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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX9

Z-value: 0.59

Motif logo

Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
ENSG00000125398.5 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg19_v2_chr17_+_70117153_70117174-0.226.7e-01Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_30934376 0.55 ENST00000562798.1
ENST00000471231.2
F-box and leucine-rich repeat protein 19
chr12_-_49581152 0.41 ENST00000550811.1
tubulin, alpha 1a
chr11_+_110001723 0.37 ENST00000528673.1
zinc finger CCCH-type containing 12C
chr12_+_27623565 0.36 ENST00000535986.1
single-pass membrane protein with coiled-coil domains 2
chr17_+_40119801 0.33 ENST00000585452.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_+_30687978 0.32 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr14_-_38036271 0.31 ENST00000556024.1
RP11-356O9.2
chr2_+_232573208 0.28 ENST00000409115.3
prothymosin, alpha
chr2_+_232573222 0.26 ENST00000341369.7
ENST00000409683.1
prothymosin, alpha
chr16_+_89989687 0.22 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr5_+_76012009 0.22 ENST00000505600.1
coagulation factor II (thrombin) receptor
chr7_+_129015671 0.21 ENST00000466993.1
adenosylhomocysteinase-like 2
chr17_-_49124230 0.20 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr6_-_11232891 0.20 ENST00000379433.5
ENST00000379446.5
neural precursor cell expressed, developmentally down-regulated 9
chr5_-_141338377 0.20 ENST00000510041.1
protocadherin 12
chr8_+_42196000 0.19 ENST00000518925.1
ENST00000538005.1
polymerase (DNA directed), beta
chr12_+_49621658 0.19 ENST00000541364.1
tubulin, alpha 1c
chr2_-_240322643 0.19 ENST00000345617.3
histone deacetylase 4
chr3_-_57583130 0.19 ENST00000303436.6
ADP-ribosylation factor 4
chr22_+_31090793 0.19 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
oxysterol binding protein 2
chr8_+_126442563 0.19 ENST00000311922.3
tribbles pseudokinase 1
chr10_+_97803151 0.19 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr7_+_129015484 0.18 ENST00000490911.1
adenosylhomocysteinase-like 2
chr6_+_29691198 0.18 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr12_-_49582978 0.17 ENST00000301071.7
tubulin, alpha 1a
chr8_+_24151553 0.17 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr11_+_60691924 0.17 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
transmembrane protein 132A
chr11_+_28724129 0.17 ENST00000513853.1
RP11-115J23.1
chr2_+_74212073 0.17 ENST00000441217.1
AC073046.25
chr19_+_13906250 0.17 ENST00000254323.2
zinc finger, SWIM-type containing 4
chr1_+_64239657 0.17 ENST00000371080.1
ENST00000371079.1
receptor tyrosine kinase-like orphan receptor 1
chr22_-_42739533 0.16 ENST00000515426.1
transcription factor 20 (AR1)
chr14_+_102276192 0.16 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr19_+_45504688 0.16 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr22_-_32022280 0.16 ENST00000442379.1
phosphatidylserine decarboxylase
chr1_+_144339738 0.16 ENST00000538264.1
Protein LOC642441
chr7_+_26191809 0.16 ENST00000056233.3
nuclear factor, erythroid 2-like 3
chr7_+_77167343 0.16 ENST00000433369.2
ENST00000415482.2
protein tyrosine phosphatase, non-receptor type 12
chr5_-_43313574 0.16 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_-_125365435 0.16 ENST00000524435.1
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_77751931 0.16 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr12_+_49761147 0.16 ENST00000549298.1
spermatogenesis associated, serine-rich 2
chr12_-_49582593 0.15 ENST00000295766.5
tubulin, alpha 1a
chr5_-_141338627 0.15 ENST00000231484.3
protocadherin 12
chr22_+_38054721 0.15 ENST00000215904.6
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr17_+_16945820 0.15 ENST00000577514.1
myosin phosphatase Rho interacting protein
chr4_+_24661479 0.14 ENST00000569621.1
RP11-496D24.2
chr15_-_59041954 0.14 ENST00000439637.1
ENST00000558004.1
ADAM metallopeptidase domain 10
chr6_-_75915757 0.14 ENST00000322507.8
collagen, type XII, alpha 1
chr5_-_16936340 0.14 ENST00000507288.1
ENST00000513610.1
myosin X
chr1_-_200992827 0.14 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr6_-_107436473 0.13 ENST00000369042.1
BEN domain containing 3
chr20_+_34679725 0.13 ENST00000432589.1
erythrocyte membrane protein band 4.1-like 1
chr7_-_131241361 0.13 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr17_+_46970134 0.13 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr5_+_172068232 0.13 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
neuralized E3 ubiquitin protein ligase 1B
chr7_+_18535321 0.13 ENST00000413380.1
ENST00000430454.1
histone deacetylase 9
chr6_-_27100529 0.13 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr3_-_57583052 0.13 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr5_-_65018834 0.13 ENST00000506816.1
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_-_204436344 0.13 ENST00000367184.2
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr7_+_28452130 0.13 ENST00000357727.2
cAMP responsive element binding protein 5
chr10_+_6244829 0.12 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_156119466 0.12 ENST00000414683.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_+_175204865 0.12 ENST00000505124.1
centrosomal protein 44kDa
chr20_-_17662705 0.12 ENST00000455029.2
ribosome binding protein 1
chr8_+_24151620 0.12 ENST00000437154.2
ADAM metallopeptidase domain 28
chrX_+_78003204 0.12 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr11_-_8190534 0.12 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3 acetylcholine receptor chaperone
chr12_-_49582837 0.12 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
tubulin, alpha 1a
chr16_-_838329 0.12 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RNA pseudouridylate synthase domain containing 1
chrX_+_107288280 0.12 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr11_-_76155700 0.12 ENST00000572035.1
RP11-111M22.3
chr2_-_206950996 0.11 ENST00000414320.1
INO80 complex subunit D
chr3_+_88108381 0.11 ENST00000473136.1
Uncharacterized protein
chr1_-_153643442 0.11 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr15_+_89164560 0.11 ENST00000379231.3
ENST00000559528.1
apoptosis enhancing nuclease
chr22_-_30722912 0.11 ENST00000215790.7
TBC1 domain family, member 10A
chr7_+_155090271 0.11 ENST00000476756.1
insulin induced gene 1
chr4_-_40516560 0.11 ENST00000513473.1
RNA binding motif protein 47
chr6_-_139613269 0.11 ENST00000358430.3
taxilin beta
chr14_-_71276211 0.11 ENST00000381250.4
ENST00000555993.2
mitogen-activated protein kinase kinase kinase 9
chr5_-_64777685 0.11 ENST00000536360.1
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr17_-_74722672 0.11 ENST00000397625.4
ENST00000445478.2
jumonji domain containing 6
chr5_-_146435572 0.11 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr6_+_29691056 0.11 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr17_+_74723031 0.11 ENST00000586200.1
methyltransferase like 23
chr3_+_111718173 0.11 ENST00000494932.1
transgelin 3
chr8_+_42195972 0.11 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
polymerase (DNA directed), beta
chr1_-_198906528 0.11 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr6_+_21666633 0.11 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr10_+_71812577 0.11 ENST00000455786.1
H2A histone family, member Y2
chr17_-_14683517 0.11 ENST00000379640.1
AC005863.1
chr5_-_146833222 0.11 ENST00000534907.1
dihydropyrimidinase-like 3
chr6_+_41040678 0.11 ENST00000341376.6
ENST00000353205.5
nuclear transcription factor Y, alpha
chr1_+_161195835 0.11 ENST00000545897.1
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr11_+_126225529 0.10 ENST00000227495.6
ENST00000444328.2
ENST00000356132.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr7_+_99699280 0.10 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr8_-_49533521 0.10 ENST00000523038.1
RP11-567J20.1
chr12_-_95611149 0.10 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FYVE, RhoGEF and PH domain containing 6
chr5_-_146435694 0.10 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr6_-_108278456 0.10 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr11_+_128563652 0.10 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr19_+_10765614 0.10 ENST00000589283.1
interleukin enhancer binding factor 3, 90kDa
chr2_+_208576259 0.10 ENST00000392209.3
cyclin Y-like 1
chr12_+_49761273 0.10 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
spermatogenesis associated, serine-rich 2
chr9_-_35111570 0.10 ENST00000378561.1
ENST00000603301.1
family with sequence similarity 214, member B
chr22_-_22292934 0.09 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr8_-_38326139 0.09 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
fibroblast growth factor receptor 1
chr12_+_69979210 0.09 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr11_-_92930556 0.09 ENST00000529184.1
solute carrier family 36 (proton/amino acid symporter), member 4
chr5_+_69321074 0.09 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
small EDRK-rich factor 1B (centromeric)
chr8_-_66753682 0.09 ENST00000396642.3
phosphodiesterase 7A
chr6_-_134861089 0.09 ENST00000606039.1
RP11-557H15.4
chr7_-_27205136 0.09 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr7_-_107968999 0.09 ENST00000456431.1
neuronal cell adhesion molecule
chr6_+_22146851 0.09 ENST00000606197.1
cancer susceptibility candidate 15 (non-protein coding)
chr15_+_57211318 0.09 ENST00000557947.1
transcription factor 12
chr19_-_8408139 0.09 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KN motif and ankyrin repeat domains 3
chrX_+_9433289 0.09 ENST00000422314.1
transducin (beta)-like 1X-linked
chr7_+_77167376 0.09 ENST00000435495.2
protein tyrosine phosphatase, non-receptor type 12
chr12_+_69979113 0.09 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr4_-_184241927 0.09 ENST00000323319.5
claudin 22
chr18_+_3450161 0.09 ENST00000551402.1
ENST00000577543.1
TGFB-induced factor homeobox 1
chr7_+_18535346 0.09 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr20_+_48884002 0.09 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr19_+_10765003 0.09 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr12_+_69979446 0.09 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)
chr7_+_76751926 0.09 ENST00000285871.4
ENST00000431197.1
coiled-coil domain containing 146
chr17_+_9066252 0.09 ENST00000436734.1
netrin 1
chr19_+_10765699 0.09 ENST00000590009.1
interleukin enhancer binding factor 3, 90kDa
chr19_+_54641444 0.08 ENST00000221232.5
ENST00000358389.3
CCR4-NOT transcription complex, subunit 3
chr10_+_91461413 0.08 ENST00000447580.1
kinesin family member 20B
chr6_+_89790459 0.08 ENST00000369472.1
proline-rich nuclear receptor coactivator 1
chr9_+_35538616 0.08 ENST00000455600.1
RUN and SH3 domain containing 2
chr1_-_32801825 0.08 ENST00000329421.7
MARCKS-like 1
chr11_-_65640071 0.08 ENST00000526624.1
EGF containing fibulin-like extracellular matrix protein 2
chr7_-_150924121 0.08 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ATP-binding cassette, sub-family F (GCN20), member 2
chr14_-_21516590 0.08 ENST00000555026.1
NDRG family member 2
chr1_-_204463829 0.08 ENST00000429009.1
ENST00000415899.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_-_205912577 0.08 ENST00000367135.3
ENST00000367134.2
solute carrier family 26 (anion exchanger), member 9
chr19_-_10491130 0.08 ENST00000530829.1
ENST00000529370.1
tyrosine kinase 2
chrX_-_130037162 0.08 ENST00000432489.1
ecto-NOX disulfide-thiol exchanger 2
chr15_+_41136369 0.08 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr19_-_19739321 0.08 ENST00000588461.1
lysophosphatidic acid receptor 2
chr5_+_40841410 0.08 ENST00000381677.3
caspase recruitment domain family, member 6
chr16_-_75590114 0.08 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
transmembrane protein 231
chr2_-_70475730 0.08 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr1_+_228337553 0.08 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr17_+_18128896 0.08 ENST00000316843.4
lethal giant larvae homolog 1 (Drosophila)
chr9_-_35828576 0.08 ENST00000377984.2
ENST00000423537.2
ENST00000472182.1
family with sequence similarity 221, member B
chr3_-_122283424 0.08 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr2_-_1748214 0.08 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
peroxidasin homolog (Drosophila)
chr9_-_35111420 0.07 ENST00000378557.1
family with sequence similarity 214, member B
chr15_+_76629064 0.07 ENST00000290759.4
ISL LIM homeobox 2
chr5_-_146435501 0.07 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr1_+_200993071 0.07 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
chr17_-_37764128 0.07 ENST00000302584.4
neuronal differentiation 2
chr15_+_41136734 0.07 ENST00000568580.1
serine peptidase inhibitor, Kunitz type 1
chr1_-_21503337 0.07 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr11_+_63953587 0.07 ENST00000305218.4
ENST00000538945.1
stress-induced-phosphoprotein 1
chr22_-_30722866 0.07 ENST00000403477.3
TBC1 domain family, member 10A
chr15_+_74911430 0.07 ENST00000562670.1
ENST00000564096.1
CDC-like kinase 3
chr6_-_128841503 0.07 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr15_+_31619013 0.07 ENST00000307145.3
Kruppel-like factor 13
chr7_-_5463175 0.07 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr19_+_45394477 0.07 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr11_-_76155618 0.07 ENST00000530759.1
RP11-111M22.3
chr17_+_7761301 0.07 ENST00000332439.4
ENST00000570446.1
cytochrome b5 domain containing 1
chr3_-_149510553 0.07 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr11_+_63953691 0.07 ENST00000543847.1
stress-induced-phosphoprotein 1
chr8_-_38326119 0.07 ENST00000356207.5
ENST00000326324.6
fibroblast growth factor receptor 1
chr19_-_7694417 0.07 ENST00000358368.4
ENST00000534844.1
XPA binding protein 2
chr7_-_111846435 0.07 ENST00000437633.1
ENST00000428084.1
dedicator of cytokinesis 4
chr11_-_33183048 0.07 ENST00000438862.2
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr17_-_76713100 0.07 ENST00000585509.1
cytohesin 1
chr2_+_74425689 0.07 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr20_-_17662878 0.07 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
ribosome binding protein 1
chr20_-_45984401 0.07 ENST00000311275.7
zinc finger, MYND-type containing 8
chr19_+_34887220 0.07 ENST00000592740.1
Uncharacterized protein
chr17_-_74722536 0.07 ENST00000585429.1
jumonji domain containing 6
chr22_+_21987005 0.07 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr16_-_25026641 0.07 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
Rho GTPase activating protein 17
chr2_+_54683419 0.06 ENST00000356805.4
spectrin, beta, non-erythrocytic 1
chr5_-_60240858 0.06 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
excision repair cross-complementing rodent repair deficiency, complementation group 8
chrX_-_19817869 0.06 ENST00000379698.4
SH3-domain kinase binding protein 1
chr6_+_53976235 0.06 ENST00000502396.1
ENST00000358276.5
muscular LMNA-interacting protein
chr5_-_131826457 0.06 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr1_-_113247543 0.06 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr5_-_157079428 0.06 ENST00000265007.6
SRY (sex determining region Y)-box 30
chr9_-_73483926 0.06 ENST00000396283.1
ENST00000361823.5
transient receptor potential cation channel, subfamily M, member 3
chr3_+_14444063 0.06 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_+_6640046 0.06 ENST00000319084.5
ENST00000435905.1
zinc finger and BTB domain containing 48
chr11_-_67141090 0.06 ENST00000312438.7
cardiotrophin-like cytokine factor 1
chr3_+_45635661 0.06 ENST00000440097.1
LIM domains containing 1
chrX_+_68048803 0.06 ENST00000204961.4
ephrin-B1
chr3_-_48700310 0.06 ENST00000164024.4
ENST00000544264.1
cadherin, EGF LAG seven-pass G-type receptor 3
chr17_-_4871085 0.06 ENST00000575142.1
ENST00000206020.3
sperm associated antigen 7
chr19_+_58790314 0.06 ENST00000196548.5
ENST00000608843.1
Zinc finger protein 8
zinc finger protein 8
chr1_-_243418344 0.06 ENST00000366542.1
centrosomal protein 170kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.2 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.0 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0032618 interleukin-15 production(GO:0032618)
0.0 0.1 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.0 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.0 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) negative regulation of cytolysis(GO:0045918) regulation of cytolysis in other organism(GO:0051710)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.0 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0098519 phosphoserine phosphatase activity(GO:0004647) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1