 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 5.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 3.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 5.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.2 2.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 2.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.2 7.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 3.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 5.9 GO:0019003 GDP binding(GO:0019003)
0.2 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.2 7.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 2.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 3.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 2.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 3.4 GO:0031267 small GTPase binding(GO:0031267)
0.1 2.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 48.7 GO:0015631 tubulin binding(GO:0015631)
0.1 3.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.4 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 9.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 5.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 9.4 GO:0043130 ubiquitin binding(GO:0043130)
0.1 6.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 16.9 GO:0060090 binding, bridging(GO:0060090)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.2 GO:0016208 AMP binding(GO:0016208)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 3.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.5 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.3 GO:0070513 death domain binding(GO:0070513)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 3.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.9 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 4.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 14.1 GO:0042802 identical protein binding(GO:0042802)
0.1 2.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 3.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.7 GO:0008201 heparin binding(GO:0008201)
0.1 1.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.3 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 6.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 3.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 2.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 15.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0008443 6-phosphofructo-2-kinase activity(GO:0003873) phosphofructokinase activity(GO:0008443)
0.0 4.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 21.3 GO:0005525 GTP binding(GO:0005525)
0.0 1.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 3.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 8.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 5.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.3 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.9 GO:0015278 calcium-release channel activity(GO:0015278)
0.0 1.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 7.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.5 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0051213 dioxygenase activity(GO:0051213)
0.0 10.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 2.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 3.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 1.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 12.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.4 PID ARF6 PATHWAY Arf6 signaling events
0.2 2.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 3.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 6.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 2.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 4.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.0 PID BMP PATHWAY BMP receptor signaling
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 6.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.7 PID ATM PATHWAY ATM pathway
0.1 2.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 3.1 PID P73PATHWAY p73 transcription factor network
0.1 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.5 15.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.9 7.7 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.5 9.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 3.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.5 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 4.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 2.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 4.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 3.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 2.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 3.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 3.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 4.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 14.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.2 2.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 0.6 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.2 1.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 1.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 5.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 1.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 1.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.2 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 2.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 13.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 2.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production