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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX3

Z-value: 0.77

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
TBX3
ENSG00000135111.10 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg19_v2_chr12_-_115121962_115121987-0.542.7e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22766766 1.51 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr6_+_32821924 0.65 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr11_-_18258342 0.54 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr14_-_51863853 0.52 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr1_-_153085984 0.48 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr2_-_113594279 0.31 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_-_183560011 0.31 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr19_-_43835582 0.30 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr11_-_327537 0.27 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr20_+_34679725 0.27 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_+_327171 0.26 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr11_+_65082289 0.26 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_8075693 0.25 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr11_-_1619524 0.25 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr11_-_61849656 0.25 ENST00000524942.1
RP11-810P12.5
RP11-810P12.5
chr19_-_10679644 0.24 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr6_+_86195088 0.24 ENST00000437581.1
NT5E
5'-nucleotidase, ecto (CD73)
chr19_-_10679697 0.24 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr16_+_84801852 0.22 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr1_-_152552980 0.22 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr16_-_14726576 0.21 ENST00000562896.1
PARN
poly(A)-specific ribonuclease
chr1_-_153283194 0.21 ENST00000290722.1
PGLYRP3
peptidoglycan recognition protein 3
chr10_-_90611566 0.20 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr16_-_68057770 0.20 ENST00000332395.5
DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr1_-_119869846 0.20 ENST00000457719.1
RP11-418J17.3
RP11-418J17.3
chr2_-_202298268 0.19 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr6_-_11382478 0.19 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr3_-_46068969 0.19 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr14_+_90422867 0.18 ENST00000553989.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr15_-_43212836 0.18 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2
tau tubulin kinase 2
chr17_-_41132410 0.18 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr15_-_43212996 0.17 ENST00000567840.1
TTBK2
tau tubulin kinase 2
chr8_+_23386305 0.17 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr14_+_74416989 0.16 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr22_-_41258074 0.16 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr8_-_121825088 0.16 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr7_+_113091127 0.16 ENST00000433518.1
TSRM
Uncharacterized protein; Zinc finger domain-related protein TSRM
chr3_+_42897512 0.16 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr3_-_170626418 0.15 ENST00000474096.1
ENST00000295822.2
EIF5A2
eukaryotic translation initiation factor 5A2
chr6_-_32821599 0.15 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_+_50478977 0.15 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr7_-_2883928 0.15 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr17_-_26220366 0.15 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr7_-_93519471 0.15 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr15_-_74501310 0.14 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr19_-_3478477 0.14 ENST00000591708.1
C19orf77
chromosome 19 open reading frame 77
chr17_+_48351785 0.14 ENST00000507382.1
TMEM92
transmembrane protein 92
chr1_+_59522284 0.14 ENST00000449812.2
RP11-145M4.3
RP11-145M4.3
chr8_-_81083341 0.14 ENST00000519303.2
TPD52
tumor protein D52
chr11_+_34643600 0.14 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr19_+_55385731 0.13 ENST00000469767.1
ENST00000355524.3
ENST00000391725.3
ENST00000345937.4
ENST00000353758.4
ENST00000359272.4
ENST00000391723.3
ENST00000391724.3
FCAR
Fc fragment of IgA, receptor for
chr3_-_55539287 0.13 ENST00000472238.1
RP11-875H7.5
RP11-875H7.5
chr11_+_71238313 0.13 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr4_+_71384300 0.13 ENST00000504451.1
AMTN
amelotin
chr6_-_55443975 0.12 ENST00000308161.4
ENST00000398661.2
ENST00000274901.4
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr7_+_102389434 0.12 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr7_+_95401877 0.12 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr7_-_76255444 0.12 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr12_+_48876275 0.11 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr3_+_63638372 0.11 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chr5_+_40841410 0.11 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr3_+_52454971 0.11 ENST00000465863.1
PHF7
PHD finger protein 7
chrX_+_149887090 0.10 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr20_-_5931109 0.10 ENST00000203001.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr8_+_133931648 0.10 ENST00000519178.1
ENST00000542445.1
TG
thyroglobulin
chr4_+_169575875 0.10 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr12_+_1800179 0.10 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr11_-_62607036 0.10 ENST00000311713.7
ENST00000278856.4
WDR74
WD repeat domain 74
chr19_+_496454 0.10 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr1_+_159772121 0.10 ENST00000339348.5
ENST00000392235.3
ENST00000368106.3
FCRL6
Fc receptor-like 6
chr6_+_32146268 0.10 ENST00000427134.2
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr18_-_5544241 0.10 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr8_+_86851932 0.10 ENST00000517368.1
CTA-392E5.1
CTA-392E5.1
chr15_-_59665062 0.10 ENST00000288235.4
MYO1E
myosin IE
chr6_+_31021225 0.09 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr1_+_171750776 0.09 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr9_-_100954910 0.09 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr6_-_41254403 0.09 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1
triggering receptor expressed on myeloid cells 1
chr16_-_30381580 0.09 ENST00000409939.3
TBC1D10B
TBC1 domain family, member 10B
chr1_-_155959853 0.09 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr15_-_34635314 0.09 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr6_-_131277510 0.09 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr14_+_74111578 0.09 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chrX_-_65259914 0.09 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr7_-_99381798 0.09 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr11_+_118889142 0.08 ENST00000533632.1
TRAPPC4
trafficking protein particle complex 4
chr14_-_50087312 0.08 ENST00000298289.6
RPL36AL
ribosomal protein L36a-like
chr5_+_148521046 0.08 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chrX_-_131623043 0.08 ENST00000421707.1
MBNL3
muscleblind-like splicing regulator 3
chr5_-_135290651 0.08 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr4_-_85654615 0.08 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr12_-_56121612 0.08 ENST00000546939.1
CD63
CD63 molecule
chr20_-_5931051 0.08 ENST00000453074.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr12_-_56120865 0.08 ENST00000548898.1
ENST00000552067.1
CD63
CD63 molecule
chr1_+_212208919 0.08 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr6_+_30852738 0.08 ENST00000508312.1
ENST00000512336.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_-_71532207 0.08 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_+_77924204 0.08 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr9_+_117904097 0.08 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr11_-_27722021 0.08 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr11_-_122932730 0.07 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr14_-_74416829 0.07 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr16_+_72088376 0.07 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr6_-_46703092 0.07 ENST00000541026.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_+_41132564 0.07 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr19_-_51531272 0.07 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr10_+_60028818 0.07 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr15_-_38852251 0.07 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr6_+_30853002 0.07 ENST00000421124.2
ENST00000512725.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_242612726 0.07 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr10_-_104262426 0.07 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr6_-_33385655 0.07 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_-_71293921 0.07 ENST00000398530.1
KRTAP5-11
keratin associated protein 5-11
chr15_+_59665194 0.07 ENST00000560394.1
FAM81A
family with sequence similarity 81, member A
chr6_-_35888905 0.07 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr6_+_124125286 0.07 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
NKAIN2
Na+/K+ transporting ATPase interacting 2
chr7_+_98476095 0.07 ENST00000359863.4
ENST00000355540.3
TRRAP
transformation/transcription domain-associated protein
chr11_+_71259466 0.07 ENST00000528743.2
KRTAP5-9
keratin associated protein 5-9
chr10_+_51827648 0.07 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
FAM21A
family with sequence similarity 21, member A
chr5_+_139739772 0.07 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr18_+_5238055 0.07 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr22_+_24891210 0.07 ENST00000382760.2
UPB1
ureidopropionase, beta
chr6_-_55443831 0.07 ENST00000428842.1
ENST00000358072.5
ENST00000508459.1
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr19_+_39936207 0.06 ENST00000594729.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr4_+_40195262 0.06 ENST00000503941.1
RHOH
ras homolog family member H
chr19_-_42724261 0.06 ENST00000595337.1
DEDD2
death effector domain containing 2
chr10_+_94608218 0.06 ENST00000371543.1
EXOC6
exocyst complex component 6
chr20_-_1472053 0.06 ENST00000537284.1
SIRPB2
signal-regulatory protein beta 2
chr15_+_77713299 0.06 ENST00000559099.1
HMG20A
high mobility group 20A
chr19_-_51538118 0.06 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr5_-_39425222 0.06 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr9_+_104296243 0.06 ENST00000466817.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr17_+_45286387 0.06 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr12_+_7169887 0.06 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr2_-_24149918 0.06 ENST00000439915.1
ATAD2B
ATPase family, AAA domain containing 2B
chr11_-_122931881 0.06 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr19_-_51530916 0.06 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr14_+_21785693 0.06 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chrX_+_51942963 0.06 ENST00000375625.3
RP11-363G10.2
RP11-363G10.2
chr3_-_128207349 0.06 ENST00000487848.1
GATA2
GATA binding protein 2
chr4_-_183838747 0.06 ENST00000438320.2
DCTD
dCMP deaminase
chr14_+_70233810 0.06 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
SRSF5
serine/arginine-rich splicing factor 5
chr22_-_38480100 0.06 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr19_-_42931567 0.06 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr15_+_59664884 0.06 ENST00000558348.1
FAM81A
family with sequence similarity 81, member A
chr17_-_28661065 0.06 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr10_-_71176623 0.06 ENST00000373306.4
TACR2
tachykinin receptor 2
chr6_-_55443958 0.06 ENST00000370850.2
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr5_+_150040403 0.06 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr19_+_41257084 0.06 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr19_-_47735918 0.05 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr19_-_51531210 0.05 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr1_+_159770292 0.05 ENST00000536257.1
ENST00000321935.6
FCRL6
Fc receptor-like 6
chr2_+_114647617 0.05 ENST00000536059.1
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr12_-_56120838 0.05 ENST00000548160.1
CD63
CD63 molecule
chr15_+_77712993 0.05 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr6_-_128222103 0.05 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr20_-_1472121 0.05 ENST00000444444.2
SIRPB2
signal-regulatory protein beta 2
chr1_+_36396313 0.05 ENST00000324350.5
AGO3
argonaute RISC catalytic component 3
chr4_-_108641608 0.05 ENST00000265174.4
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr1_+_32608566 0.05 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr3_+_133293278 0.05 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chr15_+_74911430 0.05 ENST00000562670.1
ENST00000564096.1
CLK3
CDC-like kinase 3
chr17_+_43861680 0.05 ENST00000314537.5
CRHR1
corticotropin releasing hormone receptor 1
chr15_-_74504597 0.05 ENST00000416286.3
STRA6
stimulated by retinoic acid 6
chr12_-_8815404 0.05 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr15_+_40861487 0.05 ENST00000315616.7
ENST00000559271.1
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr20_-_44539538 0.05 ENST00000372420.1
PLTP
phospholipid transfer protein
chr4_-_69215699 0.05 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr19_-_16682987 0.05 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1
solute carrier family 35, member E1
chr2_+_242167319 0.05 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr10_+_47894572 0.05 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr1_+_151020175 0.05 ENST00000368926.5
C1orf56
chromosome 1 open reading frame 56
chr19_+_39936267 0.05 ENST00000359191.6
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr19_-_51538148 0.05 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr20_+_34359905 0.04 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
PHF20
PHD finger protein 20
chr19_+_53517174 0.04 ENST00000602168.1
ERVV-1
endogenous retrovirus group V, member 1
chr2_+_55459808 0.04 ENST00000404735.1
RPS27A
ribosomal protein S27a
chr1_+_172628154 0.04 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr8_-_20161466 0.04 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr19_+_39936186 0.04 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr2_+_216974020 0.04 ENST00000392132.2
ENST00000417391.1
XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr7_-_86595190 0.04 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr11_-_11374904 0.04 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr1_+_36396791 0.04 ENST00000246314.6
AGO3
argonaute RISC catalytic component 3
chr20_-_1472029 0.04 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr10_+_50507232 0.04 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr22_+_41487711 0.04 ENST00000263253.7
EP300
E1A binding protein p300
chr10_-_1071796 0.04 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr21_+_27011899 0.04 ENST00000425221.2
JAM2
junctional adhesion molecule 2
chr2_-_55459485 0.04 ENST00000451916.1
CLHC1
clathrin heavy chain linker domain containing 1
chr14_-_24911971 0.04 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr13_-_103719196 0.04 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_-_107204706 0.04 ENST00000393603.2
COG5
component of oligomeric golgi complex 5
chr7_+_137761199 0.04 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr16_+_27078219 0.03 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr6_+_160542821 0.03 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr14_-_23446900 0.03 ENST00000556731.1
AJUBA
ajuba LIM protein
chr19_+_1077393 0.03 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr10_+_71561704 0.03 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.2 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.2 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.3 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.5 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0002177 manchette(GO:0002177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004132 dCMP deaminase activity(GO:0004132)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators