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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for creb3l1
Z-value: 0.90
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Transcription factors associated with creb3l1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| creb3l1 | dr11_v1_chr7_+_38897836_38897836 | -0.15 | 1.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_2886937 Show fit | 17.27 |
ENSDART00000063533
|
aquaporin 12 |
|
| chr1_-_7930679 Show fit | 8.10 |
ENSDART00000146090
|
si:dkey-79f11.10 |
|
| chr18_-_34549721 Show fit | 8.09 |
ENSDART00000137101
ENSDART00000021880 |
signal sequence receptor, gamma |
|
| chr21_+_10702031 Show fit | 8.05 |
ENSDART00000102304
|
lectin, mannose-binding, 1 |
|
| chr21_+_10701834 Show fit | 7.66 |
ENSDART00000192473
|
lectin, mannose-binding, 1 |
|
| chr16_+_19637384 Show fit | 7.28 |
ENSDART00000184773
ENSDART00000191895 ENSDART00000182020 ENSDART00000135359 |
metastasis associated in colon cancer 1 |
|
| chr18_-_7031409 Show fit | 5.81 |
ENSDART00000148485
ENSDART00000005405 |
calumenin b |
|
| chr23_-_31266586 Show fit | 5.49 |
ENSDART00000139746
|
si:dkey-261l7.2 |
|
| chr6_+_13506841 Show fit | 5.44 |
ENSDART00000032331
|
GDP-mannose pyrophosphorylase Ab |
|
| chr14_-_45464112 Show fit | 5.43 |
ENSDART00000173209
|
EH-domain containing 1a |
Network of associatons between targets according to the STRING database.
First level regulatory network of creb3l1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 33.0 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.1 | 9.7 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.5 | 8.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 8.1 | GO:0006955 | immune response(GO:0006955) |
| 0.0 | 7.3 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.9 | 5.4 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 5.4 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 5.2 | GO:0006637 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.4 | 5.1 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 1.2 | 4.8 | GO:0051645 | Golgi localization(GO:0051645) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 27.0 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 1.4 | 9.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.6 | 9.5 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.2 | 9.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 7.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 5.3 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.0 | 3.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 3.0 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.3 | 2.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 2.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 15.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 13.4 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 8.4 | GO:0000149 | SNARE binding(GO:0000149) |
| 1.4 | 5.4 | GO:0008905 | mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905) |
| 0.2 | 5.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 1.6 | 4.7 | GO:0004779 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.1 | 4.2 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.7 | 4.0 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.2 | 3.6 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.1 | 3.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 15.7 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 4.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 3.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 3.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 3.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 2.7 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 2.7 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 20.9 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 8.1 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 3.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 2.7 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.2 | 2.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 2.2 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.3 | 1.8 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.2 | 1.7 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 1.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |