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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP53

Z-value: 0.70

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_75908560.661.6e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_26859300 0.61 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr18_+_44497455 0.42 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr2_+_197504278 0.42 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr4_+_186347388 0.36 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr1_-_54483803 0.31 ENST00000371360.1
ENST00000545928.1
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr22_-_24093267 0.29 ENST00000341976.3
ZNF70
zinc finger protein 70
chr11_+_65222698 0.28 ENST00000309775.7
AP000769.1
Uncharacterized protein
chr4_+_6784358 0.26 ENST00000508423.1
KIAA0232
KIAA0232
chr3_+_32148106 0.25 ENST00000425459.1
ENST00000431009.1
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr1_+_54519242 0.23 ENST00000234827.1
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr22_+_29168652 0.23 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr6_-_109804412 0.23 ENST00000230122.3
ZBTB24
zinc finger and BTB domain containing 24
chrX_+_3189861 0.23 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr1_-_54483842 0.22 ENST00000371362.3
ENST00000420619.1
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr19_+_28284803 0.21 ENST00000586220.1
ENST00000588784.1
ENST00000591549.1
ENST00000585827.1
ENST00000588636.1
ENST00000587188.1
CTC-459F4.3
CTC-459F4.3
chr5_+_6766004 0.21 ENST00000506093.1
RP11-332J15.3
RP11-332J15.3
chr15_+_100347228 0.21 ENST00000559714.1
ENST00000560059.1
CTD-2054N24.2
Uncharacterized protein
chr2_+_11295624 0.21 ENST00000402361.1
ENST00000428481.1
PQLC3
PQ loop repeat containing 3
chr19_-_14048804 0.21 ENST00000254320.3
ENST00000586075.1
PODNL1
podocan-like 1
chr7_-_100239132 0.21 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr7_-_21985489 0.20 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr5_-_138775177 0.20 ENST00000302060.5
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr12_+_56546363 0.20 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr3_+_49977440 0.20 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RBM6
RNA binding motif protein 6
chr12_-_126467906 0.20 ENST00000507313.1
ENST00000545784.1
LINC00939
long intergenic non-protein coding RNA 939
chr4_-_87374330 0.18 ENST00000511328.1
ENST00000503911.1
MAPK10
mitogen-activated protein kinase 10
chr16_-_14788526 0.18 ENST00000438167.3
PLA2G10
phospholipase A2, group X
chrX_-_106959631 0.18 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr19_-_6591113 0.17 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr17_+_78234625 0.17 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr3_+_49977490 0.17 ENST00000539992.1
RBM6
RNA binding motif protein 6
chr19_-_38714847 0.17 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr11_-_68611721 0.16 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr10_-_105212141 0.16 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr7_+_72742178 0.16 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr7_+_63361201 0.16 ENST00000450544.1
RP11-340I6.8
RP11-340I6.8
chr3_+_49977523 0.15 ENST00000422955.1
RBM6
RNA binding motif protein 6
chrX_-_48827976 0.15 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr5_-_64920115 0.15 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr16_+_77756399 0.15 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_-_49533521 0.15 ENST00000523038.1
RP11-567J20.1
RP11-567J20.1
chr16_-_15149828 0.15 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr8_-_12293852 0.15 ENST00000262365.4
ENST00000351291.4
ENST00000309608.5
ENST00000527331.1
ENST00000532480.1
ENST00000393715.3
FAM86B2
family with sequence similarity 86, member B2
chr6_+_139135648 0.14 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr19_+_57874835 0.14 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr4_+_6784401 0.13 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr16_-_15149917 0.13 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr19_+_51293672 0.13 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chr4_-_129209221 0.13 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr2_+_198365095 0.13 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr4_+_103422499 0.13 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_204494618 0.12 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr1_+_2477831 0.12 ENST00000606645.1
RP3-395M20.12
RP3-395M20.12
chr10_+_96305535 0.12 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr5_-_168006324 0.12 ENST00000522176.1
PANK3
pantothenate kinase 3
chr5_-_72861175 0.12 ENST00000504641.1
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr1_-_169396666 0.12 ENST00000456107.1
ENST00000367805.3
CCDC181
coiled-coil domain containing 181
chr11_-_47546250 0.12 ENST00000543178.1
CELF1
CUGBP, Elav-like family member 1
chr13_+_38923959 0.12 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr18_-_28622699 0.11 ENST00000360428.4
DSC3
desmocollin 3
chr15_+_79165296 0.11 ENST00000558746.1
ENST00000558830.1
ENST00000559345.1
MORF4L1
mortality factor 4 like 1
chr22_+_29279552 0.11 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr8_-_29592736 0.11 ENST00000518623.1
LINC00589
long intergenic non-protein coding RNA 589
chr15_+_79165372 0.11 ENST00000558502.1
MORF4L1
mortality factor 4 like 1
chr18_-_28622774 0.11 ENST00000434452.1
DSC3
desmocollin 3
chr11_-_77122928 0.11 ENST00000528203.1
ENST00000528592.1
ENST00000528633.1
ENST00000529248.1
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr10_-_105212059 0.11 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr7_+_72742162 0.11 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr15_+_79165151 0.10 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr2_+_208104497 0.10 ENST00000430494.1
AC007879.7
AC007879.7
chr10_+_90750493 0.10 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr14_+_36295638 0.10 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr5_+_72861560 0.10 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr1_-_114447620 0.10 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr7_-_100493744 0.10 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr1_+_211432700 0.10 ENST00000452621.2
RCOR3
REST corepressor 3
chr7_-_74221288 0.10 ENST00000451013.2
GTF2IRD2
GTF2I repeat domain containing 2
chr15_+_79165222 0.10 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr19_-_28284793 0.10 ENST00000590523.1
LINC00662
long intergenic non-protein coding RNA 662
chr4_+_153457404 0.09 ENST00000604157.1
ENST00000594836.1
MIR4453
microRNA 4453
chr6_-_114292284 0.09 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
HDAC2
histone deacetylase 2
chr5_+_178487354 0.09 ENST00000315475.6
ZNF354C
zinc finger protein 354C
chr22_-_28392227 0.09 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr15_-_63448973 0.09 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr14_-_64971288 0.09 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr19_+_42746927 0.09 ENST00000378108.1
AC006486.1
AC006486.1
chr9_-_116037840 0.09 ENST00000374206.3
CDC26
cell division cycle 26
chr3_+_183894737 0.09 ENST00000432591.1
ENST00000431779.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr15_+_79165112 0.09 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr12_+_44229846 0.09 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr2_-_18741882 0.09 ENST00000381249.3
RDH14
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr7_+_116165754 0.09 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr11_+_5712234 0.09 ENST00000414641.1
TRIM22
tripartite motif containing 22
chr2_+_177053307 0.09 ENST00000331462.4
HOXD1
homeobox D1
chr14_-_36789865 0.09 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr1_-_114447683 0.09 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr1_+_117910047 0.09 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr10_+_124134201 0.09 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_-_49459865 0.09 ENST00000427987.1
AMT
aminomethyltransferase
chr2_-_240969906 0.08 ENST00000402971.2
OR6B2
olfactory receptor, family 6, subfamily B, member 2
chr1_-_54411255 0.08 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr5_+_121647877 0.08 ENST00000514497.2
ENST00000261367.7
SNCAIP
synuclein, alpha interacting protein
chr11_-_47546220 0.08 ENST00000528538.1
CELF1
CUGBP, Elav-like family member 1
chr11_-_65626797 0.08 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr8_-_10588010 0.08 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chrX_+_154114635 0.08 ENST00000369446.2
F8A1
coagulation factor VIII-associated 1
chr16_-_3422283 0.08 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr9_+_104161123 0.08 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chr3_-_58196939 0.08 ENST00000394549.2
ENST00000461914.3
DNASE1L3
deoxyribonuclease I-like 3
chr8_+_120428546 0.08 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr10_+_64564469 0.08 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr12_-_14721283 0.08 ENST00000240617.5
PLBD1
phospholipase B domain containing 1
chr21_+_44313375 0.08 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr13_+_37006421 0.08 ENST00000255465.4
CCNA1
cyclin A1
chr20_-_47804894 0.08 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr5_-_131826457 0.08 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr2_-_47168906 0.08 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr11_+_60635035 0.08 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr22_-_36925124 0.08 ENST00000457241.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr16_-_70713928 0.08 ENST00000576338.1
MTSS1L
metastasis suppressor 1-like
chr1_+_116519112 0.07 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr20_-_43589109 0.07 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr11_+_61717535 0.07 ENST00000534553.1
ENST00000301774.9
BEST1
bestrophin 1
chr20_+_4129496 0.07 ENST00000346595.2
SMOX
spermine oxidase
chr7_-_75241096 0.07 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr8_-_12612962 0.07 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr3_-_113464906 0.07 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_+_72794233 0.07 ENST00000335895.8
ENST00000380591.3
ENST00000507081.2
BTF3
basic transcription factor 3
chr6_+_36098363 0.07 ENST00000373759.1
MAPK13
mitogen-activated protein kinase 13
chr12_+_12966250 0.07 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr4_-_186347099 0.07 ENST00000505357.1
ENST00000264689.6
UFSP2
UFM1-specific peptidase 2
chr11_-_77123065 0.07 ENST00000530617.1
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr20_-_33543546 0.07 ENST00000216951.2
GSS
glutathione synthetase
chr4_-_48908737 0.07 ENST00000381464.2
OCIAD2
OCIA domain containing 2
chr18_+_34409069 0.07 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328
KIAA1328
chr12_+_69202795 0.07 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr5_+_121647386 0.07 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP
synuclein, alpha interacting protein
chr18_-_34409116 0.07 ENST00000334295.4
TPGS2
tubulin polyglutamylase complex subunit 2
chr1_-_155532484 0.07 ENST00000368346.3
ENST00000548830.1
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_114447763 0.07 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr10_+_96305610 0.07 ENST00000371332.4
ENST00000239026.6
HELLS
helicase, lymphoid-specific
chr11_+_100558384 0.06 ENST00000524892.2
ENST00000298815.8
ARHGAP42
Rho GTPase activating protein 42
chr6_+_76458990 0.06 ENST00000369977.3
MYO6
myosin VI
chr2_-_241759622 0.06 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr2_+_11295498 0.06 ENST00000295083.3
ENST00000441908.2
PQLC3
PQ loop repeat containing 3
chr19_-_55690758 0.06 ENST00000590851.1
SYT5
synaptotagmin V
chr6_+_4776580 0.06 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr8_-_23021533 0.06 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr6_-_138428613 0.06 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr12_+_99038998 0.06 ENST00000359972.2
ENST00000357310.1
ENST00000339433.3
ENST00000333991.1
APAF1
apoptotic peptidase activating factor 1
chr9_-_140115775 0.06 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr1_-_153588334 0.06 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr14_+_50999744 0.06 ENST00000441560.2
ATL1
atlastin GTPase 1
chr9_+_80912059 0.06 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr3_-_49459878 0.06 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr10_+_70661014 0.06 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr13_-_20735178 0.06 ENST00000241125.3
GJA3
gap junction protein, alpha 3, 46kDa
chr12_-_6451014 0.06 ENST00000366159.4
ENST00000539372.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr6_+_52285046 0.06 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr20_+_57467204 0.06 ENST00000603546.1
GNAS
GNAS complex locus
chr11_+_33279850 0.06 ENST00000531504.1
ENST00000456517.1
HIPK3
homeodomain interacting protein kinase 3
chr14_+_97263641 0.06 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr16_+_57406437 0.06 ENST00000564948.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr14_+_24702127 0.06 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr15_-_42386752 0.06 ENST00000290472.3
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chr4_+_71768043 0.06 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B
MOB kinase activator 1B
chr1_+_25599018 0.06 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr15_-_30685563 0.06 ENST00000401522.3
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr5_-_95297534 0.06 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr18_-_34408693 0.06 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr1_+_243419306 0.06 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr12_+_124086632 0.06 ENST00000238146.4
ENST00000538744.1
DDX55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr16_+_15744078 0.05 ENST00000396354.1
ENST00000570727.1
NDE1
nudE neurodevelopment protein 1
chr20_-_45035198 0.05 ENST00000372176.1
ELMO2
engulfment and cell motility 2
chr19_+_489140 0.05 ENST00000587541.1
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr15_-_102285913 0.05 ENST00000558592.1
RP11-89K11.1
Uncharacterized protein
chr5_+_141348755 0.05 ENST00000506004.1
ENST00000507291.1
RNF14
ring finger protein 14
chr1_+_42846443 0.05 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr11_-_59383617 0.05 ENST00000263847.1
OSBP
oxysterol binding protein
chr11_+_125757556 0.05 ENST00000526028.1
HYLS1
hydrolethalus syndrome 1
chr1_+_54411715 0.05 ENST00000371370.3
ENST00000371368.1
LRRC42
leucine rich repeat containing 42
chr1_+_54411995 0.05 ENST00000319223.4
ENST00000444987.1
LRRC42
leucine rich repeat containing 42
chr11_-_3078838 0.05 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr19_-_5567996 0.05 ENST00000448587.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr1_-_213189168 0.05 ENST00000366962.3
ENST00000360506.2
ANGEL2
angel homolog 2 (Drosophila)
chr4_-_10117949 0.05 ENST00000508079.1
WDR1
WD repeat domain 1
chr6_+_52285131 0.05 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_+_28206150 0.05 ENST00000456990.1
THEMIS2
thymocyte selection associated family member 2
chrX_-_70474377 0.05 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr22_-_36924944 0.05 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr2_-_37193606 0.05 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr10_+_126490354 0.05 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr1_+_151584544 0.05 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr19_+_18485509 0.05 ENST00000597765.1
GDF15
growth differentiation factor 15
chr1_-_110283138 0.05 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr6_+_24403144 0.05 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2
MRS2 magnesium transporter
chrX_+_134478706 0.05 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr1_-_54519134 0.05 ENST00000371341.1
TMEM59
transmembrane protein 59
chr15_+_41913690 0.05 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_+_25598872 0.05 ENST00000328664.4
RHD
Rh blood group, D antigen

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0031860 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS