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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for TBX5
Z-value: 0.31
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Transcription factors associated with TBX5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX5 | hg19_v2_chr12_-_114843889_114843921 | 0.28 | 5.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_2205352 Show fit | 0.20 |
ENST00000563192.1
|
RP11-304L19.5 |
|
| chr17_-_74533734 Show fit | 0.15 |
ENST00000589342.1
|
cytoglobin |
|
| chr20_-_4055812 Show fit | 0.14 |
ENST00000379526.1
|
Uncharacterized protein |
|
| chr11_+_7559485 Show fit | 0.14 |
ENST00000527790.1
|
PTPRF interacting protein, binding protein 2 (liprin beta 2) |
|
| chr19_-_8579030 Show fit | 0.13 |
ENST00000255616.8
ENST00000393927.4 |
zinc finger protein 414 |
|
| chr5_-_74348371 Show fit | 0.13 |
ENST00000503568.1
|
RP11-229C3.2 |
|
| chr17_+_37821593 Show fit | 0.13 |
ENST00000578283.1
|
titin-cap |
|
| chr5_-_176836577 Show fit | 0.11 |
ENST00000253496.3
|
coagulation factor XII (Hageman factor) |
|
| chr22_-_36013368 Show fit | 0.11 |
ENST00000442617.1
ENST00000397326.2 ENST00000397328.1 ENST00000451685.1 |
myoglobin |
|
| chr14_+_104177607 Show fit | 0.11 |
ENST00000429169.1
|
Uncharacterized protein; cDNA FLJ53535 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBX5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 0.0 | 0.1 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.0 | 0.1 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919) |
| 0.0 | 0.1 | GO:0060032 | notochord regression(GO:0060032) |
| 0.0 | 0.1 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.0 | 0.1 | GO:0034653 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037) |
| 0.0 | 0.1 | GO:0046668 | regulation of retinal cell programmed cell death(GO:0046668) |
| 0.0 | 0.1 | GO:0030311 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.0 | 0.1 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.0 | 0.1 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.0 | 0.1 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 0.0 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.0 | 0.1 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.0 | 0.1 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.0 | 0.1 | GO:0038131 | neuregulin receptor activity(GO:0038131) |
| 0.0 | 0.1 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.0 | 0.1 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.0 | 0.1 | GO:0033906 | protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906) |
| 0.0 | 0.0 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.0 | 0.0 | GO:0004968 | gonadotropin-releasing hormone receptor activity(GO:0004968) |
| 0.0 | 0.0 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |