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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX13_SOX12

Z-value: 1.07

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Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
ENSG00000143842.10 SRY-box transcription factor 13
ENSG00000177732.6 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg19_v2_chr20_+_306177_3062110.236.7e-01Click!
SOX13hg19_v2_chr1_+_204042723_204042784-0.019.8e-01Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_136070614 0.99 ENST00000502421.1
CTB-1I21.1
chr14_+_39703112 0.87 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr19_+_21106081 0.85 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr12_-_10573149 0.82 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
killer cell lectin-like receptor subfamily C, member 3
chr4_-_74864386 0.82 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr11_-_85393886 0.76 ENST00000534224.1
CREB/ATF bZIP transcription factor
chr11_-_8190534 0.70 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3 acetylcholine receptor chaperone
chr6_-_133055815 0.63 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr14_-_38036271 0.57 ENST00000556024.1
RP11-356O9.2
chr12_-_49581152 0.56 ENST00000550811.1
tubulin, alpha 1a
chr15_-_80263506 0.55 ENST00000335661.6
BCL2-related protein A1
chr17_-_57229155 0.54 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chrX_+_107288280 0.53 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr1_-_153013588 0.53 ENST00000360379.3
small proline-rich protein 2D
chr12_+_11081828 0.50 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr1_+_153003671 0.48 ENST00000307098.4
small proline-rich protein 1B
chr11_-_18258342 0.47 ENST00000278222.4
serum amyloid A4, constitutive
chr17_-_38859996 0.45 ENST00000264651.2
keratin 24
chr1_-_153363452 0.45 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr1_-_152539248 0.44 ENST00000368789.1
late cornified envelope 3E
chr1_-_153433120 0.44 ENST00000368723.3
S100 calcium binding protein A7
chr2_+_132479948 0.42 ENST00000355171.4
chromosome 2 open reading frame 27A
chr20_-_52612705 0.42 ENST00000434986.2
breast carcinoma amplified sequence 1
chr8_+_24151620 0.40 ENST00000437154.2
ADAM metallopeptidase domain 28
chr6_-_133055896 0.40 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr20_-_52612468 0.40 ENST00000422805.1
breast carcinoma amplified sequence 1
chr12_-_10588539 0.40 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr3_+_98699880 0.37 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr19_-_21512144 0.36 ENST00000602023.1
zinc finger protein 708
chr20_-_5426380 0.36 ENST00000609252.1
ENST00000422352.1
long intergenic non-protein coding RNA 658
chr14_+_94577074 0.36 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr13_-_38172863 0.35 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr12_+_27623565 0.34 ENST00000535986.1
single-pass membrane protein with coiled-coil domains 2
chr5_+_147582348 0.33 ENST00000514389.1
serine peptidase inhibitor, Kazal type 6
chr10_+_69865866 0.33 ENST00000354393.2
myopalladin
chr19_-_23433144 0.33 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
zinc finger protein 724, pseudogene
chr2_-_25100893 0.33 ENST00000433852.1
adenylate cyclase 3
chr6_+_12290586 0.33 ENST00000379375.5
endothelin 1
chr4_-_112993808 0.33 ENST00000511219.1
RP11-269F21.3
chr3_-_178976996 0.33 ENST00000485523.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr12_-_11036844 0.32 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr8_-_54752406 0.32 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr6_-_134861089 0.32 ENST00000606039.1
RP11-557H15.4
chr6_+_76599809 0.31 ENST00000430435.1
myosin VI
chr18_+_74240610 0.31 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr19_-_21512202 0.31 ENST00000356929.3
zinc finger protein 708
chr1_+_10057274 0.31 ENST00000294435.7
retinol binding protein 7, cellular
chr15_-_41166414 0.31 ENST00000220507.4
ras homolog family member V
chr17_-_57158523 0.30 ENST00000581468.1
tripartite motif containing 37
chr2_+_102927962 0.30 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr1_-_153029980 0.30 ENST00000392653.2
small proline-rich protein 2A
chr4_+_154622652 0.30 ENST00000260010.6
toll-like receptor 2
chr3_+_177534653 0.30 ENST00000436078.1
RP11-91K9.1
chr7_-_64023441 0.30 ENST00000309683.6
zinc finger protein 680
chr4_+_78829479 0.30 ENST00000504901.1
mitochondrial ribosomal protein L1
chr8_+_24151553 0.29 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr12_-_11175219 0.29 ENST00000390673.2
taste receptor, type 2, member 19
chr7_+_111846741 0.29 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
zinc finger protein 277
chr4_+_74301880 0.28 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr6_-_139613269 0.28 ENST00000358430.3
taxilin beta
chr11_-_62609281 0.27 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr2_+_143635067 0.27 ENST00000264170.4
kynureninase
chr12_+_28605426 0.27 ENST00000542801.1
coiled-coil domain containing 91
chr16_+_30709530 0.26 ENST00000411466.2
Snf2-related CREBBP activator protein
chr8_-_71157595 0.26 ENST00000519724.1
nuclear receptor coactivator 2
chr2_-_238499337 0.26 ENST00000411462.1
ENST00000409822.1
RAB17, member RAS oncogene family
chr4_+_11470867 0.26 ENST00000515343.1
RP11-281P23.1
chr4_+_110749143 0.25 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr2_-_165630264 0.25 ENST00000452626.1
cordon-bleu WH2 repeat protein-like 1
chr18_+_68002675 0.25 ENST00000584919.1
Uncharacterized protein
chr4_-_57547454 0.25 ENST00000556376.2
HOP homeobox
chr4_+_70916119 0.24 ENST00000246896.3
ENST00000511674.1
histatin 1
chr7_-_41742697 0.24 ENST00000242208.4
inhibin, beta A
chr4_+_95128996 0.24 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_-_66317967 0.24 ENST00000601398.1
Uncharacterized protein
chr3_+_177545563 0.24 ENST00000434309.1
RP11-91K9.1
chr1_-_116383322 0.23 ENST00000429731.1
nescient helix loop helix 2
chr8_+_94752349 0.23 ENST00000391680.1
RBM12B antisense RNA 1
chr10_+_94594351 0.23 ENST00000371552.4
exocyst complex component 6
chr7_-_7575477 0.22 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr12_+_113354341 0.22 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_44809027 0.22 ENST00000507110.1
mitochondrial ribosomal protein S30
chr12_+_60058458 0.22 ENST00000548610.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_179318295 0.22 ENST00000442710.1
deafness, autosomal recessive 59
chr11_-_327537 0.22 ENST00000602735.1
interferon induced transmembrane protein 3
chr10_+_118187379 0.21 ENST00000369230.3
pancreatic lipase-related protein 3
chr7_+_871559 0.21 ENST00000421580.1
Sad1 and UNC84 domain containing 1
chr12_+_26205496 0.21 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr12_+_78224667 0.21 ENST00000549464.1
neuron navigator 3
chr3_-_32544900 0.20 ENST00000205636.3
CKLF-like MARVEL transmembrane domain containing 6
chr4_+_53728457 0.20 ENST00000248706.3
RAS-like, family 11, member B
chr8_+_105602961 0.20 ENST00000521923.1
Uncharacterized protein
chr21_+_43619796 0.20 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr12_-_76461249 0.20 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr6_-_108278456 0.20 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr21_+_17214724 0.20 ENST00000449491.1
ubiquitin specific peptidase 25
chr7_+_7196565 0.20 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr4_+_187148556 0.20 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
kallikrein B, plasma (Fletcher factor) 1
chr6_-_26285737 0.20 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr3_+_119814070 0.20 ENST00000469070.1
RP11-18H7.1
chr12_-_68835991 0.20 ENST00000546086.1
RP11-81H14.2
chr7_-_35013217 0.20 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr13_-_49987885 0.19 ENST00000409082.1
calcium binding protein 39-like
chr4_+_95128748 0.19 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_+_64126503 0.19 ENST00000360117.3
zinc finger protein 107
chr6_+_26217159 0.19 ENST00000303910.2
histone cluster 1, H2ae
chr3_-_57678772 0.19 ENST00000311128.5
DENN/MADD domain containing 6A
chr19_-_22018966 0.19 ENST00000599906.1
ENST00000354959.4
zinc finger protein 43
chr7_-_112635675 0.19 ENST00000447785.1
ENST00000451962.1
AC018464.3
chr12_-_10601963 0.19 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chr5_+_110073853 0.19 ENST00000513807.1
ENST00000509442.2
solute carrier family 25, member 46
chr8_+_40010989 0.19 ENST00000315792.3
chromosome 8 open reading frame 4
chr14_+_22600515 0.18 ENST00000390456.3
T cell receptor alpha variable 8-7 (non-functional)
chr16_+_89160217 0.18 ENST00000317447.4
ENST00000537290.1
acyl-CoA synthetase family member 3
chr11_-_85430088 0.18 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr8_-_141774467 0.18 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr1_+_212475148 0.18 ENST00000537030.3
protein phosphatase 2, regulatory subunit B', alpha
chr17_-_71223839 0.18 ENST00000579872.1
ENST00000580032.1
family with sequence similarity 104, member A
chr3_-_135916073 0.18 ENST00000481989.1
male-specific lethal 2 homolog (Drosophila)
chrX_+_108780347 0.18 ENST00000372103.1
nuclear transport factor 2-like export factor 2
chr2_+_162101247 0.18 ENST00000439050.1
ENST00000436506.1
AC009299.3
chr14_+_39944025 0.18 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr17_+_61151306 0.17 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr18_-_59415987 0.17 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
chr21_+_35553045 0.17 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
long intergenic non-protein coding RNA 310
chr8_-_42358742 0.17 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr19_+_41882466 0.17 ENST00000436170.2
transmembrane protein 91
chr10_+_91461413 0.17 ENST00000447580.1
kinesin family member 20B
chr13_-_48575401 0.17 ENST00000433022.1
ENST00000544100.1
succinate-CoA ligase, ADP-forming, beta subunit
chr4_+_78804393 0.16 ENST00000502384.1
mitochondrial ribosomal protein L1
chrX_-_19688475 0.16 ENST00000541422.1
SH3-domain kinase binding protein 1
chr2_+_58134756 0.16 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr5_+_35852797 0.16 ENST00000508941.1
interleukin 7 receptor
chr4_-_122085469 0.16 ENST00000057513.3
TNFAIP3 interacting protein 3
chr12_+_28410128 0.16 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr19_+_35225060 0.16 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr11_+_59705928 0.16 ENST00000398992.1
oocyte secreted protein 1
chr19_+_36132631 0.16 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ets variant 2
chr4_+_75174180 0.16 ENST00000413830.1
epithelial mitogen
chr6_+_126277842 0.16 ENST00000229633.5
histidine triad nucleotide binding protein 3
chr6_-_26216872 0.15 ENST00000244601.3
histone cluster 1, H2bg
chr2_+_109204909 0.15 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr9_+_26746951 0.15 ENST00000523363.1
RP11-18A15.1
chr17_-_72772462 0.15 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr5_-_86534822 0.15 ENST00000445770.2
Uncharacterized protein
chr11_+_128563652 0.15 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_79895097 0.15 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr8_-_61429315 0.15 ENST00000530725.1
ENST00000532232.1
RP11-163N6.2
chr6_-_26197478 0.15 ENST00000356476.2
histone cluster 1, H3d
chr13_-_25861530 0.15 ENST00000540661.1
myotubularin related protein 6
chr8_+_86019382 0.14 ENST00000360375.3
leucine rich repeat and coiled-coil centrosomal protein 1
chr16_-_11363178 0.14 ENST00000312693.3
transition protein 2 (during histone to protamine replacement)
chr15_+_44119159 0.14 ENST00000263795.6
ENST00000381246.2
ENST00000452115.1
WD repeat domain 76
chr20_+_56964169 0.14 ENST00000475243.1
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr3_-_146262488 0.14 ENST00000487389.1
phospholipid scramblase 1
chr11_-_45928830 0.14 ENST00000449465.1
chromosome 11 open reading frame 94
chr8_-_28965684 0.14 ENST00000523130.1
kinesin family member 13B
chr12_-_111142729 0.14 ENST00000546713.1
hydrogen voltage-gated channel 1
chr13_+_76413852 0.14 ENST00000533809.2
LIM domain 7
chr5_+_61874562 0.13 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr6_+_36839616 0.13 ENST00000359359.2
ENST00000510325.2
chromosome 6 open reading frame 89
chr11_-_10879572 0.13 ENST00000413761.2
zinc finger, BED-type containing 5
chr3_-_107777208 0.13 ENST00000398258.3
CD47 molecule
chr9_+_99690592 0.13 ENST00000354649.3
NUT family member 2G
chr17_+_47448102 0.13 ENST00000576461.1
Uncharacterized protein
chr3_+_14693247 0.13 ENST00000383794.3
ENST00000303688.7
coiled-coil domain containing 174
chr18_-_44500101 0.13 ENST00000589917.1
ENST00000587810.1
protein inhibitor of activated STAT, 2
chr16_+_14802801 0.13 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr5_+_69321361 0.13 ENST00000515588.1
small EDRK-rich factor 1B (centromeric)
chr17_-_72772425 0.13 ENST00000578822.1
N-acetyltransferase 9 (GCN5-related, putative)
chr6_-_11382478 0.12 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_131769256 0.12 ENST00000355771.3
Rho guanine nucleotide exchange factor (GEF) 4
chr19_-_42192096 0.12 ENST00000602225.1
carcinoembryonic antigen-related cell adhesion molecule 7
chr6_-_133035185 0.12 ENST00000367928.4
vanin 1
chr22_-_22292934 0.12 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr19_+_13858701 0.12 ENST00000586666.1
coiled-coil domain containing 130
chr3_+_136649311 0.12 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr14_+_39703084 0.12 ENST00000553728.1
cTAGE family member 5 isoform 4
chr8_-_123139423 0.12 ENST00000523792.1
RP11-398G24.2
chr4_-_170679024 0.12 ENST00000393381.2
chromosome 4 open reading frame 27
chr7_-_76247617 0.12 ENST00000441393.1
POM121 and ZP3 fusion
chr1_+_152975488 0.12 ENST00000542696.1
small proline-rich protein 3
chr19_+_41281060 0.12 ENST00000594436.1
ENST00000597784.1
melanoma inhibitory activity
chr4_-_38858428 0.12 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
toll-like receptor 6
toll-like receptor 1
chr14_+_96949319 0.12 ENST00000554706.1
adenylate kinase 7
chr7_+_141811539 0.12 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr19_+_13842559 0.12 ENST00000586600.1
coiled-coil domain containing 130
chr2_+_207220463 0.12 ENST00000598562.1
Uncharacterized protein
chr5_+_81601166 0.12 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr6_+_26440700 0.12 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr1_+_207943667 0.11 ENST00000462968.2
CD46 molecule, complement regulatory protein
chr11_-_72145426 0.11 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_-_156722195 0.11 ENST00000368206.5
hepatoma-derived growth factor
chr13_+_111893533 0.11 ENST00000478679.1
Rho guanine nucleotide exchange factor (GEF) 7
chr14_+_38264418 0.11 ENST00000267368.7
ENST00000382320.3
tetratricopeptide repeat domain 6
chr2_+_232573208 0.11 ENST00000409115.3
prothymosin, alpha
chr10_+_81462983 0.11 ENST00000448135.1
ENST00000429828.1
ENST00000372321.1
NUT family member 2B
chr19_-_42192189 0.11 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
carcinoembryonic antigen-related cell adhesion molecule 7
chr10_+_27793197 0.11 ENST00000356940.6
ENST00000535776.1
RAB18, member RAS oncogene family
chr17_-_37764128 0.11 ENST00000302584.4
neuronal differentiation 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.1 0.3 GO:0060585 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.4 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.2 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.3 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.2 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 1.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.1 GO:0089718 amino acid import across plasma membrane(GO:0089718)
0.0 0.0 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.0 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.3 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.0 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.0 0.0 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.5 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.0 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions