ISMARA results: CABZ01090890.1+atf6

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for CABZ01090890.1+atf6

Z-value: 1.35

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Transcription factors associated with CABZ01090890.1+atf6

Gene Symbol	Gene ID	Gene Info
atf6 NCBI UniProt	ENSDARG00000012656	activating transcription factor 6
CABZ01090890.1 NCBI UniProt	ENSDARG00000101369	ENSDARG00000101369

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
atf6	dr11_v1_chr20_-_33864804_33864804	0.83	3.9e-25	Click!

Activity profile of CABZ01090890.1+atf6 motif

Sorted Z-values of CABZ01090890.1+atf6 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_+_33606739 Show fit	11.41	ENSDART00000026464	cfl1l NCBI UniProt Show fit	cofilin 1 (non-muscle), like
chr16_-_45178430 Show fit	8.43	ENSDART00000165186	si:dkey-33i11.9 NCBI UniProt Show fit	si:dkey-33i11.9
chr5_-_9540641 Show fit	7.52	ENSDART00000124384 ENSDART00000160079	gak NCBI UniProt Show fit	cyclin G associated kinase
chr6_+_13506841 Show fit	6.86	ENSDART00000032331	gmppab NCBI UniProt Show fit	GDP-mannose pyrophosphorylase Ab
chr22_+_1796057 Show fit	6.82	ENSDART00000170834	znf1179 NCBI UniProt Show fit	zinc finger protein 1179
chr12_-_17479078 Show fit	6.21	ENSDART00000079115	papss2b NCBI UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr21_+_11105007 Show fit	6.19	ENSDART00000128859 ENSDART00000193105	prlra NCBI UniProt Show fit	prolactin receptor a
chr14_-_11456724 Show fit	5.95	ENSDART00000110424	si:ch211-153b23.4 NCBI UniProt Show fit	si:ch211-153b23.4
chr17_-_22324727 Show fit	5.46	ENSDART00000160341	CU104709.1 NCBI UniProt Show fit
chr18_+_21122818 Show fit	5.39	ENSDART00000060015 ENSDART00000060184	chka NCBI UniProt Show fit	choline kinase alpha

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01090890.1+atf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	19.2	GO:0007030	Golgi organization(GO:0007030)
3.8	11.4	GO:0030043	actin filament fragmentation(GO:0030043)
0.8	8.4	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
1.3	7.5	GO:0072319	clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.0	7.0	GO:0006397	mRNA processing(GO:0006397)
1.1	6.9	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.2	6.6	GO:0030149	sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
2.1	6.2	GO:0034035	sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.5	6.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.6	5.9	GO:0006450	regulation of translational fidelity(GO:0006450)

Showing 1 to 10 of 108 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	32.7	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	15.9	GO:0000139	Golgi membrane(GO:0000139)
0.2	12.0	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.5	9.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	6.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	6.2	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	4.9	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.5	4.7	GO:0089701	U2AF(GO:0089701)
0.0	4.4	GO:0043235	receptor complex(GO:0043235)
0.0	4.2	GO:0005581	collagen trimer(GO:0005581)

Showing 1 to 10 of 47 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	13.9	GO:0051015	actin filament binding(GO:0051015)
0.0	10.6	GO:0005096	GTPase activator activity(GO:0005096)
0.7	8.5	GO:0005537	mannose binding(GO:0005537)
0.0	8.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	7.5	GO:0030276	clathrin binding(GO:0030276)
0.1	7.3	GO:0042803	protein homodimerization activity(GO:0042803)
1.7	6.9	GO:0008905	mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
1.7	6.6	GO:0008117	sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0	6.6	GO:0008289	lipid binding(GO:0008289)
2.1	6.2	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)

Showing 1 to 10 of 85 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.5	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	5.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	4.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	4.0	PID PLK1 PATHWAY	PLK1 signaling events
0.2	3.9	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	3.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	3.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	2.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	2.2	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events

Showing 1 to 10 of 20 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	12.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.2	11.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	5.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	5.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	4.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	4.9	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2	4.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	3.8	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.1	3.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.2	2.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE

Showing 1 to 10 of 21 entries

Results for CABZ01090890.1+atf6

Z-value: 1.35

Motif logo

Transcription factors associated with CABZ01090890.1+atf6

Activity-expression correlation:

Activity profile of CABZ01090890.1+atf6 motif

Sorted Z-values of CABZ01090890.1+atf6 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01090890.1+atf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: