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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP63

Z-value: 1.04

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
TP63
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189507523_1895075900.394.4e-01Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_3189861 0.84 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chrX_+_9880412 0.57 ENST00000418909.2
SHROOM2
shroom family member 2
chr11_+_393428 0.55 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr16_+_57653596 0.51 ENST00000568791.1
ENST00000570044.1
GPR56
G protein-coupled receptor 56
chr1_+_17575584 0.44 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr16_+_57653625 0.42 ENST00000567553.1
ENST00000565314.1
GPR56
G protein-coupled receptor 56
chr6_-_33663474 0.40 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr9_-_88874519 0.40 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr7_+_79763271 0.38 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr16_+_57653989 0.38 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr19_-_4717835 0.37 ENST00000599248.1
DPP9
dipeptidyl-peptidase 9
chr16_+_1832902 0.37 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr5_-_42811986 0.36 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr7_+_80267973 0.35 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr9_+_35906176 0.35 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chrX_+_9880590 0.34 ENST00000452575.1
SHROOM2
shroom family member 2
chr1_-_117753540 0.34 ENST00000328189.3
ENST00000369458.3
VTCN1
V-set domain containing T cell activation inhibitor 1
chr2_+_217524323 0.34 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr15_+_40532723 0.33 ENST00000558878.1
ENST00000558183.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chrX_-_138724677 0.32 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr17_+_1646130 0.32 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_+_67197288 0.31 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr17_+_78397320 0.31 ENST00000521634.1
ENST00000572886.1
ENDOV
endonuclease V
chr1_-_19229218 0.31 ENST00000432718.1
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr16_+_57653854 0.31 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr16_-_75467274 0.30 ENST00000566254.1
CFDP1
craniofacial development protein 1
chr1_-_1356719 0.30 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr19_-_10420459 0.29 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr1_+_86889769 0.29 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr11_+_27062272 0.29 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_72439997 0.29 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr19_-_3500635 0.29 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr4_+_105828492 0.29 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr15_-_42448788 0.28 ENST00000382396.4
ENST00000397272.3
PLA2G4F
phospholipase A2, group IVF
chr16_-_30006922 0.27 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr7_-_110174754 0.26 ENST00000435466.1
AC003088.1
AC003088.1
chr19_+_507299 0.26 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr6_-_109330702 0.26 ENST00000356644.7
SESN1
sestrin 1
chr22_+_50628999 0.25 ENST00000395827.1
TRABD
TraB domain containing
chr1_-_1356628 0.25 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr5_-_42812143 0.25 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr8_+_22960426 0.25 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr11_-_77899634 0.24 ENST00000526208.1
ENST00000529350.1
ENST00000530018.1
ENST00000528776.1
KCTD21
potassium channel tetramerization domain containing 21
chr11_-_111782484 0.24 ENST00000533971.1
CRYAB
crystallin, alpha B
chr11_-_111782696 0.24 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr1_-_38412683 0.23 ENST00000373024.3
ENST00000373023.2
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr7_-_72742085 0.23 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr9_-_119449483 0.23 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
ASTN2
astrotactin 2
chr11_+_1856034 0.23 ENST00000341958.3
SYT8
synaptotagmin VIII
chr14_+_35514323 0.23 ENST00000555211.1
FAM177A1
family with sequence similarity 177, member A1
chrX_-_111923145 0.23 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr4_+_671711 0.22 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr2_+_198365122 0.22 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr15_+_69365272 0.22 ENST00000559914.1
ENST00000558369.1
LINC00277
long intergenic non-protein coding RNA 277
chr1_+_3607228 0.21 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73
tumor protein p73
chr11_+_832804 0.21 ENST00000397420.3
ENST00000525718.1
CD151
CD151 molecule (Raph blood group)
chr4_+_105828537 0.21 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr12_-_122712038 0.21 ENST00000413918.1
ENST00000443649.3
DIABLO
diablo, IAP-binding mitochondrial protein
chr1_-_19229014 0.21 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr15_-_72767490 0.21 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr16_-_70729496 0.20 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr3_-_49395892 0.20 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr15_+_42697065 0.20 ENST00000565559.1
CAPN3
calpain 3, (p94)
chr8_+_117778736 0.20 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr17_+_38337491 0.20 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr6_+_31691121 0.20 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
C6orf25
chromosome 6 open reading frame 25
chr1_+_223354486 0.19 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr2_+_208104497 0.19 ENST00000430494.1
AC007879.7
AC007879.7
chr7_-_100287071 0.19 ENST00000275732.5
GIGYF1
GRB10 interacting GYF protein 1
chr1_+_38158090 0.19 ENST00000373055.1
ENST00000327331.2
CDCA8
cell division cycle associated 8
chrX_-_129244336 0.19 ENST00000434609.1
ELF4
E74-like factor 4 (ets domain transcription factor)
chr3_-_33700589 0.19 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr11_+_76493294 0.19 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr1_-_19229248 0.19 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr11_+_18433840 0.18 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr22_-_38577782 0.18 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr2_+_169312725 0.18 ENST00000392687.4
CERS6
ceramide synthase 6
chr19_-_11688260 0.18 ENST00000590832.1
ACP5
acid phosphatase 5, tartrate resistant
chr20_-_34542548 0.18 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr4_-_40516560 0.18 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr5_-_180235755 0.18 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_-_19887185 0.17 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663
long intergenic non-protein coding RNA 663
chr20_+_57264187 0.17 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr19_+_15783879 0.17 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr19_-_51504411 0.17 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr3_-_49395705 0.17 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr17_-_18430160 0.17 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr2_+_169312350 0.17 ENST00000305747.6
CERS6
ceramide synthase 6
chr19_+_42364313 0.16 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr16_+_53483983 0.16 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr11_-_104972158 0.16 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr6_-_10747802 0.16 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr11_-_71814422 0.16 ENST00000278671.5
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr8_-_37351344 0.16 ENST00000520422.1
RP11-150O12.1
RP11-150O12.1
chr1_-_118727781 0.16 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr17_-_4938712 0.16 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr6_+_127898312 0.16 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr11_+_61583968 0.15 ENST00000517839.1
FADS2
fatty acid desaturase 2
chr14_-_100046444 0.15 ENST00000554996.1
CCDC85C
coiled-coil domain containing 85C
chr19_+_41094612 0.15 ENST00000595726.1
SHKBP1
SH3KBP1 binding protein 1
chr19_+_18496957 0.15 ENST00000252809.3
GDF15
growth differentiation factor 15
chr11_-_71814276 0.15 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr10_-_90751038 0.15 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr4_+_95916947 0.15 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr8_+_145218673 0.15 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chrX_-_138724994 0.15 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr18_-_19283649 0.15 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr1_+_24646263 0.15 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chrX_-_153602991 0.15 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr12_-_55042140 0.14 ENST00000293371.6
ENST00000456047.2
DCD
dermcidin
chr5_+_162864575 0.14 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr15_-_89456630 0.14 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr11_+_65686728 0.14 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr12_-_10321754 0.14 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr19_+_42364460 0.14 ENST00000593863.1
RPS19
ribosomal protein S19
chrX_+_153029633 0.14 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3
plexin B3
chrX_+_2670153 0.14 ENST00000509484.2
XG
Xg blood group
chr10_-_88729200 0.14 ENST00000474994.2
MMRN2
multimerin 2
chr1_+_85527987 0.13 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr19_+_46498704 0.13 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr15_-_89456593 0.13 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chr6_-_33385902 0.13 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr16_+_30006997 0.13 ENST00000304516.7
INO80E
INO80 complex subunit E
chr16_+_30007524 0.13 ENST00000567254.1
ENST00000567705.1
INO80E
INO80 complex subunit E
chr4_+_95917383 0.13 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr19_-_47231216 0.13 ENST00000594287.2
STRN4
striatin, calmodulin binding protein 4
chr2_-_176033066 0.13 ENST00000437522.1
ATF2
activating transcription factor 2
chr4_+_3388057 0.13 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr8_+_22437664 0.13 ENST00000436754.1
ENST00000426493.1
ENST00000429812.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr9_+_71944241 0.13 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr1_-_26197744 0.12 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr4_-_10023095 0.12 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chrX_-_153583257 0.12 ENST00000438732.1
FLNA
filamin A, alpha
chr4_-_129209221 0.12 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr6_+_35265586 0.12 ENST00000542066.1
ENST00000316637.5
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr22_+_40573921 0.12 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr17_-_34079897 0.12 ENST00000254466.6
ENST00000587565.1
GAS2L2
growth arrest-specific 2 like 2
chr18_-_28742813 0.12 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr13_-_96296944 0.12 ENST00000361396.2
ENST00000376829.2
DZIP1
DAZ interacting zinc finger protein 1
chr12_-_15942503 0.12 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr10_-_105212141 0.12 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr18_+_57567180 0.12 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr20_-_52790512 0.12 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr22_-_50946113 0.12 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
LMF2
lipase maturation factor 2
chr1_+_24645865 0.12 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr8_+_67025516 0.11 ENST00000517961.2
AC084082.3
AC084082.3
chr19_-_5293243 0.11 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr11_-_93271058 0.11 ENST00000527149.1
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr5_-_64920115 0.11 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr1_+_24645807 0.11 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr10_-_105212059 0.11 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr3_+_69915363 0.11 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr2_-_27603582 0.11 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr3_+_152552685 0.11 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr15_-_90233866 0.11 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr22_-_38577731 0.11 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr1_+_203256898 0.11 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr1_+_97187318 0.11 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr16_+_30006615 0.11 ENST00000563197.1
INO80E
INO80 complex subunit E
chr17_-_39459103 0.11 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr22_+_24999114 0.11 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr6_-_111804905 0.11 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr19_-_12662240 0.11 ENST00000416136.1
ENST00000428311.1
ZNF564
ZNF709
zinc finger protein 564
ZNF709
chr1_+_24646002 0.11 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_148663729 0.10 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr8_+_22437965 0.10 ENST00000409141.1
ENST00000265810.4
PDLIM2
PDZ and LIM domain 2 (mystique)
chr1_+_17906970 0.10 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_+_3186521 0.10 ENST00000537971.1
ENST00000011898.5
TSPAN9
tetraspanin 9
chr8_-_18942240 0.10 ENST00000521475.1
PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_24645915 0.10 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr22_+_39378346 0.10 ENST00000407298.3
APOBEC3B
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr19_-_11639931 0.10 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr3_+_23986748 0.10 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr11_+_67776012 0.10 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr8_-_67341208 0.10 ENST00000499642.1
RP11-346I3.4
RP11-346I3.4
chr19_-_11688500 0.10 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr13_+_42846272 0.10 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr15_+_40532058 0.10 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_-_94417562 0.09 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr10_+_93558069 0.09 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr14_-_94595993 0.09 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr11_-_68611721 0.09 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr11_-_64889649 0.09 ENST00000434372.2
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_-_23021533 0.09 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr11_-_72432950 0.09 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_88974236 0.09 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr5_+_115420688 0.09 ENST00000274458.4
COMMD10
COMM domain containing 10
chr5_+_174905532 0.09 ENST00000502393.1
ENST00000506963.1
SFXN1
sideroflexin 1
chr7_+_48211048 0.09 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr6_+_80129989 0.09 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr7_+_140396756 0.09 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chrX_-_45710920 0.09 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr2_+_112813134 0.08 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr15_+_41136263 0.08 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr19_-_46288917 0.08 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr17_+_79859985 0.08 ENST00000333383.7
NPB
neuropeptide B
chr1_-_46089718 0.08 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17
coiled-coil domain containing 17
chr2_+_178257372 0.08 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr20_-_43743790 0.08 ENST00000307971.4
ENST00000372789.4
WFDC5
WAP four-disulfide core domain 5
chr17_+_20483037 0.08 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 0.7 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 0.3 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.4 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.2 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.4 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.0 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.3 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.4 GO:0097413 Lewy body(GO:0097413)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway