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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFCP2

Z-value: 1.46

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Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
ENSG00000135457.5 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2hg19_v2_chr12_-_51566592_51566695-0.424.1e-01Click!

Activity profile of TFCP2 motif

Sorted Z-values of TFCP2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_61765315 1.14 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr4_+_26859300 0.93 ENST00000494628.2
stromal interaction molecule 2
chr2_-_61765732 0.87 ENST00000443240.1
ENST00000436018.1
exportin 1 (CRM1 homolog, yeast)
chr4_-_129207942 0.82 ENST00000503588.1
progesterone receptor membrane component 2
chr14_-_71107921 0.80 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chrX_-_119693745 0.79 ENST00000371323.2
cullin 4B
chr10_+_6625605 0.77 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr1_+_206623784 0.73 ENST00000426388.1
SLIT-ROBO Rho GTPase activating protein 2
chr8_+_95731904 0.63 ENST00000522422.1
dpy-19-like 4 (C. elegans)
chr1_-_145382434 0.62 ENST00000610154.1
RP11-458D21.1
chr4_-_129208030 0.57 ENST00000503872.1
progesterone receptor membrane component 2
chr11_-_85430088 0.56 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr5_-_132362226 0.55 ENST00000509437.1
ENST00000355372.2
ENST00000513541.1
ENST00000509008.1
ENST00000513848.1
ENST00000504170.1
ENST00000324170.3
zinc finger, CCHC domain containing 10
chr11_-_96123022 0.55 ENST00000542662.1
coiled-coil domain containing 82
chr8_-_95487272 0.55 ENST00000297592.5
RAD54 homolog B (S. cerevisiae)
chr2_+_189156389 0.55 ENST00000409843.1
GULP, engulfment adaptor PTB domain containing 1
chr14_-_68157084 0.54 ENST00000557564.1
RP11-1012A1.4
chr14_+_32547434 0.54 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr8_-_17533838 0.53 ENST00000400046.1
microtubule associated tumor suppressor 1
chr11_+_65265141 0.52 ENST00000534336.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr14_-_106069247 0.52 ENST00000479229.1
RP11-731F5.1
chr1_+_86889769 0.52 ENST00000370565.4
chloride channel accessory 2
chr1_-_145382362 0.51 ENST00000419817.1
ENST00000421937.3
ENST00000433081.2
RP11-458D21.1
chr1_-_221915418 0.51 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr3_-_113464906 0.50 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_55277692 0.50 ENST00000394611.2
reticulon 4
chr4_-_153274078 0.49 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_67584523 0.49 ENST00000521409.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_105937068 0.49 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr2_-_55277654 0.47 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr12_+_72061563 0.47 ENST00000551238.1
THAP domain containing, apoptosis associated protein 2
chr11_+_47270475 0.47 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chr7_-_120497178 0.46 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr15_+_63682335 0.46 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
chr6_-_84937314 0.45 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr19_+_507299 0.45 ENST00000359315.5
tubulin polyglutamylase complex subunit 1
chr6_+_63921351 0.44 ENST00000370659.1
FK506 binding protein 1C
chr16_+_67193834 0.43 ENST00000258200.3
ENST00000518148.1
ENST00000519917.1
ENST00000517382.1
ENST00000521920.1
F-box and leucine-rich repeat protein 8
chr2_+_172290707 0.43 ENST00000375255.3
ENST00000539783.1
DDB1 and CUL4 associated factor 17
chr12_+_42725554 0.42 ENST00000546750.1
ENST00000547847.1
periphilin 1
chr22_-_31742218 0.42 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_164528866 0.42 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr18_+_61575200 0.41 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr8_-_80680078 0.41 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr5_+_65222384 0.41 ENST00000380943.2
ENST00000416865.2
ENST00000380939.2
ENST00000380936.1
ENST00000380935.1
erbb2 interacting protein
chr11_-_85430163 0.40 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr1_+_117963209 0.40 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr15_-_42565221 0.39 ENST00000563371.1
ENST00000568400.1
ENST00000568432.1
transmembrane protein 87A
chrX_+_105936982 0.38 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr15_-_42565023 0.38 ENST00000566474.1
transmembrane protein 87A
chr17_+_7608511 0.38 ENST00000226091.2
ephrin-B3
chr10_+_64133934 0.38 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr3_-_42845922 0.38 ENST00000452906.2
HIG1 hypoxia inducible domain family, member 1A
chr19_-_11849697 0.37 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
zinc finger protein 823
chr9_-_21995249 0.37 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr10_-_33625154 0.37 ENST00000265371.4
neuropilin 1
chr8_-_95487331 0.37 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr1_+_87797351 0.37 ENST00000370542.1
LIM domain only 4
chr5_+_65222500 0.37 ENST00000511297.1
ENST00000506030.1
erbb2 interacting protein
chr9_+_125703282 0.36 ENST00000373647.4
ENST00000402311.1
RAB GTPase activating protein 1
chr5_+_136070614 0.36 ENST00000502421.1
CTB-1I21.1
chr12_-_118796910 0.36 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr2_+_238395042 0.36 ENST00000429898.1
ENST00000410032.1
melanophilin
chr2_+_238395879 0.36 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
melanophilin
chr3_+_108321623 0.35 ENST00000497905.1
ENST00000463306.1
DAZ interacting zinc finger protein 3
chrX_+_119737806 0.35 ENST00000371317.5
malignant T cell amplified sequence 1
chr5_+_65222438 0.34 ENST00000380938.2
erbb2 interacting protein
chr2_-_55277512 0.34 ENST00000402434.2
reticulon 4
chr8_-_103250997 0.34 ENST00000522368.1
ribonucleotide reductase M2 B (TP53 inducible)
chr16_-_20817753 0.33 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI1 exoribonuclease family member 2
chr5_-_39219705 0.33 ENST00000351578.6
FYN binding protein
chr3_-_113465065 0.33 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_+_128702969 0.33 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chr12_+_41086215 0.33 ENST00000547702.1
ENST00000551424.1
contactin 1
chr1_-_236046872 0.33 ENST00000536965.1
lysosomal trafficking regulator
chr6_+_142623758 0.33 ENST00000541199.1
ENST00000435011.2
G protein-coupled receptor 126
chr10_-_76995675 0.32 ENST00000469299.1
catechol-O-methyltransferase domain containing 1
chr6_+_142623063 0.32 ENST00000296932.8
ENST00000367609.3
G protein-coupled receptor 126
chr2_-_55277436 0.32 ENST00000354474.6
reticulon 4
chr6_-_73935163 0.32 ENST00000370388.3
KH homology domain containing 1-like
chr1_-_229644034 0.31 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
nucleoporin 133kDa
chr17_-_42991062 0.31 ENST00000587997.1
glial fibrillary acidic protein
chr6_+_155470243 0.31 ENST00000456877.2
ENST00000528391.2
T-cell lymphoma invasion and metastasis 2
chr19_-_57678811 0.30 ENST00000554048.2
double homeobox A
chr12_-_118796971 0.30 ENST00000542902.1
TAO kinase 3
chr19_-_12146483 0.30 ENST00000455504.2
ENST00000547560.1
ENST00000552904.1
ENST00000419886.2
ENST00000550507.1
ENST00000344980.6
ENST00000550745.1
ENST00000411841.1
zinc finger protein 433
chr2_-_152146385 0.30 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr6_+_3000195 0.29 ENST00000338130.2
NAD(P)H dehydrogenase, quinone 2
chr22_+_24199044 0.29 ENST00000403208.3
ENST00000398356.2
solute carrier family 2 (facilitated glucose transporter), member 11
chrX_+_123095890 0.29 ENST00000435215.1
stromal antigen 2
chr17_-_5138099 0.28 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chrX_-_72434628 0.28 ENST00000536638.1
ENST00000373517.3
nucleosome assembly protein 1-like 2
chr14_-_24685246 0.28 ENST00000396833.2
ENST00000288087.7
magnesium-dependent phosphatase 1
chr8_-_54755459 0.28 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr20_-_5591626 0.28 ENST00000379019.4
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr5_-_148930960 0.28 ENST00000261798.5
ENST00000377843.2
casein kinase 1, alpha 1
chr1_-_27709816 0.28 ENST00000374030.1
CD164 sialomucin-like 2
chr12_+_57522692 0.28 ENST00000554174.1
low density lipoprotein receptor-related protein 1
chr16_+_57653989 0.28 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr2_-_71222466 0.27 ENST00000606025.1
Uncharacterized protein
chr1_-_85040090 0.27 ENST00000370630.5
chitobiase, di-N-acetyl-
chrX_+_133507327 0.27 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
PHD finger protein 6
chr6_+_3000218 0.27 ENST00000380441.1
ENST00000380455.4
ENST00000380454.4
NAD(P)H dehydrogenase, quinone 2
chr1_-_54304212 0.27 ENST00000540001.1
NDC1 transmembrane nucleoporin
chr5_-_39219641 0.26 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr11_-_28129656 0.26 ENST00000263181.6
kinesin family member 18A
chr3_+_152552685 0.26 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr2_+_63277927 0.26 ENST00000282549.2
orthodenticle homeobox 1
chr1_-_39325431 0.26 ENST00000373001.3
Ras-related GTP binding C
chr4_+_170581213 0.26 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr19_+_38826415 0.25 ENST00000410018.1
ENST00000409235.3
catsper channel auxiliary subunit gamma
chr20_-_46415297 0.25 ENST00000467815.1
ENST00000359930.4
sulfatase 2
chr5_-_111093406 0.25 ENST00000379671.3
neuronal regeneration related protein
chr2_+_103089756 0.25 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr5_-_111093167 0.25 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr20_-_46415341 0.24 ENST00000484875.1
ENST00000361612.4
sulfatase 2
chr17_-_7082861 0.24 ENST00000269299.3
asialoglycoprotein receptor 1
chr2_-_188378368 0.24 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_56150184 0.24 ENST00000394554.1
EGF containing fibulin-like extracellular matrix protein 1
chr18_-_54305658 0.24 ENST00000586262.1
ENST00000217515.6
thioredoxin-like 1
chr16_+_78133293 0.24 ENST00000566780.1
WW domain containing oxidoreductase
chr8_-_28243934 0.24 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
zinc finger protein 395
chr11_+_47270436 0.24 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr12_-_76478446 0.23 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr20_+_11873141 0.23 ENST00000422390.1
BTB (POZ) domain containing 3
chr19_-_37019136 0.23 ENST00000592282.1
zinc finger protein 260
chr11_-_18956556 0.23 ENST00000302797.3
MAS-related GPR, member X1
chr14_+_75746781 0.23 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr20_+_34042962 0.23 ENST00000446710.1
ENST00000420564.1
centrosomal protein 250kDa
chr6_+_64282447 0.22 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr5_-_148930731 0.22 ENST00000515748.2
casein kinase 1, alpha 1
chr5_+_65222299 0.22 ENST00000284037.5
erbb2 interacting protein
chr22_-_37571089 0.22 ENST00000453962.1
ENST00000429622.1
ENST00000445595.1
interleukin 2 receptor, beta
chr1_-_67600639 0.22 ENST00000544837.1
ENST00000603691.1
chromosome 1 open reading frame 141
chr6_-_8102714 0.21 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr12_+_41086297 0.21 ENST00000551295.2
contactin 1
chr19_-_3600549 0.21 ENST00000589966.1
thromboxane A2 receptor
chr4_-_99850243 0.20 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr5_+_32711829 0.20 ENST00000415167.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_+_114271251 0.20 ENST00000375490.5
RNA binding motif protein 7
chr8_-_36636676 0.20 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
chrX_+_133507283 0.20 ENST00000370803.3
PHD finger protein 6
chr8_+_120428546 0.20 ENST00000259526.3
nephroblastoma overexpressed
chrX_+_133941250 0.20 ENST00000445123.1
family with sequence similarity 122C
chr11_+_62649158 0.20 ENST00000539891.1
ENST00000536981.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr7_+_127233689 0.20 ENST00000265825.5
ENST00000420086.2
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr11_+_134225909 0.19 ENST00000533324.1
galactosidase, beta 1-like 2
chr11_+_28129795 0.19 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr5_-_111092873 0.19 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr16_-_82045049 0.19 ENST00000532128.1
ENST00000328945.5
short chain dehydrogenase/reductase family 42E, member 1
chr2_+_238395803 0.19 ENST00000264605.3
melanophilin
chr6_-_30181133 0.19 ENST00000454678.2
ENST00000434785.1
tripartite motif containing 26
chr3_+_107241783 0.19 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
bobby sox homolog (Drosophila)
chr1_+_160321120 0.19 ENST00000424754.1
nicastrin
chr4_-_157892055 0.19 ENST00000422544.2
platelet derived growth factor C
chr11_+_114271314 0.19 ENST00000541475.1
RNA binding motif protein 7
chr5_-_37371163 0.19 ENST00000513532.1
nucleoporin 155kDa
chr12_+_6561190 0.18 ENST00000544021.1
ENST00000266556.7
TAP binding protein-like
chr2_+_240684554 0.18 ENST00000407524.1
Uncharacterized protein
chr2_-_85555355 0.18 ENST00000282120.2
ENST00000398263.2
trans-golgi network protein 2
chr14_+_74815116 0.18 ENST00000256362.4
vertebrae development associated
chr14_-_82089405 0.18 ENST00000554211.1
RP11-799P8.1
chr5_+_110427983 0.18 ENST00000513710.2
ENST00000505303.1
WD repeat domain 36
chr14_-_23451467 0.17 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chrX_-_46759138 0.17 ENST00000377879.3
chromosome X open reading frame 31
chr4_-_107237340 0.17 ENST00000394706.3
TBC1 domain containing kinase
chrX_-_118925600 0.17 ENST00000361575.3
ribosomal protein L39
chr17_-_7137582 0.17 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr4_+_166794383 0.17 ENST00000061240.2
ENST00000507499.1
tolloid-like 1
chr5_+_54455946 0.17 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr2_+_200820269 0.17 ENST00000392290.1
chromosome 2 open reading frame 47
chr5_-_36242119 0.17 ENST00000511088.1
ENST00000282512.3
ENST00000506945.1
NAD kinase 2, mitochondrial
chr5_+_140782351 0.17 ENST00000573521.1
protocadherin gamma subfamily A, 9
chr13_+_52586517 0.16 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr17_+_38474489 0.16 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chr4_-_107237374 0.16 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBC1 domain containing kinase
chr22_+_45898712 0.16 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
fibulin 1
chr16_-_3545424 0.16 ENST00000437192.3
ENST00000399645.3
chromosome 16 open reading frame 90
chr2_+_191792376 0.16 ENST00000409428.1
ENST00000409215.1
glutaminase
chr11_+_31391381 0.16 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr4_-_174255536 0.16 ENST00000446922.2
high mobility group box 2
chr22_+_24199113 0.15 ENST00000405847.1
solute carrier family 2 (facilitated glucose transporter), member 11
chr5_-_37371278 0.15 ENST00000231498.3
nucleoporin 155kDa
chr3_-_142297668 0.15 ENST00000350721.4
ENST00000383101.3
ataxia telangiectasia and Rad3 related
chr17_-_33905521 0.15 ENST00000225873.4
peroxisomal biogenesis factor 12
chr1_+_45212051 0.15 ENST00000372222.3
kinesin family member 2C
chr19_+_38826477 0.15 ENST00000409410.2
ENST00000215069.4
catsper channel auxiliary subunit gamma
chr15_+_59903975 0.15 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_+_2841433 0.15 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
zinc finger protein 555
chr5_+_61708582 0.15 ENST00000325324.6
importin 11
chr10_+_134232503 0.14 ENST00000428814.1
RP11-432J24.2
chr16_+_28770025 0.14 ENST00000435324.2
nuclear pore complex interacting protein family, member B9
chr3_-_42845951 0.14 ENST00000418900.2
ENST00000430190.1
HIG1 hypoxia inducible domain family, member 1A
chr17_+_73780852 0.14 ENST00000589666.1
unkempt family zinc finger
chr4_-_170533723 0.14 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NIMA-related kinase 1
chr19_+_17326521 0.14 ENST00000593597.1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr18_+_20494078 0.14 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr4_+_113218497 0.14 ENST00000458497.1
ENST00000177648.9
ENST00000504176.2
alpha-kinase 1
chr4_-_157892498 0.14 ENST00000502773.1
platelet derived growth factor C
chr11_+_114270752 0.14 ENST00000540163.1
RNA binding motif protein 7

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.7 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 1.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.6 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 0.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.5 GO:0060266 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.5 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.4 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) regulation of penile erection(GO:0060405)
0.1 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 0.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442) regulation of stem cell division(GO:2000035)
0.0 0.3 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.9 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0051531 NFAT protein import into nucleus(GO:0051531) positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.3 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 1.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 2.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0032396 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0032405 MutLalpha complex binding(GO:0032405)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.2 GO:0003707 steroid hormone receptor activity(GO:0003707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.9 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 2.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules