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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for ctcf

Z-value: 1.28

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)
ENSDARG00000113285 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr11_v1_chr18_+_22285992_222860290.422.5e-05Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_2886937 10.83 ENSDART00000063533
aquaporin 12
chr15_+_47525073 10.22 ENSDART00000067583
SID1 transmembrane family, member 2
chr4_-_17409533 9.24 ENSDART00000011943
phenylalanine hydroxylase
chr20_-_30931139 8.18 ENSDART00000006778
ENSDART00000146376
acetyl-CoA acetyltransferase 2
chr16_+_11558868 8.00 ENSDART00000112497
ENSDART00000180445
zgc:198329
chr9_+_21148318 7.46 ENSDART00000035428
hydroxyacid oxidase 2 (long chain)
chr6_-_42388608 7.06 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr21_-_19918286 6.72 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr13_+_1369003 6.31 ENSDART00000146082
interferon gamma receptor 1
chr8_-_38317914 6.31 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr6_-_27139396 6.11 ENSDART00000055848
zgc:103559
chr24_-_8887825 6.09 ENSDART00000066781
ELOVL fatty acid elongase 2
chr17_+_30894431 5.93 ENSDART00000127996
delta(4)-desaturase, sphingolipid 2
chr2_-_37883256 5.86 ENSDART00000035685
hexose-binding lectin 4
chr9_-_48736388 5.76 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr9_-_34269066 5.41 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr16_+_11585576 5.37 ENSDART00000172967
si:dkey-11o1.6
chr3_+_14641962 5.37 ENSDART00000091070
zgc:158403
chr23_-_13875252 5.10 ENSDART00000104834
ENSDART00000193807
glucose-6-phosphate dehydrogenase
chr22_+_5135884 5.08 ENSDART00000141276
myeloid-derived growth factor
chr13_-_42306348 5.03 ENSDART00000003706
kynurenine 3-monooxygenase
chr12_+_31783066 4.76 ENSDART00000105584
leucine rich repeat containing 59
chr12_-_4220713 4.67 ENSDART00000129427
vitamin K epoxide reductase complex, subunit 1
chr19_+_20785724 4.29 ENSDART00000038942
ADNP homeobox 2b
chr16_+_11573471 4.24 ENSDART00000145858
si:dkey-11o1.2
chr21_+_15713097 4.08 ENSDART00000015841
glutathione S-transferase theta 1b
chr9_-_48700806 4.01 ENSDART00000026210
retinol dehydrogenase 1
chr2_+_22659787 3.90 ENSDART00000043956
zgc:161973
chr2_+_11028923 3.87 ENSDART00000076725
acyl-CoA thioesterase 11a
chr19_-_33274978 3.83 ENSDART00000020301
ENSDART00000114714
family with sequence similarity 92, member A1
chr3_+_25849560 3.73 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr6_-_37749711 3.72 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr2_-_42492445 3.71 ENSDART00000139929
extended synaptotagmin-like protein 2a
chr9_+_21843915 3.66 ENSDART00000101977
potassium channel tetramerisation domain containing 12.1
chr5_-_31773208 3.61 ENSDART00000137556
ENSDART00000122066
family with sequence similarity 102, member Ab
chr24_-_17400143 3.50 ENSDART00000134947
cullin 1b
chr21_+_6114709 3.43 ENSDART00000065858
folylpolyglutamate synthase
chr1_-_46663997 3.37 ENSDART00000134450
emopamil binding protein-like
chr6_-_35046735 3.34 ENSDART00000143649
UDP-N-acetylglucosamine pyrophosphorylase 1
chr12_-_7639120 3.34 ENSDART00000126712
ENSDART00000126219
coiled-coil domain containing 6b
chr22_-_20403194 3.29 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr9_-_29643628 3.28 ENSDART00000101177
SPRY domain containing 7b
chr2_+_3823813 3.28 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr13_+_35765317 3.23 ENSDART00000100156
ENSDART00000167650
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr21_+_6114305 3.19 ENSDART00000141607
folylpolyglutamate synthase
chr9_-_11263228 3.18 ENSDART00000113847
chondroitin polymerizing factor a
chr8_+_47099033 3.14 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr19_+_18903533 3.11 ENSDART00000157523
ENSDART00000166562
solute carrier family 39 (zinc transporter), member 7
chr7_+_52154215 3.10 ENSDART00000098712
zgc:77041
chr13_-_46429220 3.07 ENSDART00000149125
ENSDART00000098269
ENSDART00000150061
ENSDART00000080916
fibroblast growth factor receptor 2
chr1_+_19849168 3.06 ENSDART00000111454
si:dkey-82j4.2
chr19_-_3886991 3.01 ENSDART00000162085
thyroid hormone receptor associated protein 3b
chr3_-_45777226 3.00 ENSDART00000192849
H3 histone, family 3B.1
chr12_-_17492852 3.00 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
multiple inositol-polyphosphate phosphatase 1b
chr21_+_43702016 2.93 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr9_-_41507712 2.87 ENSDART00000135821
major facilitator superfamily domain containing 6b
chr10_+_2842923 2.86 ENSDART00000181895
YKT6 v-SNARE homolog (S. cerevisiae)
chr11_-_41853874 2.84 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr6_+_45934682 2.84 ENSDART00000103489
centromere protein S
chr7_+_34236238 2.84 ENSDART00000052474
timeless interacting protein
chr2_+_23701613 2.80 ENSDART00000047073
oxidative stress responsive 1a
chr24_-_13349802 2.79 ENSDART00000164729
telomeric repeat binding factor (NIMA-interacting) 1
chr1_-_24255149 2.77 ENSDART00000146960
LPS-responsive vesicle trafficking, beach and anchor containing
chr13_-_35765028 2.77 ENSDART00000157391
endoplasmic reticulum lectin 1
chr16_-_31686602 2.76 ENSDART00000170357
complement component 1, s subcomponent
chr17_+_33158350 2.72 ENSDART00000104476
sorting nexin 9a
chr12_+_19976400 2.72 ENSDART00000153177
MKL/myocardin-like 2a
chr13_-_33822550 2.69 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr6_+_60125033 2.67 ENSDART00000148557
ENSDART00000008224
aurora kinase A
chr1_+_40613297 2.66 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr19_-_1947403 2.64 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr12_-_31726748 2.63 ENSDART00000153174
serine/arginine-rich splicing factor 2a
chr21_-_23331619 2.60 ENSDART00000007806
zinc finger and BTB domain containing 16a
chr1_+_55752593 2.59 ENSDART00000108838
ENSDART00000134770
trans-2,3-enoyl-CoA reductase b
chr24_-_38644937 2.58 ENSDART00000170194
solute carrier family 6, member 16b
chr24_-_13349464 2.57 ENSDART00000134482
ENSDART00000139212
telomeric repeat binding factor (NIMA-interacting) 1
chr19_+_24068223 2.54 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr8_-_34427364 2.42 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
GTPase activating protein and VPS9 domains 1
chr5_+_58687541 2.41 ENSDART00000083015
ENSDART00000181902
coiled-coil domain containing 84
chr13_+_9819194 2.41 ENSDART00000091595
family with sequence similarity 45, member A
chr11_+_22623284 2.40 ENSDART00000111850
si:ch211-86h15.1
chr14_+_31473866 2.40 ENSDART00000173088
coiled-coil domain containing 160
chr21_-_32462856 2.37 ENSDART00000147318
zgc:123105
chr19_-_3896514 2.36 ENSDART00000161346
si:ch73-281i18.3
chr5_-_1869982 2.32 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr9_+_29985010 2.32 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr2_-_20666920 2.29 ENSDART00000143437
ENSDART00000114546
ENSDART00000136113
ENSDART00000179247
dual specificity phosphatase 12
chr9_+_22929675 2.29 ENSDART00000061299
translin
chr7_+_13995792 2.28 ENSDART00000091470
furin (paired basic amino acid cleaving enzyme) a
chr10_-_40826657 2.26 ENSDART00000076304
proliferating cell nuclear antigen
chr5_+_61941610 2.23 ENSDART00000168808
si:dkeyp-117b8.4
chr5_-_26764298 2.21 ENSDART00000189373
ring finger protein 181
chr18_+_35229115 2.18 ENSDART00000129624
ENSDART00000184596
transforming growth factor beta regulator 1
chr3_+_31093455 2.15 ENSDART00000153074
si:dkey-66i24.9
chr16_+_11623956 2.14 ENSDART00000137788
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr19_-_3925801 2.12 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
chr8_+_26007988 2.10 ENSDART00000193948
ENSDART00000058100
xeroderma pigmentosum, complementation group C
chr2_+_57149002 2.07 ENSDART00000168497
eukaryotic translation elongation factor 2b
chr7_-_71384391 2.06 ENSDART00000112841
coiled-coil domain containing 149a
chr24_-_17400472 2.06 ENSDART00000024691
cullin 1b
chr16_-_32672883 2.03 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
PNN-interacting serine/arginine-rich protein
chr5_+_41496490 2.02 ENSDART00000039369
Fanconi anemia, complementation group G
chr5_-_58832332 2.01 ENSDART00000161230
Rho guanine nucleotide exchange factor (GEF) 12b
chr6_+_47846366 2.01 ENSDART00000064842
peptidyl arginine deiminase, type II
chr5_+_20319519 1.93 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr16_-_14587332 1.91 ENSDART00000012479
DNA replication and sister chromatid cohesion 1
chr4_-_75158035 1.88 ENSDART00000174353

chr3_-_33417826 1.87 ENSDART00000084284
ABI family, member 3a
chr3_+_36671585 1.87 ENSDART00000159033
nudE neurodevelopment protein 1
chr1_-_56948694 1.86 ENSDART00000152597
si:ch211-1f22.1
chr5_+_57320113 1.85 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr10_-_35186310 1.81 ENSDART00000127805
POM121 transmembrane nucleoporin
chr19_+_1688727 1.80 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr9_-_11655031 1.75 ENSDART00000044314
integrin, alpha V
chr12_-_18898413 1.74 ENSDART00000181281
ENSDART00000121866
desumoylating isopeptidase 1b
chr2_+_54482603 1.74 ENSDART00000130977
ENSDART00000183090
microtubule crosslinking factor 1
chr8_+_42917515 1.74 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr5_-_9948497 1.74 ENSDART00000183196
torsin family 4, member Ab
chr8_-_11202378 1.72 ENSDART00000147817
ENSDART00000174039
family with sequence similarity 208, member B
chr15_-_43978141 1.71 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr16_+_40340222 1.71 ENSDART00000190631
methyltransferase like 6
chr8_+_19621511 1.69 ENSDART00000017128
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr25_+_8921425 1.69 ENSDART00000128591
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr8_-_17184482 1.66 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr1_+_45958904 1.65 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr9_-_12594759 1.64 ENSDART00000021266
transformer 2 beta homolog
chr9_+_35832294 1.62 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
chr2_+_43204919 1.61 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr22_+_20135443 1.60 ENSDART00000143641
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr14_-_31715373 1.60 ENSDART00000127303
ENSDART00000173274
ENSDART00000173435
ENSDART00000172876
ENSDART00000173036
MAP7 domain containing 3
chr1_-_45577980 1.59 ENSDART00000160961
activating transcription factor 7 interacting protein
chr22_-_718615 1.56 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr12_-_999762 1.55 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
methyltransferase like 9
chr17_-_25303486 1.53 ENSDART00000162235
peptidylprolyl isomerase E (cyclophilin E)
chr16_+_40340523 1.53 ENSDART00000102571
methyltransferase like 6
chr3_-_37148594 1.51 ENSDART00000140855
MLX, MAX dimerization protein
chr15_+_17441734 1.51 ENSDART00000153729
sorting nexin 19b
chr15_+_41815703 1.51 ENSDART00000059508
2-phosphoxylose phosphatase 1
chr2_-_40135942 1.50 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr14_-_45595711 1.50 ENSDART00000074038
SCY1-like, kinase-like 1
chr25_-_35963158 1.49 ENSDART00000153612
sorting nexin 20
chr3_+_22057109 1.48 ENSDART00000153709
KAT8 regulatory NSL complex subunit 1b
chr15_-_26887028 1.48 ENSDART00000156292
si:dkey-243i1.1
chr16_+_23799622 1.47 ENSDART00000046922
RAB13, member RAS oncogene family
chr15_+_6786757 1.46 ENSDART00000013278
sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
chr8_+_36983559 1.44 ENSDART00000127053
lysine (K)-specific demethylase 5C
chr16_+_11834516 1.44 ENSDART00000146611
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr5_+_31036911 1.44 ENSDART00000141463
ENSDART00000162121
zinc finger, ZZ-type with EF hand domain 1
chr7_+_29080684 1.43 ENSDART00000173709
ENSDART00000173576
ACD, shelterin complex subunit and telomerase recruitment factor
chr3_+_37790351 1.42 ENSDART00000151506
si:dkey-260c8.8
chr13_+_13033424 1.41 ENSDART00000159441
leucine zipper-EF-hand containing transmembrane protein 1
chr5_+_54497475 1.40 ENSDART00000158149
ENSDART00000163968
ENSDART00000160446
transmembrane protein 203
chr21_+_17005737 1.39 ENSDART00000101246
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr8_+_19621731 1.38 ENSDART00000144667
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr18_-_14677936 1.38 ENSDART00000111995
si:dkey-238o13.4
chr10_+_11355841 1.37 ENSDART00000193067
ENSDART00000064215
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr16_+_28881235 1.35 ENSDART00000146525
chromatin target of PRMT1b
chr19_-_3906369 1.35 ENSDART00000160299
ENSDART00000169205
si:ch73-281i18.4
chr2_-_26596794 1.33 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr5_+_55984270 1.29 ENSDART00000047358
ENSDART00000138191
FK506 binding protein 6
chr8_+_23703680 1.28 ENSDART00000141099
ENSDART00000135394
peroxisome proliferator-activated receptor delta b
chr10_+_17681074 1.27 ENSDART00000057500
developmentally regulated GTP binding protein 1
chr4_+_12931763 1.26 ENSDART00000016382
wnt inhibitory factor 1
chr7_+_66634167 1.26 ENSDART00000027616
eukaryotic translation initiation factor 4, gamma 2a
chr6_+_48041759 1.26 ENSDART00000140086
si:dkey-92f12.2
chr3_-_30248277 1.25 ENSDART00000133516
ENSDART00000077029
ER membrane protein complex subunit 10
chr13_+_13033837 1.21 ENSDART00000079558
leucine zipper-EF-hand containing transmembrane protein 1
chr9_+_38043337 1.21 ENSDART00000022574
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr24_+_26329018 1.20 ENSDART00000145752
myoneurin
chr24_-_10897511 1.20 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
family with sequence similarity 49, member Bb
chr15_+_31911989 1.20 ENSDART00000111472
breast cancer 2, early onset
chr1_+_12049229 1.18 ENSDART00000103403
ENSDART00000137697
store-operated calcium entry-associated regulatory factor
chr21_+_26539157 1.18 ENSDART00000021121
syntaxin 5A, like
chr16_-_8132742 1.16 ENSDART00000104323
SNF related kinase a
chr13_-_14908999 1.15 ENSDART00000112771
adaptor-related protein complex 5, sigma 1 subunit
chr25_+_5972690 1.14 ENSDART00000067517
si:ch211-11i22.4
chr12_-_5418340 1.14 ENSDART00000028043
NOC3-like DNA replication regulator
chr8_+_25900049 1.13 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
ras homolog gene family, member Ab
chr13_-_36761379 1.13 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr19_+_20274944 1.11 ENSDART00000151237
oxidoreductase NAD-binding domain containing 1
chr15_-_4967302 1.11 ENSDART00000101992
lipoyl(octanoyl) transferase 2
chr1_+_17527342 1.06 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
caspase 3, apoptosis-related cysteine peptidase a
chr5_+_35955209 1.05 ENSDART00000074630
zgc:103697
chr8_+_37749263 1.04 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr21_+_25120546 1.04 ENSDART00000149507
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr24_+_26328787 1.03 ENSDART00000003884
myoneurin
chr12_+_46967789 1.02 ENSDART00000114866
ornithine aminotransferase
chr5_+_32076109 1.02 ENSDART00000051357
ENSDART00000144510
zinc finger, matrin-type 5
chr19_-_3916075 1.01 ENSDART00000161799
si:ch73-281i18.7
chr12_+_8569685 0.98 ENSDART00000031676
nuclear receptor binding factor 2b
chr1_+_26676758 0.97 ENSDART00000152299
si:dkey-25o16.4
chr18_+_41542542 0.96 ENSDART00000087445
TSEN34 tRNA splicing endonuclease subunit
chr2_+_42724404 0.96 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr19_+_14113886 0.96 ENSDART00000169343
keratinocyte differentiation factor 1b
chr4_-_18512550 0.95 ENSDART00000045639
RAD50 interactor 1
chr18_-_40753583 0.94 ENSDART00000026767
v-akt murine thymoma viral oncogene homolog 2
chr25_+_24250247 0.93 ENSDART00000064646
transmembrane protein 86A
chr5_+_55934129 0.93 ENSDART00000050969
transmembrane protein 150Ab
chr5_-_32396929 0.93 ENSDART00000023977
F-box and WD repeat domain containing 2
chr21_+_25533908 0.92 ENSDART00000185225
NLR family, CARD domain containing 3-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
2.0 6.1 GO:0006145 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
1.7 6.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
1.6 4.7 GO:0042373 vitamin K metabolic process(GO:0042373)
1.0 7.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
1.0 5.0 GO:0043420 anthranilate metabolic process(GO:0043420)
1.0 2.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 2.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.9 2.6 GO:0034214 protein hexamerization(GO:0034214)
0.8 9.2 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.8 9.8 GO:0042572 retinol metabolic process(GO:0042572)
0.7 2.9 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.7 3.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.6 1.9 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.6 1.7 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.6 2.8 GO:0043111 replication fork arrest(GO:0043111)
0.6 2.3 GO:0006272 leading strand elongation(GO:0006272)
0.6 1.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.5 1.5 GO:0043388 negative regulation of gliogenesis(GO:0014014) positive regulation of DNA binding(GO:0043388) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.5 1.4 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.5 1.4 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.4 3.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.4 5.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.4 5.9 GO:0034311 diol metabolic process(GO:0034311)
0.4 2.5 GO:0016559 peroxisome fission(GO:0016559)
0.4 1.6 GO:1902414 establishment of centrosome localization(GO:0051660) protein localization to cell junction(GO:1902414)
0.4 2.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.4 2.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.4 1.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.3 1.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 1.9 GO:0007100 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.3 5.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.3 1.5 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.3 6.3 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.3 5.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 1.8 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.3 6.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 3.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 5.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.2 0.9 GO:0046324 regulation of glucose import(GO:0046324)
0.2 1.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.7 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 3.7 GO:0015693 magnesium ion transport(GO:0015693)
0.2 10.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.2 2.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 1.5 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.2 5.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.2 3.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 0.6 GO:0071514 genetic imprinting(GO:0071514)
0.2 8.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 2.6 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 3.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 1.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 1.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 2.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.9 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.2 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 2.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 2.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 4.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 3.7 GO:0021986 habenula development(GO:0021986)
0.1 2.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 12.5 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.1 1.0 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 4.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.2 GO:0007530 sex determination(GO:0007530)
0.1 4.8 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.7 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 2.1 GO:0006298 mismatch repair(GO:0006298)
0.1 2.8 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.9 GO:0090148 membrane fission(GO:0090148)
0.1 3.2 GO:0051298 centrosome duplication(GO:0051298)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 2.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.6 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.7 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 3.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 3.4 GO:0006414 translational elongation(GO:0006414)
0.1 1.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.7 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.8 GO:0031638 zymogen activation(GO:0031638)
0.0 4.6 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.9 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.3 GO:0048794 swim bladder development(GO:0048794)
0.0 0.4 GO:0035283 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 1.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.2 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 2.1 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.0 2.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.4 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 3.4 GO:0016125 sterol metabolic process(GO:0016125)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 1.9 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.4 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 3.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 1.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 4.9 GO:0008380 RNA splicing(GO:0008380)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.0 GO:0015074 DNA integration(GO:0015074)
0.0 0.9 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 3.0 GO:0032259 methylation(GO:0032259)
0.0 1.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.7 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.8 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.1 GO:0005784 Sec61 translocon complex(GO:0005784)
1.0 3.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.7 2.9 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.6 2.8 GO:0031298 replication fork protection complex(GO:0031298)
0.5 2.7 GO:0031415 NatA complex(GO:0031415)
0.5 1.5 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.4 2.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 4.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 6.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 2.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 6.8 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.2 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.6 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.2 0.5 GO:0034709 methylosome(GO:0034709)
0.2 2.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 3.8 GO:0005771 multivesicular body(GO:0005771)
0.1 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 6.3 GO:0031941 filamentous actin(GO:0031941)
0.1 1.4 GO:0030904 retromer complex(GO:0030904)
0.1 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.5 GO:0044545 NSL complex(GO:0044545)
0.1 5.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 1.9 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 2.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 9.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 11.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 5.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 3.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 13.0 GO:0000323 lytic vacuole(GO:0000323)
0.0 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 22.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 6.2 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 2.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.7 GO:0005938 cell cortex(GO:0005938)
0.0 4.4 GO:0005730 nucleolus(GO:0005730)
0.0 5.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0044297 cell body(GO:0044297)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.8 5.4 GO:0071532 ankyrin repeat binding(GO:0071532)
1.7 5.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.5 6.1 GO:0050897 cobalt ion binding(GO:0050897)
1.2 9.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.1 17.3 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
1.0 9.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.7 3.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.7 3.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.7 2.6 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.5 3.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.5 2.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 5.0 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.5 3.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 1.4 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.4 6.7 GO:2001069 glycogen binding(GO:2001069)
0.4 3.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 2.7 GO:0035173 histone kinase activity(GO:0035173)
0.4 1.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.4 3.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 7.5 GO:0010181 FMN binding(GO:0010181)
0.3 3.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 6.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 6.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 3.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 2.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 4.7 GO:0048038 quinone binding(GO:0048038)
0.2 6.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 2.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 2.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.0 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 3.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 1.3 GO:0032977 membrane insertase activity(GO:0032977)
0.2 1.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 3.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.6 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 4.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.9 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 1.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 4.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 3.7 GO:0043022 ribosome binding(GO:0043022)
0.1 5.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 6.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 7.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 2.2 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 2.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 2.6 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 6.6 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 3.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 7.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 4.0 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 3.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.0 GO:0003682 chromatin binding(GO:0003682)
0.0 1.9 GO:0016820 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 3.0 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 4.6 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 4.3 PID BARD1 PATHWAY BARD1 signaling events
0.2 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 9.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.7 PID AURORA A PATHWAY Aurora A signaling
0.1 4.0 PID ATR PATHWAY ATR signaling pathway
0.1 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.8 6.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.5 4.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5 6.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 5.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.4 3.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.2 3.9 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 3.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 5.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 1.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 2.9 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 3.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 8.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 10.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.7 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 4.4 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening