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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for UUGGCAA
Z-value: 0.84
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miRNA associated with seed UUGGCAA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-182-5p
|
MIMAT0000259 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_94964354 Show fit | 0.45 |
ENST00000536441.1
|
sestrin 3 |
|
| chr12_-_104234966 Show fit | 0.39 |
ENST00000392876.3
|
5'-nucleotidase domain containing 3 |
|
| chr5_-_74326724 Show fit | 0.37 |
ENST00000322348.4
|
glucosaminyl (N-acetyl) transferase 4, core 2 |
|
| chr2_-_102003987 Show fit | 0.37 |
ENST00000324768.5
|
cellular repressor of E1A-stimulated genes 2 |
|
| chr9_+_19408999 Show fit | 0.33 |
ENST00000340967.2
|
alkaline ceramidase 2 |
|
| chr21_-_34852304 Show fit | 0.33 |
ENST00000542230.2
|
transmembrane protein 50B |
|
| chr3_-_182698381 Show fit | 0.33 |
ENST00000292782.4
|
DCN1, defective in cullin neddylation 1, domain containing 1 |
|
| chr10_+_111767720 Show fit | 0.32 |
ENST00000356080.4
ENST00000277900.8 |
adducin 3 (gamma) |
|
| chr2_+_46769798 Show fit | 0.31 |
ENST00000238738.4
|
ras homolog family member Q |
|
| chr8_-_124665190 Show fit | 0.30 |
ENST00000325995.7
|
kelch-like family member 38 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGCAA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0002118 | aggressive behavior(GO:0002118) |
| 0.0 | 0.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 0.4 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.3 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
| 0.1 | 0.3 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.0 | 0.3 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 0.3 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.3 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.0 | 0.3 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.0 | 0.3 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.4 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.2 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.0 | 0.2 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.1 | GO:0043291 | RAVE complex(GO:0043291) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.0 | 0.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 0.3 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.1 | 0.3 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 0.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.3 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 0.3 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 0.2 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.1 | 0.2 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.0 | 0.2 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.1 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.4 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.3 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.2 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.2 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.0 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |