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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for etv7
Z-value: 0.89
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Transcription factors associated with etv7
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| etv7 | dr11_v1_chr23_-_5101847_5101847 | 0.62 | 3.2e-11 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_45001842 Show fit | 7.06 |
ENSDART00000037797
|
sulfotransferase family 2, cytosolic sulfotransferase 3 |
|
| chr11_-_18254 Show fit | 6.98 |
ENSDART00000167814
|
proline rich 13 |
|
| chr11_-_18449 Show fit | 6.66 |
ENSDART00000172050
|
proline rich 13 |
|
| chr6_+_52212927 Show fit | 6.12 |
ENSDART00000143458
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a |
|
| chr6_+_52212574 Show fit | 5.15 |
ENSDART00000025940
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a |
|
| chr22_-_24297510 Show fit | 4.12 |
ENSDART00000163297
|
si:ch211-117l17.6 |
|
| chr6_+_112579 Show fit | 4.08 |
ENSDART00000034505
|
adaptor-related protein complex 1, mu 2 subunit |
|
| chr18_-_50799510 Show fit | 4.07 |
ENSDART00000174373
|
transaldolase 1 |
|
| chr5_-_38777852 Show fit | 3.97 |
ENSDART00000131603
|
si:dkey-58f10.4 |
|
| chr8_-_45430817 Show fit | 3.89 |
ENSDART00000150067
ENSDART00000112394 |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b |
Network of associatons between targets according to the STRING database.
First level regulatory network of etv7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.3 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.3 | 7.4 | GO:1901654 | response to ketone(GO:1901654) |
| 0.0 | 5.3 | GO:0045087 | innate immune response(GO:0045087) |
| 0.5 | 4.6 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.6 | 4.3 | GO:0031048 | chromatin silencing by small RNA(GO:0031048) |
| 0.8 | 4.1 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.4 | 3.9 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 3.8 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.0 | 3.3 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 0.4 | 3.2 | GO:0060036 | notochord cell vacuolation(GO:0060036) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 5.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 4.7 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.6 | 4.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 4.4 | GO:0016604 | nuclear body(GO:0016604) |
| 0.1 | 4.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.3 | 3.9 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 3.5 | GO:0030880 | RNA polymerase complex(GO:0030880) |
| 0.2 | 2.9 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.1 | 2.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.4 | 5.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 5.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 4.7 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 4.5 | GO:0000989 | transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712) |
| 0.7 | 4.1 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 0.2 | 4.1 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 4.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.2 | 3.9 | GO:0070122 | isopeptidase activity(GO:0070122) |
| 0.0 | 3.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 3.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 3.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 2.3 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 2.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.6 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 1.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.5 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 1.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.0 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.5 | 4.6 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 4.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.4 | 4.1 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 4.1 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.0 | 2.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.7 | 2.6 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 2.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 2.4 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.5 | 2.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |