ISMARA results: clocka+clockb+npas2

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for clocka+clockb+npas2

Z-value: 1.88

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Transcription factors associated with clocka+clockb+npas2

Gene Symbol	Gene ID	Gene Info
clockb NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000003631	clock circadian regulator b
clocka NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000011703	clock circadian regulator a
npas2 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000016536	neuronal PAS domain protein 2
npas2 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000116993	neuronal PAS domain protein 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
clocka	dr11_v1_chr20_+_22067337_22067337	-0.66	5.7e-13	Click!
clockb	dr11_v1_chr1_+_19434198_19434198	-0.49	4.9e-07	Click!
npas2	dr11_v1_chr5_+_22791686_22791686	-0.37	2.6e-04	Click!

Activity profile of clocka+clockb+npas2 motif

Sorted Z-values of clocka+clockb+npas2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_43119698 Show fit	22.88	ENSDART00000167847 ENSDART00000186962 ENSDART00000187305	eef1a1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation elongation factor 1 alpha 1, like 1
chr14_+_22076596 Show fit	22.76	ENSDART00000106147 ENSDART00000100278 ENSDART00000131489	slc43a1a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 43 (amino acid system L transporter), member 1a
chr21_+_11969603 Show fit	21.18	ENSDART00000142247 ENSDART00000140652	mlnl NCBI UniProt ZFIN ENSEMBL Google Show fit	motilin-like
chr10_+_22034477 Show fit	18.76	ENSDART00000133304 ENSDART00000134189 ENSDART00000021240 ENSDART00000100526	npm1a NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleophosmin 1a
chr19_-_47555956 Show fit	17.76	ENSDART00000114549	actc1a NCBI UniProt ZFIN ENSEMBL Google Show fit	actin, alpha, cardiac muscle 1a
chr20_-_29483514 Show fit	17.13	ENSDART00000062370	actc1a NCBI UniProt ZFIN ENSEMBL Google Show fit	actin, alpha, cardiac muscle 1a
chr24_-_12938922 Show fit	16.26	ENSDART00000024084	pck2 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr22_-_23612854 Show fit	11.93	ENSDART00000165885	cfhl5 NCBI UniProt ZFIN ENSEMBL Google Show fit	complement factor H like 5
chr20_+_10544100 Show fit	11.78	ENSDART00000113927	serpina1 NCBI UniProt ZFIN ENSEMBL Google Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr16_-_26537103 Show fit	11.73	ENSDART00000134908 ENSDART00000008152	sgk2b NCBI UniProt ZFIN ENSEMBL Google Show fit	serum/glucocorticoid regulated kinase 2b
chr21_-_20765338 Show fit	11.66	ENSDART00000135940	ghrb NCBI UniProt ZFIN ENSEMBL Google Show fit	growth hormone receptor b
chr9_+_20781047 Show fit	11.33	ENSDART00000139174	fam46c NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 46, member C
chr16_-_31919568 Show fit	10.87	ENSDART00000027364	rbfox1l NCBI UniProt ZFIN ENSEMBL Google Show fit	RNA binding fox-1 homolog 1, like
chr11_-_16975190 Show fit	10.63	ENSDART00000122222	suclg2 NCBI UniProt ZFIN ENSEMBL Google Show fit	succinate-CoA ligase, GDP-forming, beta subunit
chr10_+_17026870 Show fit	10.59	ENSDART00000184529 ENSDART00000157480	CR855996.2 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr3_-_18805225 Show fit	9.67	ENSDART00000133471 ENSDART00000131758	msrb1a NCBI UniProt ZFIN ENSEMBL Google Show fit	methionine sulfoxide reductase B1a
chr10_-_322769 Show fit	9.58	ENSDART00000165244	akt2l NCBI UniProt ZFIN ENSEMBL Google Show fit	v-akt murine thymoma viral oncogene homolog 2, like
chr5_+_38462121 Show fit	9.38	ENSDART00000144425	gltpd2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycolipid transfer protein domain containing 2
chr23_+_25292147 Show fit	9.35	ENSDART00000131486	pa2g4b NCBI UniProt ZFIN ENSEMBL Google Show fit	proliferation-associated 2G4, b
chr5_-_1963498 Show fit	9.19	ENSDART00000073462	rplp0 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein, large, P0
chr7_+_6652967 Show fit	9.18	ENSDART00000102681	pnp5a NCBI UniProt ZFIN ENSEMBL Google Show fit	purine nucleoside phosphorylase 5a
chr2_-_42375275 Show fit	9.14	ENSDART00000026339	gtpbp4 NCBI UniProt ZFIN ENSEMBL Google Show fit	GTP binding protein 4
chr5_+_19337108 Show fit	9.10	ENSDART00000089078	acacb NCBI UniProt ZFIN ENSEMBL Google Show fit	acetyl-CoA carboxylase beta
chr3_-_16760923 Show fit	9.06	ENSDART00000055855	aspdh NCBI UniProt ZFIN ENSEMBL Google Show fit	aspartate dehydrogenase domain containing
chr6_+_50451337 Show fit	9.01	ENSDART00000155051	mych NCBI UniProt ZFIN ENSEMBL Google Show fit	myelocytomatosis oncogene homolog
chr17_-_49407091 Show fit	8.87	ENSDART00000021950	mthfd1b NCBI UniProt ZFIN ENSEMBL Google Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr24_-_42090635 Show fit	8.67	ENSDART00000166413	ssr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	signal sequence receptor, alpha
chr6_-_8498908 Show fit	8.57	ENSDART00000149222	pglyrp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	peptidoglycan recognition protein 2
chr11_-_29946927 Show fit	8.50	ENSDART00000165182	zgc:113276 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113276
chr14_+_14836468 Show fit	8.46	ENSDART00000166728	si:dkey-102m7.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-102m7.3
chr18_-_19456269 Show fit	8.30	ENSDART00000060363	rpl4 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L4
chr7_+_67467702 Show fit	8.27	ENSDART00000168460 ENSDART00000170322	rpl13 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L13
chr8_+_26059677 Show fit	8.25	ENSDART00000009178	impdh2 NCBI UniProt ZFIN ENSEMBL Google Show fit	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr11_-_28050559 Show fit	8.13	ENSDART00000136859	ece1 NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin converting enzyme 1
chr11_-_29946640 Show fit	8.11	ENSDART00000079175	zgc:113276 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113276
chr20_-_49704915 Show fit	8.01	ENSDART00000189232	COX7A2 (1 of many) NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome c oxidase subunit 7A2
chr3_-_58798377 Show fit	8.01	ENSDART00000161248	si:ch73-281f12.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-281f12.4
chr18_+_15644559 Show fit	7.97	ENSDART00000061794	nr1h4 NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear receptor subfamily 1, group H, member 4
chr13_-_31370184 Show fit	7.78	ENSDART00000034829	rrp12 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal RNA processing 12 homolog
chr11_-_37995501 Show fit	7.65	ENSDART00000192096	slc41a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 41 (magnesium transporter), member 1
chr22_-_20695237 Show fit	7.62	ENSDART00000112722	org NCBI UniProt ZFIN ENSEMBL Google Show fit	oogenesis-related gene
chr12_+_48390715 Show fit	7.61	ENSDART00000149351	scd NCBI UniProt ZFIN ENSEMBL Google Show fit	stearoyl-CoA desaturase (delta-9-desaturase)
chr13_-_42306348 Show fit	7.61	ENSDART00000003706	kmo NCBI UniProt ZFIN ENSEMBL Google Show fit	kynurenine 3-monooxygenase
chr21_+_43702016 Show fit	7.57	ENSDART00000017176	dkc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	dyskeratosis congenita 1, dyskerin
chr22_+_835728 Show fit	7.56	ENSDART00000003325	dennd2db NCBI UniProt ZFIN ENSEMBL Google Show fit	DENN/MADD domain containing 2Db
chr20_+_25626479 Show fit	7.55	ENSDART00000143883	ppat NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoribosyl pyrophosphate amidotransferase
chr4_+_25607743 Show fit	7.48	ENSDART00000028297	acot14 NCBI UniProt ZFIN ENSEMBL Google Show fit	acyl-CoA thioesterase 14
chr3_+_18398876 Show fit	7.47	ENSDART00000141100 ENSDART00000138107	rps2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein S2
chr2_-_51630555 Show fit	7.43	ENSDART00000171746	pigr NCBI UniProt ZFIN ENSEMBL Google Show fit	polymeric immunoglobulin receptor
chr2_+_37875789 Show fit	7.32	ENSDART00000036318 ENSDART00000127679	cbln13 NCBI UniProt ZFIN ENSEMBL Google Show fit	cerebellin 13
chr24_+_34069675 Show fit	7.28	ENSDART00000143995	si:ch211-190p8.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-190p8.2
chr11_+_3959495 Show fit	7.17	ENSDART00000122953	gnl3 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein-like 3 (nucleolar)
chr6_-_52348562 Show fit	7.14	ENSDART00000142565 ENSDART00000145369 ENSDART00000016890	eif6 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 6
chr9_-_33328948 Show fit	7.12	ENSDART00000006948	rpl8 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L8
chr15_+_32711663 Show fit	7.08	ENSDART00000157854 ENSDART00000167515	postnb NCBI UniProt ZFIN ENSEMBL Google Show fit	periostin, osteoblast specific factor b
chr11_+_29671661 Show fit	7.00	ENSDART00000024318 ENSDART00000165024	rnf207a NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 207a
chr7_-_38644560 Show fit	6.96	ENSDART00000114934	c6ast3 NCBI UniProt ZFIN ENSEMBL Google Show fit	six-cysteine containing astacin protease 3
chr7_+_41812190 Show fit	6.92	ENSDART00000113732 ENSDART00000174137	orc6 NCBI UniProt ZFIN ENSEMBL Google Show fit	origin recognition complex, subunit 6
chr8_-_21372446 Show fit	6.91	ENSDART00000061481 ENSDART00000079293	ela2l NCBI UniProt ZFIN ENSEMBL Google Show fit	elastase 2 like
chr4_-_16824231 Show fit	6.89	ENSDART00000014007	gys2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogen synthase 2
chr14_+_23518110 Show fit	6.86	ENSDART00000112930	si:ch211-221f10.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-221f10.2
chr12_+_30586599 Show fit	6.85	ENSDART00000124920 ENSDART00000126984	nrap NCBI UniProt ZFIN ENSEMBL Google Show fit	nebulin-related anchoring protein
chr4_-_16824556 Show fit	6.84	ENSDART00000165289 ENSDART00000185839	gys2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogen synthase 2
chr19_+_42983613 Show fit	6.81	ENSDART00000033724	fabp3 NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid binding protein 3, muscle and heart
chr21_-_22724980 Show fit	6.79	ENSDART00000035469	c1qa NCBI UniProt ZFIN ENSEMBL Google Show fit	complement component 1, q subcomponent, A chain
chr5_+_13870340 Show fit	6.77	ENSDART00000160690	hk2 NCBI UniProt ZFIN ENSEMBL Google Show fit	hexokinase 2
chr12_+_19384615 Show fit	6.76	ENSDART00000078266	rsl1d1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal L1 domain containing 1
chr5_+_72194444 Show fit	6.73	ENSDART00000165436	ddx54 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr8_+_23213320 Show fit	6.71	ENSDART00000032996 ENSDART00000137536	ppdpfa NCBI UniProt ZFIN ENSEMBL Google Show fit	pancreatic progenitor cell differentiation and proliferation factor a
chr19_+_32166702 Show fit	6.70	ENSDART00000021798	fabp11a NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid binding protein 11a
chr3_+_16229911 Show fit	6.70	ENSDART00000121728	rpl19 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L19
chr16_-_48400639 Show fit	6.68	ENSDART00000159372	eif3ha NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 3, subunit H, a
chr17_+_53156530 Show fit	6.66	ENSDART00000126277 ENSDART00000156774	dph6 NCBI UniProt ZFIN ENSEMBL Google Show fit	diphthamine biosynthesis 6
chr9_-_33329700 Show fit	6.59	ENSDART00000147265 ENSDART00000140039	rpl8 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L8
chr22_+_661711 Show fit	6.56	ENSDART00000113795	elf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_-_58798815 Show fit	6.50	ENSDART00000082920	si:ch73-281f12.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-281f12.4
chr6_+_29305190 Show fit	6.42	ENSDART00000078647	si:ch211-201h21.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-201h21.5
chr7_+_41812817 Show fit	6.39	ENSDART00000174165	orc6 NCBI UniProt ZFIN ENSEMBL Google Show fit	origin recognition complex, subunit 6
chr3_-_3398383 Show fit	6.36	ENSDART00000047865	si:dkey-46g23.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-46g23.2
chr18_+_8917766 Show fit	6.31	ENSDART00000145226	si:ch211-233h19.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-233h19.2
chr21_-_45382112 Show fit	6.27	ENSDART00000151029 ENSDART00000151335 ENSDART00000151687 ENSDART00000075438	cdkn2aipnl NCBI UniProt ZFIN ENSEMBL Google Show fit	CDKN2A interacting protein N-terminal like
chr8_-_18203274 Show fit	6.23	ENSDART00000134078 ENSDART00000180235 ENSDART00000080006 ENSDART00000125418 ENSDART00000142114	elovl8b NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL fatty acid elongase 8b
chr15_+_25635326 Show fit	6.15	ENSDART00000135409 ENSDART00000162240 ENSDART00000052645	tsr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chr7_+_41812636 Show fit	6.09	ENSDART00000174333	orc6 NCBI UniProt ZFIN ENSEMBL Google Show fit	origin recognition complex, subunit 6
chr9_-_11587070 Show fit	6.08	ENSDART00000030995	umps NCBI UniProt ZFIN ENSEMBL Google Show fit	uridine monophosphate synthetase
chr9_-_56231387 Show fit	6.07	ENSDART00000149851	rpl31 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L31
chr22_+_661505 Show fit	6.07	ENSDART00000149460	elf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr9_+_20780813 Show fit	6.07	ENSDART00000142787	fam46c NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 46, member C
chr21_+_26071874 Show fit	6.06	ENSDART00000003001 ENSDART00000146573	rpl23a NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L23a
chr8_-_18203092 Show fit	6.00	ENSDART00000140620	elovl8b NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL fatty acid elongase 8b
chr5_-_42060121 Show fit	6.00	ENSDART00000148021 ENSDART00000147407	cenpv NCBI UniProt ZFIN ENSEMBL Google Show fit	centromere protein V
chr16_-_34195002 Show fit	5.98	ENSDART00000054026	rcc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of chromosome condensation 1
chr3_-_25377163 Show fit	5.96	ENSDART00000055490	kpna2 NCBI UniProt ZFIN ENSEMBL Google Show fit	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr16_+_25245857 Show fit	5.95	ENSDART00000155220	klhl38b NCBI UniProt ZFIN ENSEMBL Google Show fit	kelch-like family member 38b
chr16_-_13388821 Show fit	5.93	ENSDART00000144062	grin2db NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr22_+_29991834 Show fit	5.91	ENSDART00000147728	si:dkey-286j15.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-286j15.3
chr2_+_25839650 Show fit	5.90	ENSDART00000134077 ENSDART00000140804	eif5a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 5A2
chr5_-_32505109 Show fit	5.90	ENSDART00000188219	ntmt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr12_+_47081783 Show fit	5.89	ENSDART00000158568	mtr NCBI UniProt ZFIN ENSEMBL Google Show fit	5-methyltetrahydrofolate-homocysteine methyltransferase
chr8_-_11229523 Show fit	5.89	ENSDART00000002164	unc45b NCBI UniProt ZFIN ENSEMBL Google Show fit	unc-45 myosin chaperone B
chr3_+_1150348 Show fit	5.87	ENSDART00000148524	nol12 NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleolar protein 12
chr10_+_17714866 Show fit	5.86	ENSDART00000039969	slc20a1b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 20 (phosphate transporter), member 1b
chr25_+_28555584 Show fit	5.86	ENSDART00000157046	SLC15A5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-190o6.3
chr14_+_94603 Show fit	5.84	ENSDART00000162480	mcm7 NCBI UniProt ZFIN ENSEMBL Google Show fit	minichromosome maintenance complex component 7
chr7_-_38644287 Show fit	5.83	ENSDART00000182307	c6ast3 NCBI UniProt ZFIN ENSEMBL Google Show fit	six-cysteine containing astacin protease 3
chr16_+_16969060 Show fit	5.81	ENSDART00000182819 ENSDART00000191876	si:ch211-120k19.1 NCBI UniProt ZFIN ENSEMBL Google Show fit rpl18 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-120k19.1 ribosomal protein L18
chr23_+_25291891 Show fit	5.75	ENSDART00000016248	pa2g4b NCBI UniProt ZFIN ENSEMBL Google Show fit	proliferation-associated 2G4, b
chr7_+_69841017 Show fit	5.67	ENSDART00000169107	FO818704.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr4_-_4570475 Show fit	5.62	ENSDART00000184955	rassf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	Ras association (RalGDS/AF-6) domain family member 3
chr13_+_15701849 Show fit	5.61	ENSDART00000003517	trmt61a NCBI UniProt ZFIN ENSEMBL Google Show fit	tRNA methyltransferase 61A
chr5_+_37517800 Show fit	5.58	ENSDART00000048107	FP102018.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA.
chr12_+_466324 Show fit	5.57	ENSDART00000169691	mprip NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin phosphatase Rho interacting protein
chr8_+_44783424 Show fit	5.57	ENSDART00000025875	si:ch1073-459j12.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-459j12.1
chr25_+_19734038 Show fit	5.51	ENSDART00000067354	zgc:101783 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:101783
chr16_+_16968682 Show fit	5.45	ENSDART00000111074	si:ch211-120k19.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-120k19.1
chr15_+_20239141 Show fit	5.42	ENSDART00000101152 ENSDART00000152473	spint2 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine peptidase inhibitor, Kunitz type, 2
chr9_+_24065855 Show fit	5.37	ENSDART00000161468 ENSDART00000171577 ENSDART00000172743 ENSDART00000159324 ENSDART00000079689 ENSDART00000023196 ENSDART00000101577	lrrfip1a NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine rich repeat (in FLII) interacting protein 1a
chr5_-_42059869 Show fit	5.36	ENSDART00000193984	cenpv NCBI UniProt ZFIN ENSEMBL Google Show fit	centromere protein V
chr1_-_52461322 Show fit	5.35	ENSDART00000083836	si:ch211-217k17.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-217k17.7
chr13_-_280827 Show fit	5.28	ENSDART00000144819	slc30a6 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 30 (zinc transporter), member 6
chr22_-_5323482 Show fit	5.25	ENSDART00000145785	s1pr4 NCBI UniProt ZFIN ENSEMBL Google Show fit	sphingosine-1-phosphate receptor 4
chr17_-_51651631 Show fit	5.24	ENSDART00000154699	ccr6b NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) receptor 6b
chr6_-_1187565 Show fit	5.23	ENSDART00000191756	txnrd3 NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin reductase 3
chr3_+_1015867 Show fit	5.21	ENSDART00000109912	si:ch1073-464p5.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-464p5.5
chr25_-_13050959 Show fit	5.19	ENSDART00000169041	ccl35.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 35, duplicate 1
chr1_-_43727418 Show fit	5.18	ENSDART00000133715 ENSDART00000074597 ENSDART00000132542 ENSDART00000181792	bdh2 NCBI UniProt ZFIN ENSEMBL Google Show fit SLC9B2 NCBI UniProt ZFIN ENSEMBL Google Show fit	3-hydroxybutyrate dehydrogenase, type 2 si:dkey-162b23.4
chr23_+_45906137 Show fit	5.07	ENSDART00000159939	abcg2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP-binding cassette, sub-family G (WHITE), member 2a
chr12_-_18898413 Show fit	5.06	ENSDART00000181281 ENSDART00000121866	desi1b NCBI UniProt ZFIN ENSEMBL Google Show fit	desumoylating isopeptidase 1b
chr2_+_25840463 Show fit	5.04	ENSDART00000125178	eif5a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 5A2
chr10_+_8437930 Show fit	5.03	ENSDART00000074553	pptc7b NCBI UniProt ZFIN ENSEMBL Google Show fit	PTC7 protein phosphatase homolog b
chr24_+_36317544 Show fit	5.02	ENSDART00000048640 ENSDART00000156096	pus3 NCBI UniProt ZFIN ENSEMBL Google Show fit	pseudouridylate synthase 3
chr2_-_51512294 Show fit	5.01	ENSDART00000185287	si:ch211-9d9.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-9d9.8
chr2_+_58877162 Show fit	4.97	ENSDART00000122174	CABZ01085658.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr19_-_31035325 Show fit	4.96	ENSDART00000147504	bzw2 NCBI UniProt ZFIN ENSEMBL Google Show fit	basic leucine zipper and W2 domains 2
chr14_-_15739969 Show fit	4.95	ENSDART00000164841 ENSDART00000192635	neurl1b NCBI UniProt ZFIN ENSEMBL Google Show fit	neuralized E3 ubiquitin protein ligase 1B
chr19_-_34117056 Show fit	4.94	ENSDART00000158677	si:dkey-184p18.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-184p18.2
chr6_-_57476465 Show fit	4.93	ENSDART00000128065	ddx27 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr5_-_16475374 Show fit	4.92	ENSDART00000134274 ENSDART00000136004	piwil2 NCBI UniProt ZFIN ENSEMBL Google Show fit	piwi-like RNA-mediated gene silencing 2
chr2_+_25839940 Show fit	4.85	ENSDART00000139927	eif5a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 5A2
chr1_-_9195629 Show fit	4.84	ENSDART00000143587 ENSDART00000192174	ern2 NCBI UniProt ZFIN ENSEMBL Google Show fit	endoplasmic reticulum to nucleus signaling 2
chr12_+_13091842 Show fit	4.81	ENSDART00000185477 ENSDART00000181435 ENSDART00000124799	si:ch211-103b1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-103b1.2
chr14_+_16151636 Show fit	4.81	ENSDART00000159352	polr1a NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) I polypeptide A
chr6_-_1187749 Show fit	4.81	ENSDART00000172544	txnrd3 NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin reductase 3
chr6_-_21189295 Show fit	4.79	ENSDART00000137136	obsl1a NCBI UniProt ZFIN ENSEMBL Google Show fit	obscurin-like 1a
chr11_+_45092866 Show fit	4.76	ENSDART00000163408	si:dkey-93h22.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-93h22.8
chr16_-_38333976 Show fit	4.74	ENSDART00000031895	cdc42se1 NCBI UniProt ZFIN ENSEMBL Google Show fit	CDC42 small effector 1
chr23_+_17417539 Show fit	4.72	ENSDART00000182605	BX649300.2 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr3_-_1387292 Show fit	4.72	ENSDART00000163535	ddx47 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr9_+_23770666 Show fit	4.72	ENSDART00000182493	si:ch211-219a4.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-219a4.3
chr16_-_5844881 Show fit	4.68	ENSDART00000085678	trak1a NCBI UniProt ZFIN ENSEMBL Google Show fit	trafficking protein, kinesin binding 1a
chr16_+_25259313 Show fit	4.66	ENSDART00000058938	fbxo32 NCBI UniProt ZFIN ENSEMBL Google Show fit	F-box protein 32
chr19_-_24555935 Show fit	4.64	ENSDART00000132660 ENSDART00000162801	polr3gla NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) III (DNA directed) polypeptide G like a
chr18_+_44795711 Show fit	4.64	ENSDART00000110229 ENSDART00000188262 ENSDART00000139526	fam118b NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 118, member B
chr19_+_20201254 Show fit	4.62	ENSDART00000010140	igf2bp3 NCBI UniProt ZFIN ENSEMBL Google Show fit	insulin-like growth factor 2 mRNA binding protein 3
chr5_-_33959868 Show fit	4.62	ENSDART00000143652	zgc:63972 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:63972
chr13_+_29238850 Show fit	4.61	ENSDART00000026000	myofl NCBI UniProt ZFIN ENSEMBL Google Show fit	myoferlin like
chr15_-_36533322 Show fit	4.59	ENSDART00000156466 ENSDART00000121755	si:dkey-262k9.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-262k9.4
chr14_+_30774032 Show fit	4.58	ENSDART00000139552	atl3 NCBI UniProt ZFIN ENSEMBL Google Show fit	atlastin 3
chr7_+_32021982 Show fit	4.55	ENSDART00000173848	mettl15 NCBI UniProt ZFIN ENSEMBL Google Show fit	methyltransferase like 15
chr9_-_31108285 Show fit	4.52	ENSDART00000003193	gpr183a NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein-coupled receptor 183a
chr25_-_16589461 Show fit	4.52	ENSDART00000064204	cpa4 NCBI UniProt ZFIN ENSEMBL Google Show fit	carboxypeptidase A4
chr24_-_38644937 Show fit	4.48	ENSDART00000170194	slc6a16b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 6, member 16b
chr5_-_8817458 Show fit	4.48	ENSDART00000191098	fgf10b NCBI UniProt ZFIN ENSEMBL Google Show fit	fibroblast growth factor 10b
chr22_-_23591340 Show fit	4.43	ENSDART00000167024	f13b NCBI UniProt ZFIN ENSEMBL Google Show fit	coagulation factor XIII, B polypeptide
chr14_+_30774515 Show fit	4.43	ENSDART00000191666	atl3 NCBI UniProt ZFIN ENSEMBL Google Show fit	atlastin 3
chr17_+_38566717 Show fit	4.43	ENSDART00000145147	sptb NCBI UniProt ZFIN ENSEMBL Google Show fit	spectrin, beta, erythrocytic
chr9_+_29985010 Show fit	4.42	ENSDART00000020743	cmss1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cms1 ribosomal small subunit homolog (yeast)
chr7_-_29164818 Show fit	4.37	ENSDART00000052348	exosc6 NCBI UniProt ZFIN ENSEMBL Google Show fit	exosome component 6
chr10_-_373575 Show fit	4.31	ENSDART00000114487	DMPK NCBI UniProt ZFIN ENSEMBL Google Show fit	DM1 protein kinase
chr11_+_77526 Show fit	4.30	ENSDART00000193521	CABZ01072242.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr5_+_27488975 Show fit	4.29	ENSDART00000123635	sfrp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	secreted frizzled-related protein 1a
chr19_-_24555623 Show fit	4.29	ENSDART00000176022	polr3gla NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) III (DNA directed) polypeptide G like a
chr17_-_45370200 Show fit	4.26	ENSDART00000186208	znf106a NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 106a
chr3_-_34027178 Show fit	4.25	ENSDART00000170201 ENSDART00000151408	ighv1-4 NCBI UniProt ZFIN ENSEMBL Google Show fit ighv14-1 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin heavy variable 1-4 immunoglobulin heavy variable 14-1
chr18_+_38191346 Show fit	4.22	ENSDART00000052703	nucb2b NCBI UniProt ZFIN ENSEMBL Google Show fit	nucleobindin 2b
chr20_+_33875256 Show fit	4.22	ENSDART00000002554	rxrgb NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoid X receptor, gamma b
chr23_+_26017227 Show fit	4.21	ENSDART00000002939	pfkfb1 NCBI UniProt ZFIN ENSEMBL Google Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_37959874 Show fit	4.17	ENSDART00000031719	mpzl2b NCBI UniProt ZFIN ENSEMBL Google Show fit	myelin protein zero-like 2b
chr25_+_16356083 Show fit	4.15	ENSDART00000125925 ENSDART00000125444	tead1a NCBI UniProt ZFIN ENSEMBL Google Show fit	TEA domain family member 1a
chr2_-_30734098 Show fit	4.12	ENSDART00000133769	rp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	retinitis pigmentosa 1 (autosomal dominant)
chr5_-_29534748 Show fit	4.07	ENSDART00000159587	AL831768.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr17_+_24821627 Show fit	4.05	ENSDART00000112389	wdr43 NCBI UniProt ZFIN ENSEMBL Google Show fit	WD repeat domain 43
chr10_+_29850330 Show fit	4.02	ENSDART00000168898	hspa8 NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock protein 8
chr7_+_1505507 Show fit	4.01	ENSDART00000161015	nop10 NCBI UniProt ZFIN ENSEMBL Google Show fit	NOP10 ribonucleoprotein homolog (yeast)
chr9_-_23944470 Show fit	4.00	ENSDART00000138754	col6a3 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type VI, alpha 3
chr1_+_10297027 Show fit	3.99	ENSDART00000152562	eif3f NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 3, subunit F
chr21_+_45685757 Show fit	3.99	ENSDART00000160530	sec24a NCBI UniProt ZFIN ENSEMBL Google Show fit	SEC24 homolog A, COPII coat complex component
chr16_+_33902006 Show fit	3.98	ENSDART00000161807 ENSDART00000159474	gnl2 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein-like 2 (nucleolar)
chr8_+_54135642 Show fit	3.97	ENSDART00000170712	brpf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	bromodomain and PHD finger containing, 1
chr2_+_5793908 Show fit	3.95	ENSDART00000145219	slc35d1b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr25_-_14424406 Show fit	3.95	ENSDART00000073609	prmt7 NCBI UniProt ZFIN ENSEMBL Google Show fit	protein arginine methyltransferase 7
chr16_+_40954481 Show fit	3.95	ENSDART00000058587	gbp NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogen synthase kinase binding protein
chr13_-_24260609 Show fit	3.95	ENSDART00000138747	urb2 NCBI UniProt ZFIN ENSEMBL Google Show fit	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr22_+_21317597 Show fit	3.95	ENSDART00000132605	shc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	SHC (Src homology 2 domain containing) transforming protein 2
chr10_-_57270 Show fit	3.94	ENSDART00000058411	hlcs NCBI UniProt ZFIN ENSEMBL Google Show fit	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr16_-_14074594 Show fit	3.93	ENSDART00000090234	trim109 NCBI UniProt ZFIN ENSEMBL Google Show fit	tripartite motif containing 109
chr5_+_26686639 Show fit	3.92	ENSDART00000079064	tango2 NCBI UniProt ZFIN ENSEMBL Google Show fit	transport and golgi organization 2 homolog (Drosophila)
chr16_-_12787029 Show fit	3.92	ENSDART00000139916	foxj2 NCBI UniProt ZFIN ENSEMBL Google Show fit	forkhead box J2
chr5_+_37744625 Show fit	3.90	ENSDART00000014031	dpf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	D4, zinc and double PHD fingers family 2
chr1_-_26675969 Show fit	3.88	ENSDART00000054184	trmo NCBI UniProt ZFIN ENSEMBL Google Show fit	tRNA methyltransferase O

Network of associatons between targets according to the STRING database.

First level regulatory network of clocka+clockb+npas2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	34.9	GO:0003272	endocardial cushion formation(GO:0003272)
4.9	14.7	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
4.1	16.3	GO:0019401	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
2.9	8.6	GO:0098543	detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
2.8	8.5	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
2.7	18.9	GO:0045901	positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
2.6	10.3	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
2.4	7.1	GO:0042256	mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
1.9	7.6	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.7	8.4	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
1.6	10.9	GO:0048739	cardiac muscle fiber development(GO:0048739)
1.5	13.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
1.5	7.6	GO:0043420	anthranilate metabolic process(GO:0043420)
1.5	15.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
1.5	4.5	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
1.5	4.4	GO:0034475	U4 snRNA 3'-end processing(GO:0034475) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.4	5.7	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
1.4	13.8	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
1.4	1.4	GO:0006107	oxaloacetate metabolic process(GO:0006107)
1.3	7.9	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
1.3	7.8	GO:0048260	positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
1.3	5.0	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
1.2	3.6	GO:1905133	meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
1.1	6.8	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
1.1	6.8	GO:0001678	cellular glucose homeostasis(GO:0001678)
1.1	4.5	GO:0061033	lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.1	6.7	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.0	13.6	GO:0009303	rRNA transcription(GO:0009303)
1.0	9.1	GO:0009435	NAD biosynthetic process(GO:0009435)
1.0	4.0	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.0	5.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
1.0	4.8	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
1.0	9.6	GO:0046037	GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.9	4.6	GO:0030576	nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.9	31.3	GO:0006270	DNA replication initiation(GO:0006270)
0.9	11.7	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.9	8.8	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.9	5.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.9	3.4	GO:0048014	Tie signaling pathway(GO:0048014)
0.9	6.0	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.8	3.4	GO:0089709	L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.8	0.8	GO:0000469	cleavage involved in rRNA processing(GO:0000469)
0.8	4.7	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.7	11.0	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.7	2.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.7	2.1	GO:1990575	mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.7	7.6	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.7	15.3	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.7	22.8	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.7	1.3	GO:0034250	positive regulation of cellular amide metabolic process(GO:0034250)
0.7	3.3	GO:0006031	chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.6	1.9	GO:0060912	cardiac cell fate specification(GO:0060912)
0.6	2.5	GO:0060585	regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.6	1.8	GO:0071312	response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.6	1.8	GO:0006585	dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.6	2.4	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.6	2.4	GO:0051661	maintenance of centrosome location(GO:0051661)
0.6	8.9	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.6	11.8	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6	2.8	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.6	3.3	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.5	12.0	GO:0009749	response to glucose(GO:0009749)
0.5	8.1	GO:0016486	peptide hormone processing(GO:0016486)
0.5	5.4	GO:0070475	rRNA base methylation(GO:0070475)
0.5	4.7	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.5	1.5	GO:0072149	glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.5	2.6	GO:0097066	response to thyroid hormone(GO:0097066)
0.5	8.0	GO:0050728	negative regulation of inflammatory response(GO:0050728)
0.5	3.5	GO:0030908	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.5	6.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.5	12.7	GO:0045454	cell redox homeostasis(GO:0045454)
0.5	1.9	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.5	10.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5	3.7	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.4	2.6	GO:0044209	AMP salvage(GO:0044209)
0.4	2.6	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.4	5.9	GO:0009086	methionine biosynthetic process(GO:0009086)
0.4	33.1	GO:0002181	cytoplasmic translation(GO:0002181)
0.4	23.4	GO:0006414	translational elongation(GO:0006414)
0.4	71.5	GO:0042254	ribosome biogenesis(GO:0042254)
0.4	2.8	GO:0034389	lipid particle organization(GO:0034389)
0.4	7.1	GO:0016203	muscle attachment(GO:0016203)
0.4	1.6	GO:0071962	mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.4	3.7	GO:0055070	copper ion homeostasis(GO:0055070)
0.4	2.9	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.4	1.1	GO:0031590	wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3	1.4	GO:0046168	NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3	1.3	GO:0038093	Fc receptor signaling pathway(GO:0038093)
0.3	3.6	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.3	1.3	GO:0016038	absorption of visible light(GO:0016038)
0.3	2.3	GO:0045109	intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.3	5.9	GO:0060079	excitatory postsynaptic potential(GO:0060079)
0.3	9.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.3	2.5	GO:0044528	regulation of mitochondrial mRNA stability(GO:0044528)
0.3	1.2	GO:2000660	regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3	12.8	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.3	4.2	GO:0032094	response to food(GO:0032094)
0.3	10.6	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.3	1.2	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3	2.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3	4.0	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.3	0.8	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.3	1.1	GO:0030224	monocyte differentiation(GO:0030224)
0.3	4.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.3	8.5	GO:0030488	tRNA methylation(GO:0030488)
0.3	4.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	3.2	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.2	1.5	GO:1902914	negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2	1.0	GO:0051012	microtubule sliding(GO:0051012)
0.2	22.0	GO:0019722	calcium-mediated signaling(GO:0019722)
0.2	1.1	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
0.2	4.6	GO:0007520	myoblast fusion(GO:0007520)
0.2	3.8	GO:0008354	germ cell migration(GO:0008354)
0.2	1.0	GO:0071939	vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.2	1.2	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.2	13.3	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.2	9.0	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.2	0.9	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.2	0.9	GO:0070587	regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2	2.0	GO:0061026	cardiac muscle tissue regeneration(GO:0061026)
0.2	2.7	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.2	8.7	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.2	1.6	GO:1901998	toxin transport(GO:1901998)
0.2	7.2	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.2	1.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.2	0.7	GO:0006526	arginine biosynthetic process(GO:0006526)
0.2	58.9	GO:0006412	translation(GO:0006412) peptide biosynthetic process(GO:0043043)
0.2	1.7	GO:0033700	phospholipid efflux(GO:0033700)
0.2	18.1	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.2	5.9	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.2	4.2	GO:0035329	hippo signaling(GO:0035329)
0.2	2.3	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.2	3.5	GO:0051639	actin filament network formation(GO:0051639)
0.2	0.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	3.1	GO:1901888	regulation of cell junction assembly(GO:1901888)
0.1	6.9	GO:0048821	erythrocyte development(GO:0048821)
0.1	7.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	6.7	GO:0035272	exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.1	1.9	GO:0045762	activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1	4.5	GO:0051014	actin filament severing(GO:0051014)
0.1	2.7	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1	0.4	GO:0051096	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1	0.8	GO:0051454	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1	4.3	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.1	1.4	GO:1900407	regulation of cellular response to oxidative stress(GO:1900407)
0.1	1.5	GO:0008105	asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.1	0.7	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1	2.0	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.8	GO:0070375	ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1	8.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.6	GO:0033986	response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1	2.3	GO:0036294	cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.1	0.4	GO:0019408	dolichol biosynthetic process(GO:0019408)
0.1	1.7	GO:0007035	vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1	0.7	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.8	GO:0032475	otolith formation(GO:0032475)
0.1	4.3	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	2.9	GO:0045104	intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1	4.8	GO:0010842	retina layer formation(GO:0010842)
0.1	2.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.1	3.5	GO:0035987	endodermal cell differentiation(GO:0035987)
0.1	2.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	1.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	1.0	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	10.0	GO:0006457	protein folding(GO:0006457)
0.1	8.7	GO:0006334	nucleosome assembly(GO:0006334)
0.1	1.9	GO:0001757	somite specification(GO:0001757)
0.1	4.2	GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1	8.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.1	2.8	GO:0045332	phospholipid translocation(GO:0045332)
0.1	3.6	GO:0006171	cAMP biosynthetic process(GO:0006171)
0.1	3.7	GO:0007019	microtubule depolymerization(GO:0007019)
0.1	1.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	2.8	GO:0030199	collagen fibril organization(GO:0030199)
0.1	2.0	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.1	14.5	GO:0006954	inflammatory response(GO:0006954)
0.1	3.7	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	4.1	GO:0035082	axoneme assembly(GO:0035082)
0.1	5.3	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	1.2	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.1	0.3	GO:1904105	positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1	0.7	GO:0021754	facial nucleus development(GO:0021754)
0.1	1.8	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	3.2	GO:0000187	activation of MAPK activity(GO:0000187)
0.1	10.5	GO:0045087	innate immune response(GO:0045087)
0.1	2.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	1.6	GO:0007632	visual behavior(GO:0007632)
0.1	0.4	GO:0097250	mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1	3.9	GO:0007030	Golgi organization(GO:0007030)
0.1	1.2	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.1	2.1	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.1	19.4	GO:0046777	protein autophosphorylation(GO:0046777)
0.1	1.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	1.7	GO:0002250	adaptive immune response(GO:0002250)
0.1	0.5	GO:0030317	sperm motility(GO:0030317)
0.1	3.2	GO:0042742	defense response to bacterium(GO:0042742)
0.1	4.0	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	2.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	3.6	GO:0009617	response to bacterium(GO:0009617)
0.1	2.8	GO:0030050	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0	0.4	GO:0050957	equilibrioception(GO:0050957)
0.0	0.4	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	1.0	GO:0031577	mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0	3.1	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	1.1	GO:0014029	neural crest formation(GO:0014029)
0.0	1.7	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.9	GO:0032508	DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0	5.7	GO:0043066	negative regulation of apoptotic process(GO:0043066)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	1.3	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	1.0	GO:0051923	sulfation(GO:0051923)
0.0	1.8	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	3.8	GO:0008284	positive regulation of cell proliferation(GO:0008284)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	1.1	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.5	GO:0019835	cytolysis(GO:0019835)
0.0	1.6	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	1.1	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.0	2.2	GO:0001817	regulation of cytokine production(GO:0001817)
0.0	0.5	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	6.4	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	1.1	GO:0032924	activin receptor signaling pathway(GO:0032924)
0.0	0.2	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0	1.9	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.0	1.3	GO:0042737	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0	0.7	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.0	1.2	GO:0007602	phototransduction(GO:0007602)
0.0	0.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	1.4	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	2.9	GO:0042981	regulation of apoptotic process(GO:0042981)
0.0	0.3	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.3	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.3	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	11.3	GO:0006508	proteolysis(GO:0006508)
0.0	0.4	GO:0036293	response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293) response to oxygen levels(GO:0070482)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	14.7	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
3.5	10.6	GO:0042709	succinate-CoA ligase complex(GO:0042709)
2.9	11.7	GO:0070195	growth hormone receptor complex(GO:0070195)
2.2	34.9	GO:0005869	dynactin complex(GO:0005869)
1.8	22.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.8	8.9	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
1.7	5.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.6	4.8	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
1.4	5.7	GO:0097268	cytoophidium(GO:0097268)
1.2	3.7	GO:0070545	PeBoW complex(GO:0070545)
1.1	4.2	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.0	64.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
1.0	4.0	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.0	4.9	GO:1990923	PET complex(GO:1990923)
0.9	10.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.9	3.7	GO:0061673	mitotic spindle astral microtubule(GO:0061673)
0.9	2.7	GO:0034457	Mpp10 complex(GO:0034457)
0.9	4.4	GO:0008091	spectrin(GO:0008091)
0.9	10.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.8	2.4	GO:0033391	chromatoid body(GO:0033391)
0.8	2.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.7	11.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.7	6.7	GO:0042788	polysomal ribosome(GO:0042788)
0.7	3.3	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.6	4.5	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6	9.4	GO:0030686	90S preribosome(GO:0030686)
0.5	3.2	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.5	8.7	GO:0042555	MCM complex(GO:0042555)
0.4	6.2	GO:0015030	Cajal body(GO:0015030)
0.4	3.3	GO:0030428	cell septum(GO:0030428)
0.4	4.4	GO:0000177	nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.4	7.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.4	5.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.4	1.9	GO:0070724	BMP receptor complex(GO:0070724)
0.4	96.7	GO:0005730	nucleolus(GO:0005730)
0.3	13.7	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.3	20.4	GO:0005643	nuclear pore(GO:0005643)
0.3	3.4	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.3	2.4	GO:0031616	spindle pole centrosome(GO:0031616)
0.3	1.5	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.3	1.5	GO:0071203	WASH complex(GO:0071203)
0.3	1.1	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.3	1.8	GO:0032797	SMN complex(GO:0032797)
0.2	1.0	GO:0008247	1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.2	4.0	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2	1.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	1.8	GO:0097225	sperm midpiece(GO:0097225)
0.2	0.9	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.2	2.9	GO:0014704	intercalated disc(GO:0014704)
0.2	1.8	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	9.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	1.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	2.3	GO:0045095	keratin filament(GO:0045095)
0.2	4.0	GO:0030127	COPII vesicle coat(GO:0030127)
0.2	3.3	GO:0016282	eukaryotic 43S preinitiation complex(GO:0016282)
0.2	1.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	1.0	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2	1.7	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	0.8	GO:0005899	insulin receptor complex(GO:0005899)
0.2	15.2	GO:0030018	Z disc(GO:0030018)
0.2	1.8	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	7.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	2.7	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	5.7	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	17.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	6.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	2.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.7	GO:0032019	mitochondrial cloud(GO:0032019)
0.1	5.0	GO:0032432	actin filament bundle(GO:0032432)
0.1	2.5	GO:0043186	P granule(GO:0043186)
0.1	2.7	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	1.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	9.3	GO:0005581	collagen trimer(GO:0005581)
0.1	1.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	29.3	GO:0015629	actin cytoskeleton(GO:0015629)
0.1	1.0	GO:0048179	activin receptor complex(GO:0048179)
0.1	4.2	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	6.9	GO:0000786	nucleosome(GO:0000786)
0.1	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	0.4	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	1.5	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	6.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	1.3	GO:0043596	nuclear replication fork(GO:0043596)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	0.8	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	1.9	GO:0032156	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	1.8	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.9	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	3.5	GO:0000776	kinetochore(GO:0000776)
0.0	0.2	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0	2.1	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.9	GO:0071565	nBAF complex(GO:0071565)
0.0	1.9	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	1.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	28.6	GO:0005739	mitochondrion(GO:0005739)
0.0	33.1	GO:0005615	extracellular space(GO:0005615)
0.0	1.5	GO:0030173	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0	0.4	GO:0032421	stereocilium bundle(GO:0032421)
0.0	16.3	GO:0005576	extracellular region(GO:0005576)
0.0	0.2	GO:0042613	MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.0	1.6	GO:0005930	axoneme(GO:0005930)
0.0	0.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0044815	DNA packaging complex(GO:0044815)
0.0	6.8	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	15.9	GO:0005829	cytosol(GO:0005829)
0.0	1.3	GO:0005802	trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.6	GO:0004776	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
3.4	13.7	GO:0004373	glycogen (starch) synthase activity(GO:0004373)
2.9	11.7	GO:0004903	growth hormone receptor activity(GO:0004903)
2.9	8.6	GO:0016019	peptidoglycan receptor activity(GO:0016019)
2.8	8.5	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
2.6	10.3	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
2.4	9.7	GO:0033745	L-methionine-(R)-S-oxide reductase activity(GO:0033745)
2.4	7.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
2.3	16.3	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426)
2.2	8.8	GO:0034511	U3 snoRNA binding(GO:0034511)
1.9	7.6	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.8	5.4	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
1.7	6.8	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
1.6	7.8	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.5	9.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
1.4	5.7	GO:0003883	CTP synthase activity(GO:0003883)
1.3	8.0	GO:0032052	bile acid binding(GO:0032052)
1.3	4.0	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.3	7.8	GO:0003938	IMP dehydrogenase activity(GO:0003938)
1.3	8.9	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
1.3	5.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
1.2	7.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.1	6.8	GO:0005536	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.1	10.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
1.0	9.2	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.0	4.0	GO:0005463	UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.9	42.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.8	7.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.8	2.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.8	7.6	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.8	4.5	GO:0008142	oxysterol binding(GO:0008142)
0.7	5.9	GO:0031419	cobalamin binding(GO:0031419)
0.7	13.6	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.7	5.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.6	28.2	GO:0019843	rRNA binding(GO:0019843)
0.6	2.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.6	4.9	GO:0034584	piRNA binding(GO:0034584)
0.6	1.8	GO:0016496	substance P receptor activity(GO:0016496)
0.6	1.8	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.6	11.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.6	1.7	GO:0004422	hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.6	10.7	GO:0070122	isopeptidase activity(GO:0070122)
0.6	11.8	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5	1.1	GO:1901474	drug transmembrane transporter activity(GO:0015238) azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.5	22.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.5	2.6	GO:0004001	adenosine kinase activity(GO:0004001)
0.5	7.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.5	8.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.5	5.9	GO:0051879	Hsp90 protein binding(GO:0051879)
0.5	7.0	GO:0030544	Hsp70 protein binding(GO:0030544)
0.5	2.8	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.4	1.3	GO:0003913	DNA photolyase activity(GO:0003913)
0.4	3.1	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.4	3.5	GO:0005113	patched binding(GO:0005113)
0.4	1.3	GO:0005502	11-cis retinal binding(GO:0005502)
0.4	14.5	GO:0051020	GTPase binding(GO:0051020)
0.4	2.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.4	3.3	GO:0004100	chitin synthase activity(GO:0004100)
0.4	10.9	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.4	2.3	GO:0019215	intermediate filament binding(GO:0019215)
0.4	4.5	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.4	4.5	GO:0030515	snoRNA binding(GO:0030515)
0.4	6.0	GO:0061608	nuclear import signal receptor activity(GO:0061608)
0.4	28.7	GO:0003724	RNA helicase activity(GO:0003724)
0.3	1.4	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3	1.4	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.3	1.7	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3	1.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3	1.8	GO:0004960	thromboxane receptor activity(GO:0004960)
0.3	2.4	GO:0072518	Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3	7.3	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.3	8.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	4.2	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3	2.7	GO:0051920	peroxiredoxin activity(GO:0051920)
0.3	5.9	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.3	48.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	9.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.3	2.9	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.3	4.0	GO:0043994	H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.3	2.0	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.3	3.6	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3	1.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.3	2.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.3	6.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.3	1.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	27.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	2.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.2	0.9	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.2	0.7	GO:0034618	arginine binding(GO:0034618)
0.2	2.6	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.2	2.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	1.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2	1.0	GO:0016531	copper chaperone activity(GO:0016531)
0.2	7.3	GO:0005507	copper ion binding(GO:0005507)
0.2	5.3	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.2	8.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.2	27.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	7.0	GO:0019957	C-C chemokine binding(GO:0019957)
0.2	3.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	1.7	GO:0035198	miRNA binding(GO:0035198)
0.2	1.9	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	0.8	GO:0043560	insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2	1.9	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.7	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	1.0	GO:0016918	retinal binding(GO:0016918) retinol transporter activity(GO:0034632)
0.1	3.6	GO:0004016	adenylate cyclase activity(GO:0004016)
0.1	0.8	GO:0030298	receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1	13.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	6.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	2.5	GO:0051371	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1	1.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	1.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	9.0	GO:0051082	unfolded protein binding(GO:0051082)
0.1	3.7	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	1.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.1	1.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	1.7	GO:0051117	ATPase binding(GO:0051117)
0.1	3.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	2.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	7.6	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	4.7	GO:0017022	myosin binding(GO:0017022)
0.1	1.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	2.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	1.5	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1	0.4	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	1.2	GO:0005165	nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1	13.0	GO:0005179	hormone activity(GO:0005179)
0.1	2.2	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	4.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	3.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	1.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	2.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	3.4	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	1.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.1	5.0	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	2.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0017064	fatty acid amide hydrolase activity(GO:0017064)
0.1	1.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	1.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1	2.2	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.1	2.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	11.0	GO:0042393	histone binding(GO:0042393)
0.1	1.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	2.8	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	15.9	GO:0051015	actin filament binding(GO:0051015)
0.0	0.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	5.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.8	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	1.1	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.6	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	2.2	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	1.4	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	3.8	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	16.1	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	3.1	GO:0043130	ubiquitin binding(GO:0043130)
0.0	7.8	GO:0046982	protein heterodimerization activity(GO:0046982)
0.0	1.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.6	GO:0004382	guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0	2.7	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	1.8	GO:0004601	peroxidase activity(GO:0004601)
0.0	1.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0	0.8	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	1.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	8.3	GO:0008236	serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0	0.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	1.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	1.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	20.0	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	0.4	GO:0035497	cAMP response element binding(GO:0035497)
0.0	1.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.8	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	1.3	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.5	GO:0016878	acid-thiol ligase activity(GO:0016878)
0.0	2.5	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0	1.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	4.7	GO:0003779	actin binding(GO:0003779)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	4.7	GO:0046983	protein dimerization activity(GO:0046983)
0.0	1.9	GO:0000287	magnesium ion binding(GO:0000287)
0.0	4.1	GO:0004672	protein kinase activity(GO:0004672)
0.0	7.7	GO:0005525	GTP binding(GO:0005525)
0.0	1.6	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.5	5.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.4	6.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	8.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.4	6.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.4	11.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	5.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	3.9	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.2	3.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	7.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	3.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	9.5	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	6.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	11.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.2	4.7	PID FOXO PATHWAY	FoxO family signaling
0.2	7.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.2	8.1	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	3.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	10.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	5.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	2.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	1.9	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.8	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	1.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.9	PID ATR PATHWAY	ATR signaling pathway
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	5.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	23.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.4	22.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7	21.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.7	7.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7	7.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.6	71.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.6	6.8	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.6	9.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6	7.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.6	7.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.6	10.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.5	11.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.5	4.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.4	8.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.4	11.4	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.4	8.3	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.3	8.3	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.3	4.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.3	11.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	4.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3	3.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	4.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.3	5.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	2.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	6.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2	2.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	1.3	REACTOME OPSINS	Genes involved in Opsins
0.2	1.9	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.2	2.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	3.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	3.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	1.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	8.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	3.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	11.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	3.7	REACTOME KINESINS	Genes involved in Kinesins
0.2	1.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	2.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	4.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	4.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.8	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.1	4.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	2.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	1.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	3.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	5.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	0.4	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.0	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	2.3	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	2.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	2.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing

Results for clocka+clockb+npas2

Z-value: 1.88

Motif logo

Transcription factors associated with clocka+clockb+npas2

Activity-expression correlation:

Activity profile of clocka+clockb+npas2 motif

Sorted Z-values of clocka+clockb+npas2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of clocka+clockb+npas2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: