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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for ehf
Z-value: 1.21
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Transcription factors associated with ehf
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ehf | dr11_v1_chr25_+_10416583_10416583 | 0.46 | 2.8e-06 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_45177373 Show fit | 9.05 |
ENSDART00000143142
ENSDART00000034549 |
zgc:111983 |
|
| chr16_-_45001842 Show fit | 6.49 |
ENSDART00000037797
|
sulfotransferase family 2, cytosolic sulfotransferase 3 |
|
| chr7_+_45975537 Show fit | 6.20 |
ENSDART00000170253
|
pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
|
| chr2_+_20539402 Show fit | 5.21 |
ENSDART00000129585
|
si:ch73-14h1.2 |
|
| chr5_-_30615901 Show fit | 5.17 |
ENSDART00000147769
|
si:ch211-117m20.5 |
|
| chr3_+_27713610 Show fit | 4.93 |
ENSDART00000019004
|
Rho GDP dissociation inhibitor (GDI) gamma |
|
| chr14_+_28438947 Show fit | 4.85 |
ENSDART00000006489
|
acyl-CoA synthetase long chain family member 4a |
|
| chr21_+_25765734 Show fit | 4.58 |
ENSDART00000021664
|
claudin b |
|
| chr20_-_37629084 Show fit | 4.43 |
ENSDART00000141734
|
human immunodeficiency virus type I enhancer binding protein 2a |
|
| chr7_-_19923249 Show fit | 4.32 |
ENSDART00000078694
|
zgc:110591 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ehf
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.2 | GO:0006886 | intracellular protein transport(GO:0006886) |
| 0.2 | 8.9 | GO:0043297 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
| 0.0 | 8.5 | GO:0072657 | protein localization to membrane(GO:0072657) |
| 1.2 | 8.3 | GO:0016137 | glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139) |
| 0.3 | 8.1 | GO:0051923 | sulfation(GO:0051923) |
| 0.2 | 6.8 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
| 0.1 | 6.5 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 1.1 | 6.3 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.1 | 5.9 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 5.8 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.0 | GO:0005764 | lysosome(GO:0005764) |
| 0.0 | 12.8 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 8.8 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 8.7 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 7.8 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 7.1 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 6.8 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 6.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.4 | 5.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 5.8 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.6 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 8.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 7.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.8 | 7.0 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.0 | 7.0 | GO:0020037 | heme binding(GO:0020037) |
| 0.1 | 6.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.6 | 6.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 1.5 | 5.9 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 1.9 | 5.8 | GO:0015928 | alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928) |
| 0.1 | 5.1 | GO:0008146 | sulfotransferase activity(GO:0008146) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.3 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 4.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 4.7 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 4.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.2 | 4.6 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.7 | 4.4 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 3.7 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.2 | 3.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.2 | 3.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.2 | 3.2 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.2 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.1 | 6.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.7 | 6.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.6 | 4.8 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.3 | 4.3 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 4.3 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.2 | 3.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.4 | 3.5 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.2 | 3.1 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.1 | 2.9 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |