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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for VSX1

Z-value: 1.16

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Transcription factors associated with VSX1

Gene Symbol Gene ID Gene Info
VSX1
ENSG00000100987.10 visual system homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VSX1hg19_v2_chr20_-_25062767_25062779-0.276.1e-01Click!

Activity profile of VSX1 motif

Sorted Z-values of VSX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_47655686 1.48 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr19_+_36239576 1.09 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr5_-_147286065 0.89 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr6_+_43968306 0.89 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr17_+_67590125 0.82 ENST00000591334.1
AC003051.1
AC003051.1
chr13_-_30160925 0.81 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_+_46970134 0.55 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_+_152943122 0.46 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr6_-_30685214 0.46 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr10_-_99205607 0.44 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr1_-_152386732 0.44 ENST00000271835.3
CRNN
cornulin
chr17_-_76732928 0.44 ENST00000589768.1
CYTH1
cytohesin 1
chr4_-_74853897 0.43 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr8_-_131399110 0.42 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr19_-_49622348 0.41 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr6_+_27861190 0.40 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr6_-_30684898 0.40 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr19_+_56652643 0.39 ENST00000586123.1
ZNF444
zinc finger protein 444
chr19_-_6737576 0.39 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr5_-_13944652 0.38 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr2_-_70520832 0.38 ENST00000454893.1
ENST00000272348.2
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr20_+_60813535 0.37 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
OSBPL2
oxysterol binding protein-like 2
chr2_+_149974684 0.36 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr2_-_191878874 0.36 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_240322643 0.36 ENST00000345617.3
HDAC4
histone deacetylase 4
chr7_+_99699280 0.35 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr14_-_24711865 0.35 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr15_-_43559055 0.35 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr3_+_47324424 0.35 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr6_-_31782813 0.34 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr12_-_56693758 0.34 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr19_+_50180409 0.34 ENST00000391851.4
PRMT1
protein arginine methyltransferase 1
chr17_-_47841485 0.34 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr6_+_26199737 0.34 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr14_-_24711470 0.33 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr9_+_140135665 0.33 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr20_-_17662705 0.33 ENST00000455029.2
RRBP1
ribosome binding protein 1
chr19_-_15529790 0.32 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
AKAP8L
A kinase (PRKA) anchor protein 8-like
chr2_-_240322685 0.32 ENST00000544989.1
HDAC4
histone deacetylase 4
chr14_-_24711764 0.32 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_-_54618650 0.32 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr15_-_41522889 0.30 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr7_+_100136811 0.30 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr1_-_36916011 0.30 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr1_+_43148059 0.30 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr17_+_46970127 0.29 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr2_-_25451065 0.29 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr14_-_24711806 0.28 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_154947126 0.28 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr1_-_45956868 0.28 ENST00000451835.2
TESK2
testis-specific kinase 2
chr19_+_45394477 0.28 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_+_50180507 0.28 ENST00000454376.2
ENST00000524771.1
PRMT1
protein arginine methyltransferase 1
chr12_-_56694083 0.28 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS
citrate synthase
chr4_+_175204865 0.28 ENST00000505124.1
CEP44
centrosomal protein 44kDa
chr3_+_186288454 0.28 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr19_+_50180317 0.27 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr1_-_154946825 0.27 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr12_+_110011571 0.27 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr19_-_54663473 0.27 ENST00000222224.3
LENG1
leukocyte receptor cluster (LRC) member 1
chr2_+_135596106 0.26 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chrM_+_10758 0.26 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr6_+_30687978 0.26 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr16_-_89883015 0.26 ENST00000563673.1
ENST00000389301.3
ENST00000568369.1
ENST00000534992.1
ENST00000389302.3
ENST00000543736.1
FANCA
Fanconi anemia, complementation group A
chr19_-_54619006 0.26 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr17_+_5323492 0.25 ENST00000405578.4
ENST00000574003.1
RPAIN
RPA interacting protein
chr6_-_32145861 0.25 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr1_+_154947148 0.25 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr11_-_76155618 0.25 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr16_-_30773372 0.25 ENST00000545825.1
ENST00000541260.1
C16orf93
chromosome 16 open reading frame 93
chr8_-_145159083 0.24 ENST00000398712.2
SHARPIN
SHANK-associated RH domain interactor
chr3_-_47324008 0.24 ENST00000425853.1
KIF9
kinesin family member 9
chr8_-_29120604 0.24 ENST00000521515.1
KIF13B
kinesin family member 13B
chr11_+_12308447 0.24 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr19_+_19303720 0.24 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr5_+_177631497 0.23 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr2_-_70780770 0.23 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chrX_-_24665353 0.23 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr19_-_19302931 0.23 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr19_+_13001840 0.23 ENST00000222214.5
ENST00000589039.1
ENST00000591470.1
ENST00000457854.1
ENST00000422947.2
ENST00000588905.1
ENST00000587072.1
GCDH
glutaryl-CoA dehydrogenase
chr7_+_99699179 0.22 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr5_+_151151471 0.22 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_-_6052463 0.22 ENST00000378156.4
NPHP4
nephronophthisis 4
chr10_-_1095050 0.22 ENST00000381344.3
IDI1
isopentenyl-diphosphate delta isomerase 1
chrX_+_70503037 0.21 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr16_+_84225029 0.21 ENST00000567685.1
ADAD2
adenosine deaminase domain containing 2
chr5_+_177631523 0.21 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr11_+_67798090 0.20 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr19_+_54641444 0.20 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr11_-_4629367 0.20 ENST00000533021.1
TRIM68
tripartite motif containing 68
chr5_-_176738883 0.20 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr19_+_10828724 0.20 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr19_-_6737241 0.20 ENST00000430424.4
ENST00000597298.1
GPR108
G protein-coupled receptor 108
chr4_+_153021899 0.19 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1
RP11-18H21.1
chr22_+_39916558 0.19 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr5_-_137374288 0.19 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr17_-_57229155 0.19 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr14_-_73925225 0.19 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr9_+_131799213 0.19 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
FAM73B
family with sequence similarity 73, member B
chr21_-_42219065 0.19 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr17_+_46970178 0.19 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr18_-_61329118 0.18 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_-_154946792 0.18 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_-_34931458 0.18 ENST00000298130.4
SPTSSA
serine palmitoyltransferase, small subunit A
chr20_-_32274179 0.18 ENST00000343380.5
E2F1
E2F transcription factor 1
chr9_+_104296163 0.18 ENST00000374819.2
ENST00000479306.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr10_-_104001231 0.18 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr1_+_70876891 0.18 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr19_+_45973120 0.18 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr19_-_39881669 0.17 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_-_33913708 0.17 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_10828795 0.17 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
DNM2
dynamin 2
chr19_+_4007644 0.17 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr14_-_74959994 0.17 ENST00000238633.2
ENST00000434013.2
NPC2
Niemann-Pick disease, type C2
chrX_-_153363125 0.17 ENST00000407218.1
ENST00000453960.2
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr9_+_34646651 0.17 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chrX_+_151999511 0.17 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr11_-_122932730 0.17 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr11_-_122933043 0.17 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr20_-_17662878 0.17 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1
ribosome binding protein 1
chr17_-_74722672 0.17 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr14_+_29236269 0.17 ENST00000313071.4
FOXG1
forkhead box G1
chr19_+_46498704 0.16 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr1_+_151138526 0.16 ENST00000368902.1
SCNM1
sodium channel modifier 1
chr6_-_85474219 0.16 ENST00000369663.5
TBX18
T-box 18
chr15_+_73735490 0.16 ENST00000331090.6
ENST00000560581.1
C15orf60
chromosome 15 open reading frame 60
chr19_-_14247365 0.16 ENST00000592798.1
ENST00000474890.1
ASF1B
anti-silencing function 1B histone chaperone
chr16_-_67965756 0.16 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr18_-_59415987 0.16 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
RP11-879F14.1
chr21_-_34914394 0.16 ENST00000361093.5
ENST00000381815.4
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr1_+_44115814 0.16 ENST00000372396.3
KDM4A
lysine (K)-specific demethylase 4A
chr8_+_145159415 0.16 ENST00000534585.1
MAF1
MAF1 homolog (S. cerevisiae)
chr17_-_42277203 0.16 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr4_-_89205350 0.16 ENST00000509340.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr7_-_99716940 0.16 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chrX_+_107334983 0.16 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr4_-_82393009 0.16 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr5_+_151151504 0.15 ENST00000356245.3
ENST00000507878.2
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chrX_+_19373700 0.15 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chrX_+_133930798 0.15 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chrX_+_70503433 0.15 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO
non-POU domain containing, octamer-binding
chr18_-_45457192 0.15 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr14_-_71276211 0.15 ENST00000381250.4
ENST00000555993.2
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr5_+_148737562 0.15 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr8_+_145159376 0.15 ENST00000322428.5
MAF1
MAF1 homolog (S. cerevisiae)
chr7_-_72971934 0.15 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr9_+_34646624 0.15 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_+_160211481 0.15 ENST00000367034.4
MRPL18
mitochondrial ribosomal protein L18
chr12_-_6961050 0.15 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr20_+_36322408 0.15 ENST00000361383.6
ENST00000447935.1
ENST00000405275.2
CTNNBL1
catenin, beta like 1
chr20_+_18488137 0.14 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr15_+_41523417 0.14 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr6_-_62996066 0.14 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr12_-_57039739 0.14 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_-_44613494 0.14 ENST00000431640.1
ENST00000258772.5
DDX56
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr14_-_104181771 0.14 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr7_-_99699538 0.14 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr17_-_4871085 0.14 ENST00000575142.1
ENST00000206020.3
SPAG7
sperm associated antigen 7
chr6_-_49755019 0.14 ENST00000304801.3
PGK2
phosphoglycerate kinase 2
chr11_+_119205222 0.13 ENST00000311413.4
RNF26
ring finger protein 26
chr15_+_90118723 0.13 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr11_-_66056478 0.13 ENST00000431556.2
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chrX_+_85403445 0.13 ENST00000373131.1
DACH2
dachshund homolog 2 (Drosophila)
chr14_-_24584138 0.13 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr17_-_47785504 0.13 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
SLC35B1
solute carrier family 35, member B1
chr11_+_63754294 0.13 ENST00000543988.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr1_-_11322551 0.13 ENST00000361445.4
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr19_+_17420340 0.13 ENST00000359866.4
DDA1
DET1 and DDB1 associated 1
chr19_-_15236173 0.13 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr16_+_69345243 0.13 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr4_-_186570679 0.13 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr14_+_104182061 0.13 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr3_+_118905564 0.13 ENST00000460625.1
UPK1B
uroplakin 1B
chr8_-_29120580 0.13 ENST00000524189.1
KIF13B
kinesin family member 13B
chr6_-_26032288 0.13 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr20_+_56136136 0.13 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr14_+_24584056 0.13 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr12_-_56694142 0.12 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS
citrate synthase
chr17_-_74722536 0.12 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr3_-_47324242 0.12 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9
kinesin family member 9
chr3_+_138340049 0.12 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr11_+_67798114 0.12 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr17_-_46799872 0.12 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr7_-_111424462 0.12 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr5_-_150138246 0.12 ENST00000518015.1
DCTN4
dynactin 4 (p62)
chr15_+_90118685 0.12 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr4_-_119759795 0.12 ENST00000419654.2
SEC24D
SEC24 family member D
chr19_-_39421377 0.12 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
SARS2
seryl-tRNA synthetase 2, mitochondrial
chr14_+_104182105 0.12 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr11_+_63753883 0.12 ENST00000538426.1
ENST00000543004.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr19_-_13227514 0.12 ENST00000587487.1
ENST00000592814.1
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr12_+_3000073 0.12 ENST00000397132.2
TULP3
tubby like protein 3
chr1_+_100817262 0.12 ENST00000455467.1
CDC14A
cell division cycle 14A
chr17_+_1733251 0.12 ENST00000570451.1
RPA1
replication protein A1, 70kDa
chr14_+_100070869 0.12 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr4_-_105416039 0.12 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr6_+_42018614 0.12 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr4_-_138453606 0.12 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr6_+_33422343 0.12 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chrM_+_4431 0.12 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr19_+_7694623 0.11 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.9 GO:0046985 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.4 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.8 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:1903525 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.2 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490) dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.1 0.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:1903774 late endosomal microautophagy(GO:0061738) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:1903862 flavin adenine dinucleotide metabolic process(GO:0072387) positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0006568 tryptophan metabolic process(GO:0006568)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.7 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.0 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.2 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.2 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.3 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 0.9 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.2 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.2 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 1.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs