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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ehf

Z-value: 1.21

Motif logo

Transcription factors associated with ehf

Gene Symbol Gene ID Gene Info
ENSDARG00000052115 ets homologous factor
ENSDARG00000112589 ets homologous factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ehfdr11_v1_chr25_+_10416583_104165830.462.8e-06Click!

Activity profile of ehf motif

Sorted Z-values of ehf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_45177373 9.05 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr16_-_45001842 6.49 ENSDART00000037797
sulfotransferase family 2, cytosolic sulfotransferase 3
chr7_+_45975537 6.20 ENSDART00000170253
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr2_+_20539402 5.21 ENSDART00000129585
si:ch73-14h1.2
chr5_-_30615901 5.17 ENSDART00000147769
si:ch211-117m20.5
chr3_+_27713610 4.93 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr14_+_28438947 4.85 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr21_+_25765734 4.58 ENSDART00000021664
claudin b
chr20_-_37629084 4.43 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr7_-_19923249 4.32 ENSDART00000078694
zgc:110591
chr15_-_2652640 4.30 ENSDART00000146094
claudin f
chr7_+_38762043 4.30 ENSDART00000036461
Rho GTPase activating protein 1
chr15_-_29598679 4.20 ENSDART00000155153
si:ch211-207n23.2
chr25_-_37338048 4.09 ENSDART00000073439
tripartite motif containing 44
chr23_+_20803270 4.08 ENSDART00000097381
zgc:154075
chr17_-_13026634 4.03 ENSDART00000113713
family with sequence similarity 177, member A1
chr3_+_36424055 4.02 ENSDART00000170318
si:ch1073-443f11.2
chr18_-_48500545 4.00 ENSDART00000058989
ENSDART00000098450
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 5
chr24_+_35911020 3.98 ENSDART00000088480
ATP-binding cassette, sub-family D (ALD), member 4
chr1_-_45157243 3.95 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr20_-_5369105 3.84 ENSDART00000114316
serine palmitoyltransferase, long chain base subunit 2b
chr25_+_7784582 3.84 ENSDART00000155016
diacylglycerol kinase, zeta b
chr6_-_49063085 3.84 ENSDART00000156124
si:ch211-105j21.9
chr5_-_34616599 3.83 ENSDART00000050271
ENSDART00000097975
hexosaminidase B (beta polypeptide)
chr20_+_22666548 3.72 ENSDART00000147520
ligand of numb-protein X 1
chr15_-_23793641 3.71 ENSDART00000122891
transmembrane protein 97
chr1_+_40237276 3.70 ENSDART00000037553
fatty acid amide hydrolase 2a
chr3_-_5067585 3.69 ENSDART00000169609
thyrotrophic embryonic factor b
chr23_-_31969786 3.69 ENSDART00000134550
ORMDL sphingolipid biosynthesis regulator 2
chr5_+_28271412 3.63 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr1_-_69444 3.57 ENSDART00000166954
si:zfos-1011f11.1
chr19_-_1871415 3.51 ENSDART00000004585
CLPTM1-like
chr6_-_40768654 3.42 ENSDART00000184668
ENSDART00000146470
actin related protein 2/3 complex, subunit 4
chr2_-_27609189 3.39 ENSDART00000040555
LYN proto-oncogene, Src family tyrosine kinase
chr9_+_9502610 3.34 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr5_+_63390315 3.33 ENSDART00000124616
RAB14, member RAS oncogene family
chr19_-_32500373 3.29 ENSDART00000052104
alpha-L-fucosidase 1, tandem duplicate 1
chr20_-_30900947 3.24 ENSDART00000153419
ENSDART00000062536
heme binding protein 2
chr22_-_16042243 3.21 ENSDART00000062633
sphingosine-1-phosphate receptor 1
chr13_+_27316934 3.21 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr15_+_36054864 3.20 ENSDART00000156697
collagen, type IV, alpha 3
chr25_+_22216723 3.20 ENSDART00000051291
hexosaminidase A (alpha polypeptide)
chr8_+_19356072 3.19 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr13_+_27316632 3.17 ENSDART00000016121
eukaryotic translation elongation factor 1 alpha 1a
chr19_-_340347 3.15 ENSDART00000139924
golgi phosphoprotein 3-like
chr3_-_36440705 3.15 ENSDART00000162875
rogdi homolog (Drosophila)
chr17_+_25331576 3.11 ENSDART00000157309
transmembrane protein 54a
chr9_-_33081781 3.09 ENSDART00000165748
zgc:172053
chr24_-_6078222 3.08 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr4_-_12978925 3.07 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr18_+_22994113 3.07 ENSDART00000171871
core-binding factor, beta subunit
chr3_+_34120191 3.06 ENSDART00000020017
ENSDART00000151700
aldehyde dehydrogenase 3 family, member B1
chr9_-_33081978 3.05 ENSDART00000100918
zgc:172053
chr3_+_24190207 3.03 ENSDART00000034762
proline rich 15-like a
chr3_+_46479705 2.98 ENSDART00000181564
tyrosine kinase 2
chr15_-_28618502 2.94 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr2_+_31838442 2.93 ENSDART00000066789
STARD3 N-terminal like
chr23_+_20669149 2.93 ENSDART00000138936
Rho guanine nucleotide exchange factor (GEF) 3, like
chr1_+_33558555 2.92 ENSDART00000018472
charged multivesicular body protein 2Bb
chr5_+_21931124 2.92 ENSDART00000137627
si:ch73-92i20.1
chr19_-_340641 2.90 ENSDART00000183848
golgi phosphoprotein 3-like
chr10_+_26667475 2.90 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr19_+_33093395 2.90 ENSDART00000019459
family with sequence similarity 91, member A1
chr19_-_20430892 2.89 ENSDART00000111409
