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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX5

Z-value: 0.93

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
SOX5
ENSG00000134532.11 SRY-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX5hg19_v2_chr12_-_24103954_24103972-0.049.4e-01Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_166702601 0.43 ENST00000428888.1
AC009495.4
AC009495.4
chr17_+_33448593 0.38 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr14_-_92413727 0.36 ENST00000267620.10
FBLN5
fibulin 5
chr2_-_164592497 0.34 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr3_+_112930306 0.31 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr17_+_67498396 0.28 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_25469802 0.27 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr3_+_181429704 0.27 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr19_+_36132631 0.26 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr5_-_146461027 0.25 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr2_-_25451065 0.24 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr4_+_165675197 0.24 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr8_-_72274467 0.24 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr3_+_25469724 0.24 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr7_+_116451100 0.23 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr9_-_98268883 0.23 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chr7_-_83824449 0.23 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_219615984 0.21 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr6_-_134861089 0.21 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr1_-_167883327 0.21 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr1_-_40367668 0.20 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_+_30814707 0.20 ENST00000584792.1
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_7698599 0.20 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr3_+_89156799 0.19 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr6_+_122720681 0.19 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr9_-_115249484 0.19 ENST00000457681.1
C9orf147
chromosome 9 open reading frame 147
chr1_-_204463829 0.19 ENST00000429009.1
ENST00000415899.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr9_-_72287191 0.18 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr2_-_70475586 0.18 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr3_-_123339418 0.18 ENST00000583087.1
MYLK
myosin light chain kinase
chr21_+_35553045 0.18 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chrX_-_106959631 0.18 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr15_+_49715449 0.18 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr14_-_92414294 0.18 ENST00000554468.1
FBLN5
fibulin 5
chr20_-_52612468 0.17 ENST00000422805.1
BCAS1
breast carcinoma amplified sequence 1
chr4_+_95916947 0.17 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr4_+_11627248 0.17 ENST00000510095.1
RP11-281P23.2
RP11-281P23.2
chr11_+_46402482 0.17 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr17_-_39459103 0.16 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr1_-_243349684 0.16 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr1_+_205682497 0.16 ENST00000598338.1
AC119673.1
AC119673.1
chr12_-_109797249 0.16 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr8_-_72274355 0.15 ENST00000388741.2
EYA1
eyes absent homolog 1 (Drosophila)
chrX_-_50557302 0.15 ENST00000289292.7
SHROOM4
shroom family member 4
chr2_-_192711968 0.14 ENST00000304141.4
SDPR
serum deprivation response
chr2_-_188312971 0.14 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr12_-_96793142 0.14 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr15_-_34610962 0.14 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr7_-_11871815 0.13 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr1_-_40367530 0.13 ENST00000372816.2
ENST00000372815.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr10_+_99079008 0.13 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr4_+_165675269 0.13 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chrX_-_117107542 0.13 ENST00000371878.1
KLHL13
kelch-like family member 13
chr12_+_498500 0.13 ENST00000540180.1
ENST00000422000.1
ENST00000535052.1
CCDC77
coiled-coil domain containing 77
chr20_-_3762087 0.13 ENST00000379756.3
SPEF1
sperm flagellar 1
chr1_+_33722080 0.13 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr17_+_1666108 0.13 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_+_91416092 0.13 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr15_+_84115868 0.13 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr13_+_110958124 0.12 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr15_+_49715293 0.12 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr5_+_67588391 0.12 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_+_53443963 0.12 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_155537771 0.12 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr15_+_90319557 0.12 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr3_-_123339343 0.12 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_+_53443680 0.12 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr14_-_73360796 0.12 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr1_-_12677714 0.12 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chrX_+_9880412 0.12 ENST00000418909.2
SHROOM2
shroom family member 2
chr10_-_116444371 0.12 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr4_+_110749143 0.11 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr2_+_47454054 0.11 ENST00000426892.1
AC106869.2
AC106869.2
chr19_+_18794470 0.11 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chrX_-_50557014 0.11 ENST00000376020.2
SHROOM4
shroom family member 4
chr6_-_79944336 0.11 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr20_-_61002584 0.11 ENST00000252998.1
RBBP8NL
RBBP8 N-terminal like
chr10_-_14614311 0.11 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr1_-_53018654 0.11 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr12_-_111926342 0.11 ENST00000389154.3
ATXN2
ataxin 2
chr1_+_164528866 0.11 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_25657444 0.11 ENST00000504570.1
ENST00000382051.3
SLC34A2
solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr1_-_50889155 0.10 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr11_-_82708435 0.10 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr10_-_14614122 0.10 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr14_-_92414055 0.10 ENST00000342058.4
FBLN5
fibulin 5
chr6_-_32557610 0.10 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr7_+_111846741 0.10 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
ZNF277
zinc finger protein 277
chr14_+_61654271 0.10 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr2_+_30569506 0.10 ENST00000421976.2
AC109642.1
AC109642.1
chr10_-_14613968 0.10 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr9_+_137218362 0.10 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr9_-_15510989 0.10 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chrX_+_24483338 0.10 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chr12_-_12674032 0.10 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr9_-_134145880 0.09 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr13_+_22245522 0.09 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr3_+_89156674 0.09 ENST00000336596.2
EPHA3
EPH receptor A3
chr17_-_47786375 0.09 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr6_-_56716686 0.09 ENST00000520645.1
DST
dystonin
chr11_-_72852958 0.09 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr4_-_184241927 0.09 ENST00000323319.5
CLDN22
claudin 22
chr12_-_122985067 0.09 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr1_+_164529004 0.09 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr18_+_3451646 0.09 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr12_+_50479109 0.09 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr18_+_21594585 0.09 ENST00000317571.3
TTC39C
tetratricopeptide repeat domain 39C
chr11_+_46402583 0.09 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr9_-_14314518 0.08 ENST00000397581.2
NFIB
nuclear factor I/B
chr8_-_72274095 0.08 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr9_-_126030817 0.08 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP
spermatid perinuclear RNA binding protein
chr20_-_52612705 0.08 ENST00000434986.2
BCAS1
breast carcinoma amplified sequence 1
chr1_-_156217829 0.08 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6
progestin and adipoQ receptor family member VI
chr3_+_171561127 0.08 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr10_-_99094458 0.08 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr4_+_39408470 0.08 ENST00000257408.4
KLB
klotho beta
chr5_+_140235469 0.08 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr18_+_3451584 0.08 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr9_-_123476612 0.08 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr12_+_9066472 0.08 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chrX_-_117107680 0.08 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr9_-_14314566 0.08 ENST00000397579.2
NFIB
nuclear factor I/B
chr6_+_126070726 0.08 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr8_-_57123815 0.08 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr10_-_14614095 0.08 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr7_-_32931623 0.07 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chrX_-_112084043 0.07 ENST00000304758.1
AMOT
angiomotin
chr19_+_31658405 0.07 ENST00000589511.1
CTC-439O9.3
CTC-439O9.3
chr3_-_11685345 0.07 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr12_-_121973974 0.07 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine (K)-specific demethylase 2B
chr11_-_79151695 0.07 ENST00000278550.7
TENM4
teneurin transmembrane protein 4
chr14_+_37126765 0.07 ENST00000402703.2
PAX9
paired box 9
chr12_+_50479101 0.07 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr9_-_123476719 0.07 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr5_+_138678131 0.07 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr4_-_186732048 0.07 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr21_-_39870339 0.07 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr14_-_69619823 0.07 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr11_+_46402744 0.07 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr6_-_13290684 0.07 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr1_+_147013182 0.07 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr1_-_156217822 0.07 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chr10_-_62332357 0.07 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_-_53177984 0.06 ENST00000543082.1
TCF4
transcription factor 4
chr2_-_230787879 0.06 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr4_+_170581213 0.06 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr16_+_86612112 0.06 ENST00000320241.3
FOXL1
forkhead box L1
chr9_-_92051354 0.06 ENST00000418828.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr4_-_186732892 0.06 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr9_+_129097479 0.06 ENST00000402437.2
MVB12B
multivesicular body subunit 12B
chr1_-_243418650 0.06 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr11_+_19799327 0.06 ENST00000540292.1
NAV2
neuron navigator 2
chr18_-_52989217 0.06 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_102323740 0.06 ENST00000398136.2
TMEM123
transmembrane protein 123
chr1_-_176176114 0.06 ENST00000308769.8
RFWD2
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
chr18_+_20494078 0.06 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr12_+_32654965 0.06 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr15_+_57211318 0.05 ENST00000557947.1
TCF12
transcription factor 12
chr10_+_63661053 0.05 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr14_-_22005018 0.05 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr1_-_156217875 0.05 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr10_+_121578211 0.05 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr15_-_52944231 0.05 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr1_-_11751529 0.05 ENST00000376672.1
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr12_-_122985494 0.05 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr6_+_43027595 0.05 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
KLC4
kinesin light chain 4
chr12_-_92536433 0.05 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr22_-_36236265 0.05 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_-_18466026 0.05 ENST00000417717.2
SATB1
SATB homeobox 1
chr4_-_87281196 0.05 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr1_+_61547405 0.05 ENST00000371189.4
NFIA
nuclear factor I/A
chr9_+_71394945 0.05 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr3_-_141747439 0.05 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_62149433 0.05 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_29241027 0.05 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_-_70475701 0.05 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr21_-_40720995 0.05 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr13_+_103459704 0.05 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr5_+_173316341 0.05 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr9_+_118916082 0.05 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_-_19988462 0.05 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr11_+_19798964 0.05 ENST00000527559.2
NAV2
neuron navigator 2
chrX_+_15525426 0.05 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr18_-_52989525 0.05 ENST00000457482.3
TCF4
transcription factor 4
chr3_+_120315160 0.05 ENST00000485064.1
ENST00000492739.1
NDUFB4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr6_+_37137939 0.05 ENST00000373509.5
PIM1
pim-1 oncogene
chr1_-_11751665 0.04 ENST00000376667.3
ENST00000235310.3
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr17_+_67498295 0.04 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_154797428 0.04 ENST00000460393.1
MME
membrane metallo-endopeptidase
chr12_+_498545 0.04 ENST00000543504.1
CCDC77
coiled-coil domain containing 77
chr14_-_69619689 0.04 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr14_-_69619291 0.04 ENST00000554215.1
ENST00000556847.1
DCAF5
DDB1 and CUL4 associated factor 5
chr12_-_99288536 0.04 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_69215467 0.04 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr18_+_21594384 0.04 ENST00000584250.1
TTC39C
tetratricopeptide repeat domain 39C
chr16_+_20911174 0.04 ENST00000568663.1
LYRM1
LYR motif containing 1
chr2_+_203499901 0.04 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr11_-_82708519 0.04 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr9_-_124989804 0.04 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr12_+_56360550 0.04 ENST00000266970.4
CDK2
cyclin-dependent kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.2 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.3 GO:0030421 defecation(GO:0030421)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection