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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX21_TBR1

Z-value: 0.70

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Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
TBX21
ENSG00000073861.2 T-box transcription factor 21
TBR1
ENSG00000136535.10 T-box brain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBR1hg19_v2_chr2_+_162272605_1622727530.019.8e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142315294 0.71 ENST00000464320.1
PLS1
plastin 1
chr1_-_153029980 0.59 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr7_+_107220660 0.50 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr1_-_153066998 0.46 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr1_-_156786634 0.39 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr2_+_228678550 0.36 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr15_-_80263506 0.36 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr7_-_127032741 0.35 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr11_+_93754513 0.32 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr1_+_35734616 0.32 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr16_+_69139467 0.31 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr12_+_65672702 0.30 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr1_-_44482979 0.29 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr12_-_89746264 0.28 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr15_+_44119159 0.28 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
WDR76
WD repeat domain 76
chr1_-_156786530 0.28 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr1_+_10057274 0.27 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr9_+_26956371 0.27 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr12_-_52685312 0.26 ENST00000327741.5
KRT81
keratin 81
chr11_+_64073699 0.24 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr17_-_76356148 0.24 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr19_-_7990991 0.23 ENST00000318978.4
CTXN1
cortexin 1
chr19_+_10381769 0.23 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr18_-_59561417 0.23 ENST00000591306.1
RNF152
ring finger protein 152
chr8_+_103876528 0.23 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr1_-_1009683 0.22 ENST00000453464.2
RNF223
ring finger protein 223
chr4_+_2626988 0.22 ENST00000509050.1
FAM193A
family with sequence similarity 193, member A
chrX_-_119693745 0.22 ENST00000371323.2
CUL4B
cullin 4B
chr5_+_150040403 0.22 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr5_+_158654712 0.22 ENST00000520323.1
CTB-11I22.2
CTB-11I22.2
chr14_+_95078714 0.21 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_+_177534653 0.21 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr8_-_99955042 0.21 ENST00000519420.1
STK3
serine/threonine kinase 3
chr13_-_30683005 0.20 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr3_-_61237050 0.20 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr3_+_142315225 0.19 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr4_+_154622652 0.19 ENST00000260010.6
TLR2
toll-like receptor 2
chr12_-_89746173 0.19 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr9_+_33750515 0.18 ENST00000361005.5
PRSS3
protease, serine, 3
chr8_-_99954788 0.18 ENST00000523601.1
STK3
serine/threonine kinase 3
chr9_+_26956474 0.18 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr1_-_6260896 0.17 ENST00000497965.1
RPL22
ribosomal protein L22
chr20_-_44516256 0.17 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr11_+_114271251 0.17 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr1_+_144989309 0.17 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr12_+_57854274 0.17 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr6_-_26108355 0.17 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr17_+_4046964 0.17 ENST00000573984.1
CYB5D2
cytochrome b5 domain containing 2
chr5_+_74807581 0.17 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr19_+_48949087 0.16 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr4_+_140222609 0.16 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chrX_+_105412290 0.16 ENST00000357175.2
ENST00000337685.2
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr18_+_55712915 0.16 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr14_+_32546145 0.16 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr5_+_74807886 0.16 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr14_+_21467414 0.16 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr2_-_157189180 0.15 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr14_+_77582905 0.15 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr16_+_53133070 0.15 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_+_155099927 0.15 ENST00000368407.3
EFNA1
ephrin-A1
chr4_+_74735102 0.15 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_+_56653064 0.15 ENST00000593100.1
ZNF444
zinc finger protein 444
chr1_-_205290865 0.15 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr14_-_62217779 0.15 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr1_-_108743471 0.15 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr7_+_76101379 0.14 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr16_+_50313426 0.14 ENST00000569265.1
ADCY7
adenylate cyclase 7
chr6_-_13487825 0.14 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr13_-_30160925 0.14 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr8_+_144766617 0.14 ENST00000454097.1
ENST00000534303.1
ENST00000529833.1
ENST00000530574.1
ENST00000442058.2
ENST00000358656.4
ENST00000526970.1
ENST00000532158.1
ZNF707
zinc finger protein 707
chr16_+_30386098 0.14 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_-_120497178 0.13 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr10_-_75226166 0.13 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr11_-_76155700 0.13 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr9_+_33750667 0.13 ENST00000457896.1
ENST00000342836.4
ENST00000429677.3
PRSS3
protease, serine, 3
chr5_+_137514403 0.13 ENST00000513276.1
KIF20A
kinesin family member 20A
chr12_+_66582919 0.13 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr22_-_38699003 0.13 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr19_+_1000418 0.13 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr3_-_197024394 0.13 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_102758210 0.12 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr11_-_615570 0.12 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr2_+_102758751 0.12 ENST00000442590.1
IL1R1
interleukin 1 receptor, type I
chr6_-_160166218 0.12 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr1_+_156105878 0.12 ENST00000508500.1
LMNA
lamin A/C
chr16_-_88717482 0.12 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr5_+_132009675 0.12 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr12_+_32112340 0.12 ENST00000540924.1
ENST00000312561.4
KIAA1551
KIAA1551
chr16_+_69140122 0.12 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr11_-_18956556 0.11 ENST00000302797.3
MRGPRX1
MAS-related GPR, member X1
chr1_-_44818599 0.11 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr11_+_114270752 0.11 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr19_-_35068562 0.11 ENST00000595013.1
SCGB1B2P
secretoglobin, family 1B, member 2, pseudogene
chr1_+_28586006 0.11 ENST00000253063.3
SESN2
sestrin 2
chr14_+_32546274 0.11 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr1_-_115124257 0.11 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr2_-_61697862 0.11 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr9_-_96717654 0.10 ENST00000253968.6
BARX1
BARX homeobox 1
chr16_-_88717423 0.10 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr10_+_4868460 0.10 ENST00000532248.1
ENST00000345253.5
ENST00000334019.4
AKR1E2
aldo-keto reductase family 1, member E2
chr17_-_38721711 0.10 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr19_+_38779778 0.10 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4
serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4
chrX_-_15872914 0.10 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_207630081 0.10 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr2_-_230933709 0.10 ENST00000436869.1
ENST00000295190.4
SLC16A14
solute carrier family 16, member 14
chrX_+_16804544 0.09 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr11_-_60010556 0.09 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr6_-_130536774 0.09 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr3_-_57678772 0.09 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr8_+_120220561 0.09 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr19_+_50529329 0.09 ENST00000599155.1
ZNF473
zinc finger protein 473
chr9_+_17135016 0.09 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr1_+_202172848 0.09 ENST00000255432.7
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr16_-_4395905 0.09 ENST00000571941.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr12_+_65672423 0.09 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3
methionine sulfoxide reductase B3
chr9_+_34329493 0.09 ENST00000379158.2
ENST00000346365.4
ENST00000379155.5
NUDT2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr19_+_3762703 0.09 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr4_+_48833070 0.09 ENST00000511662.1
ENST00000508996.1
ENST00000507210.1
ENST00000264312.7
ENST00000396448.2
ENST00000512236.1
ENST00000509164.1
ENST00000511102.1
ENST00000381473.3
OCIAD1
OCIA domain containing 1
chr17_+_26662679 0.09 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chrX_-_132549506 0.09 ENST00000370828.3
GPC4
glypican 4
chr20_+_58630972 0.09 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr19_-_50529193 0.09 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr19_-_36236292 0.09 ENST00000378975.3
ENST00000412391.2
ENST00000292879.5
U2AF1L4
U2 small nuclear RNA auxiliary factor 1-like 4
chr13_+_76378305 0.08 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr3_+_57741957 0.08 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr6_+_131894284 0.08 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr2_+_201994042 0.08 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_-_72619869 0.08 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr4_+_48833312 0.08 ENST00000508293.1
ENST00000513391.2
OCIAD1
OCIA domain containing 1
chr16_+_8715536 0.08 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr3_-_107777208 0.08 ENST00000398258.3
CD47
CD47 molecule
chr20_-_1165319 0.08 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr19_-_47226468 0.08 ENST00000600615.1
STRN4
striatin, calmodulin binding protein 4
chr2_-_113594279 0.08 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_+_19967014 0.08 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr20_+_2517253 0.08 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr5_+_133861339 0.08 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr11_-_95657231 0.08 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2
chr7_-_87849340 0.08 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr8_+_22428457 0.08 ENST00000517962.1
SORBS3
sorbin and SH3 domain containing 3
chr17_-_43502987 0.08 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr11_-_64052111 0.08 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD
BCL2-associated agonist of cell death
chr6_-_110500826 0.08 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr4_+_108746282 0.08 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr1_-_113247543 0.08 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr3_+_185000729 0.08 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr4_+_48833015 0.07 ENST00000509122.1
ENST00000509664.1
ENST00000505922.2
ENST00000514981.1
OCIAD1
OCIA domain containing 1
chr22_+_42196666 0.07 ENST00000402061.3
ENST00000255784.5
CCDC134
coiled-coil domain containing 134
chr6_-_97731019 0.07 ENST00000275053.4
MMS22L
MMS22-like, DNA repair protein
chr19_-_43702231 0.07 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr17_+_8191815 0.07 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr2_+_29033682 0.07 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr19_-_3500635 0.07 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr1_+_202995611 0.07 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr14_-_98444386 0.07 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr5_-_49737184 0.07 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr1_+_38022572 0.07 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chrX_-_19689106 0.07 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr2_-_152146385 0.07 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chrX_+_47077680 0.07 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr8_+_145218673 0.07 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr9_+_35829208 0.07 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr12_-_71148413 0.07 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr9_-_117853297 0.07 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr12_+_21525818 0.07 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr3_+_167453493 0.07 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr7_+_133261209 0.07 ENST00000545148.1
EXOC4
exocyst complex component 4
chr1_+_93544791 0.07 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr11_-_28129656 0.07 ENST00000263181.6
KIF18A
kinesin family member 18A
chr9_+_78505581 0.07 ENST00000376767.3
ENST00000376752.4
PCSK5
proprotein convertase subtilisin/kexin type 5
chr11_+_65687158 0.07 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr4_+_718896 0.07 ENST00000433814.1
PCGF3
polycomb group ring finger 3
chr19_-_39390212 0.07 ENST00000437828.1
SIRT2
sirtuin 2
chr2_+_162087577 0.07 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr15_-_43559055 0.07 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr11_-_82997013 0.06 ENST00000529073.1
ENST00000529611.1
CCDC90B
coiled-coil domain containing 90B
chr16_+_30212378 0.06 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr17_-_60005365 0.06 ENST00000444766.3
INTS2
integrator complex subunit 2
chr3_+_112709804 0.06 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr1_+_154975110 0.06 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr3_+_187896331 0.06 ENST00000392468.2
AC022498.1
Uncharacterized protein
chr9_+_134378289 0.06 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1
protein-O-mannosyltransferase 1
chr4_+_87857538 0.06 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr16_-_18911366 0.06 ENST00000565224.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr7_+_73106926 0.06 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr6_-_24646249 0.06 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319
KIAA0319
chr15_-_65903512 0.06 ENST00000567923.1
VWA9
von Willebrand factor A domain containing 9
chr10_+_135050908 0.06 ENST00000325980.9
VENTX
VENT homeobox
chrX_-_128788914 0.06 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr2_+_219246746 0.06 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr19_-_55580838 0.06 ENST00000396247.3
ENST00000586945.1
ENST00000587026.1
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr12_+_109490370 0.06 ENST00000257548.5
ENST00000536723.1
ENST00000536393.1
USP30
ubiquitin specific peptidase 30
chr19_-_44174330 0.06 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr17_+_46185111 0.06 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr19_-_55549624 0.06 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
GP6
glycoprotein VI (platelet)
chr3_+_124355944 0.06 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr20_+_30193083 0.06 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr1_-_114414316 0.06 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr15_+_89922345 0.06 ENST00000558982.1
LINC00925
long intergenic non-protein coding RNA 925
chr2_+_58134756 0.06 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:1903660 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.4 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0003068 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.0 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) natural killer cell tolerance induction(GO:0002519) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0002645 positive regulation of tolerance induction(GO:0002645)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.0 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.0 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.0 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines