Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for SOX5
Z-value: 0.93
Motif logo
Transcription factors associated with SOX5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX5 | hg19_v2_chr12_-_24103954_24103972 | -0.04 | 9.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_166702601 Show fit | 0.43 |
ENST00000428888.1
|
AC009495.4 |
|
| chr17_+_33448593 Show fit | 0.38 |
ENST00000158009.5
|
fibronectin type III domain containing 8 |
|
| chr14_-_92413727 Show fit | 0.36 |
ENST00000267620.10
|
fibulin 5 |
|
| chr2_-_164592497 Show fit | 0.34 |
ENST00000333129.3
ENST00000409634.1 |
fidgetin |
|
| chr3_+_112930306 Show fit | 0.31 |
ENST00000495514.1
|
BOC cell adhesion associated, oncogene regulated |
|
| chr17_+_67498396 Show fit | 0.28 |
ENST00000588110.1
|
mitogen-activated protein kinase kinase 6 |
|
| chr3_+_25469802 Show fit | 0.27 |
ENST00000330688.4
|
retinoic acid receptor, beta |
|
| chr3_+_181429704 Show fit | 0.27 |
ENST00000431565.2
ENST00000325404.1 |
SRY (sex determining region Y)-box 2 |
|
| chr19_+_36132631 Show fit | 0.26 |
ENST00000379026.2
ENST00000379023.4 ENST00000402764.2 ENST00000479824.1 |
ets variant 2 |
|
| chr5_-_146461027 Show fit | 0.25 |
ENST00000394410.2
ENST00000508267.1 ENST00000504198.1 |
protein phosphatase 2, regulatory subunit B, beta |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.5 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 0.5 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 0.4 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 0.3 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 0.3 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.1 | 0.3 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.3 | GO:0030421 | defecation(GO:0030421) |
| 0.0 | 0.3 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.0 | 0.3 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.0 | 0.3 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.0 | 0.2 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.1 | GO:0000806 | Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134) |
| 0.0 | 0.1 | GO:0031673 | H zone(GO:0031673) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.0 | 0.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.3 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.3 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.0 | 0.2 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.0 | 0.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.2 | GO:0035005 | lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.4 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |