Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for YY1_YY2
Z-value: 1.13
Motif logo
Transcription factors associated with YY1_YY2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| YY2 | hg19_v2_chrX_+_21874105_21874105 | 0.72 | 1.1e-01 | Click! |
| YY1 | hg19_v2_chr14_+_100705322_100705360 | -0.44 | 3.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of YY1_YY2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.2 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.0 | 1.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 1.4 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 1.4 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.0 | 1.3 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.2 | 1.2 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.0 | 1.1 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.9 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.1 | 0.8 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.8 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 1.9 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 1.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 1.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 1.0 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.0 | 1.0 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.2 | 0.8 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.0 | 0.8 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 0.6 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | GO:0043996 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.0 | 1.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 1.5 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.0 | 1.2 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.3 | 1.0 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.0 | 1.0 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.9 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.2 | 0.8 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 0.8 | GO:0004707 | MAP kinase activity(GO:0004707) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.7 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.6 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.2 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.1 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 2.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 1.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 1.0 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 0.8 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.8 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.7 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.7 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |