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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 1.00

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_134210276-0.207.1e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_81902791 0.75 ENST00000557055.1
stonin 2
chr3_-_182833863 0.64 ENST00000492597.1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr9_-_3469181 0.53 ENST00000366116.2
Uncharacterized protein
chr6_-_41673552 0.51 ENST00000419574.1
ENST00000445214.1
transcription factor EB
chr5_-_42811986 0.46 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr1_-_116926718 0.45 ENST00000598661.1
Uncharacterized protein
chr2_+_86116396 0.45 ENST00000455121.3
AC105053.4
chr8_-_30013748 0.45 ENST00000607315.1
RP11-51J9.5
chrX_-_106960285 0.43 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chrX_-_108868390 0.42 ENST00000372101.2
KCNE1-like
chr1_-_205391178 0.41 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr4_-_89442940 0.40 ENST00000527353.1
phosphatidylinositol glycan anchor biosynthesis, class Y
chr3_-_156840776 0.40 ENST00000471357.1
long intergenic non-protein coding RNA 880
chr14_-_50154921 0.38 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr21_-_38338773 0.38 ENST00000399120.1
ENST00000419461.1
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr4_-_142253761 0.37 ENST00000511213.1
RP11-362F19.1
chr8_-_95961578 0.36 ENST00000448464.2
ENST00000342697.4
tumor protein p53 inducible nuclear protein 1
chrX_-_78622805 0.36 ENST00000373298.2
integral membrane protein 2A
chr11_+_117103333 0.36 ENST00000534428.1
ring finger protein 214
chr11_+_31531291 0.36 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr3_-_49058479 0.36 ENST00000440857.1
DALR anticodon binding domain containing 3
chr8_-_12293852 0.35 ENST00000262365.4
ENST00000351291.4
ENST00000309608.5
ENST00000527331.1
ENST00000532480.1
ENST00000393715.3
family with sequence similarity 86, member B2
chr2_+_171627597 0.35 ENST00000429172.1
ENST00000426475.1
AC007405.6
chr12_-_105352047 0.34 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
solute carrier family 41 (magnesium transporter), member 2
chr11_-_82997371 0.34 ENST00000525503.1
coiled-coil domain containing 90B
chr20_-_23030296 0.33 ENST00000377103.2
thrombomodulin
chr4_-_123843597 0.33 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr19_-_43702231 0.33 ENST00000597374.1
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr16_+_56703703 0.33 ENST00000332374.4
metallothionein 1H
chr2_+_54198210 0.32 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr8_-_99837856 0.32 ENST00000518165.1
ENST00000419617.2
serine/threonine kinase 3
chr9_-_33447584 0.32 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr8_-_92053212 0.31 ENST00000285419.3
transmembrane protein 55A
chr6_+_90272488 0.30 ENST00000485637.1
ENST00000522705.1
ankyrin repeat domain 6
chr5_-_59995921 0.30 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEP domain containing 1B
chr4_+_106816592 0.30 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
nephronectin
chr4_+_106816644 0.29 ENST00000506666.1
ENST00000503451.1
nephronectin
chrX_+_15756382 0.29 ENST00000318636.3
carbonic anhydrase VB, mitochondrial
chr16_-_3422283 0.28 ENST00000399974.3
MT-RNR2-like 4
chr19_-_52408285 0.28 ENST00000596690.1
zinc finger protein 649
chr12_+_16500599 0.28 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr3_-_168864315 0.27 ENST00000475754.1
ENST00000484519.1
MDS1 and EVI1 complex locus
chr5_-_142784003 0.26 ENST00000416954.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_55276320 0.26 ENST00000357376.3
reticulon 4
chr12_+_72233487 0.26 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr12_+_16500571 0.25 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr3_+_179065474 0.25 ENST00000471841.1
ENST00000280653.7
mitofusin 1
chr11_-_59633951 0.25 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr7_+_150413645 0.25 ENST00000307194.5
GTPase, IMAP family member 1
chr10_+_60094735 0.25 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr3_-_176915215 0.25 ENST00000457928.2
ENST00000422442.1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_92414952 0.25 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr10_-_79398250 0.25 ENST00000286627.5
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr8_-_71519889 0.25 ENST00000521425.1
translocation associated membrane protein 1
chr10_+_98592009 0.24 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chr1_-_150669500 0.24 ENST00000271732.3
golgi phosphoprotein 3-like
chr1_+_46859933 0.24 ENST00000243167.8
fatty acid amide hydrolase
chr7_-_99569468 0.24 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr1_-_8000872 0.23 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr5_+_139055021 0.23 ENST00000502716.1
ENST00000503511.1
CXXC finger protein 5
chr2_+_232575168 0.23 ENST00000440384.1
prothymosin, alpha
chr6_+_30585486 0.23 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr2_+_56179262 0.22 ENST00000606639.1
RP11-481J13.1
chr11_+_58910295 0.22 ENST00000420244.1
family with sequence similarity 111, member A
chr11_+_58910201 0.22 ENST00000528737.1
family with sequence similarity 111, member A
chr4_-_153303658 0.22 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_-_105352080 0.22 ENST00000433540.1
solute carrier family 41 (magnesium transporter), member 2
chr9_+_2029019 0.22 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_12726623 0.22 ENST00000439721.1
ADP-ribosylation factor-like 4A
chr11_+_1855645 0.22 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr11_+_33061543 0.22 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr4_+_169633310 0.22 ENST00000510998.1
palladin, cytoskeletal associated protein
chr13_-_64650144 0.21 ENST00000456627.1
long intergenic non-protein coding RNA 355
chr12_+_69201923 0.21 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr2_+_63816126 0.21 ENST00000454035.1
malate dehydrogenase 1, NAD (soluble)
chr5_+_170288856 0.21 ENST00000523189.1
RAN binding protein 17
chr16_+_56970567 0.21 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_-_52912901 0.21 ENST00000551188.1
keratin 5
chr4_+_95972822 0.21 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr21_+_17791648 0.21 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr4_-_123844084 0.20 ENST00000339154.2
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr15_+_89787180 0.20 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
Fanconi anemia, complementation group I
chr2_-_234763105 0.20 ENST00000454020.1
Holliday junction recognition protein
chr14_-_53258180 0.20 ENST00000554230.1
glucosamine-phosphate N-acetyltransferase 1
chr5_+_139055055 0.20 ENST00000511457.1
CXXC finger protein 5
chr12_-_68845417 0.20 ENST00000542875.1
RP11-81H14.2
chr1_+_78354175 0.20 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
nexilin (F actin binding protein)
chr5_+_68462837 0.20 ENST00000256442.5
cyclin B1
chr7_+_99102573 0.20 ENST00000394170.2
zinc finger with KRAB and SCAN domains 5
chr3_-_52869205 0.20 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr11_-_14913765 0.19 ENST00000334636.5
cytochrome P450, family 2, subfamily R, polypeptide 1
chr2_-_17981462 0.19 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr10_+_118349920 0.19 ENST00000531984.1
pancreatic lipase-related protein 1
chr5_+_68462944 0.19 ENST00000506572.1
cyclin B1
chr5_+_68463043 0.19 ENST00000508407.1
ENST00000505500.1
cyclin B1
chr19_-_4535233 0.19 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr3_+_145782358 0.19 ENST00000422482.1
HCG1786590; PRO2533; Uncharacterized protein
chr11_+_1892102 0.18 ENST00000417766.1
lymphocyte-specific protein 1
chr2_-_3595547 0.18 ENST00000438485.1
Uncharacterized protein
chr12_-_50677255 0.18 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr21_-_38362497 0.18 ENST00000427746.1
ENST00000336648.4
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr1_+_78354330 0.18 ENST00000440324.1
nexilin (F actin binding protein)
chr20_-_52790055 0.18 ENST00000395955.3
cytochrome P450, family 24, subfamily A, polypeptide 1
chr17_-_63052929 0.18 ENST00000439174.2
guanine nucleotide binding protein (G protein), alpha 13
chrX_-_150067069 0.18 ENST00000466436.1
CD99 molecule-like 2
chr20_-_46415297 0.18 ENST00000467815.1
ENST00000359930.4
sulfatase 2
chr6_+_155470243 0.18 ENST00000456877.2
ENST00000528391.2
T-cell lymphoma invasion and metastasis 2
chr12_-_123634449 0.17 ENST00000542210.1
phosphatidylinositol transfer protein, membrane-associated 2
chr11_-_82997013 0.17 ENST00000529073.1
ENST00000529611.1
coiled-coil domain containing 90B
chr20_-_23402028 0.17 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
N-ethylmaleimide-sensitive factor attachment protein, beta
chr16_+_83932684 0.17 ENST00000262430.4
malonyl-CoA decarboxylase
chr15_-_42749711 0.17 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr17_+_16593539 0.17 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
coiled-coil domain containing 144A
chr6_-_33160231 0.17 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr3_-_52860850 0.17 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr11_-_14913190 0.17 ENST00000532378.1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr11_+_117103441 0.17 ENST00000531287.1
ENST00000531452.1
ring finger protein 214
chr16_-_3306587 0.16 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr19_-_46288917 0.16 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chr8_-_72274095 0.16 ENST00000303824.7
eyes absent homolog 1 (Drosophila)
chr13_+_41635617 0.16 ENST00000542082.1
WW domain binding protein 4
chr10_-_12084770 0.16 ENST00000357604.5
UPF2 regulator of nonsense transcripts homolog (yeast)
chr16_-_5147743 0.16 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
family with sequence similarity 86, member A
chr5_-_179050066 0.16 ENST00000329433.6
ENST00000510411.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr5_+_95066823 0.16 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr9_-_99637820 0.16 ENST00000289032.8
ENST00000535338.1
zinc finger protein 782
chr11_+_1874200 0.16 ENST00000311604.3
lymphocyte-specific protein 1
chr18_+_39535239 0.16 ENST00000585528.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr2_-_234763147 0.16 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
Holliday junction recognition protein
chr17_+_71229346 0.16 ENST00000535032.2
ENST00000582793.1
chromosome 17 open reading frame 80
chr13_+_51483814 0.16 ENST00000336617.3
ENST00000422660.1
ribonuclease H2, subunit B
chr2_-_191115229 0.16 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr2_+_113321939 0.16 ENST00000458012.2
polymerase (RNA) I polypeptide B, 128kDa
chr11_+_125496619 0.16 ENST00000532669.1
ENST00000278916.3
checkpoint kinase 1
chr10_-_28571015 0.15 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr7_+_99102267 0.15 ENST00000326775.5
ENST00000451158.1
zinc finger with KRAB and SCAN domains 5
chr1_+_153600869 0.15 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr4_+_186347388 0.15 ENST00000511138.1
ENST00000511581.1
chromosome 4 open reading frame 47
chr1_-_31230650 0.15 ENST00000294507.3
lysosomal protein transmembrane 5
chr1_+_78354297 0.15 ENST00000334785.7
nexilin (F actin binding protein)
chr1_+_51701924 0.15 ENST00000242719.3
ring finger protein 11
chr14_-_91282726 0.15 ENST00000328459.6
ENST00000357056.2
tetratricopeptide repeat domain 7B
chr1_-_167522982 0.15 ENST00000370509.4
cellular repressor of E1A-stimulated genes 1
chr17_-_15165854 0.15 ENST00000395936.1
ENST00000395938.2
peripheral myelin protein 22
chr11_-_62457371 0.15 ENST00000317449.4
LRRN4 C-terminal like
chr2_+_63816295 0.14 ENST00000539945.1
ENST00000544381.1
malate dehydrogenase 1, NAD (soluble)
chr12_-_10282742 0.14 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr1_-_9129598 0.14 ENST00000535586.1
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr20_+_34802295 0.14 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr16_-_832926 0.14 ENST00000293892.3
mesothelin-like
chr4_+_37892682 0.14 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_+_71228793 0.14 ENST00000426147.2
chromosome 17 open reading frame 80
chr18_-_47376197 0.14 ENST00000592688.1
myosin VB
chr5_+_49963239 0.14 ENST00000505554.1
poly (ADP-ribose) polymerase family, member 8
chr2_+_234602305 0.14 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr4_+_26165074 0.14 ENST00000512351.1
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_20462783 0.14 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
acyl-CoA synthetase medium-chain family member 2A
chr1_-_150669604 0.14 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr4_-_24914576 0.14 ENST00000502801.1
ENST00000428116.2
coiled-coil domain containing 149
chr2_+_233562015 0.13 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr14_-_50559361 0.13 ENST00000305273.1
chromosome 14 open reading frame 183
chr1_+_202976493 0.13 ENST00000367242.3
transmembrane protein 183A
chr17_-_62499334 0.13 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_-_106054952 0.13 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr17_-_191188 0.13 ENST00000575634.1
rabphilin 3A-like (without C2 domains)
chr2_+_63816269 0.13 ENST00000432309.1
malate dehydrogenase 1, NAD (soluble)
chr12_+_9142131 0.13 ENST00000356986.3
ENST00000266551.4
killer cell lectin-like receptor subfamily G, member 1
chr6_+_10528560 0.13 ENST00000379597.3
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr11_-_74660065 0.13 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
X-ray radiation resistance associated 1
chr3_-_184971817 0.13 ENST00000440662.1
ENST00000456310.1
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr17_+_71228740 0.13 ENST00000268942.8
ENST00000359042.2
chromosome 17 open reading frame 80
chr6_+_90272027 0.13 ENST00000522441.1
ankyrin repeat domain 6
chr2_-_75745823 0.13 ENST00000452003.1
eva-1 homolog A (C. elegans)
chrX_-_107334790 0.13 ENST00000217958.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr6_+_143771934 0.13 ENST00000367592.1
peroxisomal biogenesis factor 3
chr11_-_108422926 0.12 ENST00000428840.1
ENST00000526312.1
exophilin 5
chr5_-_142784101 0.12 ENST00000503201.1
ENST00000502892.1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_63816087 0.12 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
malate dehydrogenase 1, NAD (soluble)
chr12_-_66035922 0.12 ENST00000546198.1
ENST00000535315.1
ENST00000537298.1
RP11-230G5.2
chr1_+_12524965 0.12 ENST00000471923.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chrX_-_16887963 0.12 ENST00000380084.4
retinoblastoma binding protein 7
chr13_-_50510622 0.12 ENST00000378195.2
SPRY domain containing 7
chr11_+_125496124 0.12 ENST00000533778.2
ENST00000534070.1
checkpoint kinase 1
chr3_+_101498269 0.12 ENST00000491511.2
neurexophilin and PC-esterase domain family, member 3
chrX_-_107334750 0.12 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_+_66205712 0.12 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr8_-_112248400 0.12 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr10_+_35415851 0.12 ENST00000374726.3
cAMP responsive element modulator
chr5_+_135364584 0.12 ENST00000442011.2
ENST00000305126.8
transforming growth factor, beta-induced, 68kDa
chr3_+_197677379 0.12 ENST00000442341.1
ribosomal protein L35a
chr4_+_114214125 0.12 ENST00000509550.1
ankyrin 2, neuronal
chr9_+_125137565 0.12 ENST00000373698.5
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr21_-_10990830 0.12 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
transmembrane phosphatase with tensin homology
chr10_+_52499682 0.12 ENST00000185907.9
ENST00000374006.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
chr11_+_14926543 0.12 ENST00000523376.1
calcitonin-related polypeptide beta
chr19_-_50528392 0.11 ENST00000600137.1
ENST00000597215.1
vaccinia related kinase 3
chr20_-_46415341 0.11 ENST00000484875.1
ENST00000361612.4
sulfatase 2
chr15_+_63796779 0.11 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
ubiquitin specific peptidase 3
chr3_-_184971853 0.11 ENST00000231887.3
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr6_+_28109703 0.11 ENST00000457389.2
ENST00000330236.6
zinc finger with KRAB and SCAN domains 8

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.6 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.3 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.5 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:2000525 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0046010 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) gastric mucosal blood circulation(GO:1990768) small intestine smooth muscle contraction(GO:1990770)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.0 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0009386 translational attenuation(GO:0009386)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.6 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.0 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)