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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for figla

Z-value: 1.42

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Transcription factors associated with figla

Gene Symbol Gene ID Gene Info
ENSDARG00000087166 folliculogenesis specific bHLH transcription factor
ENSDARG00000115572 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
figladr11_v1_chr5_-_13848296_138482960.285.7e-03Click!

Activity profile of figla motif

Sorted Z-values of figla motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_30404096 25.45 ENSDART00000103475
anterior gradient 2
chr5_-_29531948 16.01 ENSDART00000098360
arrestin domain containing 1a
chr20_-_21672970 15.82 ENSDART00000133286
si:ch211-207i1.2
chr14_+_34514336 15.32 ENSDART00000024440
forkhead box I3b
chr3_+_36424055 14.97 ENSDART00000170318
si:ch1073-443f11.2
chr5_-_23696926 13.47 ENSDART00000021462
ring finger protein 128a
chr13_+_33606739 12.91 ENSDART00000026464
cofilin 1 (non-muscle), like
chr9_+_17309195 12.69 ENSDART00000048548
sciellin
chr22_-_17677947 12.50 ENSDART00000139911
tight junction protein 3
chr19_-_30403922 11.89 ENSDART00000181841
anterior gradient 2
chr17_+_26965351 11.68 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr3_+_49021079 11.65 ENSDART00000162012
zgc:163083
chr13_+_50375800 11.51 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr13_-_21672131 11.22 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr3_+_23221047 11.12 ENSDART00000009393
collagen, type I, alpha 1a
chr11_+_11504014 11.09 ENSDART00000104264
ENSDART00000134806
ENSDART00000132291
zgc:171226
chr21_+_30351256 11.01 ENSDART00000078341
forkhead box I3a
chr13_-_12581388 10.98 ENSDART00000079655
glutamyl aminopeptidase
chr22_+_11756040 10.93 ENSDART00000105808
keratin 97
chr16_-_39570832 10.78 ENSDART00000039832
transforming growth factor beta receptor 2b
chr8_+_6576940 10.63 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr8_-_14554785 10.53 ENSDART00000057645
quiescin Q6 sulfhydryl oxidase 1
chr9_-_9989660 10.53 ENSDART00000081463
UDP glucuronosyltransferase 1 family a, b
chr10_-_2942900 10.31 ENSDART00000002622
occludin a
chr24_+_35564668 10.19 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr23_-_29824146 9.74 ENSDART00000020616
zgc:194189
chr10_+_33171501 9.68 ENSDART00000159666
myosin, light chain 10, regulatory
chr4_-_8043839 9.55 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr10_-_25217347 9.50 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr22_+_26400519 9.46 ENSDART00000159839
ENSDART00000144585
calpain 8
chr7_+_49664174 9.30 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr14_-_33277743 9.28 ENSDART00000048130
START domain containing 14
chr6_-_8360918 9.19 ENSDART00000004716
acid phosphatase 5a, tartrate resistant
chr16_+_17715243 9.05 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
chr19_-_7110617 9.05 ENSDART00000104838
proteasome subunit beta 8A
chr11_-_28050559 9.03 ENSDART00000136859
endothelin converting enzyme 1
chr11_-_5865744 8.86 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr19_+_7636941 8.75 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr9_-_34396264 8.70 ENSDART00000045754
growth hormone regulated TBC protein 1b
chr6_+_11438972 8.69 ENSDART00000029314
collagen, type V, alpha 2b
chr4_+_5537101 8.68 ENSDART00000008692
si:dkey-14d8.7
chr7_+_58751504 8.56 ENSDART00000024185
zgc:56231
chr3_-_26204867 8.56 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr25_+_8356707 8.43 ENSDART00000153708
mucin 5.1, oligomeric mucus/gel-forming
chr16_+_34111919 8.23 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
transcription elongation factor A (SII), 3
chr3_+_42923275 8.16 ENSDART00000168228
transmembrane protein 184a
chr23_+_25305431 8.12 ENSDART00000143291
si:dkey-151g10.6
chr13_-_34683370 8.10 ENSDART00000113661
kinesin family member 16Bb
chr5_+_57924611 8.09 ENSDART00000050949
B-cell translocation gene 4
chr15_+_34963316 8.01 ENSDART00000153840
si:ch73-95l15.5
chr14_-_33278084 7.94 ENSDART00000132850
START domain containing 14
chr14_+_22297257 7.85 ENSDART00000113676
ATPase phospholipid transporting 10B
chr2_-_42628028 7.84 ENSDART00000179866
myosin X
chr16_-_42066523 7.62 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr4_+_5531583 7.62 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
chr12_-_23365737 7.61 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr16_+_19637384 7.61 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr6_+_23057311 7.57 ENSDART00000026448
envoplakin a
chr7_+_57088920 7.56 ENSDART00000024076
secretory carrier membrane protein 2, like
chr19_-_35035857 7.47 ENSDART00000103253
bone morphogenetic protein 8a
chr3_-_32965848 7.44 ENSDART00000050930
caspase 6, apoptosis-related cysteine peptidase
chr23_+_31815423 7.43 ENSDART00000075730
ENSDART00000075726
v-myb avian myeloblastosis viral oncogene homolog
chr7_+_57089354 7.38 ENSDART00000140702
secretory carrier membrane protein 2, like
chr6_-_607063 7.27 ENSDART00000189900
lectin, galactoside-binding, soluble, 2b
chr5_-_37900350 7.26 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr16_-_47381519 7.25 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr1_-_59104145 7.14 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr20_-_43743700 7.12 ENSDART00000100620
si:dkeyp-50f7.2
chr3_+_34121156 7.03 ENSDART00000174929
aldehyde dehydrogenase 3 family, member B1
chr21_+_11969603 7.02 ENSDART00000142247
ENSDART00000140652
motilin-like
chr2_+_15612755 6.99 ENSDART00000003035
amylase, alpha 2A (pancreatic)
chr7_-_38644560 6.91 ENSDART00000114934
six-cysteine containing astacin protease 3
chr21_+_11776328 6.83 ENSDART00000134469
ENSDART00000081646
glutaredoxin (thioltransferase)
chr7_+_6652967 6.80 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr15_-_29326254 6.73 ENSDART00000114492
si:dkey-52l18.4
chr15_-_39969988 6.67 ENSDART00000146054
ribosomal protein S5
chr7_+_31879649 6.63 ENSDART00000099789
myosin binding protein C, cardiac
chr7_+_7048245 6.60 ENSDART00000001649
actinin alpha 3b
chr24_-_2423791 6.55 ENSDART00000190402
ras responsive element binding protein 1a
chr18_+_36631923 6.53 ENSDART00000098980
zinc finger protein 296
chr19_-_10771558 6.48 ENSDART00000085165
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 2
chr5_+_6670945 6.33 ENSDART00000185686
paxillin a
chr7_+_6969909 6.24 ENSDART00000189886
actinin alpha 3b
chr7_-_35066457 6.24 ENSDART00000058067
zgc:112160
chr15_+_38299385 6.22 ENSDART00000142403
si:dkey-24p1.6
chr8_+_44358443 6.21 ENSDART00000189130
ENSDART00000189212

chr7_+_31879986 6.19 ENSDART00000138491
myosin binding protein C, cardiac
chr5_-_32338866 6.19 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr3_-_4612324 6.14 ENSDART00000101228
finTRIM family, member 50
chr18_+_45666489 6.05 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_-_29747702 6.05 ENSDART00000133225
ENSDART00000189670
secreted phosphoprotein 2
chr1_-_6085750 6.02 ENSDART00000138891
si:ch1073-345a8.1
chr8_-_30242706 6.01 ENSDART00000139864
ENSDART00000143809
zgc:162939
chr10_+_29850330 6.00 ENSDART00000168898
heat shock protein 8
chr16_-_26676685 5.98 ENSDART00000103431
epithelial splicing regulatory protein 1
chr12_+_30360184 5.91 ENSDART00000190718
si:ch211-225b10.3
chr5_-_38451082 5.90 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr18_+_8340886 5.89 ENSDART00000081132
carnitine palmitoyltransferase 1B (muscle)
chr12_-_28818720 5.88 ENSDART00000134453
ENSDART00000141727
proline rich 15-like b
chr4_-_8040436 5.84 ENSDART00000113033
si:ch211-240l19.6
chr2_+_9560740 5.83 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr3_+_34846201 5.76 ENSDART00000055263
integrin, alpha 3a
chr2_+_21000334 5.75 ENSDART00000062563
ENSDART00000147809
ras responsive element binding protein 1b
chr9_-_42989297 5.67 ENSDART00000126871
titin, tandem duplicate 2
chr15_+_38299563 5.66 ENSDART00000099375
si:dkey-24p1.6
chr8_-_3312384 5.62 ENSDART00000035965
fucosyltransferase 9b
chr7_+_52122224 5.54 ENSDART00000174268
cytochrome P450, family 2, subfamily X, polypeptide 12
chr10_+_29849977 5.54 ENSDART00000180242
heat shock protein 8
chr9_+_159720 5.48 ENSDART00000166215
claudin 10-like 2
chr4_+_72797711 5.42 ENSDART00000190934
ENSDART00000163236
myelin regulatory factor-like
chr8_+_29593986 5.38 ENSDART00000077642
atonal bHLH transcription factor 1a
chr8_-_43923788 5.37 ENSDART00000146152
adhesion G protein-coupled receptor D1
chr7_-_38644287 5.34 ENSDART00000182307
six-cysteine containing astacin protease 3
chr25_-_17395315 5.31 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr6_+_54711306 5.31 ENSDART00000074605
plakophilin 1b
chr5_-_66301142 5.31 ENSDART00000067541
prolactin receptor b
chr19_+_2590182 5.28 ENSDART00000162293
si:ch73-345f18.3
chr1_+_36665555 5.28 ENSDART00000128557
ENSDART00000010632
endothelin receptor type Aa
chr8_+_40477264 5.22 ENSDART00000085559
glucokinase (hexokinase 4)
chr9_-_23922778 5.17 ENSDART00000135769
collagen, type VI, alpha 3
chr5_-_29152457 5.05 ENSDART00000078469
NADPH oxidase activator 1
chr22_+_22021936 5.05 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr21_-_34261677 4.96 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr25_-_17587785 4.93 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr8_+_45334255 4.92 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr19_-_27542433 4.82 ENSDART00000136414
si:ch211-152p11.4
chr14_+_2487672 4.82 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr13_+_11876437 4.81 ENSDART00000179753
tripartite motif containing 8a
chr2_+_27855346 4.80 ENSDART00000175159
ENSDART00000192645
bucky ball
chr1_-_53468160 4.78 ENSDART00000143349
zgc:66455
chr4_-_75175407 4.74 ENSDART00000180125

chr4_-_13614797 4.70 ENSDART00000138366
ENSDART00000165212
interferon regulatory factor 5
chr9_-_34296406 4.63 ENSDART00000125451
immunoglobulin-like domain containing receptor 2
chr5_-_22052852 4.61 ENSDART00000002938
myotubularin related protein 8
chr11_+_31285127 4.61 ENSDART00000160154
si:dkey-238i5.2
chr17_+_8799451 4.59 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr14_-_32631013 4.56 ENSDART00000176815
ATPase phospholipid transporting 11C
chr15_+_36096689 4.51 ENSDART00000049849
collagen, type IV, alpha 3
chr5_-_69212184 4.48 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr6_-_10788065 4.46 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr6_+_42338309 4.46 ENSDART00000015277
glutathione peroxidase 1b
chr21_+_15375785 4.44 ENSDART00000147666
si:dkey-11o15.8
chr2_+_27855102 4.44 ENSDART00000150330
bucky ball
chr5_+_28271412 4.41 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr18_-_37241080 4.41 ENSDART00000126421
ENSDART00000078064
SIX homeobox 9
chr22_-_5171829 4.36 ENSDART00000140313
tumor necrosis factor, alpha-induced protein 8-like 1
chr12_-_46145635 4.36 ENSDART00000074682
zgc:153932
chr6_+_56141852 4.35 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr21_-_45882643 4.34 ENSDART00000168703
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr4_-_22363709 4.34 ENSDART00000037670
origin recognition complex, subunit 5
chr3_+_53240562 4.30 ENSDART00000031234
syntaxin binding protein 2
chr9_-_42873700 4.22 ENSDART00000125953
titin, tandem duplicate 1
chr15_+_33989181 4.21 ENSDART00000169487
von Willebrand factor D and EGF domains
chr9_-_40014339 4.20 ENSDART00000166918
si:zfos-1425h8.1
chr1_-_18752981 4.19 ENSDART00000188146
ENSDART00000193094
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr23_-_30041065 4.19 ENSDART00000131209
ENSDART00000127192
coiled-coil domain containing 187
chr15_-_34878388 4.16 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr17_+_5976683 4.16 ENSDART00000110276
zgc:194275
chr7_+_67699178 4.15 ENSDART00000160086
zgc:162592
chr7_+_69841017 4.13 ENSDART00000169107

chr5_+_58679071 4.10 ENSDART00000019561
zgc:171734
chr13_+_24584401 4.09 ENSDART00000057599
fucose mutarotase
chr10_-_1961930 4.07 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr23_+_18722915 4.07 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr6_+_50452699 4.01 ENSDART00000115049
myelocytomatosis oncogene homolog
chr6_-_52348562 3.99 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr18_+_13248956 3.99 ENSDART00000080709
phospholipase C, gamma 2
chr20_+_46371458 3.97 ENSDART00000152912
adhesion G protein-coupled receptor G11
chr18_+_2228737 3.95 ENSDART00000165301
RAB27A, member RAS oncogene family
chr6_+_103361 3.95 ENSDART00000151899
low density lipoprotein receptor b
chr15_+_29024895 3.91 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr12_-_4301234 3.91 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr23_-_44965582 3.89 ENSDART00000163367
transferrin receptor 2
chr14_-_41678357 3.89 ENSDART00000185925
fibroblast growth factor receptor like 1b
chr10_-_24784446 3.87 ENSDART00000140877
si:ch1073-15f19.2
chr15_-_5624361 3.86 ENSDART00000176446
ENSDART00000114410
WD repeat domain 62
chr1_+_1915967 3.84 ENSDART00000131463
si:ch211-132g1.1
chr2_-_17114852 3.83 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr18_-_44316920 3.82 ENSDART00000098599
si:ch211-151h10.2
chr22_+_20427170 3.81 ENSDART00000136744
forkhead box Q2
chr3_+_14641962 3.81 ENSDART00000091070
zgc:158403
chr2_+_43204919 3.81 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr22_-_10470663 3.80 ENSDART00000143352
osteomodulin
chr11_-_11336986 3.78 ENSDART00000016677
zgc:77929
chr16_-_50229193 3.77 ENSDART00000161782
ENSDART00000010081
electron-transfer-flavoprotein, beta polypeptide
chr22_-_10891213 3.69 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr12_-_16990896 3.67 ENSDART00000152402
interferon-induced protein with tetratricopeptide repeats 12
chr17_+_132555 3.66 ENSDART00000158159
zgc:77287
chr15_+_24572926 3.64 ENSDART00000155636
ENSDART00000187800
dehydrogenase/reductase (SDR family) member 13b
chr23_-_45501177 3.61 ENSDART00000150103
collagen type XXIV alpha 1
chr13_+_31716820 3.59 ENSDART00000034745
protein kinase C, eta, a
chr18_+_21061216 3.57 ENSDART00000141739
family with sequence similarity 169, member B
chr12_+_30360579 3.56 ENSDART00000152900
si:ch211-225b10.3
chr3_-_8265158 3.55 ENSDART00000171310
cytochrome P450, family 2, subfamily K, polypeptide 6
chr7_+_20471315 3.54 ENSDART00000173714
si:dkey-19b23.13
chr7_-_50367326 3.51 ENSDART00000141926
protein regulator of cytokinesis 1b
chr17_+_8799661 3.51 ENSDART00000105326
tonsoku-like, DNA repair protein
chr25_+_9003230 3.51 ENSDART00000180330
ENSDART00000142917
recombination activating gene 1
chr7_+_67699009 3.42 ENSDART00000192810
zgc:162592
chr21_-_39931285 3.40 ENSDART00000180010
ENSDART00000024407
transmembrane and immunoglobulin domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 26.3 GO:0009957 epidermal cell fate specification(GO:0009957)
4.3 12.9 GO:0030043 actin filament fragmentation(GO:0030043)
3.7 37.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
3.0 8.9 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.8 11.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
2.6 12.8 GO:0003210 cardiac atrium formation(GO:0003210)
1.9 11.5 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
1.9 5.6 GO:0090008 hypoblast development(GO:0090008)
1.8 5.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.6 6.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
1.5 9.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
1.4 12.5 GO:0030104 water homeostasis(GO:0030104)
1.3 4.0 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
1.3 5.3 GO:0038161 prolactin signaling pathway(GO:0038161)
1.2 7.4 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
1.2 3.5 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
1.0 3.9 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
1.0 2.9 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
1.0 3.8 GO:0051660 establishment of centrosome localization(GO:0051660)
0.9 1.8 GO:0065001 specification of axis polarity(GO:0065001)
0.9 5.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.9 2.6 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.9 11.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 2.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.8 9.2 GO:0045453 bone resorption(GO:0045453)
0.8 6.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.8 9.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.8 2.3 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.8 11.7 GO:0060325 face morphogenesis(GO:0060325)
0.8 6.2 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.8 5.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.8 12.8 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 4.5 GO:0010269 response to selenium ion(GO:0010269)
0.7 3.0 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.7 4.4 GO:0070254 mucus secretion(GO:0070254)
0.7 4.1 GO:0006004 fucose metabolic process(GO:0006004)
0.7 5.3 GO:0090594 inflammatory response to wounding(GO:0090594)
0.7 14.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.7 3.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.6 3.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.6 3.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.6 4.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 5.1 GO:0042554 superoxide anion generation(GO:0042554)
0.6 5.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6 9.9 GO:0048769 sarcomerogenesis(GO:0048769)
0.6 3.1 GO:1901207 regulation of heart looping(GO:1901207)
0.6 6.0 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.6 9.0 GO:0016486 peptide hormone processing(GO:0016486)
0.6 3.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.6 10.2 GO:0008354 germ cell migration(GO:0008354)
0.6 6.4 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.6 2.9 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.6 2.3 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.6 2.8 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 2.2 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.5 11.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 3.7 GO:0090497 mesenchymal cell migration(GO:0090497)
0.5 6.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.5 5.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.5 5.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.5 4.3 GO:0046849 bone remodeling(GO:0046849)
0.4 9.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.4 16.3 GO:0030199 collagen fibril organization(GO:0030199)
0.4 8.1 GO:0031297 replication fork processing(GO:0031297)
0.4 3.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.4 6.3 GO:0061055 myotome development(GO:0061055)
0.4 2.0 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.4 1.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4 2.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 11.0 GO:0043171 peptide catabolic process(GO:0043171)
0.4 17.4 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.4 12.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.4 0.7 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 2.4 GO:0061511 centriole elongation(GO:0061511)
0.3 3.8 GO:0033151 V(D)J recombination(GO:0033151)
0.3 2.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.3 4.4 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.3 5.7 GO:0009395 phospholipid catabolic process(GO:0009395)
0.3 8.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.3 5.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.3 2.5 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3 2.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 1.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.3 5.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 3.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 14.3 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.3 6.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 3.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.3 2.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 9.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 3.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 2.6 GO:0007608 sensory perception of smell(GO:0007608)
0.2 2.5 GO:0043114 regulation of vascular permeability(GO:0043114)
0.2 1.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 9.5 GO:0007586 digestion(GO:0007586)
0.2 9.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 4.0 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.2 3.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 2.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.2 2.9 GO:0030183 B cell differentiation(GO:0030183)
0.2 9.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.2 1.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 4.3 GO:0006270 DNA replication initiation(GO:0006270)
0.2 4.2 GO:0007520 myoblast fusion(GO:0007520)
0.2 4.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 6.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.2 2.4 GO:0070527 platelet aggregation(GO:0070527)
0.2 3.8 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.2 3.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.2 2.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 7.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 2.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 11.1 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 2.9 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.1 2.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 8.4 GO:0051607 defense response to virus(GO:0051607)
0.1 8.1 GO:0006414 translational elongation(GO:0006414)
0.1 1.7 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.2 GO:0042098 T cell proliferation(GO:0042098)
0.1 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.9 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 5.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.1 2.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0060092 inhibitory postsynaptic potential(GO:0060080) regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 4.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 3.2 GO:0048599 oocyte development(GO:0048599)
0.1 3.1 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 1.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.7 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 7.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 2.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 19.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 5.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 7.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 10.4 GO:0006457 protein folding(GO:0006457)
0.1 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 10.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 5.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 2.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 1.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 2.0 GO:0030048 actin filament-based movement(GO:0030048)
0.1 5.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 4.6 GO:0007492 endoderm development(GO:0007492)
0.1 1.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 3.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 5.9 GO:0008544 epidermis development(GO:0008544)
0.1 6.0 GO:0045765 regulation of angiogenesis(GO:0045765)
0.1 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 2.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 16.7 GO:0042127 regulation of cell proliferation(GO:0042127)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 4.2 GO:0021782 glial cell development(GO:0021782)
0.0 1.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.5 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 1.3 GO:0001707 formation of primary germ layer(GO:0001704) mesoderm formation(GO:0001707)
0.0 5.0 GO:0051216 cartilage development(GO:0051216)
0.0 0.9 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 2.0 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.0 2.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.4 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 1.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.4 GO:0061515 myeloid cell development(GO:0061515)
0.0 2.8 GO:0007623 circadian rhythm(GO:0007623)
0.0 1.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.2 GO:0031638 zymogen activation(GO:0031638)
0.0 2.0 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.4 GO:0051170 nuclear import(GO:0051170)
0.0 0.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 3.3 GO:0007601 visual perception(GO:0007601)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 6.6 GO:0006897 endocytosis(GO:0006897)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 11.1 GO:0015031 protein transport(GO:0015031)
0.0 0.8 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 1.4 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.2 GO:0060972 left/right pattern formation(GO:0060972)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.7 GO:0005588 collagen type V trimer(GO:0005588)
1.2 3.6 GO:0005592 collagen type XI trimer(GO:0005592)
1.2 8.1 GO:0005662 DNA replication factor A complex(GO:0005662)
1.2 9.2 GO:0032019 mitochondrial cloud(GO:0032019)
1.1 4.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.0 19.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.9 3.8 GO:0097519 DNA recombinase complex(GO:0097519)
0.8 3.2 GO:0043073 germ cell nucleus(GO:0043073)
0.8 6.0 GO:0071546 pi-body(GO:0071546)
0.7 6.5 GO:0031526 brush border membrane(GO:0031526)
0.7 8.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.7 14.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.6 5.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 3.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.5 6.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.5 3.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 1.2 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.4 46.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.4 9.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 4.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 9.0 GO:0005839 proteasome core complex(GO:0005839)
0.3 5.3 GO:0030057 desmosome(GO:0030057)
0.3 2.8 GO:0005903 brush border(GO:0005903)
0.3 23.0 GO:0005581 collagen trimer(GO:0005581)
0.2 3.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 3.2 GO:0042555 MCM complex(GO:0042555)
0.2 2.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 2.0 GO:0061617 MICOS complex(GO:0061617)
0.2 1.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 4.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 10.5 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 9.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 12.7 GO:0030141 secretory granule(GO:0030141)
0.1 6.3 GO:0005657 replication fork(GO:0005657)
0.1 6.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 4.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 2.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 11.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 11.6 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 10.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.7 GO:0016342 catenin complex(GO:0016342)
0.1 1.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 1.7 GO:0097546 ciliary base(GO:0097546)
0.1 1.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 10.8 GO:0016459 myosin complex(GO:0016459)
0.1 28.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 8.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 16.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 5.7 GO:0000786 nucleosome(GO:0000786)
0.1 6.3 GO:0005770 late endosome(GO:0005770)
0.1 2.5 GO:0031941 filamentous actin(GO:0031941)
0.1 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 10.1 GO:0000785 chromatin(GO:0000785)
0.0 5.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 3.4 GO:0005871 kinesin complex(GO:0005871)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 61.7 GO:0005576 extracellular region(GO:0005576)
0.0 5.6 GO:0005764 lysosome(GO:0005764)
0.0 0.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 6.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 8.3 GO:0005743 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 3.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 10.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
3.2 16.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
1.8 10.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.4 4.1 GO:0042806 fucose binding(GO:0042806)
1.3 5.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.3 7.6 GO:0019215 intermediate filament binding(GO:0019215)
1.3 6.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.2 7.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.2 12.8 GO:0032036 myosin heavy chain binding(GO:0032036)
1.1 9.2 GO:0003993 acid phosphatase activity(GO:0003993)
1.1 4.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
1.0 4.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.0 3.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.9 7.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 3.8 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.9 5.2 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.8 5.9 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.8 11.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.8 6.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.8 6.0 GO:0034584 piRNA binding(GO:0034584)
0.8 5.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 12.8 GO:0032190 acrosin binding(GO:0032190)
0.7 7.5 GO:0070700 BMP receptor binding(GO:0070700)
0.7 7.3 GO:0016936 galactoside binding(GO:0016936)
0.7 7.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.7 4.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.6 3.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.6 4.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 6.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.6 11.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.6 9.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6 5.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6 5.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.6 9.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.5 2.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 11.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 9.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 1.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 4.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 2.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.4 13.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 3.3 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.4 11.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 3.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 8.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.4 4.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 11.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 3.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 2.9 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.3 4.1 GO:0070696 receptor serine/threonine kinase binding(GO:0033612) transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.3 3.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 10.6 GO:0009055 electron carrier activity(GO:0009055)
0.3 36.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 17.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.3 2.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 0.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 35.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.3 3.1 GO:0043495 protein anchor(GO:0043495)
0.2 4.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 3.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 2.4 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 0.9 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 4.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 4.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 8.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 10.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 9.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 11.2 GO:0003823 antigen binding(GO:0003823)
0.2 27.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 23.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.8 GO:0005112 Notch binding(GO:0005112)
0.1 4.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 3.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 6.7 GO:0019843 rRNA binding(GO:0019843)
0.1 1.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.7 GO:0051117 ATPase binding(GO:0051117)
0.1 8.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.5 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 4.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 2.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 4.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 9.2 GO:0045296 cadherin binding(GO:0045296)
0.1 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 3.3 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 16.2 GO:0003774 motor activity(GO:0003774)
0.1 13.2 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 7.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 4.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 12.4 GO:0000287 magnesium ion binding(GO:0000287)
0.1 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 1.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 2.7 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 3.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 8.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 23.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 5.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 5.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 7.6 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.6 GO:0016597 amino acid binding(GO:0016597)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 40.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 13.3 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 5.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.3 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 PID CONE PATHWAY Visual signal transduction: Cones
0.5 22.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 16.6 NABA COLLAGENS Genes encoding collagen proteins
0.4 26.7 PID CMYB PATHWAY C-MYB transcription factor network
0.4 3.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 8.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 2.9 PID IL1 PATHWAY IL1-mediated signaling events
0.2 3.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 5.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 7.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 6.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 2.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 5.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 7.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 5.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.0 6.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.9 8.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 11.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.6 6.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 4.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 5.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 5.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 3.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 16.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 2.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 6.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 6.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 2.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 4.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 2.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 3.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 12.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 4.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 7.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 4.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 18.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 4.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 8.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 3.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 8.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane