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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SMAD4

Z-value: 1.82

Motif logo

Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.9 SMAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48556470_48556640-0.911.2e-02Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_30752606 1.81 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157
coiled-coil domain containing 157
chr4_+_71384257 1.38 ENST00000339336.4
AMTN
amelotin
chr2_+_113735575 1.24 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr6_+_116937636 1.04 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr8_-_73793975 0.98 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr6_+_27791862 0.88 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr4_+_74606223 0.87 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr4_+_71384300 0.82 ENST00000504451.1
AMTN
amelotin
chr8_+_104383759 0.82 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr22_+_38382163 0.80 ENST00000333418.4
ENST00000427034.1
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
chr8_+_145726472 0.79 ENST00000528430.1
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr11_-_8739383 0.77 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr10_+_81892477 0.75 ENST00000372263.3
PLAC9
placenta-specific 9
chr12_-_106477805 0.74 ENST00000553094.1
ENST00000549704.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr17_-_65992544 0.73 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr19_-_51017127 0.73 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing
chr19_-_54984354 0.71 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr16_+_2880369 0.71 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr8_+_55466915 0.71 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr19_-_36643329 0.71 ENST00000589154.1
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr16_+_812506 0.71 ENST00000569566.1
MSLN
mesothelin
chr18_-_8337038 0.69 ENST00000594251.1
AP001094.1
Uncharacterized protein
chr1_-_153321301 0.66 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr17_-_73874654 0.63 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr19_-_6720686 0.60 ENST00000245907.6
C3
complement component 3
chr1_+_155100342 0.59 ENST00000368406.2
EFNA1
ephrin-A1
chr19_+_46171464 0.58 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
GIPR
gastric inhibitory polypeptide receptor
chr1_+_152956549 0.58 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr5_-_180242576 0.58 ENST00000514438.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr7_+_76109827 0.58 ENST00000446820.2
DTX2
deltex homolog 2 (Drosophila)
chr10_+_104180580 0.57 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr12_+_93115281 0.57 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr6_+_131571535 0.57 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr8_+_55467072 0.57 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr7_+_37723336 0.56 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr17_+_77018896 0.56 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_64053890 0.55 ENST00000438980.2
ENST00000313074.3
ENST00000542190.1
ENST00000541952.1
GPR137
G protein-coupled receptor 137
chr6_-_32908765 0.55 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_-_61647935 0.55 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr9_+_140119618 0.54 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr11_-_72385437 0.54 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr16_-_54963026 0.54 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr11_+_117070037 0.53 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr12_+_116985896 0.53 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chrX_-_128782722 0.53 ENST00000427399.1
APLN
apelin
chr17_+_74536115 0.52 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr5_+_177540444 0.52 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr8_+_104383728 0.52 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr19_-_6670128 0.52 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr2_+_220306238 0.52 ENST00000435853.1
SPEG
SPEG complex locus
chr3_-_112127981 0.52 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr22_-_50968419 0.51 ENST00000425169.1
ENST00000395680.1
ENST00000395681.1
ENST00000395678.3
ENST00000252029.3
TYMP
thymidine phosphorylase
chr19_+_49055332 0.51 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr5_-_121413974 0.51 ENST00000231004.4
LOX
lysyl oxidase
chr17_-_61777459 0.51 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr11_-_47270341 0.51 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
ACP2
acid phosphatase 2, lysosomal
chr12_-_53242770 0.50 ENST00000304620.4
ENST00000547110.1
KRT78
keratin 78
chr14_-_24732738 0.50 ENST00000558074.1
ENST00000560226.1
TGM1
transglutaminase 1
chr20_-_62199427 0.50 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr6_-_31651817 0.50 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr3_-_120400960 0.50 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr16_+_2880157 0.49 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr14_-_103989033 0.49 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chr15_-_74726283 0.49 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr12_-_42631529 0.48 ENST00000548917.1
YAF2
YY1 associated factor 2
chr5_+_140514782 0.48 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr6_-_31938700 0.48 ENST00000495340.1
DXO
decapping exoribonuclease
chr17_+_77020325 0.48 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_-_54824344 0.48 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr10_+_102891048 0.48 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr17_+_18128896 0.47 ENST00000316843.4
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr19_-_37178284 0.47 ENST00000425254.2
ENST00000590952.1
ENST00000433232.1
AC074138.3
AC074138.3
chr16_-_67881588 0.46 ENST00000561593.1
ENST00000565114.1
CENPT
centromere protein T
chr19_-_55672037 0.46 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr1_-_243418650 0.46 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr15_-_45670717 0.45 ENST00000558163.1
ENST00000558336.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_119699864 0.45 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr10_+_81891416 0.45 ENST00000372270.2
PLAC9
placenta-specific 9
chr7_+_94023873 0.44 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr12_+_104982622 0.44 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr17_+_38121772 0.44 ENST00000577447.1
GSDMA
gasdermin A
chr20_-_36794902 0.44 ENST00000373403.3
TGM2
transglutaminase 2
chr8_-_25281747 0.43 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr19_-_51529849 0.43 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr10_+_91087651 0.43 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr8_-_22550815 0.43 ENST00000317216.2
EGR3
early growth response 3
chr19_-_47231216 0.43 ENST00000594287.2
STRN4
striatin, calmodulin binding protein 4
chr1_+_155099927 0.43 ENST00000368407.3
EFNA1
ephrin-A1
chr14_-_91720224 0.43 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr12_+_6419877 0.42 ENST00000536531.1
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr12_-_66275350 0.42 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr16_-_66959429 0.42 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr16_-_25122735 0.42 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr17_+_77020224 0.42 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_46366918 0.42 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr19_+_40873617 0.41 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr2_-_113594279 0.41 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr11_+_46366799 0.41 ENST00000532868.2
DGKZ
diacylglycerol kinase, zeta
chr9_-_139268068 0.41 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
CARD9
caspase recruitment domain family, member 9
chr9_-_125240235 0.41 ENST00000259357.2
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr18_+_39739223 0.41 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907
chr5_-_142065612 0.40 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr1_-_113257905 0.40 ENST00000464951.1
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr16_+_29840929 0.40 ENST00000566252.1
MVP
major vault protein
chr15_-_45670924 0.40 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_+_31199037 0.40 ENST00000424224.1
OSBP2
oxysterol binding protein 2
chr6_+_139349903 0.40 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr1_+_10509971 0.40 ENST00000320498.4
CORT
cortistatin
chr6_+_13272904 0.39 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr9_+_118950325 0.39 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr14_+_77425972 0.39 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr3_+_150804676 0.38 ENST00000474524.1
ENST00000273432.4
MED12L
mediator complex subunit 12-like
chr20_+_34680698 0.38 ENST00000447825.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_+_66624527 0.37 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr17_+_47653178 0.36 ENST00000328741.5
NXPH3
neurexophilin 3
chr11_-_798305 0.36 ENST00000531514.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_+_45943169 0.36 ENST00000529052.1
ENST00000531526.1
GYLTL1B
glycosyltransferase-like 1B
chr12_-_52604607 0.36 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr16_-_57798253 0.36 ENST00000565270.1
KIFC3
kinesin family member C3
chr9_+_135754263 0.36 ENST00000356311.5
ENST00000350499.6
C9orf9
chromosome 9 open reading frame 9
chrX_-_153744434 0.36 ENST00000369643.1
ENST00000393572.1
FAM3A
family with sequence similarity 3, member A
chr22_-_33968239 0.36 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr9_-_140142222 0.35 ENST00000344774.4
ENST00000388932.2
FAM166A
family with sequence similarity 166, member A
chr19_+_55897699 0.35 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
RPL28
ribosomal protein L28
chr22_+_30752963 0.35 ENST00000445005.1
ENST00000430839.1
CCDC157
coiled-coil domain containing 157
chr19_-_47975106 0.35 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr16_-_68002456 0.35 ENST00000576616.1
ENST00000572037.1
ENST00000338335.3
ENST00000422611.2
ENST00000316341.3
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr19_-_2739992 0.34 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr17_-_79533608 0.34 ENST00000572760.1
ENST00000573876.1
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr19_+_49661079 0.34 ENST00000355712.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr8_-_144890847 0.34 ENST00000531942.1
SCRIB
scribbled planar cell polarity protein
chr8_+_72755367 0.34 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr19_+_49617581 0.34 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr1_+_201592013 0.34 ENST00000593583.1
AC096677.1
Uncharacterized protein ENSP00000471857
chr19_+_49661037 0.34 ENST00000427978.2
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr1_-_11751665 0.34 ENST00000376667.3
ENST00000235310.3
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr3_-_48598547 0.34 ENST00000536104.1
ENST00000452531.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr10_+_88718397 0.34 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr2_-_85108240 0.34 ENST00000409133.1
TRABD2A
TraB domain containing 2A
chr12_+_75874580 0.33 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr8_-_145028013 0.33 ENST00000354958.2
PLEC
plectin
chr7_+_20686946 0.33 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr4_+_57253672 0.33 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chr8_+_104384616 0.33 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr10_+_75670862 0.33 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
PLAU
plasminogen activator, urokinase
chrX_-_74145273 0.33 ENST00000055682.6
KIAA2022
KIAA2022
chr19_-_58864848 0.32 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr11_+_76493294 0.32 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr11_+_72929402 0.32 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr16_-_54320675 0.32 ENST00000329734.3
IRX3
iroquois homeobox 3
chr4_+_183370146 0.31 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr10_+_81892347 0.31 ENST00000372267.2
PLAC9
placenta-specific 9
chr19_-_47734448 0.31 ENST00000439096.2
BBC3
BCL2 binding component 3
chr11_-_798239 0.31 ENST00000531437.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_207095324 0.31 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr15_+_67420441 0.31 ENST00000558894.1
SMAD3
SMAD family member 3
chr8_+_118532937 0.31 ENST00000297347.3
MED30
mediator complex subunit 30
chr19_-_10227503 0.31 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr2_-_208030295 0.31 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr18_+_61223393 0.30 ENST00000269491.1
ENST00000382768.1
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr5_-_56778635 0.30 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr6_-_31612808 0.30 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr22_+_31644309 0.30 ENST00000425203.1
LIMK2
LIM domain kinase 2
chr19_-_6333614 0.30 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr16_-_30905584 0.30 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr1_-_150946911 0.30 ENST00000457392.1
ENST00000421609.1
CERS2
ceramide synthase 2
chr12_-_54813229 0.30 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr13_+_21750780 0.30 ENST00000309594.4
MRP63
mitochondrial ribosomal protein 63
chr1_-_44497024 0.30 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr18_+_77623668 0.30 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr1_+_96208646 0.30 ENST00000603401.1
RP11-286B14.2
RP11-286B14.2
chr2_+_119699742 0.30 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure
chr17_+_30813576 0.30 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_+_66124590 0.29 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_-_44031341 0.29 ENST00000600651.1
ETHE1
ethylmalonic encephalopathy 1
chr7_-_143956815 0.29 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr19_+_4229495 0.29 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr11_-_60623437 0.29 ENST00000332539.4
PTGDR2
prostaglandin D2 receptor 2
chr20_-_62203808 0.29 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr2_-_85108164 0.29 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr11_-_67276100 0.29 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr17_-_7760779 0.29 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr1_+_44457261 0.29 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr17_-_39942322 0.29 ENST00000449889.1
ENST00000465293.1
JUP
junction plakoglobin
chr17_+_9066252 0.29 ENST00000436734.1
NTN1
netrin 1
chr1_-_151119087 0.28 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr1_+_152691998 0.28 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr20_+_48789121 0.28 ENST00000411453.1
RP11-112L6.4
RP11-112L6.4
chr9_-_21368075 0.28 ENST00000449498.1
IFNA13
interferon, alpha 13
chr11_-_67120974 0.28 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr22_-_20731541 0.28 ENST00000292729.8
USP41
ubiquitin specific peptidase 41
chr19_-_49015050 0.28 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr15_-_40633101 0.28 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr11_-_64851496 0.28 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chr11_-_96239990 0.27 ENST00000511243.2
JRKL-AS1
JRKL antisense RNA 1
chr20_-_36794938 0.27 ENST00000453095.1
TGM2
transglutaminase 2
chr8_+_71383312 0.27 ENST00000520259.1
RP11-333A23.4
RP11-333A23.4
chr20_+_35090150 0.27 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr19_-_44031375 0.27 ENST00000292147.2
ETHE1
ethylmalonic encephalopathy 1
chr1_+_206643787 0.27 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.3 1.0 GO:0014028 notochord formation(GO:0014028)
0.3 0.9 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 1.0 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 0.8 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 1.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 0.7 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.2 0.9 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 0.6 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 1.5 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.5 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 0.7 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 0.4 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.7 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.8 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.4 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.4 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.3 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.6 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.5 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.4 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:1900148 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.2 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.2 GO:0002118 aggressive behavior(GO:0002118)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.2 GO:0038162 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.2 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.2 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0035931 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.0 GO:1904000 positive regulation of eating behavior(GO:1904000)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0021538 proprioception(GO:0019230) epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.2 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0046102 inosine metabolic process(GO:0046102)
0.0 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.5 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.5 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.0 0.4 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.5 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:2000291 myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.0 0.5 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.5 GO:0061061 muscle structure development(GO:0061061)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.6 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0048690 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.0 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.2 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0043318 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.9 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.0 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0031280 negative regulation of cyclase activity(GO:0031280)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.1 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 4.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.7 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.2 0.7 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 0.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.4 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.5 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.7 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 2.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.6 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism