ISMARA results: cux2b

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cux2b

Z-value: 1.31

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Transcription factors associated with cux2b

Gene Symbol	Gene ID	Gene Info
cux2b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000086345	cut-like homeobox 2b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
cux2b	dr11_v1_chr8_-_4097722_4097722	-0.35	4.9e-04	Click!

Activity profile of cux2b motif

Sorted Z-values of cux2b motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr25_+_31264155 Show fit	16.94	ENSDART00000012256	tnni2a.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I type 2a (skeletal, fast), tandem duplicate 3
chr3_-_61205711 Show fit	16.32	ENSDART00000055062	pvalb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	parvalbumin 1
chr25_+_29160102 Show fit	14.99	ENSDART00000162854	pkmb NCBI UniProt ZFIN ENSEMBL Google Show fit	pyruvate kinase M1/2b
chr5_-_71705191 Show fit	14.12	ENSDART00000187767	ak1 NCBI UniProt ZFIN ENSEMBL Google Show fit	adenylate kinase 1
chr11_-_18253111 Show fit	13.76	ENSDART00000125984	mustn1b NCBI UniProt ZFIN ENSEMBL Google Show fit	musculoskeletal, embryonic nuclear protein 1b
chr25_+_31267268 Show fit	13.09	ENSDART00000181239	tnni2a.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin I type 2a (skeletal, fast), tandem duplicate 3
chr11_+_11200550 Show fit	13.02	ENSDART00000181339 ENSDART00000187116	myom2a NCBI UniProt ZFIN ENSEMBL Google Show fit	myomesin 2a
chr24_+_38301080 Show fit	12.38	ENSDART00000105672	mybpc2b NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin binding protein C, fast type b
chr2_-_15324837 Show fit	11.97	ENSDART00000015655	tecrl2b NCBI UniProt ZFIN ENSEMBL Google Show fit	trans-2,3-enoyl-CoA reductase-like 2b
chr13_+_50375800 Show fit	11.93	ENSDART00000099537	cox5b2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome c oxidase subunit Vb 2
chr11_+_36243774 Show fit	11.70	ENSDART00000023323	zgc:172270 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:172270
chr5_+_51848756 Show fit	10.49	ENSDART00000087467 ENSDART00000184466	cmya5 NCBI UniProt ZFIN ENSEMBL Google Show fit	cardiomyopathy associated 5
chr19_+_43119698 Show fit	10.38	ENSDART00000167847 ENSDART00000186962 ENSDART00000187305	eef1a1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation elongation factor 1 alpha 1, like 1
chr23_+_32039386 Show fit	8.84	ENSDART00000133801	mylk2 NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin light chain kinase 2
chr6_+_3373665 Show fit	8.79	ENSDART00000134133	st3gal3a NCBI UniProt ZFIN ENSEMBL Google Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr19_-_48039400 Show fit	8.32	ENSDART00000166748 ENSDART00000165921	csf3b NCBI UniProt ZFIN ENSEMBL Google Show fit	colony stimulating factor 3 (granulocyte) b
chr3_-_21242460 Show fit	8.29	ENSDART00000007293	tcap NCBI UniProt ZFIN ENSEMBL Google Show fit	titin-cap (telethonin)
chr5_-_37886063 Show fit	7.90	ENSDART00000131378 ENSDART00000132152	si:ch211-139a5.9 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-139a5.9
chr2_-_30324610 Show fit	7.85	ENSDART00000185422	jph1b NCBI UniProt ZFIN ENSEMBL Google Show fit	junctophilin 1b
chr20_+_20499869 Show fit	7.72	ENSDART00000036124	six1b NCBI UniProt ZFIN ENSEMBL Google Show fit	SIX homeobox 1b
chr11_-_34065718 Show fit	7.58	ENSDART00000110608	col6a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type VI, alpha 1
chr23_-_21515182 Show fit	7.47	ENSDART00000142000	rnf207b NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 207b
chr5_-_38820046 Show fit	7.36	ENSDART00000182886	cnot6l NCBI UniProt ZFIN ENSEMBL Google Show fit	CCR4-NOT transcription complex, subunit 6-like
chr8_+_554531 Show fit	7.27	ENSDART00000193623	FO704758.2 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr8_+_27807266 Show fit	7.27	ENSDART00000170037	capza1b NCBI UniProt ZFIN ENSEMBL Google Show fit	capping protein (actin filament) muscle Z-line, alpha 1b
chr4_-_77135340 Show fit	7.16	ENSDART00000180581 ENSDART00000179901	CU467646.7 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr15_-_20933574 Show fit	7.14	ENSDART00000152648 ENSDART00000152448 ENSDART00000152244	usp2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin specific peptidase 2a
chr1_-_45049603 Show fit	7.13	ENSDART00000023336	rps6 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S6
chr4_-_10599062 Show fit	7.03	ENSDART00000048003	tspan12 NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 12
chr23_-_31506854 Show fit	6.88	ENSDART00000131352 ENSDART00000138625 ENSDART00000133002	eya4 NCBI UniProt ZFIN ENSEMBL Google Show fit	EYA transcriptional coactivator and phosphatase 4
chr2_+_51028269 Show fit	6.69	ENSDART00000161254	eef1da NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr22_+_396840 Show fit	6.66	ENSDART00000163198	capzb NCBI UniProt ZFIN ENSEMBL Google Show fit	capping protein (actin filament) muscle Z-line, beta
chr14_+_46020571 Show fit	6.53	ENSDART00000157617 ENSDART00000083928	c1qtnf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	C1q and TNF related 2
chr16_+_54780544 Show fit	6.42	ENSDART00000126646	si:zfos-1192g2.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-1192g2.3
chr12_+_20641471 Show fit	6.40	ENSDART00000133654	calcoco2 NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium binding and coiled-coil domain 2
chr24_-_21952164 Show fit	6.38	ENSDART00000058948	acot9.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	acyl-CoA thioesterase 9, tandem duplicate 2
chr14_-_970853 Show fit	6.37	ENSDART00000130801	acsl1b NCBI UniProt ZFIN ENSEMBL Google Show fit	acyl-CoA synthetase long chain family member 1b
chr10_-_7756865 Show fit	6.20	ENSDART00000114373 ENSDART00000125407 ENSDART00000016317	loxa NCBI UniProt ZFIN ENSEMBL Google Show fit	lysyl oxidase a
chr17_-_2578026 Show fit	6.19	ENSDART00000065821	zp3.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr16_-_33001153 Show fit	6.16	ENSDART00000147941	me1 NCBI UniProt ZFIN ENSEMBL Google Show fit	malic enzyme 1, NADP(+)-dependent, cytosolic
chr12_-_49151326 Show fit	6.01	ENSDART00000153244	bub3 NCBI UniProt ZFIN ENSEMBL Google Show fit	BUB3 mitotic checkpoint protein
chr8_+_44783424 Show fit	6.01	ENSDART00000025875	si:ch1073-459j12.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-459j12.1
chr17_-_2584423 Show fit	5.98	ENSDART00000013506	zp3.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr19_+_48102560 Show fit	5.85	ENSDART00000164464	utp18 NCBI UniProt ZFIN ENSEMBL Google Show fit	UTP18 small subunit (SSU) processome component
chr17_+_27434626 Show fit	5.75	ENSDART00000052446	vgll2b NCBI UniProt ZFIN ENSEMBL Google Show fit	vestigial-like family member 2b
chr14_-_899170 Show fit	5.63	ENSDART00000165211 ENSDART00000031992	rgs14a NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of G protein signaling 14a
chr13_-_22843562 Show fit	5.59	ENSDART00000142738	pbld NCBI UniProt ZFIN ENSEMBL Google Show fit	phenazine biosynthesis like protein domain containing
chr25_+_16194450 Show fit	5.49	ENSDART00000141994	mical2b NCBI UniProt ZFIN ENSEMBL Google Show fit	microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr12_-_26407092 Show fit	5.42	ENSDART00000178687	myoz1b NCBI UniProt ZFIN ENSEMBL Google Show fit	myozenin 1b
chr4_+_77933084 Show fit	5.36	ENSDART00000148728	pacsin2 NCBI UniProt ZFIN ENSEMBL Google Show fit	protein kinase C and casein kinase substrate in neurons 2
chr17_-_2573021 Show fit	5.32	ENSDART00000074181	zp3.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr3_-_48559906 Show fit	5.29	ENSDART00000160370	atp5pd NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP synthase peripheral stalk subunit d
chr19_+_5674907 Show fit	5.16	ENSDART00000042189	pdk2b NCBI UniProt ZFIN ENSEMBL Google Show fit	pyruvate dehydrogenase kinase, isozyme 2b
chr18_+_33468099 Show fit	5.11	ENSDART00000131769	v2rh9 NCBI UniProt ZFIN ENSEMBL Google Show fit	vomeronasal 2 receptor, h9
chr12_-_48970299 Show fit	5.01	ENSDART00000163734	rgrb NCBI UniProt ZFIN ENSEMBL Google Show fit	retinal G protein coupled receptor b
chr4_-_21652812 Show fit	4.96	ENSDART00000174400	rps16 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S16
chr25_+_37435720 Show fit	4.95	ENSDART00000164390	chmp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	charged multivesicular body protein 1A
chr13_+_35635672 Show fit	4.92	ENSDART00000148481	thbs2a NCBI UniProt ZFIN ENSEMBL Google Show fit	thrombospondin 2a
chr17_-_8899323 Show fit	4.88	ENSDART00000081590	nkl.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NK-lysin tandem duplicate 1
chr11_-_29658396 Show fit	4.80	ENSDART00000183947	rpl22 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L22
chr4_-_77135076 Show fit	4.78	ENSDART00000174184	zgc:173770 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:173770
chr19_-_38539670 Show fit	4.76	ENSDART00000136775	col16a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type XVI, alpha 1
chr4_-_12914163 Show fit	4.69	ENSDART00000140002 ENSDART00000145917 ENSDART00000141355 ENSDART00000067135	msrb3 NCBI UniProt ZFIN ENSEMBL Google Show fit	methionine sulfoxide reductase B3
chr23_-_9925568 Show fit	4.68	ENSDART00000081268	si:ch211-220i18.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-220i18.4
chr23_+_32101202 Show fit	4.63	ENSDART00000000992	zgc:56699 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:56699
chr22_-_15602760 Show fit	4.62	ENSDART00000009054	tpm4a NCBI UniProt ZFIN ENSEMBL Google Show fit	tropomyosin 4a
chr9_-_49493305 Show fit	4.62	ENSDART00000148707 ENSDART00000148561	xirp2b NCBI UniProt ZFIN ENSEMBL Google Show fit	xin actin binding repeat containing 2b
chr1_+_27690 Show fit	4.61	ENSDART00000162928	eed NCBI UniProt ZFIN ENSEMBL Google Show fit	embryonic ectoderm development
chr16_+_29509133 Show fit	4.59	ENSDART00000112116	ctss2.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin S, ortholog2, tandem duplicate 1
chr17_-_2590222 Show fit	4.52	ENSDART00000185711	CR759892.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr6_-_46742455 Show fit	4.50	ENSDART00000011970	zgc:66479 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:66479
chr18_+_16986495 Show fit	4.50	ENSDART00000147377	si:ch211-218c6.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-218c6.8
chr4_-_77125693 Show fit	4.49	ENSDART00000174256	CU467646.3 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr22_+_19290199 Show fit	4.49	ENSDART00000148173	si:dkey-21e2.15 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-21e2.15
chr18_-_20869175 Show fit	4.42	ENSDART00000090079	synm NCBI UniProt ZFIN ENSEMBL Google Show fit	synemin, intermediate filament protein
chr19_-_48391415 Show fit	4.35	ENSDART00000170726 ENSDART00000169577	si:ch73-359m17.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-359m17.2
chr2_-_42958619 Show fit	4.32	ENSDART00000144317	oc90 NCBI UniProt ZFIN ENSEMBL Google Show fit	otoconin 90
chr16_+_35870456 Show fit	4.22	ENSDART00000184321	thrap3a NCBI UniProt ZFIN ENSEMBL Google Show fit	thyroid hormone receptor associated protein 3a
chr14_-_52480661 Show fit	4.19	ENSDART00000158353	exosc3 NCBI UniProt ZFIN ENSEMBL Google Show fit	exosome component 3
chr12_+_47663419 Show fit	4.17	ENSDART00000171932	HHEX NCBI UniProt ZFIN ENSEMBL Google Show fit	hematopoietically expressed homeobox
chr19_+_627899 Show fit	4.13	ENSDART00000148508	tert NCBI UniProt ZFIN ENSEMBL Google Show fit	telomerase reverse transcriptase
chr14_+_46020282 Show fit	4.11	ENSDART00000190087	c1qtnf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	C1q and TNF related 2
chr2_+_20605186 Show fit	4.08	ENSDART00000128505	olfml2bb NCBI UniProt ZFIN ENSEMBL Google Show fit	olfactomedin-like 2Bb
chr6_+_2097690 Show fit	4.07	ENSDART00000193770	tgm2b NCBI UniProt ZFIN ENSEMBL Google Show fit	transglutaminase 2b
chr4_+_25223050 Show fit	4.05	ENSDART00000138121	itih5 NCBI UniProt ZFIN ENSEMBL Google Show fit	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_44500201 Show fit	4.05	ENSDART00000150460	si:dkeyp-100h4.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-100h4.7
chr11_-_29657947 Show fit	4.02	ENSDART00000125753	rpl22 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L22
chr9_+_9112943 Show fit	4.00	ENSDART00000083033	sik1 NCBI UniProt ZFIN ENSEMBL Google Show fit	salt-inducible kinase 1
chr3_-_8272632 Show fit	4.00	ENSDART00000143522	cyp2k6 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 2, subfamily K, polypeptide 6
chr4_-_77130289 Show fit	3.99	ENSDART00000174380	CU467646.7 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr7_+_61480296 Show fit	3.97	ENSDART00000083255	adam19a NCBI UniProt ZFIN ENSEMBL Google Show fit	ADAM metallopeptidase domain 19a
chr7_+_30933867 Show fit	3.93	ENSDART00000156325	tjp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	tight junction protein 1a
chr16_+_13965923 Show fit	3.86	ENSDART00000103857	zgc:162509 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:162509
chr14_+_30568961 Show fit	3.84	ENSDART00000184303	mrpl11 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial ribosomal protein L11
chr20_-_40754794 Show fit	3.83	ENSDART00000187251	cx32.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	connexin 32.3
chr2_+_45511459 Show fit	3.83	ENSDART00000132101	aknad1 NCBI UniProt ZFIN ENSEMBL Google Show fit	AKNA domain containing 1
chr25_+_37290206 Show fit	3.83	ENSDART00000086474	si:dkey-234i14.12 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-234i14.12
chr13_-_290377 Show fit	3.79	ENSDART00000134963	chs1 NCBI UniProt ZFIN ENSEMBL Google Show fit	chitin synthase 1
chr10_-_21545091 Show fit	3.76	ENSDART00000029122 ENSDART00000132207	zgc:165539 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:165539
chr9_+_13120419 Show fit	3.75	ENSDART00000141005	fam117bb NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 117, member Bb
chr13_+_46941930 Show fit	3.71	ENSDART00000056962	fbxo5 NCBI UniProt ZFIN ENSEMBL Google Show fit	F-box protein 5
chr10_-_24391716 Show fit	3.69	ENSDART00000141332 ENSDART00000100772	slc43a2b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 43 (amino acid system L transporter), member 2b
chr7_+_30626378 Show fit	3.68	ENSDART00000173533 ENSDART00000052541	ccnb2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin B2
chr4_-_77140030 Show fit	3.67	ENSDART00000174332 ENSDART00000190394 ENSDART00000189208	CU467646.5 NCBI UniProt ZFIN ENSEMBL Google Show fit CU467646.7 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr9_-_49964810 Show fit	3.67	ENSDART00000167098	scn1a NCBI UniProt ZFIN ENSEMBL Google Show fit	sodium channel, voltage-gated, type I, alpha
chr14_-_34512859 Show fit	3.61	ENSDART00000140368	si:ch211-232m8.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-232m8.3
chr7_-_4461104 Show fit	3.59	ENSDART00000023090 ENSDART00000140770	slc12a10.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr2_+_24936766 Show fit	3.58	ENSDART00000025962	gyg1a NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogenin 1a
chr1_+_57041549 Show fit	3.54	ENSDART00000152198	si:ch211-1f22.16 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-1f22.16
chr11_-_37589293 Show fit	3.54	ENSDART00000172989	bsnb NCBI UniProt ZFIN ENSEMBL Google Show fit	bassoon (presynaptic cytomatrix protein) b
chr24_-_31306724 Show fit	3.53	ENSDART00000165399	acp5b NCBI UniProt ZFIN ENSEMBL Google Show fit	acid phosphatase 5b, tartrate resistant
chr5_+_6672870 Show fit	3.51	ENSDART00000126598	pxna NCBI UniProt ZFIN ENSEMBL Google Show fit	paxillin a
chr2_+_20605925 Show fit	3.49	ENSDART00000191510	olfml2bb NCBI UniProt ZFIN ENSEMBL Google Show fit	olfactomedin-like 2Bb
chr10_-_40964739 Show fit	3.46	ENSDART00000076359	npffr1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	neuropeptide FF receptor 1 like 1
chr1_-_38815361 Show fit	3.44	ENSDART00000148790 ENSDART00000148572 ENSDART00000149080	asb5b NCBI UniProt ZFIN ENSEMBL Google Show fit	ankyrin repeat and SOCS box containing 5b
chr13_-_9442942 Show fit	3.43	ENSDART00000138833	grxcr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	glutaredoxin, cysteine rich 1
chr12_+_16284086 Show fit	3.40	ENSDART00000013360 ENSDART00000141169	ppp1r3cb NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 1, regulatory subunit 3Cb
chr25_+_22320738 Show fit	3.38	ENSDART00000073566	cyp11a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 11, subfamily A, polypeptide 1
chr25_-_37319117 Show fit	3.36	ENSDART00000044499	igl4v9 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin light 4 variable 9
chr19_-_40199081 Show fit	3.36	ENSDART00000051970 ENSDART00000151079	grn2 NCBI UniProt ZFIN ENSEMBL Google Show fit	granulin 2
chr21_-_19314618 Show fit	3.36	ENSDART00000188744	gpat3 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycerol-3-phosphate acyltransferase 3
chr23_-_33750135 Show fit	3.33	ENSDART00000187641	bin2a NCBI UniProt ZFIN ENSEMBL Google Show fit	bridging integrator 2a
chr9_-_23990416 Show fit	3.28	ENSDART00000113176	col6a3 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type VI, alpha 3
chr21_+_17768174 Show fit	3.28	ENSDART00000141380	rxraa NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoid X receptor, alpha a
chr2_-_45510699 Show fit	3.26	ENSDART00000024034 ENSDART00000145634	gpsm2 NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein signaling modulator 2
chr13_-_27354003 Show fit	3.21	ENSDART00000101479 ENSDART00000044652	ddx43 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr25_+_37297659 Show fit	3.20	ENSDART00000086733	si:dkey-234i14.13 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-234i14.13
chr24_+_25913162 Show fit	3.17	ENSDART00000143099 ENSDART00000184814	map3k15 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitogen-activated protein kinase kinase kinase 15
chr7_+_4824882 Show fit	3.17	ENSDART00000137369	si:dkey-28d5.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-28d5.7
chr8_-_4327473 Show fit	3.17	ENSDART00000134378	cux2b NCBI UniProt ZFIN ENSEMBL Google Show fit	cut-like homeobox 2b
chr7_-_38658411 Show fit	3.16	ENSDART00000109463 ENSDART00000017155	npsn NCBI UniProt ZFIN ENSEMBL Google Show fit	nephrosin
chr11_-_27962757 Show fit	3.13	ENSDART00000147386	ece1 NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin converting enzyme 1
chr6_+_52235441 Show fit	3.13	ENSDART00000056319	cox6c NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome c oxidase subunit VIc
chr4_+_44454270 Show fit	3.12	ENSDART00000150482	si:dkeyp-100h4.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-100h4.4
chr18_-_1414760 Show fit	3.12	ENSDART00000171881	PEPD NCBI UniProt ZFIN ENSEMBL Google Show fit	peptidase D
chr16_-_13965518 Show fit	3.08	ENSDART00000138304	si:dkey-85k15.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-85k15.4
chr3_-_5277041 Show fit	3.04	ENSDART00000046995	txn2 NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin 2
chr24_-_39826865 Show fit	3.03	ENSDART00000089232	slc12a7b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 12 (potassium/chloride transporter), member 7b
chr20_-_23842631 Show fit	3.02	ENSDART00000153079	si:dkey-15j16.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-15j16.3
chr6_-_33875919 Show fit	2.99	ENSDART00000190411	tmem69 NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 69
chr11_+_10984293 Show fit	2.98	ENSDART00000065933	itgb6 NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, beta 6
chr25_+_36349574 Show fit	2.98	ENSDART00000184101	zgc:173552 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:173552
chr17_-_15747296 Show fit	2.96	ENSDART00000153970	cx52.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	connexin 52.7
chr1_-_34713710 Show fit	2.93	ENSDART00000141569 ENSDART00000102111 ENSDART00000122137	tpt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	tumor protein, translationally-controlled 1
chr17_-_681142 Show fit	2.93	ENSDART00000165583	soul3 NCBI UniProt ZFIN ENSEMBL Google Show fit	heme-binding protein soul3
chr7_-_6441865 Show fit	2.92	ENSDART00000172831	hist1h2a10 NCBI UniProt ZFIN ENSEMBL Google Show fit	histone cluster 1 H2A family member 10
chr8_-_3773374 Show fit	2.92	ENSDART00000115036	bicdl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	BICD family like cargo adaptor 1
chr20_+_38910214 Show fit	2.91	ENSDART00000047362	msra NCBI UniProt ZFIN ENSEMBL Google Show fit	methionine sulfoxide reductase A
chr17_-_34952562 Show fit	2.90	ENSDART00000021128	kidins220a NCBI UniProt ZFIN ENSEMBL Google Show fit	kinase D-interacting substrate 220a
chr11_+_37201483 Show fit	2.90	ENSDART00000160930 ENSDART00000173439 ENSDART00000171273	zgc:112265 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:112265
chr9_-_5318873 Show fit	2.88	ENSDART00000129308	ACVR1C NCBI UniProt ZFIN ENSEMBL Google Show fit	activin A receptor type 1C
chr25_-_19661198 Show fit	2.88	ENSDART00000149641	atp2b1b NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase plasma membrane Ca2+ transporting 1b
chr21_-_5881344 Show fit	2.86	ENSDART00000009241	rpl35 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L35
chr2_+_36004381 Show fit	2.86	ENSDART00000098706	lamc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	laminin, gamma 2
chr8_-_45760087 Show fit	2.86	ENSDART00000025620	ppiaa NCBI UniProt ZFIN ENSEMBL Google Show fit	peptidylprolyl isomerase Aa (cyclophilin A)
chr19_+_34274504 Show fit	2.84	ENSDART00000132046	si:ch211-9n13.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-9n13.3
chr2_+_21634128 Show fit	2.82	ENSDART00000089822	fbxl7 NCBI UniProt ZFIN ENSEMBL Google Show fit	F-box and leucine-rich repeat protein 7
chr20_+_20726231 Show fit	2.82	ENSDART00000147112	zgc:193541 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:193541
chr21_+_5531138 Show fit	2.82	ENSDART00000163825	ly6m6 NCBI UniProt ZFIN ENSEMBL Google Show fit	lymphocyte antigen 6 family member M6
chr3_-_8246309 Show fit	2.81	ENSDART00000134497 ENSDART00000015232	cyp2k22 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 2, subfamily K, polypeptide 22
chr23_-_43424510 Show fit	2.80	ENSDART00000055564	rprd1b NCBI UniProt ZFIN ENSEMBL Google Show fit	regulation of nuclear pre-mRNA domain containing 1B
chr13_+_51869025 Show fit	2.80	ENSDART00000187066	LT631684.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr23_-_5818992 Show fit	2.79	ENSDART00000148730	csrp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	cysteine and glycine-rich protein 1a
chr4_-_17680493 Show fit	2.77	ENSDART00000180131	BX890572.2 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr17_+_35362851 Show fit	2.76	ENSDART00000137659	cmpk2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_+_21990095 Show fit	2.76	ENSDART00000146829 ENSDART00000133515 ENSDART00000193582	si:dkey-57a22.13 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-57a22.13
chr4_+_25574827 Show fit	2.75	ENSDART00000187726	zgc:195175 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:195175
chr7_-_73854476 Show fit	2.75	ENSDART00000186481	zgc:173552 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:173552
chr9_+_55455801 Show fit	2.74	ENSDART00000144757 ENSDART00000186543	mxra5b NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix-remodelling associated 5b
chr1_-_52498146 Show fit	2.72	ENSDART00000122217	acy3.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr18_-_6766354 Show fit	2.71	ENSDART00000132611	adm2b NCBI UniProt ZFIN ENSEMBL Google Show fit	adrenomedullin 2b
chr13_+_37273010 Show fit	2.69	ENSDART00000144387	gphb5 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycoprotein hormone beta 5
chr12_+_9342502 Show fit	2.66	ENSDART00000152808	kcnh6b NCBI UniProt ZFIN ENSEMBL Google Show fit	potassium voltage-gated channel, subfamily H (eag-related), member 6b
chr7_-_29292206 Show fit	2.66	ENSDART00000086753	dapk2a NCBI UniProt ZFIN ENSEMBL Google Show fit	death-associated protein kinase 2a
chr13_+_37273221 Show fit	2.65	ENSDART00000035011	gphb5 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycoprotein hormone beta 5
chr2_+_56657804 Show fit	2.64	ENSDART00000113964	POLR2E (1 of many) NCBI UniProt ZFIN ENSEMBL Google Show fit	RNA polymerase II subunit E
chr2_-_19520324 Show fit	2.62	ENSDART00000079877	pimr52 NCBI UniProt ZFIN ENSEMBL Google Show fit	Pim proto-oncogene, serine/threonine kinase, related 52
chr23_-_45705525 Show fit	2.62	ENSDART00000148959	ednrab NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin receptor type Ab
chr2_-_6262441 Show fit	2.60	ENSDART00000092190	arl14 NCBI UniProt ZFIN ENSEMBL Google Show fit	ADP-ribosylation factor-like 14
chr8_+_3496204 Show fit	2.58	ENSDART00000085993	pxnb NCBI UniProt ZFIN ENSEMBL Google Show fit	paxillin b
chr11_+_21096339 Show fit	2.58	ENSDART00000124574	il19l NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 19 like
chr2_-_51794472 Show fit	2.58	ENSDART00000186652	BX908782.3 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr4_-_9852318 Show fit	2.58	ENSDART00000080702	glt8d2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycosyltransferase 8 domain containing 2
chr2_-_7845110 Show fit	2.57	ENSDART00000091987	si:ch211-38m6.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-38m6.7
chr8_+_27807974 Show fit	2.56	ENSDART00000078509	capza1b NCBI UniProt ZFIN ENSEMBL Google Show fit	capping protein (actin filament) muscle Z-line, alpha 1b
chr1_+_524717 Show fit	2.56	ENSDART00000102421 ENSDART00000184473	mrpl16 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial ribosomal protein L16
chr1_+_292545 Show fit	2.53	ENSDART00000148261	cenpe NCBI UniProt ZFIN ENSEMBL Google Show fit	centromere protein E
chr24_-_27452488 Show fit	2.52	ENSDART00000136433	ccl34b.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 34b, duplicate 8
chr7_-_35432901 Show fit	2.52	ENSDART00000026712	mmp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix metallopeptidase 2
chr5_+_56026031 Show fit	2.51	ENSDART00000050970	fzd9a NCBI UniProt ZFIN ENSEMBL Google Show fit	frizzled class receptor 9a
chr3_-_34096987 Show fit	2.51	ENSDART00000151663	ighv4-5 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin heavy variable 4-5
chr12_+_47698356 Show fit	2.51	ENSDART00000112010	lzts2b NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine zipper, putative tumor suppressor 2b
chr25_-_37322081 Show fit	2.50	ENSDART00000128285	igl4v10 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin light 4 variable 10
chr8_-_53044300 Show fit	2.49	ENSDART00000191653	nr6a1a NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear receptor subfamily 6, group A, member 1a
chr12_+_16168342 Show fit	2.49	ENSDART00000079326 ENSDART00000170024	lrp2b NCBI UniProt ZFIN ENSEMBL Google Show fit	low density lipoprotein receptor-related protein 2b
chr17_+_53435279 Show fit	2.47	ENSDART00000126630	cx52.9 NCBI UniProt ZFIN ENSEMBL Google Show fit	connexin 52.9
chr17_+_6276559 Show fit	2.47	ENSDART00000131075	dusp23b NCBI UniProt ZFIN ENSEMBL Google Show fit	dual specificity phosphatase 23b
chr13_+_12671513 Show fit	2.47	ENSDART00000010517	eif4eb NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 4eb
chr7_+_16991711 Show fit	2.47	ENSDART00000173660	nav2a NCBI UniProt ZFIN ENSEMBL Google Show fit	neuron navigator 2a
chr10_-_41352502 Show fit	2.46	ENSDART00000052971 ENSDART00000128156	rab11fip1b NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB11 family interacting protein 1 (class I) b

Network of associatons between targets according to the STRING database.

First level regulatory network of cux2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	13.8	GO:0035988	chondrocyte proliferation(GO:0035988)
2.6	7.7	GO:0002074	extraocular skeletal muscle development(GO:0002074)
2.5	7.5	GO:1903779	regulation of cardiac conduction(GO:1903779)
2.1	6.4	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
2.1	8.3	GO:0035994	response to muscle stretch(GO:0035994)
2.0	14.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
2.0	5.9	GO:1901376	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
1.8	5.3	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
1.7	6.9	GO:0033301	cell cycle comprising mitosis without cytokinesis(GO:0033301)
1.7	17.1	GO:0070836	membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
1.4	4.2	GO:0071034	cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
1.4	4.1	GO:0007571	age-dependent general metabolic decline(GO:0007571)
1.3	6.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
1.3	3.9	GO:0060631	regulation of meiosis I(GO:0060631)
1.2	4.7	GO:0030091	protein repair(GO:0030091)
1.0	17.5	GO:0007339	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
1.0	5.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.9	5.7	GO:0071800	podosome assembly(GO:0071800)
0.9	3.7	GO:0051444	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.9	2.8	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.9	11.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9	5.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.8	6.9	GO:0016576	histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.8	3.8	GO:1901073	chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.7	4.5	GO:0032648	interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.7	2.9	GO:0055107	Golgi to secretory granule transport(GO:0055107)
0.7	7.2	GO:0006108	malate metabolic process(GO:0006108)
0.7	2.1	GO:0099623	regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.7	2.1	GO:0043455	regulation of secondary metabolic process(GO:0043455)
0.7	7.5	GO:1902547	regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.7	3.3	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.7	2.0	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.6	3.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.6	2.4	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.6	30.0	GO:0003009	skeletal muscle contraction(GO:0003009)
0.6	1.8	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.6	2.4	GO:0070257	regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.6	2.8	GO:0051414	response to cortisol(GO:0051414)
0.5	2.1	GO:0033153	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.5	1.6	GO:0006565	L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.5	2.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.5	1.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.5	16.8	GO:0002377	immunoglobulin production(GO:0002377)
0.5	2.4	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.5	8.3	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.4	1.3	GO:0060063	Spemann organizer formation at the embryonic shield(GO:0060063)
0.4	8.0	GO:0033077	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.4	1.8	GO:0021730	trigeminal sensory nucleus development(GO:0021730)
0.4	1.8	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.4	2.2	GO:0070986	left/right axis specification(GO:0070986)
0.4	2.2	GO:0017003	protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.4	1.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.4	2.6	GO:0005513	detection of calcium ion(GO:0005513)
0.4	20.0	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.4	3.4	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.4	6.1	GO:0061055	myotome development(GO:0061055)
0.4	1.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4	2.6	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4	2.6	GO:0003319	cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.4	1.9	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.4	6.2	GO:0018057	peptidyl-lysine oxidation(GO:0018057)
0.4	3.9	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4	3.5	GO:1904071	presynaptic active zone assembly(GO:1904071)
0.3	1.7	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.3	1.7	GO:0097066	response to thyroid hormone(GO:0097066)
0.3	2.4	GO:1990511	piRNA biosynthetic process(GO:1990511)
0.3	1.3	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.3	5.6	GO:0008354	germ cell migration(GO:0008354)
0.3	4.3	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.3	0.9	GO:0048785	hatching gland development(GO:0048785)
0.3	2.5	GO:0051013	microtubule severing(GO:0051013)
0.3	4.3	GO:1903963	icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3	7.7	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3	0.9	GO:0055109	invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3	6.8	GO:0071174	mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.3	2.3	GO:0051673	membrane disruption in other organism(GO:0051673)
0.3	0.8	GO:0002456	T cell cytokine production(GO:0002369) T cell mediated immunity(GO:0002456)
0.3	3.0	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.3	0.8	GO:0007414	axonal defasciculation(GO:0007414)
0.3	1.9	GO:2000377	regulation of reactive oxygen species metabolic process(GO:2000377)
0.3	1.8	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.3	2.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.3	17.1	GO:0006414	translational elongation(GO:0006414)
0.3	1.6	GO:0090342	regulation of cell aging(GO:0090342)
0.3	3.6	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.3	1.5	GO:1901016	regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.3	15.8	GO:0006096	glycolytic process(GO:0006096)
0.2	3.7	GO:0000186	activation of MAPKK activity(GO:0000186)
0.2	6.6	GO:0006884	cell volume homeostasis(GO:0006884)
0.2	0.7	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.2	1.2	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2	1.2	GO:0035678	neuromast hair cell morphogenesis(GO:0035678)
0.2	9.0	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.2	2.2	GO:0022615	protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2	1.1	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.2	4.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.2	3.1	GO:0016486	peptide hormone processing(GO:0016486)
0.2	9.1	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2	2.2	GO:1901317	regulation of sperm motility(GO:1901317)
0.2	0.8	GO:1903723	negative regulation of centriole elongation(GO:1903723)
0.2	0.9	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.2	0.6	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.2	4.1	GO:0018149	peptide cross-linking(GO:0018149)
0.2	1.3	GO:0031048	chromatin silencing by small RNA(GO:0031048)
0.2	1.3	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.2	2.6	GO:0034724	DNA replication-independent nucleosome organization(GO:0034724)
0.2	3.9	GO:0010675	regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.2	0.5	GO:0080120	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2	0.5	GO:0042730	fibrinolysis(GO:0042730)
0.2	5.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2	2.9	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2	0.5	GO:0036314	response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2	6.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.2	1.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	1.8	GO:1904103	regulation of convergent extension involved in gastrulation(GO:1904103)
0.2	5.0	GO:0032543	mitochondrial translation(GO:0032543)
0.2	4.3	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.2	1.7	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2	1.8	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1	1.0	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1	3.0	GO:0015671	oxygen transport(GO:0015671)
0.1	1.2	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	0.7	GO:0045056	transcytosis(GO:0045056)
0.1	7.7	GO:0006342	chromatin silencing(GO:0006342)
0.1	1.0	GO:0044211	CTP salvage(GO:0044211)
0.1	4.1	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.5	GO:2000660	regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	6.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.8	GO:0031960	response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.1	0.5	GO:0055130	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1	4.9	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.1	1.5	GO:0099638	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1	1.3	GO:0034394	protein localization to cell surface(GO:0034394)
0.1	2.6	GO:0006278	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1	0.9	GO:1902222	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	1.6	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	3.3	GO:0032526	response to retinoic acid(GO:0032526)
0.1	0.9	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1	0.6	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1	0.7	GO:0006012	galactose metabolic process(GO:0006012)
0.1	0.7	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.1	1.7	GO:0010669	epithelial structure maintenance(GO:0010669)
0.1	2.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.7	GO:0021588	cerebellum formation(GO:0021588)
0.1	1.1	GO:2000403	positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1	0.5	GO:0010269	response to selenium ion(GO:0010269)
0.1	0.4	GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1	0.8	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1	0.8	GO:0021778	oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	4.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.7	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1	1.2	GO:0043114	regulation of vascular permeability(GO:0043114)
0.1	0.8	GO:0031268	pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.8	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1	0.6	GO:0071357	response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1	1.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	2.8	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.1	2.4	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1	3.2	GO:0034599	cellular response to oxidative stress(GO:0034599)
0.1	0.6	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.1	2.7	GO:0015804	neutral amino acid transport(GO:0015804)
0.1	0.3	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1	1.2	GO:0030259	lipid glycosylation(GO:0030259)
0.1	1.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	1.7	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	7.7	GO:0006936	muscle contraction(GO:0006936)
0.1	1.6	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.1	4.2	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.3	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	1.3	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	2.9	GO:0043113	receptor clustering(GO:0043113)
0.1	1.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.6	GO:1901998	toxin transport(GO:1901998)
0.1	5.1	GO:0042742	defense response to bacterium(GO:0042742)
0.1	1.8	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1	3.1	GO:0006119	oxidative phosphorylation(GO:0006119)
0.1	0.5	GO:0042554	superoxide anion generation(GO:0042554)
0.1	1.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	18.1	GO:0060537	muscle tissue development(GO:0060537)
0.1	7.3	GO:0007283	spermatogenesis(GO:0007283)
0.1	1.7	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	1.2	GO:2001236	regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1	7.2	GO:0016579	protein deubiquitination(GO:0016579)
0.1	5.8	GO:0002088	lens development in camera-type eye(GO:0002088)
0.1	0.9	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	2.7	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1	1.6	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.1	1.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	1.1	GO:0009408	response to heat(GO:0009408)
0.1	4.3	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	1.9	GO:0030239	myofibril assembly(GO:0030239)
0.1	2.3	GO:0043627	response to estrogen(GO:0043627) cellular response to estrogen stimulus(GO:0071391)
0.0	0.6	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	1.2	GO:0030217	T cell differentiation(GO:0030217)
0.0	1.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	1.9	GO:0009566	single fertilization(GO:0007338) fertilization(GO:0009566)
0.0	1.6	GO:0016525	negative regulation of angiogenesis(GO:0016525)
0.0	0.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	1.4	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
0.0	0.5	GO:0006030	aminoglycan catabolic process(GO:0006026) chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) glucosamine-containing compound metabolic process(GO:1901071) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.5	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.5	GO:0019372	lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	1.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	2.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	1.2	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.3	GO:0097107	postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063) negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	3.4	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.0	0.4	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.9	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.3	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0	1.0	GO:0051923	sulfation(GO:0051923)
0.0	1.3	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.9	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	1.5	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	1.4	GO:0051262	protein tetramerization(GO:0051262)
0.0	1.0	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0060911	cardiac cell fate commitment(GO:0060911) cardiac cell fate specification(GO:0060912)
0.0	1.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.5	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.2	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.0	0.2	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	3.5	GO:0001503	ossification(GO:0001503)
0.0	12.6	GO:0007346	regulation of mitotic cell cycle(GO:0007346)
0.0	1.3	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	1.9	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	1.5	GO:0007602	phototransduction(GO:0007602)
0.0	6.4	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	1.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	1.1	GO:0030050	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0	0.5	GO:0035329	hippo signaling(GO:0035329)
0.0	0.4	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0	2.7	GO:0008284	positive regulation of cell proliferation(GO:0008284)
0.0	0.3	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.3	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	1.4	GO:0009190	cyclic nucleotide biosynthetic process(GO:0009190)
0.0	6.4	GO:0006412	translation(GO:0006412)
0.0	0.7	GO:0001946	lymphangiogenesis(GO:0001946)
0.0	1.5	GO:0009617	response to bacterium(GO:0009617)
0.0	0.8	GO:0070830	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0	1.3	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	2.5	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.0	5.2	GO:0006955	immune response(GO:0006955)
0.0	0.4	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.7	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.2	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.4	GO:0042552	myelination(GO:0042552)
0.0	0.9	GO:0021782	glial cell development(GO:0021782)
0.0	1.0	GO:0050768	negative regulation of neurogenesis(GO:0050768)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	16.5	GO:0008290	F-actin capping protein complex(GO:0008290)
1.6	7.8	GO:0030314	junctional membrane complex(GO:0030314)
1.4	4.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
1.0	7.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.0	3.0	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
1.0	6.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.8	5.7	GO:0001891	phagocytic cup(GO:0001891)
0.8	2.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.7	30.0	GO:0005861	troponin complex(GO:0005861)
0.6	13.0	GO:0031430	M band(GO:0031430)
0.6	8.5	GO:0000815	ESCRT III complex(GO:0000815)
0.6	2.3	GO:0070209	ASTRA complex(GO:0070209)
0.5	7.7	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5	3.8	GO:0030428	cell septum(GO:0030428)
0.4	1.7	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.4	2.0	GO:0034657	GID complex(GO:0034657)
0.4	17.1	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.4	4.2	GO:0000177	nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.4	3.5	GO:0098982	GABA-ergic synapse(GO:0098982)
0.3	4.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	4.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	1.5	GO:1990513	CLOCK-BMAL transcription complex(GO:1990513)
0.3	4.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.3	2.0	GO:0030914	STAGA complex(GO:0030914)
0.3	1.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.3	1.3	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.3	6.0	GO:0030014	CCR4-NOT complex(GO:0030014)
0.3	0.8	GO:0033186	CAF-1 complex(GO:0033186)
0.2	3.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	2.3	GO:0035101	FACT complex(GO:0035101)
0.2	8.8	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	18.7	GO:0030018	Z disc(GO:0030018)
0.2	1.9	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	3.3	GO:0097546	ciliary base(GO:0097546)
0.2	1.7	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	1.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	26.1	GO:0005840	ribosome(GO:0005840)
0.1	2.7	GO:0009925	basal plasma membrane(GO:0009925)
0.1	6.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	4.9	GO:0005581	collagen trimer(GO:0005581)
0.1	0.7	GO:0030870	Mre11 complex(GO:0030870)
0.1	1.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	4.9	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	1.1	GO:0098833	presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1	0.9	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	3.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	1.8	GO:0000780	condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	8.8	GO:0000786	nucleosome(GO:0000786)
0.1	1.0	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	3.6	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	3.2	GO:0005902	microvillus(GO:0005902)
0.1	28.6	GO:0031012	extracellular matrix(GO:0031012)
0.1	7.9	GO:0005924	cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1	1.7	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	6.2	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	7.4	GO:0016324	apical plasma membrane(GO:0016324)
0.1	5.8	GO:0005884	actin filament(GO:0005884)
0.1	2.2	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1	7.1	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	0.8	GO:0097651	phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1	3.1	GO:0016592	mediator complex(GO:0016592)
0.1	12.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	1.0	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.1	1.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	4.1	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	0.4	GO:0005903	brush border(GO:0005903) brush border membrane(GO:0031526)
0.0	10.1	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	1.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	4.9	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	63.0	GO:0005576	extracellular region(GO:0005576)
0.0	1.1	GO:0043596	nuclear replication fork(GO:0043596)
0.0	1.7	GO:0030496	midbody(GO:0030496)
0.0	1.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.4	GO:0060170	ciliary membrane(GO:0060170)
0.0	1.0	GO:0044447	axoneme part(GO:0044447)
0.0	7.0	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	2.2	GO:0005882	intermediate filament(GO:0005882)
0.0	0.7	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.6	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0	0.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	17.9	GO:0005739	mitochondrion(GO:0005739)
0.0	0.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.8	GO:0005930	axoneme(GO:0005930)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	15.0	GO:0004743	pyruvate kinase activity(GO:0004743)
1.8	7.2	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.6	17.5	GO:0035804	structural constituent of egg coat(GO:0035804)
1.4	2.8	GO:0004127	cytidylate kinase activity(GO:0004127)
1.4	4.1	GO:0003721	telomerase RNA reverse transcriptase activity(GO:0003721)
1.3	8.8	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
1.1	3.4	GO:0016713	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.1	14.1	GO:0004017	adenylate kinase activity(GO:0004017)
1.1	6.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.9	5.5	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.9	6.9	GO:0001217	bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.8	2.4	GO:0048030	disaccharide binding(GO:0048030)
0.8	4.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.8	0.8	GO:0031543	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.7	5.7	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.7	3.5	GO:0047192	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.7	8.8	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.6	5.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6	3.8	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.6	1.7	GO:0031835	neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.6	6.4	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.5	5.4	GO:0031433	telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.5	15.1	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5	8.0	GO:0030544	Hsp70 protein binding(GO:0030544)
0.5	1.6	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.5	3.5	GO:0034632	retinol transporter activity(GO:0034632)
0.5	3.8	GO:0004100	chitin synthase activity(GO:0004100)
0.4	3.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.4	2.2	GO:0004408	holocytochrome-c synthase activity(GO:0004408)
0.4	5.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.4	1.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.4	4.6	GO:0004046	aminoacylase activity(GO:0004046)
0.4	3.6	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.4	11.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.4	1.6	GO:0070513	death domain binding(GO:0070513)
0.4	2.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4	1.1	GO:0070051	fibrinogen binding(GO:0070051)
0.4	17.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.4	2.6	GO:0004962	endothelin receptor activity(GO:0004962)
0.4	6.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.4	3.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.4	2.9	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.3	2.4	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.3	1.7	GO:0070644	vitamin D response element binding(GO:0070644)
0.3	4.9	GO:2001069	glycogen binding(GO:2001069)
0.3	5.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	1.8	GO:0008142	oxysterol binding(GO:0008142)
0.3	2.1	GO:0031779	melanocortin receptor binding(GO:0031779)
0.3	4.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.3	1.6	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.3	2.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3	1.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3	1.3	GO:0035197	siRNA binding(GO:0035197)
0.2	3.0	GO:0031720	haptoglobin binding(GO:0031720)
0.2	1.2	GO:0098634	C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2	5.7	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	0.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2	0.9	GO:0008459	chondroitin 6-sulfotransferase activity(GO:0008459)
0.2	1.5	GO:0070888	E-box binding(GO:0070888)
0.2	4.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	3.5	GO:0098882	structural constituent of presynaptic active zone(GO:0098882)
0.2	1.6	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.2	1.0	GO:0038132	neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.2	1.5	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.2	3.0	GO:0015377	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2	0.6	GO:0071532	ankyrin repeat binding(GO:0071532)
0.2	2.4	GO:0005223	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2	2.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2	2.9	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	11.3	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.2	4.3	GO:0004623	phospholipase A2 activity(GO:0004623)
0.2	2.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.2	1.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2	2.4	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.2	31.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	5.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2	1.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	2.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.8	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	8.9	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1	1.1	GO:0034452	dynactin binding(GO:0034452)
0.1	6.9	GO:0031491	nucleosome binding(GO:0031491)
0.1	1.0	GO:0004849	uridine kinase activity(GO:0004849)
0.1	2.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	6.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	1.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	5.0	GO:0019957	chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.1	2.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.4	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.1	1.1	GO:0004096	catalase activity(GO:0004096)
0.1	0.5	GO:0003884	D-amino-acid oxidase activity(GO:0003884)
0.1	1.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	2.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.1	8.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	3.0	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	0.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	1.9	GO:0031729	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1	0.8	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	1.8	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	1.5	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.3	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	15.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.2	GO:0008422	beta-glucosidase activity(GO:0008422)
0.1	2.7	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	2.5	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	0.8	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1	1.3	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.8	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	1.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.1	1.1	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	1.3	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	2.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	2.4	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.1	29.6	GO:0051015	actin filament binding(GO:0051015)
0.1	4.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	1.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	16.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	1.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1	1.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	1.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.8	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	1.8	GO:0004016	adenylate cyclase activity(GO:0004016)
0.1	1.3	GO:0030515	snoRNA binding(GO:0030515)
0.1	1.3	GO:0004875	complement receptor activity(GO:0004875)
0.1	5.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	0.4	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.8	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	7.7	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	0.2	GO:0031151	histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1	1.3	GO:0008236	serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.1	1.9	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	6.4	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	6.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.3	GO:0005112	Notch binding(GO:0005112)
0.1	5.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.1	GO:0005178	integrin binding(GO:0005178)
0.0	1.0	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	2.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	1.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.7	GO:0005123	death receptor binding(GO:0005123)
0.0	0.5	GO:0004568	chitinase activity(GO:0004568)
0.0	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	1.1	GO:0019210	protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0	0.2	GO:0052905	tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0	8.0	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	5.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	9.2	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.2	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0	2.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.6	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.5	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	1.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.6	GO:0004601	peroxidase activity(GO:0004601)
0.0	1.7	GO:0004175	endopeptidase activity(GO:0004175)
0.0	1.0	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.6	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	1.5	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.7	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	1.1	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	2.1	GO:0042803	protein homodimerization activity(GO:0042803)
0.0	0.8	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	3.5	GO:0060090	binding, bridging(GO:0060090)
0.0	1.1	GO:0015485	cholesterol binding(GO:0015485)
0.0	8.9	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	1.3	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	0.9	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	2.7	GO:0005125	cytokine activity(GO:0005125)
0.0	1.0	GO:0046332	SMAD binding(GO:0046332)
0.0	1.4	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	14.8	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	14.5	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.4	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.2	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	1.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	3.8	GO:0061630	ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	15.6	NABA COLLAGENS	Genes encoding collagen proteins
0.4	14.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.4	4.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	8.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.3	12.1	PID PLK1 PATHWAY	PLK1 signaling events
0.3	3.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	2.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	13.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	9.2	PID P73PATHWAY	p73 transcription factor network
0.1	3.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	2.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	2.0	PID MYC PATHWAY	C-MYC pathway
0.1	3.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	1.6	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	1.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	1.6	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	0.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	1.7	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	1.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	5.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	3.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	14.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4	3.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.4	3.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.4	4.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	4.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4	3.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.4	1.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	2.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	5.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	4.7	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	15.6	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.3	8.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	6.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2	12.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	3.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.2	1.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.2	1.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	3.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	2.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	1.8	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	11.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	2.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	2.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	2.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	3.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	1.7	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	0.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	0.8	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	1.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	5.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	0.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	4.4	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	2.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.6	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	1.0	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.1	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	2.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	2.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes

Results for cux2b

Z-value: 1.31

Motif logo

Transcription factors associated with cux2b

Activity-expression correlation:

Activity profile of cux2b motif

Sorted Z-values of cux2b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of cux2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: