Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for TFAP2E

Z-value: 0.35

Motif logo

logo of

Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.6 transcription factor AP-2 epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg19_v2_chr1_+_36038971_36038971-0.749.1e-02Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_23810903 0.30 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr8_+_22250334 0.20 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr20_+_36888551 0.17 ENST00000418004.1
ENST00000451435.1
BPI
bactericidal/permeability-increasing protein
chr9_-_34662651 0.15 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr12_-_15942309 0.14 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_231175964 0.13 ENST00000366654.4
FAM89A
family with sequence similarity 89, member A
chr11_-_82612549 0.12 ENST00000528082.1
ENST00000533126.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr19_-_35981358 0.11 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr3_+_50192833 0.11 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_-_15942503 0.11 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_104068312 0.10 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr1_+_104068562 0.10 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr2_-_45236540 0.10 ENST00000303077.6
SIX2
SIX homeobox 2
chr12_+_53443963 0.10 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_+_38893047 0.10 ENST00000272252.5
GALM
galactose mutarotase (aldose 1-epimerase)
chr20_-_30539773 0.09 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr6_+_292051 0.09 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr12_+_75784850 0.09 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr16_-_72698834 0.08 ENST00000570152.1
ENST00000561611.2
ENST00000570035.1
AC004158.2
AC004158.2
chr22_+_22676808 0.08 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr7_+_100464760 0.08 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr17_+_72428218 0.08 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_74070853 0.07 ENST00000329003.3
GALR2
galanin receptor 2
chr11_-_82612727 0.07 ENST00000531128.1
ENST00000535099.1
ENST00000527444.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr10_-_98273668 0.07 ENST00000357947.3
TLL2
tolloid-like 2
chr6_+_13272904 0.07 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr9_+_19230433 0.07 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr11_-_82612678 0.07 ENST00000534631.1
ENST00000531801.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr19_+_3572925 0.07 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr2_-_174828892 0.07 ENST00000418194.2
SP3
Sp3 transcription factor
chrX_+_152990302 0.07 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr3_+_4535025 0.07 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_+_54960358 0.07 ENST00000439657.1
ENST00000376514.2
ENST00000376526.4
ENST00000436479.1
LENG8
leukocyte receptor cluster (LRC) member 8
chr4_-_82393052 0.07 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RASGEF1B
RasGEF domain family, member 1B
chr19_-_11039188 0.06 ENST00000588347.1
YIPF2
Yip1 domain family, member 2
chr11_+_63974135 0.06 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3
fermitin family member 3
chr6_-_88411911 0.06 ENST00000257787.5
AKIRIN2
akirin 2
chr11_-_65325430 0.06 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr2_+_241375069 0.06 ENST00000264039.2
GPC1
glypican 1
chr22_+_38146987 0.06 ENST00000418339.1
TRIOBP
TRIO and F-actin binding protein
chr3_-_48632593 0.06 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr11_-_61062762 0.05 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr3_+_105086056 0.05 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr19_-_11039261 0.05 ENST00000590329.1
ENST00000587943.1
ENST00000585858.1
ENST00000586748.1
ENST00000586575.1
ENST00000253031.2
YIPF2
Yip1 domain family, member 2
chr8_+_17780483 0.05 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
PCM1
pericentriolar material 1
chr19_-_39264072 0.05 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr10_-_98480243 0.05 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr5_-_179498703 0.05 ENST00000522208.2
RNF130
ring finger protein 130
chr11_+_118478313 0.05 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr5_-_179719048 0.05 ENST00000523583.1
ENST00000393360.3
ENST00000455781.1
ENST00000347470.4
ENST00000452135.2
ENST00000343111.6
MAPK9
mitogen-activated protein kinase 9
chr19_-_54676884 0.05 ENST00000376591.4
TMC4
transmembrane channel-like 4
chr19_-_54676846 0.04 ENST00000301187.4
TMC4
transmembrane channel-like 4
chr1_+_211433275 0.04 ENST00000367005.4
RCOR3
REST corepressor 3
chr9_-_21077939 0.04 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr17_+_36584662 0.04 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr15_+_23810853 0.04 ENST00000568252.1
MKRN3
makorin ring finger protein 3
chr6_+_42531798 0.04 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr8_+_17780346 0.04 ENST00000325083.8
PCM1
pericentriolar material 1
chr20_-_25371412 0.04 ENST00000339157.5
ENST00000376542.3
ABHD12
abhydrolase domain containing 12
chr2_-_177502254 0.04 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr1_+_901847 0.04 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr5_-_179499086 0.03 ENST00000261947.4
RNF130
ring finger protein 130
chr16_+_69600058 0.03 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_+_48423453 0.03 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2
xylosyltransferase II
chr13_-_76056250 0.03 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4
TBC1 domain family, member 4
chr12_-_65153175 0.03 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS
glucosamine (N-acetyl)-6-sulfatase
chr4_+_154387480 0.03 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr16_+_69599861 0.03 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_3572758 0.03 ENST00000416526.1
HMG20B
high mobility group 20B
chr17_+_40932610 0.03 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr17_+_37824217 0.03 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr16_+_69599899 0.03 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_24149977 0.02 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr1_+_17248418 0.02 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr10_+_99894380 0.02 ENST00000370584.3
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr19_-_10613862 0.02 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr19_+_38794797 0.02 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr14_-_64010046 0.02 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_+_37824411 0.02 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr1_-_201346761 0.02 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr7_-_100065686 0.02 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr1_+_233749739 0.02 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr1_-_114355083 0.02 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr10_-_112678904 0.02 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr17_-_42188598 0.02 ENST00000591714.1
HDAC5
histone deacetylase 5
chrX_+_131157322 0.02 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4
Serine/threonine-protein kinase MST4
chr3_+_155860751 0.02 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr2_+_74741569 0.01 ENST00000233638.7
TLX2
T-cell leukemia homeobox 2
chr20_+_55205825 0.01 ENST00000544508.1
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr10_+_99894399 0.01 ENST00000298999.3
ENST00000314594.5
R3HCC1L
R3H domain and coiled-coil containing 1-like
chr19_+_4969116 0.01 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
KDM4B
lysine (K)-specific demethylase 4B
chr2_+_38893208 0.01 ENST00000410063.1
GALM
galactose mutarotase (aldose 1-epimerase)
chr13_-_27334879 0.01 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chrX_+_131157290 0.01 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr19_-_46389359 0.01 ENST00000302165.3
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr20_+_58508817 0.01 ENST00000358293.3
FAM217B
family with sequence similarity 217, member B
chr5_-_179499108 0.01 ENST00000521389.1
RNF130
ring finger protein 130
chr7_-_129251459 0.01 ENST00000608694.1
RP11-448A19.1
RP11-448A19.1
chrX_+_49028265 0.01 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr10_-_108924284 0.01 ENST00000344440.6
ENST00000263054.6
SORCS1
sortilin-related VPS10 domain containing receptor 1
chr11_-_35441524 0.01 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_140624499 0.01 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr11_-_66056596 0.01 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chrX_-_118826784 0.01 ENST00000394616.4
SEPT6
septin 6
chr6_+_37787262 0.00 ENST00000287218.4
ZFAND3
zinc finger, AN1-type domain 3
chr12_+_53773944 0.00 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr17_-_31620006 0.00 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr4_-_101439242 0.00 ENST00000296420.4
EMCN
endomucin
chr11_-_6633799 0.00 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr11_+_82612740 0.00 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82
chromosome 11 open reading frame 82
chr3_-_55521323 0.00 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chrX_+_51636629 0.00 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr17_+_29158962 0.00 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr11_-_71753188 0.00 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr17_-_42992856 0.00 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.2 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.0 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway