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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF35

Z-value: 0.47

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Transcription factors associated with ZNF35

Gene Symbol Gene ID Gene Info
ZNF35
ENSG00000169981.6 zinc finger protein 35

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF35hg19_v2_chr3_+_44690211_446902670.001.0e+00Click!

Activity profile of ZNF35 motif

Sorted Z-values of ZNF35 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_35553045 0.27 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr4_+_75174180 0.23 ENST00000413830.1
EPGN
epithelial mitogen
chr14_+_76776957 0.23 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr9_+_42671887 0.21 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr12_+_51318513 0.19 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr12_+_25205155 0.18 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr5_-_68339648 0.18 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr21_+_17792672 0.17 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_+_25205446 0.17 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr3_-_171489085 0.16 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr5_-_39203093 0.16 ENST00000515010.1
FYB
FYN binding protein
chr13_-_41240717 0.14 ENST00000379561.5
FOXO1
forkhead box O1
chr4_-_89442940 0.13 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr3_+_29323043 0.13 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr12_+_25205666 0.13 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr17_-_58042075 0.13 ENST00000305783.8
ENST00000589113.1
ENST00000442346.2
RNFT1
ring finger protein, transmembrane 1
chr5_+_139027877 0.13 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr1_+_61869748 0.11 ENST00000357977.5
NFIA
nuclear factor I/A
chr14_-_92198403 0.10 ENST00000553329.1
ENST00000256343.3
CATSPERB
catsper channel auxiliary subunit beta
chrX_-_138724677 0.10 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr1_-_243349684 0.09 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr15_+_96876340 0.09 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_4285923 0.09 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr3_-_148939835 0.09 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr3_-_49967292 0.08 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr6_-_135271219 0.07 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr2_+_177015122 0.07 ENST00000468418.3
HOXD3
homeobox D3
chr5_+_139028510 0.07 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr6_+_32812568 0.07 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr8_-_101157680 0.06 ENST00000428847.2
FBXO43
F-box protein 43
chr8_-_145754428 0.05 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr15_-_76352069 0.05 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr1_-_161008697 0.05 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr21_+_35552978 0.04 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr13_+_109248500 0.04 ENST00000356711.2
MYO16
myosin XVI
chr12_-_22487588 0.04 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr16_+_21623958 0.04 ENST00000568826.1
METTL9
methyltransferase like 9
chr1_-_169599353 0.04 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr6_+_76599809 0.04 ENST00000430435.1
MYO6
myosin VI
chrM_+_4431 0.03 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr3_+_69985734 0.03 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr12_-_22487618 0.03 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr1_-_12677714 0.03 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr7_+_74072288 0.03 ENST00000443166.1
GTF2I
general transcription factor IIi
chr1_+_220701456 0.02 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr4_-_89744365 0.02 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr7_+_80231466 0.02 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr4_+_129730947 0.02 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr10_-_52645416 0.02 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr4_-_99850243 0.02 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr13_-_47471155 0.02 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr7_-_83824449 0.01 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_+_10157276 0.01 ENST00000530758.1
ENST00000256463.6
BRK1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr12_+_4382917 0.01 ENST00000261254.3
CCND2
cyclin D2
chr18_+_39535239 0.01 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr2_+_166150541 0.01 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_-_230787879 0.01 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr3_+_141106458 0.01 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_58571935 0.01 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_116680833 0.01 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr7_+_123488124 0.00 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr13_-_36429763 0.00 ENST00000379893.1
DCLK1
doublecortin-like kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF35

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)