TBC1 domain family, member 5
chr3_+_36616713 2.87 ENSDART00000158284
pyridoxal-dependent decarboxylase domain containing 1
chr3_+_26223376 2.87 ENSDART00000128284
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr1_+_51386649 2.86 ENSDART00000152289
autophagy related 4D, cysteine peptidase a
chr24_+_20916751 2.84 ENSDART00000043193
cystatin 14a, tandem duplicate 1
chr5_-_31712399 2.82 ENSDART00000141328
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr14_+_30272891 2.82 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr22_+_10215558 2.81 ENSDART00000063274
potassium channel tetramerization domain containing 6a
chr18_+_21071023 2.81 ENSDART00000100778
actin related protein 2/3 complex inhibitor
chr16_-_31756859 2.78 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr17_-_6508406 2.77 ENSDART00000002778
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr14_+_31865099 2.77 ENSDART00000189124
transmembrane 9 superfamily protein member 5
chr24_+_17256793 2.76 ENSDART00000066764
COMM domain containing 3
chr1_-_8020589 2.74 ENSDART00000143881
si:dkeyp-9d4.2
chr20_-_34127415 2.71 ENSDART00000010028
prostaglandin-endoperoxide synthase 2b
chr5_+_23024033 2.71 ENSDART00000171199
chromatin modifying protein 1B
chr17_-_50311009 2.69 ENSDART00000153653
si:ch73-50f9.4
chr14_+_33427837 2.68 ENSDART00000105687
zinc finger and BTB domain containing 33
chr5_-_30516646 2.67 ENSDART00000014666
archain 1a
chr7_-_58178980 2.67 ENSDART00000073635
neutral sphingomyelinase (N-SMase) activation associated factor
chr6_+_19689464 2.65 ENSDART00000164960
syntaxin 8
chr17_-_50010121 2.64 ENSDART00000122747
transmembrane protein 30Aa
chr19_-_15420678 2.62 ENSDART00000151454
ENSDART00000027697
serine incorporator 2
chr2_-_47620806 2.59 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr20_-_3238110 2.58 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr20_+_35282682 2.56 ENSDART00000187199
family with sequence similarity 49, member A
chr11_+_8129536 2.56 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr24_+_9590188 2.55 ENSDART00000137092
si:dkey-96n2.1
chr19_-_32493866 2.55 ENSDART00000052090
alpha-L-fucosidase 1, tandem duplicate 2
chr16_-_25233515 2.55 ENSDART00000058943
zgc:110182
chr25_+_34749812 2.55 ENSDART00000185712
WW domain containing E3 ubiquitin protein ligase 2
chr20_-_14462995 2.53 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr13_+_24402406 2.52 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr6_+_49095646 2.51 ENSDART00000103385
solute carrier family 25, member 55a
chr14_+_31865324 2.51 ENSDART00000039880
transmembrane 9 superfamily protein member 5
chr5_+_22459087 2.50 ENSDART00000134781

chr23_+_32021803 2.49 ENSDART00000012963
trafficking protein particle complex 6b
chr6_+_18251140 2.48 ENSDART00000169752
coiled-coil domain containing 40
chr10_+_25369254 2.48 ENSDART00000164375
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr4_-_22311610 2.47 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr14_+_24277556 2.47 ENSDART00000122660
heterogeneous nuclear ribonucleoprotein A0a
chr15_+_7064819 2.44 ENSDART00000155268
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr1_+_12763461 2.44 ENSDART00000159226
ENSDART00000180121
protocadherin 10a
chr2_+_43920461 2.42 ENSDART00000123673
si:ch211-195h23.3
chr15_-_29598444 2.41 ENSDART00000154847
si:ch211-207n23.2
chr22_-_8306743 2.38 ENSDART00000123982

chr6_+_25215944 2.38 ENSDART00000165456
si:ch73-97h19.2
chr21_+_13908858 2.38 ENSDART00000148199
syntaxin binding protein 1a
chr8_-_17987547 2.37 ENSDART00000112699
ENSDART00000061747
fucose-1-phosphate guanylyltransferase
chr24_-_8409641 2.34 ENSDART00000149662
ENSDART00000149025
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr7_-_48805181 2.31 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr8_-_31107537 2.30 ENSDART00000098925
vestigial like 4 like
chr17_-_20218357 2.30 ENSDART00000155990
ENSDART00000155632
ENSDART00000156540
ENSDART00000063523
O-6-methylguanine-DNA methyltransferase
chr13_-_24311628 2.29 ENSDART00000004420
RAB4a, member RAS oncogene family
chr25_-_25575717 2.29 ENSDART00000067138
hypermethylated in cancer 1 like
chr8_+_52515188 2.28 ENSDART00000163668
si:ch1073-392o20.2
chr1_+_34685405 2.28 ENSDART00000037986
ENSDART00000166007
GPALPP motifs containing 1
chr19_+_40350468 2.28 ENSDART00000087444
HEPACAM family member 2
chr16_+_43368572 2.26 ENSDART00000032778
ENSDART00000193897
ring finger protein 144B
chr5_+_25084385 2.26 ENSDART00000134526
ENSDART00000111863
PAXX, non-homologous end joining factor
chr5_-_31470426 2.25 ENSDART00000002866
ENSDART00000181225
purinergic receptor P2X, ligand-gated ion channel, 1
chr8_-_39838660 2.25 ENSDART00000139266
finTRIM family, member 98
chr22_+_5687615 2.23 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr13_+_34689663 2.23 ENSDART00000133661
taspase, threonine aspartase, 1
chr5_+_19867794 2.21 ENSDART00000051614
trichoplein, keratin filament binding
chr21_+_21743599 2.20 ENSDART00000101700
polymerase (DNA-directed), delta 3, accessory subunit
chr6_-_41085692 2.17 ENSDART00000181463
serine/arginine-rich splicing factor 3a
chr22_+_17399124 2.12 ENSDART00000145769
RAB GTPase activating protein 1-like
chr25_-_35182347 2.10 ENSDART00000115210
anoctamin 9a
chr21_+_5508167 2.09 ENSDART00000157702
lymphocyte antigen 6 family member M4
chr2_+_47471943 2.09 ENSDART00000141974
acyl-CoA synthetase long chain family member 3b
chr13_-_32626247 2.06 ENSDART00000100663
WD repeat domain 35
chr13_-_22961605 2.06 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr24_-_10897511 2.06 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
family with sequence similarity 49, member Bb
chr24_-_24271629 2.05 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr21_-_2173300 2.04 ENSDART00000172276
zgc:163077
chr11_+_11719575 2.04 ENSDART00000003891
junction plakoglobin a
chr15_+_41919484 2.04 ENSDART00000099821
ENSDART00000146246
NACHT, LRR and PYD domains-containing protein 16
chr19_-_27006764 2.02 ENSDART00000089540
SAC1 like phosphatidylinositide phosphatase a
chr14_+_13453130 2.01 ENSDART00000054849
plastin 3 (T isoform)
chr2_-_43135700 2.01 ENSDART00000098284
finTRIM family, member 14
chr13_-_25408387 2.00 ENSDART00000002741
inositol 1,4,5-trisphosphate receptor interacting protein
chr12_+_31422557 2.00 ENSDART00000153179
zinc finger, DHHC-type containing 6
chr14_-_30897177 1.99 ENSDART00000087918
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr6_-_21988375 1.99 ENSDART00000161257
plexin b1b
chr7_-_8022741 1.99 ENSDART00000172841
si:ch211-163c2.1
chr7_+_48805534 1.98 ENSDART00000145375
ENSDART00000148744
carnitine palmitoyltransferase 1Aa (liver)
chr21_-_35419486 1.98 ENSDART00000138529
si:dkeyp-23e4.3
chr2_-_24348948 1.98 ENSDART00000136559
anoctamin 8a
chr4_-_992063 1.97 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
N-acetylgalactosaminidase, alpha
chr6_-_40713183 1.96 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
chr16_+_38119004 1.96 ENSDART00000132087
pogo transposable element derived with ZNF domain b
chr6_-_41085443 1.95 ENSDART00000143944
ENSDART00000028217
serine/arginine-rich splicing factor 3a
chr21_-_2172924 1.95 ENSDART00000169262
zgc:163077
chr1_+_40034061 1.95 ENSDART00000011727
coiled-coil domain containing 149b
chr24_-_24959607 1.95 ENSDART00000146930
ENSDART00000184482
pyruvate dehydrogenase kinase, isozyme 3a
chr2_+_47471647 1.94 ENSDART00000184199
acyl-CoA synthetase long chain family member 3b
chr21_-_7035599 1.94 ENSDART00000139777
si:ch211-93g21.1
chr13_+_28705143 1.94 ENSDART00000183338
LIM domain binding 1a
chr5_-_30079434 1.94 ENSDART00000133981
beta-carotene oxygenase 2a
chr18_+_36582815 1.93 ENSDART00000059311
sialic acid acetylesterase
chr20_+_23947004 1.93 ENSDART00000144195
caspase 8 associated protein 2
chr15_-_41734639 1.93 ENSDART00000154230
ENSDART00000167443
finTRIM family, member 90
chr8_-_52715911 1.93 ENSDART00000168241
tubulin, beta 2b
chr20_-_18382708 1.93 ENSDART00000170864
ENSDART00000166762
ENSDART00000191333
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr15_+_36445350 1.92 ENSDART00000154552
si:dkey-262k9.2
chr1_+_45740183 1.91 ENSDART00000149116
si:ch211-214c7.4
chr1_+_55293424 1.91 ENSDART00000152464
zgc:172106
chr3_-_21061931 1.91 ENSDART00000036741
family with sequence similarity 57, member Ba
chr17_-_24890843 1.91 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
UDP-galactose-4-epimerase
chr3_+_24681855 1.90 ENSDART00000170809
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein), member 17
chr14_+_20893065 1.90 ENSDART00000079452
lysozyme g-like 1
chr3_-_40945710 1.89 ENSDART00000138719
ENSDART00000102416
cytochrome P450, family 3, subfamily C, polypeptide 4
chr4_+_9612574 1.89 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
transmembrane protein 243, mitochondrial b
chr7_-_58178807 1.88 ENSDART00000188531
neutral sphingomyelinase (N-SMase) activation associated factor
chr10_+_36439293 1.88 ENSDART00000043802
ubiquitin specific peptidase like 1
chr10_+_36441124 1.87 ENSDART00000185626
ubiquitin specific peptidase like 1
chr22_-_6777976 1.86 ENSDART00000187946

chr17_-_42842129 1.86 ENSDART00000009528
molybdenum cofactor synthesis 3
chr7_+_7019911 1.86 ENSDART00000172421
RNA binding motif protein 14b
chr21_+_45496442 1.86 ENSDART00000164880
si:dkey-223p19.1
chr8_-_37249991 1.85 ENSDART00000189275
ENSDART00000178556
RNA binding motif protein 39b
chr8_+_31248917 1.85 ENSDART00000112170
un-named hu7912
chr5_+_4366431 1.83 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr15_-_28904371 1.82 ENSDART00000155154
echinoderm microtubule associated protein like 2
chr4_+_17671614 1.81 ENSDART00000121714
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr10_+_21789954 1.80 ENSDART00000157769
ENSDART00000171703
protocadherin 1 gamma c 5
chr16_+_46401756 1.79 ENSDART00000147370
ENSDART00000144000
rapunzel 2
chr1_+_36722122 1.79 ENSDART00000111566
transmembrane protein 184C
chr7_+_26716321 1.78 ENSDART00000189750
CD82 molecule a
chr2_-_56095275 1.78 ENSDART00000154701
si:ch211-178n15.1
chr2_-_42415902 1.77 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr23_+_31979602 1.76 ENSDART00000140351
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr14_-_30724165 1.75 ENSDART00000020936
fibroblast growth factor (acidic) intracellular binding protein a
chr13_+_11439486 1.74 ENSDART00000138312
zinc finger and BTB domain containing 18
chr5_-_35264517 1.74 ENSDART00000114981
pentatricopeptide repeat domain 2
chr24_-_982443 1.73 ENSDART00000063151
N-ethylmaleimide-sensitive factor attachment protein, gamma a

Network of associatons between targets according to the STRING database.

First level regulatory network of ehf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.2 8.3 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
1.1 3.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.1 6.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.9 3.7 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.8 3.3 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.8 4.9 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.8 1.5 GO:0006465 signal peptide processing(GO:0006465)
0.7 3.7 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.7 2.9 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.7 2.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.7 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.7 2.7 GO:0051645 Golgi localization(GO:0051645)
0.7 4.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.6 1.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 3.6 GO:0070254 mucus secretion(GO:0070254)
0.5 1.6 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.5 1.4 GO:0035046 pronuclear migration(GO:0035046)
0.5 1.4 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.5 1.4 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.5 2.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 1.8 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.5 1.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 1.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 2.0 GO:0002159 desmosome assembly(GO:0002159)
0.4 1.6 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 1.9 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.4 2.6 GO:0001839 neural plate morphogenesis(GO:0001839)
0.4 1.1 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.3 3.8 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.3 2.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.3 1.4 GO:0006740 NADPH regeneration(GO:0006740)
0.3 3.4 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.3 1.9 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 1.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.3 1.6 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 3.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.3 1.9 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.3 3.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.3 0.9 GO:0006089 lactate metabolic process(GO:0006089)
0.3 1.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.3 1.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 1.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.3 0.9 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 8.1 GO:0051923 sulfation(GO:0051923)
0.3 1.2 GO:0060074 synapse maturation(GO:0060074)
0.3 3.5 GO:0033198 response to ATP(GO:0033198)
0.3 0.8 GO:0071514 genetic imprinting(GO:0071514)
0.3 3.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 1.4 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.3 1.1 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 1.4 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.3 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 1.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.3 1.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 1.3 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.3 1.0 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.3 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.3 2.5 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 0.7 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 2.9 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 6.8 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.2 2.5 GO:0009791 post-embryonic development(GO:0009791)
0.2 2.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 1.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 1.2 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 2.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.2 0.6 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 1.2 GO:0032218 riboflavin transport(GO:0032218)
0.2 1.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.6 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 1.3 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 2.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 1.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 8.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.6 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 2.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 3.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 1.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 1.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.0 GO:0089718 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.2 1.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.2 1.6 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 2.8 GO:0097324 melanocyte migration(GO:0097324)
0.2 2.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 1.7 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 0.5 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 2.5 GO:0060021 palate development(GO:0060021)
0.1 1.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.9 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 1.3 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1 1.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.8 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 4.0 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 1.2 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 1.7 GO:0050684 regulation of mRNA processing(GO:0050684)
0.1 2.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 3.1 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 2.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 2.6 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 2.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 3.0 GO:0051125 regulation of actin nucleation(GO:0051125)
0.1 1.2 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.1 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0046324 regulation of glucose import(GO:0046324)
0.1 1.5 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 2.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.8 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.8 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 5.9 GO:0006414 translational elongation(GO:0006414)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 1.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 1.1 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.0 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 3.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.6 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 2.1 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.2 GO:0048899 anterior lateral line development(GO:0048899)
0.1 2.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.5 GO:0007032 endosome organization(GO:0007032)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 2.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 2.5 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.2 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.1 1.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0043584 nose development(GO:0043584)
0.1 2.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 5.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 5.1 GO:0048278 vesicle docking(GO:0048278)
0.1 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.7 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.2 GO:0043486 histone exchange(GO:0043486)
0.1 6.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.5 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 1.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.2 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.1 1.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.2 GO:0090148 membrane fission(GO:0090148)
0.0 0.5 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 1.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 3.3 GO:0006476 protein deacetylation(GO:0006476)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.1 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.3 GO:0031647 regulation of protein stability(GO:0031647)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.1 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.7 GO:1901655 cellular response to ketone(GO:1901655)
0.0 2.4 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 2.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 5.8 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 3.0 GO:0010469 regulation of receptor activity(GO:0010469)
0.0 0.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.8 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.6 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 2.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.4 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 1.3 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 1.1 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 8.5 GO:0072657 protein localization to membrane(GO:0072657)
0.0 1.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.3 GO:0034341 response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513) determination of ventral identity(GO:0048264)
0.0 0.2 GO:0034552 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 5.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.6 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.1 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.8 GO:0001878 response to yeast(GO:0001878)
0.0 0.8 GO:0048794 swim bladder development(GO:0048794)
0.0 1.5 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.4 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.8 GO:0002218 activation of innate immune response(GO:0002218) pattern recognition receptor signaling pathway(GO:0002221) innate immune response-activating signal transduction(GO:0002758)
0.0 2.6 GO:0008544 epidermis development(GO:0008544)
0.0 9.2 GO:0006886 intracellular protein transport(GO:0006886)
0.0 1.0 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.9 GO:0010970 establishment of localization by movement along microtubule(GO:0010970)
0.0 1.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 5.4 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 1.4 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.2 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 1.4 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.8 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.5 GO:0032868 response to insulin(GO:0032868) cellular response to insulin stimulus(GO:0032869)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 0.5 GO:2000146 negative regulation of cell migration(GO:0030336) negative regulation of cell motility(GO:2000146)
0.0 0.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 1.0 GO:0008380 RNA splicing(GO:0008380)
0.0 0.2 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0016358 dendrite development(GO:0016358)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0035339 SPOTS complex(GO:0035339)
0.8 3.1 GO:0043291 RAVE complex(GO:0043291)
0.6 3.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.6 1.8 GO:0031251 PAN complex(GO:0031251)
0.5 1.9 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.5 1.4 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.5 1.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 2.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 3.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.4 3.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 5.8 GO:0000815 ESCRT III complex(GO:0000815)
0.4 1.4 GO:0005787 signal peptidase complex(GO:0005787)
0.3 1.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 1.9 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.3 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 0.8 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 1.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.0 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 4.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 0.7 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 1.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 2.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 0.9 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 3.7 GO:0015030 Cajal body(GO:0015030)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.2 GO:0045095 keratin filament(GO:0045095)
0.2 2.0 GO:0000812 Swr1 complex(GO:0000812)
0.2 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 3.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 3.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.3 GO:0070449 elongin complex(GO:0070449)
0.1 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.9 GO:0030897 HOPS complex(GO:0030897)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0005771 multivesicular body(GO:0005771)
0.1 0.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 5.8 GO:0005811 lipid particle(GO:0005811)
0.1 6.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.3 GO:0032044 DSIF complex(GO:0032044)
0.1 8.7 GO:0031201 SNARE complex(GO:0031201)
0.1 2.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.0 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 3.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 20.0 GO:0005764 lysosome(GO:0005764)
0.1 0.6 GO:0034464 BBSome(GO:0034464)
0.1 1.7 GO:0005685 U1 snRNP(GO:0005685)
0.1 8.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.9 GO:0005770 late endosome(GO:0005770)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.0 GO:0030686 90S preribosome(GO:0030686)
0.1 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 6.8 GO:0016607 nuclear speck(GO:0016607)
0.1 2.4 GO:0030141 secretory granule(GO:0030141)
0.1 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.1 4.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0051233 spindle midzone(GO:0051233)
0.0 2.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 2.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 7.8 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 3.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 4.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0030990 intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.3 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 2.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 7.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.9 GO:0030027 lamellipodium(GO:0030027)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 12.8 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0032153 cell division site(GO:0032153)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.5 5.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.1 4.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
1.0 2.9 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.9 2.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.8 2.4 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.8 7.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.7 2.8 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.7 2.7 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.7 2.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.7 2.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 1.9 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.6 1.9 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.6 6.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 2.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 3.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.5 2.7 GO:0032183 SUMO binding(GO:0032183)
0.5 4.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 2.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 1.6 GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity(GO:0004777) succinate-semialdehyde dehydrogenase [NAD(P)+] activity(GO:0009013)
0.5 2.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 1.9 GO:0003796 lysozyme activity(GO:0003796)
0.5 1.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.5 2.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.5 1.4 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.4 4.0 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.4 3.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 4.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.4 1.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.6 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.3 3.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.4 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 1.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 1.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 1.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.3 3.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 0.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 1.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 3.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 4.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 1.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.3 1.9 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 4.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 1.8 GO:0019809 spermidine binding(GO:0019809)
0.3 1.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.2 3.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.2 GO:0008430 selenium binding(GO:0008430)
0.2 2.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 2.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 2.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 2.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 2.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 1.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.2 GO:0000995 transcription factor activity, core RNA polymerase binding(GO:0000990) transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 2.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 1.6 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 1.6 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.9 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 3.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 6.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 8.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 4.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 7.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.0 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 5.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 2.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 3.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 3.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 7.0 GO:0020037 heme binding(GO:0020037)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 14.6 GO:0003924 GTPase activity(GO:0003924)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.9 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.6 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.3 GO:0060090 binding, bridging(GO:0060090)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 2.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 2.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 3.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 3.4 PID IL5 PATHWAY IL5-mediated signaling events
0.2 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 2.8 PID EPO PATHWAY EPO signaling pathway
0.2 3.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 4.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 4.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 5.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 4.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 0.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.7 6.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.6 4.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 3.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 4.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 3.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 1.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 3.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.3 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 4.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 6.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes